Amino acid dipepetide frequency for Changping Tick Virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.44AlaAla: 9.44 ± 4.223
3.654AlaCys: 3.654 ± 0.469
3.654AlaAsp: 3.654 ± 0.795
5.786AlaGlu: 5.786 ± 0.481
2.132AlaPhe: 2.132 ± 0.916
6.09AlaGly: 6.09 ± 2.082
2.132AlaHis: 2.132 ± 0.242
4.263AlaIle: 4.263 ± 1.913
4.263AlaLys: 4.263 ± 0.71
8.222AlaLeu: 8.222 ± 1.42
0.609AlaMet: 0.609 ± 0.337
2.132AlaAsn: 2.132 ± 1.279
3.654AlaPro: 3.654 ± 1.2
3.959AlaGln: 3.959 ± 0.746
4.263AlaArg: 4.263 ± 1.913
4.568AlaSer: 4.568 ± 1.143
3.654AlaThr: 3.654 ± 0.436
7.308AlaVal: 7.308 ± 1.177
2.132AlaTrp: 2.132 ± 1.932
3.654AlaTyr: 3.654 ± 1.061
0.0AlaXaa: 0.0 ± 0.0
Cys
1.827CysAla: 1.827 ± 0.606
0.0CysCys: 0.0 ± 0.0
1.523CysAsp: 1.523 ± 0.466
0.914CysGlu: 0.914 ± 0.767
0.609CysPhe: 0.609 ± 0.341
1.523CysGly: 1.523 ± 0.615
0.914CysHis: 0.914 ± 0.3
0.609CysIle: 0.609 ± 0.341
0.914CysLys: 0.914 ± 0.511
3.045CysLeu: 3.045 ± 1.048
0.609CysMet: 0.609 ± 0.341
0.305CysAsn: 0.305 ± 0.17
1.218CysPro: 1.218 ± 0.674
0.609CysGln: 0.609 ± 0.341
2.132CysArg: 2.132 ± 0.633
0.914CysSer: 0.914 ± 0.767
0.914CysThr: 0.914 ± 0.511
0.609CysVal: 0.609 ± 0.341
0.305CysTrp: 0.305 ± 0.442
1.523CysTyr: 1.523 ± 0.615
0.0CysXaa: 0.0 ± 0.0
Asp
3.959AspAla: 3.959 ± 1.029
1.218AspCys: 1.218 ± 1.206
1.218AspAsp: 1.218 ± 0.681
2.741AspGlu: 2.741 ± 1.023
0.914AspPhe: 0.914 ± 0.511
2.436AspGly: 2.436 ± 0.918
1.523AspHis: 1.523 ± 0.466
2.741AspIle: 2.741 ± 0.946
1.523AspLys: 1.523 ± 0.561
8.222AspLeu: 8.222 ± 2.256
0.914AspMet: 0.914 ± 0.435
1.827AspAsn: 1.827 ± 0.606
2.436AspPro: 2.436 ± 1.181
1.218AspGln: 1.218 ± 0.353
3.654AspArg: 3.654 ± 2.125
3.045AspSer: 3.045 ± 0.932
1.827AspThr: 1.827 ± 1.022
3.35AspVal: 3.35 ± 1.411
1.218AspTrp: 1.218 ± 0.472
1.218AspTyr: 1.218 ± 0.472
0.0AspXaa: 0.0 ± 0.0
Glu
6.09GluAla: 6.09 ± 0.841
0.914GluCys: 0.914 ± 0.511
2.741GluAsp: 2.741 ± 1.304
3.959GluGlu: 3.959 ± 0.922
1.827GluPhe: 1.827 ± 0.736
6.395GluGly: 6.395 ± 3.298
1.827GluHis: 1.827 ± 0.138
4.568GluIle: 4.568 ± 0.632
3.35GluLys: 3.35 ± 1.874
6.395GluLeu: 6.395 ± 0.688
1.523GluMet: 1.523 ± 0.656
2.132GluAsn: 2.132 ± 0.242
2.436GluPro: 2.436 ± 1.929
1.827GluGln: 1.827 ± 0.869
4.872GluArg: 4.872 ± 0.804
1.523GluSer: 1.523 ± 0.194
3.654GluThr: 3.654 ± 0.469
3.654GluVal: 3.654 ± 0.795
0.305GluTrp: 0.305 ± 0.543
0.609GluTyr: 0.609 ± 0.337
0.0GluXaa: 0.0 ± 0.0
Phe
2.741PheAla: 2.741 ± 0.571
0.609PheCys: 0.609 ± 0.341
1.523PheAsp: 1.523 ± 0.466
2.132PheGlu: 2.132 ± 0.242
1.523PhePhe: 1.523 ± 0.194
2.741PheGly: 2.741 ± 0.9
1.827PheHis: 1.827 ± 1.011
2.741PheIle: 2.741 ± 0.809
1.218PheLys: 1.218 ± 0.353
3.35PheLeu: 3.35 ± 1.068
0.0PheMet: 0.0 ± 0.0
1.218PheAsn: 1.218 ± 0.681
1.523PhePro: 1.523 ± 0.854
1.827PheGln: 1.827 ± 1.385
5.177PheArg: 5.177 ± 0.339
2.741PheSer: 2.741 ± 0.171
1.827PheThr: 1.827 ± 0.736
2.436PheVal: 2.436 ± 1.348
0.914PheTrp: 0.914 ± 0.511
0.914PheTyr: 0.914 ± 0.3
0.0PheXaa: 0.0 ± 0.0
Gly
4.263GlyAla: 4.263 ± 0.716
0.305GlyCys: 0.305 ± 0.17
2.436GlyAsp: 2.436 ± 1.309
3.654GlyGlu: 3.654 ± 1.059
4.568GlyPhe: 4.568 ± 0.583
4.263GlyGly: 4.263 ± 1.373
1.827GlyHis: 1.827 ± 0.6
3.35GlyIle: 3.35 ± 0.421
1.827GlyLys: 1.827 ± 0.606
9.44GlyLeu: 9.44 ± 1.272
0.914GlyMet: 0.914 ± 0.792
1.218GlyAsn: 1.218 ± 0.472
0.609GlyPro: 0.609 ± 0.341
1.523GlyGln: 1.523 ± 0.88
3.959GlyArg: 3.959 ± 1.029
4.568GlySer: 4.568 ± 2.179
3.35GlyThr: 3.35 ± 0.477
6.09GlyVal: 6.09 ± 0.778
2.436GlyTrp: 2.436 ± 1.117
3.35GlyTyr: 3.35 ± 0.421
0.0GlyXaa: 0.0 ± 0.0
His
2.741HisAla: 2.741 ± 0.9
0.305HisCys: 0.305 ± 0.442
0.609HisAsp: 0.609 ± 0.341
1.523HisGlu: 1.523 ± 0.466
0.914HisPhe: 0.914 ± 0.767
0.914HisGly: 0.914 ± 0.3
1.218HisHis: 1.218 ± 0.674
1.523HisIle: 1.523 ± 0.656
0.609HisLys: 0.609 ± 0.341
2.132HisLeu: 2.132 ± 1.279
1.523HisMet: 1.523 ± 0.466
0.914HisAsn: 0.914 ± 0.511
2.741HisPro: 2.741 ± 0.646
1.827HisGln: 1.827 ± 0.6
1.523HisArg: 1.523 ± 0.852
1.523HisSer: 1.523 ± 0.466
2.436HisThr: 2.436 ± 1.348
3.35HisVal: 3.35 ± 1.203
0.609HisTrp: 0.609 ± 0.665
1.218HisTyr: 1.218 ± 0.353
0.0HisXaa: 0.0 ± 0.0
Ile
3.654IleAla: 3.654 ± 0.436
0.609IleCys: 0.609 ± 0.462
1.827IleAsp: 1.827 ± 0.682
3.35IleGlu: 3.35 ± 1.01
2.741IlePhe: 2.741 ± 1.279
2.436IleGly: 2.436 ± 0.395
0.914IleHis: 0.914 ± 0.511
1.523IleIle: 1.523 ± 0.466
2.132IleLys: 2.132 ± 0.82
5.177IleLeu: 5.177 ± 0.584
0.914IleMet: 0.914 ± 0.511
0.914IleAsn: 0.914 ± 0.499
1.523IlePro: 1.523 ± 0.88
2.436IleGln: 2.436 ± 0.395
3.35IleArg: 3.35 ± 1.237
3.045IleSer: 3.045 ± 0.724
5.481IleThr: 5.481 ± 0.921
1.827IleVal: 1.827 ± 0.869
0.609IleTrp: 0.609 ± 0.341
0.914IleTyr: 0.914 ± 0.3
0.0IleXaa: 0.0 ± 0.0
Lys
3.35LysAla: 3.35 ± 0.606
0.609LysCys: 0.609 ± 0.341
2.741LysAsp: 2.741 ± 1.533
2.741LysGlu: 2.741 ± 0.571
2.132LysPhe: 2.132 ± 0.82
3.654LysGly: 3.654 ± 0.795
1.218LysHis: 1.218 ± 0.681
1.827LysIle: 1.827 ± 0.606
2.132LysLys: 2.132 ± 0.82
4.568LysLeu: 4.568 ± 0.533
0.914LysMet: 0.914 ± 0.499
1.218LysAsn: 1.218 ± 0.472
1.827LysPro: 1.827 ± 0.606
1.218LysGln: 1.218 ± 0.353
1.218LysArg: 1.218 ± 0.681
1.218LysSer: 1.218 ± 0.681
1.523LysThr: 1.523 ± 0.466
3.959LysVal: 3.959 ± 1.23
0.305LysTrp: 0.305 ± 0.17
2.132LysTyr: 2.132 ± 0.633
0.0LysXaa: 0.0 ± 0.0
Leu
7.613LeuAla: 7.613 ± 0.994
3.35LeuCys: 3.35 ± 1.411
6.395LeuAsp: 6.395 ± 1.099
6.395LeuGlu: 6.395 ± 1.303
5.786LeuPhe: 5.786 ± 0.758
8.222LeuGly: 8.222 ± 1.237
4.263LeuHis: 4.263 ± 1.272
3.654LeuIle: 3.654 ± 1.005
3.959LeuLys: 3.959 ± 1.745
11.876LeuLeu: 11.876 ± 0.959
2.436LeuMet: 2.436 ± 0.774
3.959LeuAsn: 3.959 ± 1.512
6.699LeuPro: 6.699 ± 0.293
5.786LeuGln: 5.786 ± 1.078
6.09LeuArg: 6.09 ± 2.084
6.09LeuSer: 6.09 ± 0.929
6.09LeuThr: 6.09 ± 0.592
8.831LeuVal: 8.831 ± 0.795
1.218LeuTrp: 1.218 ± 0.472
3.654LeuTyr: 3.654 ± 1.412
0.0LeuXaa: 0.0 ± 0.0
Met
2.132MetAla: 2.132 ± 1.287
0.609MetCys: 0.609 ± 0.337
1.218MetAsp: 1.218 ± 0.681
1.218MetGlu: 1.218 ± 0.681
1.827MetPhe: 1.827 ± 0.999
1.827MetGly: 1.827 ± 0.6
0.914MetHis: 0.914 ± 0.99
0.914MetIle: 0.914 ± 0.435
1.218MetLys: 1.218 ± 0.674
1.218MetLeu: 1.218 ± 0.353
0.305MetMet: 0.305 ± 0.543
0.305MetAsn: 0.305 ± 0.17
0.609MetPro: 0.609 ± 0.341
0.609MetGln: 0.609 ± 0.341
0.914MetArg: 0.914 ± 0.499
2.132MetSer: 2.132 ± 1.434
2.132MetThr: 2.132 ± 0.242
0.609MetVal: 0.609 ± 0.341
0.305MetTrp: 0.305 ± 0.17
0.609MetTyr: 0.609 ± 0.884
0.0MetXaa: 0.0 ± 0.0
Asn
3.35AsnAla: 3.35 ± 0.687
0.305AsnCys: 0.305 ± 0.442
0.914AsnAsp: 0.914 ± 0.435
0.609AsnGlu: 0.609 ± 0.341
2.132AsnPhe: 2.132 ± 0.82
0.609AsnGly: 0.609 ± 0.337
0.914AsnHis: 0.914 ± 0.767
1.218AsnIle: 1.218 ± 0.353
0.609AsnLys: 0.609 ± 0.341
3.045AsnLeu: 3.045 ± 0.389
0.305AsnMet: 0.305 ± 0.17
0.914AsnAsn: 0.914 ± 0.511
1.523AsnPro: 1.523 ± 0.466
1.827AsnGln: 1.827 ± 1.385
3.654AsnArg: 3.654 ± 0.795
1.523AsnSer: 1.523 ± 0.194
1.523AsnThr: 1.523 ± 0.194
2.436AsnVal: 2.436 ± 0.583
0.305AsnTrp: 0.305 ± 0.17
0.914AsnTyr: 0.914 ± 0.3
0.0AsnXaa: 0.0 ± 0.0
Pro
3.35ProAla: 3.35 ± 1.01
0.914ProCys: 0.914 ± 1.326
4.263ProAsp: 4.263 ± 1.4
3.045ProGlu: 3.045 ± 0.724
2.436ProPhe: 2.436 ± 1.363
3.045ProGly: 3.045 ± 2.802
0.914ProHis: 0.914 ± 0.99
2.132ProIle: 2.132 ± 0.82
0.914ProLys: 0.914 ± 0.3
7.004ProLeu: 7.004 ± 1.424
0.609ProMet: 0.609 ± 0.277
1.827ProAsn: 1.827 ± 0.606
4.263ProPro: 4.263 ± 1.272
2.132ProGln: 2.132 ± 1.279
2.436ProArg: 2.436 ± 0.677
3.045ProSer: 3.045 ± 0.724
2.436ProThr: 2.436 ± 1.351
4.263ProVal: 4.263 ± 1.593
0.609ProTrp: 0.609 ± 0.462
2.132ProTyr: 2.132 ± 0.891
0.0ProXaa: 0.0 ± 0.0
Gln
4.568GlnAla: 4.568 ± 2.456
0.914GlnCys: 0.914 ± 0.511
2.132GlnAsp: 2.132 ± 0.642
3.35GlnGlu: 3.35 ± 1.174
0.609GlnPhe: 0.609 ± 0.337
2.132GlnGly: 2.132 ± 0.891
1.218GlnHis: 1.218 ± 0.681
1.827GlnIle: 1.827 ± 0.606
1.218GlnLys: 1.218 ± 0.681
4.872GlnLeu: 4.872 ± 1.25
0.609GlnMet: 0.609 ± 0.341
0.305GlnAsn: 0.305 ± 0.543
2.741GlnPro: 2.741 ± 1.796
2.436GlnGln: 2.436 ± 0.395
1.523GlnArg: 1.523 ± 0.466
0.914GlnSer: 0.914 ± 0.3
2.436GlnThr: 2.436 ± 1.351
3.045GlnVal: 3.045 ± 1.635
0.914GlnTrp: 0.914 ± 0.511
1.523GlnTyr: 1.523 ± 0.561
0.0GlnXaa: 0.0 ± 0.0
Arg
6.09ArgAla: 6.09 ± 1.083
1.218ArgCys: 1.218 ± 0.822
2.132ArgAsp: 2.132 ± 0.82
4.263ArgGlu: 4.263 ± 2.936
2.436ArgPhe: 2.436 ± 1.363
5.786ArgGly: 5.786 ± 1.033
2.436ArgHis: 2.436 ± 0.207
2.741ArgIle: 2.741 ± 0.558
3.045ArgLys: 3.045 ± 1.32
7.613ArgLeu: 7.613 ± 1.305
0.609ArgMet: 0.609 ± 0.884
0.914ArgAsn: 0.914 ± 0.499
2.741ArgPro: 2.741 ± 0.525
2.741ArgGln: 2.741 ± 0.571
5.177ArgArg: 5.177 ± 1.675
3.654ArgSer: 3.654 ± 1.2
3.35ArgThr: 3.35 ± 0.974
5.177ArgVal: 5.177 ± 1.961
1.827ArgTrp: 1.827 ± 0.682
1.827ArgTyr: 1.827 ± 0.682
0.0ArgXaa: 0.0 ± 0.0
Ser
3.959SerAla: 3.959 ± 1.95
0.914SerCys: 0.914 ± 0.511
2.436SerAsp: 2.436 ± 0.207
3.654SerGlu: 3.654 ± 0.276
3.959SerPhe: 3.959 ± 1.852
1.827SerGly: 1.827 ± 0.6
1.827SerHis: 1.827 ± 0.606
2.132SerIle: 2.132 ± 0.242
2.741SerLys: 2.741 ± 1.533
5.177SerLeu: 5.177 ± 0.339
0.914SerMet: 0.914 ± 0.511
1.218SerAsn: 1.218 ± 0.681
4.263SerPro: 4.263 ± 0.77
2.132SerGln: 2.132 ± 0.759
4.568SerArg: 4.568 ± 2.287
4.568SerSer: 4.568 ± 2.287
2.741SerThr: 2.741 ± 1.279
4.568SerVal: 4.568 ± 1.641
1.523SerTrp: 1.523 ± 0.561
3.654SerTyr: 3.654 ± 1.559
0.0SerXaa: 0.0 ± 0.0
Thr
3.959ThrAla: 3.959 ± 1.95
1.523ThrCys: 1.523 ± 0.615
2.436ThrAsp: 2.436 ± 1.348
3.045ThrGlu: 3.045 ± 1.042
0.914ThrPhe: 0.914 ± 0.3
1.827ThrGly: 1.827 ± 0.606
1.523ThrHis: 1.523 ± 0.615
3.045ThrIle: 3.045 ± 1.635
2.741ThrLys: 2.741 ± 1.215
8.222ThrLeu: 8.222 ± 1.569
2.436ThrMet: 2.436 ± 1.117
1.827ThrAsn: 1.827 ± 0.6
5.177ThrPro: 5.177 ± 1.585
1.827ThrGln: 1.827 ± 0.736
5.177ThrArg: 5.177 ± 1.496
3.654ThrSer: 3.654 ± 1.412
3.959ThrThr: 3.959 ± 0.828
4.568ThrVal: 4.568 ± 1.143
0.609ThrTrp: 0.609 ± 0.341
1.218ThrTyr: 1.218 ± 0.674
0.0ThrXaa: 0.0 ± 0.0
Val
10.353ValAla: 10.353 ± 1.55
2.132ValCys: 2.132 ± 0.759
3.045ValAsp: 3.045 ± 1.23
5.786ValGlu: 5.786 ± 0.481
0.914ValPhe: 0.914 ± 0.511
4.263ValGly: 4.263 ± 2.296
1.827ValHis: 1.827 ± 1.067
2.436ValIle: 2.436 ± 0.706
3.654ValLys: 3.654 ± 0.436
5.786ValLeu: 5.786 ± 1.757
3.045ValMet: 3.045 ± 0.893
2.436ValAsn: 2.436 ± 0.207
3.045ValPro: 3.045 ± 1.704
2.132ValGln: 2.132 ± 1.279
4.872ValArg: 4.872 ± 0.475
3.654ValSer: 3.654 ± 1.559
5.786ValThr: 5.786 ± 2.714
3.35ValVal: 3.35 ± 0.979
1.523ValTrp: 1.523 ± 0.194
3.045ValTyr: 3.045 ± 1.704
0.0ValXaa: 0.0 ± 0.0
Trp
0.609TrpAla: 0.609 ± 0.341
0.305TrpCys: 0.305 ± 0.17
1.523TrpAsp: 1.523 ± 1.514
1.218TrpGlu: 1.218 ± 0.472
0.0TrpPhe: 0.0 ± 0.0
0.914TrpGly: 0.914 ± 0.511
0.0TrpHis: 0.0 ± 0.0
1.218TrpIle: 1.218 ± 0.472
0.609TrpLys: 0.609 ± 0.341
2.741TrpLeu: 2.741 ± 0.571
0.914TrpMet: 0.914 ± 0.499
0.609TrpAsn: 0.609 ± 0.462
0.914TrpPro: 0.914 ± 0.435
0.609TrpGln: 0.609 ± 1.087
0.609TrpArg: 0.609 ± 0.462
3.045TrpSer: 3.045 ± 1.23
0.609TrpThr: 0.609 ± 0.337
0.914TrpVal: 0.914 ± 0.435
1.218TrpTrp: 1.218 ± 0.674
0.609TrpTyr: 0.609 ± 0.341
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.523TyrAla: 1.523 ± 0.561
0.609TyrCys: 0.609 ± 0.341
2.436TyrAsp: 2.436 ± 0.706
1.218TyrGlu: 1.218 ± 0.674
0.609TyrPhe: 0.609 ± 0.337
3.35TyrGly: 3.35 ± 0.421
0.914TyrHis: 0.914 ± 0.767
0.914TyrIle: 0.914 ± 0.435
1.827TyrLys: 1.827 ± 0.493
4.263TyrLeu: 4.263 ± 0.615
1.218TyrMet: 1.218 ± 0.674
2.436TyrAsn: 2.436 ± 0.918
1.827TyrPro: 1.827 ± 0.606
0.609TyrGln: 0.609 ± 0.337
0.609TyrArg: 0.609 ± 0.341
3.35TyrSer: 3.35 ± 1.068
3.959TyrThr: 3.959 ± 0.266
2.741TyrVal: 2.741 ± 0.558
0.305TyrTrp: 0.305 ± 0.442
1.827TyrTyr: 1.827 ± 0.138
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3285 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski