Amino acid dipepetide frequency for Mount Elgon bat virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.68AlaAla: 1.68 ± 1.026
1.68AlaCys: 1.68 ± 0.695
3.08AlaAsp: 3.08 ± 0.869
2.24AlaGlu: 2.24 ± 1.263
1.96AlaPhe: 1.96 ± 0.795
1.96AlaGly: 1.96 ± 0.654
1.12AlaHis: 1.12 ± 0.675
2.52AlaIle: 2.52 ± 0.475
3.359AlaLys: 3.359 ± 2.059
3.919AlaLeu: 3.919 ± 1.333
0.56AlaMet: 0.56 ± 0.342
2.24AlaAsn: 2.24 ± 1.038
0.56AlaPro: 0.56 ± 0.342
0.84AlaGln: 0.84 ± 0.507
1.96AlaArg: 1.96 ± 1.018
2.52AlaSer: 2.52 ± 0.689
3.359AlaThr: 3.359 ± 1.019
1.12AlaVal: 1.12 ± 0.323
0.56AlaTrp: 0.56 ± 0.335
1.96AlaTyr: 1.96 ± 1.018
0.0AlaXaa: 0.0 ± 0.0
Cys
0.28CysAla: 0.28 ± 0.4
0.84CysCys: 0.84 ± 0.349
1.12CysAsp: 1.12 ± 0.432
1.4CysGlu: 1.4 ± 0.554
0.84CysPhe: 0.84 ± 0.644
1.4CysGly: 1.4 ± 0.554
0.84CysHis: 0.84 ± 0.408
1.68CysIle: 1.68 ± 0.695
1.68CysLys: 1.68 ± 0.566
3.08CysLeu: 3.08 ± 1.107
0.0CysMet: 0.0 ± 0.0
1.96CysAsn: 1.96 ± 0.845
1.68CysPro: 1.68 ± 0.613
0.28CysGln: 0.28 ± 0.167
0.56CysArg: 0.56 ± 0.805
1.4CysSer: 1.4 ± 0.509
0.28CysThr: 0.28 ± 0.167
0.56CysVal: 0.56 ± 0.335
0.28CysTrp: 0.28 ± 0.167
1.96CysTyr: 1.96 ± 0.867
0.0CysXaa: 0.0 ± 0.0
Asp
3.359AspAla: 3.359 ± 1.576
1.12AspCys: 1.12 ± 0.591
5.039AspAsp: 5.039 ± 2.757
4.479AspGlu: 4.479 ± 0.444
1.96AspPhe: 1.96 ± 0.751
3.08AspGly: 3.08 ± 1.195
1.68AspHis: 1.68 ± 0.477
3.639AspIle: 3.639 ± 0.737
3.919AspLys: 3.919 ± 1.488
8.959AspLeu: 8.959 ± 0.891
1.68AspMet: 1.68 ± 0.378
2.24AspAsn: 2.24 ± 1.061
2.24AspPro: 2.24 ± 1.036
1.4AspGln: 1.4 ± 0.838
1.4AspArg: 1.4 ± 0.312
2.52AspSer: 2.52 ± 1.217
2.52AspThr: 2.52 ± 0.502
3.359AspVal: 3.359 ± 0.886
1.68AspTrp: 1.68 ± 0.788
2.52AspTyr: 2.52 ± 0.861
0.0AspXaa: 0.0 ± 0.0
Glu
3.08GluAla: 3.08 ± 0.75
1.12GluCys: 1.12 ± 1.16
3.08GluAsp: 3.08 ± 1.191
7.839GluGlu: 7.839 ± 1.626
3.359GluPhe: 3.359 ± 1.694
3.08GluGly: 3.08 ± 1.245
1.4GluHis: 1.4 ± 0.583
5.879GluIle: 5.879 ± 0.713
4.759GluLys: 4.759 ± 2.022
4.759GluLeu: 4.759 ± 1.11
1.4GluMet: 1.4 ± 0.506
3.639GluAsn: 3.639 ± 1.107
2.24GluPro: 2.24 ± 0.922
1.12GluGln: 1.12 ± 1.407
3.08GluArg: 3.08 ± 0.699
3.919GluSer: 3.919 ± 0.528
5.319GluThr: 5.319 ± 1.294
4.479GluVal: 4.479 ± 2.335
1.12GluTrp: 1.12 ± 0.735
2.52GluTyr: 2.52 ± 0.638
0.0GluXaa: 0.0 ± 0.0
Phe
0.84PheAla: 0.84 ± 0.361
1.12PheCys: 1.12 ± 0.735
1.96PheAsp: 1.96 ± 0.495
1.96PheGlu: 1.96 ± 0.585
2.24PhePhe: 2.24 ± 1.001
3.359PheGly: 3.359 ± 1.272
0.56PheHis: 0.56 ± 0.338
1.68PheIle: 1.68 ± 0.781
5.319PheLys: 5.319 ± 1.501
4.199PheLeu: 4.199 ± 0.647
0.84PheMet: 0.84 ± 0.725
2.52PheAsn: 2.52 ± 0.67
2.24PhePro: 2.24 ± 0.863
1.4PheGln: 1.4 ± 0.661
2.8PheArg: 2.8 ± 0.951
2.8PheSer: 2.8 ± 0.787
0.84PheThr: 0.84 ± 0.644
0.84PheVal: 0.84 ± 0.502
0.56PheTrp: 0.56 ± 0.335
1.68PheTyr: 1.68 ± 0.715
0.0PheXaa: 0.0 ± 0.0
Gly
2.24GlyAla: 2.24 ± 1.001
0.28GlyCys: 0.28 ± 0.167
3.359GlyAsp: 3.359 ± 0.733
1.96GlyGlu: 1.96 ± 0.908
1.96GlyPhe: 1.96 ± 0.862
3.639GlyGly: 3.639 ± 0.779
0.28GlyHis: 0.28 ± 0.167
3.919GlyIle: 3.919 ± 0.844
3.919GlyLys: 3.919 ± 0.958
8.679GlyLeu: 8.679 ± 1.401
1.4GlyMet: 1.4 ± 0.615
3.639GlyAsn: 3.639 ± 1.27
2.8GlyPro: 2.8 ± 0.759
1.4GlyGln: 1.4 ± 0.837
1.68GlyArg: 1.68 ± 0.695
3.359GlySer: 3.359 ± 0.601
3.639GlyThr: 3.639 ± 1.527
3.08GlyVal: 3.08 ± 1.771
0.84GlyTrp: 0.84 ± 0.349
3.08GlyTyr: 3.08 ± 1.52
0.0GlyXaa: 0.0 ± 0.0
His
1.68HisAla: 1.68 ± 1.222
0.28HisCys: 0.28 ± 0.167
1.12HisAsp: 1.12 ± 1.121
0.56HisGlu: 0.56 ± 0.335
1.4HisPhe: 1.4 ± 0.554
0.28HisGly: 0.28 ± 0.402
0.84HisHis: 0.84 ± 1.207
3.08HisIle: 3.08 ± 1.209
2.8HisLys: 2.8 ± 1.735
1.96HisLeu: 1.96 ± 0.495
0.0HisMet: 0.0 ± 0.0
1.12HisAsn: 1.12 ± 0.432
1.96HisPro: 1.96 ± 0.377
1.4HisGln: 1.4 ± 0.57
1.68HisArg: 1.68 ± 0.477
0.56HisSer: 0.56 ± 0.338
1.12HisThr: 1.12 ± 0.591
0.56HisVal: 0.56 ± 0.342
1.12HisTrp: 1.12 ± 0.565
1.12HisTyr: 1.12 ± 0.669
0.0HisXaa: 0.0 ± 0.0
Ile
2.24IleAla: 2.24 ± 0.893
3.08IleCys: 3.08 ± 0.841
6.159IleAsp: 6.159 ± 1.771
5.879IleGlu: 5.879 ± 1.528
2.52IlePhe: 2.52 ± 1.218
6.159IleGly: 6.159 ± 1.3
1.68IleHis: 1.68 ± 1.013
5.599IleIle: 5.599 ± 1.388
6.719IleLys: 6.719 ± 1.501
6.999IleLeu: 6.999 ± 0.462
1.68IleMet: 1.68 ± 0.781
6.439IleAsn: 6.439 ± 0.801
3.919IlePro: 3.919 ± 1.236
2.24IleGln: 2.24 ± 0.643
5.879IleArg: 5.879 ± 1.504
5.039IleSer: 5.039 ± 0.996
5.319IleThr: 5.319 ± 1.263
2.52IleVal: 2.52 ± 0.638
1.12IleTrp: 1.12 ± 0.432
3.08IleTyr: 3.08 ± 0.731
0.0IleXaa: 0.0 ± 0.0
Lys
1.96LysAla: 1.96 ± 0.781
1.96LysCys: 1.96 ± 0.845
3.919LysAsp: 3.919 ± 1.733
4.759LysGlu: 4.759 ± 1.282
3.08LysPhe: 3.08 ± 0.475
2.52LysGly: 2.52 ± 1.177
1.68LysHis: 1.68 ± 0.826
9.239LysIle: 9.239 ± 0.972
8.399LysLys: 8.399 ± 2.508
7.839LysLeu: 7.839 ± 1.224
3.08LysMet: 3.08 ± 0.821
3.08LysAsn: 3.08 ± 1.719
4.759LysPro: 4.759 ± 1.887
1.12LysGln: 1.12 ± 0.417
4.759LysArg: 4.759 ± 1.938
3.359LysSer: 3.359 ± 1.232
4.759LysThr: 4.759 ± 0.236
3.639LysVal: 3.639 ± 0.32
2.24LysTrp: 2.24 ± 0.567
2.52LysTyr: 2.52 ± 0.813
0.0LysXaa: 0.0 ± 0.0
Leu
4.199LeuAla: 4.199 ± 1.126
1.68LeuCys: 1.68 ± 0.695
7.559LeuAsp: 7.559 ± 2.228
7.279LeuGlu: 7.279 ± 1.506
4.199LeuPhe: 4.199 ± 1.456
4.759LeuGly: 4.759 ± 0.702
3.359LeuHis: 3.359 ± 0.733
11.198LeuIle: 11.198 ± 2.482
6.719LeuLys: 6.719 ± 0.915
8.119LeuLeu: 8.119 ± 1.147
2.8LeuMet: 2.8 ± 0.339
5.599LeuAsn: 5.599 ± 1.482
3.919LeuPro: 3.919 ± 1.982
3.639LeuGln: 3.639 ± 0.956
7.559LeuArg: 7.559 ± 1.729
7.839LeuSer: 7.839 ± 1.857
6.439LeuThr: 6.439 ± 1.386
1.4LeuVal: 1.4 ± 0.312
1.4LeuTrp: 1.4 ± 0.312
3.919LeuTyr: 3.919 ± 0.78
0.0LeuXaa: 0.0 ± 0.0
Met
0.84MetAla: 0.84 ± 0.361
1.12MetCys: 1.12 ± 0.432
1.12MetAsp: 1.12 ± 0.323
1.68MetGlu: 1.68 ± 1.478
1.4MetPhe: 1.4 ± 0.634
1.4MetGly: 1.4 ± 0.873
0.28MetHis: 0.28 ± 0.167
2.24MetIle: 2.24 ± 1.339
1.96MetLys: 1.96 ± 0.997
1.68MetLeu: 1.68 ± 0.622
0.84MetMet: 0.84 ± 0.502
2.52MetAsn: 2.52 ± 0.583
0.0MetPro: 0.0 ± 0.0
0.28MetGln: 0.28 ± 0.4
0.84MetArg: 0.84 ± 0.408
1.96MetSer: 1.96 ± 0.554
1.4MetThr: 1.4 ± 0.511
0.56MetVal: 0.56 ± 0.338
0.0MetTrp: 0.0 ± 0.0
0.28MetTyr: 0.28 ± 0.4
0.0MetXaa: 0.0 ± 0.0
Asn
2.8AsnAla: 2.8 ± 0.76
2.24AsnCys: 2.24 ± 0.893
3.639AsnAsp: 3.639 ± 1.096
2.8AsnGlu: 2.8 ± 0.79
1.4AsnPhe: 1.4 ± 0.837
3.639AsnGly: 3.639 ± 1.521
1.68AsnHis: 1.68 ± 0.565
3.639AsnIle: 3.639 ± 0.851
4.199AsnLys: 4.199 ± 2.158
6.719AsnLeu: 6.719 ± 1.75
0.84AsnMet: 0.84 ± 0.507
3.359AsnAsn: 3.359 ± 1.001
3.639AsnPro: 3.639 ± 0.793
3.08AsnGln: 3.08 ± 1.462
1.96AsnArg: 1.96 ± 0.997
4.759AsnSer: 4.759 ± 1.042
2.52AsnThr: 2.52 ± 0.355
2.24AsnVal: 2.24 ± 1.011
1.68AsnTrp: 1.68 ± 0.383
1.4AsnTyr: 1.4 ± 0.837
0.0AsnXaa: 0.0 ± 0.0
Pro
1.68ProAla: 1.68 ± 0.573
0.56ProCys: 0.56 ± 0.629
1.96ProAsp: 1.96 ± 0.501
2.8ProGlu: 2.8 ± 1.339
1.12ProPhe: 1.12 ± 0.432
0.84ProGly: 0.84 ± 0.724
1.4ProHis: 1.4 ± 0.668
3.919ProIle: 3.919 ± 0.851
2.24ProLys: 2.24 ± 0.469
2.8ProLeu: 2.8 ± 0.977
0.84ProMet: 0.84 ± 0.446
3.919ProAsn: 3.919 ± 0.714
3.639ProPro: 3.639 ± 1.742
0.84ProGln: 0.84 ± 0.725
1.96ProArg: 1.96 ± 1.171
4.199ProSer: 4.199 ± 0.977
2.24ProThr: 2.24 ± 0.887
3.639ProVal: 3.639 ± 0.741
0.84ProTrp: 0.84 ± 0.568
1.68ProTyr: 1.68 ± 0.795
0.0ProXaa: 0.0 ± 0.0
Gln
1.4GlnAla: 1.4 ± 1.598
0.56GlnCys: 0.56 ± 0.335
0.28GlnAsp: 0.28 ± 0.167
2.24GlnGlu: 2.24 ± 1.015
0.84GlnPhe: 0.84 ± 0.361
1.68GlnGly: 1.68 ± 0.701
0.84GlnHis: 0.84 ± 0.502
3.919GlnIle: 3.919 ± 1.321
1.96GlnLys: 1.96 ± 0.862
2.8GlnLeu: 2.8 ± 1.312
0.28GlnMet: 0.28 ± 0.4
1.68GlnAsn: 1.68 ± 0.631
1.12GlnPro: 1.12 ± 0.734
0.56GlnGln: 0.56 ± 0.338
1.12GlnArg: 1.12 ± 0.432
1.68GlnSer: 1.68 ± 1.004
1.12GlnThr: 1.12 ± 0.659
2.24GlnVal: 2.24 ± 1.073
0.28GlnTrp: 0.28 ± 0.167
1.12GlnTyr: 1.12 ± 0.63
0.0GlnXaa: 0.0 ± 0.0
Arg
3.359ArgAla: 3.359 ± 0.733
0.84ArgCys: 0.84 ± 0.349
3.08ArgAsp: 3.08 ± 0.323
4.759ArgGlu: 4.759 ± 0.867
1.96ArgPhe: 1.96 ± 0.795
3.359ArgGly: 3.359 ± 1.09
1.4ArgHis: 1.4 ± 0.837
2.8ArgIle: 2.8 ± 0.936
3.639ArgLys: 3.639 ± 0.952
3.919ArgLeu: 3.919 ± 1.135
0.84ArgMet: 0.84 ± 0.725
3.639ArgAsn: 3.639 ± 1.408
3.08ArgPro: 3.08 ± 1.16
1.12ArgGln: 1.12 ± 0.669
2.8ArgArg: 2.8 ± 0.427
3.359ArgSer: 3.359 ± 0.966
3.359ArgThr: 3.359 ± 0.864
1.68ArgVal: 1.68 ± 0.75
0.0ArgTrp: 0.0 ± 0.0
1.12ArgTyr: 1.12 ± 0.447
0.0ArgXaa: 0.0 ± 0.0
Ser
1.68SerAla: 1.68 ± 0.622
0.56SerCys: 0.56 ± 0.335
4.199SerAsp: 4.199 ± 1.066
3.639SerGlu: 3.639 ± 1.035
2.24SerPhe: 2.24 ± 0.645
3.359SerGly: 3.359 ± 0.547
1.4SerHis: 1.4 ± 0.57
5.599SerIle: 5.599 ± 1.306
5.879SerLys: 5.879 ± 2.126
9.518SerLeu: 9.518 ± 2.507
1.12SerMet: 1.12 ± 0.667
1.96SerAsn: 1.96 ± 1.571
1.12SerPro: 1.12 ± 0.447
2.8SerGln: 2.8 ± 0.482
3.08SerArg: 3.08 ± 1.577
5.319SerSer: 5.319 ± 0.868
3.639SerThr: 3.639 ± 0.864
4.759SerVal: 4.759 ± 2.046
1.68SerTrp: 1.68 ± 0.695
3.08SerTyr: 3.08 ± 1.278
0.0SerXaa: 0.0 ± 0.0
Thr
1.96ThrAla: 1.96 ± 0.66
0.56ThrCys: 0.56 ± 0.338
2.52ThrAsp: 2.52 ± 0.576
2.24ThrGlu: 2.24 ± 0.643
0.84ThrPhe: 0.84 ± 0.408
4.479ThrGly: 4.479 ± 0.795
1.96ThrHis: 1.96 ± 0.585
3.639ThrIle: 3.639 ± 1.419
3.639ThrLys: 3.639 ± 2.11
7.279ThrLeu: 7.279 ± 2.087
1.4ThrMet: 1.4 ± 0.667
3.919ThrAsn: 3.919 ± 0.747
1.12ThrPro: 1.12 ± 0.675
1.96ThrGln: 1.96 ± 0.377
2.24ThrArg: 2.24 ± 0.645
4.759ThrSer: 4.759 ± 0.52
4.479ThrThr: 4.479 ± 0.783
4.199ThrVal: 4.199 ± 0.624
2.24ThrTrp: 2.24 ± 0.806
1.4ThrTyr: 1.4 ± 0.667
0.0ThrXaa: 0.0 ± 0.0
Val
2.24ValAla: 2.24 ± 0.613
1.12ValCys: 1.12 ± 0.417
2.8ValAsp: 2.8 ± 2.004
2.8ValGlu: 2.8 ± 1.013
3.359ValPhe: 3.359 ± 0.831
3.08ValGly: 3.08 ± 1.849
0.84ValHis: 0.84 ± 0.361
5.319ValIle: 5.319 ± 0.836
1.68ValLys: 1.68 ± 1.004
4.479ValLeu: 4.479 ± 1.142
0.84ValMet: 0.84 ± 0.381
2.52ValAsn: 2.52 ± 0.922
1.4ValPro: 1.4 ± 0.427
1.4ValGln: 1.4 ± 1.207
1.96ValArg: 1.96 ± 1.163
4.479ValSer: 4.479 ± 2.028
1.4ValThr: 1.4 ± 0.667
2.24ValVal: 2.24 ± 0.538
0.28ValTrp: 0.28 ± 0.549
1.4ValTyr: 1.4 ± 0.784
0.0ValXaa: 0.0 ± 0.0
Trp
0.28TrpAla: 0.28 ± 0.4
0.56TrpCys: 0.56 ± 0.335
0.56TrpAsp: 0.56 ± 0.335
2.24TrpGlu: 2.24 ± 0.605
1.12TrpPhe: 1.12 ± 0.323
1.12TrpGly: 1.12 ± 0.669
0.84TrpHis: 0.84 ± 0.349
2.24TrpIle: 2.24 ± 1.26
1.68TrpLys: 1.68 ± 0.699
0.84TrpLeu: 0.84 ± 0.502
0.56TrpMet: 0.56 ± 0.335
1.12TrpAsn: 1.12 ± 0.432
0.84TrpPro: 0.84 ± 0.502
0.28TrpGln: 0.28 ± 0.549
0.28TrpArg: 0.28 ± 0.167
1.4TrpSer: 1.4 ± 0.413
0.84TrpThr: 0.84 ± 0.361
0.84TrpVal: 0.84 ± 0.857
0.28TrpTrp: 0.28 ± 0.167
0.84TrpTyr: 0.84 ± 0.408
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.4TyrAla: 1.4 ± 0.57
0.84TyrCys: 0.84 ± 0.349
2.24TyrAsp: 2.24 ± 0.488
3.639TyrGlu: 3.639 ± 1.374
1.96TyrPhe: 1.96 ± 0.57
1.96TyrGly: 1.96 ± 0.554
0.56TyrHis: 0.56 ± 0.342
2.52TyrIle: 2.52 ± 1.159
4.199TyrLys: 4.199 ± 0.91
5.039TyrLeu: 5.039 ± 1.836
1.12TyrMet: 1.12 ± 0.447
1.12TyrAsn: 1.12 ± 0.447
0.84TyrPro: 0.84 ± 0.507
0.56TyrGln: 0.56 ± 0.693
2.52TyrArg: 2.52 ± 0.713
1.68TyrSer: 1.68 ± 0.722
2.24TyrThr: 2.24 ± 0.655
1.68TyrVal: 1.68 ± 1.033
0.56TyrTrp: 0.56 ± 0.338
0.56TyrTyr: 0.56 ± 0.335
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski