Amino acid dipepetide frequency for Candidatus Sedimenticola endophacoides

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.779AlaAla: 11.779 ± 0.246
1.305AlaCys: 1.305 ± 0.081
5.401AlaAsp: 5.401 ± 0.133
6.673AlaGlu: 6.673 ± 0.159
3.431AlaPhe: 3.431 ± 0.111
9.284AlaGly: 9.284 ± 0.182
2.252AlaHis: 2.252 ± 0.082
5.076AlaIle: 5.076 ± 0.128
2.647AlaLys: 2.647 ± 0.088
12.629AlaLeu: 12.629 ± 0.275
2.953AlaMet: 2.953 ± 0.111
2.571AlaAsn: 2.571 ± 0.091
4.202AlaPro: 4.202 ± 0.122
3.578AlaGln: 3.578 ± 0.095
8.52AlaArg: 8.52 ± 0.189
4.684AlaSer: 4.684 ± 0.127
4.268AlaThr: 4.268 ± 0.121
6.916AlaVal: 6.916 ± 0.148
1.279AlaTrp: 1.279 ± 0.071
2.498AlaTyr: 2.498 ± 0.09
0.0AlaXaa: 0.0 ± 0.0
Cys
1.123CysAla: 1.123 ± 0.07
0.14CysCys: 0.14 ± 0.026
0.654CysAsp: 0.654 ± 0.046
0.608CysGlu: 0.608 ± 0.044
0.339CysPhe: 0.339 ± 0.03
1.116CysGly: 1.116 ± 0.066
0.389CysHis: 0.389 ± 0.05
0.438CysIle: 0.438 ± 0.035
0.223CysLys: 0.223 ± 0.029
0.953CysLeu: 0.953 ± 0.049
0.226CysMet: 0.226 ± 0.029
0.279CysAsn: 0.279 ± 0.025
0.724CysPro: 0.724 ± 0.053
0.342CysGln: 0.342 ± 0.035
0.9CysArg: 0.9 ± 0.057
0.531CysSer: 0.531 ± 0.045
0.515CysThr: 0.515 ± 0.044
0.711CysVal: 0.711 ± 0.05
0.113CysTrp: 0.113 ± 0.018
0.246CysTyr: 0.246 ± 0.03
0.0CysXaa: 0.0 ± 0.0
Asp
5.331AspAla: 5.331 ± 0.128
0.581AspCys: 0.581 ± 0.044
3.0AspAsp: 3.0 ± 0.122
3.893AspGlu: 3.893 ± 0.127
1.95AspPhe: 1.95 ± 0.082
4.74AspGly: 4.74 ± 0.119
1.352AspHis: 1.352 ± 0.07
3.232AspIle: 3.232 ± 0.113
1.538AspLys: 1.538 ± 0.081
6.261AspLeu: 6.261 ± 0.142
1.372AspMet: 1.372 ± 0.076
1.405AspAsn: 1.405 ± 0.063
3.239AspPro: 3.239 ± 0.109
2.099AspGln: 2.099 ± 0.084
3.684AspArg: 3.684 ± 0.115
2.574AspSer: 2.574 ± 0.095
2.558AspThr: 2.558 ± 0.091
3.106AspVal: 3.106 ± 0.106
0.734AspTrp: 0.734 ± 0.05
1.727AspTyr: 1.727 ± 0.082
0.0AspXaa: 0.0 ± 0.0
Glu
7.371GluAla: 7.371 ± 0.157
0.541GluCys: 0.541 ± 0.044
2.332GluAsp: 2.332 ± 0.09
4.733GluGlu: 4.733 ± 0.142
2.089GluPhe: 2.089 ± 0.078
5.122GluGly: 5.122 ± 0.138
1.814GluHis: 1.814 ± 0.074
4.072GluIle: 4.072 ± 0.111
2.275GluLys: 2.275 ± 0.086
7.391GluLeu: 7.391 ± 0.162
2.069GluMet: 2.069 ± 0.089
1.797GluAsn: 1.797 ± 0.072
2.893GluPro: 2.893 ± 0.117
3.953GluGln: 3.953 ± 0.126
7.188GluArg: 7.188 ± 0.2
3.265GluSer: 3.265 ± 0.103
3.176GluThr: 3.176 ± 0.101
4.929GluVal: 4.929 ± 0.14
0.847GluTrp: 0.847 ± 0.054
1.541GluTyr: 1.541 ± 0.067
0.0GluXaa: 0.0 ± 0.0
Phe
3.388PheAla: 3.388 ± 0.101
0.399PheCys: 0.399 ± 0.042
2.584PheAsp: 2.584 ± 0.093
2.348PheGlu: 2.348 ± 0.081
1.475PhePhe: 1.475 ± 0.084
2.96PheGly: 2.96 ± 0.09
0.857PheHis: 0.857 ± 0.05
1.893PheIle: 1.893 ± 0.094
1.133PheLys: 1.133 ± 0.064
3.385PheLeu: 3.385 ± 0.125
0.87PheMet: 0.87 ± 0.055
1.189PheAsn: 1.189 ± 0.069
1.491PhePro: 1.491 ± 0.069
1.189PheGln: 1.189 ± 0.059
2.116PheArg: 2.116 ± 0.083
2.601PheSer: 2.601 ± 0.101
1.943PheThr: 1.943 ± 0.087
2.322PheVal: 2.322 ± 0.092
0.438PheTrp: 0.438 ± 0.037
0.993PheTyr: 0.993 ± 0.057
0.0PheXaa: 0.0 ± 0.0
Gly
8.381GlyAla: 8.381 ± 0.177
1.119GlyCys: 1.119 ± 0.063
4.607GlyAsp: 4.607 ± 0.128
6.55GlyGlu: 6.55 ± 0.176
3.455GlyPhe: 3.455 ± 0.126
7.444GlyGly: 7.444 ± 0.206
2.053GlyHis: 2.053 ± 0.091
4.73GlyIle: 4.73 ± 0.124
2.973GlyLys: 2.973 ± 0.105
9.298GlyLeu: 9.298 ± 0.178
2.588GlyMet: 2.588 ± 0.1
2.242GlyAsn: 2.242 ± 0.091
2.614GlyPro: 2.614 ± 0.096
2.873GlyGln: 2.873 ± 0.104
6.494GlyArg: 6.494 ± 0.155
4.239GlySer: 4.239 ± 0.124
3.92GlyThr: 3.92 ± 0.112
6.75GlyVal: 6.75 ± 0.156
1.116GlyTrp: 1.116 ± 0.068
2.657GlyTyr: 2.657 ± 0.1
0.0GlyXaa: 0.0 ± 0.0
His
2.275HisAla: 2.275 ± 0.088
0.372HisCys: 0.372 ± 0.037
1.226HisAsp: 1.226 ± 0.071
1.369HisGlu: 1.369 ± 0.072
1.046HisPhe: 1.046 ± 0.057
2.265HisGly: 2.265 ± 0.09
0.834HisHis: 0.834 ± 0.06
1.229HisIle: 1.229 ± 0.058
0.634HisLys: 0.634 ± 0.047
2.601HisLeu: 2.601 ± 0.105
0.581HisMet: 0.581 ± 0.044
0.708HisAsn: 0.708 ± 0.055
1.761HisPro: 1.761 ± 0.077
1.023HisGln: 1.023 ± 0.058
1.737HisArg: 1.737 ± 0.074
1.163HisSer: 1.163 ± 0.062
1.183HisThr: 1.183 ± 0.05
1.149HisVal: 1.149 ± 0.073
0.409HisTrp: 0.409 ± 0.036
0.774HisTyr: 0.774 ± 0.053
0.0HisXaa: 0.0 ± 0.0
Ile
5.388IleAla: 5.388 ± 0.152
0.492IleCys: 0.492 ± 0.047
4.049IleAsp: 4.049 ± 0.124
4.179IleGlu: 4.179 ± 0.129
1.674IlePhe: 1.674 ± 0.078
5.175IleGly: 5.175 ± 0.142
1.332IleHis: 1.332 ± 0.068
2.322IleIle: 2.322 ± 0.096
1.827IleLys: 1.827 ± 0.087
5.009IleLeu: 5.009 ± 0.148
1.023IleMet: 1.023 ± 0.066
1.907IleAsn: 1.907 ± 0.082
2.671IlePro: 2.671 ± 0.092
1.644IleGln: 1.644 ± 0.068
3.707IleArg: 3.707 ± 0.104
2.97IleSer: 2.97 ± 0.103
3.029IleThr: 3.029 ± 0.092
3.139IleVal: 3.139 ± 0.108
0.462IleTrp: 0.462 ± 0.044
1.359IleTyr: 1.359 ± 0.075
0.0IleXaa: 0.0 ± 0.0
Lys
3.009LysAla: 3.009 ± 0.109
0.229LysCys: 0.229 ± 0.031
1.425LysAsp: 1.425 ± 0.082
2.026LysGlu: 2.026 ± 0.079
0.784LysPhe: 0.784 ± 0.051
2.531LysGly: 2.531 ± 0.102
0.638LysHis: 0.638 ± 0.047
1.641LysIle: 1.641 ± 0.079
1.212LysLys: 1.212 ± 0.076
2.807LysLeu: 2.807 ± 0.089
0.737LysMet: 0.737 ± 0.052
0.827LysAsn: 0.827 ± 0.058
1.428LysPro: 1.428 ± 0.063
1.289LysGln: 1.289 ± 0.071
2.611LysArg: 2.611 ± 0.096
1.814LysSer: 1.814 ± 0.07
1.445LysThr: 1.445 ± 0.078
2.339LysVal: 2.339 ± 0.095
0.289LysTrp: 0.289 ± 0.037
0.668LysTyr: 0.668 ± 0.048
0.0LysXaa: 0.0 ± 0.0
Leu
12.031LeuAla: 12.031 ± 0.248
1.056LeuCys: 1.056 ± 0.054
6.431LeuAsp: 6.431 ± 0.166
7.889LeuGlu: 7.889 ± 0.196
4.342LeuPhe: 4.342 ± 0.131
9.51LeuGly: 9.51 ± 0.181
2.711LeuHis: 2.711 ± 0.081
5.783LeuIle: 5.783 ± 0.175
3.421LeuLys: 3.421 ± 0.124
13.516LeuLeu: 13.516 ± 0.284
2.422LeuMet: 2.422 ± 0.09
3.149LeuAsn: 3.149 ± 0.104
5.654LeuPro: 5.654 ± 0.135
3.671LeuGln: 3.671 ± 0.112
8.57LeuArg: 8.57 ± 0.194
6.378LeuSer: 6.378 ± 0.157
5.208LeuThr: 5.208 ± 0.142
7.75LeuVal: 7.75 ± 0.206
1.043LeuTrp: 1.043 ± 0.071
2.661LeuTyr: 2.661 ± 0.081
0.0LeuXaa: 0.0 ± 0.0
Met
2.8MetAla: 2.8 ± 0.083
0.206MetCys: 0.206 ± 0.023
1.438MetAsp: 1.438 ± 0.067
1.721MetGlu: 1.721 ± 0.076
0.698MetPhe: 0.698 ± 0.054
2.023MetGly: 2.023 ± 0.081
0.535MetHis: 0.535 ± 0.043
1.375MetIle: 1.375 ± 0.071
1.006MetLys: 1.006 ± 0.055
2.833MetLeu: 2.833 ± 0.105
0.628MetMet: 0.628 ± 0.053
0.804MetAsn: 0.804 ± 0.049
1.362MetPro: 1.362 ± 0.067
1.129MetGln: 1.129 ± 0.061
1.84MetArg: 1.84 ± 0.078
1.654MetSer: 1.654 ± 0.08
1.179MetThr: 1.179 ± 0.062
1.754MetVal: 1.754 ± 0.088
0.193MetTrp: 0.193 ± 0.024
0.415MetTyr: 0.415 ± 0.037
0.0MetXaa: 0.0 ± 0.0
Asn
2.667AsnAla: 2.667 ± 0.092
0.355AsnCys: 0.355 ± 0.034
1.319AsnAsp: 1.319 ± 0.068
1.518AsnGlu: 1.518 ± 0.062
0.95AsnPhe: 0.95 ± 0.064
2.269AsnGly: 2.269 ± 0.092
0.688AsnHis: 0.688 ± 0.052
1.844AsnIle: 1.844 ± 0.078
0.741AsnLys: 0.741 ± 0.048
2.903AsnLeu: 2.903 ± 0.096
0.615AsnMet: 0.615 ± 0.043
0.854AsnAsn: 0.854 ± 0.056
1.877AsnPro: 1.877 ± 0.081
1.103AsnGln: 1.103 ± 0.051
2.189AsnArg: 2.189 ± 0.088
1.382AsnSer: 1.382 ± 0.077
1.315AsnThr: 1.315 ± 0.077
1.648AsnVal: 1.648 ± 0.074
0.365AsnTrp: 0.365 ± 0.036
0.834AsnTyr: 0.834 ± 0.053
0.0AsnXaa: 0.0 ± 0.0
Pro
4.826ProAla: 4.826 ± 0.149
0.402ProCys: 0.402 ± 0.036
2.89ProAsp: 2.89 ± 0.107
4.053ProGlu: 4.053 ± 0.129
1.681ProPhe: 1.681 ± 0.063
4.896ProGly: 4.896 ± 0.137
1.013ProHis: 1.013 ± 0.056
2.016ProIle: 2.016 ± 0.086
1.193ProLys: 1.193 ± 0.064
5.418ProLeu: 5.418 ± 0.139
1.252ProMet: 1.252 ± 0.069
1.193ProAsn: 1.193 ± 0.068
2.325ProPro: 2.325 ± 0.094
1.827ProGln: 1.827 ± 0.078
3.196ProArg: 3.196 ± 0.113
2.136ProSer: 2.136 ± 0.076
1.807ProThr: 1.807 ± 0.084
3.71ProVal: 3.71 ± 0.105
0.684ProTrp: 0.684 ± 0.047
1.375ProTyr: 1.375 ± 0.073
0.0ProXaa: 0.0 ± 0.0
Gln
4.521GlnAla: 4.521 ± 0.118
0.339GlnCys: 0.339 ± 0.032
1.485GlnAsp: 1.485 ± 0.07
2.541GlnGlu: 2.541 ± 0.095
1.163GlnPhe: 1.163 ± 0.07
3.421GlnGly: 3.421 ± 0.109
0.84GlnHis: 0.84 ± 0.054
2.05GlnIle: 2.05 ± 0.094
1.026GlnLys: 1.026 ± 0.067
4.026GlnLeu: 4.026 ± 0.109
0.953GlnMet: 0.953 ± 0.058
0.884GlnAsn: 0.884 ± 0.062
1.751GlnPro: 1.751 ± 0.083
1.691GlnGln: 1.691 ± 0.092
3.322GlnArg: 3.322 ± 0.106
1.844GlnSer: 1.844 ± 0.073
1.591GlnThr: 1.591 ± 0.072
2.82GlnVal: 2.82 ± 0.11
0.565GlnTrp: 0.565 ± 0.044
0.757GlnTyr: 0.757 ± 0.053
0.0GlnXaa: 0.0 ± 0.0
Arg
6.756ArgAla: 6.756 ± 0.153
0.777ArgCys: 0.777 ± 0.059
4.222ArgAsp: 4.222 ± 0.116
6.295ArgGlu: 6.295 ± 0.16
3.156ArgPhe: 3.156 ± 0.104
5.348ArgGly: 5.348 ± 0.13
2.285ArgHis: 2.285 ± 0.098
4.67ArgIle: 4.67 ± 0.142
2.322ArgLys: 2.322 ± 0.08
9.729ArgLeu: 9.729 ± 0.236
2.172ArgMet: 2.172 ± 0.082
1.927ArgAsn: 1.927 ± 0.079
3.345ArgPro: 3.345 ± 0.106
3.518ArgGln: 3.518 ± 0.118
6.62ArgArg: 6.62 ± 0.17
3.295ArgSer: 3.295 ± 0.102
2.887ArgThr: 2.887 ± 0.099
5.454ArgVal: 5.454 ± 0.13
1.106ArgTrp: 1.106 ± 0.065
2.435ArgTyr: 2.435 ± 0.084
0.0ArgXaa: 0.0 ± 0.0
Ser
5.288SerAla: 5.288 ± 0.132
0.588SerCys: 0.588 ± 0.044
2.943SerAsp: 2.943 ± 0.101
3.136SerGlu: 3.136 ± 0.116
1.797SerPhe: 1.797 ± 0.082
5.547SerGly: 5.547 ± 0.134
1.189SerHis: 1.189 ± 0.063
2.697SerIle: 2.697 ± 0.095
1.332SerLys: 1.332 ± 0.068
5.717SerLeu: 5.717 ± 0.138
1.352SerMet: 1.352 ± 0.075
1.335SerAsn: 1.335 ± 0.078
2.681SerPro: 2.681 ± 0.096
1.648SerGln: 1.648 ± 0.073
3.857SerArg: 3.857 ± 0.123
2.73SerSer: 2.73 ± 0.103
2.362SerThr: 2.362 ± 0.1
3.528SerVal: 3.528 ± 0.116
0.578SerTrp: 0.578 ± 0.047
1.362SerTyr: 1.362 ± 0.073
0.0SerXaa: 0.0 ± 0.0
Thr
4.295ThrAla: 4.295 ± 0.121
0.445ThrCys: 0.445 ± 0.041
2.226ThrAsp: 2.226 ± 0.088
2.515ThrGlu: 2.515 ± 0.104
1.694ThrPhe: 1.694 ± 0.072
4.444ThrGly: 4.444 ± 0.108
1.196ThrHis: 1.196 ± 0.067
2.495ThrIle: 2.495 ± 0.102
1.066ThrLys: 1.066 ± 0.066
6.331ThrLeu: 6.331 ± 0.139
0.947ThrMet: 0.947 ± 0.061
1.133ThrAsn: 1.133 ± 0.057
3.039ThrPro: 3.039 ± 0.094
1.375ThrGln: 1.375 ± 0.065
3.398ThrArg: 3.398 ± 0.11
2.275ThrSer: 2.275 ± 0.094
2.202ThrThr: 2.202 ± 0.087
3.229ThrVal: 3.229 ± 0.121
0.478ThrTrp: 0.478 ± 0.039
0.933ThrTyr: 0.933 ± 0.056
0.0ThrXaa: 0.0 ± 0.0
Val
7.334ValAla: 7.334 ± 0.167
0.767ValCys: 0.767 ± 0.056
4.122ValAsp: 4.122 ± 0.123
5.172ValGlu: 5.172 ± 0.128
2.358ValPhe: 2.358 ± 0.087
5.086ValGly: 5.086 ± 0.139
1.359ValHis: 1.359 ± 0.071
3.96ValIle: 3.96 ± 0.126
2.169ValLys: 2.169 ± 0.09
7.58ValLeu: 7.58 ± 0.171
1.973ValMet: 1.973 ± 0.085
2.113ValAsn: 2.113 ± 0.083
2.933ValPro: 2.933 ± 0.101
2.05ValGln: 2.05 ± 0.093
4.846ValArg: 4.846 ± 0.134
4.033ValSer: 4.033 ± 0.137
3.458ValThr: 3.458 ± 0.121
5.703ValVal: 5.703 ± 0.153
0.668ValTrp: 0.668 ± 0.045
1.628ValTyr: 1.628 ± 0.077
0.0ValXaa: 0.0 ± 0.0
Trp
0.884TrpAla: 0.884 ± 0.052
0.179TrpCys: 0.179 ± 0.023
0.615TrpAsp: 0.615 ± 0.041
0.774TrpGlu: 0.774 ± 0.051
0.485TrpPhe: 0.485 ± 0.04
0.811TrpGly: 0.811 ± 0.047
0.302TrpHis: 0.302 ± 0.031
0.664TrpIle: 0.664 ± 0.046
0.326TrpLys: 0.326 ± 0.031
1.664TrpLeu: 1.664 ± 0.075
0.335TrpMet: 0.335 ± 0.038
0.332TrpAsn: 0.332 ± 0.032
0.548TrpPro: 0.548 ± 0.043
0.452TrpGln: 0.452 ± 0.043
1.006TrpArg: 1.006 ± 0.058
0.694TrpSer: 0.694 ± 0.051
0.365TrpThr: 0.365 ± 0.038
0.884TrpVal: 0.884 ± 0.053
0.196TrpTrp: 0.196 ± 0.026
0.335TrpTyr: 0.335 ± 0.038
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.498TyrAla: 2.498 ± 0.086
0.276TyrCys: 0.276 ± 0.034
1.408TyrAsp: 1.408 ± 0.077
1.408TyrGlu: 1.408 ± 0.06
1.01TyrPhe: 1.01 ± 0.061
2.109TyrGly: 2.109 ± 0.093
0.701TyrHis: 0.701 ± 0.049
1.169TyrIle: 1.169 ± 0.07
0.688TyrLys: 0.688 ± 0.048
3.142TyrLeu: 3.142 ± 0.104
0.522TyrMet: 0.522 ± 0.035
0.787TyrAsn: 0.787 ± 0.056
1.355TyrPro: 1.355 ± 0.075
1.136TyrGln: 1.136 ± 0.061
2.518TyrArg: 2.518 ± 0.103
1.405TyrSer: 1.405 ± 0.07
1.305TyrThr: 1.305 ± 0.073
1.472TyrVal: 1.472 ± 0.063
0.289TyrTrp: 0.289 ± 0.032
0.811TyrTyr: 0.811 ± 0.058
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1190 proteins (301048 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski