Amino acid dipepetide frequency for Beihai sobemo-like virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.699AlaAla: 10.699 ± 0.403
0.713AlaCys: 0.713 ± 0.315
9.272AlaAsp: 9.272 ± 0.249
4.993AlaGlu: 4.993 ± 0.359
2.853AlaPhe: 2.853 ± 0.022
7.133AlaGly: 7.133 ± 0.696
4.28AlaHis: 4.28 ± 0.608
4.28AlaIle: 4.28 ± 0.674
3.566AlaLys: 3.566 ± 2.271
10.699AlaLeu: 10.699 ± 1.685
2.14AlaMet: 2.14 ± 1.486
2.853AlaAsn: 2.853 ± 0.022
3.566AlaPro: 3.566 ± 0.293
1.427AlaGln: 1.427 ± 0.652
7.846AlaArg: 7.846 ± 2.183
4.28AlaSer: 4.28 ± 1.956
2.853AlaThr: 2.853 ± 1.26
8.559AlaVal: 8.559 ± 1.348
1.427AlaTrp: 1.427 ± 0.652
5.706AlaTyr: 5.706 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
4.28CysAla: 4.28 ± 0.608
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.427CysLys: 1.427 ± 0.652
2.14CysLeu: 2.14 ± 0.945
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.14CysPro: 2.14 ± 1.619
0.0CysGln: 0.0 ± 0.0
0.713CysArg: 0.713 ± 0.967
1.427CysSer: 1.427 ± 0.652
1.427CysThr: 1.427 ± 0.63
0.713CysVal: 0.713 ± 0.315
0.713CysTrp: 0.713 ± 0.967
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.993AspAla: 4.993 ± 1.641
0.713AspCys: 0.713 ± 0.315
2.853AspAsp: 2.853 ± 0.022
5.706AspGlu: 5.706 ± 2.52
5.706AspPhe: 5.706 ± 0.044
3.566AspGly: 3.566 ± 0.293
0.713AspHis: 0.713 ± 0.315
2.14AspIle: 2.14 ± 0.945
2.853AspLys: 2.853 ± 1.26
8.559AspLeu: 8.559 ± 1.348
0.0AspMet: 0.0 ± 0.0
2.14AspAsn: 2.14 ± 0.337
1.427AspPro: 1.427 ± 1.934
0.713AspGln: 0.713 ± 0.315
2.853AspArg: 2.853 ± 1.26
2.14AspSer: 2.14 ± 0.337
4.993AspThr: 4.993 ± 2.923
4.993AspVal: 4.993 ± 0.923
0.0AspTrp: 0.0 ± 0.0
1.427AspTyr: 1.427 ± 0.63
0.0AspXaa: 0.0 ± 0.0
Glu
5.706GluAla: 5.706 ± 1.238
0.0GluCys: 0.0 ± 0.0
2.853GluAsp: 2.853 ± 1.26
11.412GluGlu: 11.412 ± 5.04
0.713GluPhe: 0.713 ± 0.315
7.133GluGly: 7.133 ± 0.696
0.713GluHis: 0.713 ± 0.315
3.566GluIle: 3.566 ± 1.575
3.566GluLys: 3.566 ± 1.575
4.28GluLeu: 4.28 ± 1.89
0.0GluMet: 0.0 ± 0.0
0.713GluAsn: 0.713 ± 0.315
3.566GluPro: 3.566 ± 1.575
1.427GluGln: 1.427 ± 0.63
7.133GluArg: 7.133 ± 3.15
4.993GluSer: 4.993 ± 2.205
1.427GluThr: 1.427 ± 0.652
1.427GluVal: 1.427 ± 0.63
0.713GluTrp: 0.713 ± 0.967
2.853GluTyr: 2.853 ± 1.26
0.0GluXaa: 0.0 ± 0.0
Phe
1.427PheAla: 1.427 ± 1.934
0.713PheCys: 0.713 ± 0.967
2.14PheAsp: 2.14 ± 0.337
3.566PheGlu: 3.566 ± 0.293
0.0PhePhe: 0.0 ± 0.0
7.846PheGly: 7.846 ± 0.381
0.713PheHis: 0.713 ± 0.967
0.713PheIle: 0.713 ± 0.315
0.0PheLys: 0.0 ± 0.0
2.14PheLeu: 2.14 ± 0.945
2.14PheMet: 2.14 ± 0.945
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
2.853PheArg: 2.853 ± 1.26
1.427PheSer: 1.427 ± 0.63
1.427PheThr: 1.427 ± 0.652
1.427PheVal: 1.427 ± 0.652
0.0PheTrp: 0.0 ± 0.0
0.713PheTyr: 0.713 ± 0.967
0.0PheXaa: 0.0 ± 0.0
Gly
4.993GlyAla: 4.993 ± 1.641
2.14GlyCys: 2.14 ± 0.945
4.28GlyAsp: 4.28 ± 0.608
6.419GlyGlu: 6.419 ± 2.835
2.853GlyPhe: 2.853 ± 1.304
2.14GlyGly: 2.14 ± 0.337
4.28GlyHis: 4.28 ± 0.674
4.993GlyIle: 4.993 ± 1.641
2.853GlyLys: 2.853 ± 1.304
4.993GlyLeu: 4.993 ± 2.205
2.853GlyMet: 2.853 ± 1.304
4.28GlyAsn: 4.28 ± 1.956
2.14GlyPro: 2.14 ± 0.945
2.853GlyGln: 2.853 ± 0.022
4.28GlyArg: 4.28 ± 0.674
3.566GlySer: 3.566 ± 0.293
3.566GlyThr: 3.566 ± 0.989
9.986GlyVal: 9.986 ± 0.718
0.713GlyTrp: 0.713 ± 0.315
2.14GlyTyr: 2.14 ± 0.945
0.0GlyXaa: 0.0 ± 0.0
His
1.427HisAla: 1.427 ± 0.63
0.0HisCys: 0.0 ± 0.0
0.713HisAsp: 0.713 ± 0.315
0.713HisGlu: 0.713 ± 0.315
0.713HisPhe: 0.713 ± 0.315
2.853HisGly: 2.853 ± 0.022
0.0HisHis: 0.0 ± 0.0
2.14HisIle: 2.14 ± 0.945
1.427HisLys: 1.427 ± 0.63
4.993HisLeu: 4.993 ± 0.923
0.0HisMet: 0.0 ± 0.0
1.427HisAsn: 1.427 ± 0.63
3.566HisPro: 3.566 ± 0.989
0.0HisGln: 0.0 ± 0.0
0.713HisArg: 0.713 ± 0.315
2.853HisSer: 2.853 ± 1.26
2.14HisThr: 2.14 ± 0.337
2.853HisVal: 2.853 ± 1.26
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.566IleAla: 3.566 ± 0.293
0.0IleCys: 0.0 ± 0.0
4.28IleAsp: 4.28 ± 0.608
1.427IleGlu: 1.427 ± 0.63
1.427IlePhe: 1.427 ± 0.652
2.14IleGly: 2.14 ± 0.337
1.427IleHis: 1.427 ± 0.63
0.0IleIle: 0.0 ± 0.0
2.853IleLys: 2.853 ± 2.586
6.419IleLeu: 6.419 ± 1.553
1.427IleMet: 1.427 ± 0.63
1.427IleAsn: 1.427 ± 0.63
3.566IlePro: 3.566 ± 0.293
1.427IleGln: 1.427 ± 0.63
1.427IleArg: 1.427 ± 0.652
4.28IleSer: 4.28 ± 0.608
2.853IleThr: 2.853 ± 1.26
1.427IleVal: 1.427 ± 0.652
0.713IleTrp: 0.713 ± 0.315
0.713IleTyr: 0.713 ± 0.315
0.0IleXaa: 0.0 ± 0.0
Lys
9.272LysAla: 9.272 ± 0.249
0.0LysCys: 0.0 ± 0.0
6.419LysAsp: 6.419 ± 1.553
2.853LysGlu: 2.853 ± 1.26
0.713LysPhe: 0.713 ± 0.967
2.853LysGly: 2.853 ± 1.304
2.14LysHis: 2.14 ± 0.945
0.713LysIle: 0.713 ± 0.315
6.419LysLys: 6.419 ± 1.553
2.853LysLeu: 2.853 ± 0.022
2.14LysMet: 2.14 ± 0.945
1.427LysAsn: 1.427 ± 0.652
0.713LysPro: 0.713 ± 0.315
2.14LysGln: 2.14 ± 2.901
4.28LysArg: 4.28 ± 1.956
2.853LysSer: 2.853 ± 0.022
2.853LysThr: 2.853 ± 0.022
3.566LysVal: 3.566 ± 0.989
2.14LysTrp: 2.14 ± 0.337
2.853LysTyr: 2.853 ± 1.26
0.0LysXaa: 0.0 ± 0.0
Leu
7.846LeuAla: 7.846 ± 0.381
3.566LeuCys: 3.566 ± 0.989
5.706LeuAsp: 5.706 ± 0.044
6.419LeuGlu: 6.419 ± 2.835
2.853LeuPhe: 2.853 ± 0.022
4.28LeuGly: 4.28 ± 1.89
4.993LeuHis: 4.993 ± 2.205
6.419LeuIle: 6.419 ± 2.835
6.419LeuLys: 6.419 ± 1.553
6.419LeuLeu: 6.419 ± 0.271
1.427LeuMet: 1.427 ± 1.473
2.853LeuAsn: 2.853 ± 1.26
2.853LeuPro: 2.853 ± 1.304
3.566LeuGln: 3.566 ± 0.989
6.419LeuArg: 6.419 ± 0.271
4.993LeuSer: 4.993 ± 0.923
4.28LeuThr: 4.28 ± 0.674
8.559LeuVal: 8.559 ± 0.066
0.713LeuTrp: 0.713 ± 0.315
2.853LeuTyr: 2.853 ± 1.26
0.0LeuXaa: 0.0 ± 0.0
Met
2.853MetAla: 2.853 ± 1.26
0.713MetCys: 0.713 ± 0.967
0.713MetAsp: 0.713 ± 0.967
1.427MetGlu: 1.427 ± 0.652
0.0MetPhe: 0.0 ± 0.0
2.14MetGly: 2.14 ± 0.337
0.713MetHis: 0.713 ± 0.315
0.713MetIle: 0.713 ± 0.315
2.14MetLys: 2.14 ± 0.945
2.853MetLeu: 2.853 ± 0.022
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.14MetSer: 2.14 ± 0.337
0.713MetThr: 0.713 ± 0.967
1.427MetVal: 1.427 ± 1.934
1.427MetTrp: 1.427 ± 0.63
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.28AsnAla: 4.28 ± 0.674
0.713AsnCys: 0.713 ± 0.315
0.713AsnAsp: 0.713 ± 0.315
0.0AsnGlu: 0.0 ± 0.0
0.713AsnPhe: 0.713 ± 0.315
1.427AsnGly: 1.427 ± 0.63
1.427AsnHis: 1.427 ± 0.652
2.14AsnIle: 2.14 ± 0.337
1.427AsnLys: 1.427 ± 1.934
2.853AsnLeu: 2.853 ± 1.26
2.14AsnMet: 2.14 ± 0.337
2.14AsnAsn: 2.14 ± 0.337
1.427AsnPro: 1.427 ± 0.652
0.0AsnGln: 0.0 ± 0.0
3.566AsnArg: 3.566 ± 0.989
0.0AsnSer: 0.0 ± 0.0
4.28AsnThr: 4.28 ± 0.674
2.853AsnVal: 2.853 ± 1.26
0.713AsnTrp: 0.713 ± 0.315
0.713AsnTyr: 0.713 ± 0.315
0.0AsnXaa: 0.0 ± 0.0
Pro
4.28ProAla: 4.28 ± 1.956
0.0ProCys: 0.0 ± 0.0
0.713ProAsp: 0.713 ± 0.967
3.566ProGlu: 3.566 ± 1.575
0.713ProPhe: 0.713 ± 0.967
7.846ProGly: 7.846 ± 0.901
0.0ProHis: 0.0 ± 0.0
2.14ProIle: 2.14 ± 0.337
2.853ProLys: 2.853 ± 0.022
2.853ProLeu: 2.853 ± 0.022
0.713ProMet: 0.713 ± 0.315
0.713ProAsn: 0.713 ± 0.967
2.853ProPro: 2.853 ± 1.26
1.427ProGln: 1.427 ± 0.63
4.993ProArg: 4.993 ± 2.923
1.427ProSer: 1.427 ± 0.63
2.853ProThr: 2.853 ± 1.26
0.713ProVal: 0.713 ± 0.967
0.0ProTrp: 0.0 ± 0.0
1.427ProTyr: 1.427 ± 0.63
0.0ProXaa: 0.0 ± 0.0
Gln
2.14GlnAla: 2.14 ± 0.945
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.14GlnGlu: 2.14 ± 0.945
0.713GlnPhe: 0.713 ± 0.967
2.853GlnGly: 2.853 ± 1.304
0.713GlnHis: 0.713 ± 0.315
0.0GlnIle: 0.0 ± 0.0
2.14GlnLys: 2.14 ± 0.337
2.853GlnLeu: 2.853 ± 0.022
0.713GlnMet: 0.713 ± 0.315
2.14GlnAsn: 2.14 ± 0.945
2.14GlnPro: 2.14 ± 0.945
0.713GlnGln: 0.713 ± 0.315
0.0GlnArg: 0.0 ± 0.0
0.713GlnSer: 0.713 ± 0.315
1.427GlnThr: 1.427 ± 0.652
1.427GlnVal: 1.427 ± 1.934
0.713GlnTrp: 0.713 ± 0.315
1.427GlnTyr: 1.427 ± 0.652
0.0GlnXaa: 0.0 ± 0.0
Arg
7.846ArgAla: 7.846 ± 0.381
0.713ArgCys: 0.713 ± 0.967
3.566ArgAsp: 3.566 ± 1.575
6.419ArgGlu: 6.419 ± 2.835
2.853ArgPhe: 2.853 ± 0.022
5.706ArgGly: 5.706 ± 1.326
2.853ArgHis: 2.853 ± 1.26
3.566ArgIle: 3.566 ± 1.575
2.14ArgLys: 2.14 ± 0.337
7.133ArgLeu: 7.133 ± 0.586
0.0ArgMet: 0.0 ± 0.0
3.566ArgAsn: 3.566 ± 0.293
2.853ArgPro: 2.853 ± 1.304
1.427ArgGln: 1.427 ± 0.63
2.853ArgArg: 2.853 ± 0.022
3.566ArgSer: 3.566 ± 0.293
3.566ArgThr: 3.566 ± 2.271
4.993ArgVal: 4.993 ± 0.359
0.713ArgTrp: 0.713 ± 0.315
1.427ArgTyr: 1.427 ± 0.63
0.0ArgXaa: 0.0 ± 0.0
Ser
4.993SerAla: 4.993 ± 1.641
0.713SerCys: 0.713 ± 0.967
4.28SerAsp: 4.28 ± 1.956
1.427SerGlu: 1.427 ± 0.652
1.427SerPhe: 1.427 ± 0.63
4.28SerGly: 4.28 ± 0.608
1.427SerHis: 1.427 ± 0.63
2.853SerIle: 2.853 ± 1.26
2.14SerLys: 2.14 ± 0.337
8.559SerLeu: 8.559 ± 2.498
0.713SerMet: 0.713 ± 0.315
2.14SerAsn: 2.14 ± 0.337
6.419SerPro: 6.419 ± 0.271
1.427SerGln: 1.427 ± 0.652
5.706SerArg: 5.706 ± 1.238
11.412SerSer: 11.412 ± 1.37
4.28SerThr: 4.28 ± 0.608
0.713SerVal: 0.713 ± 0.315
1.427SerTrp: 1.427 ± 0.63
2.14SerTyr: 2.14 ± 0.337
0.0SerXaa: 0.0 ± 0.0
Thr
9.986ThrAla: 9.986 ± 3.282
3.566ThrCys: 3.566 ± 0.293
3.566ThrAsp: 3.566 ± 1.575
0.0ThrGlu: 0.0 ± 0.0
2.853ThrPhe: 2.853 ± 0.022
0.713ThrGly: 0.713 ± 0.315
0.713ThrHis: 0.713 ± 0.315
2.853ThrIle: 2.853 ± 1.304
1.427ThrLys: 1.427 ± 0.63
1.427ThrLeu: 1.427 ± 1.934
0.0ThrMet: 0.0 ± 0.0
3.566ThrAsn: 3.566 ± 0.989
2.14ThrPro: 2.14 ± 0.945
1.427ThrGln: 1.427 ± 0.63
2.853ThrArg: 2.853 ± 0.022
6.419ThrSer: 6.419 ± 0.271
6.419ThrThr: 6.419 ± 2.293
5.706ThrVal: 5.706 ± 6.454
1.427ThrTrp: 1.427 ± 1.934
1.427ThrTyr: 1.427 ± 0.63
0.0ThrXaa: 0.0 ± 0.0
Val
6.419ValAla: 6.419 ± 1.553
0.713ValCys: 0.713 ± 0.315
4.28ValAsp: 4.28 ± 3.238
2.14ValGlu: 2.14 ± 0.337
0.0ValPhe: 0.0 ± 0.0
5.706ValGly: 5.706 ± 2.608
0.713ValHis: 0.713 ± 0.315
1.427ValIle: 1.427 ± 1.934
9.272ValLys: 9.272 ± 1.033
5.706ValLeu: 5.706 ± 1.238
2.14ValMet: 2.14 ± 1.619
0.0ValAsn: 0.0 ± 0.0
0.713ValPro: 0.713 ± 0.967
3.566ValGln: 3.566 ± 0.293
6.419ValArg: 6.419 ± 1.553
7.133ValSer: 7.133 ± 0.696
4.28ValThr: 4.28 ± 1.956
6.419ValVal: 6.419 ± 1.011
0.713ValTrp: 0.713 ± 0.315
2.14ValTyr: 2.14 ± 1.619
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.713TrpAsp: 0.713 ± 0.315
0.713TrpGlu: 0.713 ± 0.315
0.713TrpPhe: 0.713 ± 0.315
0.713TrpGly: 0.713 ± 0.967
0.713TrpHis: 0.713 ± 0.315
0.713TrpIle: 0.713 ± 0.315
0.713TrpLys: 0.713 ± 0.315
2.14TrpLeu: 2.14 ± 0.945
0.0TrpMet: 0.0 ± 0.0
0.713TrpAsn: 0.713 ± 0.315
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.713TrpArg: 0.713 ± 0.967
2.14TrpSer: 2.14 ± 0.337
2.14TrpThr: 2.14 ± 1.619
0.713TrpVal: 0.713 ± 0.315
0.0TrpTrp: 0.0 ± 0.0
0.713TrpTyr: 0.713 ± 0.967
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.853TyrAla: 2.853 ± 0.022
0.0TyrCys: 0.0 ± 0.0
1.427TyrAsp: 1.427 ± 0.652
2.853TyrGlu: 2.853 ± 1.26
1.427TyrPhe: 1.427 ± 0.63
4.993TyrGly: 4.993 ± 2.205
0.0TyrHis: 0.0 ± 0.0
1.427TyrIle: 1.427 ± 0.652
3.566TyrLys: 3.566 ± 1.575
3.566TyrLeu: 3.566 ± 0.989
0.713TyrMet: 0.713 ± 0.315
1.427TyrAsn: 1.427 ± 0.652
0.0TyrPro: 0.0 ± 0.0
1.427TyrGln: 1.427 ± 0.63
2.14TyrArg: 2.14 ± 0.945
0.713TyrSer: 0.713 ± 0.967
0.713TyrThr: 0.713 ± 0.967
1.427TyrVal: 1.427 ± 0.63
0.0TyrTrp: 0.0 ± 0.0
3.566TyrTyr: 3.566 ± 1.575
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1403 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski