Amino acid dipepetide frequency for Mosquitoe x virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.851AlaAla: 5.851 ± 0.548
0.488AlaCys: 0.488 ± 0.345
2.925AlaAsp: 2.925 ± 0.061
2.438AlaGlu: 2.438 ± 0.385
2.438AlaPhe: 2.438 ± 0.953
4.388AlaGly: 4.388 ± 0.243
0.488AlaHis: 0.488 ± 0.324
2.438AlaIle: 2.438 ± 0.385
4.876AlaLys: 4.876 ± 1.439
7.801AlaLeu: 7.801 ± 0.162
2.438AlaMet: 2.438 ± 1.054
2.925AlaAsn: 2.925 ± 0.73
2.925AlaPro: 2.925 ± 0.608
2.925AlaGln: 2.925 ± 0.73
2.925AlaArg: 2.925 ± 0.608
5.363AlaSer: 5.363 ± 1.561
2.438AlaThr: 2.438 ± 0.284
3.901AlaVal: 3.901 ± 1.926
0.488AlaTrp: 0.488 ± 0.324
2.438AlaTyr: 2.438 ± 1.723
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.488CysAsp: 0.488 ± 0.324
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.488CysIle: 0.488 ± 0.345
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.488CysPro: 0.488 ± 0.345
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.488CysThr: 0.488 ± 0.345
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.488CysTyr: 0.488 ± 0.324
0.0CysXaa: 0.0 ± 0.0
Asp
1.95AspAla: 1.95 ± 0.04
0.0AspCys: 0.0 ± 0.0
1.95AspAsp: 1.95 ± 0.629
3.901AspGlu: 3.901 ± 0.081
1.95AspPhe: 1.95 ± 0.04
2.925AspGly: 2.925 ± 0.608
0.488AspHis: 0.488 ± 0.345
4.388AspIle: 4.388 ± 1.763
0.488AspLys: 0.488 ± 0.324
2.925AspLeu: 2.925 ± 0.73
1.95AspMet: 1.95 ± 1.378
1.95AspAsn: 1.95 ± 0.04
2.925AspPro: 2.925 ± 0.608
3.413AspGln: 3.413 ± 1.602
2.438AspArg: 2.438 ± 0.284
3.901AspSer: 3.901 ± 0.081
2.925AspThr: 2.925 ± 0.608
4.388AspVal: 4.388 ± 0.243
0.975AspTrp: 0.975 ± 0.02
1.463AspTyr: 1.463 ± 0.973
0.0AspXaa: 0.0 ± 0.0
Glu
4.388GluAla: 4.388 ± 1.763
0.0GluCys: 0.0 ± 0.0
4.388GluAsp: 4.388 ± 0.243
3.413GluGlu: 3.413 ± 1.074
2.925GluPhe: 2.925 ± 0.608
2.925GluGly: 2.925 ± 1.399
1.95GluHis: 1.95 ± 0.709
2.438GluIle: 2.438 ± 1.054
3.901GluLys: 3.901 ± 0.75
6.826GluLeu: 6.826 ± 1.48
0.488GluMet: 0.488 ± 0.324
4.388GluAsn: 4.388 ± 0.426
1.95GluPro: 1.95 ± 0.04
2.925GluGln: 2.925 ± 1.399
3.413GluArg: 3.413 ± 0.264
2.925GluSer: 2.925 ± 1.946
2.438GluThr: 2.438 ± 0.385
3.901GluVal: 3.901 ± 0.081
1.463GluTrp: 1.463 ± 0.365
3.413GluTyr: 3.413 ± 1.074
0.0GluXaa: 0.0 ± 0.0
Phe
0.975PheAla: 0.975 ± 0.02
0.0PheCys: 0.0 ± 0.0
1.95PheAsp: 1.95 ± 0.629
0.488PheGlu: 0.488 ± 0.345
0.488PhePhe: 0.488 ± 0.324
1.95PheGly: 1.95 ± 0.629
1.463PheHis: 1.463 ± 0.973
1.463PheIle: 1.463 ± 0.973
2.438PheLys: 2.438 ± 1.723
3.901PheLeu: 3.901 ± 1.257
0.488PheMet: 0.488 ± 0.345
2.925PheAsn: 2.925 ± 0.608
1.463PhePro: 1.463 ± 0.365
0.975PheGln: 0.975 ± 0.02
1.95PheArg: 1.95 ± 1.378
4.388PheSer: 4.388 ± 2.432
2.438PheThr: 2.438 ± 0.284
1.463PheVal: 1.463 ± 0.304
0.975PheTrp: 0.975 ± 0.649
0.488PheTyr: 0.488 ± 0.324
0.0PheXaa: 0.0 ± 0.0
Gly
3.413GlyAla: 3.413 ± 0.933
0.0GlyCys: 0.0 ± 0.0
1.463GlyAsp: 1.463 ± 0.973
6.338GlyGlu: 6.338 ± 0.466
2.438GlyPhe: 2.438 ± 0.284
2.925GlyGly: 2.925 ± 0.608
1.463GlyHis: 1.463 ± 0.365
3.901GlyIle: 3.901 ± 1.926
2.438GlyLys: 2.438 ± 0.385
7.314GlyLeu: 7.314 ± 0.852
1.463GlyMet: 1.463 ± 1.034
3.901GlyAsn: 3.901 ± 1.257
1.95GlyPro: 1.95 ± 1.298
5.851GlyGln: 5.851 ± 0.121
2.925GlyArg: 2.925 ± 0.608
6.338GlySer: 6.338 ± 1.804
3.413GlyThr: 3.413 ± 2.271
4.388GlyVal: 4.388 ± 0.912
1.95GlyTrp: 1.95 ± 1.378
1.95GlyTyr: 1.95 ± 0.04
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.438HisGlu: 2.438 ± 0.284
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.488HisHis: 0.488 ± 0.345
1.95HisIle: 1.95 ± 0.629
0.975HisLys: 0.975 ± 0.689
1.463HisLeu: 1.463 ± 0.365
0.0HisMet: 0.0 ± 0.0
0.488HisAsn: 0.488 ± 0.345
0.0HisPro: 0.0 ± 0.0
1.463HisGln: 1.463 ± 0.304
0.975HisArg: 0.975 ± 0.02
2.438HisSer: 2.438 ± 0.385
0.488HisThr: 0.488 ± 0.345
1.463HisVal: 1.463 ± 0.304
0.975HisTrp: 0.975 ± 0.02
1.463HisTyr: 1.463 ± 0.973
0.0HisXaa: 0.0 ± 0.0
Ile
4.388IleAla: 4.388 ± 0.426
0.0IleCys: 0.0 ± 0.0
2.438IleAsp: 2.438 ± 0.385
2.925IleGlu: 2.925 ± 2.068
0.488IlePhe: 0.488 ± 0.345
4.876IleGly: 4.876 ± 1.237
0.0IleHis: 0.0 ± 0.0
2.438IleIle: 2.438 ± 0.284
4.876IleLys: 4.876 ± 0.77
4.876IleLeu: 4.876 ± 1.439
2.438IleMet: 2.438 ± 1.47
2.438IleAsn: 2.438 ± 0.284
3.413IlePro: 3.413 ± 1.602
2.438IleGln: 2.438 ± 0.284
3.901IleArg: 3.901 ± 0.75
7.314IleSer: 7.314 ± 0.852
5.851IleThr: 5.851 ± 0.121
2.438IleVal: 2.438 ± 0.284
0.975IleTrp: 0.975 ± 0.02
1.95IleTyr: 1.95 ± 0.04
0.0IleXaa: 0.0 ± 0.0
Lys
2.925LysAla: 2.925 ± 0.608
0.0LysCys: 0.0 ± 0.0
2.925LysAsp: 2.925 ± 1.399
2.925LysGlu: 2.925 ± 0.73
1.463LysPhe: 1.463 ± 1.034
4.388LysGly: 4.388 ± 2.432
0.0LysHis: 0.0 ± 0.0
2.438LysIle: 2.438 ± 0.284
3.413LysLys: 3.413 ± 1.074
5.851LysLeu: 5.851 ± 0.79
1.95LysMet: 1.95 ± 0.629
2.438LysAsn: 2.438 ± 1.054
2.438LysPro: 2.438 ± 1.054
1.463LysGln: 1.463 ± 0.304
3.901LysArg: 3.901 ± 0.75
5.363LysSer: 5.363 ± 1.115
2.925LysThr: 2.925 ± 0.608
4.388LysVal: 4.388 ± 0.426
0.488LysTrp: 0.488 ± 0.345
2.438LysTyr: 2.438 ± 1.054
0.0LysXaa: 0.0 ± 0.0
Leu
5.851LeuAla: 5.851 ± 0.548
0.0LeuCys: 0.0 ± 0.0
4.388LeuAsp: 4.388 ± 0.243
5.851LeuGlu: 5.851 ± 0.79
3.413LeuPhe: 3.413 ± 0.405
7.801LeuGly: 7.801 ± 0.831
0.488LeuHis: 0.488 ± 0.324
5.363LeuIle: 5.363 ± 0.446
6.338LeuLys: 6.338 ± 0.466
8.289LeuLeu: 8.289 ± 1.844
1.95LeuMet: 1.95 ± 0.709
5.851LeuAsn: 5.851 ± 0.121
6.338LeuPro: 6.338 ± 0.466
3.901LeuGln: 3.901 ± 1.257
2.925LeuArg: 2.925 ± 0.061
5.851LeuSer: 5.851 ± 1.217
7.314LeuThr: 7.314 ± 1.155
5.851LeuVal: 5.851 ± 0.121
0.0LeuTrp: 0.0 ± 0.0
3.413LeuTyr: 3.413 ± 1.074
0.0LeuXaa: 0.0 ± 0.0
Met
1.463MetAla: 1.463 ± 0.304
0.0MetCys: 0.0 ± 0.0
1.463MetAsp: 1.463 ± 0.365
0.975MetGlu: 0.975 ± 0.689
0.488MetPhe: 0.488 ± 0.324
2.925MetGly: 2.925 ± 1.399
0.488MetHis: 0.488 ± 0.345
2.438MetIle: 2.438 ± 0.284
2.438MetLys: 2.438 ± 0.385
3.901MetLeu: 3.901 ± 1.419
1.463MetMet: 1.463 ± 0.365
2.438MetAsn: 2.438 ± 0.284
0.975MetPro: 0.975 ± 0.02
1.463MetGln: 1.463 ± 0.304
0.975MetArg: 0.975 ± 0.649
2.438MetSer: 2.438 ± 0.385
2.925MetThr: 2.925 ± 0.608
2.438MetVal: 2.438 ± 0.385
0.0MetTrp: 0.0 ± 0.0
0.975MetTyr: 0.975 ± 0.689
0.0MetXaa: 0.0 ± 0.0
Asn
2.438AsnAla: 2.438 ± 0.953
0.488AsnCys: 0.488 ± 0.345
2.438AsnAsp: 2.438 ± 1.054
1.463AsnGlu: 1.463 ± 0.304
0.975AsnPhe: 0.975 ± 0.689
3.413AsnGly: 3.413 ± 1.602
1.463AsnHis: 1.463 ± 0.365
2.438AsnIle: 2.438 ± 0.385
4.388AsnLys: 4.388 ± 0.426
4.388AsnLeu: 4.388 ± 2.25
0.975AsnMet: 0.975 ± 0.261
3.413AsnAsn: 3.413 ± 0.264
6.338AsnPro: 6.338 ± 0.872
1.463AsnGln: 1.463 ± 0.365
1.95AsnArg: 1.95 ± 0.04
3.413AsnSer: 3.413 ± 0.933
3.413AsnThr: 3.413 ± 0.933
6.338AsnVal: 6.338 ± 0.872
0.488AsnTrp: 0.488 ± 0.324
2.925AsnTyr: 2.925 ± 0.608
0.0AsnXaa: 0.0 ± 0.0
Pro
1.95ProAla: 1.95 ± 0.04
0.975ProCys: 0.975 ± 0.02
1.95ProAsp: 1.95 ± 0.04
5.363ProGlu: 5.363 ± 0.446
3.901ProPhe: 3.901 ± 0.081
1.463ProGly: 1.463 ± 0.365
0.488ProHis: 0.488 ± 0.324
5.363ProIle: 5.363 ± 0.892
2.438ProLys: 2.438 ± 1.054
2.925ProLeu: 2.925 ± 0.061
0.975ProMet: 0.975 ± 0.02
2.925ProAsn: 2.925 ± 1.277
3.901ProPro: 3.901 ± 0.081
3.413ProGln: 3.413 ± 0.933
4.876ProArg: 4.876 ± 1.439
3.901ProSer: 3.901 ± 1.257
4.876ProThr: 4.876 ± 0.568
3.413ProVal: 3.413 ± 0.933
1.463ProTrp: 1.463 ± 1.034
2.925ProTyr: 2.925 ± 0.061
0.0ProXaa: 0.0 ± 0.0
Gln
2.925GlnAla: 2.925 ± 0.061
0.0GlnCys: 0.0 ± 0.0
2.438GlnAsp: 2.438 ± 0.284
4.388GlnGlu: 4.388 ± 0.912
1.463GlnPhe: 1.463 ± 0.304
6.338GlnGly: 6.338 ± 1.541
0.0GlnHis: 0.0 ± 0.0
2.438GlnIle: 2.438 ± 0.284
1.463GlnLys: 1.463 ± 0.304
3.901GlnLeu: 3.901 ± 0.081
1.95GlnMet: 1.95 ± 1.298
2.925GlnAsn: 2.925 ± 0.608
2.925GlnPro: 2.925 ± 0.061
1.95GlnGln: 1.95 ± 0.04
2.438GlnArg: 2.438 ± 1.054
1.95GlnSer: 1.95 ± 0.629
0.975GlnThr: 0.975 ± 0.02
2.438GlnVal: 2.438 ± 0.385
0.0GlnTrp: 0.0 ± 0.0
2.438GlnTyr: 2.438 ± 0.284
0.0GlnXaa: 0.0 ± 0.0
Arg
2.925ArgAla: 2.925 ± 0.061
0.0ArgCys: 0.0 ± 0.0
0.488ArgAsp: 0.488 ± 0.345
6.826ArgGlu: 6.826 ± 1.48
0.975ArgPhe: 0.975 ± 0.689
2.438ArgGly: 2.438 ± 0.284
0.975ArgHis: 0.975 ± 0.649
4.388ArgIle: 4.388 ± 0.426
2.925ArgLys: 2.925 ± 0.73
5.363ArgLeu: 5.363 ± 0.892
2.438ArgMet: 2.438 ± 1.723
3.413ArgAsn: 3.413 ± 0.264
2.925ArgPro: 2.925 ± 1.399
1.95ArgGln: 1.95 ± 0.04
3.901ArgArg: 3.901 ± 0.588
2.925ArgSer: 2.925 ± 0.608
2.438ArgThr: 2.438 ± 0.284
1.95ArgVal: 1.95 ± 0.629
0.488ArgTrp: 0.488 ± 0.324
0.488ArgTyr: 0.488 ± 0.345
0.0ArgXaa: 0.0 ± 0.0
Ser
6.338SerAla: 6.338 ± 0.466
0.0SerCys: 0.0 ± 0.0
4.388SerAsp: 4.388 ± 0.426
3.413SerGlu: 3.413 ± 0.405
2.438SerPhe: 2.438 ± 0.284
6.338SerGly: 6.338 ± 2.21
1.463SerHis: 1.463 ± 0.304
6.338SerIle: 6.338 ± 1.135
3.901SerLys: 3.901 ± 0.75
8.289SerLeu: 8.289 ± 1.175
3.413SerMet: 3.413 ± 0.264
5.851SerAsn: 5.851 ± 1.886
4.388SerPro: 4.388 ± 0.426
2.438SerGln: 2.438 ± 1.622
1.95SerArg: 1.95 ± 0.04
11.214SerSer: 11.214 ± 0.567
4.876SerThr: 4.876 ± 0.77
6.338SerVal: 6.338 ± 2.879
0.0SerTrp: 0.0 ± 0.0
2.438SerTyr: 2.438 ± 0.284
0.0SerXaa: 0.0 ± 0.0
Thr
4.388ThrAla: 4.388 ± 0.426
0.488ThrCys: 0.488 ± 0.324
2.438ThrAsp: 2.438 ± 0.284
3.413ThrGlu: 3.413 ± 0.405
2.925ThrPhe: 2.925 ± 0.608
3.901ThrGly: 3.901 ± 1.257
1.95ThrHis: 1.95 ± 0.709
4.876ThrIle: 4.876 ± 0.101
1.95ThrLys: 1.95 ± 0.709
4.388ThrLeu: 4.388 ± 0.243
2.925ThrMet: 2.925 ± 0.608
2.438ThrAsn: 2.438 ± 0.953
6.338ThrPro: 6.338 ± 0.466
3.413ThrGln: 3.413 ± 0.933
4.876ThrArg: 4.876 ± 0.77
6.338ThrSer: 6.338 ± 0.203
2.438ThrThr: 2.438 ± 1.054
2.925ThrVal: 2.925 ± 1.277
0.488ThrTrp: 0.488 ± 0.324
0.975ThrTyr: 0.975 ± 0.02
0.0ThrXaa: 0.0 ± 0.0
Val
5.363ValAla: 5.363 ± 0.223
0.0ValCys: 0.0 ± 0.0
3.901ValAsp: 3.901 ± 1.257
2.438ValGlu: 2.438 ± 1.054
2.925ValPhe: 2.925 ± 0.061
3.901ValGly: 3.901 ± 1.926
1.463ValHis: 1.463 ± 0.304
1.95ValIle: 1.95 ± 0.04
3.901ValLys: 3.901 ± 0.588
3.413ValLeu: 3.413 ± 0.264
1.95ValMet: 1.95 ± 0.04
2.438ValAsn: 2.438 ± 0.953
6.338ValPro: 6.338 ± 1.541
2.438ValGln: 2.438 ± 1.054
1.95ValArg: 1.95 ± 1.298
6.338ValSer: 6.338 ± 1.541
4.388ValThr: 4.388 ± 1.581
2.925ValVal: 2.925 ± 0.061
1.95ValTrp: 1.95 ± 0.04
2.925ValTyr: 2.925 ± 0.061
0.0ValXaa: 0.0 ± 0.0
Trp
1.463TrpAla: 1.463 ± 0.365
0.0TrpCys: 0.0 ± 0.0
0.975TrpAsp: 0.975 ± 0.02
0.488TrpGlu: 0.488 ± 0.324
0.488TrpPhe: 0.488 ± 0.324
0.0TrpGly: 0.0 ± 0.0
0.975TrpHis: 0.975 ± 0.02
0.488TrpIle: 0.488 ± 0.324
0.0TrpLys: 0.0 ± 0.0
1.95TrpLeu: 1.95 ± 0.709
0.0TrpMet: 0.0 ± 0.0
0.488TrpAsn: 0.488 ± 0.345
0.488TrpPro: 0.488 ± 0.345
0.0TrpGln: 0.0 ± 0.0
0.488TrpArg: 0.488 ± 0.345
1.95TrpSer: 1.95 ± 0.629
2.438TrpThr: 2.438 ± 0.385
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.488TrpTyr: 0.488 ± 0.345
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.901TyrAla: 3.901 ± 0.081
0.0TyrCys: 0.0 ± 0.0
3.901TyrAsp: 3.901 ± 0.588
0.975TyrGlu: 0.975 ± 0.02
0.488TyrPhe: 0.488 ± 0.345
2.925TyrGly: 2.925 ± 0.608
0.975TyrHis: 0.975 ± 0.02
2.438TyrIle: 2.438 ± 0.284
0.975TyrLys: 0.975 ± 0.689
3.413TyrLeu: 3.413 ± 0.405
2.925TyrMet: 2.925 ± 1.399
1.463TyrAsn: 1.463 ± 0.304
0.975TyrPro: 0.975 ± 0.02
1.463TyrGln: 1.463 ± 0.973
1.463TyrArg: 1.463 ± 0.365
1.463TyrSer: 1.463 ± 1.034
4.388TyrThr: 4.388 ± 1.094
1.95TyrVal: 1.95 ± 0.04
0.0TyrTrp: 0.0 ± 0.0
1.463TyrTyr: 1.463 ± 0.365
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2052 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski