Amino acid dipepetide frequency for Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.904AlaAla: 13.904 ± 0.123	0.889AlaCys: 0.889 ± 0.019	5.675AlaAsp: 5.675 ± 0.054	6.106AlaGlu: 6.106 ± 0.06	3.318AlaPhe: 3.318 ± 0.039	7.509AlaGly: 7.509 ± 0.051	2.098AlaHis: 2.098 ± 0.025	4.147AlaIle: 4.147 ± 0.037	5.208AlaLys: 5.208 ± 0.059	8.723AlaLeu: 8.723 ± 0.063	2.069AlaMet: 2.069 ± 0.025	3.424AlaAsn: 3.424 ± 0.033	5.988AlaPro: 5.988 ± 0.066	4.293AlaGln: 4.293 ± 0.05	6.11AlaArg: 6.11 ± 0.054	10.852AlaSer: 10.852 ± 0.081	6.141AlaThr: 6.141 ± 0.047	5.885AlaVal: 5.885 ± 0.048	1.114AlaTrp: 1.114 ± 0.021	2.191AlaTyr: 2.191 ± 0.028	0.0AlaXaa: 0.0 ± 0.0
Cys	0.789CysAla: 0.789 ± 0.018	0.152CysCys: 0.152 ± 0.007	0.494CysAsp: 0.494 ± 0.014	0.421CysGlu: 0.421 ± 0.012	0.425CysPhe: 0.425 ± 0.011	0.707CysGly: 0.707 ± 0.015	0.229CysHis: 0.229 ± 0.009	0.523CysIle: 0.523 ± 0.013	0.413CysLys: 0.413 ± 0.012	0.947CysLeu: 0.947 ± 0.021	0.19CysMet: 0.19 ± 0.007	0.308CysAsn: 0.308 ± 0.011	0.474CysPro: 0.474 ± 0.013	0.325CysGln: 0.325 ± 0.011	0.554CysArg: 0.554 ± 0.012	0.703CysSer: 0.703 ± 0.016	0.54CysThr: 0.54 ± 0.013	0.61CysVal: 0.61 ± 0.013	0.133CysTrp: 0.133 ± 0.006	0.26CysTyr: 0.26 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.614AspAla: 6.614 ± 0.05	0.467AspCys: 0.467 ± 0.012	5.296AspAsp: 5.296 ± 0.074	5.182AspGlu: 5.182 ± 0.063	2.0AspPhe: 2.0 ± 0.03	4.369AspGly: 4.369 ± 0.043	1.196AspHis: 1.196 ± 0.023	2.241AspIle: 2.241 ± 0.029	2.47AspLys: 2.47 ± 0.032	5.276AspLeu: 5.276 ± 0.045	1.142AspMet: 1.142 ± 0.019	1.564AspAsn: 1.564 ± 0.024	3.434AspPro: 3.434 ± 0.036	2.004AspGln: 2.004 ± 0.027	3.25AspArg: 3.25 ± 0.039	4.275AspSer: 4.275 ± 0.041	2.838AspThr: 2.838 ± 0.029	3.847AspVal: 3.847 ± 0.037	0.824AspTrp: 0.824 ± 0.015	1.363AspTyr: 1.363 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	6.632GluAla: 6.632 ± 0.066	0.464GluCys: 0.464 ± 0.014	4.349GluAsp: 4.349 ± 0.051	5.595GluGlu: 5.595 ± 0.071	1.606GluPhe: 1.606 ± 0.026	3.936GluGly: 3.936 ± 0.036	1.298GluHis: 1.298 ± 0.024	2.41GluIle: 2.41 ± 0.029	3.203GluLys: 3.203 ± 0.043	5.36GluLeu: 5.36 ± 0.057	1.407GluMet: 1.407 ± 0.022	1.582GluAsn: 1.582 ± 0.025	2.491GluPro: 2.491 ± 0.033	2.713GluGln: 2.713 ± 0.039	4.189GluArg: 4.189 ± 0.04	4.088GluSer: 4.088 ± 0.042	3.088GluThr: 3.088 ± 0.033	3.557GluVal: 3.557 ± 0.035	0.767GluTrp: 0.767 ± 0.016	1.315GluTyr: 1.315 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.392PheAla: 3.392 ± 0.034	0.424PheCys: 0.424 ± 0.012	2.326PheAsp: 2.326 ± 0.026	1.951PheGlu: 1.951 ± 0.028	1.417PhePhe: 1.417 ± 0.025	2.921PheGly: 2.921 ± 0.043	0.78PheHis: 0.78 ± 0.016	1.349PheIle: 1.349 ± 0.019	1.32PheLys: 1.32 ± 0.019	3.008PheLeu: 3.008 ± 0.036	0.653PheMet: 0.653 ± 0.014	1.227PheAsn: 1.227 ± 0.02	1.532PhePro: 1.532 ± 0.024	1.118PheGln: 1.118 ± 0.018	1.781PheArg: 1.781 ± 0.023	2.753PheSer: 2.753 ± 0.034	1.833PheThr: 1.833 ± 0.027	2.369PheVal: 2.369 ± 0.026	0.497PheTrp: 0.497 ± 0.012	0.955PheTyr: 0.955 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	7.031GlyAla: 7.031 ± 0.063	0.677GlyCys: 0.677 ± 0.016	3.667GlyAsp: 3.667 ± 0.038	3.898GlyGlu: 3.898 ± 0.038	2.647GlyPhe: 2.647 ± 0.038	6.822GlyGly: 6.822 ± 0.083	1.577GlyHis: 1.577 ± 0.028	3.007GlyIle: 3.007 ± 0.034	3.967GlyLys: 3.967 ± 0.044	6.215GlyLeu: 6.215 ± 0.05	1.654GlyMet: 1.654 ± 0.022	2.31GlyAsn: 2.31 ± 0.033	3.385GlyPro: 3.385 ± 0.043	2.673GlyGln: 2.673 ± 0.034	4.329GlyArg: 4.329 ± 0.044	6.81GlySer: 6.81 ± 0.062	3.963GlyThr: 3.963 ± 0.043	4.317GlyVal: 4.317 ± 0.039	1.103GlyTrp: 1.103 ± 0.019	1.881GlyTyr: 1.881 ± 0.028	0.001GlyXaa: 0.001 ± 0.0
His	2.175HisAla: 2.175 ± 0.028	0.239HisCys: 0.239 ± 0.009	1.276HisAsp: 1.276 ± 0.022	1.159HisGlu: 1.159 ± 0.021	0.869HisPhe: 0.869 ± 0.017	1.545HisGly: 1.545 ± 0.025	0.79HisHis: 0.79 ± 0.022	1.004HisIle: 1.004 ± 0.018	0.836HisLys: 0.836 ± 0.018	2.315HisLeu: 2.315 ± 0.029	0.418HisMet: 0.418 ± 0.011	0.675HisAsn: 0.675 ± 0.014	1.604HisPro: 1.604 ± 0.028	0.925HisGln: 0.925 ± 0.017	1.476HisArg: 1.476 ± 0.023	1.748HisSer: 1.748 ± 0.026	1.199HisThr: 1.199 ± 0.02	1.357HisVal: 1.357 ± 0.021	0.276HisTrp: 0.276 ± 0.008	0.583HisTyr: 0.583 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.152IleAla: 4.152 ± 0.036	0.528IleCys: 0.528 ± 0.013	2.746IleAsp: 2.746 ± 0.031	2.599IleGlu: 2.599 ± 0.032	1.561IlePhe: 1.561 ± 0.024	2.806IleGly: 2.806 ± 0.033	0.966IleHis: 0.966 ± 0.018	1.747IleIle: 1.747 ± 0.028	2.004IleLys: 2.004 ± 0.028	3.72IleLeu: 3.72 ± 0.039	0.754IleMet: 0.754 ± 0.014	1.478IleAsn: 1.478 ± 0.023	2.364IlePro: 2.364 ± 0.026	1.523IleGln: 1.523 ± 0.022	2.53IleArg: 2.53 ± 0.03	3.268IleSer: 3.268 ± 0.035	2.254IleThr: 2.254 ± 0.03	2.872IleVal: 2.872 ± 0.031	0.528IleTrp: 0.528 ± 0.012	1.033IleTyr: 1.033 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	5.087LysAla: 5.087 ± 0.052	0.37LysCys: 0.37 ± 0.011	2.826LysAsp: 2.826 ± 0.039	3.187LysGlu: 3.187 ± 0.04	1.196LysPhe: 1.196 ± 0.021	3.295LysGly: 3.295 ± 0.038	1.059LysHis: 1.059 ± 0.021	1.907LysIle: 1.907 ± 0.025	3.366LysLys: 3.366 ± 0.05	4.206LysLeu: 4.206 ± 0.035	1.028LysMet: 1.028 ± 0.02	1.418LysAsn: 1.418 ± 0.023	2.578LysPro: 2.578 ± 0.029	2.12LysGln: 2.12 ± 0.03	3.56LysArg: 3.56 ± 0.039	3.449LysSer: 3.449 ± 0.042	2.699LysThr: 2.699 ± 0.031	2.999LysVal: 2.999 ± 0.033	0.559LysTrp: 0.559 ± 0.012	1.084LysTyr: 1.084 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	9.053LeuAla: 9.053 ± 0.062	0.985LeuCys: 0.985 ± 0.017	5.559LeuAsp: 5.559 ± 0.048	5.298LeuGlu: 5.298 ± 0.054	3.125LeuPhe: 3.125 ± 0.034	6.016LeuGly: 6.016 ± 0.05	2.103LeuHis: 2.103 ± 0.025	3.591LeuIle: 3.591 ± 0.036	3.927LeuLys: 3.927 ± 0.035	8.439LeuLeu: 8.439 ± 0.068	1.688LeuMet: 1.688 ± 0.023	2.911LeuAsn: 2.911 ± 0.033	5.544LeuPro: 5.544 ± 0.046	3.709LeuGln: 3.709 ± 0.043	5.848LeuArg: 5.848 ± 0.051	7.634LeuSer: 7.634 ± 0.055	4.946LeuThr: 4.946 ± 0.049	5.606LeuVal: 5.606 ± 0.046	0.987LeuTrp: 0.987 ± 0.02	2.025LeuTyr: 2.025 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.1MetAla: 2.1 ± 0.031	0.185MetCys: 0.185 ± 0.008	1.238MetAsp: 1.238 ± 0.021	1.103MetGlu: 1.103 ± 0.021	0.595MetPhe: 0.595 ± 0.014	1.432MetGly: 1.432 ± 0.024	0.451MetHis: 0.451 ± 0.012	0.828MetIle: 0.828 ± 0.02	0.772MetLys: 0.772 ± 0.016	1.931MetLeu: 1.931 ± 0.023	0.529MetMet: 0.529 ± 0.013	0.604MetAsn: 0.604 ± 0.014	1.248MetPro: 1.248 ± 0.02	0.923MetGln: 0.923 ± 0.02	1.266MetArg: 1.266 ± 0.02	1.894MetSer: 1.894 ± 0.025	1.185MetThr: 1.185 ± 0.022	1.223MetVal: 1.223 ± 0.02	0.231MetTrp: 0.231 ± 0.008	0.437MetTyr: 0.437 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.616AsnAla: 3.616 ± 0.037	0.294AsnCys: 0.294 ± 0.01	1.845AsnAsp: 1.845 ± 0.027	1.72AsnGlu: 1.72 ± 0.023	1.135AsnPhe: 1.135 ± 0.02	3.065AsnGly: 3.065 ± 0.038	0.677AsnHis: 0.677 ± 0.016	1.389AsnIle: 1.389 ± 0.022	1.409AsnLys: 1.409 ± 0.021	2.866AsnLeu: 2.866 ± 0.034	0.655AsnMet: 0.655 ± 0.014	1.156AsnAsn: 1.156 ± 0.021	2.025AsnPro: 2.025 ± 0.03	1.106AsnGln: 1.106 ± 0.023	1.785AsnArg: 1.785 ± 0.026	2.408AsnSer: 2.408 ± 0.029	1.818AsnThr: 1.818 ± 0.024	2.21AsnVal: 2.21 ± 0.029	0.408AsnTrp: 0.408 ± 0.012	0.794AsnTyr: 0.794 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.386ProAla: 6.386 ± 0.066	0.365ProCys: 0.365 ± 0.012	2.883ProAsp: 2.883 ± 0.033	3.125ProGlu: 3.125 ± 0.029	1.9ProPhe: 1.9 ± 0.03	3.801ProGly: 3.801 ± 0.041	1.264ProHis: 1.264 ± 0.022	2.266ProIle: 2.266 ± 0.027	2.462ProLys: 2.462 ± 0.032	4.626ProLeu: 4.626 ± 0.046	0.989ProMet: 0.989 ± 0.021	1.9ProAsn: 1.9 ± 0.029	4.494ProPro: 4.494 ± 0.076	2.179ProGln: 2.179 ± 0.036	3.123ProArg: 3.123 ± 0.037	6.805ProSer: 6.805 ± 0.068	4.158ProThr: 4.158 ± 0.042	3.288ProVal: 3.288 ± 0.036	0.57ProTrp: 0.57 ± 0.012	1.299ProTyr: 1.299 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	4.305GlnAla: 4.305 ± 0.053	0.317GlnCys: 0.317 ± 0.011	2.208GlnAsp: 2.208 ± 0.025	2.225GlnGlu: 2.225 ± 0.029	1.067GlnPhe: 1.067 ± 0.02	2.556GlnGly: 2.556 ± 0.032	1.1GlnHis: 1.1 ± 0.023	1.722GlnIle: 1.722 ± 0.026	1.766GlnLys: 1.766 ± 0.024	3.811GlnLeu: 3.811 ± 0.044	0.941GlnMet: 0.941 ± 0.02	1.272GlnAsn: 1.272 ± 0.02	2.538GlnPro: 2.538 ± 0.037	3.061GlnGln: 3.061 ± 0.082	2.857GlnArg: 2.857 ± 0.035	3.186GlnSer: 3.186 ± 0.036	2.217GlnThr: 2.217 ± 0.027	2.216GlnVal: 2.216 ± 0.032	0.455GlnTrp: 0.455 ± 0.012	0.945GlnTyr: 0.945 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	5.707ArgAla: 5.707 ± 0.046	0.572ArgCys: 0.572 ± 0.015	3.341ArgAsp: 3.341 ± 0.04	3.722ArgGlu: 3.722 ± 0.039	2.215ArgPhe: 2.215 ± 0.031	3.907ArgGly: 3.907 ± 0.042	1.391ArgHis: 1.391 ± 0.026	2.828ArgIle: 2.828 ± 0.034	3.649ArgLys: 3.649 ± 0.037	5.524ArgLeu: 5.524 ± 0.048	1.351ArgMet: 1.351 ± 0.02	2.108ArgAsn: 2.108 ± 0.025	3.42ArgPro: 3.42 ± 0.041	2.618ArgGln: 2.618 ± 0.034	5.142ArgArg: 5.142 ± 0.056	5.604ArgSer: 5.604 ± 0.048	3.502ArgThr: 3.502 ± 0.035	3.335ArgVal: 3.335 ± 0.034	0.78ArgTrp: 0.78 ± 0.015	1.542ArgTyr: 1.542 ± 0.022	0.001ArgXaa: 0.001 ± 0.0
Ser	9.535SerAla: 9.535 ± 0.071	0.633SerCys: 0.633 ± 0.015	4.8SerAsp: 4.8 ± 0.044	4.032SerGlu: 4.032 ± 0.044	2.933SerPhe: 2.933 ± 0.032	6.291SerGly: 6.291 ± 0.05	1.996SerHis: 1.996 ± 0.03	3.827SerIle: 3.827 ± 0.037	4.108SerLys: 4.108 ± 0.043	7.518SerLeu: 7.518 ± 0.058	1.74SerMet: 1.74 ± 0.028	3.246SerAsn: 3.246 ± 0.039	5.308SerPro: 5.308 ± 0.061	3.468SerGln: 3.468 ± 0.039	5.358SerArg: 5.358 ± 0.052	12.143SerSer: 12.143 ± 0.113	6.632SerThr: 6.632 ± 0.059	4.842SerVal: 4.842 ± 0.039	0.897SerTrp: 0.897 ± 0.019	1.927SerTyr: 1.927 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	6.026ThrAla: 6.026 ± 0.048	0.528ThrCys: 0.528 ± 0.013	2.954ThrAsp: 2.954 ± 0.031	2.793ThrGlu: 2.793 ± 0.031	2.074ThrPhe: 2.074 ± 0.028	4.14ThrGly: 4.14 ± 0.044	1.252ThrHis: 1.252 ± 0.021	2.538ThrIle: 2.538 ± 0.024	2.506ThrLys: 2.506 ± 0.027	5.388ThrLeu: 5.388 ± 0.039	1.049ThrMet: 1.049 ± 0.018	1.889ThrAsn: 1.889 ± 0.023	4.285ThrPro: 4.285 ± 0.049	2.128ThrGln: 2.128 ± 0.027	3.137ThrArg: 3.137 ± 0.033	6.207ThrSer: 6.207 ± 0.051	3.993ThrThr: 3.993 ± 0.042	3.461ThrVal: 3.461 ± 0.035	0.653ThrTrp: 0.653 ± 0.014	1.327ThrTyr: 1.327 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.956ValAla: 5.956 ± 0.047	0.647ValCys: 0.647 ± 0.014	3.87ValAsp: 3.87 ± 0.04	4.023ValGlu: 4.023 ± 0.039	2.131ValPhe: 2.131 ± 0.031	4.193ValGly: 4.193 ± 0.039	1.385ValHis: 1.385 ± 0.02	2.468ValIle: 2.468 ± 0.029	3.005ValLys: 3.005 ± 0.035	5.645ValLeu: 5.645 ± 0.048	1.17ValMet: 1.17 ± 0.02	1.942ValAsn: 1.942 ± 0.026	3.465ValPro: 3.465 ± 0.035	2.459ValGln: 2.459 ± 0.031	3.699ValArg: 3.699 ± 0.038	4.632ValSer: 4.632 ± 0.034	3.195ValThr: 3.195 ± 0.035	4.272ValVal: 4.272 ± 0.042	0.793ValTrp: 0.793 ± 0.019	1.47ValTyr: 1.47 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	0.98TrpAla: 0.98 ± 0.02	0.16TrpCys: 0.16 ± 0.007	0.77TrpAsp: 0.77 ± 0.016	0.628TrpGlu: 0.628 ± 0.015	0.45TrpPhe: 0.45 ± 0.012	0.768TrpGly: 0.768 ± 0.014	0.267TrpHis: 0.267 ± 0.009	0.617TrpIle: 0.617 ± 0.015	0.653TrpLys: 0.653 ± 0.016	1.187TrpLeu: 1.187 ± 0.02	0.303TrpMet: 0.303 ± 0.01	0.52TrpAsn: 0.52 ± 0.014	0.488TrpPro: 0.488 ± 0.013	0.512TrpGln: 0.512 ± 0.013	0.771TrpArg: 0.771 ± 0.018	1.041TrpSer: 1.041 ± 0.019	0.773TrpThr: 0.773 ± 0.016	0.674TrpVal: 0.674 ± 0.015	0.226TrpTrp: 0.226 ± 0.009	0.331TrpTyr: 0.331 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.201TyrAla: 2.201 ± 0.023	0.301TyrCys: 0.301 ± 0.01	1.528TyrAsp: 1.528 ± 0.025	1.281TyrGlu: 1.281 ± 0.02	0.942TyrPhe: 0.942 ± 0.019	1.854TyrGly: 1.854 ± 0.03	0.588TyrHis: 0.588 ± 0.014	1.023TyrIle: 1.023 ± 0.016	0.95TyrLys: 0.95 ± 0.02	2.288TyrLeu: 2.288 ± 0.027	0.443TyrMet: 0.443 ± 0.013	0.848TyrAsn: 0.848 ± 0.022	1.219TyrPro: 1.219 ± 0.023	0.91TyrGln: 0.91 ± 0.017	1.495TyrArg: 1.495 ± 0.024	1.737TyrSer: 1.737 ± 0.022	1.354TyrThr: 1.354 ± 0.023	1.479TyrVal: 1.479 ± 0.023	0.321TyrTrp: 0.321 ± 0.011	0.691TyrTyr: 0.691 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.008XaaXaa: 0.008 ± 0.005

Statistics based on 5765 proteins (3250758 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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