Human papillomavirus 151

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Betapapillomavirus; Betapapillomavirus 2

Average proteome isoelectric point is 5.99

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|D3VNF8|D3VNF8_9PAPI Replication protein E1 OS=Human papillomavirus 151 OX=743812 GN=E1 PE=3 SV=1
MM1 pKa = 7.54IGKK4 pKa = 8.5QATLCDD10 pKa = 3.55IVLEE14 pKa = 4.14EE15 pKa = 4.64LVLPIDD21 pKa = 3.63LHH23 pKa = 4.95YY24 pKa = 11.06HH25 pKa = 5.86EE26 pKa = 5.87EE27 pKa = 4.19LPEE30 pKa = 4.2LPEE33 pKa = 3.88EE34 pKa = 4.26LEE36 pKa = 4.2EE37 pKa = 4.34VEE39 pKa = 5.05EE40 pKa = 4.29EE41 pKa = 4.78PEE43 pKa = 3.87YY44 pKa = 10.7TPYY47 pKa = 10.79KK48 pKa = 9.94IIVYY52 pKa = 10.32CGGCDD57 pKa = 3.17TKK59 pKa = 11.37LKK61 pKa = 10.35LHH63 pKa = 6.11VLATLSGIRR72 pKa = 11.84DD73 pKa = 4.02FQASLLGPVKK83 pKa = 10.18LLCPSCRR90 pKa = 11.84EE91 pKa = 3.84EE92 pKa = 3.77IRR94 pKa = 11.84NGRR97 pKa = 11.84RR98 pKa = 3.02

Molecular weight: 11.16 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|D3VNG0|D3VNG0_9PAPI Putative E4 product OS=Human papillomavirus 151 OX=743812 GN=E4 PE=4 SV=1
MM1 pKa = 7.64EE2 pKa = 5.49KK3 pKa = 10.66LNEE6 pKa = 4.15RR7 pKa = 11.84FSALQEE13 pKa = 4.13KK14 pKa = 10.62LMDD17 pKa = 4.3LYY19 pKa = 11.28EE20 pKa = 5.14SGVEE24 pKa = 3.96DD25 pKa = 5.76LEE27 pKa = 4.52TQIQHH32 pKa = 5.68WKK34 pKa = 10.34LLRR37 pKa = 11.84QEE39 pKa = 4.47QIIFYY44 pKa = 7.62YY45 pKa = 10.39ARR47 pKa = 11.84RR48 pKa = 11.84HH49 pKa = 5.25GIMRR53 pKa = 11.84LGYY56 pKa = 10.17QPVPPLATSEE66 pKa = 4.58SKK68 pKa = 11.13AKK70 pKa = 10.43DD71 pKa = 3.81AIAMGLLLEE80 pKa = 4.68SLQKK84 pKa = 10.89SKK86 pKa = 10.77FSEE89 pKa = 4.55EE90 pKa = 3.54PWTLVEE96 pKa = 4.34TSLEE100 pKa = 4.45TVRR103 pKa = 11.84SPPADD108 pKa = 3.59CFEE111 pKa = 4.94KK112 pKa = 10.69GPKK115 pKa = 9.47SVEE118 pKa = 4.01VYY120 pKa = 10.71FDD122 pKa = 3.98GDD124 pKa = 3.74PEE126 pKa = 4.3NVMSYY131 pKa = 7.39TVWTYY136 pKa = 10.83IYY138 pKa = 10.2YY139 pKa = 8.53QTDD142 pKa = 3.34DD143 pKa = 3.75EE144 pKa = 4.61TWAKK148 pKa = 10.79VEE150 pKa = 3.9GHH152 pKa = 5.76VDD154 pKa = 3.42YY155 pKa = 11.48AGAYY159 pKa = 8.77YY160 pKa = 9.79MEE162 pKa = 4.89GTFKK166 pKa = 10.29TYY168 pKa = 10.4YY169 pKa = 10.05IKK171 pKa = 10.91FEE173 pKa = 4.25TDD175 pKa = 2.4AKK177 pKa = 10.65RR178 pKa = 11.84YY179 pKa = 6.65GTTGYY184 pKa = 10.19WEE186 pKa = 3.87VHH188 pKa = 4.75VNKK191 pKa = 9.35DD192 pKa = 3.53TVFTPVTSSTPPAGVASQNPASEE215 pKa = 4.51PVSTSDD221 pKa = 3.29PAKK224 pKa = 9.04RR225 pKa = 11.84TSQATHH231 pKa = 4.52QRR233 pKa = 11.84YY234 pKa = 8.65GRR236 pKa = 11.84KK237 pKa = 9.43ASSPTVTSIRR247 pKa = 11.84AQKK250 pKa = 9.75RR251 pKa = 11.84RR252 pKa = 11.84QRR254 pKa = 11.84QRR256 pKa = 11.84QEE258 pKa = 3.52TPTRR262 pKa = 11.84QRR264 pKa = 11.84TNRR267 pKa = 11.84SRR269 pKa = 11.84SRR271 pKa = 11.84STEE274 pKa = 3.54RR275 pKa = 11.84RR276 pKa = 11.84GGRR279 pKa = 11.84ATRR282 pKa = 11.84RR283 pKa = 11.84SLSRR287 pKa = 11.84GSSKK291 pKa = 10.54SPRR294 pKa = 11.84RR295 pKa = 11.84GGRR298 pKa = 11.84SGGGPLTRR306 pKa = 11.84SRR308 pKa = 11.84SRR310 pKa = 11.84SRR312 pKa = 11.84SLTRR316 pKa = 11.84KK317 pKa = 8.35SANGGGVAPDD327 pKa = 3.36EE328 pKa = 4.47VGATVRR334 pKa = 11.84SISRR338 pKa = 11.84QHH340 pKa = 6.45SGRR343 pKa = 11.84LAQLLDD349 pKa = 3.62AAKK352 pKa = 9.99DD353 pKa = 3.57PPVILLRR360 pKa = 11.84GASNTLKK367 pKa = 10.38CYY369 pKa = 10.33RR370 pKa = 11.84YY371 pKa = 10.07RR372 pKa = 11.84FRR374 pKa = 11.84KK375 pKa = 8.72KK376 pKa = 9.81HH377 pKa = 5.83AGNFQLISTTWSWVGGHH394 pKa = 4.66TTDD397 pKa = 3.84RR398 pKa = 11.84IGRR401 pKa = 11.84ARR403 pKa = 11.84MLISFHH409 pKa = 6.87SNSEE413 pKa = 4.17RR414 pKa = 11.84EE415 pKa = 3.99TCLQQMKK422 pKa = 10.51LPLGVEE428 pKa = 4.08WSYY431 pKa = 11.91GQFDD435 pKa = 4.19DD436 pKa = 5.18LL437 pKa = 5.54

Molecular weight: 49.58 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2557

98

608

365.3

41.41

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.553 ± 0.524

2.034 ± 0.564

6.218 ± 0.467

6.727 ± 0.639

4.106 ± 0.599

6.101 ± 0.527

2.307 ± 0.21

5.084 ± 0.615

4.967 ± 0.753

8.76 ± 0.779

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.034 ± 0.429

3.442 ± 0.671

6.453 ± 1.146

5.084 ± 0.693

6.766 ± 0.81

7.587 ± 0.737

6.101 ± 0.988

5.866 ± 0.679

1.369 ± 0.311

3.442 ± 0.424
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski