Amino acid dipepetide frequency for Acinetobacter phage vB_AbaP_PD-6A3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.336AlaAla: 7.336 ± 1.072
0.468AlaCys: 0.468 ± 0.228
5.463AlaAsp: 5.463 ± 0.775
5.307AlaGlu: 5.307 ± 0.557
2.029AlaPhe: 2.029 ± 0.316
6.867AlaGly: 6.867 ± 0.457
1.873AlaHis: 1.873 ± 0.455
5.385AlaIle: 5.385 ± 0.823
5.463AlaLys: 5.463 ± 0.57
8.74AlaLeu: 8.74 ± 0.748
2.809AlaMet: 2.809 ± 0.482
3.668AlaAsn: 3.668 ± 0.384
2.029AlaPro: 2.029 ± 0.488
4.448AlaGln: 4.448 ± 0.656
2.263AlaArg: 2.263 ± 0.422
4.058AlaSer: 4.058 ± 0.601
4.76AlaThr: 4.76 ± 0.603
5.073AlaVal: 5.073 ± 0.664
0.858AlaTrp: 0.858 ± 0.216
3.044AlaTyr: 3.044 ± 0.438
0.0AlaXaa: 0.0 ± 0.0
Cys
0.936CysAla: 0.936 ± 0.326
0.234CysCys: 0.234 ± 0.116
1.093CysAsp: 1.093 ± 0.346
0.234CysGlu: 0.234 ± 0.15
0.546CysPhe: 0.546 ± 0.184
1.093CysGly: 1.093 ± 0.297
0.468CysHis: 0.468 ± 0.202
0.78CysIle: 0.78 ± 0.333
0.156CysLys: 0.156 ± 0.116
1.171CysLeu: 1.171 ± 0.32
0.0CysMet: 0.0 ± 0.0
0.312CysAsn: 0.312 ± 0.161
0.312CysPro: 0.312 ± 0.152
0.156CysGln: 0.156 ± 0.128
0.312CysArg: 0.312 ± 0.162
0.624CysSer: 0.624 ± 0.215
0.468CysThr: 0.468 ± 0.196
0.858CysVal: 0.858 ± 0.332
0.234CysTrp: 0.234 ± 0.12
0.624CysTyr: 0.624 ± 0.222
0.0CysXaa: 0.0 ± 0.0
Asp
5.073AspAla: 5.073 ± 0.692
1.093AspCys: 1.093 ± 0.293
3.746AspAsp: 3.746 ± 0.612
3.668AspGlu: 3.668 ± 0.423
2.107AspPhe: 2.107 ± 0.406
4.058AspGly: 4.058 ± 0.668
1.561AspHis: 1.561 ± 0.402
4.682AspIle: 4.682 ± 0.569
4.995AspLys: 4.995 ± 0.615
4.682AspLeu: 4.682 ± 0.679
1.561AspMet: 1.561 ± 0.407
3.278AspAsn: 3.278 ± 0.481
1.873AspPro: 1.873 ± 0.311
2.263AspGln: 2.263 ± 0.356
3.122AspArg: 3.122 ± 0.568
3.668AspSer: 3.668 ± 0.577
3.98AspThr: 3.98 ± 0.65
4.058AspVal: 4.058 ± 0.545
1.717AspTrp: 1.717 ± 0.411
2.731AspTyr: 2.731 ± 0.585
0.0AspXaa: 0.0 ± 0.0
Glu
5.307GluAla: 5.307 ± 0.804
0.312GluCys: 0.312 ± 0.156
4.214GluAsp: 4.214 ± 0.587
3.902GluGlu: 3.902 ± 0.589
2.029GluPhe: 2.029 ± 0.403
3.122GluGly: 3.122 ± 0.527
1.327GluHis: 1.327 ± 0.264
3.2GluIle: 3.2 ± 0.684
2.185GluLys: 2.185 ± 0.646
6.633GluLeu: 6.633 ± 0.593
1.405GluMet: 1.405 ± 0.335
2.419GluAsn: 2.419 ± 0.434
2.731GluPro: 2.731 ± 0.383
3.356GluGln: 3.356 ± 0.483
2.731GluArg: 2.731 ± 0.512
2.341GluSer: 2.341 ± 0.465
2.107GluThr: 2.107 ± 0.416
4.214GluVal: 4.214 ± 0.526
1.249GluTrp: 1.249 ± 0.267
3.668GluTyr: 3.668 ± 0.453
0.0GluXaa: 0.0 ± 0.0
Phe
2.887PheAla: 2.887 ± 0.511
0.468PheCys: 0.468 ± 0.208
2.185PheAsp: 2.185 ± 0.39
2.575PheGlu: 2.575 ± 0.382
1.093PhePhe: 1.093 ± 0.246
2.966PheGly: 2.966 ± 0.529
0.546PheHis: 0.546 ± 0.189
1.873PheIle: 1.873 ± 0.432
2.263PheLys: 2.263 ± 0.35
2.731PheLeu: 2.731 ± 0.446
0.78PheMet: 0.78 ± 0.2
2.107PheAsn: 2.107 ± 0.48
1.483PhePro: 1.483 ± 0.36
1.561PheGln: 1.561 ± 0.358
1.015PheArg: 1.015 ± 0.308
2.419PheSer: 2.419 ± 0.331
1.951PheThr: 1.951 ± 0.367
1.951PheVal: 1.951 ± 0.436
0.234PheTrp: 0.234 ± 0.111
0.78PheTyr: 0.78 ± 0.258
0.0PheXaa: 0.0 ± 0.0
Gly
5.619GlyAla: 5.619 ± 0.752
0.546GlyCys: 0.546 ± 0.212
3.746GlyAsp: 3.746 ± 0.469
3.278GlyGlu: 3.278 ± 0.572
2.029GlyPhe: 2.029 ± 0.388
5.775GlyGly: 5.775 ± 1.132
0.936GlyHis: 0.936 ± 0.3
4.604GlyIle: 4.604 ± 0.469
6.633GlyLys: 6.633 ± 0.806
5.463GlyLeu: 5.463 ± 0.728
2.809GlyMet: 2.809 ± 0.683
3.59GlyAsn: 3.59 ± 0.624
1.015GlyPro: 1.015 ± 0.325
3.122GlyGln: 3.122 ± 0.554
3.668GlyArg: 3.668 ± 0.436
4.838GlySer: 4.838 ± 0.954
6.477GlyThr: 6.477 ± 0.975
5.229GlyVal: 5.229 ± 0.746
0.936GlyTrp: 0.936 ± 0.252
2.966GlyTyr: 2.966 ± 0.514
0.0GlyXaa: 0.0 ± 0.0
His
1.405HisAla: 1.405 ± 0.403
0.312HisCys: 0.312 ± 0.145
1.639HisAsp: 1.639 ± 0.423
1.015HisGlu: 1.015 ± 0.294
1.249HisPhe: 1.249 ± 0.305
1.795HisGly: 1.795 ± 0.396
0.234HisHis: 0.234 ± 0.119
1.327HisIle: 1.327 ± 0.284
1.639HisLys: 1.639 ± 0.493
1.639HisLeu: 1.639 ± 0.301
0.312HisMet: 0.312 ± 0.145
1.171HisAsn: 1.171 ± 0.291
1.015HisPro: 1.015 ± 0.205
1.015HisGln: 1.015 ± 0.254
0.702HisArg: 0.702 ± 0.21
0.858HisSer: 0.858 ± 0.248
0.156HisThr: 0.156 ± 0.099
1.639HisVal: 1.639 ± 0.26
0.702HisTrp: 0.702 ± 0.213
0.936HisTyr: 0.936 ± 0.329
0.0HisXaa: 0.0 ± 0.0
Ile
5.151IleAla: 5.151 ± 0.508
0.39IleCys: 0.39 ± 0.166
4.995IleAsp: 4.995 ± 0.608
3.044IleGlu: 3.044 ± 0.495
1.327IlePhe: 1.327 ± 0.364
3.356IleGly: 3.356 ± 0.478
1.405IleHis: 1.405 ± 0.34
3.434IleIle: 3.434 ± 0.45
4.682IleLys: 4.682 ± 0.613
3.59IleLeu: 3.59 ± 0.527
1.561IleMet: 1.561 ± 0.365
3.122IleAsn: 3.122 ± 0.341
2.497IlePro: 2.497 ± 0.512
2.653IleGln: 2.653 ± 0.411
3.122IleArg: 3.122 ± 0.618
2.966IleSer: 2.966 ± 0.431
3.512IleThr: 3.512 ± 0.524
2.497IleVal: 2.497 ± 0.343
0.624IleTrp: 0.624 ± 0.226
2.185IleTyr: 2.185 ± 0.455
0.0IleXaa: 0.0 ± 0.0
Lys
6.477LysAla: 6.477 ± 0.738
0.624LysCys: 0.624 ± 0.255
4.136LysAsp: 4.136 ± 0.565
5.385LysGlu: 5.385 ± 0.745
2.575LysPhe: 2.575 ± 0.394
5.931LysGly: 5.931 ± 0.578
2.107LysHis: 2.107 ± 0.481
2.497LysIle: 2.497 ± 0.418
3.044LysLys: 3.044 ± 0.611
5.463LysLeu: 5.463 ± 0.488
1.483LysMet: 1.483 ± 0.264
2.575LysAsn: 2.575 ± 0.46
2.966LysPro: 2.966 ± 0.668
2.731LysGln: 2.731 ± 0.496
3.746LysArg: 3.746 ± 0.618
4.058LysSer: 4.058 ± 0.522
4.214LysThr: 4.214 ± 0.673
5.307LysVal: 5.307 ± 0.857
0.936LysTrp: 0.936 ± 0.254
2.575LysTyr: 2.575 ± 0.454
0.0LysXaa: 0.0 ± 0.0
Leu
7.18LeuAla: 7.18 ± 0.675
1.171LeuCys: 1.171 ± 0.258
6.321LeuAsp: 6.321 ± 0.507
4.916LeuGlu: 4.916 ± 0.789
2.731LeuPhe: 2.731 ± 0.491
5.229LeuGly: 5.229 ± 0.584
1.483LeuHis: 1.483 ± 0.419
4.136LeuIle: 4.136 ± 0.598
6.243LeuLys: 6.243 ± 0.664
7.726LeuLeu: 7.726 ± 1.077
1.483LeuMet: 1.483 ± 0.301
4.526LeuAsn: 4.526 ± 0.536
2.966LeuPro: 2.966 ± 0.556
3.668LeuGln: 3.668 ± 0.563
4.37LeuArg: 4.37 ± 0.548
5.307LeuSer: 5.307 ± 0.479
5.151LeuThr: 5.151 ± 0.723
5.619LeuVal: 5.619 ± 0.48
0.702LeuTrp: 0.702 ± 0.197
2.887LeuTyr: 2.887 ± 0.394
0.0LeuXaa: 0.0 ± 0.0
Met
2.419MetAla: 2.419 ± 0.55
0.312MetCys: 0.312 ± 0.156
2.107MetAsp: 2.107 ± 0.441
1.093MetGlu: 1.093 ± 0.218
1.015MetPhe: 1.015 ± 0.24
1.327MetGly: 1.327 ± 0.23
0.624MetHis: 0.624 ± 0.178
1.483MetIle: 1.483 ± 0.415
1.795MetLys: 1.795 ± 0.32
1.873MetLeu: 1.873 ± 0.347
0.468MetMet: 0.468 ± 0.176
1.405MetAsn: 1.405 ± 0.326
0.858MetPro: 0.858 ± 0.323
1.561MetGln: 1.561 ± 0.298
1.795MetArg: 1.795 ± 0.325
2.107MetSer: 2.107 ± 0.359
1.951MetThr: 1.951 ± 0.376
0.936MetVal: 0.936 ± 0.23
0.156MetTrp: 0.156 ± 0.125
1.483MetTyr: 1.483 ± 0.329
0.0MetXaa: 0.0 ± 0.0
Asn
3.902AsnAla: 3.902 ± 0.595
0.39AsnCys: 0.39 ± 0.159
1.795AsnAsp: 1.795 ± 0.38
2.107AsnGlu: 2.107 ± 0.362
1.795AsnPhe: 1.795 ± 0.405
5.073AsnGly: 5.073 ± 0.649
0.936AsnHis: 0.936 ± 0.281
2.809AsnIle: 2.809 ± 0.398
3.356AsnLys: 3.356 ± 0.368
3.668AsnLeu: 3.668 ± 0.489
1.405AsnMet: 1.405 ± 0.237
1.873AsnAsn: 1.873 ± 0.365
3.2AsnPro: 3.2 ± 0.483
1.951AsnGln: 1.951 ± 0.427
2.497AsnArg: 2.497 ± 0.527
2.731AsnSer: 2.731 ± 0.439
3.278AsnThr: 3.278 ± 0.463
2.966AsnVal: 2.966 ± 0.388
0.624AsnTrp: 0.624 ± 0.217
2.653AsnTyr: 2.653 ± 0.313
0.0AsnXaa: 0.0 ± 0.0
Pro
2.887ProAla: 2.887 ± 0.603
0.156ProCys: 0.156 ± 0.11
2.497ProAsp: 2.497 ± 0.371
3.278ProGlu: 3.278 ± 0.406
1.171ProPhe: 1.171 ± 0.276
0.0ProGly: 0.0 ± 0.0
0.624ProHis: 0.624 ± 0.244
2.575ProIle: 2.575 ± 0.495
2.731ProLys: 2.731 ± 0.454
2.575ProLeu: 2.575 ± 0.412
1.171ProMet: 1.171 ± 0.381
2.341ProAsn: 2.341 ± 0.467
0.702ProPro: 0.702 ± 0.185
1.717ProGln: 1.717 ± 0.452
1.327ProArg: 1.327 ± 0.311
1.873ProSer: 1.873 ± 0.478
3.044ProThr: 3.044 ± 0.39
3.122ProVal: 3.122 ± 0.542
0.078ProTrp: 0.078 ± 0.065
2.107ProTyr: 2.107 ± 0.381
0.0ProXaa: 0.0 ± 0.0
Gln
3.668GlnAla: 3.668 ± 0.594
0.39GlnCys: 0.39 ± 0.227
2.185GlnAsp: 2.185 ± 0.389
2.887GlnGlu: 2.887 ± 0.531
2.107GlnPhe: 2.107 ± 0.381
3.824GlnGly: 3.824 ± 0.765
1.717GlnHis: 1.717 ± 0.375
2.341GlnIle: 2.341 ± 0.407
2.731GlnLys: 2.731 ± 0.452
4.76GlnLeu: 4.76 ± 0.71
1.093GlnMet: 1.093 ± 0.322
1.483GlnAsn: 1.483 ± 0.325
1.405GlnPro: 1.405 ± 0.274
2.575GlnGln: 2.575 ± 0.476
2.419GlnArg: 2.419 ± 0.373
1.951GlnSer: 1.951 ± 0.334
2.263GlnThr: 2.263 ± 0.425
4.214GlnVal: 4.214 ± 0.594
0.468GlnTrp: 0.468 ± 0.176
2.575GlnTyr: 2.575 ± 0.371
0.0GlnXaa: 0.0 ± 0.0
Arg
3.512ArgAla: 3.512 ± 0.474
0.702ArgCys: 0.702 ± 0.227
2.107ArgAsp: 2.107 ± 0.407
3.044ArgGlu: 3.044 ± 0.613
1.873ArgPhe: 1.873 ± 0.368
3.356ArgGly: 3.356 ± 0.494
0.702ArgHis: 0.702 ± 0.211
2.887ArgIle: 2.887 ± 0.392
3.2ArgLys: 3.2 ± 0.633
4.526ArgLeu: 4.526 ± 0.688
1.795ArgMet: 1.795 ± 0.366
3.356ArgAsn: 3.356 ± 0.617
1.171ArgPro: 1.171 ± 0.322
2.029ArgGln: 2.029 ± 0.414
2.966ArgArg: 2.966 ± 0.588
2.653ArgSer: 2.653 ± 0.417
2.185ArgThr: 2.185 ± 0.411
3.434ArgVal: 3.434 ± 0.458
0.468ArgTrp: 0.468 ± 0.166
1.951ArgTyr: 1.951 ± 0.334
0.0ArgXaa: 0.0 ± 0.0
Ser
4.448SerAla: 4.448 ± 0.617
0.624SerCys: 0.624 ± 0.207
3.98SerAsp: 3.98 ± 0.62
2.575SerGlu: 2.575 ± 0.57
2.263SerPhe: 2.263 ± 0.385
4.37SerGly: 4.37 ± 0.605
1.093SerHis: 1.093 ± 0.306
3.356SerIle: 3.356 ± 0.589
5.151SerLys: 5.151 ± 0.584
3.434SerLeu: 3.434 ± 0.391
1.405SerMet: 1.405 ± 0.365
2.497SerAsn: 2.497 ± 0.434
1.639SerPro: 1.639 ± 0.361
2.029SerGln: 2.029 ± 0.456
2.575SerArg: 2.575 ± 0.512
3.434SerSer: 3.434 ± 0.672
5.307SerThr: 5.307 ± 1.026
2.653SerVal: 2.653 ± 0.445
0.702SerTrp: 0.702 ± 0.312
2.575SerTyr: 2.575 ± 0.39
0.0SerXaa: 0.0 ± 0.0
Thr
4.838ThrAla: 4.838 ± 0.678
0.468ThrCys: 0.468 ± 0.164
3.824ThrAsp: 3.824 ± 0.587
3.2ThrGlu: 3.2 ± 0.45
1.717ThrPhe: 1.717 ± 0.305
6.477ThrGly: 6.477 ± 0.564
0.78ThrHis: 0.78 ± 0.269
3.278ThrIle: 3.278 ± 0.412
3.668ThrLys: 3.668 ± 0.438
4.995ThrLeu: 4.995 ± 0.567
1.717ThrMet: 1.717 ± 0.393
1.951ThrAsn: 1.951 ± 0.439
2.809ThrPro: 2.809 ± 0.492
3.98ThrGln: 3.98 ± 0.755
2.809ThrArg: 2.809 ± 0.438
2.653ThrSer: 2.653 ± 0.464
4.76ThrThr: 4.76 ± 0.585
5.151ThrVal: 5.151 ± 0.746
0.858ThrTrp: 0.858 ± 0.229
2.575ThrTyr: 2.575 ± 0.322
0.0ThrXaa: 0.0 ± 0.0
Val
5.619ValAla: 5.619 ± 0.421
0.702ValCys: 0.702 ± 0.235
3.98ValAsp: 3.98 ± 0.658
3.98ValGlu: 3.98 ± 0.509
2.263ValPhe: 2.263 ± 0.473
5.073ValGly: 5.073 ± 0.597
1.405ValHis: 1.405 ± 0.337
2.966ValIle: 2.966 ± 0.524
4.682ValLys: 4.682 ± 0.673
4.448ValLeu: 4.448 ± 0.583
1.717ValMet: 1.717 ± 0.306
3.98ValAsn: 3.98 ± 0.53
3.434ValPro: 3.434 ± 0.387
3.512ValGln: 3.512 ± 0.555
3.668ValArg: 3.668 ± 0.533
4.292ValSer: 4.292 ± 0.461
3.98ValThr: 3.98 ± 0.667
4.995ValVal: 4.995 ± 0.637
0.546ValTrp: 0.546 ± 0.228
2.497ValTyr: 2.497 ± 0.431
0.0ValXaa: 0.0 ± 0.0
Trp
0.624TrpAla: 0.624 ± 0.209
0.546TrpCys: 0.546 ± 0.217
0.78TrpAsp: 0.78 ± 0.281
0.702TrpGlu: 0.702 ± 0.197
0.702TrpPhe: 0.702 ± 0.275
0.78TrpGly: 0.78 ± 0.201
0.156TrpHis: 0.156 ± 0.102
0.546TrpIle: 0.546 ± 0.199
1.171TrpLys: 1.171 ± 0.247
1.483TrpLeu: 1.483 ± 0.362
0.312TrpMet: 0.312 ± 0.126
0.858TrpAsn: 0.858 ± 0.268
0.0TrpPro: 0.0 ± 0.0
0.312TrpGln: 0.312 ± 0.14
0.546TrpArg: 0.546 ± 0.169
0.546TrpSer: 0.546 ± 0.183
0.78TrpThr: 0.78 ± 0.306
0.936TrpVal: 0.936 ± 0.277
0.234TrpTrp: 0.234 ± 0.116
0.624TrpTyr: 0.624 ± 0.217
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.653TyrAla: 2.653 ± 0.491
0.702TyrCys: 0.702 ± 0.266
3.122TyrAsp: 3.122 ± 0.437
2.341TyrGlu: 2.341 ± 0.57
1.249TyrPhe: 1.249 ± 0.261
2.809TyrGly: 2.809 ± 0.481
0.78TyrHis: 0.78 ± 0.274
1.951TyrIle: 1.951 ± 0.463
3.044TyrLys: 3.044 ± 0.523
4.214TyrLeu: 4.214 ± 0.584
1.405TyrMet: 1.405 ± 0.278
2.497TyrAsn: 2.497 ± 0.526
1.873TyrPro: 1.873 ± 0.32
2.419TyrGln: 2.419 ± 0.497
2.263TyrArg: 2.263 ± 0.38
2.731TyrSer: 2.731 ± 0.402
2.185TyrThr: 2.185 ± 0.367
2.887TyrVal: 2.887 ± 0.61
0.312TyrTrp: 0.312 ± 0.143
1.249TyrTyr: 1.249 ± 0.373
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 48 proteins (12815 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski