Amino acid dipepetide frequency for Mobilicoccus pelagius NBRC 104925

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.411AlaAla: 19.411 ± 0.222	1.106AlaCys: 1.106 ± 0.034	8.551AlaAsp: 8.551 ± 0.1	7.912AlaGlu: 7.912 ± 0.119	3.449AlaPhe: 3.449 ± 0.063	12.458AlaGly: 12.458 ± 0.132	3.017AlaHis: 3.017 ± 0.056	4.111AlaIle: 4.111 ± 0.073	2.55AlaLys: 2.55 ± 0.066	13.199AlaLeu: 13.199 ± 0.141	2.811AlaMet: 2.811 ± 0.053	1.83AlaAsn: 1.83 ± 0.049	7.433AlaPro: 7.433 ± 0.145	3.441AlaGln: 3.441 ± 0.06	10.625AlaArg: 10.625 ± 0.13	6.689AlaSer: 6.689 ± 0.084	8.144AlaThr: 8.144 ± 0.117	11.453AlaVal: 11.453 ± 0.124	1.883AlaTrp: 1.883 ± 0.045	2.268AlaTyr: 2.268 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.947CysAla: 0.947 ± 0.031	0.102CysCys: 0.102 ± 0.011	0.458CysAsp: 0.458 ± 0.022	0.416CysGlu: 0.416 ± 0.02	0.198CysPhe: 0.198 ± 0.014	0.969CysGly: 0.969 ± 0.03	0.195CysHis: 0.195 ± 0.016	0.21CysIle: 0.21 ± 0.013	0.099CysLys: 0.099 ± 0.011	0.745CysLeu: 0.745 ± 0.03	0.113CysMet: 0.113 ± 0.009	0.108CysAsn: 0.108 ± 0.011	0.51CysPro: 0.51 ± 0.024	0.137CysGln: 0.137 ± 0.011	0.633CysArg: 0.633 ± 0.027	0.426CysSer: 0.426 ± 0.021	0.489CysThr: 0.489 ± 0.02	0.683CysVal: 0.683 ± 0.026	0.098CysTrp: 0.098 ± 0.01	0.134CysTyr: 0.134 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	9.276AspAla: 9.276 ± 0.103	0.355AspCys: 0.355 ± 0.02	5.057AspAsp: 5.057 ± 0.084	4.491AspGlu: 4.491 ± 0.086	1.316AspPhe: 1.316 ± 0.039	6.137AspGly: 6.137 ± 0.083	1.531AspHis: 1.531 ± 0.041	1.846AspIle: 1.846 ± 0.051	1.009AspLys: 1.009 ± 0.038	7.248AspLeu: 7.248 ± 0.1	1.009AspMet: 1.009 ± 0.032	0.739AspAsn: 0.739 ± 0.028	4.826AspPro: 4.826 ± 0.075	1.227AspGln: 1.227 ± 0.037	5.02AspArg: 5.02 ± 0.092	2.409AspSer: 2.409 ± 0.053	3.391AspThr: 3.391 ± 0.06	6.765AspVal: 6.765 ± 0.089	0.769AspTrp: 0.769 ± 0.028	1.037AspTyr: 1.037 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	7.787GluAla: 7.787 ± 0.118	0.391GluCys: 0.391 ± 0.017	3.407GluAsp: 3.407 ± 0.055	3.856GluGlu: 3.856 ± 0.075	1.581GluPhe: 1.581 ± 0.039	4.681GluGly: 4.681 ± 0.079	1.608GluHis: 1.608 ± 0.041	2.664GluIle: 2.664 ± 0.057	1.596GluLys: 1.596 ± 0.049	5.327GluLeu: 5.327 ± 0.077	1.113GluMet: 1.113 ± 0.032	1.162GluAsn: 1.162 ± 0.04	2.923GluPro: 2.923 ± 0.055	1.888GluGln: 1.888 ± 0.051	5.166GluArg: 5.166 ± 0.078	2.775GluSer: 2.775 ± 0.046	3.15GluThr: 3.15 ± 0.053	5.129GluVal: 5.129 ± 0.082	0.754GluTrp: 0.754 ± 0.027	1.063GluTyr: 1.063 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.422PheAla: 3.422 ± 0.057	0.275PheCys: 0.275 ± 0.017	1.983PheAsp: 1.983 ± 0.053	1.426PheGlu: 1.426 ± 0.037	0.901PhePhe: 0.901 ± 0.032	2.947PheGly: 2.947 ± 0.059	0.609PheHis: 0.609 ± 0.028	0.676PheIle: 0.676 ± 0.03	0.389PheLys: 0.389 ± 0.021	2.467PheLeu: 2.467 ± 0.055	0.438PheMet: 0.438 ± 0.023	0.443PheAsn: 0.443 ± 0.021	1.269PhePro: 1.269 ± 0.037	0.492PheGln: 0.492 ± 0.02	1.623PheArg: 1.623 ± 0.039	1.421PheSer: 1.421 ± 0.037	1.86PheThr: 1.86 ± 0.044	2.77PheVal: 2.77 ± 0.054	0.36PheTrp: 0.36 ± 0.021	0.576PheTyr: 0.576 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	11.092GlyAla: 11.092 ± 0.121	0.807GlyCys: 0.807 ± 0.026	5.714GlyAsp: 5.714 ± 0.093	5.395GlyGlu: 5.395 ± 0.077	2.702GlyPhe: 2.702 ± 0.05	8.687GlyGly: 8.687 ± 0.112	2.334GlyHis: 2.334 ± 0.048	3.632GlyIle: 3.632 ± 0.074	2.021GlyLys: 2.021 ± 0.047	9.284GlyLeu: 9.284 ± 0.111	2.107GlyMet: 2.107 ± 0.046	1.443GlyAsn: 1.443 ± 0.045	4.72GlyPro: 4.72 ± 0.072	2.263GlyGln: 2.263 ± 0.056	8.313GlyArg: 8.313 ± 0.098	5.02GlySer: 5.02 ± 0.074	6.004GlyThr: 6.004 ± 0.084	8.508GlyVal: 8.508 ± 0.105	1.567GlyTrp: 1.567 ± 0.043	2.039GlyTyr: 2.039 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.804HisAla: 2.804 ± 0.046	0.184HisCys: 0.184 ± 0.014	1.787HisAsp: 1.787 ± 0.046	1.481HisGlu: 1.481 ± 0.037	0.492HisPhe: 0.492 ± 0.021	2.375HisGly: 2.375 ± 0.052	0.72HisHis: 0.72 ± 0.026	0.575HisIle: 0.575 ± 0.026	0.285HisLys: 0.285 ± 0.016	2.653HisLeu: 2.653 ± 0.054	0.356HisMet: 0.356 ± 0.019	0.314HisAsn: 0.314 ± 0.017	1.813HisPro: 1.813 ± 0.036	0.471HisGln: 0.471 ± 0.022	2.085HisArg: 2.085 ± 0.048	0.845HisSer: 0.845 ± 0.03	1.281HisThr: 1.281 ± 0.036	2.351HisVal: 2.351 ± 0.048	0.261HisTrp: 0.261 ± 0.015	0.387HisTyr: 0.387 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	4.761IleAla: 4.761 ± 0.074	0.302IleCys: 0.302 ± 0.018	2.598IleAsp: 2.598 ± 0.052	2.1IleGlu: 2.1 ± 0.046	0.735IlePhe: 0.735 ± 0.03	3.469IleGly: 3.469 ± 0.083	0.653IleHis: 0.653 ± 0.023	0.956IleIle: 0.956 ± 0.037	0.626IleLys: 0.626 ± 0.028	2.862IleLeu: 2.862 ± 0.059	0.522IleMet: 0.522 ± 0.022	0.613IleAsn: 0.613 ± 0.024	1.893IlePro: 1.893 ± 0.046	0.601IleGln: 0.601 ± 0.024	2.257IleArg: 2.257 ± 0.05	1.529IleSer: 1.529 ± 0.04	2.187IleThr: 2.187 ± 0.054	3.383IleVal: 3.383 ± 0.072	0.314IleTrp: 0.314 ± 0.02	0.547IleTyr: 0.547 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.57LysAla: 2.57 ± 0.067	0.091LysCys: 0.091 ± 0.009	1.233LysAsp: 1.233 ± 0.044	1.053LysGlu: 1.053 ± 0.037	0.44LysPhe: 0.44 ± 0.022	1.744LysGly: 1.744 ± 0.049	0.384LysHis: 0.384 ± 0.021	0.802LysIle: 0.802 ± 0.031	0.802LysLys: 0.802 ± 0.041	1.409LysLeu: 1.409 ± 0.043	0.386LysMet: 0.386 ± 0.018	0.518LysAsn: 0.518 ± 0.026	1.048LysPro: 1.048 ± 0.045	0.555LysGln: 0.555 ± 0.024	1.281LysArg: 1.281 ± 0.042	0.966LysSer: 0.966 ± 0.032	1.213LysThr: 1.213 ± 0.041	1.724LysVal: 1.724 ± 0.047	0.188LysTrp: 0.188 ± 0.014	0.386LysTyr: 0.386 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	14.414LeuAla: 14.414 ± 0.164	0.648LeuCys: 0.648 ± 0.027	7.243LeuAsp: 7.243 ± 0.097	4.787LeuGlu: 4.787 ± 0.085	2.446LeuPhe: 2.446 ± 0.055	9.342LeuGly: 9.342 ± 0.104	2.195LeuHis: 2.195 ± 0.046	2.288LeuIle: 2.288 ± 0.061	1.484LeuLys: 1.484 ± 0.05	10.348LeuLeu: 10.348 ± 0.142	1.564LeuMet: 1.564 ± 0.041	1.258LeuAsn: 1.258 ± 0.037	5.841LeuPro: 5.841 ± 0.092	2.067LeuGln: 2.067 ± 0.048	7.881LeuArg: 7.881 ± 0.095	4.643LeuSer: 4.643 ± 0.073	6.756LeuThr: 6.756 ± 0.084	10.541LeuVal: 10.541 ± 0.14	1.127LeuTrp: 1.127 ± 0.038	1.486LeuTyr: 1.486 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.193MetAla: 2.193 ± 0.05	0.157MetCys: 0.157 ± 0.011	0.912MetAsp: 0.912 ± 0.031	0.791MetGlu: 0.791 ± 0.03	0.58MetPhe: 0.58 ± 0.022	1.525MetGly: 1.525 ± 0.038	0.357MetHis: 0.357 ± 0.02	0.792MetIle: 0.792 ± 0.029	0.454MetLys: 0.454 ± 0.024	1.912MetLeu: 1.912 ± 0.043	0.331MetMet: 0.331 ± 0.019	0.468MetAsn: 0.468 ± 0.023	1.306MetPro: 1.306 ± 0.036	0.495MetGln: 0.495 ± 0.023	1.703MetArg: 1.703 ± 0.043	1.596MetSer: 1.596 ± 0.037	1.855MetThr: 1.855 ± 0.041	1.264MetVal: 1.264 ± 0.039	0.264MetTrp: 0.264 ± 0.016	0.291MetTyr: 0.291 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.013AsnAla: 2.013 ± 0.046	0.113AsnCys: 0.113 ± 0.01	0.99AsnAsp: 0.99 ± 0.034	0.782AsnGlu: 0.782 ± 0.031	0.369AsnPhe: 0.369 ± 0.021	1.504AsnGly: 1.504 ± 0.039	0.358AsnHis: 0.358 ± 0.017	0.582AsnIle: 0.582 ± 0.025	0.336AsnLys: 0.336 ± 0.018	1.559AsnLeu: 1.559 ± 0.036	0.288AsnMet: 0.288 ± 0.018	0.326AsnAsn: 0.326 ± 0.02	1.378AsnPro: 1.378 ± 0.041	0.383AsnGln: 0.383 ± 0.023	1.086AsnArg: 1.086 ± 0.033	0.781AsnSer: 0.781 ± 0.031	1.0AsnThr: 1.0 ± 0.032	1.435AsnVal: 1.435 ± 0.038	0.201AsnTrp: 0.201 ± 0.013	0.321AsnTyr: 0.321 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	8.157ProAla: 8.157 ± 0.119	0.351ProCys: 0.351 ± 0.017	4.218ProAsp: 4.218 ± 0.068	4.274ProGlu: 4.274 ± 0.059	1.506ProPhe: 1.506 ± 0.035	6.366ProGly: 6.366 ± 0.085	1.521ProHis: 1.521 ± 0.044	1.63ProIle: 1.63 ± 0.042	1.038ProLys: 1.038 ± 0.038	4.913ProLeu: 4.913 ± 0.085	1.181ProMet: 1.181 ± 0.033	0.833ProAsn: 0.833 ± 0.029	3.296ProPro: 3.296 ± 0.072	1.586ProGln: 1.586 ± 0.048	4.433ProArg: 4.433 ± 0.076	3.372ProSer: 3.372 ± 0.059	4.363ProThr: 4.363 ± 0.086	5.448ProVal: 5.448 ± 0.096	0.966ProTrp: 0.966 ± 0.035	1.09ProTyr: 1.09 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.305GlnAla: 3.305 ± 0.062	0.145GlnCys: 0.145 ± 0.01	1.196GlnAsp: 1.196 ± 0.036	1.29GlnGlu: 1.29 ± 0.035	0.613GlnPhe: 0.613 ± 0.025	2.085GlnGly: 2.085 ± 0.047	0.54GlnHis: 0.54 ± 0.025	1.217GlnIle: 1.217 ± 0.034	0.562GlnLys: 0.562 ± 0.025	2.252GlnLeu: 2.252 ± 0.068	0.561GlnMet: 0.561 ± 0.023	0.463GlnAsn: 0.463 ± 0.021	1.213GlnPro: 1.213 ± 0.034	0.856GlnGln: 0.856 ± 0.039	2.064GlnArg: 2.064 ± 0.055	1.012GlnSer: 1.012 ± 0.033	1.253GlnThr: 1.253 ± 0.038	2.293GlnVal: 2.293 ± 0.05	0.38GlnTrp: 0.38 ± 0.018	0.489GlnTyr: 0.489 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	9.6ArgAla: 9.6 ± 0.115	0.638ArgCys: 0.638 ± 0.026	4.655ArgAsp: 4.655 ± 0.081	4.833ArgGlu: 4.833 ± 0.08	2.206ArgPhe: 2.206 ± 0.042	6.419ArgGly: 6.419 ± 0.1	2.221ArgHis: 2.221 ± 0.042	3.251ArgIle: 3.251 ± 0.055	1.314ArgLys: 1.314 ± 0.042	8.445ArgLeu: 8.445 ± 0.109	1.953ArgMet: 1.953 ± 0.044	1.225ArgAsn: 1.225 ± 0.039	5.278ArgPro: 5.278 ± 0.092	1.937ArgGln: 1.937 ± 0.047	8.947ArgArg: 8.947 ± 0.14	4.101ArgSer: 4.101 ± 0.066	5.166ArgThr: 5.166 ± 0.071	6.501ArgVal: 6.501 ± 0.089	1.28ArgTrp: 1.28 ± 0.037	1.608ArgTyr: 1.608 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.35SerAla: 6.35 ± 0.075	0.423SerCys: 0.423 ± 0.02	2.843SerAsp: 2.843 ± 0.052	2.403SerGlu: 2.403 ± 0.049	1.545SerPhe: 1.545 ± 0.038	5.455SerGly: 5.455 ± 0.076	1.029SerHis: 1.029 ± 0.03	1.763SerIle: 1.763 ± 0.039	0.876SerLys: 0.876 ± 0.031	4.629SerLeu: 4.629 ± 0.069	1.215SerMet: 1.215 ± 0.034	0.796SerAsn: 0.796 ± 0.027	3.396SerPro: 3.396 ± 0.07	1.121SerGln: 1.121 ± 0.029	4.033SerArg: 4.033 ± 0.058	3.031SerSer: 3.031 ± 0.076	3.816SerThr: 3.816 ± 0.072	4.136SerVal: 4.136 ± 0.062	0.858SerTrp: 0.858 ± 0.03	1.041SerTyr: 1.041 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	7.984ThrAla: 7.984 ± 0.113	0.528ThrCys: 0.528 ± 0.03	3.937ThrAsp: 3.937 ± 0.071	3.122ThrGlu: 3.122 ± 0.056	1.799ThrPhe: 1.799 ± 0.043	6.423ThrGly: 6.423 ± 0.081	1.477ThrHis: 1.477 ± 0.037	2.288ThrIle: 2.288 ± 0.048	1.198ThrLys: 1.198 ± 0.041	5.908ThrLeu: 5.908 ± 0.076	1.133ThrMet: 1.133 ± 0.036	1.135ThrAsn: 1.135 ± 0.035	5.202ThrPro: 5.202 ± 0.084	1.48ThrGln: 1.48 ± 0.034	4.639ThrArg: 4.639 ± 0.079	3.894ThrSer: 3.894 ± 0.07	4.988ThrThr: 4.988 ± 0.098	5.466ThrVal: 5.466 ± 0.086	1.036ThrTrp: 1.036 ± 0.035	1.392ThrTyr: 1.392 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	12.406ValAla: 12.406 ± 0.136	0.74ValCys: 0.74 ± 0.028	6.646ValAsp: 6.646 ± 0.078	5.862ValGlu: 5.862 ± 0.08	2.433ValPhe: 2.433 ± 0.057	8.101ValGly: 8.101 ± 0.097	2.082ValHis: 2.082 ± 0.048	2.589ValIle: 2.589 ± 0.059	1.537ValLys: 1.537 ± 0.04	9.77ValLeu: 9.77 ± 0.13	1.579ValMet: 1.579 ± 0.045	1.451ValAsn: 1.451 ± 0.037	5.464ValPro: 5.464 ± 0.084	1.912ValGln: 1.912 ± 0.047	6.898ValArg: 6.898 ± 0.077	4.547ValSer: 4.547 ± 0.07	6.162ValThr: 6.162 ± 0.087	11.068ValVal: 11.068 ± 0.127	1.14ValTrp: 1.14 ± 0.038	1.437ValTyr: 1.437 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.577TrpAla: 1.577 ± 0.044	0.161TrpCys: 0.161 ± 0.013	0.681TrpAsp: 0.681 ± 0.024	0.67TrpGlu: 0.67 ± 0.027	0.517TrpPhe: 0.517 ± 0.025	1.079TrpGly: 1.079 ± 0.038	0.344TrpHis: 0.344 ± 0.017	0.58TrpIle: 0.58 ± 0.026	0.307TrpLys: 0.307 ± 0.019	1.508TrpLeu: 1.508 ± 0.041	0.344TrpMet: 0.344 ± 0.016	0.352TrpAsn: 0.352 ± 0.022	0.725TrpPro: 0.725 ± 0.03	0.455TrpGln: 0.455 ± 0.022	1.311TrpArg: 1.311 ± 0.037	0.854TrpSer: 0.854 ± 0.031	0.892TrpThr: 0.892 ± 0.032	1.101TrpVal: 1.101 ± 0.039	0.404TrpTrp: 0.404 ± 0.024	0.255TrpTyr: 0.255 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.274TyrAla: 2.274 ± 0.054	0.153TyrCys: 0.153 ± 0.012	1.351TyrAsp: 1.351 ± 0.04	1.076TyrGlu: 1.076 ± 0.036	0.519TyrPhe: 0.519 ± 0.022	1.885TyrGly: 1.885 ± 0.044	0.343TyrHis: 0.343 ± 0.019	0.457TyrIle: 0.457 ± 0.023	0.313TyrLys: 0.313 ± 0.018	1.92TyrLeu: 1.92 ± 0.043	0.239TyrMet: 0.239 ± 0.017	0.329TyrAsn: 0.329 ± 0.017	1.008TyrPro: 1.008 ± 0.03	0.425TyrGln: 0.425 ± 0.021	1.58TyrArg: 1.58 ± 0.042	0.849TyrSer: 0.849 ± 0.031	1.057TyrThr: 1.057 ± 0.036	1.805TyrVal: 1.805 ± 0.045	0.263TyrTrp: 0.263 ± 0.015	0.382TyrTyr: 0.382 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3112 proteins (1040358 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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