Amino acid dipepetide frequency for fungal sp. No.11243

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.654AlaAla: 10.654 ± 0.069	1.188AlaCys: 1.188 ± 0.017	4.891AlaAsp: 4.891 ± 0.035	5.25AlaGlu: 5.25 ± 0.041	3.272AlaPhe: 3.272 ± 0.031	6.413AlaGly: 6.413 ± 0.044	1.989AlaHis: 1.989 ± 0.023	4.299AlaIle: 4.299 ± 0.037	4.172AlaLys: 4.172 ± 0.035	8.269AlaLeu: 8.269 ± 0.047	2.13AlaMet: 2.13 ± 0.022	3.031AlaAsn: 3.031 ± 0.03	5.02AlaPro: 5.02 ± 0.047	3.729AlaGln: 3.729 ± 0.03	5.686AlaArg: 5.686 ± 0.038	8.054AlaSer: 8.054 ± 0.057	5.784AlaThr: 5.784 ± 0.039	5.902AlaVal: 5.902 ± 0.044	1.226AlaTrp: 1.226 ± 0.021	2.142AlaTyr: 2.142 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	1.084CysAla: 1.084 ± 0.018	0.257CysCys: 0.257 ± 0.009	0.656CysAsp: 0.656 ± 0.013	0.572CysGlu: 0.572 ± 0.012	0.542CysPhe: 0.542 ± 0.012	0.986CysGly: 0.986 ± 0.017	0.337CysHis: 0.337 ± 0.011	0.684CysIle: 0.684 ± 0.014	0.51CysLys: 0.51 ± 0.011	1.284CysLeu: 1.284 ± 0.017	0.279CysMet: 0.279 ± 0.009	0.431CysAsn: 0.431 ± 0.011	0.678CysPro: 0.678 ± 0.015	0.42CysGln: 0.42 ± 0.011	0.828CysArg: 0.828 ± 0.014	0.966CysSer: 0.966 ± 0.018	0.742CysThr: 0.742 ± 0.015	0.823CysVal: 0.823 ± 0.014	0.193CysTrp: 0.193 ± 0.006	0.344CysTyr: 0.344 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.261AspAla: 5.261 ± 0.037	0.651AspCys: 0.651 ± 0.014	4.371AspAsp: 4.371 ± 0.045	4.487AspGlu: 4.487 ± 0.043	2.234AspPhe: 2.234 ± 0.022	4.211AspGly: 4.211 ± 0.035	1.316AspHis: 1.316 ± 0.018	2.776AspIle: 2.776 ± 0.027	2.443AspLys: 2.443 ± 0.027	5.137AspLeu: 5.137 ± 0.045	1.386AspMet: 1.386 ± 0.019	1.753AspAsn: 1.753 ± 0.022	3.163AspPro: 3.163 ± 0.026	1.977AspGln: 1.977 ± 0.023	3.403AspArg: 3.403 ± 0.035	4.269AspSer: 4.269 ± 0.033	3.051AspThr: 3.051 ± 0.026	3.807AspVal: 3.807 ± 0.035	0.889AspTrp: 0.889 ± 0.015	1.523AspTyr: 1.523 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.274GluAla: 5.274 ± 0.036	0.571GluCys: 0.571 ± 0.013	4.114GluAsp: 4.114 ± 0.046	4.846GluGlu: 4.846 ± 0.054	1.703GluPhe: 1.703 ± 0.022	3.632GluGly: 3.632 ± 0.03	1.473GluHis: 1.473 ± 0.021	2.692GluIle: 2.692 ± 0.03	3.256GluLys: 3.256 ± 0.039	4.902GluLeu: 4.902 ± 0.039	1.438GluMet: 1.438 ± 0.019	1.839GluAsn: 1.839 ± 0.022	2.427GluPro: 2.427 ± 0.027	2.535GluGln: 2.535 ± 0.029	4.046GluArg: 4.046 ± 0.038	4.07GluSer: 4.07 ± 0.038	3.236GluThr: 3.236 ± 0.028	3.459GluVal: 3.459 ± 0.033	0.839GluTrp: 0.839 ± 0.015	1.489GluTyr: 1.489 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.273PheAla: 3.273 ± 0.027	0.57PheCys: 0.57 ± 0.013	2.339PheAsp: 2.339 ± 0.024	2.04PheGlu: 2.04 ± 0.027	1.529PhePhe: 1.529 ± 0.025	2.764PheGly: 2.764 ± 0.034	0.858PheHis: 0.858 ± 0.015	1.579PheIle: 1.579 ± 0.022	1.4PheLys: 1.4 ± 0.018	3.27PheLeu: 3.27 ± 0.033	0.745PheMet: 0.745 ± 0.014	1.297PheAsn: 1.297 ± 0.019	1.769PhePro: 1.769 ± 0.023	1.254PheGln: 1.254 ± 0.018	1.894PheArg: 1.894 ± 0.02	2.89PheSer: 2.89 ± 0.027	2.048PheThr: 2.048 ± 0.027	2.45PheVal: 2.45 ± 0.026	0.61PheTrp: 0.61 ± 0.014	1.007PheTyr: 1.007 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.681GlyAla: 5.681 ± 0.049	0.91GlyCys: 0.91 ± 0.016	3.653GlyAsp: 3.653 ± 0.03	3.523GlyGlu: 3.523 ± 0.034	2.717GlyPhe: 2.717 ± 0.031	5.965GlyGly: 5.965 ± 0.063	1.757GlyHis: 1.757 ± 0.023	3.28GlyIle: 3.28 ± 0.033	3.401GlyLys: 3.401 ± 0.036	6.076GlyLeu: 6.076 ± 0.042	1.683GlyMet: 1.683 ± 0.019	2.368GlyAsn: 2.368 ± 0.029	3.391GlyPro: 3.391 ± 0.03	2.753GlyGln: 2.753 ± 0.033	4.516GlyArg: 4.516 ± 0.034	5.791GlySer: 5.791 ± 0.045	4.053GlyThr: 4.053 ± 0.04	4.388GlyVal: 4.388 ± 0.038	1.169GlyTrp: 1.169 ± 0.017	2.087GlyTyr: 2.087 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	2.133HisAla: 2.133 ± 0.024	0.354HisCys: 0.354 ± 0.011	1.478HisAsp: 1.478 ± 0.019	1.387HisGlu: 1.387 ± 0.021	0.964HisPhe: 0.964 ± 0.016	1.829HisGly: 1.829 ± 0.023	0.894HisHis: 0.894 ± 0.02	1.166HisIle: 1.166 ± 0.017	0.965HisLys: 0.965 ± 0.016	2.263HisLeu: 2.263 ± 0.024	0.538HisMet: 0.538 ± 0.013	0.832HisAsn: 0.832 ± 0.016	1.563HisPro: 1.563 ± 0.022	0.97HisGln: 0.97 ± 0.018	1.617HisArg: 1.617 ± 0.022	1.959HisSer: 1.959 ± 0.026	1.318HisThr: 1.318 ± 0.019	1.532HisVal: 1.532 ± 0.019	0.337HisTrp: 0.337 ± 0.009	0.643HisTyr: 0.643 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.338IleAla: 4.338 ± 0.036	0.679IleCys: 0.679 ± 0.015	2.863IleAsp: 2.863 ± 0.025	2.698IleGlu: 2.698 ± 0.03	1.763IlePhe: 1.763 ± 0.023	3.125IleGly: 3.125 ± 0.03	1.115IleHis: 1.115 ± 0.016	2.207IleIle: 2.207 ± 0.028	2.075IleLys: 2.075 ± 0.027	4.093IleLeu: 4.093 ± 0.04	0.977IleMet: 0.977 ± 0.016	1.661IleAsn: 1.661 ± 0.02	2.788IlePro: 2.788 ± 0.028	1.65IleGln: 1.65 ± 0.023	2.739IleArg: 2.739 ± 0.027	3.698IleSer: 3.698 ± 0.03	2.728IleThr: 2.728 ± 0.031	3.041IleVal: 3.041 ± 0.031	0.682IleTrp: 0.682 ± 0.015	1.272IleTyr: 1.272 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.285LysAla: 4.285 ± 0.041	0.471LysCys: 0.471 ± 0.01	2.785LysAsp: 2.785 ± 0.03	2.938LysGlu: 2.938 ± 0.038	1.309LysPhe: 1.309 ± 0.021	2.867LysGly: 2.867 ± 0.031	1.151LysHis: 1.151 ± 0.018	2.093LysIle: 2.093 ± 0.026	3.077LysLys: 3.077 ± 0.056	3.774LysLeu: 3.774 ± 0.032	1.009LysMet: 1.009 ± 0.017	1.453LysAsn: 1.453 ± 0.019	2.523LysPro: 2.523 ± 0.031	1.886LysGln: 1.886 ± 0.022	3.524LysArg: 3.524 ± 0.036	3.576LysSer: 3.576 ± 0.033	2.834LysThr: 2.834 ± 0.026	2.766LysVal: 2.766 ± 0.029	0.636LysTrp: 0.636 ± 0.013	1.226LysTyr: 1.226 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	8.313LeuAla: 8.313 ± 0.055	1.235LeuCys: 1.235 ± 0.016	5.297LeuAsp: 5.297 ± 0.041	5.095LeuGlu: 5.095 ± 0.041	3.148LeuPhe: 3.148 ± 0.035	5.798LeuGly: 5.798 ± 0.043	2.292LeuHis: 2.292 ± 0.024	3.741LeuIle: 3.741 ± 0.035	3.898LeuLys: 3.898 ± 0.036	8.333LeuLeu: 8.333 ± 0.066	1.724LeuMet: 1.724 ± 0.022	2.883LeuAsn: 2.883 ± 0.026	5.415LeuPro: 5.415 ± 0.037	3.784LeuGln: 3.784 ± 0.039	5.982LeuArg: 5.982 ± 0.047	7.428LeuSer: 7.428 ± 0.043	4.869LeuThr: 4.869 ± 0.035	5.587LeuVal: 5.587 ± 0.05	1.171LeuTrp: 1.171 ± 0.018	2.246LeuTyr: 2.246 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.353MetAla: 2.353 ± 0.025	0.249MetCys: 0.249 ± 0.007	1.314MetAsp: 1.314 ± 0.02	1.155MetGlu: 1.155 ± 0.018	0.73MetPhe: 0.73 ± 0.013	1.417MetGly: 1.417 ± 0.023	0.546MetHis: 0.546 ± 0.011	0.973MetIle: 0.973 ± 0.017	0.95MetLys: 0.95 ± 0.018	1.997MetLeu: 1.997 ± 0.024	0.561MetMet: 0.561 ± 0.012	0.745MetAsn: 0.745 ± 0.014	1.338MetPro: 1.338 ± 0.021	0.987MetGln: 0.987 ± 0.017	1.38MetArg: 1.38 ± 0.017	1.965MetSer: 1.965 ± 0.024	1.438MetThr: 1.438 ± 0.022	1.317MetVal: 1.317 ± 0.017	0.253MetTrp: 0.253 ± 0.008	0.528MetTyr: 0.528 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.27AsnAla: 3.27 ± 0.028	0.399AsnCys: 0.399 ± 0.011	1.892AsnAsp: 1.892 ± 0.02	1.795AsnGlu: 1.795 ± 0.023	1.256AsnPhe: 1.256 ± 0.021	2.874AsnGly: 2.874 ± 0.032	0.808AsnHis: 0.808 ± 0.013	1.78AsnIle: 1.78 ± 0.022	1.424AsnLys: 1.424 ± 0.02	2.958AsnLeu: 2.958 ± 0.03	0.792AsnMet: 0.792 ± 0.015	1.272AsnAsn: 1.272 ± 0.017	2.143AsnPro: 2.143 ± 0.024	1.211AsnGln: 1.211 ± 0.018	1.814AsnArg: 1.814 ± 0.018	2.526AsnSer: 2.526 ± 0.025	2.04AsnThr: 2.04 ± 0.025	2.199AsnVal: 2.199 ± 0.023	0.457AsnTrp: 0.457 ± 0.01	0.916AsnTyr: 0.916 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.58ProAla: 5.58 ± 0.047	0.572ProCys: 0.572 ± 0.013	3.136ProAsp: 3.136 ± 0.027	3.298ProGlu: 3.298 ± 0.028	1.999ProPhe: 1.999 ± 0.022	3.902ProGly: 3.902 ± 0.037	1.373ProHis: 1.373 ± 0.021	2.387ProIle: 2.387 ± 0.023	2.427ProLys: 2.427 ± 0.03	4.678ProLeu: 4.678 ± 0.037	1.092ProMet: 1.092 ± 0.017	1.928ProAsn: 1.928 ± 0.026	4.818ProPro: 4.818 ± 0.069	2.356ProGln: 2.356 ± 0.029	3.525ProArg: 3.525 ± 0.037	6.018ProSer: 6.018 ± 0.048	3.906ProThr: 3.906 ± 0.04	3.493ProVal: 3.493 ± 0.032	0.72ProTrp: 0.72 ± 0.014	1.38ProTyr: 1.38 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.659GlnAla: 3.659 ± 0.031	0.478GlnCys: 0.478 ± 0.011	2.148GlnAsp: 2.148 ± 0.026	2.18GlnGlu: 2.18 ± 0.021	1.185GlnPhe: 1.185 ± 0.018	2.446GlnGly: 2.446 ± 0.033	1.185GlnHis: 1.185 ± 0.019	1.876GlnIle: 1.876 ± 0.022	1.905GlnLys: 1.905 ± 0.023	3.365GlnLeu: 3.365 ± 0.031	0.946GlnMet: 0.946 ± 0.019	1.491GlnAsn: 1.491 ± 0.022	2.418GlnPro: 2.418 ± 0.026	2.598GlnGln: 2.598 ± 0.052	2.885GlnArg: 2.885 ± 0.03	3.443GlnSer: 3.443 ± 0.034	2.463GlnThr: 2.463 ± 0.023	2.167GlnVal: 2.167 ± 0.024	0.544GlnTrp: 0.544 ± 0.011	1.105GlnTyr: 1.105 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.379ArgAla: 5.379 ± 0.041	0.817ArgCys: 0.817 ± 0.016	3.578ArgAsp: 3.578 ± 0.031	3.75ArgGlu: 3.75 ± 0.034	2.152ArgPhe: 2.152 ± 0.023	3.996ArgGly: 3.996 ± 0.04	1.75ArgHis: 1.75 ± 0.02	2.937ArgIle: 2.937 ± 0.027	3.456ArgLys: 3.456 ± 0.039	5.868ArgLeu: 5.868 ± 0.043	1.49ArgMet: 1.49 ± 0.019	2.142ArgAsn: 2.142 ± 0.023	3.801ArgPro: 3.801 ± 0.037	2.817ArgGln: 2.817 ± 0.028	5.709ArgArg: 5.709 ± 0.053	5.266ArgSer: 5.266 ± 0.055	3.664ArgThr: 3.664 ± 0.03	3.482ArgVal: 3.482 ± 0.033	0.945ArgTrp: 0.945 ± 0.017	1.621ArgTyr: 1.621 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	7.688SerAla: 7.688 ± 0.059	0.942SerCys: 0.942 ± 0.016	4.448SerAsp: 4.448 ± 0.043	4.027SerGlu: 4.027 ± 0.041	2.92SerPhe: 2.92 ± 0.028	5.896SerGly: 5.896 ± 0.051	2.014SerHis: 2.014 ± 0.027	3.965SerIle: 3.965 ± 0.03	3.672SerLys: 3.672 ± 0.034	7.253SerLeu: 7.253 ± 0.055	1.81SerMet: 1.81 ± 0.022	2.914SerAsn: 2.914 ± 0.028	5.639SerPro: 5.639 ± 0.056	3.29SerGln: 3.29 ± 0.032	5.35SerArg: 5.35 ± 0.046	9.329SerSer: 9.329 ± 0.089	6.013SerThr: 6.013 ± 0.055	4.759SerVal: 4.759 ± 0.039	1.075SerTrp: 1.075 ± 0.018	1.99SerTyr: 1.99 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.866ThrAla: 5.866 ± 0.041	0.782ThrCys: 0.782 ± 0.015	2.977ThrAsp: 2.977 ± 0.028	2.922ThrGlu: 2.922 ± 0.031	2.192ThrPhe: 2.192 ± 0.026	4.186ThrGly: 4.186 ± 0.038	1.366ThrHis: 1.366 ± 0.02	3.028ThrIle: 3.028 ± 0.028	2.58ThrLys: 2.58 ± 0.025	5.247ThrLeu: 5.247 ± 0.044	1.271ThrMet: 1.271 ± 0.018	2.074ThrAsn: 2.074 ± 0.021	4.155ThrPro: 4.155 ± 0.042	2.162ThrGln: 2.162 ± 0.025	3.378ThrArg: 3.378 ± 0.03	5.873ThrSer: 5.873 ± 0.052	5.317ThrThr: 5.317 ± 0.125	3.842ThrVal: 3.842 ± 0.037	0.825ThrTrp: 0.825 ± 0.016	1.529ThrTyr: 1.529 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.7ValAla: 5.7 ± 0.042	0.89ValCys: 0.89 ± 0.015	3.727ValAsp: 3.727 ± 0.035	3.731ValGlu: 3.731 ± 0.032	2.373ValPhe: 2.373 ± 0.029	3.984ValGly: 3.984 ± 0.036	1.449ValHis: 1.449 ± 0.018	2.77ValIle: 2.77 ± 0.03	2.88ValLys: 2.88 ± 0.029	5.706ValLeu: 5.706 ± 0.047	1.37ValMet: 1.37 ± 0.018	2.114ValAsn: 2.114 ± 0.023	3.593ValPro: 3.593 ± 0.031	2.481ValGln: 2.481 ± 0.026	3.773ValArg: 3.773 ± 0.028	4.791ValSer: 4.791 ± 0.038	3.532ValThr: 3.532 ± 0.036	4.549ValVal: 4.549 ± 0.054	0.865ValTrp: 0.865 ± 0.015	1.634ValTyr: 1.634 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.144TrpAla: 1.144 ± 0.017	0.189TrpCys: 0.189 ± 0.007	0.836TrpAsp: 0.836 ± 0.016	0.753TrpGlu: 0.753 ± 0.016	0.505TrpPhe: 0.505 ± 0.013	0.841TrpGly: 0.841 ± 0.015	0.367TrpHis: 0.367 ± 0.01	0.713TrpIle: 0.713 ± 0.013	0.691TrpLys: 0.691 ± 0.012	1.335TrpLeu: 1.335 ± 0.022	0.362TrpMet: 0.362 ± 0.009	0.562TrpAsn: 0.562 ± 0.012	0.615TrpPro: 0.615 ± 0.014	0.601TrpGln: 0.601 ± 0.014	1.025TrpArg: 1.025 ± 0.018	1.12TrpSer: 1.12 ± 0.018	0.985TrpThr: 0.985 ± 0.018	0.797TrpVal: 0.797 ± 0.016	0.255TrpTrp: 0.255 ± 0.009	0.402TrpTyr: 0.402 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.166TyrAla: 2.166 ± 0.024	0.41TyrCys: 0.41 ± 0.012	1.605TyrAsp: 1.605 ± 0.02	1.395TyrGlu: 1.395 ± 0.021	1.093TyrPhe: 1.093 ± 0.018	2.031TyrGly: 2.031 ± 0.025	0.701TyrHis: 0.701 ± 0.014	1.247TyrIle: 1.247 ± 0.019	1.004TyrLys: 1.004 ± 0.016	2.429TyrLeu: 2.429 ± 0.028	0.593TyrMet: 0.593 ± 0.012	1.036TyrAsn: 1.036 ± 0.018	1.33TyrPro: 1.33 ± 0.02	1.024TyrGln: 1.024 ± 0.016	1.549TyrArg: 1.549 ± 0.023	1.962TyrSer: 1.962 ± 0.025	1.551TyrThr: 1.551 ± 0.018	1.549TyrVal: 1.549 ± 0.02	0.408TyrTrp: 0.408 ± 0.01	0.858TyrTyr: 0.858 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9692 proteins (4222938 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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