Amino acid dipepetide frequency for Tilletiaria anomala (strain ATCC 24038 / CBS 436.72 / UBC 951)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.636AlaAla: 15.636 ± 0.141	1.225AlaCys: 1.225 ± 0.02	5.348AlaAsp: 5.348 ± 0.044	5.882AlaGlu: 5.882 ± 0.054	3.356AlaPhe: 3.356 ± 0.039	8.315AlaGly: 8.315 ± 0.062	2.591AlaHis: 2.591 ± 0.034	4.09AlaIle: 4.09 ± 0.039	4.622AlaLys: 4.622 ± 0.045	9.494AlaLeu: 9.494 ± 0.063	2.162AlaMet: 2.162 ± 0.022	3.308AlaAsn: 3.308 ± 0.029	6.359AlaPro: 6.359 ± 0.065	4.767AlaGln: 4.767 ± 0.047	6.612AlaArg: 6.612 ± 0.048	11.534AlaSer: 11.534 ± 0.095	6.276AlaThr: 6.276 ± 0.053	5.925AlaVal: 5.925 ± 0.048	1.184AlaTrp: 1.184 ± 0.024	2.147AlaTyr: 2.147 ± 0.028	0.0AlaXaa: 0.0 ± 0.0
Cys	1.126CysAla: 1.126 ± 0.018	0.22CysCys: 0.22 ± 0.008	0.577CysAsp: 0.577 ± 0.013	0.554CysGlu: 0.554 ± 0.012	0.462CysPhe: 0.462 ± 0.013	0.865CysGly: 0.865 ± 0.018	0.279CysHis: 0.279 ± 0.01	0.616CysIle: 0.616 ± 0.015	0.527CysLys: 0.527 ± 0.013	1.092CysLeu: 1.092 ± 0.023	0.257CysMet: 0.257 ± 0.009	0.399CysAsn: 0.399 ± 0.011	0.574CysPro: 0.574 ± 0.013	0.375CysGln: 0.375 ± 0.011	0.721CysArg: 0.721 ± 0.015	1.06CysSer: 1.06 ± 0.018	0.727CysThr: 0.727 ± 0.016	0.742CysVal: 0.742 ± 0.015	0.16CysTrp: 0.16 ± 0.007	0.283CysTyr: 0.283 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.351AspAla: 6.351 ± 0.049	0.534AspCys: 0.534 ± 0.012	4.043AspAsp: 4.043 ± 0.055	4.387AspGlu: 4.387 ± 0.051	1.733AspPhe: 1.733 ± 0.027	4.404AspGly: 4.404 ± 0.045	1.138AspHis: 1.138 ± 0.02	2.248AspIle: 2.248 ± 0.028	1.987AspLys: 1.987 ± 0.03	4.518AspLeu: 4.518 ± 0.045	1.111AspMet: 1.111 ± 0.015	1.386AspAsn: 1.386 ± 0.022	2.959AspPro: 2.959 ± 0.03	1.688AspGln: 1.688 ± 0.019	2.859AspArg: 2.859 ± 0.037	4.023AspSer: 4.023 ± 0.042	2.6AspThr: 2.6 ± 0.029	3.602AspVal: 3.602 ± 0.033	0.735AspTrp: 0.735 ± 0.014	1.129AspTyr: 1.129 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	6.106GluAla: 6.106 ± 0.051	0.568GluCys: 0.568 ± 0.012	3.919GluAsp: 3.919 ± 0.045	5.219GluGlu: 5.219 ± 0.067	1.396GluPhe: 1.396 ± 0.02	4.002GluGly: 4.002 ± 0.036	1.483GluHis: 1.483 ± 0.021	2.197GluIle: 2.197 ± 0.026	2.925GluLys: 2.925 ± 0.035	5.083GluLeu: 5.083 ± 0.046	1.321GluMet: 1.321 ± 0.021	1.665GluAsn: 1.665 ± 0.024	2.351GluPro: 2.351 ± 0.029	2.862GluGln: 2.862 ± 0.032	4.321GluArg: 4.321 ± 0.045	3.874GluSer: 3.874 ± 0.038	2.686GluThr: 2.686 ± 0.028	3.129GluVal: 3.129 ± 0.032	0.717GluTrp: 0.717 ± 0.015	1.237GluTyr: 1.237 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.252PheAla: 3.252 ± 0.029	0.459PheCys: 0.459 ± 0.013	2.036PheAsp: 2.036 ± 0.027	1.831PheGlu: 1.831 ± 0.024	1.32PhePhe: 1.32 ± 0.026	2.645PheGly: 2.645 ± 0.039	0.747PheHis: 0.747 ± 0.016	1.366PheIle: 1.366 ± 0.019	1.294PheLys: 1.294 ± 0.021	2.92PheLeu: 2.92 ± 0.037	0.608PheMet: 0.608 ± 0.013	1.103PheAsn: 1.103 ± 0.02	1.625PhePro: 1.625 ± 0.024	1.097PheGln: 1.097 ± 0.019	1.695PheArg: 1.695 ± 0.024	2.921PheSer: 2.921 ± 0.032	1.678PheThr: 1.678 ± 0.024	2.13PheVal: 2.13 ± 0.026	0.48PheTrp: 0.48 ± 0.012	0.82PheTyr: 0.82 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	7.926GlyAla: 7.926 ± 0.074	0.813GlyCys: 0.813 ± 0.016	3.764GlyAsp: 3.764 ± 0.037	3.735GlyGlu: 3.735 ± 0.038	2.379GlyPhe: 2.379 ± 0.028	7.344GlyGly: 7.344 ± 0.091	1.842GlyHis: 1.842 ± 0.025	3.126GlyIle: 3.126 ± 0.033	3.799GlyLys: 3.799 ± 0.039	5.861GlyLeu: 5.861 ± 0.046	1.625GlyMet: 1.625 ± 0.029	2.429GlyAsn: 2.429 ± 0.027	3.559GlyPro: 3.559 ± 0.037	2.827GlyGln: 2.827 ± 0.032	4.662GlyArg: 4.662 ± 0.044	7.709GlySer: 7.709 ± 0.059	4.332GlyThr: 4.332 ± 0.039	4.222GlyVal: 4.222 ± 0.033	0.994GlyTrp: 0.994 ± 0.018	1.654GlyTyr: 1.654 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.795HisAla: 2.795 ± 0.033	0.327HisCys: 0.327 ± 0.009	1.271HisAsp: 1.271 ± 0.021	1.303HisGlu: 1.303 ± 0.019	0.858HisPhe: 0.858 ± 0.015	1.901HisGly: 1.901 ± 0.027	0.943HisHis: 0.943 ± 0.025	1.103HisIle: 1.103 ± 0.017	0.86HisLys: 0.86 ± 0.017	2.379HisLeu: 2.379 ± 0.028	0.508HisMet: 0.508 ± 0.011	0.694HisAsn: 0.694 ± 0.013	1.694HisPro: 1.694 ± 0.025	1.093HisGln: 1.093 ± 0.023	1.66HisArg: 1.66 ± 0.021	2.196HisSer: 2.196 ± 0.026	1.343HisThr: 1.343 ± 0.02	1.589HisVal: 1.589 ± 0.022	0.294HisTrp: 0.294 ± 0.01	0.564HisTyr: 0.564 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.281IleAla: 4.281 ± 0.038	0.635IleCys: 0.635 ± 0.016	2.414IleAsp: 2.414 ± 0.031	2.422IleGlu: 2.422 ± 0.032	1.573IlePhe: 1.573 ± 0.025	2.912IleGly: 2.912 ± 0.034	0.942IleHis: 0.942 ± 0.018	1.901IleIle: 1.901 ± 0.026	1.862IleLys: 1.862 ± 0.025	3.595IleLeu: 3.595 ± 0.041	0.774IleMet: 0.774 ± 0.014	1.394IleAsn: 1.394 ± 0.02	2.296IlePro: 2.296 ± 0.03	1.477IleGln: 1.477 ± 0.025	2.384IleArg: 2.384 ± 0.028	3.623IleSer: 3.623 ± 0.036	2.169IleThr: 2.169 ± 0.023	2.716IleVal: 2.716 ± 0.03	0.52IleTrp: 0.52 ± 0.013	1.0IleTyr: 1.0 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.865LysAla: 4.865 ± 0.045	0.441LysCys: 0.441 ± 0.012	2.463LysAsp: 2.463 ± 0.033	3.082LysGlu: 3.082 ± 0.035	1.053LysPhe: 1.053 ± 0.019	3.304LysGly: 3.304 ± 0.037	1.107LysHis: 1.107 ± 0.021	1.639LysIle: 1.639 ± 0.026	2.667LysLys: 2.667 ± 0.042	3.78LysLeu: 3.78 ± 0.035	0.91LysMet: 0.91 ± 0.015	1.292LysAsn: 1.292 ± 0.02	2.226LysPro: 2.226 ± 0.029	1.975LysGln: 1.975 ± 0.028	3.55LysArg: 3.55 ± 0.036	3.178LysSer: 3.178 ± 0.035	2.149LysThr: 2.149 ± 0.026	2.636LysVal: 2.636 ± 0.031	0.499LysTrp: 0.499 ± 0.012	0.957LysTyr: 0.957 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	9.213LeuAla: 9.213 ± 0.068	1.209LeuCys: 1.209 ± 0.021	4.745LeuAsp: 4.745 ± 0.041	4.971LeuGlu: 4.971 ± 0.044	2.987LeuPhe: 2.987 ± 0.034	5.855LeuGly: 5.855 ± 0.049	2.471LeuHis: 2.471 ± 0.029	3.429LeuIle: 3.429 ± 0.039	3.737LeuLys: 3.737 ± 0.044	8.941LeuLeu: 8.941 ± 0.075	1.645LeuMet: 1.645 ± 0.022	2.705LeuAsn: 2.705 ± 0.031	5.929LeuPro: 5.929 ± 0.046	4.301LeuGln: 4.301 ± 0.037	6.202LeuArg: 6.202 ± 0.047	8.074LeuSer: 8.074 ± 0.056	4.495LeuThr: 4.495 ± 0.044	5.042LeuVal: 5.042 ± 0.044	1.012LeuTrp: 1.012 ± 0.023	1.918LeuTyr: 1.918 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.032MetAla: 2.032 ± 0.022	0.234MetCys: 0.234 ± 0.009	1.115MetAsp: 1.115 ± 0.02	1.053MetGlu: 1.053 ± 0.016	0.547MetPhe: 0.547 ± 0.012	1.345MetGly: 1.345 ± 0.021	0.569MetHis: 0.569 ± 0.013	0.768MetIle: 0.768 ± 0.015	0.761MetLys: 0.761 ± 0.015	2.031MetLeu: 2.031 ± 0.021	0.501MetMet: 0.501 ± 0.013	0.618MetAsn: 0.618 ± 0.013	1.326MetPro: 1.326 ± 0.021	1.079MetGln: 1.079 ± 0.019	1.483MetArg: 1.483 ± 0.02	1.897MetSer: 1.897 ± 0.024	1.163MetThr: 1.163 ± 0.02	1.083MetVal: 1.083 ± 0.018	0.213MetTrp: 0.213 ± 0.007	0.417MetTyr: 0.417 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.607AsnAla: 3.607 ± 0.036	0.332AsnCys: 0.332 ± 0.011	1.654AsnAsp: 1.654 ± 0.023	1.733AsnGlu: 1.733 ± 0.024	1.038AsnPhe: 1.038 ± 0.019	2.891AsnGly: 2.891 ± 0.035	0.633AsnHis: 0.633 ± 0.015	1.417AsnIle: 1.417 ± 0.024	1.288AsnLys: 1.288 ± 0.021	2.629AsnLeu: 2.629 ± 0.033	0.671AsnMet: 0.671 ± 0.014	1.071AsnAsn: 1.071 ± 0.023	1.796AsnPro: 1.796 ± 0.022	0.98AsnGln: 0.98 ± 0.019	1.657AsnArg: 1.657 ± 0.022	2.638AsnSer: 2.638 ± 0.03	1.743AsnThr: 1.743 ± 0.024	2.131AsnVal: 2.131 ± 0.025	0.361AsnTrp: 0.361 ± 0.01	0.685AsnTyr: 0.685 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	6.515ProAla: 6.515 ± 0.064	0.555ProCys: 0.555 ± 0.013	2.679ProAsp: 2.679 ± 0.029	2.892ProGlu: 2.892 ± 0.027	1.978ProPhe: 1.978 ± 0.025	4.025ProGly: 4.025 ± 0.045	1.495ProHis: 1.495 ± 0.024	2.203ProIle: 2.203 ± 0.026	2.145ProLys: 2.145 ± 0.027	5.044ProLeu: 5.044 ± 0.042	1.04ProMet: 1.04 ± 0.018	1.764ProAsn: 1.764 ± 0.021	5.321ProPro: 5.321 ± 0.081	2.401ProGln: 2.401 ± 0.031	3.441ProArg: 3.441 ± 0.036	7.203ProSer: 7.203 ± 0.072	3.657ProThr: 3.657 ± 0.034	3.266ProVal: 3.266 ± 0.035	0.623ProTrp: 0.623 ± 0.015	1.235ProTyr: 1.235 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	4.617GlnAla: 4.617 ± 0.04	0.424GlnCys: 0.424 ± 0.013	1.992GlnAsp: 1.992 ± 0.021	2.454GlnGlu: 2.454 ± 0.031	1.005GlnPhe: 1.005 ± 0.017	2.894GlnGly: 2.894 ± 0.031	1.523GlnHis: 1.523 ± 0.027	1.593GlnIle: 1.593 ± 0.019	1.729GlnLys: 1.729 ± 0.025	3.882GlnLeu: 3.882 ± 0.037	0.921GlnMet: 0.921 ± 0.016	1.22GlnAsn: 1.22 ± 0.02	2.637GlnPro: 2.637 ± 0.041	4.032GlnGln: 4.032 ± 0.094	3.303GlnArg: 3.303 ± 0.037	3.275GlnSer: 3.275 ± 0.036	2.132GlnThr: 2.132 ± 0.027	2.347GlnVal: 2.347 ± 0.031	0.455GlnTrp: 0.455 ± 0.011	0.887GlnTyr: 0.887 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	6.307ArgAla: 6.307 ± 0.052	0.787ArgCys: 0.787 ± 0.017	3.204ArgAsp: 3.204 ± 0.032	3.811ArgGlu: 3.811 ± 0.036	2.092ArgPhe: 2.092 ± 0.027	4.128ArgGly: 4.128 ± 0.043	1.652ArgHis: 1.652 ± 0.023	2.803ArgIle: 2.803 ± 0.03	3.557ArgLys: 3.557 ± 0.038	5.755ArgLeu: 5.755 ± 0.053	1.419ArgMet: 1.419 ± 0.019	2.076ArgAsn: 2.076 ± 0.028	3.548ArgPro: 3.548 ± 0.038	2.971ArgGln: 2.971 ± 0.034	5.742ArgArg: 5.742 ± 0.062	5.98ArgSer: 5.98 ± 0.058	3.484ArgThr: 3.484 ± 0.035	3.396ArgVal: 3.396 ± 0.031	0.867ArgTrp: 0.867 ± 0.016	1.446ArgTyr: 1.446 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	10.81SerAla: 10.81 ± 0.088	0.934SerCys: 0.934 ± 0.018	4.383SerAsp: 4.383 ± 0.044	4.114SerGlu: 4.114 ± 0.037	3.061SerPhe: 3.061 ± 0.034	7.238SerGly: 7.238 ± 0.053	2.227SerHis: 2.227 ± 0.026	3.959SerIle: 3.959 ± 0.033	3.93SerLys: 3.93 ± 0.04	7.953SerLeu: 7.953 ± 0.053	1.862SerMet: 1.862 ± 0.028	3.095SerAsn: 3.095 ± 0.029	5.998SerPro: 5.998 ± 0.069	3.44SerGln: 3.44 ± 0.04	5.604SerArg: 5.604 ± 0.054	13.118SerSer: 13.118 ± 0.151	6.304SerThr: 6.304 ± 0.052	5.013SerVal: 5.013 ± 0.043	0.944SerTrp: 0.944 ± 0.02	1.805SerTyr: 1.805 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	6.206ThrAla: 6.206 ± 0.051	0.685ThrCys: 0.685 ± 0.015	2.46ThrAsp: 2.46 ± 0.026	2.457ThrGlu: 2.457 ± 0.025	1.969ThrPhe: 1.969 ± 0.028	4.155ThrGly: 4.155 ± 0.042	1.296ThrHis: 1.296 ± 0.018	2.374ThrIle: 2.374 ± 0.032	2.094ThrLys: 2.094 ± 0.028	5.206ThrLeu: 5.206 ± 0.044	1.059ThrMet: 1.059 ± 0.017	1.669ThrAsn: 1.669 ± 0.025	4.004ThrPro: 4.004 ± 0.049	1.976ThrGln: 1.976 ± 0.024	3.212ThrArg: 3.212 ± 0.031	6.011ThrSer: 6.011 ± 0.056	3.447ThrThr: 3.447 ± 0.034	3.177ThrVal: 3.177 ± 0.033	0.696ThrTrp: 0.696 ± 0.014	1.203ThrTyr: 1.203 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.998ValAla: 5.998 ± 0.045	0.754ValCys: 0.754 ± 0.018	3.353ValAsp: 3.353 ± 0.034	3.348ValGlu: 3.348 ± 0.039	1.952ValPhe: 1.952 ± 0.025	3.968ValGly: 3.968 ± 0.037	1.532ValHis: 1.532 ± 0.019	2.472ValIle: 2.472 ± 0.033	2.558ValLys: 2.558 ± 0.032	5.469ValLeu: 5.469 ± 0.049	1.144ValMet: 1.144 ± 0.021	1.839ValAsn: 1.839 ± 0.026	3.604ValPro: 3.604 ± 0.031	2.626ValGln: 2.626 ± 0.029	3.7ValArg: 3.7 ± 0.033	4.735ValSer: 4.735 ± 0.034	3.047ValThr: 3.047 ± 0.029	3.64ValVal: 3.64 ± 0.036	0.715ValTrp: 0.715 ± 0.016	1.308ValTyr: 1.308 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.025TrpAla: 1.025 ± 0.019	0.181TrpCys: 0.181 ± 0.008	0.711TrpAsp: 0.711 ± 0.017	0.626TrpGlu: 0.626 ± 0.014	0.38TrpPhe: 0.38 ± 0.012	0.725TrpGly: 0.725 ± 0.014	0.337TrpHis: 0.337 ± 0.01	0.541TrpIle: 0.541 ± 0.013	0.603TrpLys: 0.603 ± 0.013	1.185TrpLeu: 1.185 ± 0.022	0.269TrpMet: 0.269 ± 0.009	0.458TrpAsn: 0.458 ± 0.012	0.578TrpPro: 0.578 ± 0.016	0.558TrpGln: 0.558 ± 0.015	0.9TrpArg: 0.9 ± 0.018	1.017TrpSer: 1.017 ± 0.018	0.734TrpThr: 0.734 ± 0.017	0.626TrpVal: 0.626 ± 0.012	0.215TrpTrp: 0.215 ± 0.009	0.299TrpTyr: 0.299 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.164TyrAla: 2.164 ± 0.026	0.302TyrCys: 0.302 ± 0.01	1.305TyrAsp: 1.305 ± 0.022	1.19TyrGlu: 1.19 ± 0.021	0.888TyrPhe: 0.888 ± 0.019	1.685TyrGly: 1.685 ± 0.023	0.569TyrHis: 0.569 ± 0.012	1.048TyrIle: 1.048 ± 0.018	0.829TyrLys: 0.829 ± 0.018	2.062TyrLeu: 2.062 ± 0.031	0.428TyrMet: 0.428 ± 0.012	0.772TyrAsn: 0.772 ± 0.017	1.096TyrPro: 1.096 ± 0.018	0.799TyrGln: 0.799 ± 0.014	1.318TyrArg: 1.318 ± 0.021	1.724TyrSer: 1.724 ± 0.022	1.186TyrThr: 1.186 ± 0.021	1.348TyrVal: 1.348 ± 0.023	0.282TyrTrp: 0.282 ± 0.01	0.609TyrTyr: 0.609 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6806 proteins (3543731 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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