Amino acid dipepetide frequency for Beihai sobemo-like virus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.177AlaAla: 4.177 ± 0.828
0.835AlaCys: 0.835 ± 0.461
8.354AlaAsp: 8.354 ± 1.3
0.835AlaGlu: 0.835 ± 0.461
3.342AlaPhe: 3.342 ± 0.367
5.848AlaGly: 5.848 ± 1.751
1.671AlaHis: 1.671 ± 0.556
5.013AlaIle: 5.013 ± 1.667
1.671AlaLys: 1.671 ± 0.922
9.19AlaLeu: 9.19 ± 2.117
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
2.506AlaPro: 2.506 ± 0.094
1.671AlaGln: 1.671 ± 0.922
3.342AlaArg: 3.342 ± 1.111
5.013AlaSer: 5.013 ± 0.189
2.506AlaThr: 2.506 ± 1.384
5.013AlaVal: 5.013 ± 1.289
2.506AlaTrp: 2.506 ± 1.573
3.342AlaTyr: 3.342 ± 1.111
0.0AlaXaa: 0.0 ± 0.0
Cys
0.835CysAla: 0.835 ± 0.461
0.0CysCys: 0.0 ± 0.0
0.835CysAsp: 0.835 ± 0.461
0.0CysGlu: 0.0 ± 0.0
0.835CysPhe: 0.835 ± 0.461
0.835CysGly: 0.835 ± 1.017
0.0CysHis: 0.0 ± 0.0
0.835CysIle: 0.835 ± 1.017
0.0CysLys: 0.0 ± 0.0
0.835CysLeu: 0.835 ± 1.017
0.0CysMet: 0.0 ± 0.0
0.835CysAsn: 0.835 ± 0.461
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.835CysArg: 0.835 ± 0.461
0.835CysSer: 0.835 ± 0.461
0.0CysThr: 0.0 ± 0.0
1.671CysVal: 1.671 ± 0.922
0.0CysTrp: 0.0 ± 0.0
0.835CysTyr: 0.835 ± 1.017
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
4.177AspAsp: 4.177 ± 3.607
7.519AspGlu: 7.519 ± 1.195
4.177AspPhe: 4.177 ± 0.65
3.342AspGly: 3.342 ± 0.367
1.671AspHis: 1.671 ± 0.922
2.506AspIle: 2.506 ± 0.094
2.506AspLys: 2.506 ± 1.573
5.848AspLeu: 5.848 ± 0.272
1.671AspMet: 1.671 ± 0.556
0.0AspAsn: 0.0 ± 0.0
5.013AspPro: 5.013 ± 1.667
0.835AspGln: 0.835 ± 1.017
3.342AspArg: 3.342 ± 1.111
5.848AspSer: 5.848 ± 0.272
5.013AspThr: 5.013 ± 1.289
3.342AspVal: 3.342 ± 0.367
1.671AspTrp: 1.671 ± 2.034
3.342AspTyr: 3.342 ± 1.111
0.0AspXaa: 0.0 ± 0.0
Glu
6.683GluAla: 6.683 ± 0.734
0.835GluCys: 0.835 ± 0.461
7.519GluAsp: 7.519 ± 4.151
5.848GluGlu: 5.848 ± 0.272
2.506GluPhe: 2.506 ± 0.094
1.671GluGly: 1.671 ± 0.922
0.0GluHis: 0.0 ± 0.0
5.013GluIle: 5.013 ± 0.189
2.506GluLys: 2.506 ± 1.384
4.177GluLeu: 4.177 ± 3.607
0.0GluMet: 0.0 ± 0.0
1.671GluAsn: 1.671 ± 0.922
1.671GluPro: 1.671 ± 2.034
1.671GluGln: 1.671 ± 0.922
5.013GluArg: 5.013 ± 0.189
4.177GluSer: 4.177 ± 2.306
4.177GluThr: 4.177 ± 2.128
5.013GluVal: 5.013 ± 1.289
0.835GluTrp: 0.835 ± 0.461
2.506GluTyr: 2.506 ± 0.094
0.0GluXaa: 0.0 ± 0.0
Phe
1.671PheAla: 1.671 ± 2.034
0.835PheCys: 0.835 ± 1.017
5.013PheAsp: 5.013 ± 4.624
4.177PheGlu: 4.177 ± 0.828
4.177PhePhe: 4.177 ± 0.828
3.342PheGly: 3.342 ± 0.367
0.835PheHis: 0.835 ± 0.461
2.506PheIle: 2.506 ± 0.094
1.671PheLys: 1.671 ± 0.556
4.177PheLeu: 4.177 ± 2.306
1.671PheMet: 1.671 ± 2.034
2.506PheAsn: 2.506 ± 1.573
0.835PhePro: 0.835 ± 0.461
0.835PheGln: 0.835 ± 1.017
1.671PheArg: 1.671 ± 0.556
1.671PheSer: 1.671 ± 0.556
1.671PheThr: 1.671 ± 0.556
1.671PheVal: 1.671 ± 0.556
0.835PheTrp: 0.835 ± 0.461
2.506PheTyr: 2.506 ± 0.094
0.0PheXaa: 0.0 ± 0.0
Gly
2.506GlyAla: 2.506 ± 1.384
0.835GlyCys: 0.835 ± 1.017
4.177GlyAsp: 4.177 ± 0.65
1.671GlyGlu: 1.671 ± 0.556
2.506GlyPhe: 2.506 ± 1.573
3.342GlyGly: 3.342 ± 1.845
0.0GlyHis: 0.0 ± 0.0
4.177GlyIle: 4.177 ± 0.65
4.177GlyLys: 4.177 ± 2.306
10.025GlyLeu: 10.025 ± 0.378
0.835GlyMet: 0.835 ± 0.461
0.835GlyAsn: 0.835 ± 0.461
2.506GlyPro: 2.506 ± 0.094
1.671GlyGln: 1.671 ± 0.922
3.342GlyArg: 3.342 ± 0.367
5.848GlySer: 5.848 ± 1.206
3.342GlyThr: 3.342 ± 1.845
4.177GlyVal: 4.177 ± 2.306
3.342GlyTrp: 3.342 ± 1.111
3.342GlyTyr: 3.342 ± 1.111
0.0GlyXaa: 0.0 ± 0.0
His
2.506HisAla: 2.506 ± 0.094
0.835HisCys: 0.835 ± 0.461
1.671HisAsp: 1.671 ± 0.922
0.0HisGlu: 0.0 ± 0.0
1.671HisPhe: 1.671 ± 0.922
0.835HisGly: 0.835 ± 0.461
1.671HisHis: 1.671 ± 2.034
1.671HisIle: 1.671 ± 2.034
1.671HisLys: 1.671 ± 0.556
1.671HisLeu: 1.671 ± 0.556
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.835HisArg: 0.835 ± 0.461
0.835HisSer: 0.835 ± 1.017
0.835HisThr: 0.835 ± 0.461
1.671HisVal: 1.671 ± 0.922
0.835HisTrp: 0.835 ± 0.461
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.013IleAla: 5.013 ± 2.767
1.671IleCys: 1.671 ± 2.034
0.835IleAsp: 0.835 ± 0.461
0.835IleGlu: 0.835 ± 1.017
2.506IlePhe: 2.506 ± 0.094
4.177IleGly: 4.177 ± 2.128
0.835IleHis: 0.835 ± 1.017
0.835IleIle: 0.835 ± 0.461
1.671IleLys: 1.671 ± 0.556
8.354IleLeu: 8.354 ± 0.178
3.342IleMet: 3.342 ± 1.111
2.506IleAsn: 2.506 ± 1.573
2.506IlePro: 2.506 ± 0.094
2.506IleGln: 2.506 ± 1.573
4.177IleArg: 4.177 ± 0.65
2.506IleSer: 2.506 ± 1.573
2.506IleThr: 2.506 ± 1.384
2.506IleVal: 2.506 ± 0.094
0.835IleTrp: 0.835 ± 0.461
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.177LysAla: 4.177 ± 0.828
0.0LysCys: 0.0 ± 0.0
1.671LysAsp: 1.671 ± 0.922
3.342LysGlu: 3.342 ± 1.111
0.0LysPhe: 0.0 ± 0.0
1.671LysGly: 1.671 ± 0.922
0.0LysHis: 0.0 ± 0.0
3.342LysIle: 3.342 ± 1.845
8.354LysLys: 8.354 ± 3.134
5.013LysLeu: 5.013 ± 2.767
0.835LysMet: 0.835 ± 0.461
4.177LysAsn: 4.177 ± 0.828
4.177LysPro: 4.177 ± 2.306
2.506LysGln: 2.506 ± 3.051
2.506LysArg: 2.506 ± 1.384
4.177LysSer: 4.177 ± 0.828
6.683LysThr: 6.683 ± 0.734
1.671LysVal: 1.671 ± 0.556
0.0LysTrp: 0.0 ± 0.0
1.671LysTyr: 1.671 ± 0.556
0.0LysXaa: 0.0 ± 0.0
Leu
6.683LeuAla: 6.683 ± 2.223
0.0LeuCys: 0.0 ± 0.0
4.177LeuAsp: 4.177 ± 0.65
7.519LeuGlu: 7.519 ± 0.283
6.683LeuPhe: 6.683 ± 3.701
6.683LeuGly: 6.683 ± 2.212
3.342LeuHis: 3.342 ± 0.367
2.506LeuIle: 2.506 ± 1.573
5.013LeuLys: 5.013 ± 1.667
6.683LeuLeu: 6.683 ± 3.69
2.506LeuMet: 2.506 ± 0.497
3.342LeuAsn: 3.342 ± 1.845
5.013LeuPro: 5.013 ± 1.667
5.013LeuGln: 5.013 ± 2.767
8.354LeuArg: 8.354 ± 1.656
8.354LeuSer: 8.354 ± 1.656
6.683LeuThr: 6.683 ± 0.745
5.848LeuVal: 5.848 ± 1.206
1.671LeuTrp: 1.671 ± 0.922
3.342LeuTyr: 3.342 ± 0.367
0.0LeuXaa: 0.0 ± 0.0
Met
1.671MetAla: 1.671 ± 0.556
0.0MetCys: 0.0 ± 0.0
2.506MetAsp: 2.506 ± 0.094
0.835MetGlu: 0.835 ± 0.461
0.0MetPhe: 0.0 ± 0.0
0.835MetGly: 0.835 ± 1.017
0.835MetHis: 0.835 ± 0.461
0.835MetIle: 0.835 ± 0.461
0.0MetLys: 0.0 ± 0.0
3.342MetLeu: 3.342 ± 1.111
0.0MetMet: 0.0 ± 0.0
0.835MetAsn: 0.835 ± 1.017
2.506MetPro: 2.506 ± 1.573
1.671MetGln: 1.671 ± 2.034
1.671MetArg: 1.671 ± 2.034
0.0MetSer: 0.0 ± 0.0
1.671MetThr: 1.671 ± 0.556
1.671MetVal: 1.671 ± 0.922
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.835AsnAla: 0.835 ± 1.017
0.835AsnCys: 0.835 ± 0.461
0.835AsnAsp: 0.835 ± 0.461
2.506AsnGlu: 2.506 ± 0.094
1.671AsnPhe: 1.671 ± 0.556
4.177AsnGly: 4.177 ± 0.65
0.0AsnHis: 0.0 ± 0.0
1.671AsnIle: 1.671 ± 0.556
3.342AsnLys: 3.342 ± 0.367
5.013AsnLeu: 5.013 ± 2.767
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.671AsnPro: 1.671 ± 0.922
3.342AsnGln: 3.342 ± 0.367
3.342AsnArg: 3.342 ± 1.111
2.506AsnSer: 2.506 ± 0.094
2.506AsnThr: 2.506 ± 1.384
0.835AsnVal: 0.835 ± 0.461
0.0AsnTrp: 0.0 ± 0.0
0.835AsnTyr: 0.835 ± 0.461
0.0AsnXaa: 0.0 ± 0.0
Pro
2.506ProAla: 2.506 ± 1.384
0.0ProCys: 0.0 ± 0.0
2.506ProAsp: 2.506 ± 1.573
4.177ProGlu: 4.177 ± 0.828
1.671ProPhe: 1.671 ± 0.556
4.177ProGly: 4.177 ± 3.607
0.835ProHis: 0.835 ± 0.461
1.671ProIle: 1.671 ± 0.556
3.342ProLys: 3.342 ± 1.845
2.506ProLeu: 2.506 ± 0.094
0.835ProMet: 0.835 ± 1.017
0.835ProAsn: 0.835 ± 0.461
1.671ProPro: 1.671 ± 0.922
6.683ProGln: 6.683 ± 2.223
1.671ProArg: 1.671 ± 0.556
6.683ProSer: 6.683 ± 0.734
2.506ProThr: 2.506 ± 1.384
3.342ProVal: 3.342 ± 2.59
3.342ProTrp: 3.342 ± 1.111
0.835ProTyr: 0.835 ± 0.461
0.0ProXaa: 0.0 ± 0.0
Gln
1.671GlnAla: 1.671 ± 0.556
0.0GlnCys: 0.0 ± 0.0
2.506GlnAsp: 2.506 ± 0.094
5.848GlnGlu: 5.848 ± 0.272
0.835GlnPhe: 0.835 ± 1.017
2.506GlnGly: 2.506 ± 1.384
0.0GlnHis: 0.0 ± 0.0
2.506GlnIle: 2.506 ± 0.094
3.342GlnLys: 3.342 ± 0.367
5.013GlnLeu: 5.013 ± 0.189
0.835GlnMet: 0.835 ± 0.461
2.506GlnAsn: 2.506 ± 0.094
4.177GlnPro: 4.177 ± 0.65
4.177GlnGln: 4.177 ± 0.65
3.342GlnArg: 3.342 ± 2.59
2.506GlnSer: 2.506 ± 1.384
0.835GlnThr: 0.835 ± 0.461
0.835GlnVal: 0.835 ± 0.461
0.835GlnTrp: 0.835 ± 1.017
1.671GlnTyr: 1.671 ± 0.556
0.0GlnXaa: 0.0 ± 0.0
Arg
6.683ArgAla: 6.683 ± 2.212
0.0ArgCys: 0.0 ± 0.0
1.671ArgAsp: 1.671 ± 2.034
5.013ArgGlu: 5.013 ± 0.189
4.177ArgPhe: 4.177 ± 0.828
0.0ArgGly: 0.0 ± 0.0
1.671ArgHis: 1.671 ± 0.556
2.506ArgIle: 2.506 ± 0.094
2.506ArgLys: 2.506 ± 0.094
7.519ArgLeu: 7.519 ± 3.24
4.177ArgMet: 4.177 ± 3.607
0.835ArgAsn: 0.835 ± 0.461
5.848ArgPro: 5.848 ± 0.272
3.342ArgGln: 3.342 ± 0.367
6.683ArgArg: 6.683 ± 0.734
1.671ArgSer: 1.671 ± 0.922
2.506ArgThr: 2.506 ± 1.384
3.342ArgVal: 3.342 ± 0.367
0.835ArgTrp: 0.835 ± 1.017
3.342ArgTyr: 3.342 ± 1.111
0.0ArgXaa: 0.0 ± 0.0
Ser
4.177SerAla: 4.177 ± 2.128
0.835SerCys: 0.835 ± 0.461
2.506SerAsp: 2.506 ± 1.384
2.506SerGlu: 2.506 ± 1.384
0.835SerPhe: 0.835 ± 1.017
4.177SerGly: 4.177 ± 0.828
0.835SerHis: 0.835 ± 0.461
2.506SerIle: 2.506 ± 0.094
5.848SerLys: 5.848 ± 3.229
7.519SerLeu: 7.519 ± 1.195
0.0SerMet: 0.0 ± 0.0
5.848SerAsn: 5.848 ± 1.751
4.177SerPro: 4.177 ± 2.128
5.848SerGln: 5.848 ± 1.751
3.342SerArg: 3.342 ± 0.367
9.19SerSer: 9.19 ± 0.639
4.177SerThr: 4.177 ± 0.828
10.025SerVal: 10.025 ± 1.1
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.177ThrAla: 4.177 ± 0.828
1.671ThrCys: 1.671 ± 0.922
4.177ThrAsp: 4.177 ± 0.65
2.506ThrGlu: 2.506 ± 1.384
1.671ThrPhe: 1.671 ± 2.034
5.013ThrGly: 5.013 ± 1.289
2.506ThrHis: 2.506 ± 1.384
3.342ThrIle: 3.342 ± 2.59
3.342ThrLys: 3.342 ± 1.845
2.506ThrLeu: 2.506 ± 0.094
1.671ThrMet: 1.671 ± 0.426
1.671ThrAsn: 1.671 ± 0.556
1.671ThrPro: 1.671 ± 0.922
0.0ThrGln: 0.0 ± 0.0
2.506ThrArg: 2.506 ± 1.384
5.013ThrSer: 5.013 ± 2.767
2.506ThrThr: 2.506 ± 1.384
6.683ThrVal: 6.683 ± 2.212
0.835ThrTrp: 0.835 ± 0.461
0.835ThrTyr: 0.835 ± 0.461
0.0ThrXaa: 0.0 ± 0.0
Val
5.848ValAla: 5.848 ± 1.751
0.835ValCys: 0.835 ± 0.461
2.506ValAsp: 2.506 ± 1.384
6.683ValGlu: 6.683 ± 0.734
2.506ValPhe: 2.506 ± 1.573
5.013ValGly: 5.013 ± 0.189
0.835ValHis: 0.835 ± 0.461
3.342ValIle: 3.342 ± 1.845
3.342ValLys: 3.342 ± 0.367
4.177ValLeu: 4.177 ± 2.128
0.835ValMet: 0.835 ± 1.017
3.342ValAsn: 3.342 ± 1.845
4.177ValPro: 4.177 ± 0.65
2.506ValGln: 2.506 ± 0.094
5.013ValArg: 5.013 ± 0.189
5.013ValSer: 5.013 ± 1.289
3.342ValThr: 3.342 ± 1.845
4.177ValVal: 4.177 ± 0.828
0.835ValTrp: 0.835 ± 0.461
2.506ValTyr: 2.506 ± 0.094
0.0ValXaa: 0.0 ± 0.0
Trp
0.835TrpAla: 0.835 ± 0.461
0.0TrpCys: 0.0 ± 0.0
1.671TrpAsp: 1.671 ± 2.034
0.835TrpGlu: 0.835 ± 0.461
0.835TrpPhe: 0.835 ± 1.017
2.506TrpGly: 2.506 ± 0.094
0.835TrpHis: 0.835 ± 1.017
1.671TrpIle: 1.671 ± 0.556
0.835TrpLys: 0.835 ± 0.461
3.342TrpLeu: 3.342 ± 1.111
0.0TrpMet: 0.0 ± 0.0
0.835TrpAsn: 0.835 ± 0.461
1.671TrpPro: 1.671 ± 0.556
0.0TrpGln: 0.0 ± 0.0
1.671TrpArg: 1.671 ± 0.556
0.835TrpSer: 0.835 ± 0.461
1.671TrpThr: 1.671 ± 0.556
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.177TyrAla: 4.177 ± 2.128
0.0TyrCys: 0.0 ± 0.0
2.506TyrAsp: 2.506 ± 1.573
0.835TyrGlu: 0.835 ± 0.461
1.671TyrPhe: 1.671 ± 0.922
2.506TyrGly: 2.506 ± 0.094
0.835TyrHis: 0.835 ± 1.017
1.671TyrIle: 1.671 ± 0.556
0.835TyrLys: 0.835 ± 0.461
2.506TyrLeu: 2.506 ± 0.094
0.835TyrMet: 0.835 ± 0.461
3.342TyrAsn: 3.342 ± 1.111
0.0TyrPro: 0.0 ± 0.0
1.671TyrGln: 1.671 ± 0.922
1.671TyrArg: 1.671 ± 0.556
1.671TyrSer: 1.671 ± 0.922
0.0TyrThr: 0.0 ± 0.0
3.342TyrVal: 3.342 ± 1.111
0.835TyrTrp: 0.835 ± 1.017
0.835TyrTyr: 0.835 ± 0.461
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1198 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski