Amino acid dipepetide frequency for Grapevine endophyte alphaendornavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.974AlaAla: 3.974 ± 0.0
1.987AlaCys: 1.987 ± 0.0
4.968AlaAsp: 4.968 ± 0.0
3.229AlaGlu: 3.229 ± 0.0
1.739AlaPhe: 1.739 ± 0.0
2.981AlaGly: 2.981 ± 0.0
2.484AlaHis: 2.484 ± 0.0
5.464AlaIle: 5.464 ± 0.0
3.974AlaLys: 3.974 ± 0.0
7.203AlaLeu: 7.203 ± 0.0
1.739AlaMet: 1.739 ± 0.0
4.471AlaAsn: 4.471 ± 0.0
1.242AlaPro: 1.242 ± 0.0
3.229AlaGln: 3.229 ± 0.0
2.732AlaArg: 2.732 ± 0.0
4.223AlaSer: 4.223 ± 0.0
3.974AlaThr: 3.974 ± 0.0
5.961AlaVal: 5.961 ± 0.0
0.745AlaTrp: 0.745 ± 0.0
2.732AlaTyr: 2.732 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.739CysAla: 1.739 ± 0.0
1.242CysCys: 1.242 ± 0.0
1.739CysAsp: 1.739 ± 0.0
0.497CysGlu: 0.497 ± 0.0
0.745CysPhe: 0.745 ± 0.0
1.242CysGly: 1.242 ± 0.0
0.745CysHis: 0.745 ± 0.0
0.994CysIle: 0.994 ± 0.0
0.994CysLys: 0.994 ± 0.0
1.739CysLeu: 1.739 ± 0.0
0.497CysMet: 0.497 ± 0.0
2.484CysAsn: 2.484 ± 0.0
0.745CysPro: 0.745 ± 0.0
0.497CysGln: 0.497 ± 0.0
0.745CysArg: 0.745 ± 0.0
0.745CysSer: 0.745 ± 0.0
0.497CysThr: 0.497 ± 0.0
1.987CysVal: 1.987 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.497CysTyr: 0.497 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.961AspAla: 5.961 ± 0.0
0.745AspCys: 0.745 ± 0.0
4.719AspAsp: 4.719 ± 0.0
4.471AspGlu: 4.471 ± 0.0
1.242AspPhe: 1.242 ± 0.0
4.223AspGly: 4.223 ± 0.0
1.49AspHis: 1.49 ± 0.0
3.974AspIle: 3.974 ± 0.0
4.223AspLys: 4.223 ± 0.0
3.477AspLeu: 3.477 ± 0.0
2.235AspMet: 2.235 ± 0.0
3.477AspAsn: 3.477 ± 0.0
1.49AspPro: 1.49 ± 0.0
0.745AspGln: 0.745 ± 0.0
1.242AspArg: 1.242 ± 0.0
4.471AspSer: 4.471 ± 0.0
5.713AspThr: 5.713 ± 0.0
5.216AspVal: 5.216 ± 0.0
0.0AspTrp: 0.0 ± 0.0
1.987AspTyr: 1.987 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.223GluAla: 4.223 ± 0.0
0.745GluCys: 0.745 ± 0.0
1.49GluAsp: 1.49 ± 0.0
2.484GluGlu: 2.484 ± 0.0
2.235GluPhe: 2.235 ± 0.0
0.994GluGly: 0.994 ± 0.0
1.49GluHis: 1.49 ± 0.0
3.477GluIle: 3.477 ± 0.0
1.739GluLys: 1.739 ± 0.0
4.968GluLeu: 4.968 ± 0.0
1.739GluMet: 1.739 ± 0.0
1.49GluAsn: 1.49 ± 0.0
2.235GluPro: 2.235 ± 0.0
1.739GluGln: 1.739 ± 0.0
0.994GluArg: 0.994 ± 0.0
2.732GluSer: 2.732 ± 0.0
3.477GluThr: 3.477 ± 0.0
2.235GluVal: 2.235 ± 0.0
0.994GluTrp: 0.994 ± 0.0
1.49GluTyr: 1.49 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.719PheAla: 4.719 ± 0.0
0.497PheCys: 0.497 ± 0.0
3.229PheAsp: 3.229 ± 0.0
1.49PheGlu: 1.49 ± 0.0
0.994PhePhe: 0.994 ± 0.0
1.987PheGly: 1.987 ± 0.0
0.497PheHis: 0.497 ± 0.0
0.745PheIle: 0.745 ± 0.0
2.235PheLys: 2.235 ± 0.0
2.732PheLeu: 2.732 ± 0.0
1.49PheMet: 1.49 ± 0.0
2.981PheAsn: 2.981 ± 0.0
0.497PhePro: 0.497 ± 0.0
0.745PheGln: 0.745 ± 0.0
1.739PheArg: 1.739 ± 0.0
2.484PheSer: 2.484 ± 0.0
3.726PheThr: 3.726 ± 0.0
2.235PheVal: 2.235 ± 0.0
0.248PheTrp: 0.248 ± 0.0
0.994PheTyr: 0.994 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.974GlyAla: 3.974 ± 0.0
0.497GlyCys: 0.497 ± 0.0
4.968GlyAsp: 4.968 ± 0.0
1.242GlyGlu: 1.242 ± 0.0
1.49GlyPhe: 1.49 ± 0.0
1.739GlyGly: 1.739 ± 0.0
1.242GlyHis: 1.242 ± 0.0
3.726GlyIle: 3.726 ± 0.0
2.484GlyLys: 2.484 ± 0.0
2.981GlyLeu: 2.981 ± 0.0
1.242GlyMet: 1.242 ± 0.0
3.229GlyAsn: 3.229 ± 0.0
1.242GlyPro: 1.242 ± 0.0
1.49GlyGln: 1.49 ± 0.0
0.0GlyArg: 0.0 ± 0.0
3.229GlySer: 3.229 ± 0.0
4.471GlyThr: 4.471 ± 0.0
3.974GlyVal: 3.974 ± 0.0
0.497GlyTrp: 0.497 ± 0.0
1.987GlyTyr: 1.987 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.477HisAla: 3.477 ± 0.0
0.497HisCys: 0.497 ± 0.0
0.994HisAsp: 0.994 ± 0.0
0.745HisGlu: 0.745 ± 0.0
0.497HisPhe: 0.497 ± 0.0
3.974HisGly: 3.974 ± 0.0
1.739HisHis: 1.739 ± 0.0
2.732HisIle: 2.732 ± 0.0
0.745HisLys: 0.745 ± 0.0
3.477HisLeu: 3.477 ± 0.0
1.739HisMet: 1.739 ± 0.0
1.987HisAsn: 1.987 ± 0.0
1.49HisPro: 1.49 ± 0.0
1.49HisGln: 1.49 ± 0.0
0.745HisArg: 0.745 ± 0.0
2.981HisSer: 2.981 ± 0.0
2.981HisThr: 2.981 ± 0.0
1.49HisVal: 1.49 ± 0.0
0.745HisTrp: 0.745 ± 0.0
2.235HisTyr: 2.235 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.974IleAla: 3.974 ± 0.0
2.235IleCys: 2.235 ± 0.0
3.974IleAsp: 3.974 ± 0.0
3.477IleGlu: 3.477 ± 0.0
2.732IlePhe: 2.732 ± 0.0
2.981IleGly: 2.981 ± 0.0
1.739IleHis: 1.739 ± 0.0
3.229IleIle: 3.229 ± 0.0
2.732IleLys: 2.732 ± 0.0
5.713IleLeu: 5.713 ± 0.0
1.739IleMet: 1.739 ± 0.0
4.471IleAsn: 4.471 ± 0.0
4.719IlePro: 4.719 ± 0.0
1.242IleGln: 1.242 ± 0.0
4.223IleArg: 4.223 ± 0.0
4.968IleSer: 4.968 ± 0.0
6.955IleThr: 6.955 ± 0.0
5.713IleVal: 5.713 ± 0.0
0.248IleTrp: 0.248 ± 0.0
1.739IleTyr: 1.739 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.484LysAla: 2.484 ± 0.0
0.994LysCys: 0.994 ± 0.0
1.49LysAsp: 1.49 ± 0.0
1.49LysGlu: 1.49 ± 0.0
3.726LysPhe: 3.726 ± 0.0
2.235LysGly: 2.235 ± 0.0
2.235LysHis: 2.235 ± 0.0
1.987LysIle: 1.987 ± 0.0
0.994LysLys: 0.994 ± 0.0
6.21LysLeu: 6.21 ± 0.0
1.987LysMet: 1.987 ± 0.0
1.242LysAsn: 1.242 ± 0.0
2.981LysPro: 2.981 ± 0.0
3.229LysGln: 3.229 ± 0.0
2.484LysArg: 2.484 ± 0.0
3.477LysSer: 3.477 ± 0.0
3.974LysThr: 3.974 ± 0.0
3.477LysVal: 3.477 ± 0.0
1.49LysTrp: 1.49 ± 0.0
2.981LysTyr: 2.981 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.464LeuAla: 5.464 ± 0.0
0.497LeuCys: 0.497 ± 0.0
3.974LeuAsp: 3.974 ± 0.0
4.471LeuGlu: 4.471 ± 0.0
3.229LeuPhe: 3.229 ± 0.0
5.464LeuGly: 5.464 ± 0.0
2.981LeuHis: 2.981 ± 0.0
5.713LeuIle: 5.713 ± 0.0
3.229LeuLys: 3.229 ± 0.0
8.445LeuLeu: 8.445 ± 0.0
2.235LeuMet: 2.235 ± 0.0
6.458LeuAsn: 6.458 ± 0.0
4.719LeuPro: 4.719 ± 0.0
3.477LeuGln: 3.477 ± 0.0
4.471LeuArg: 4.471 ± 0.0
6.21LeuSer: 6.21 ± 0.0
7.7LeuThr: 7.7 ± 0.0
7.452LeuVal: 7.452 ± 0.0
0.497LeuTrp: 0.497 ± 0.0
3.974LeuTyr: 3.974 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.987MetAla: 1.987 ± 0.0
0.745MetCys: 0.745 ± 0.0
1.242MetAsp: 1.242 ± 0.0
1.739MetGlu: 1.739 ± 0.0
0.745MetPhe: 0.745 ± 0.0
0.745MetGly: 0.745 ± 0.0
1.49MetHis: 1.49 ± 0.0
1.987MetIle: 1.987 ± 0.0
0.745MetLys: 0.745 ± 0.0
4.471MetLeu: 4.471 ± 0.0
1.49MetMet: 1.49 ± 0.0
1.242MetAsn: 1.242 ± 0.0
1.739MetPro: 1.739 ± 0.0
1.987MetGln: 1.987 ± 0.0
0.994MetArg: 0.994 ± 0.0
2.981MetSer: 2.981 ± 0.0
2.484MetThr: 2.484 ± 0.0
0.745MetVal: 0.745 ± 0.0
0.497MetTrp: 0.497 ± 0.0
0.497MetTyr: 0.497 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.477AsnAla: 3.477 ± 0.0
1.242AsnCys: 1.242 ± 0.0
1.987AsnAsp: 1.987 ± 0.0
1.242AsnGlu: 1.242 ± 0.0
2.484AsnPhe: 2.484 ± 0.0
3.229AsnGly: 3.229 ± 0.0
1.49AsnHis: 1.49 ± 0.0
4.719AsnIle: 4.719 ± 0.0
1.987AsnLys: 1.987 ± 0.0
3.477AsnLeu: 3.477 ± 0.0
2.732AsnMet: 2.732 ± 0.0
3.477AsnAsn: 3.477 ± 0.0
1.987AsnPro: 1.987 ± 0.0
2.235AsnGln: 2.235 ± 0.0
4.223AsnArg: 4.223 ± 0.0
3.229AsnSer: 3.229 ± 0.0
6.21AsnThr: 6.21 ± 0.0
4.471AsnVal: 4.471 ± 0.0
0.497AsnTrp: 0.497 ± 0.0
2.981AsnTyr: 2.981 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.732ProAla: 2.732 ± 0.0
1.242ProCys: 1.242 ± 0.0
2.484ProAsp: 2.484 ± 0.0
2.235ProGlu: 2.235 ± 0.0
0.745ProPhe: 0.745 ± 0.0
0.994ProGly: 0.994 ± 0.0
1.242ProHis: 1.242 ± 0.0
4.223ProIle: 4.223 ± 0.0
3.477ProLys: 3.477 ± 0.0
4.471ProLeu: 4.471 ± 0.0
1.739ProMet: 1.739 ± 0.0
1.987ProAsn: 1.987 ± 0.0
1.49ProPro: 1.49 ± 0.0
1.49ProGln: 1.49 ± 0.0
1.242ProArg: 1.242 ± 0.0
1.987ProSer: 1.987 ± 0.0
4.719ProThr: 4.719 ± 0.0
4.471ProVal: 4.471 ± 0.0
0.497ProTrp: 0.497 ± 0.0
2.484ProTyr: 2.484 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.242GlnAla: 1.242 ± 0.0
0.497GlnCys: 0.497 ± 0.0
1.739GlnAsp: 1.739 ± 0.0
1.49GlnGlu: 1.49 ± 0.0
1.987GlnPhe: 1.987 ± 0.0
0.994GlnGly: 0.994 ± 0.0
1.242GlnHis: 1.242 ± 0.0
1.987GlnIle: 1.987 ± 0.0
0.745GlnLys: 0.745 ± 0.0
4.719GlnLeu: 4.719 ± 0.0
0.994GlnMet: 0.994 ± 0.0
0.994GlnAsn: 0.994 ± 0.0
3.974GlnPro: 3.974 ± 0.0
1.987GlnGln: 1.987 ± 0.0
1.987GlnArg: 1.987 ± 0.0
1.739GlnSer: 1.739 ± 0.0
3.229GlnThr: 3.229 ± 0.0
3.477GlnVal: 3.477 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.994GlnTyr: 0.994 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.229ArgAla: 3.229 ± 0.0
0.994ArgCys: 0.994 ± 0.0
1.987ArgAsp: 1.987 ± 0.0
0.497ArgGlu: 0.497 ± 0.0
1.242ArgPhe: 1.242 ± 0.0
1.739ArgGly: 1.739 ± 0.0
3.726ArgHis: 3.726 ± 0.0
3.974ArgIle: 3.974 ± 0.0
3.477ArgLys: 3.477 ± 0.0
5.713ArgLeu: 5.713 ± 0.0
1.49ArgMet: 1.49 ± 0.0
1.987ArgAsn: 1.987 ± 0.0
2.484ArgPro: 2.484 ± 0.0
1.739ArgGln: 1.739 ± 0.0
0.994ArgArg: 0.994 ± 0.0
4.471ArgSer: 4.471 ± 0.0
1.242ArgThr: 1.242 ± 0.0
1.739ArgVal: 1.739 ± 0.0
0.248ArgTrp: 0.248 ± 0.0
0.497ArgTyr: 0.497 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.719SerAla: 4.719 ± 0.0
0.994SerCys: 0.994 ± 0.0
4.968SerAsp: 4.968 ± 0.0
2.981SerGlu: 2.981 ± 0.0
2.484SerPhe: 2.484 ± 0.0
3.477SerGly: 3.477 ± 0.0
1.987SerHis: 1.987 ± 0.0
5.713SerIle: 5.713 ± 0.0
5.713SerLys: 5.713 ± 0.0
5.713SerLeu: 5.713 ± 0.0
2.235SerMet: 2.235 ± 0.0
3.974SerAsn: 3.974 ± 0.0
1.739SerPro: 1.739 ± 0.0
1.242SerGln: 1.242 ± 0.0
3.477SerArg: 3.477 ± 0.0
6.955SerSer: 6.955 ± 0.0
3.229SerThr: 3.229 ± 0.0
4.471SerVal: 4.471 ± 0.0
0.248SerTrp: 0.248 ± 0.0
3.229SerTyr: 3.229 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.471ThrAla: 4.471 ± 0.0
1.739ThrCys: 1.739 ± 0.0
5.216ThrAsp: 5.216 ± 0.0
3.726ThrGlu: 3.726 ± 0.0
2.981ThrPhe: 2.981 ± 0.0
2.235ThrGly: 2.235 ± 0.0
2.981ThrHis: 2.981 ± 0.0
5.464ThrIle: 5.464 ± 0.0
4.471ThrLys: 4.471 ± 0.0
6.21ThrLeu: 6.21 ± 0.0
1.987ThrMet: 1.987 ± 0.0
5.216ThrAsn: 5.216 ± 0.0
4.471ThrPro: 4.471 ± 0.0
2.235ThrGln: 2.235 ± 0.0
3.974ThrArg: 3.974 ± 0.0
5.464ThrSer: 5.464 ± 0.0
5.464ThrThr: 5.464 ± 0.0
4.719ThrVal: 4.719 ± 0.0
1.242ThrTrp: 1.242 ± 0.0
2.981ThrTyr: 2.981 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.223ValAla: 4.223 ± 0.0
1.242ValCys: 1.242 ± 0.0
5.961ValAsp: 5.961 ± 0.0
4.223ValGlu: 4.223 ± 0.0
2.484ValPhe: 2.484 ± 0.0
2.732ValGly: 2.732 ± 0.0
3.477ValHis: 3.477 ± 0.0
4.968ValIle: 4.968 ± 0.0
4.719ValLys: 4.719 ± 0.0
4.968ValLeu: 4.968 ± 0.0
0.497ValMet: 0.497 ± 0.0
3.229ValAsn: 3.229 ± 0.0
4.968ValPro: 4.968 ± 0.0
3.974ValGln: 3.974 ± 0.0
4.968ValArg: 4.968 ± 0.0
3.477ValSer: 3.477 ± 0.0
3.974ValThr: 3.974 ± 0.0
3.726ValVal: 3.726 ± 0.0
0.248ValTrp: 0.248 ± 0.0
1.739ValTyr: 1.739 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.745TrpAla: 0.745 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.745TrpAsp: 0.745 ± 0.0
0.745TrpGlu: 0.745 ± 0.0
0.745TrpPhe: 0.745 ± 0.0
0.248TrpGly: 0.248 ± 0.0
0.745TrpHis: 0.745 ± 0.0
0.248TrpIle: 0.248 ± 0.0
0.497TrpLys: 0.497 ± 0.0
0.745TrpLeu: 0.745 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.745TrpAsn: 0.745 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.248TrpGln: 0.248 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.242TrpSer: 1.242 ± 0.0
0.745TrpThr: 0.745 ± 0.0
0.497TrpVal: 0.497 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.248TrpTyr: 0.248 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.235TyrAla: 2.235 ± 0.0
1.739TyrCys: 1.739 ± 0.0
3.229TyrAsp: 3.229 ± 0.0
0.497TyrGlu: 0.497 ± 0.0
1.739TyrPhe: 1.739 ± 0.0
1.49TyrGly: 1.49 ± 0.0
1.739TyrHis: 1.739 ± 0.0
3.477TyrIle: 3.477 ± 0.0
1.987TyrLys: 1.987 ± 0.0
3.229TyrLeu: 3.229 ± 0.0
0.497TyrMet: 0.497 ± 0.0
2.235TyrAsn: 2.235 ± 0.0
1.739TyrPro: 1.739 ± 0.0
0.994TyrGln: 0.994 ± 0.0
2.235TyrArg: 2.235 ± 0.0
2.484TyrSer: 2.484 ± 0.0
2.484TyrThr: 2.484 ± 0.0
1.987TyrVal: 1.987 ± 0.0
0.248TyrTrp: 0.248 ± 0.0
1.739TyrTyr: 1.739 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (4027 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski