Amino acid dipepetide frequency for Kinneretia asaccharophila

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.229AlaAla: 19.229 ± 0.211
1.299AlaCys: 1.299 ± 0.033
5.861AlaAsp: 5.861 ± 0.068
7.977AlaGlu: 7.977 ± 0.1
3.64AlaPhe: 3.64 ± 0.064
11.147AlaGly: 11.147 ± 0.131
2.622AlaHis: 2.622 ± 0.052
4.177AlaIle: 4.177 ± 0.063
3.678AlaLys: 3.678 ± 0.071
17.886AlaLeu: 17.886 ± 0.159
3.226AlaMet: 3.226 ± 0.056
2.477AlaAsn: 2.477 ± 0.047
6.855AlaPro: 6.855 ± 0.094
7.466AlaGln: 7.466 ± 0.1
10.004AlaArg: 10.004 ± 0.107
7.121AlaSer: 7.121 ± 0.09
5.041AlaThr: 5.041 ± 0.068
8.087AlaVal: 8.087 ± 0.092
2.265AlaTrp: 2.265 ± 0.051
2.496AlaTyr: 2.496 ± 0.045
0.0AlaXaa: 0.0 ± 0.0
Cys
1.092CysAla: 1.092 ± 0.03
0.116CysCys: 0.116 ± 0.008
0.436CysAsp: 0.436 ± 0.016
0.608CysGlu: 0.608 ± 0.021
0.301CysPhe: 0.301 ± 0.016
0.924CysGly: 0.924 ± 0.03
0.234CysHis: 0.234 ± 0.014
0.34CysIle: 0.34 ± 0.017
0.209CysLys: 0.209 ± 0.013
0.971CysLeu: 0.971 ± 0.031
0.183CysMet: 0.183 ± 0.01
0.21CysAsn: 0.21 ± 0.013
0.479CysPro: 0.479 ± 0.02
0.309CysGln: 0.309 ± 0.015
0.576CysArg: 0.576 ± 0.024
0.534CysSer: 0.534 ± 0.022
0.397CysThr: 0.397 ± 0.02
0.602CysVal: 0.602 ± 0.022
0.131CysTrp: 0.131 ± 0.01
0.183CysTyr: 0.183 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
6.486AspAla: 6.486 ± 0.074
0.471AspCys: 0.471 ± 0.021
2.077AspAsp: 2.077 ± 0.042
3.234AspGlu: 3.234 ± 0.056
1.979AspPhe: 1.979 ± 0.037
4.251AspGly: 4.251 ± 0.069
0.938AspHis: 0.938 ± 0.028
2.005AspIle: 2.005 ± 0.04
1.666AspLys: 1.666 ± 0.045
5.431AspLeu: 5.431 ± 0.068
1.033AspMet: 1.033 ± 0.027
1.002AspAsn: 1.002 ± 0.036
2.714AspPro: 2.714 ± 0.047
1.726AspGln: 1.726 ± 0.039
2.948AspArg: 2.948 ± 0.058
2.239AspSer: 2.239 ± 0.044
1.994AspThr: 1.994 ± 0.038
3.22AspVal: 3.22 ± 0.049
1.127AspTrp: 1.127 ± 0.033
1.362AspTyr: 1.362 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
8.297GluAla: 8.297 ± 0.104
0.363GluCys: 0.363 ± 0.018
2.411GluAsp: 2.411 ± 0.044
2.545GluGlu: 2.545 ± 0.059
1.83GluPhe: 1.83 ± 0.04
4.395GluGly: 4.395 ± 0.061
1.392GluHis: 1.392 ± 0.03
2.612GluIle: 2.612 ± 0.043
1.563GluLys: 1.563 ± 0.042
7.539GluLeu: 7.539 ± 0.092
1.144GluMet: 1.144 ± 0.031
1.11GluAsn: 1.11 ± 0.028
2.886GluPro: 2.886 ± 0.052
3.38GluGln: 3.38 ± 0.057
5.524GluArg: 5.524 ± 0.076
2.616GluSer: 2.616 ± 0.053
2.286GluThr: 2.286 ± 0.038
3.958GluVal: 3.958 ± 0.058
0.664GluTrp: 0.664 ± 0.024
0.957GluTyr: 0.957 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
3.927PheAla: 3.927 ± 0.049
0.362PheCys: 0.362 ± 0.016
2.092PheAsp: 2.092 ± 0.047
2.318PheGlu: 2.318 ± 0.043
1.254PhePhe: 1.254 ± 0.037
3.028PheGly: 3.028 ± 0.06
0.63PheHis: 0.63 ± 0.024
1.333PheIle: 1.333 ± 0.034
1.201PheLys: 1.201 ± 0.037
2.685PheLeu: 2.685 ± 0.053
0.713PheMet: 0.713 ± 0.026
1.018PheAsn: 1.018 ± 0.033
1.262PhePro: 1.262 ± 0.033
1.082PheGln: 1.082 ± 0.029
1.748PheArg: 1.748 ± 0.039
2.058PheSer: 2.058 ± 0.046
1.555PheThr: 1.555 ± 0.034
2.488PheVal: 2.488 ± 0.049
0.527PheTrp: 0.527 ± 0.02
0.821PheTyr: 0.821 ± 0.027
0.0PheXaa: 0.0 ± 0.0
Gly
9.435GlyAla: 9.435 ± 0.125
0.86GlyCys: 0.86 ± 0.027
3.682GlyAsp: 3.682 ± 0.061
4.925GlyGlu: 4.925 ± 0.066
3.122GlyPhe: 3.122 ± 0.057
7.215GlyGly: 7.215 ± 0.124
1.922GlyHis: 1.922 ± 0.042
3.141GlyIle: 3.141 ± 0.046
2.829GlyLys: 2.829 ± 0.054
11.189GlyLeu: 11.189 ± 0.125
2.061GlyMet: 2.061 ± 0.037
1.889GlyAsn: 1.889 ± 0.055
3.368GlyPro: 3.368 ± 0.057
4.187GlyGln: 4.187 ± 0.066
6.442GlyArg: 6.442 ± 0.072
5.046GlySer: 5.046 ± 0.093
3.661GlyThr: 3.661 ± 0.07
5.884GlyVal: 5.884 ± 0.066
1.544GlyTrp: 1.544 ± 0.039
2.124GlyTyr: 2.124 ± 0.048
0.0GlyXaa: 0.0 ± 0.0
His
2.732HisAla: 2.732 ± 0.046
0.293HisCys: 0.293 ± 0.016
0.967HisAsp: 0.967 ± 0.03
1.371HisGlu: 1.371 ± 0.032
0.78HisPhe: 0.78 ± 0.025
2.02HisGly: 2.02 ± 0.04
0.578HisHis: 0.578 ± 0.026
0.831HisIle: 0.831 ± 0.026
0.578HisLys: 0.578 ± 0.019
2.326HisLeu: 2.326 ± 0.048
0.46HisMet: 0.46 ± 0.021
0.445HisAsn: 0.445 ± 0.018
1.41HisPro: 1.41 ± 0.035
0.834HisGln: 0.834 ± 0.03
1.412HisArg: 1.412 ± 0.034
1.098HisSer: 1.098 ± 0.031
0.852HisThr: 0.852 ± 0.023
1.449HisVal: 1.449 ± 0.032
0.398HisTrp: 0.398 ± 0.018
0.636HisTyr: 0.636 ± 0.022
0.0HisXaa: 0.0 ± 0.0
Ile
5.227IleAla: 5.227 ± 0.07
0.358IleCys: 0.358 ± 0.015
2.326IleAsp: 2.326 ± 0.05
2.902IleGlu: 2.902 ± 0.044
1.072IlePhe: 1.072 ± 0.03
3.359IleGly: 3.359 ± 0.057
0.752IleHis: 0.752 ± 0.027
1.292IleIle: 1.292 ± 0.034
1.476IleLys: 1.476 ± 0.033
2.943IleLeu: 2.943 ± 0.05
0.642IleMet: 0.642 ± 0.021
1.242IleAsn: 1.242 ± 0.035
1.703IlePro: 1.703 ± 0.04
1.328IleGln: 1.328 ± 0.031
2.252IleArg: 2.252 ± 0.041
2.392IleSer: 2.392 ± 0.042
2.069IleThr: 2.069 ± 0.045
2.811IleVal: 2.811 ± 0.046
0.463IleTrp: 0.463 ± 0.02
0.843IleTyr: 0.843 ± 0.025
0.0IleXaa: 0.0 ± 0.0
Lys
3.785LysAla: 3.785 ± 0.077
0.134LysCys: 0.134 ± 0.011
1.394LysAsp: 1.394 ± 0.042
1.281LysGlu: 1.281 ± 0.038
0.831LysPhe: 0.831 ± 0.025
2.179LysGly: 2.179 ± 0.05
0.657LysHis: 0.657 ± 0.023
1.293LysIle: 1.293 ± 0.03
1.272LysLys: 1.272 ± 0.046
3.506LysLeu: 3.506 ± 0.057
0.627LysMet: 0.627 ± 0.024
0.85LysAsn: 0.85 ± 0.028
2.166LysPro: 2.166 ± 0.049
1.239LysGln: 1.239 ± 0.034
2.174LysArg: 2.174 ± 0.046
1.787LysSer: 1.787 ± 0.042
1.764LysThr: 1.764 ± 0.041
2.15LysVal: 2.15 ± 0.053
0.263LysTrp: 0.263 ± 0.016
0.543LysTyr: 0.543 ± 0.024
0.0LysXaa: 0.0 ± 0.0
Leu
17.172LeuAla: 17.172 ± 0.154
1.122LeuCys: 1.122 ± 0.032
6.499LeuAsp: 6.499 ± 0.073
6.122LeuGlu: 6.122 ± 0.077
3.267LeuPhe: 3.267 ± 0.062
10.325LeuGly: 10.325 ± 0.107
2.528LeuHis: 2.528 ± 0.058
4.478LeuIle: 4.478 ± 0.063
3.861LeuLys: 3.861 ± 0.061
14.751LeuLeu: 14.751 ± 0.167
2.886LeuMet: 2.886 ± 0.049
3.031LeuAsn: 3.031 ± 0.055
7.055LeuPro: 7.055 ± 0.09
5.782LeuGln: 5.782 ± 0.089
9.931LeuArg: 9.931 ± 0.12
8.122LeuSer: 8.122 ± 0.107
4.604LeuThr: 4.604 ± 0.068
7.702LeuVal: 7.702 ± 0.079
1.554LeuTrp: 1.554 ± 0.041
2.053LeuTyr: 2.053 ± 0.039
0.0LeuXaa: 0.0 ± 0.0
Met
2.888MetAla: 2.888 ± 0.048
0.134MetCys: 0.134 ± 0.009
1.098MetAsp: 1.098 ± 0.033
0.971MetGlu: 0.971 ± 0.028
0.612MetPhe: 0.612 ± 0.022
1.766MetGly: 1.766 ± 0.039
0.489MetHis: 0.489 ± 0.019
0.814MetIle: 0.814 ± 0.026
0.876MetLys: 0.876 ± 0.03
2.612MetLeu: 2.612 ± 0.048
0.519MetMet: 0.519 ± 0.023
0.753MetAsn: 0.753 ± 0.024
1.355MetPro: 1.355 ± 0.033
1.094MetGln: 1.094 ± 0.03
1.627MetArg: 1.627 ± 0.033
1.836MetSer: 1.836 ± 0.038
1.04MetThr: 1.04 ± 0.028
1.475MetVal: 1.475 ± 0.032
0.175MetTrp: 0.175 ± 0.011
0.322MetTyr: 0.322 ± 0.018
0.0MetXaa: 0.0 ± 0.0
Asn
2.946AsnAla: 2.946 ± 0.062
0.211AsnCys: 0.211 ± 0.012
1.014AsnAsp: 1.014 ± 0.025
1.215AsnGlu: 1.215 ± 0.031
0.801AsnPhe: 0.801 ± 0.026
1.901AsnGly: 1.901 ± 0.048
0.463AsnHis: 0.463 ± 0.018
1.025AsnIle: 1.025 ± 0.036
0.806AsnLys: 0.806 ± 0.028
2.536AsnLeu: 2.536 ± 0.053
0.451AsnMet: 0.451 ± 0.019
0.693AsnAsn: 0.693 ± 0.031
1.661AsnPro: 1.661 ± 0.037
0.85AsnGln: 0.85 ± 0.026
1.489AsnArg: 1.489 ± 0.034
1.243AsnSer: 1.243 ± 0.039
1.282AsnThr: 1.282 ± 0.037
1.568AsnVal: 1.568 ± 0.035
0.372AsnTrp: 0.372 ± 0.019
0.631AsnTyr: 0.631 ± 0.026
0.0AsnXaa: 0.0 ± 0.0
Pro
7.883ProAla: 7.883 ± 0.103
0.356ProCys: 0.356 ± 0.018
2.874ProAsp: 2.874 ± 0.05
3.938ProGlu: 3.938 ± 0.06
1.579ProPhe: 1.579 ± 0.036
4.99ProGly: 4.99 ± 0.069
1.042ProHis: 1.042 ± 0.027
1.584ProIle: 1.584 ± 0.034
1.433ProLys: 1.433 ± 0.037
6.07ProLeu: 6.07 ± 0.087
1.212ProMet: 1.212 ± 0.028
1.079ProAsn: 1.079 ± 0.031
2.788ProPro: 2.788 ± 0.067
2.563ProGln: 2.563 ± 0.056
3.379ProArg: 3.379 ± 0.061
2.853ProSer: 2.853 ± 0.048
2.231ProThr: 2.231 ± 0.046
3.909ProVal: 3.909 ± 0.059
0.848ProTrp: 0.848 ± 0.028
1.049ProTyr: 1.049 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
7.752GlnAla: 7.752 ± 0.111
0.278GlnCys: 0.278 ± 0.014
2.013GlnAsp: 2.013 ± 0.047
1.885GlnGlu: 1.885 ± 0.04
1.309GlnPhe: 1.309 ± 0.032
4.253GlnGly: 4.253 ± 0.067
1.045GlnHis: 1.045 ± 0.03
1.903GlnIle: 1.903 ± 0.037
0.879GlnLys: 0.879 ± 0.029
5.833GlnLeu: 5.833 ± 0.093
0.978GlnMet: 0.978 ± 0.028
0.745GlnAsn: 0.745 ± 0.026
2.659GlnPro: 2.659 ± 0.047
2.498GlnGln: 2.498 ± 0.055
4.519GlnArg: 4.519 ± 0.071
2.177GlnSer: 2.177 ± 0.043
2.067GlnThr: 2.067 ± 0.043
3.154GlnVal: 3.154 ± 0.053
0.689GlnTrp: 0.689 ± 0.023
0.742GlnTyr: 0.742 ± 0.027
0.0GlnXaa: 0.0 ± 0.0
Arg
8.82ArgAla: 8.82 ± 0.085
0.7ArgCys: 0.7 ± 0.026
3.446ArgAsp: 3.446 ± 0.051
5.131ArgGlu: 5.131 ± 0.072
2.748ArgPhe: 2.748 ± 0.051
5.217ArgGly: 5.217 ± 0.062
1.932ArgHis: 1.932 ± 0.04
3.009ArgIle: 3.009 ± 0.049
1.746ArgLys: 1.746 ± 0.041
10.008ArgLeu: 10.008 ± 0.123
1.833ArgMet: 1.833 ± 0.038
1.593ArgAsn: 1.593 ± 0.032
3.785ArgPro: 3.785 ± 0.062
3.747ArgGln: 3.747 ± 0.058
5.896ArgArg: 5.896 ± 0.086
3.99ArgSer: 3.99 ± 0.065
2.402ArgThr: 2.402 ± 0.042
5.104ArgVal: 5.104 ± 0.063
1.413ArgTrp: 1.413 ± 0.034
1.908ArgTyr: 1.908 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
7.034SerAla: 7.034 ± 0.088
0.493SerCys: 0.493 ± 0.02
2.546SerAsp: 2.546 ± 0.042
3.019SerGlu: 3.019 ± 0.05
2.138SerPhe: 2.138 ± 0.049
5.456SerGly: 5.456 ± 0.085
1.177SerHis: 1.177 ± 0.029
2.025SerIle: 2.025 ± 0.04
1.658SerLys: 1.658 ± 0.038
7.123SerLeu: 7.123 ± 0.091
1.219SerMet: 1.219 ± 0.032
1.387SerAsn: 1.387 ± 0.039
3.145SerPro: 3.145 ± 0.053
2.33SerGln: 2.33 ± 0.043
3.825SerArg: 3.825 ± 0.062
3.458SerSer: 3.458 ± 0.07
2.726SerThr: 2.726 ± 0.051
3.616SerVal: 3.616 ± 0.058
0.897SerTrp: 0.897 ± 0.027
1.331SerTyr: 1.331 ± 0.04
0.0SerXaa: 0.0 ± 0.0
Thr
5.138ThrAla: 5.138 ± 0.066
0.291ThrCys: 0.291 ± 0.015
1.832ThrAsp: 1.832 ± 0.04
2.24ThrGlu: 2.24 ± 0.039
1.167ThrPhe: 1.167 ± 0.033
3.905ThrGly: 3.905 ± 0.064
0.914ThrHis: 0.914 ± 0.026
1.534ThrIle: 1.534 ± 0.042
1.011ThrLys: 1.011 ± 0.033
6.003ThrLeu: 6.003 ± 0.078
0.821ThrMet: 0.821 ± 0.024
0.907ThrAsn: 0.907 ± 0.027
3.153ThrPro: 3.153 ± 0.05
1.886ThrGln: 1.886 ± 0.04
2.909ThrArg: 2.909 ± 0.048
2.105ThrSer: 2.105 ± 0.049
2.01ThrThr: 2.01 ± 0.056
3.548ThrVal: 3.548 ± 0.057
0.527ThrTrp: 0.527 ± 0.019
0.749ThrTyr: 0.749 ± 0.026
0.0ThrXaa: 0.0 ± 0.0
Val
8.478ValAla: 8.478 ± 0.091
0.64ValCys: 0.64 ± 0.022
3.693ValAsp: 3.693 ± 0.052
3.938ValGlu: 3.938 ± 0.063
2.415ValPhe: 2.415 ± 0.046
5.249ValGly: 5.249 ± 0.071
1.412ValHis: 1.412 ± 0.037
2.799ValIle: 2.799 ± 0.045
2.085ValLys: 2.085 ± 0.05
8.694ValLeu: 8.694 ± 0.097
1.66ValMet: 1.66 ± 0.036
1.791ValAsn: 1.791 ± 0.037
3.394ValPro: 3.394 ± 0.053
3.141ValGln: 3.141 ± 0.051
4.586ValArg: 4.586 ± 0.06
4.015ValSer: 4.015 ± 0.065
2.888ValThr: 2.888 ± 0.056
5.009ValVal: 5.009 ± 0.082
0.944ValTrp: 0.944 ± 0.029
1.395ValTyr: 1.395 ± 0.031
0.0ValXaa: 0.0 ± 0.0
Trp
1.663TrpAla: 1.663 ± 0.042
0.153TrpCys: 0.153 ± 0.011
0.623TrpAsp: 0.623 ± 0.022
0.594TrpGlu: 0.594 ± 0.019
0.49TrpPhe: 0.49 ± 0.017
1.025TrpGly: 1.025 ± 0.028
0.352TrpHis: 0.352 ± 0.016
0.569TrpIle: 0.569 ± 0.021
0.403TrpLys: 0.403 ± 0.019
2.392TrpLeu: 2.392 ± 0.047
0.408TrpMet: 0.408 ± 0.017
0.388TrpAsn: 0.388 ± 0.017
0.794TrpPro: 0.794 ± 0.026
0.976TrpGln: 0.976 ± 0.029
1.474TrpArg: 1.474 ± 0.036
0.827TrpSer: 0.827 ± 0.026
0.677TrpThr: 0.677 ± 0.024
1.085TrpVal: 1.085 ± 0.032
0.3TrpTrp: 0.3 ± 0.017
0.263TrpTyr: 0.263 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.567TyrAla: 2.567 ± 0.051
0.201TyrCys: 0.201 ± 0.012
1.018TyrAsp: 1.018 ± 0.032
1.261TyrGlu: 1.261 ± 0.03
0.764TyrPhe: 0.764 ± 0.027
1.922TyrGly: 1.922 ± 0.043
0.395TyrHis: 0.395 ± 0.018
0.688TyrIle: 0.688 ± 0.025
0.665TyrLys: 0.665 ± 0.026
2.347TyrLeu: 2.347 ± 0.044
0.378TyrMet: 0.378 ± 0.017
0.549TyrAsn: 0.549 ± 0.023
1.027TyrPro: 1.027 ± 0.026
0.959TyrGln: 0.959 ± 0.031
1.713TyrArg: 1.713 ± 0.033
1.087TyrSer: 1.087 ± 0.031
1.104TyrThr: 1.104 ± 0.028
1.409TyrVal: 1.409 ± 0.032
0.353TyrTrp: 0.353 ± 0.017
0.521TyrTyr: 0.521 ± 0.021
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3851 proteins (1324798 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski