Amino acid dipepetide frequency for Puerto Almendras virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.852AlaAla: 0.852 ± 0.537
0.0AlaCys: 0.0 ± 0.0
1.42AlaAsp: 1.42 ± 0.549
1.704AlaGlu: 1.704 ± 0.476
0.852AlaPhe: 0.852 ± 0.358
0.568AlaGly: 0.568 ± 0.331
1.136AlaHis: 1.136 ± 0.415
1.42AlaIle: 1.42 ± 1.263
1.988AlaLys: 1.988 ± 0.664
2.272AlaLeu: 2.272 ± 0.651
0.568AlaMet: 0.568 ± 0.902
1.988AlaAsn: 1.988 ± 0.959
0.852AlaPro: 0.852 ± 0.622
0.0AlaGln: 0.0 ± 0.0
1.42AlaArg: 1.42 ± 0.726
3.124AlaSer: 3.124 ± 0.895
1.988AlaThr: 1.988 ± 1.179
2.272AlaVal: 2.272 ± 0.781
0.0AlaTrp: 0.0 ± 0.0
1.704AlaTyr: 1.704 ± 0.604
0.0AlaXaa: 0.0 ± 0.0
Cys
0.852CysAla: 0.852 ± 0.81
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.284CysGlu: 0.284 ± 0.376
0.568CysPhe: 0.568 ± 0.331
0.568CysGly: 0.568 ± 0.331
0.0CysHis: 0.0 ± 0.0
1.136CysIle: 1.136 ± 0.426
1.136CysLys: 1.136 ± 1.184
1.988CysLeu: 1.988 ± 0.799
0.568CysMet: 0.568 ± 0.92
1.42CysAsn: 1.42 ± 0.649
0.852CysPro: 0.852 ± 0.851
0.852CysGln: 0.852 ± 0.423
0.284CysArg: 0.284 ± 0.165
0.568CysSer: 0.568 ± 0.328
1.988CysThr: 1.988 ± 1.561
0.284CysVal: 0.284 ± 0.165
0.852CysTrp: 0.852 ± 0.496
1.42CysTyr: 1.42 ± 0.827
0.0CysXaa: 0.0 ± 0.0
Asp
0.852AspAla: 0.852 ± 0.443
1.704AspCys: 1.704 ± 1.135
3.124AspAsp: 3.124 ± 0.515
3.976AspGlu: 3.976 ± 1.169
1.988AspPhe: 1.988 ± 1.158
2.272AspGly: 2.272 ± 0.842
0.852AspHis: 0.852 ± 0.496
4.828AspIle: 4.828 ± 1.745
4.544AspLys: 4.544 ± 1.118
5.964AspLeu: 5.964 ± 2.057
1.704AspMet: 1.704 ± 0.453
5.396AspAsn: 5.396 ± 0.916
2.84AspPro: 2.84 ± 1.04
1.704AspGln: 1.704 ± 0.453
3.124AspArg: 3.124 ± 0.882
5.964AspSer: 5.964 ± 2.287
3.124AspThr: 3.124 ± 2.082
1.42AspVal: 1.42 ± 0.647
0.852AspTrp: 0.852 ± 0.443
3.976AspTyr: 3.976 ± 0.948
0.0AspXaa: 0.0 ± 0.0
Glu
0.852GluAla: 0.852 ± 0.496
1.136GluCys: 1.136 ± 0.611
3.976GluAsp: 3.976 ± 0.767
5.112GluGlu: 5.112 ± 2.308
1.988GluPhe: 1.988 ± 0.535
1.704GluGly: 1.704 ± 0.563
1.42GluHis: 1.42 ± 0.788
7.384GluIle: 7.384 ± 1.393
5.396GluLys: 5.396 ± 1.326
5.68GluLeu: 5.68 ± 0.754
1.988GluMet: 1.988 ± 0.675
3.692GluAsn: 3.692 ± 1.743
2.272GluPro: 2.272 ± 1.436
0.852GluGln: 0.852 ± 0.496
1.704GluArg: 1.704 ± 0.625
4.26GluSer: 4.26 ± 1.205
2.556GluThr: 2.556 ± 0.83
2.84GluVal: 2.84 ± 0.917
0.568GluTrp: 0.568 ± 0.328
4.828GluTyr: 4.828 ± 0.806
0.0GluXaa: 0.0 ± 0.0
Phe
1.988PheAla: 1.988 ± 0.536
1.136PheCys: 1.136 ± 0.452
2.84PheAsp: 2.84 ± 1.094
3.408PheGlu: 3.408 ± 0.82
1.704PhePhe: 1.704 ± 0.571
2.556PheGly: 2.556 ± 0.833
0.568PheHis: 0.568 ± 0.331
3.124PheIle: 3.124 ± 0.75
3.124PheLys: 3.124 ± 1.752
2.272PheLeu: 2.272 ± 0.444
0.568PheMet: 0.568 ± 0.328
4.828PheAsn: 4.828 ± 1.185
1.704PhePro: 1.704 ± 0.794
1.136PheGln: 1.136 ± 0.358
1.988PheArg: 1.988 ± 0.796
3.408PheSer: 3.408 ± 1.245
2.556PheThr: 2.556 ± 0.673
1.704PheVal: 1.704 ± 0.611
0.284PheTrp: 0.284 ± 0.165
1.988PheTyr: 1.988 ± 0.909
0.0PheXaa: 0.0 ± 0.0
Gly
1.704GlyAla: 1.704 ± 0.647
0.0GlyCys: 0.0 ± 0.0
3.124GlyAsp: 3.124 ± 0.967
2.272GlyGlu: 2.272 ± 0.644
1.988GlyPhe: 1.988 ± 0.872
2.272GlyGly: 2.272 ± 0.947
1.136GlyHis: 1.136 ± 0.452
4.26GlyIle: 4.26 ± 0.944
2.556GlyLys: 2.556 ± 0.935
5.964GlyLeu: 5.964 ± 2.312
1.704GlyMet: 1.704 ± 0.652
1.988GlyAsn: 1.988 ± 0.551
0.284GlyPro: 0.284 ± 0.165
1.42GlyGln: 1.42 ± 0.549
1.704GlyArg: 1.704 ± 0.715
3.692GlySer: 3.692 ± 0.432
2.84GlyThr: 2.84 ± 0.743
1.988GlyVal: 1.988 ± 0.757
0.284GlyTrp: 0.284 ± 0.165
2.556GlyTyr: 2.556 ± 0.426
0.0GlyXaa: 0.0 ± 0.0
His
0.852HisAla: 0.852 ± 0.357
0.852HisCys: 0.852 ± 0.358
1.42HisAsp: 1.42 ± 1.007
0.568HisGlu: 0.568 ± 0.328
1.136HisPhe: 1.136 ± 0.738
0.852HisGly: 0.852 ± 0.357
0.852HisHis: 0.852 ± 0.423
1.988HisIle: 1.988 ± 0.55
1.42HisLys: 1.42 ± 0.899
2.272HisLeu: 2.272 ± 0.687
0.284HisMet: 0.284 ± 0.165
1.136HisAsn: 1.136 ± 0.353
1.136HisPro: 1.136 ± 0.358
1.136HisGln: 1.136 ± 0.452
0.852HisArg: 0.852 ± 0.562
0.568HisSer: 0.568 ± 0.326
1.136HisThr: 1.136 ± 0.452
1.42HisVal: 1.42 ± 0.696
0.0HisTrp: 0.0 ± 0.0
1.42HisTyr: 1.42 ± 0.578
0.0HisXaa: 0.0 ± 0.0
Ile
1.42IleAla: 1.42 ± 0.636
2.272IleCys: 2.272 ± 1.361
7.384IleAsp: 7.384 ± 1.506
4.26IleGlu: 4.26 ± 2.204
3.976IlePhe: 3.976 ± 0.609
5.112IleGly: 5.112 ± 1.123
0.568IleHis: 0.568 ± 0.568
11.076IleIle: 11.076 ± 2.324
8.804IleLys: 8.804 ± 0.985
9.088IleLeu: 9.088 ± 2.11
2.84IleMet: 2.84 ± 1.405
7.952IleAsn: 7.952 ± 1.211
4.544IlePro: 4.544 ± 1.148
1.42IleGln: 1.42 ± 0.442
5.964IleArg: 5.964 ± 1.172
6.816IleSer: 6.816 ± 2.509
5.112IleThr: 5.112 ± 0.75
3.124IleVal: 3.124 ± 1.612
0.284IleTrp: 0.284 ± 0.451
6.816IleTyr: 6.816 ± 1.355
0.0IleXaa: 0.0 ± 0.0
Lys
2.556LysAla: 2.556 ± 0.899
1.704LysCys: 1.704 ± 0.671
4.828LysAsp: 4.828 ± 0.604
6.248LysGlu: 6.248 ± 1.481
4.544LysPhe: 4.544 ± 1.151
3.124LysGly: 3.124 ± 1.197
1.42LysHis: 1.42 ± 0.827
7.668LysIle: 7.668 ± 2.183
4.828LysLys: 4.828 ± 0.936
8.804LysLeu: 8.804 ± 2.204
2.556LysMet: 2.556 ± 0.656
4.828LysAsn: 4.828 ± 0.966
1.136LysPro: 1.136 ± 0.641
1.136LysGln: 1.136 ± 0.353
3.408LysArg: 3.408 ± 0.52
3.976LysSer: 3.976 ± 0.82
5.396LysThr: 5.396 ± 0.91
3.408LysVal: 3.408 ± 0.87
1.988LysTrp: 1.988 ± 0.773
5.964LysTyr: 5.964 ± 0.786
0.0LysXaa: 0.0 ± 0.0
Leu
1.704LeuAla: 1.704 ± 1.115
0.568LeuCys: 0.568 ± 0.607
4.26LeuAsp: 4.26 ± 0.64
6.248LeuGlu: 6.248 ± 1.084
4.26LeuPhe: 4.26 ± 1.853
5.396LeuGly: 5.396 ± 1.763
1.136LeuHis: 1.136 ± 1.037
9.372LeuIle: 9.372 ± 2.595
6.532LeuLys: 6.532 ± 0.873
8.52LeuLeu: 8.52 ± 1.318
2.84LeuMet: 2.84 ± 0.521
11.928LeuAsn: 11.928 ± 2.4
2.272LeuPro: 2.272 ± 0.634
2.84LeuGln: 2.84 ± 0.786
5.112LeuArg: 5.112 ± 0.659
5.68LeuSer: 5.68 ± 0.424
5.964LeuThr: 5.964 ± 1.225
3.692LeuVal: 3.692 ± 1.372
0.568LeuTrp: 0.568 ± 0.607
3.692LeuTyr: 3.692 ± 1.503
0.0LeuXaa: 0.0 ± 0.0
Met
0.568MetAla: 0.568 ± 0.331
0.284MetCys: 0.284 ± 0.165
1.136MetAsp: 1.136 ± 0.452
0.852MetGlu: 0.852 ± 0.81
1.136MetPhe: 1.136 ± 1.437
1.704MetGly: 1.704 ± 0.436
0.284MetHis: 0.284 ± 0.606
2.84MetIle: 2.84 ± 0.841
2.272MetLys: 2.272 ± 1.145
1.136MetLeu: 1.136 ± 0.415
1.704MetMet: 1.704 ± 0.787
1.988MetAsn: 1.988 ± 0.62
1.136MetPro: 1.136 ± 0.656
0.852MetGln: 0.852 ± 0.496
0.0MetArg: 0.0 ± 0.0
3.408MetSer: 3.408 ± 1.525
0.852MetThr: 0.852 ± 1.158
1.42MetVal: 1.42 ± 0.975
0.568MetTrp: 0.568 ± 0.331
1.42MetTyr: 1.42 ± 1.123
0.0MetXaa: 0.0 ± 0.0
Asn
1.704AsnAla: 1.704 ± 0.453
0.568AsnCys: 0.568 ± 0.326
5.112AsnAsp: 5.112 ± 1.976
3.976AsnGlu: 3.976 ± 1.091
3.692AsnPhe: 3.692 ± 0.86
3.692AsnGly: 3.692 ± 1.109
3.408AsnHis: 3.408 ± 1.067
7.952AsnIle: 7.952 ± 1.548
7.1AsnLys: 7.1 ± 1.168
7.952AsnLeu: 7.952 ± 1.136
1.704AsnMet: 1.704 ± 0.782
6.816AsnAsn: 6.816 ± 1.759
2.84AsnPro: 2.84 ± 1.26
1.704AsnGln: 1.704 ± 0.69
3.976AsnArg: 3.976 ± 1.54
5.68AsnSer: 5.68 ± 0.6
4.828AsnThr: 4.828 ± 0.61
4.828AsnVal: 4.828 ± 1.063
0.568AsnTrp: 0.568 ± 0.331
2.84AsnTyr: 2.84 ± 0.366
0.0AsnXaa: 0.0 ± 0.0
Pro
0.284ProAla: 0.284 ± 0.376
0.284ProCys: 0.284 ± 0.165
2.556ProAsp: 2.556 ± 1.063
2.272ProGlu: 2.272 ± 0.671
1.42ProPhe: 1.42 ± 0.837
0.568ProGly: 0.568 ± 0.331
1.136ProHis: 1.136 ± 0.452
5.112ProIle: 5.112 ± 0.976
1.42ProLys: 1.42 ± 0.363
1.136ProLeu: 1.136 ± 0.662
0.852ProMet: 0.852 ± 0.651
1.988ProAsn: 1.988 ± 0.718
1.136ProPro: 1.136 ± 0.662
0.852ProGln: 0.852 ± 0.357
1.42ProArg: 1.42 ± 0.546
2.84ProSer: 2.84 ± 1.433
1.988ProThr: 1.988 ± 0.563
2.272ProVal: 2.272 ± 1.085
0.284ProTrp: 0.284 ± 0.165
1.988ProTyr: 1.988 ± 0.269
0.0ProXaa: 0.0 ± 0.0
Gln
2.272GlnAla: 2.272 ± 0.982
0.284GlnCys: 0.284 ± 0.165
1.704GlnAsp: 1.704 ± 0.647
1.42GlnGlu: 1.42 ± 0.442
0.852GlnPhe: 0.852 ± 0.357
0.852GlnGly: 0.852 ± 0.357
0.284GlnHis: 0.284 ± 0.165
2.84GlnIle: 2.84 ± 0.959
1.704GlnLys: 1.704 ± 0.847
2.272GlnLeu: 2.272 ± 0.651
0.284GlnMet: 0.284 ± 0.376
0.852GlnAsn: 0.852 ± 0.358
0.284GlnPro: 0.284 ± 0.165
0.568GlnGln: 0.568 ± 0.652
1.988GlnArg: 1.988 ± 0.757
3.692GlnSer: 3.692 ± 1.919
1.136GlnThr: 1.136 ± 0.415
1.988GlnVal: 1.988 ± 0.84
0.0GlnTrp: 0.0 ± 0.0
0.852GlnTyr: 0.852 ± 0.357
0.0GlnXaa: 0.0 ± 0.0
Arg
0.852ArgAla: 0.852 ± 0.443
0.568ArgCys: 0.568 ± 0.331
2.556ArgAsp: 2.556 ± 0.567
3.692ArgGlu: 3.692 ± 0.806
2.556ArgPhe: 2.556 ± 1.489
2.272ArgGly: 2.272 ± 0.305
1.136ArgHis: 1.136 ± 0.662
2.272ArgIle: 2.272 ± 0.822
5.112ArgLys: 5.112 ± 0.801
3.976ArgLeu: 3.976 ± 1.045
0.568ArgMet: 0.568 ± 0.372
3.408ArgAsn: 3.408 ± 0.97
1.988ArgPro: 1.988 ± 1.141
1.988ArgGln: 1.988 ± 0.631
2.84ArgArg: 2.84 ± 0.933
3.124ArgSer: 3.124 ± 1.078
2.556ArgThr: 2.556 ± 0.514
2.556ArgVal: 2.556 ± 1.063
0.852ArgTrp: 0.852 ± 0.562
3.124ArgTyr: 3.124 ± 1.463
0.0ArgXaa: 0.0 ± 0.0
Ser
2.556SerAla: 2.556 ± 1.56
0.568SerCys: 0.568 ± 0.331
6.248SerAsp: 6.248 ± 2.007
3.124SerGlu: 3.124 ± 0.522
3.692SerPhe: 3.692 ± 1.125
2.556SerGly: 2.556 ± 0.882
1.42SerHis: 1.42 ± 0.644
6.532SerIle: 6.532 ± 1.668
6.532SerLys: 6.532 ± 0.487
4.828SerLeu: 4.828 ± 1.676
1.136SerMet: 1.136 ± 0.578
6.532SerAsn: 6.532 ± 2.937
1.704SerPro: 1.704 ± 0.762
1.988SerGln: 1.988 ± 1.38
3.976SerArg: 3.976 ± 1.428
7.1SerSer: 7.1 ± 1.548
4.26SerThr: 4.26 ± 0.959
5.396SerVal: 5.396 ± 1.332
0.852SerTrp: 0.852 ± 0.357
3.124SerTyr: 3.124 ± 0.9
0.0SerXaa: 0.0 ± 0.0
Thr
2.272ThrAla: 2.272 ± 0.842
1.136ThrCys: 1.136 ± 1.056
2.272ThrAsp: 2.272 ± 0.305
3.976ThrGlu: 3.976 ± 0.609
1.704ThrPhe: 1.704 ± 0.581
2.84ThrGly: 2.84 ± 0.969
1.704ThrHis: 1.704 ± 0.571
5.964ThrIle: 5.964 ± 1.891
5.964ThrLys: 5.964 ± 2.115
4.26ThrLeu: 4.26 ± 1.527
0.568ThrMet: 0.568 ± 0.331
3.408ThrAsn: 3.408 ± 0.85
2.272ThrPro: 2.272 ± 0.671
1.136ThrGln: 1.136 ± 0.415
2.272ThrArg: 2.272 ± 0.711
4.828ThrSer: 4.828 ± 1.524
3.124ThrThr: 3.124 ± 1.255
3.976ThrVal: 3.976 ± 0.869
0.852ThrTrp: 0.852 ± 0.358
2.272ThrTyr: 2.272 ± 0.471
0.0ThrXaa: 0.0 ± 0.0
Val
0.568ValAla: 0.568 ± 0.328
1.988ValCys: 1.988 ± 0.551
2.84ValAsp: 2.84 ± 1.787
3.124ValGlu: 3.124 ± 0.858
3.124ValPhe: 3.124 ± 1.035
3.408ValGly: 3.408 ± 1.245
0.852ValHis: 0.852 ± 0.358
6.248ValIle: 6.248 ± 0.824
4.26ValLys: 4.26 ± 1.017
4.26ValLeu: 4.26 ± 1.002
1.42ValMet: 1.42 ± 1.042
4.26ValAsn: 4.26 ± 1.032
0.852ValPro: 0.852 ± 0.357
1.704ValGln: 1.704 ± 0.721
3.124ValArg: 3.124 ± 1.255
1.136ValSer: 1.136 ± 1.023
1.988ValThr: 1.988 ± 1.072
1.988ValVal: 1.988 ± 0.728
0.284ValTrp: 0.284 ± 0.165
1.988ValTyr: 1.988 ± 0.535
0.0ValXaa: 0.0 ± 0.0
Trp
0.284TrpAla: 0.284 ± 0.451
0.0TrpCys: 0.0 ± 0.0
0.852TrpAsp: 0.852 ± 0.496
1.136TrpGlu: 1.136 ± 0.662
0.284TrpPhe: 0.284 ± 0.165
0.284TrpGly: 0.284 ± 0.165
0.568TrpHis: 0.568 ± 0.331
0.852TrpIle: 0.852 ± 0.851
0.568TrpLys: 0.568 ± 0.328
1.988TrpLeu: 1.988 ± 0.757
0.568TrpMet: 0.568 ± 0.561
1.704TrpAsn: 1.704 ± 0.721
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.284TrpArg: 0.284 ± 0.165
0.568TrpSer: 0.568 ± 0.328
0.0TrpThr: 0.0 ± 0.0
0.568TrpVal: 0.568 ± 0.819
0.0TrpTrp: 0.0 ± 0.0
0.568TrpTyr: 0.568 ± 0.607
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.136TyrAla: 1.136 ± 0.744
0.568TyrCys: 0.568 ± 0.752
2.556TyrAsp: 2.556 ± 0.662
2.556TyrGlu: 2.556 ± 1.063
1.42TyrPhe: 1.42 ± 0.521
1.136TyrGly: 1.136 ± 0.353
1.42TyrHis: 1.42 ± 0.667
5.964TyrIle: 5.964 ± 1.44
4.26TyrLys: 4.26 ± 1.316
7.952TyrLeu: 7.952 ± 0.915
0.852TyrMet: 0.852 ± 0.622
4.828TyrAsn: 4.828 ± 1.808
1.704TyrPro: 1.704 ± 0.721
2.84TyrGln: 2.84 ± 0.994
2.556TyrArg: 2.556 ± 0.812
3.692TyrSer: 3.692 ± 1.221
3.408TyrThr: 3.408 ± 1.063
2.556TyrVal: 2.556 ± 0.83
1.136TyrTrp: 1.136 ± 0.656
2.556TyrTyr: 2.556 ± 0.537
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3522 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski