Amino acid dipepetide frequency for Christensenella minuta

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.052AlaAla: 11.052 ± 0.176	1.416AlaCys: 1.416 ± 0.045	5.42AlaAsp: 5.42 ± 0.095	6.724AlaGlu: 6.724 ± 0.091	3.582AlaPhe: 3.582 ± 0.069	8.279AlaGly: 8.279 ± 0.134	1.407AlaHis: 1.407 ± 0.041	5.067AlaIle: 5.067 ± 0.088	5.283AlaLys: 5.283 ± 0.088	8.336AlaLeu: 8.336 ± 0.117	2.565AlaMet: 2.565 ± 0.062	2.823AlaAsn: 2.823 ± 0.059	2.969AlaPro: 2.969 ± 0.071	3.43AlaGln: 3.43 ± 0.06	4.216AlaArg: 4.216 ± 0.08	4.303AlaSer: 4.303 ± 0.084	3.35AlaThr: 3.35 ± 0.074	7.959AlaVal: 7.959 ± 0.106	0.676AlaTrp: 0.676 ± 0.028	2.834AlaTyr: 2.834 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	1.565CysAla: 1.565 ± 0.05	0.256CysCys: 0.256 ± 0.02	0.751CysAsp: 0.751 ± 0.031	0.856CysGlu: 0.856 ± 0.032	0.585CysPhe: 0.585 ± 0.028	1.845CysGly: 1.845 ± 0.06	0.219CysHis: 0.219 ± 0.015	0.954CysIle: 0.954 ± 0.035	0.678CysLys: 0.678 ± 0.028	1.057CysLeu: 1.057 ± 0.035	0.451CysMet: 0.451 ± 0.024	0.444CysAsn: 0.444 ± 0.022	0.659CysPro: 0.659 ± 0.033	0.282CysGln: 0.282 ± 0.019	0.807CysArg: 0.807 ± 0.033	0.785CysSer: 0.785 ± 0.033	0.777CysThr: 0.777 ± 0.033	1.115CysVal: 1.115 ± 0.036	0.112CysTrp: 0.112 ± 0.012	0.459CysTyr: 0.459 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	4.955AspAla: 4.955 ± 0.09	0.737AspCys: 0.737 ± 0.03	2.67AspAsp: 2.67 ± 0.068	4.263AspGlu: 4.263 ± 0.081	2.51AspPhe: 2.51 ± 0.058	5.01AspGly: 5.01 ± 0.086	0.766AspHis: 0.766 ± 0.033	4.529AspIle: 4.529 ± 0.07	2.945AspLys: 2.945 ± 0.067	4.379AspLeu: 4.379 ± 0.071	1.931AspMet: 1.931 ± 0.05	1.766AspAsn: 1.766 ± 0.047	2.129AspPro: 2.129 ± 0.058	1.153AspGln: 1.153 ± 0.036	2.564AspArg: 2.564 ± 0.06	2.608AspSer: 2.608 ± 0.063	2.997AspThr: 2.997 ± 0.063	4.002AspVal: 4.002 ± 0.066	0.549AspTrp: 0.549 ± 0.027	2.312AspTyr: 2.312 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	6.289GluAla: 6.289 ± 0.099	0.801GluCys: 0.801 ± 0.036	3.642GluAsp: 3.642 ± 0.068	5.855GluGlu: 5.855 ± 0.106	2.482GluPhe: 2.482 ± 0.061	4.62GluGly: 4.62 ± 0.082	1.17GluHis: 1.17 ± 0.038	5.187GluIle: 5.187 ± 0.101	5.687GluLys: 5.687 ± 0.094	6.388GluLeu: 6.388 ± 0.091	2.424GluMet: 2.424 ± 0.054	3.644GluAsn: 3.644 ± 0.063	2.305GluPro: 2.305 ± 0.061	2.748GluGln: 2.748 ± 0.064	3.903GluArg: 3.903 ± 0.076	3.003GluSer: 3.003 ± 0.062	3.976GluThr: 3.976 ± 0.083	4.201GluVal: 4.201 ± 0.08	0.715GluTrp: 0.715 ± 0.031	2.984GluTyr: 2.984 ± 0.065	0.0GluXaa: 0.0 ± 0.0
Phe	3.69PheAla: 3.69 ± 0.074	0.682PheCys: 0.682 ± 0.03	2.552PheAsp: 2.552 ± 0.061	2.647PheGlu: 2.647 ± 0.052	1.967PhePhe: 1.967 ± 0.063	3.253PheGly: 3.253 ± 0.063	0.703PheHis: 0.703 ± 0.03	2.666PheIle: 2.666 ± 0.06	1.726PheLys: 1.726 ± 0.049	3.875PheLeu: 3.875 ± 0.09	1.212PheMet: 1.212 ± 0.043	1.354PheAsn: 1.354 ± 0.032	1.58PhePro: 1.58 ± 0.049	1.045PheGln: 1.045 ± 0.033	1.838PheArg: 1.838 ± 0.044	2.842PheSer: 2.842 ± 0.061	2.434PheThr: 2.434 ± 0.067	2.847PheVal: 2.847 ± 0.064	0.373PheTrp: 0.373 ± 0.024	1.506PheTyr: 1.506 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	6.849GlyAla: 6.849 ± 0.105	1.312GlyCys: 1.312 ± 0.043	3.707GlyAsp: 3.707 ± 0.07	5.526GlyGlu: 5.526 ± 0.091	3.268GlyPhe: 3.268 ± 0.061	6.76GlyGly: 6.76 ± 0.147	1.297GlyHis: 1.297 ± 0.042	6.469GlyIle: 6.469 ± 0.105	5.623GlyLys: 5.623 ± 0.08	6.607GlyLeu: 6.607 ± 0.112	2.743GlyMet: 2.743 ± 0.059	3.026GlyAsn: 3.026 ± 0.081	1.702GlyPro: 1.702 ± 0.052	2.282GlyGln: 2.282 ± 0.047	4.136GlyArg: 4.136 ± 0.073	4.28GlySer: 4.28 ± 0.088	4.906GlyThr: 4.906 ± 0.112	5.83GlyVal: 5.83 ± 0.09	0.702GlyTrp: 0.702 ± 0.034	3.272GlyTyr: 3.272 ± 0.065	0.0GlyXaa: 0.0 ± 0.0
His	1.383HisAla: 1.383 ± 0.039	0.256HisCys: 0.256 ± 0.017	0.825HisAsp: 0.825 ± 0.031	1.071HisGlu: 1.071 ± 0.03	0.782HisPhe: 0.782 ± 0.033	1.361HisGly: 1.361 ± 0.04	0.323HisHis: 0.323 ± 0.019	1.345HisIle: 1.345 ± 0.038	0.862HisLys: 0.862 ± 0.033	1.272HisLeu: 1.272 ± 0.04	0.497HisMet: 0.497 ± 0.024	0.593HisAsn: 0.593 ± 0.026	0.851HisPro: 0.851 ± 0.034	0.391HisGln: 0.391 ± 0.022	0.778HisArg: 0.778 ± 0.03	0.915HisSer: 0.915 ± 0.034	0.979HisThr: 0.979 ± 0.033	1.033HisVal: 1.033 ± 0.036	0.149HisTrp: 0.149 ± 0.014	0.615HisTyr: 0.615 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.43IleAla: 6.43 ± 0.086	1.097IleCys: 1.097 ± 0.035	4.068IleAsp: 4.068 ± 0.069	4.355IleGlu: 4.355 ± 0.078	2.719IlePhe: 2.719 ± 0.063	5.394IleGly: 5.394 ± 0.084	1.093IleHis: 1.093 ± 0.036	4.624IleIle: 4.624 ± 0.086	3.479IleLys: 3.479 ± 0.076	6.442IleLeu: 6.442 ± 0.116	1.881IleMet: 1.881 ± 0.045	2.404IleAsn: 2.404 ± 0.054	2.987IlePro: 2.987 ± 0.066	1.574IleGln: 1.574 ± 0.04	3.574IleArg: 3.574 ± 0.074	4.412IleSer: 4.412 ± 0.081	3.882IleThr: 3.882 ± 0.064	5.081IleVal: 5.081 ± 0.071	0.505IleTrp: 0.505 ± 0.026	2.205IleTyr: 2.205 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	4.886LysAla: 4.886 ± 0.081	0.711LysCys: 0.711 ± 0.031	3.316LysAsp: 3.316 ± 0.067	5.006LysGlu: 5.006 ± 0.07	1.771LysPhe: 1.771 ± 0.052	4.014LysGly: 4.014 ± 0.07	0.977LysHis: 0.977 ± 0.033	4.268LysIle: 4.268 ± 0.071	5.485LysLys: 5.485 ± 0.089	4.889LysLeu: 4.889 ± 0.078	2.103LysMet: 2.103 ± 0.05	3.145LysAsn: 3.145 ± 0.065	2.061LysPro: 2.061 ± 0.051	2.276LysGln: 2.276 ± 0.052	3.405LysArg: 3.405 ± 0.075	2.958LysSer: 2.958 ± 0.058	3.706LysThr: 3.706 ± 0.076	3.563LysVal: 3.563 ± 0.074	0.541LysTrp: 0.541 ± 0.027	2.346LysTyr: 2.346 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	8.172LeuAla: 8.172 ± 0.113	1.612LeuCys: 1.612 ± 0.044	4.66LeuAsp: 4.66 ± 0.081	5.508LeuGlu: 5.508 ± 0.087	3.84LeuPhe: 3.84 ± 0.088	6.434LeuGly: 6.434 ± 0.089	1.535LeuHis: 1.535 ± 0.045	5.31LeuIle: 5.31 ± 0.087	5.611LeuLys: 5.611 ± 0.084	8.19LeuLeu: 8.19 ± 0.147	2.712LeuMet: 2.712 ± 0.07	3.308LeuAsn: 3.308 ± 0.065	3.791LeuPro: 3.791 ± 0.077	2.547LeuGln: 2.547 ± 0.053	4.722LeuArg: 4.722 ± 0.082	5.964LeuSer: 5.964 ± 0.086	4.77LeuThr: 4.77 ± 0.088	5.593LeuVal: 5.593 ± 0.091	0.704LeuTrp: 0.704 ± 0.031	3.042LeuTyr: 3.042 ± 0.069	0.0LeuXaa: 0.0 ± 0.0
Met	2.518MetAla: 2.518 ± 0.05	0.375MetCys: 0.375 ± 0.022	1.979MetAsp: 1.979 ± 0.045	2.428MetGlu: 2.428 ± 0.054	0.994MetPhe: 0.994 ± 0.039	2.311MetGly: 2.311 ± 0.055	0.496MetHis: 0.496 ± 0.025	1.99MetIle: 1.99 ± 0.055	2.331MetLys: 2.331 ± 0.05	2.832MetLeu: 2.832 ± 0.066	1.02MetMet: 1.02 ± 0.036	1.401MetAsn: 1.401 ± 0.041	1.318MetPro: 1.318 ± 0.04	1.109MetGln: 1.109 ± 0.032	1.66MetArg: 1.66 ± 0.047	1.606MetSer: 1.606 ± 0.043	1.78MetThr: 1.78 ± 0.044	1.861MetVal: 1.861 ± 0.045	0.208MetTrp: 0.208 ± 0.015	0.792MetTyr: 0.792 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.371AsnAla: 3.371 ± 0.063	0.538AsnCys: 0.538 ± 0.027	1.911AsnAsp: 1.911 ± 0.046	2.427AsnGlu: 2.427 ± 0.053	1.511AsnPhe: 1.511 ± 0.049	3.507AsnGly: 3.507 ± 0.07	0.584AsnHis: 0.584 ± 0.026	3.082AsnIle: 3.082 ± 0.058	1.984AsnLys: 1.984 ± 0.052	3.206AsnLeu: 3.206 ± 0.06	1.3AsnMet: 1.3 ± 0.038	1.42AsnAsn: 1.42 ± 0.045	1.847AsnPro: 1.847 ± 0.046	1.048AsnGln: 1.048 ± 0.029	1.796AsnArg: 1.796 ± 0.046	1.93AsnSer: 1.93 ± 0.054	2.139AsnThr: 2.139 ± 0.054	2.705AsnVal: 2.705 ± 0.055	0.335AsnTrp: 0.335 ± 0.02	1.431AsnTyr: 1.431 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	3.747ProAla: 3.747 ± 0.077	0.546ProCys: 0.546 ± 0.024	2.533ProAsp: 2.533 ± 0.056	3.655ProGlu: 3.655 ± 0.071	1.694ProPhe: 1.694 ± 0.046	2.93ProGly: 2.93 ± 0.062	0.704ProHis: 0.704 ± 0.028	1.864ProIle: 1.864 ± 0.038	1.813ProLys: 1.813 ± 0.044	3.014ProLeu: 3.014 ± 0.062	0.914ProMet: 0.914 ± 0.031	1.175ProAsn: 1.175 ± 0.041	1.179ProPro: 1.179 ± 0.039	1.482ProGln: 1.482 ± 0.046	1.49ProArg: 1.49 ± 0.043	1.955ProSer: 1.955 ± 0.05	1.785ProThr: 1.785 ± 0.055	3.268ProVal: 3.268 ± 0.06	0.294ProTrp: 0.294 ± 0.019	1.459ProTyr: 1.459 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	2.957GlnAla: 2.957 ± 0.062	0.314GlnCys: 0.314 ± 0.018	1.615GlnAsp: 1.615 ± 0.042	2.566GlnGlu: 2.566 ± 0.063	1.047GlnPhe: 1.047 ± 0.033	2.12GlnGly: 2.12 ± 0.05	0.41GlnHis: 0.41 ± 0.024	2.087GlnIle: 2.087 ± 0.048	2.558GlnLys: 2.558 ± 0.056	2.511GlnLeu: 2.511 ± 0.054	1.034GlnMet: 1.034 ± 0.037	1.451GlnAsn: 1.451 ± 0.039	1.206GlnPro: 1.206 ± 0.045	1.262GlnGln: 1.262 ± 0.042	1.643GlnArg: 1.643 ± 0.053	1.577GlnSer: 1.577 ± 0.05	1.611GlnThr: 1.611 ± 0.046	1.874GlnVal: 1.874 ± 0.049	0.272GlnTrp: 0.272 ± 0.018	1.245GlnTyr: 1.245 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	4.047ArgAla: 4.047 ± 0.07	0.636ArgCys: 0.636 ± 0.032	2.594ArgAsp: 2.594 ± 0.051	4.596ArgGlu: 4.596 ± 0.087	2.085ArgPhe: 2.085 ± 0.049	3.408ArgGly: 3.408 ± 0.062	0.851ArgHis: 0.851 ± 0.031	3.69ArgIle: 3.69 ± 0.073	3.425ArgLys: 3.425 ± 0.069	4.395ArgLeu: 4.395 ± 0.079	1.721ArgMet: 1.721 ± 0.045	1.99ArgAsn: 1.99 ± 0.051	1.743ArgPro: 1.743 ± 0.046	1.934ArgGln: 1.934 ± 0.054	3.174ArgArg: 3.174 ± 0.069	2.359ArgSer: 2.359 ± 0.051	2.592ArgThr: 2.592 ± 0.051	3.135ArgVal: 3.135 ± 0.068	0.426ArgTrp: 0.426 ± 0.024	1.885ArgTyr: 1.885 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.976SerAla: 4.976 ± 0.099	0.724SerCys: 0.724 ± 0.028	2.741SerAsp: 2.741 ± 0.051	3.375SerGlu: 3.375 ± 0.063	2.583SerPhe: 2.583 ± 0.06	5.674SerGly: 5.674 ± 0.095	0.91SerHis: 0.91 ± 0.032	3.752SerIle: 3.752 ± 0.066	2.737SerLys: 2.737 ± 0.061	4.726SerLeu: 4.726 ± 0.084	1.616SerMet: 1.616 ± 0.046	1.729SerAsn: 1.729 ± 0.044	2.023SerPro: 2.023 ± 0.049	1.557SerGln: 1.557 ± 0.042	2.708SerArg: 2.708 ± 0.051	3.019SerSer: 3.019 ± 0.071	2.578SerThr: 2.578 ± 0.06	4.21SerVal: 4.21 ± 0.075	0.408SerTrp: 0.408 ± 0.023	2.009SerTyr: 2.009 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	5.41ThrAla: 5.41 ± 0.118	0.618ThrCys: 0.618 ± 0.025	3.177ThrAsp: 3.177 ± 0.074	3.582ThrGlu: 3.582 ± 0.074	2.1ThrPhe: 2.1 ± 0.054	5.126ThrGly: 5.126 ± 0.086	0.906ThrHis: 0.906 ± 0.033	3.406ThrIle: 3.406 ± 0.063	2.745ThrLys: 2.745 ± 0.055	4.885ThrLeu: 4.885 ± 0.079	1.361ThrMet: 1.361 ± 0.04	1.798ThrAsn: 1.798 ± 0.052	2.498ThrPro: 2.498 ± 0.063	1.692ThrGln: 1.692 ± 0.049	2.237ThrArg: 2.237 ± 0.052	2.55ThrSer: 2.55 ± 0.07	2.466ThrThr: 2.466 ± 0.072	4.867ThrVal: 4.867 ± 0.106	0.393ThrTrp: 0.393 ± 0.022	1.659ThrTyr: 1.659 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	5.665ValAla: 5.665 ± 0.079	1.332ValCys: 1.332 ± 0.046	3.793ValAsp: 3.793 ± 0.064	4.441ValGlu: 4.441 ± 0.08	3.27ValPhe: 3.27 ± 0.06	4.699ValGly: 4.699 ± 0.079	1.058ValHis: 1.058 ± 0.041	4.901ValIle: 4.901 ± 0.088	4.128ValLys: 4.128 ± 0.087	7.146ValLeu: 7.146 ± 0.107	2.262ValMet: 2.262 ± 0.052	2.775ValAsn: 2.775 ± 0.066	2.943ValPro: 2.943 ± 0.059	2.043ValGln: 2.043 ± 0.049	3.686ValArg: 3.686 ± 0.077	4.504ValSer: 4.504 ± 0.073	4.251ValThr: 4.251 ± 0.109	4.958ValVal: 4.958 ± 0.092	0.592ValTrp: 0.592 ± 0.027	2.48ValTyr: 2.48 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.646TrpAla: 0.646 ± 0.03	0.111TrpCys: 0.111 ± 0.011	0.501TrpAsp: 0.501 ± 0.028	0.563TrpGlu: 0.563 ± 0.024	0.39TrpPhe: 0.39 ± 0.019	0.591TrpGly: 0.591 ± 0.027	0.172TrpHis: 0.172 ± 0.014	0.576TrpIle: 0.576 ± 0.03	0.556TrpLys: 0.556 ± 0.028	0.798TrpLeu: 0.798 ± 0.029	0.291TrpMet: 0.291 ± 0.021	0.426TrpAsn: 0.426 ± 0.023	0.219TrpPro: 0.219 ± 0.016	0.384TrpGln: 0.384 ± 0.019	0.41TrpArg: 0.41 ± 0.021	0.457TrpSer: 0.457 ± 0.025	0.39TrpThr: 0.39 ± 0.019	0.458TrpVal: 0.458 ± 0.024	0.118TrpTrp: 0.118 ± 0.012	0.328TrpTyr: 0.328 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.085TyrAla: 3.085 ± 0.062	0.586TyrCys: 0.586 ± 0.026	2.321TyrAsp: 2.321 ± 0.055	2.582TyrGlu: 2.582 ± 0.065	1.614TyrPhe: 1.614 ± 0.043	2.96TyrGly: 2.96 ± 0.064	0.704TyrHis: 0.704 ± 0.027	2.439TyrIle: 2.439 ± 0.051	1.767TyrLys: 1.767 ± 0.049	3.078TyrLeu: 3.078 ± 0.067	0.967TyrMet: 0.967 ± 0.034	1.4TyrAsn: 1.4 ± 0.046	1.49TyrPro: 1.49 ± 0.044	1.12TyrGln: 1.12 ± 0.038	1.938TyrArg: 1.938 ± 0.052	2.028TyrSer: 2.028 ± 0.047	2.105TyrThr: 2.105 ± 0.056	2.368TyrVal: 2.368 ± 0.054	0.311TyrTrp: 0.311 ± 0.019	1.495TyrTyr: 1.495 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3119 proteins (890553 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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