Amino acid dipepetide frequency for Aurantiacibacter xanthus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.417AlaAla: 17.417 ± 0.172	1.085AlaCys: 1.085 ± 0.031	7.364AlaAsp: 7.364 ± 0.084	8.269AlaGlu: 8.269 ± 0.107	4.266AlaPhe: 4.266 ± 0.058	11.087AlaGly: 11.087 ± 0.099	2.268AlaHis: 2.268 ± 0.042	6.566AlaIle: 6.566 ± 0.077	3.55AlaLys: 3.55 ± 0.075	13.875AlaLeu: 13.875 ± 0.151	3.938AlaMet: 3.938 ± 0.061	3.33AlaAsn: 3.33 ± 0.054	6.133AlaPro: 6.133 ± 0.078	4.934AlaGln: 4.934 ± 0.076	9.575AlaArg: 9.575 ± 0.112	7.241AlaSer: 7.241 ± 0.079	6.049AlaThr: 6.049 ± 0.076	8.078AlaVal: 8.078 ± 0.094	1.551AlaTrp: 1.551 ± 0.033	2.72AlaTyr: 2.72 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	1.113CysAla: 1.113 ± 0.033	0.11CysCys: 0.11 ± 0.009	0.593CysAsp: 0.593 ± 0.021	0.526CysGlu: 0.526 ± 0.022	0.308CysPhe: 0.308 ± 0.017	0.885CysGly: 0.885 ± 0.026	0.235CysHis: 0.235 ± 0.014	0.317CysIle: 0.317 ± 0.016	0.161CysLys: 0.161 ± 0.011	0.762CysLeu: 0.762 ± 0.023	0.152CysMet: 0.152 ± 0.011	0.213CysAsn: 0.213 ± 0.013	0.453CysPro: 0.453 ± 0.02	0.237CysGln: 0.237 ± 0.014	0.562CysArg: 0.562 ± 0.02	0.51CysSer: 0.51 ± 0.021	0.412CysThr: 0.412 ± 0.02	0.575CysVal: 0.575 ± 0.023	0.119CysTrp: 0.119 ± 0.009	0.178CysTyr: 0.178 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.135AspAla: 7.135 ± 0.094	0.534AspCys: 0.534 ± 0.022	3.479AspAsp: 3.479 ± 0.054	3.872AspGlu: 3.872 ± 0.057	2.287AspPhe: 2.287 ± 0.051	5.62AspGly: 5.62 ± 0.081	1.313AspHis: 1.313 ± 0.036	2.833AspIle: 2.833 ± 0.053	1.726AspLys: 1.726 ± 0.047	6.051AspLeu: 6.051 ± 0.071	1.473AspMet: 1.473 ± 0.039	1.508AspAsn: 1.508 ± 0.04	3.891AspPro: 3.891 ± 0.057	1.766AspGln: 1.766 ± 0.038	4.393AspArg: 4.393 ± 0.059	2.522AspSer: 2.522 ± 0.055	2.674AspThr: 2.674 ± 0.054	3.802AspVal: 3.802 ± 0.051	1.177AspTrp: 1.177 ± 0.034	1.77AspTyr: 1.77 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	8.448GluAla: 8.448 ± 0.109	0.376GluCys: 0.376 ± 0.016	3.31GluAsp: 3.31 ± 0.058	3.72GluGlu: 3.72 ± 0.07	1.753GluPhe: 1.753 ± 0.035	5.134GluGly: 5.134 ± 0.066	1.286GluHis: 1.286 ± 0.039	2.984GluIle: 2.984 ± 0.052	1.97GluLys: 1.97 ± 0.046	5.804GluLeu: 5.804 ± 0.068	1.525GluMet: 1.525 ± 0.037	1.601GluAsn: 1.601 ± 0.036	2.857GluPro: 2.857 ± 0.051	2.589GluGln: 2.589 ± 0.044	5.204GluArg: 5.204 ± 0.072	2.383GluSer: 2.383 ± 0.048	3.17GluThr: 3.17 ± 0.052	4.31GluVal: 4.31 ± 0.06	0.893GluTrp: 0.893 ± 0.028	1.094GluTyr: 1.094 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	5.102PheAla: 5.102 ± 0.066	0.362PheCys: 0.362 ± 0.018	2.857PheAsp: 2.857 ± 0.049	2.134PheGlu: 2.134 ± 0.041	1.239PhePhe: 1.239 ± 0.035	3.634PheGly: 3.634 ± 0.065	0.697PheHis: 0.697 ± 0.026	1.47PheIle: 1.47 ± 0.036	0.764PheLys: 0.764 ± 0.025	2.982PheLeu: 2.982 ± 0.059	0.76PheMet: 0.76 ± 0.023	1.056PheAsn: 1.056 ± 0.036	1.555PhePro: 1.555 ± 0.031	0.902PheGln: 0.902 ± 0.027	2.103PheArg: 2.103 ± 0.038	2.195PheSer: 2.195 ± 0.044	2.19PheThr: 2.19 ± 0.049	2.688PheVal: 2.688 ± 0.047	0.514PheTrp: 0.514 ± 0.021	0.942PheTyr: 0.942 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.671GlyAla: 9.671 ± 0.117	0.828GlyCys: 0.828 ± 0.027	4.903GlyAsp: 4.903 ± 0.069	5.595GlyGlu: 5.595 ± 0.075	3.548GlyPhe: 3.548 ± 0.056	7.969GlyGly: 7.969 ± 0.123	1.813GlyHis: 1.813 ± 0.039	4.117GlyIle: 4.117 ± 0.063	3.323GlyLys: 3.323 ± 0.062	8.596GlyLeu: 8.596 ± 0.096	2.392GlyMet: 2.392 ± 0.041	2.464GlyAsn: 2.464 ± 0.053	3.72GlyPro: 3.72 ± 0.054	3.056GlyGln: 3.056 ± 0.052	5.881GlyArg: 5.881 ± 0.061	5.123GlySer: 5.123 ± 0.079	5.034GlyThr: 5.034 ± 0.1	6.098GlyVal: 6.098 ± 0.072	1.606GlyTrp: 1.606 ± 0.037	2.361GlyTyr: 2.361 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.27HisAla: 2.27 ± 0.046	0.241HisCys: 0.241 ± 0.014	1.16HisAsp: 1.16 ± 0.031	1.101HisGlu: 1.101 ± 0.031	0.855HisPhe: 0.855 ± 0.028	1.828HisGly: 1.828 ± 0.046	0.577HisHis: 0.577 ± 0.026	0.863HisIle: 0.863 ± 0.029	0.484HisLys: 0.484 ± 0.018	1.866HisLeu: 1.866 ± 0.04	0.416HisMet: 0.416 ± 0.016	0.473HisAsn: 0.473 ± 0.02	1.252HisPro: 1.252 ± 0.035	0.53HisGln: 0.53 ± 0.019	1.396HisArg: 1.396 ± 0.031	0.963HisSer: 0.963 ± 0.03	0.751HisThr: 0.751 ± 0.024	1.379HisVal: 1.379 ± 0.036	0.377HisTrp: 0.377 ± 0.018	0.591HisTyr: 0.591 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.413IleAla: 7.413 ± 0.09	0.449IleCys: 0.449 ± 0.02	3.749IleAsp: 3.749 ± 0.054	3.653IleGlu: 3.653 ± 0.065	1.424IlePhe: 1.424 ± 0.041	4.657IleGly: 4.657 ± 0.067	0.808IleHis: 0.808 ± 0.023	1.845IleIle: 1.845 ± 0.039	1.097IleLys: 1.097 ± 0.031	3.533IleLeu: 3.533 ± 0.059	0.903IleMet: 0.903 ± 0.025	1.369IleAsn: 1.369 ± 0.032	2.124IlePro: 2.124 ± 0.041	1.05IleGln: 1.05 ± 0.03	2.885IleArg: 2.885 ± 0.052	2.624IleSer: 2.624 ± 0.048	2.69IleThr: 2.69 ± 0.051	3.901IleVal: 3.901 ± 0.058	0.554IleTrp: 0.554 ± 0.023	1.069IleTyr: 1.069 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.744LysAla: 3.744 ± 0.069	0.155LysCys: 0.155 ± 0.01	1.422LysAsp: 1.422 ± 0.041	1.339LysGlu: 1.339 ± 0.04	0.786LysPhe: 0.786 ± 0.027	2.435LysGly: 2.435 ± 0.049	0.533LysHis: 0.533 ± 0.017	1.357LysIle: 1.357 ± 0.043	0.941LysLys: 0.941 ± 0.039	3.017LysLeu: 3.017 ± 0.048	0.67LysMet: 0.67 ± 0.025	0.677LysAsn: 0.677 ± 0.026	1.789LysPro: 1.789 ± 0.043	0.885LysGln: 0.885 ± 0.029	2.04LysArg: 2.04 ± 0.051	1.497LysSer: 1.497 ± 0.032	1.48LysThr: 1.48 ± 0.039	2.2LysVal: 2.2 ± 0.052	0.373LysTrp: 0.373 ± 0.017	0.524LysTyr: 0.524 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.817LeuAla: 14.817 ± 0.147	0.838LeuCys: 0.838 ± 0.024	6.239LeuAsp: 6.239 ± 0.077	5.331LeuGlu: 5.331 ± 0.076	3.623LeuPhe: 3.623 ± 0.06	8.531LeuGly: 8.531 ± 0.093	1.706LeuHis: 1.706 ± 0.037	4.503LeuIle: 4.503 ± 0.064	2.75LeuLys: 2.75 ± 0.054	9.288LeuLeu: 9.288 ± 0.133	2.077LeuMet: 2.077 ± 0.043	2.397LeuAsn: 2.397 ± 0.047	5.528LeuPro: 5.528 ± 0.067	2.622LeuGln: 2.622 ± 0.045	6.967LeuArg: 6.967 ± 0.086	6.188LeuSer: 6.188 ± 0.076	5.696LeuThr: 5.696 ± 0.074	7.517LeuVal: 7.517 ± 0.096	1.197LeuTrp: 1.197 ± 0.034	1.902LeuTyr: 1.902 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	3.331MetAla: 3.331 ± 0.048	0.149MetCys: 0.149 ± 0.01	1.16MetAsp: 1.16 ± 0.03	1.107MetGlu: 1.107 ± 0.029	0.702MetPhe: 0.702 ± 0.026	1.907MetGly: 1.907 ± 0.043	0.476MetHis: 0.476 ± 0.019	1.268MetIle: 1.268 ± 0.039	0.816MetLys: 0.816 ± 0.022	2.627MetLeu: 2.627 ± 0.046	0.607MetMet: 0.607 ± 0.025	0.681MetAsn: 0.681 ± 0.022	1.495MetPro: 1.495 ± 0.035	0.829MetGln: 0.829 ± 0.025	1.82MetArg: 1.82 ± 0.038	1.487MetSer: 1.487 ± 0.038	1.683MetThr: 1.683 ± 0.036	1.719MetVal: 1.719 ± 0.036	0.236MetTrp: 0.236 ± 0.014	0.285MetTyr: 0.285 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.342AsnAla: 3.342 ± 0.051	0.268AsnCys: 0.268 ± 0.016	1.477AsnAsp: 1.477 ± 0.039	1.248AsnGlu: 1.248 ± 0.038	1.056AsnPhe: 1.056 ± 0.03	2.46AsnGly: 2.46 ± 0.052	0.501AsnHis: 0.501 ± 0.018	1.231AsnIle: 1.231 ± 0.033	0.617AsnLys: 0.617 ± 0.027	2.628AsnLeu: 2.628 ± 0.056	0.556AsnMet: 0.556 ± 0.022	0.751AsnAsn: 0.751 ± 0.027	1.887AsnPro: 1.887 ± 0.046	0.771AsnGln: 0.771 ± 0.027	1.842AsnArg: 1.842 ± 0.042	1.419AsnSer: 1.419 ± 0.039	1.279AsnThr: 1.279 ± 0.038	1.932AsnVal: 1.932 ± 0.045	0.5AsnTrp: 0.5 ± 0.02	0.75AsnTyr: 0.75 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	6.825ProAla: 6.825 ± 0.079	0.343ProCys: 0.343 ± 0.017	3.642ProAsp: 3.642 ± 0.058	4.137ProGlu: 4.137 ± 0.063	1.965ProPhe: 1.965 ± 0.037	4.677ProGly: 4.677 ± 0.07	0.991ProHis: 0.991 ± 0.026	2.228ProIle: 2.228 ± 0.05	1.244ProLys: 1.244 ± 0.034	5.021ProLeu: 5.021 ± 0.07	1.149ProMet: 1.149 ± 0.03	1.299ProAsn: 1.299 ± 0.032	2.624ProPro: 2.624 ± 0.06	1.876ProGln: 1.876 ± 0.038	2.995ProArg: 2.995 ± 0.051	2.872ProSer: 2.872 ± 0.049	2.492ProThr: 2.492 ± 0.047	4.241ProVal: 4.241 ± 0.065	0.671ProTrp: 0.671 ± 0.029	1.101ProTyr: 1.101 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.211GlnAla: 4.211 ± 0.056	0.253GlnCys: 0.253 ± 0.013	1.525GlnAsp: 1.525 ± 0.039	1.52GlnGlu: 1.52 ± 0.039	1.197GlnPhe: 1.197 ± 0.025	2.543GlnGly: 2.543 ± 0.046	0.596GlnHis: 0.596 ± 0.021	1.748GlnIle: 1.748 ± 0.043	0.745GlnLys: 0.745 ± 0.027	3.396GlnLeu: 3.396 ± 0.06	0.918GlnMet: 0.918 ± 0.032	0.843GlnAsn: 0.843 ± 0.026	1.911GlnPro: 1.911 ± 0.041	1.303GlnGln: 1.303 ± 0.036	2.555GlnArg: 2.555 ± 0.054	1.884GlnSer: 1.884 ± 0.038	1.75GlnThr: 1.75 ± 0.042	2.459GlnVal: 2.459 ± 0.043	0.461GlnTrp: 0.461 ± 0.018	0.731GlnTyr: 0.731 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.319ArgAla: 8.319 ± 0.095	0.504ArgCys: 0.504 ± 0.023	4.055ArgAsp: 4.055 ± 0.055	4.642ArgGlu: 4.642 ± 0.071	2.963ArgPhe: 2.963 ± 0.046	4.869ArgGly: 4.869 ± 0.069	1.564ArgHis: 1.564 ± 0.039	3.914ArgIle: 3.914 ± 0.059	2.213ArgLys: 2.213 ± 0.043	8.036ArgLeu: 8.036 ± 0.098	1.845ArgMet: 1.845 ± 0.043	1.938ArgAsn: 1.938 ± 0.039	3.35ArgPro: 3.35 ± 0.055	2.564ArgGln: 2.564 ± 0.041	5.363ArgArg: 5.363 ± 0.08	3.8ArgSer: 3.8 ± 0.054	3.276ArgThr: 3.276 ± 0.053	4.5ArgVal: 4.5 ± 0.07	1.173ArgTrp: 1.173 ± 0.028	1.844ArgTyr: 1.844 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.855SerAla: 6.855 ± 0.091	0.454SerCys: 0.454 ± 0.022	3.376SerAsp: 3.376 ± 0.053	3.137SerGlu: 3.137 ± 0.052	2.202SerPhe: 2.202 ± 0.046	5.868SerGly: 5.868 ± 0.106	1.013SerHis: 1.013 ± 0.032	2.454SerIle: 2.454 ± 0.049	1.4SerLys: 1.4 ± 0.039	5.597SerLeu: 5.597 ± 0.074	1.224SerMet: 1.224 ± 0.033	1.465SerAsn: 1.465 ± 0.043	2.886SerPro: 2.886 ± 0.05	1.693SerGln: 1.693 ± 0.037	3.666SerArg: 3.666 ± 0.057	3.195SerSer: 3.195 ± 0.076	2.77SerThr: 2.77 ± 0.047	3.831SerVal: 3.831 ± 0.058	0.842SerTrp: 0.842 ± 0.029	1.488SerTyr: 1.488 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.912ThrAla: 5.912 ± 0.078	0.476ThrCys: 0.476 ± 0.022	2.956ThrAsp: 2.956 ± 0.055	2.556ThrGlu: 2.556 ± 0.051	1.962ThrPhe: 1.962 ± 0.043	5.397ThrGly: 5.397 ± 0.106	0.881ThrHis: 0.881 ± 0.026	2.905ThrIle: 2.905 ± 0.053	1.223ThrLys: 1.223 ± 0.033	5.58ThrLeu: 5.58 ± 0.088	1.21ThrMet: 1.21 ± 0.032	1.364ThrAsn: 1.364 ± 0.036	3.205ThrPro: 3.205 ± 0.057	1.517ThrGln: 1.517 ± 0.035	3.473ThrArg: 3.473 ± 0.056	2.97ThrSer: 2.97 ± 0.047	2.682ThrThr: 2.682 ± 0.058	4.103ThrVal: 4.103 ± 0.057	0.653ThrTrp: 0.653 ± 0.023	1.362ThrTyr: 1.362 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	9.195ValAla: 9.195 ± 0.1	0.583ValCys: 0.583 ± 0.019	4.189ValAsp: 4.189 ± 0.062	4.576ValGlu: 4.576 ± 0.063	2.457ValPhe: 2.457 ± 0.043	5.449ValGly: 5.449 ± 0.076	1.273ValHis: 1.273 ± 0.033	3.644ValIle: 3.644 ± 0.065	1.863ValLys: 1.863 ± 0.042	7.11ValLeu: 7.11 ± 0.094	1.78ValMet: 1.78 ± 0.036	1.957ValAsn: 1.957 ± 0.042	3.932ValPro: 3.932 ± 0.052	2.019ValGln: 2.019 ± 0.039	4.76ValArg: 4.76 ± 0.063	4.295ValSer: 4.295 ± 0.062	4.366ValThr: 4.366 ± 0.072	5.323ValVal: 5.323 ± 0.069	0.903ValTrp: 0.903 ± 0.031	1.447ValTyr: 1.447 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.41TrpAla: 1.41 ± 0.035	0.152TrpCys: 0.152 ± 0.011	0.764TrpAsp: 0.764 ± 0.028	0.645TrpGlu: 0.645 ± 0.026	0.604TrpPhe: 0.604 ± 0.025	0.986TrpGly: 0.986 ± 0.028	0.363TrpHis: 0.363 ± 0.018	0.652TrpIle: 0.652 ± 0.022	0.438TrpLys: 0.438 ± 0.018	1.763TrpLeu: 1.763 ± 0.046	0.368TrpMet: 0.368 ± 0.018	0.449TrpAsn: 0.449 ± 0.023	0.718TrpPro: 0.718 ± 0.022	0.704TrpGln: 0.704 ± 0.023	1.313TrpArg: 1.313 ± 0.034	0.94TrpSer: 0.94 ± 0.027	0.747TrpThr: 0.747 ± 0.02	0.842TrpVal: 0.842 ± 0.029	0.228TrpTrp: 0.228 ± 0.014	0.304TrpTyr: 0.304 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.766TyrAla: 2.766 ± 0.051	0.259TyrCys: 0.259 ± 0.016	1.607TyrAsp: 1.607 ± 0.044	1.304TyrGlu: 1.304 ± 0.036	0.948TyrPhe: 0.948 ± 0.026	2.162TyrGly: 2.162 ± 0.045	0.48TyrHis: 0.48 ± 0.019	0.898TyrIle: 0.898 ± 0.025	0.537TyrLys: 0.537 ± 0.021	2.186TyrLeu: 2.186 ± 0.047	0.421TyrMet: 0.421 ± 0.017	0.68TyrAsn: 0.68 ± 0.026	1.086TyrPro: 1.086 ± 0.031	0.702TyrGln: 0.702 ± 0.025	1.939TyrArg: 1.939 ± 0.043	1.306TyrSer: 1.306 ± 0.033	1.195TyrThr: 1.195 ± 0.037	1.623TyrVal: 1.623 ± 0.044	0.363TyrTrp: 0.363 ± 0.018	0.699TyrTyr: 0.699 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3955 proteins (1287496 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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