Amino acid dipepetide frequency for Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) (Bacillus tusciae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.971AlaAla: 11.971 ± 0.156	0.756AlaCys: 0.756 ± 0.03	4.982AlaAsp: 4.982 ± 0.083	6.729AlaGlu: 6.729 ± 0.096	3.452AlaPhe: 3.452 ± 0.065	9.556AlaGly: 9.556 ± 0.13	1.844AlaHis: 1.844 ± 0.044	4.459AlaIle: 4.459 ± 0.072	3.562AlaLys: 3.562 ± 0.065	10.917AlaLeu: 10.917 ± 0.145	2.618AlaMet: 2.618 ± 0.057	1.967AlaAsn: 1.967 ± 0.051	3.948AlaPro: 3.948 ± 0.073	3.239AlaGln: 3.239 ± 0.071	6.926AlaArg: 6.926 ± 0.107	4.443AlaSer: 4.443 ± 0.064	3.879AlaThr: 3.879 ± 0.069	9.849AlaVal: 9.849 ± 0.116	1.481AlaTrp: 1.481 ± 0.043	2.533AlaTyr: 2.533 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.655CysAla: 0.655 ± 0.027	0.098CysCys: 0.098 ± 0.011	0.417CysAsp: 0.417 ± 0.02	0.452CysGlu: 0.452 ± 0.021	0.258CysPhe: 0.258 ± 0.019	0.939CysGly: 0.939 ± 0.032	0.234CysHis: 0.234 ± 0.017	0.331CysIle: 0.331 ± 0.021	0.217CysLys: 0.217 ± 0.017	0.768CysLeu: 0.768 ± 0.026	0.143CysMet: 0.143 ± 0.013	0.2CysAsn: 0.2 ± 0.014	0.617CysPro: 0.617 ± 0.028	0.281CysGln: 0.281 ± 0.016	0.786CysArg: 0.786 ± 0.029	0.415CysSer: 0.415 ± 0.021	0.388CysThr: 0.388 ± 0.021	0.526CysVal: 0.526 ± 0.025	0.106CysTrp: 0.106 ± 0.011	0.229CysTyr: 0.229 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.513AspAla: 4.513 ± 0.077	0.305AspCys: 0.305 ± 0.018	2.316AspAsp: 2.316 ± 0.052	3.656AspGlu: 3.656 ± 0.071	1.797AspPhe: 1.797 ± 0.038	4.259AspGly: 4.259 ± 0.063	1.235AspHis: 1.235 ± 0.038	2.595AspIle: 2.595 ± 0.053	1.52AspLys: 1.52 ± 0.037	5.815AspLeu: 5.815 ± 0.08	1.078AspMet: 1.078 ± 0.038	0.981AspAsn: 0.981 ± 0.034	3.606AspPro: 3.606 ± 0.065	1.805AspGln: 1.805 ± 0.044	4.708AspArg: 4.708 ± 0.083	1.975AspSer: 1.975 ± 0.041	2.116AspThr: 2.116 ± 0.048	4.514AspVal: 4.514 ± 0.07	0.878AspTrp: 0.878 ± 0.029	1.392AspTyr: 1.392 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.123GluAla: 7.123 ± 0.11	0.362GluCys: 0.362 ± 0.018	3.518GluAsp: 3.518 ± 0.056	5.833GluGlu: 5.833 ± 0.107	1.88GluPhe: 1.88 ± 0.049	5.354GluGly: 5.354 ± 0.089	1.429GluHis: 1.429 ± 0.048	3.856GluIle: 3.856 ± 0.075	2.994GluLys: 2.994 ± 0.067	6.268GluLeu: 6.268 ± 0.091	1.862GluMet: 1.862 ± 0.038	1.645GluAsn: 1.645 ± 0.048	2.819GluPro: 2.819 ± 0.064	2.865GluGln: 2.865 ± 0.067	5.945GluArg: 5.945 ± 0.088	2.977GluSer: 2.977 ± 0.052	3.303GluThr: 3.303 ± 0.062	5.614GluVal: 5.614 ± 0.084	1.174GluTrp: 1.174 ± 0.042	1.588GluTyr: 1.588 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	3.341PheAla: 3.341 ± 0.066	0.365PheCys: 0.365 ± 0.021	1.945PheAsp: 1.945 ± 0.043	2.103PheGlu: 2.103 ± 0.047	1.364PhePhe: 1.364 ± 0.039	3.365PheGly: 3.365 ± 0.068	0.921PheHis: 0.921 ± 0.033	1.606PheIle: 1.606 ± 0.049	0.775PheLys: 0.775 ± 0.028	3.7PheLeu: 3.7 ± 0.078	0.716PheMet: 0.716 ± 0.028	0.784PheAsn: 0.784 ± 0.027	1.738PhePro: 1.738 ± 0.043	1.221PheGln: 1.221 ± 0.031	2.567PheArg: 2.567 ± 0.054	2.054PheSer: 2.054 ± 0.049	1.798PheThr: 1.798 ± 0.045	2.962PheVal: 2.962 ± 0.057	0.559PheTrp: 0.559 ± 0.028	1.076PheTyr: 1.076 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	8.045GlyAla: 8.045 ± 0.122	0.84GlyCys: 0.84 ± 0.034	4.259GlyAsp: 4.259 ± 0.066	5.357GlyGlu: 5.357 ± 0.088	3.15GlyPhe: 3.15 ± 0.067	7.444GlyGly: 7.444 ± 0.099	1.868GlyHis: 1.868 ± 0.043	5.004GlyIle: 5.004 ± 0.091	3.53GlyLys: 3.53 ± 0.067	8.658GlyLeu: 8.658 ± 0.102	2.56GlyMet: 2.56 ± 0.053	2.012GlyAsn: 2.012 ± 0.045	3.852GlyPro: 3.852 ± 0.062	3.146GlyGln: 3.146 ± 0.067	7.195GlyArg: 7.195 ± 0.099	4.546GlySer: 4.546 ± 0.082	4.804GlyThr: 4.804 ± 0.081	7.418GlyVal: 7.418 ± 0.109	1.724GlyTrp: 1.724 ± 0.048	2.624GlyTyr: 2.624 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.619HisAla: 1.619 ± 0.041	0.231HisCys: 0.231 ± 0.017	0.885HisAsp: 0.885 ± 0.03	1.089HisGlu: 1.089 ± 0.032	0.812HisPhe: 0.812 ± 0.027	1.868HisGly: 1.868 ± 0.049	0.682HisHis: 0.682 ± 0.033	1.018HisIle: 1.018 ± 0.027	0.583HisLys: 0.583 ± 0.025	2.545HisLeu: 2.545 ± 0.058	0.553HisMet: 0.553 ± 0.025	0.458HisAsn: 0.458 ± 0.024	1.785HisPro: 1.785 ± 0.045	0.728HisGln: 0.728 ± 0.03	2.123HisArg: 2.123 ± 0.057	0.997HisSer: 0.997 ± 0.032	1.001HisThr: 1.001 ± 0.031	1.859HisVal: 1.859 ± 0.045	0.394HisTrp: 0.394 ± 0.022	0.707HisTyr: 0.707 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.05IleAla: 5.05 ± 0.076	0.449IleCys: 0.449 ± 0.021	2.857IleAsp: 2.857 ± 0.066	3.177IleGlu: 3.177 ± 0.061	1.579IlePhe: 1.579 ± 0.037	4.6IleGly: 4.6 ± 0.078	1.352IleHis: 1.352 ± 0.038	2.0IleIle: 2.0 ± 0.053	1.324IleLys: 1.324 ± 0.044	5.318IleLeu: 5.318 ± 0.085	0.9IleMet: 0.9 ± 0.032	1.195IleAsn: 1.195 ± 0.04	3.134IlePro: 3.134 ± 0.062	1.974IleGln: 1.974 ± 0.053	4.302IleArg: 4.302 ± 0.078	2.528IleSer: 2.528 ± 0.057	2.503IleThr: 2.503 ± 0.054	4.095IleVal: 4.095 ± 0.077	0.623IleTrp: 0.623 ± 0.026	1.219IleTyr: 1.219 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.367LysAla: 3.367 ± 0.061	0.199LysCys: 0.199 ± 0.014	1.837LysAsp: 1.837 ± 0.045	2.774LysGlu: 2.774 ± 0.055	0.846LysPhe: 0.846 ± 0.032	2.976LysGly: 2.976 ± 0.057	0.604LysHis: 0.604 ± 0.027	1.888LysIle: 1.888 ± 0.052	1.728LysLys: 1.728 ± 0.049	2.814LysLeu: 2.814 ± 0.057	0.913LysMet: 0.913 ± 0.03	1.033LysAsn: 1.033 ± 0.036	1.757LysPro: 1.757 ± 0.05	1.325LysGln: 1.325 ± 0.04	2.746LysArg: 2.746 ± 0.058	1.642LysSer: 1.642 ± 0.042	2.002LysThr: 2.002 ± 0.049	2.831LysVal: 2.831 ± 0.056	0.506LysTrp: 0.506 ± 0.024	0.888LysTyr: 0.888 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	10.883LeuAla: 10.883 ± 0.127	0.829LeuCys: 0.829 ± 0.027	5.273LeuAsp: 5.273 ± 0.083	6.754LeuGlu: 6.754 ± 0.096	3.756LeuPhe: 3.756 ± 0.077	8.659LeuGly: 8.659 ± 0.108	2.307LeuHis: 2.307 ± 0.052	4.81LeuIle: 4.81 ± 0.075	3.37LeuLys: 3.37 ± 0.065	9.767LeuLeu: 9.767 ± 0.126	2.177LeuMet: 2.177 ± 0.054	2.444LeuAsn: 2.444 ± 0.052	5.158LeuPro: 5.158 ± 0.076	3.504LeuGln: 3.504 ± 0.065	7.735LeuArg: 7.735 ± 0.093	5.79LeuSer: 5.79 ± 0.089	5.19LeuThr: 5.19 ± 0.083	7.841LeuVal: 7.841 ± 0.097	1.554LeuTrp: 1.554 ± 0.043	2.762LeuTyr: 2.762 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	2.907MetAla: 2.907 ± 0.055	0.172MetCys: 0.172 ± 0.013	1.336MetAsp: 1.336 ± 0.033	1.822MetGlu: 1.822 ± 0.048	0.796MetPhe: 0.796 ± 0.03	2.056MetGly: 2.056 ± 0.049	0.445MetHis: 0.445 ± 0.024	1.385MetIle: 1.385 ± 0.042	1.224MetLys: 1.224 ± 0.035	1.871MetLeu: 1.871 ± 0.043	0.721MetMet: 0.721 ± 0.027	0.812MetAsn: 0.812 ± 0.029	1.156MetPro: 1.156 ± 0.038	0.683MetGln: 0.683 ± 0.027	1.745MetArg: 1.745 ± 0.043	1.396MetSer: 1.396 ± 0.043	1.362MetThr: 1.362 ± 0.038	1.979MetVal: 1.979 ± 0.043	0.298MetTrp: 0.298 ± 0.017	0.538MetTyr: 0.538 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.044AsnAla: 2.044 ± 0.052	0.232AsnCys: 0.232 ± 0.016	1.052AsnAsp: 1.052 ± 0.034	1.246AsnGlu: 1.246 ± 0.034	0.731AsnPhe: 0.731 ± 0.031	1.945AsnGly: 1.945 ± 0.057	0.595AsnHis: 0.595 ± 0.025	1.244AsnIle: 1.244 ± 0.04	0.721AsnLys: 0.721 ± 0.028	2.551AsnLeu: 2.551 ± 0.055	0.509AsnMet: 0.509 ± 0.024	0.571AsnAsn: 0.571 ± 0.026	1.906AsnPro: 1.906 ± 0.051	0.982AsnGln: 0.982 ± 0.036	2.214AsnArg: 2.214 ± 0.049	1.046AsnSer: 1.046 ± 0.041	1.092AsnThr: 1.092 ± 0.037	1.951AsnVal: 1.951 ± 0.052	0.399AsnTrp: 0.399 ± 0.02	0.619AsnTyr: 0.619 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	4.843ProAla: 4.843 ± 0.097	0.291ProCys: 0.291 ± 0.018	3.321ProAsp: 3.321 ± 0.061	4.472ProGlu: 4.472 ± 0.08	1.874ProPhe: 1.874 ± 0.048	6.026ProGly: 6.026 ± 0.097	1.042ProHis: 1.042 ± 0.034	2.169ProIle: 2.169 ± 0.054	1.769ProLys: 1.769 ± 0.043	4.572ProLeu: 4.572 ± 0.076	1.182ProMet: 1.182 ± 0.03	1.197ProAsn: 1.197 ± 0.041	2.562ProPro: 2.562 ± 0.064	1.536ProGln: 1.536 ± 0.04	3.078ProArg: 3.078 ± 0.058	2.769ProSer: 2.769 ± 0.056	2.302ProThr: 2.302 ± 0.056	4.896ProVal: 4.896 ± 0.071	0.933ProTrp: 0.933 ± 0.033	1.354ProTyr: 1.354 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.72GlnAla: 3.72 ± 0.085	0.237GlnCys: 0.237 ± 0.014	1.483GlnAsp: 1.483 ± 0.039	2.413GlnGlu: 2.413 ± 0.058	1.142GlnPhe: 1.142 ± 0.035	3.001GlnGly: 3.001 ± 0.062	0.643GlnHis: 0.643 ± 0.027	1.954GlnIle: 1.954 ± 0.047	1.398GlnLys: 1.398 ± 0.043	3.289GlnLeu: 3.289 ± 0.074	0.992GlnMet: 0.992 ± 0.033	0.893GlnAsn: 0.893 ± 0.028	1.594GlnPro: 1.594 ± 0.045	1.452GlnGln: 1.452 ± 0.055	2.535GlnArg: 2.535 ± 0.055	1.773GlnSer: 1.773 ± 0.047	1.809GlnThr: 1.809 ± 0.049	3.079GlnVal: 3.079 ± 0.071	0.698GlnTrp: 0.698 ± 0.027	0.948GlnTyr: 0.948 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	6.769ArgAla: 6.769 ± 0.105	0.682ArgCys: 0.682 ± 0.031	3.965ArgAsp: 3.965 ± 0.069	6.302ArgGlu: 6.302 ± 0.1	2.901ArgPhe: 2.901 ± 0.059	5.732ArgGly: 5.732 ± 0.096	1.757ArgHis: 1.757 ± 0.047	4.39ArgIle: 4.39 ± 0.079	2.738ArgLys: 2.738 ± 0.061	8.15ArgLeu: 8.15 ± 0.108	2.243ArgMet: 2.243 ± 0.049	1.766ArgAsn: 1.766 ± 0.047	3.969ArgPro: 3.969 ± 0.073	2.911ArgGln: 2.911 ± 0.066	7.616ArgArg: 7.616 ± 0.136	3.682ArgSer: 3.682 ± 0.059	3.437ArgThr: 3.437 ± 0.056	6.8ArgVal: 6.8 ± 0.105	1.506ArgTrp: 1.506 ± 0.043	2.123ArgTyr: 2.123 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	4.757SerAla: 4.757 ± 0.071	0.382SerCys: 0.382 ± 0.022	2.227SerAsp: 2.227 ± 0.053	2.793SerGlu: 2.793 ± 0.047	1.935SerPhe: 1.935 ± 0.046	5.254SerGly: 5.254 ± 0.078	1.064SerHis: 1.064 ± 0.03	2.318SerIle: 2.318 ± 0.058	1.446SerLys: 1.446 ± 0.044	5.25SerLeu: 5.25 ± 0.093	1.298SerMet: 1.298 ± 0.034	1.105SerAsn: 1.105 ± 0.04	2.992SerPro: 2.992 ± 0.065	1.563SerGln: 1.563 ± 0.049	3.944SerArg: 3.944 ± 0.064	2.723SerSer: 2.723 ± 0.061	2.462SerThr: 2.462 ± 0.049	4.077SerVal: 4.077 ± 0.06	0.881SerTrp: 0.881 ± 0.028	1.251SerTyr: 1.251 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	5.182ThrAla: 5.182 ± 0.078	0.425ThrCys: 0.425 ± 0.02	2.311ThrAsp: 2.311 ± 0.049	2.692ThrGlu: 2.692 ± 0.06	1.933ThrPhe: 1.933 ± 0.048	4.961ThrGly: 4.961 ± 0.072	0.959ThrHis: 0.959 ± 0.031	2.34ThrIle: 2.34 ± 0.055	1.473ThrLys: 1.473 ± 0.041	4.953ThrLeu: 4.953 ± 0.07	1.155ThrMet: 1.155 ± 0.038	1.083ThrAsn: 1.083 ± 0.038	3.015ThrPro: 3.015 ± 0.061	1.259ThrGln: 1.259 ± 0.036	3.025ThrArg: 3.025 ± 0.054	2.355ThrSer: 2.355 ± 0.05	2.361ThrThr: 2.361 ± 0.051	4.797ThrVal: 4.797 ± 0.084	0.819ThrTrp: 0.819 ± 0.028	1.364ThrTyr: 1.364 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	8.547ValAla: 8.547 ± 0.118	0.761ValCys: 0.761 ± 0.029	4.841ValAsp: 4.841 ± 0.081	6.013ValGlu: 6.013 ± 0.097	3.086ValPhe: 3.086 ± 0.068	6.515ValGly: 6.515 ± 0.1	1.935ValHis: 1.935 ± 0.047	4.612ValIle: 4.612 ± 0.076	2.933ValLys: 2.933 ± 0.052	8.666ValLeu: 8.666 ± 0.104	2.023ValMet: 2.023 ± 0.049	2.291ValAsn: 2.291 ± 0.05	4.366ValPro: 4.366 ± 0.068	3.097ValGln: 3.097 ± 0.059	6.48ValArg: 6.48 ± 0.085	4.573ValSer: 4.573 ± 0.069	4.319ValThr: 4.319 ± 0.074	8.069ValVal: 8.069 ± 0.106	1.159ValTrp: 1.159 ± 0.039	2.328ValTyr: 2.328 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	1.394TrpAla: 1.394 ± 0.044	0.131TrpCys: 0.131 ± 0.012	0.757TrpAsp: 0.757 ± 0.029	1.074TrpGlu: 1.074 ± 0.036	0.651TrpPhe: 0.651 ± 0.028	1.055TrpGly: 1.055 ± 0.036	0.319TrpHis: 0.319 ± 0.016	1.02TrpIle: 1.02 ± 0.035	0.672TrpLys: 0.672 ± 0.029	1.914TrpLeu: 1.914 ± 0.047	0.537TrpMet: 0.537 ± 0.022	0.558TrpAsn: 0.558 ± 0.026	0.727TrpPro: 0.727 ± 0.029	0.521TrpGln: 0.521 ± 0.023	1.271TrpArg: 1.271 ± 0.043	0.843TrpSer: 0.843 ± 0.03	0.9TrpThr: 0.9 ± 0.029	1.353TrpVal: 1.353 ± 0.036	0.352TrpTrp: 0.352 ± 0.023	0.393TrpTyr: 0.393 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.38TyrAla: 2.38 ± 0.053	0.314TyrCys: 0.314 ± 0.019	1.481TyrAsp: 1.481 ± 0.041	1.661TyrGlu: 1.661 ± 0.044	1.021TyrPhe: 1.021 ± 0.034	2.474TyrGly: 2.474 ± 0.049	0.702TyrHis: 0.702 ± 0.026	1.179TyrIle: 1.179 ± 0.036	0.699TyrLys: 0.699 ± 0.024	2.779TyrLeu: 2.779 ± 0.062	0.523TyrMet: 0.523 ± 0.025	0.655TyrAsn: 0.655 ± 0.025	1.486TyrPro: 1.486 ± 0.045	0.959TyrGln: 0.959 ± 0.029	2.499TyrArg: 2.499 ± 0.055	1.195TyrSer: 1.195 ± 0.039	1.431TyrThr: 1.431 ± 0.039	2.105TyrVal: 2.105 ± 0.049	0.395TyrTrp: 0.395 ± 0.023	0.804TyrTyr: 0.804 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3135 proteins (950009 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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