Amino acid dipepetide frequency for Porcine mastadenovirus B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.264AlaAla: 7.264 ± 0.611
1.434AlaCys: 1.434 ± 0.429
3.727AlaAsp: 3.727 ± 0.465
4.492AlaGlu: 4.492 ± 0.932
3.058AlaPhe: 3.058 ± 0.529
4.396AlaGly: 4.396 ± 0.624
1.434AlaHis: 1.434 ± 0.355
3.058AlaIle: 3.058 ± 0.752
2.103AlaLys: 2.103 ± 0.449
7.359AlaLeu: 7.359 ± 0.696
2.007AlaMet: 2.007 ± 0.545
2.581AlaAsn: 2.581 ± 0.501
6.308AlaPro: 6.308 ± 1.294
3.058AlaGln: 3.058 ± 0.479
4.683AlaArg: 4.683 ± 0.552
6.021AlaSer: 6.021 ± 0.604
3.919AlaThr: 3.919 ± 0.566
5.352AlaVal: 5.352 ± 0.814
1.242AlaTrp: 1.242 ± 0.311
3.536AlaTyr: 3.536 ± 0.531
0.0AlaXaa: 0.0 ± 0.0
Cys
1.911CysAla: 1.911 ± 0.476
0.956CysCys: 0.956 ± 0.367
1.338CysAsp: 1.338 ± 0.375
1.147CysGlu: 1.147 ± 0.452
0.956CysPhe: 0.956 ± 0.315
1.434CysGly: 1.434 ± 0.534
0.287CysHis: 0.287 ± 0.159
0.573CysIle: 0.573 ± 0.193
0.478CysLys: 0.478 ± 0.25
1.816CysLeu: 1.816 ± 0.436
0.669CysMet: 0.669 ± 0.268
1.147CysAsn: 1.147 ± 0.367
1.242CysPro: 1.242 ± 0.337
0.382CysGln: 0.382 ± 0.197
0.956CysArg: 0.956 ± 0.356
1.529CysSer: 1.529 ± 0.419
0.86CysThr: 0.86 ± 0.371
0.956CysVal: 0.956 ± 0.359
0.191CysTrp: 0.191 ± 0.187
1.529CysTyr: 1.529 ± 0.288
0.0CysXaa: 0.0 ± 0.0
Asp
4.014AspAla: 4.014 ± 0.586
0.765AspCys: 0.765 ± 0.257
1.72AspAsp: 1.72 ± 0.45
3.25AspGlu: 3.25 ± 0.61
2.103AspPhe: 2.103 ± 0.412
3.345AspGly: 3.345 ± 0.658
1.529AspHis: 1.529 ± 0.428
3.058AspIle: 3.058 ± 0.507
1.147AspLys: 1.147 ± 0.417
5.257AspLeu: 5.257 ± 0.765
1.338AspMet: 1.338 ± 0.378
2.198AspAsn: 2.198 ± 0.598
4.11AspPro: 4.11 ± 0.514
2.007AspGln: 2.007 ± 0.446
1.911AspArg: 1.911 ± 0.452
4.11AspSer: 4.11 ± 0.525
2.581AspThr: 2.581 ± 0.538
3.919AspVal: 3.919 ± 0.647
0.478AspTrp: 0.478 ± 0.2
2.389AspTyr: 2.389 ± 0.474
0.0AspXaa: 0.0 ± 0.0
Glu
5.065GluAla: 5.065 ± 0.687
1.051GluCys: 1.051 ± 0.37
4.11GluAsp: 4.11 ± 0.783
6.212GluGlu: 6.212 ± 1.302
1.434GluPhe: 1.434 ± 0.277
3.823GluGly: 3.823 ± 0.565
0.478GluHis: 0.478 ± 0.185
2.772GluIle: 2.772 ± 0.394
2.294GluLys: 2.294 ± 0.485
5.161GluLeu: 5.161 ± 0.771
1.816GluMet: 1.816 ± 0.38
2.007GluAsn: 2.007 ± 0.464
3.441GluPro: 3.441 ± 0.771
2.389GluGln: 2.389 ± 0.414
2.103GluArg: 2.103 ± 0.379
2.963GluSer: 2.963 ± 0.629
3.727GluThr: 3.727 ± 0.539
3.25GluVal: 3.25 ± 0.602
0.478GluTrp: 0.478 ± 0.228
0.956GluTyr: 0.956 ± 0.37
0.0GluXaa: 0.0 ± 0.0
Phe
2.294PheAla: 2.294 ± 0.394
1.434PheCys: 1.434 ± 0.395
2.772PheAsp: 2.772 ± 0.415
1.816PheGlu: 1.816 ± 0.322
1.72PhePhe: 1.72 ± 0.369
1.434PheGly: 1.434 ± 0.367
1.338PheHis: 1.338 ± 0.315
2.103PheIle: 2.103 ± 0.424
1.338PheLys: 1.338 ± 0.322
3.919PheLeu: 3.919 ± 0.697
1.242PheMet: 1.242 ± 0.243
2.007PheAsn: 2.007 ± 0.35
2.581PhePro: 2.581 ± 0.419
2.389PheGln: 2.389 ± 0.487
2.867PheArg: 2.867 ± 0.562
2.198PheSer: 2.198 ± 0.384
2.294PheThr: 2.294 ± 0.557
2.007PheVal: 2.007 ± 0.38
0.191PheTrp: 0.191 ± 0.115
1.147PheTyr: 1.147 ± 0.255
0.0PheXaa: 0.0 ± 0.0
Gly
4.492GlyAla: 4.492 ± 0.663
0.86GlyCys: 0.86 ± 0.285
3.632GlyAsp: 3.632 ± 0.497
2.676GlyGlu: 2.676 ± 0.602
2.294GlyPhe: 2.294 ± 0.384
4.588GlyGly: 4.588 ± 0.612
1.816GlyHis: 1.816 ± 0.532
1.911GlyIle: 1.911 ± 0.373
2.485GlyLys: 2.485 ± 0.694
5.161GlyLeu: 5.161 ± 0.855
1.147GlyMet: 1.147 ± 0.369
2.867GlyAsn: 2.867 ± 0.626
4.205GlyPro: 4.205 ± 0.707
3.632GlyGln: 3.632 ± 0.895
4.205GlyArg: 4.205 ± 0.638
4.874GlySer: 4.874 ± 0.663
3.727GlyThr: 3.727 ± 0.715
4.779GlyVal: 4.779 ± 0.728
0.765GlyTrp: 0.765 ± 0.254
1.338GlyTyr: 1.338 ± 0.458
0.0GlyXaa: 0.0 ± 0.0
His
1.529HisAla: 1.529 ± 0.394
0.669HisCys: 0.669 ± 0.265
1.051HisAsp: 1.051 ± 0.265
1.242HisGlu: 1.242 ± 0.31
0.956HisPhe: 0.956 ± 0.276
1.816HisGly: 1.816 ± 0.395
0.86HisHis: 0.86 ± 0.267
1.338HisIle: 1.338 ± 0.421
0.382HisLys: 0.382 ± 0.163
3.058HisLeu: 3.058 ± 0.504
0.478HisMet: 0.478 ± 0.207
1.625HisAsn: 1.625 ± 0.304
2.103HisPro: 2.103 ± 0.535
1.147HisGln: 1.147 ± 0.272
2.485HisArg: 2.485 ± 0.468
2.007HisSer: 2.007 ± 0.383
1.338HisThr: 1.338 ± 0.4
1.72HisVal: 1.72 ± 0.465
0.573HisTrp: 0.573 ± 0.295
0.669HisTyr: 0.669 ± 0.186
0.0HisXaa: 0.0 ± 0.0
Ile
2.581IleAla: 2.581 ± 0.5
0.573IleCys: 0.573 ± 0.199
1.72IleAsp: 1.72 ± 0.552
2.103IleGlu: 2.103 ± 0.533
1.529IlePhe: 1.529 ± 0.533
2.294IleGly: 2.294 ± 0.649
0.669IleHis: 0.669 ± 0.189
1.242IleIle: 1.242 ± 0.387
1.911IleLys: 1.911 ± 0.35
4.11IleLeu: 4.11 ± 0.642
0.669IleMet: 0.669 ± 0.181
1.338IleAsn: 1.338 ± 0.299
2.294IlePro: 2.294 ± 0.445
1.911IleGln: 1.911 ± 0.441
2.294IleArg: 2.294 ± 0.486
3.154IleSer: 3.154 ± 0.54
3.536IleThr: 3.536 ± 0.692
2.198IleVal: 2.198 ± 0.469
0.478IleTrp: 0.478 ± 0.222
1.529IleTyr: 1.529 ± 0.302
0.0IleXaa: 0.0 ± 0.0
Lys
2.389LysAla: 2.389 ± 0.639
0.573LysCys: 0.573 ± 0.257
2.581LysAsp: 2.581 ± 0.388
2.103LysGlu: 2.103 ± 0.44
1.625LysPhe: 1.625 ± 0.454
1.911LysGly: 1.911 ± 0.453
0.956LysHis: 0.956 ± 0.256
2.485LysIle: 2.485 ± 0.561
2.294LysLys: 2.294 ± 0.438
3.632LysLeu: 3.632 ± 0.657
0.765LysMet: 0.765 ± 0.246
1.338LysAsn: 1.338 ± 0.243
1.72LysPro: 1.72 ± 0.434
1.529LysGln: 1.529 ± 0.478
2.867LysArg: 2.867 ± 0.742
2.007LysSer: 2.007 ± 0.457
1.72LysThr: 1.72 ± 0.371
2.198LysVal: 2.198 ± 0.415
0.096LysTrp: 0.096 ± 0.078
0.765LysTyr: 0.765 ± 0.385
0.0LysXaa: 0.0 ± 0.0
Leu
6.69LeuAla: 6.69 ± 0.806
1.911LeuCys: 1.911 ± 0.372
4.97LeuAsp: 4.97 ± 0.485
5.257LeuGlu: 5.257 ± 0.862
3.345LeuPhe: 3.345 ± 0.563
5.543LeuGly: 5.543 ± 0.629
3.345LeuHis: 3.345 ± 0.59
2.772LeuIle: 2.772 ± 0.551
3.823LeuLys: 3.823 ± 0.647
8.315LeuLeu: 8.315 ± 0.964
3.345LeuMet: 3.345 ± 0.658
3.058LeuAsn: 3.058 ± 0.515
7.359LeuPro: 7.359 ± 0.767
5.734LeuGln: 5.734 ± 0.7
7.073LeuArg: 7.073 ± 0.829
7.359LeuSer: 7.359 ± 0.725
5.926LeuThr: 5.926 ± 0.93
6.308LeuVal: 6.308 ± 0.926
1.911LeuTrp: 1.911 ± 0.376
3.345LeuTyr: 3.345 ± 0.652
0.0LeuXaa: 0.0 ± 0.0
Met
2.772MetAla: 2.772 ± 0.439
0.382MetCys: 0.382 ± 0.168
2.103MetAsp: 2.103 ± 0.506
1.242MetGlu: 1.242 ± 0.267
0.669MetPhe: 0.669 ± 0.292
1.72MetGly: 1.72 ± 0.378
0.765MetHis: 0.765 ± 0.246
0.573MetIle: 0.573 ± 0.189
0.669MetLys: 0.669 ± 0.27
2.485MetLeu: 2.485 ± 0.466
0.765MetMet: 0.765 ± 0.332
0.956MetAsn: 0.956 ± 0.358
1.72MetPro: 1.72 ± 0.388
1.147MetGln: 1.147 ± 0.359
1.051MetArg: 1.051 ± 0.292
2.007MetSer: 2.007 ± 0.429
1.147MetThr: 1.147 ± 0.242
1.242MetVal: 1.242 ± 0.342
0.382MetTrp: 0.382 ± 0.175
0.669MetTyr: 0.669 ± 0.231
0.0MetXaa: 0.0 ± 0.0
Asn
1.147AsnAla: 1.147 ± 0.293
1.242AsnCys: 1.242 ± 0.475
1.529AsnAsp: 1.529 ± 0.577
1.242AsnGlu: 1.242 ± 0.298
1.911AsnPhe: 1.911 ± 0.527
2.485AsnGly: 2.485 ± 0.453
0.956AsnHis: 0.956 ± 0.386
2.007AsnIle: 2.007 ± 0.391
1.434AsnLys: 1.434 ± 0.395
3.536AsnLeu: 3.536 ± 0.74
0.956AsnMet: 0.956 ± 0.249
1.242AsnAsn: 1.242 ± 0.403
3.058AsnPro: 3.058 ± 0.5
1.529AsnGln: 1.529 ± 0.409
2.389AsnArg: 2.389 ± 0.459
2.676AsnSer: 2.676 ± 0.449
1.816AsnThr: 1.816 ± 0.371
2.772AsnVal: 2.772 ± 0.619
0.765AsnTrp: 0.765 ± 0.318
1.816AsnTyr: 1.816 ± 0.499
0.0AsnXaa: 0.0 ± 0.0
Pro
7.933ProAla: 7.933 ± 1.26
1.051ProCys: 1.051 ± 0.334
3.345ProAsp: 3.345 ± 0.548
5.065ProGlu: 5.065 ± 0.532
2.581ProPhe: 2.581 ± 0.564
4.205ProGly: 4.205 ± 0.732
1.529ProHis: 1.529 ± 0.341
1.529ProIle: 1.529 ± 0.434
1.911ProLys: 1.911 ± 0.532
5.926ProLeu: 5.926 ± 0.738
1.147ProMet: 1.147 ± 0.38
2.103ProAsn: 2.103 ± 0.396
8.124ProPro: 8.124 ± 1.316
3.441ProGln: 3.441 ± 0.58
4.97ProArg: 4.97 ± 0.807
6.212ProSer: 6.212 ± 1.168
5.448ProThr: 5.448 ± 0.86
6.117ProVal: 6.117 ± 0.831
0.956ProTrp: 0.956 ± 0.331
1.529ProTyr: 1.529 ± 0.468
0.0ProXaa: 0.0 ± 0.0
Gln
4.396GlnAla: 4.396 ± 0.556
0.956GlnCys: 0.956 ± 0.332
2.103GlnAsp: 2.103 ± 0.417
2.772GlnGlu: 2.772 ± 0.456
1.434GlnPhe: 1.434 ± 0.385
3.441GlnGly: 3.441 ± 0.518
0.956GlnHis: 0.956 ± 0.33
2.485GlnIle: 2.485 ± 0.631
2.007GlnLys: 2.007 ± 0.463
4.588GlnLeu: 4.588 ± 0.806
1.051GlnMet: 1.051 ± 0.247
1.434GlnAsn: 1.434 ± 0.546
4.014GlnPro: 4.014 ± 0.66
2.581GlnGln: 2.581 ± 0.466
3.441GlnArg: 3.441 ± 0.38
3.058GlnSer: 3.058 ± 0.563
4.396GlnThr: 4.396 ± 0.497
2.198GlnVal: 2.198 ± 0.522
0.573GlnTrp: 0.573 ± 0.281
1.338GlnTyr: 1.338 ± 0.399
0.0GlnXaa: 0.0 ± 0.0
Arg
5.257ArgAla: 5.257 ± 0.811
1.434ArgCys: 1.434 ± 0.354
3.441ArgAsp: 3.441 ± 0.709
2.676ArgGlu: 2.676 ± 0.517
2.294ArgPhe: 2.294 ± 0.475
3.727ArgGly: 3.727 ± 0.608
2.198ArgHis: 2.198 ± 0.65
1.816ArgIle: 1.816 ± 0.578
2.963ArgLys: 2.963 ± 0.529
8.028ArgLeu: 8.028 ± 0.882
0.573ArgMet: 0.573 ± 0.241
2.389ArgAsn: 2.389 ± 0.587
4.301ArgPro: 4.301 ± 0.858
3.441ArgGln: 3.441 ± 0.589
8.793ArgArg: 8.793 ± 1.959
3.823ArgSer: 3.823 ± 0.693
2.867ArgThr: 2.867 ± 0.711
3.345ArgVal: 3.345 ± 0.673
0.956ArgTrp: 0.956 ± 0.233
2.007ArgTyr: 2.007 ± 0.447
0.0ArgXaa: 0.0 ± 0.0
Ser
6.499SerAla: 6.499 ± 0.773
1.529SerCys: 1.529 ± 0.404
2.676SerAsp: 2.676 ± 0.494
3.345SerGlu: 3.345 ± 0.631
3.25SerPhe: 3.25 ± 0.398
5.161SerGly: 5.161 ± 0.592
2.963SerHis: 2.963 ± 0.796
2.772SerIle: 2.772 ± 0.552
2.676SerLys: 2.676 ± 0.706
8.028SerLeu: 8.028 ± 1.042
2.103SerMet: 2.103 ± 0.595
2.103SerAsn: 2.103 ± 0.569
4.683SerPro: 4.683 ± 0.543
3.154SerGln: 3.154 ± 0.6
4.492SerArg: 4.492 ± 1.009
6.021SerSer: 6.021 ± 0.895
4.396SerThr: 4.396 ± 0.659
4.779SerVal: 4.779 ± 0.663
1.338SerTrp: 1.338 ± 0.333
2.485SerTyr: 2.485 ± 0.589
0.0SerXaa: 0.0 ± 0.0
Thr
5.065ThrAla: 5.065 ± 0.496
1.529ThrCys: 1.529 ± 0.421
1.529ThrAsp: 1.529 ± 0.289
3.25ThrGlu: 3.25 ± 0.55
3.25ThrPhe: 3.25 ± 0.472
3.823ThrGly: 3.823 ± 0.76
1.434ThrHis: 1.434 ± 0.251
1.72ThrIle: 1.72 ± 0.468
1.434ThrLys: 1.434 ± 0.398
7.073ThrLeu: 7.073 ± 1.129
1.147ThrMet: 1.147 ± 0.383
1.816ThrAsn: 1.816 ± 0.434
6.308ThrPro: 6.308 ± 0.9
3.154ThrGln: 3.154 ± 0.642
2.963ThrArg: 2.963 ± 0.5
5.257ThrSer: 5.257 ± 0.937
2.581ThrThr: 2.581 ± 0.459
4.396ThrVal: 4.396 ± 0.637
0.478ThrTrp: 0.478 ± 0.274
2.581ThrTyr: 2.581 ± 0.856
0.0ThrXaa: 0.0 ± 0.0
Val
3.536ValAla: 3.536 ± 0.766
1.338ValCys: 1.338 ± 0.439
3.154ValAsp: 3.154 ± 0.595
3.823ValGlu: 3.823 ± 0.531
2.198ValPhe: 2.198 ± 0.39
3.058ValGly: 3.058 ± 0.54
1.72ValHis: 1.72 ± 0.533
2.867ValIle: 2.867 ± 0.469
2.485ValLys: 2.485 ± 0.518
5.257ValLeu: 5.257 ± 0.824
1.147ValMet: 1.147 ± 0.311
2.772ValAsn: 2.772 ± 0.728
5.352ValPro: 5.352 ± 0.687
3.823ValGln: 3.823 ± 0.633
4.014ValArg: 4.014 ± 0.759
5.161ValSer: 5.161 ± 0.907
5.065ValThr: 5.065 ± 0.592
4.301ValVal: 4.301 ± 0.641
0.573ValTrp: 0.573 ± 0.231
2.581ValTyr: 2.581 ± 0.385
0.0ValXaa: 0.0 ± 0.0
Trp
0.573TrpAla: 0.573 ± 0.243
0.191TrpCys: 0.191 ± 0.127
0.86TrpAsp: 0.86 ± 0.237
0.86TrpGlu: 0.86 ± 0.394
0.191TrpPhe: 0.191 ± 0.134
1.338TrpGly: 1.338 ± 0.461
0.382TrpHis: 0.382 ± 0.23
0.287TrpIle: 0.287 ± 0.153
0.382TrpLys: 0.382 ± 0.214
1.147TrpLeu: 1.147 ± 0.259
0.669TrpMet: 0.669 ± 0.246
0.478TrpAsn: 0.478 ± 0.148
0.669TrpPro: 0.669 ± 0.264
0.86TrpGln: 0.86 ± 0.264
0.669TrpArg: 0.669 ± 0.251
1.625TrpSer: 1.625 ± 0.488
0.765TrpThr: 0.765 ± 0.224
0.478TrpVal: 0.478 ± 0.218
0.191TrpTrp: 0.191 ± 0.117
0.287TrpTyr: 0.287 ± 0.187
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.625TyrAla: 1.625 ± 0.496
0.478TyrCys: 0.478 ± 0.218
2.867TyrAsp: 2.867 ± 0.569
0.956TyrGlu: 0.956 ± 0.294
2.294TyrPhe: 2.294 ± 0.466
1.911TyrGly: 1.911 ± 0.318
1.434TyrHis: 1.434 ± 0.34
0.765TyrIle: 0.765 ± 0.277
1.338TyrLys: 1.338 ± 0.474
3.536TyrLeu: 3.536 ± 0.561
1.338TyrMet: 1.338 ± 0.333
1.051TyrAsn: 1.051 ± 0.428
1.529TyrPro: 1.529 ± 0.43
1.911TyrGln: 1.911 ± 0.44
2.103TyrArg: 2.103 ± 0.36
2.485TyrSer: 2.485 ± 0.591
2.676TyrThr: 2.676 ± 0.475
1.911TyrVal: 1.911 ± 0.423
0.287TyrTrp: 0.287 ± 0.135
0.669TyrTyr: 0.669 ± 0.257
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 34 proteins (10464 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski