Amino acid dipepetide frequency for Pelargonium flower break virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.863AlaAla: 5.863 ± 1.166
1.675AlaCys: 1.675 ± 0.565
4.188AlaAsp: 4.188 ± 0.883
5.863AlaGlu: 5.863 ± 1.118
1.675AlaPhe: 1.675 ± 0.565
2.931AlaGly: 2.931 ± 0.583
0.0AlaHis: 0.0 ± 0.0
2.094AlaIle: 2.094 ± 0.799
5.025AlaLys: 5.025 ± 1.599
5.863AlaLeu: 5.863 ± 0.564
2.094AlaMet: 2.094 ± 0.559
2.931AlaAsn: 2.931 ± 0.766
3.769AlaPro: 3.769 ± 0.448
3.769AlaGln: 3.769 ± 0.716
3.35AlaArg: 3.35 ± 0.352
5.025AlaSer: 5.025 ± 0.775
2.513AlaThr: 2.513 ± 1.263
5.025AlaVal: 5.025 ± 1.234
3.769AlaTrp: 3.769 ± 0.689
3.35AlaTyr: 3.35 ± 0.352
0.0AlaXaa: 0.0 ± 0.0
Cys
1.256CysAla: 1.256 ± 0.484
0.0CysCys: 0.0 ± 0.0
1.256CysAsp: 1.256 ± 0.484
0.0CysGlu: 0.0 ± 0.0
0.838CysPhe: 0.838 ± 0.283
0.838CysGly: 0.838 ± 0.283
0.0CysHis: 0.0 ± 0.0
0.838CysIle: 0.838 ± 0.283
0.838CysLys: 0.838 ± 0.283
2.513CysLeu: 2.513 ± 0.848
0.0CysMet: 0.0 ± 0.0
0.419CysAsn: 0.419 ± 0.501
1.675CysPro: 1.675 ± 0.565
1.675CysGln: 1.675 ± 0.647
2.931CysArg: 2.931 ± 0.742
2.094CysSer: 2.094 ± 0.799
0.0CysThr: 0.0 ± 0.0
0.838CysVal: 0.838 ± 0.283
0.0CysTrp: 0.0 ± 0.0
1.675CysTyr: 1.675 ± 0.565
0.0CysXaa: 0.0 ± 0.0
Asp
4.606AspAla: 4.606 ± 1.139
1.675AspCys: 1.675 ± 0.565
1.256AspAsp: 1.256 ± 0.377
3.35AspGlu: 3.35 ± 0.352
0.419AspPhe: 0.419 ± 0.501
3.35AspGly: 3.35 ± 0.732
2.094AspHis: 2.094 ± 0.559
2.094AspIle: 2.094 ± 0.559
2.094AspLys: 2.094 ± 0.44
2.513AspLeu: 2.513 ± 0.692
2.513AspMet: 2.513 ± 0.848
1.675AspAsn: 1.675 ± 1.029
4.188AspPro: 4.188 ± 0.883
1.675AspGln: 1.675 ± 0.565
2.094AspArg: 2.094 ± 0.559
2.931AspSer: 2.931 ± 1.204
0.838AspThr: 0.838 ± 1.003
2.094AspVal: 2.094 ± 0.789
0.0AspTrp: 0.0 ± 0.0
1.675AspTyr: 1.675 ± 0.43
0.0AspXaa: 0.0 ± 0.0
Glu
2.094GluAla: 2.094 ± 0.559
0.0GluCys: 0.0 ± 0.0
0.838GluAsp: 0.838 ± 0.62
5.444GluGlu: 5.444 ± 1.554
4.188GluPhe: 4.188 ± 0.577
2.094GluGly: 2.094 ± 0.559
3.769GluHis: 3.769 ± 0.974
2.931GluIle: 2.931 ± 0.78
4.606GluLys: 4.606 ± 1.227
7.119GluLeu: 7.119 ± 0.94
4.188GluMet: 4.188 ± 1.118
0.838GluAsn: 0.838 ± 0.283
3.35GluPro: 3.35 ± 1.006
0.0GluGln: 0.0 ± 0.0
3.35GluArg: 3.35 ± 0.983
1.256GluSer: 1.256 ± 0.377
1.256GluThr: 1.256 ± 0.577
6.7GluVal: 6.7 ± 1.43
1.256GluTrp: 1.256 ± 0.377
2.094GluTyr: 2.094 ± 0.44
0.0GluXaa: 0.0 ± 0.0
Phe
3.769PheAla: 3.769 ± 0.974
2.513PheCys: 2.513 ± 0.848
2.094PheAsp: 2.094 ± 0.44
2.094PheGlu: 2.094 ± 0.44
1.256PhePhe: 1.256 ± 0.377
5.025PheGly: 5.025 ± 1.283
0.838PheHis: 0.838 ± 0.283
2.094PheIle: 2.094 ± 0.585
1.675PheLys: 1.675 ± 0.565
2.513PheLeu: 2.513 ± 0.565
0.419PheMet: 0.419 ± 0.542
2.931PheAsn: 2.931 ± 1.095
2.513PhePro: 2.513 ± 0.273
1.256PheGln: 1.256 ± 0.377
1.256PheArg: 1.256 ± 0.704
3.769PheSer: 3.769 ± 0.716
2.931PheThr: 2.931 ± 0.766
4.606PheVal: 4.606 ± 1.227
0.0PheTrp: 0.0 ± 0.0
0.838PheTyr: 0.838 ± 0.283
0.0PheXaa: 0.0 ± 0.0
Gly
1.675GlyAla: 1.675 ± 0.841
0.838GlyCys: 0.838 ± 0.283
4.606GlyAsp: 4.606 ± 1.227
1.256GlyGlu: 1.256 ± 0.377
3.35GlyPhe: 3.35 ± 0.769
6.281GlyGly: 6.281 ± 1.845
0.838GlyHis: 0.838 ± 0.62
0.838GlyIle: 0.838 ± 0.283
7.956GlyLys: 7.956 ± 1.801
8.794GlyLeu: 8.794 ± 1.707
1.256GlyMet: 1.256 ± 0.377
2.094GlyAsn: 2.094 ± 1.368
2.513GlyPro: 2.513 ± 0.273
0.838GlyGln: 0.838 ± 0.62
5.025GlyArg: 5.025 ± 0.775
5.863GlySer: 5.863 ± 1.295
4.188GlyThr: 4.188 ± 0.497
7.956GlyVal: 7.956 ± 1.097
1.256GlyTrp: 1.256 ± 0.377
2.094GlyTyr: 2.094 ± 0.44
0.0GlyXaa: 0.0 ± 0.0
His
2.094HisAla: 2.094 ± 0.559
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.513HisGlu: 2.513 ± 0.968
1.675HisPhe: 1.675 ± 0.763
1.675HisGly: 1.675 ± 0.841
2.513HisHis: 2.513 ± 0.968
2.513HisIle: 2.513 ± 0.783
1.256HisLys: 1.256 ± 0.484
3.769HisLeu: 3.769 ± 0.902
0.0HisMet: 0.0 ± 0.0
1.675HisAsn: 1.675 ± 0.647
0.838HisPro: 0.838 ± 0.283
0.0HisGln: 0.0 ± 0.0
1.256HisArg: 1.256 ± 0.484
4.606HisSer: 4.606 ± 1.227
2.931HisThr: 2.931 ± 0.742
1.675HisVal: 1.675 ± 0.565
0.838HisTrp: 0.838 ± 0.283
0.838HisTyr: 0.838 ± 0.62
0.0HisXaa: 0.0 ± 0.0
Ile
3.769IleAla: 3.769 ± 0.974
1.256IleCys: 1.256 ± 0.377
0.419IleAsp: 0.419 ± 0.659
1.675IleGlu: 1.675 ± 0.565
1.256IlePhe: 1.256 ± 0.484
4.188IleGly: 4.188 ± 0.663
1.675IleHis: 1.675 ± 0.763
2.094IleIle: 2.094 ± 0.799
0.838IleLys: 0.838 ± 0.283
2.513IleLeu: 2.513 ± 1.86
0.419IleMet: 0.419 ± 0.294
2.513IleAsn: 2.513 ± 0.876
0.838IlePro: 0.838 ± 0.283
1.256IleGln: 1.256 ± 0.377
3.769IleArg: 3.769 ± 0.607
3.769IleSer: 3.769 ± 0.98
2.931IleThr: 2.931 ± 0.636
0.838IleVal: 0.838 ± 0.929
1.256IleTrp: 1.256 ± 0.485
0.838IleTyr: 0.838 ± 0.62
0.0IleXaa: 0.0 ± 0.0
Lys
3.35LysAla: 3.35 ± 0.764
2.094LysCys: 2.094 ± 0.559
7.119LysAsp: 7.119 ± 1.507
3.35LysGlu: 3.35 ± 0.352
2.513LysPhe: 2.513 ± 0.848
3.769LysGly: 3.769 ± 0.536
2.513LysHis: 2.513 ± 0.848
1.256LysIle: 1.256 ± 0.577
5.025LysLys: 5.025 ± 0.838
2.513LysLeu: 2.513 ± 0.755
0.838LysMet: 0.838 ± 0.489
4.188LysAsn: 4.188 ± 0.577
0.0LysPro: 0.0 ± 0.0
2.931LysGln: 2.931 ± 0.78
0.419LysArg: 0.419 ± 0.659
4.606LysSer: 4.606 ± 1.364
2.094LysThr: 2.094 ± 0.44
2.094LysVal: 2.094 ± 0.843
0.419LysTrp: 0.419 ± 0.501
2.513LysTyr: 2.513 ± 0.273
1.256LysXaa: 1.256 ± 0.485
Leu
11.307LeuAla: 11.307 ± 2.085
0.0LeuCys: 0.0 ± 0.0
2.931LeuAsp: 2.931 ± 0.636
7.119LeuGlu: 7.119 ± 1.274
4.188LeuPhe: 4.188 ± 0.577
2.931LeuGly: 2.931 ± 0.797
0.0LeuHis: 0.0 ± 0.0
4.188LeuIle: 4.188 ± 1.427
4.188LeuLys: 4.188 ± 0.88
6.281LeuLeu: 6.281 ± 1.618
1.675LeuMet: 1.675 ± 0.587
1.675LeuAsn: 1.675 ± 1.054
4.606LeuPro: 4.606 ± 0.723
1.675LeuGln: 1.675 ± 0.647
8.375LeuArg: 8.375 ± 1.389
7.119LeuSer: 7.119 ± 1.762
7.538LeuThr: 7.538 ± 1.645
9.631LeuVal: 9.631 ± 1.849
0.838LeuTrp: 0.838 ± 0.62
0.419LeuTyr: 0.419 ± 0.501
0.0LeuXaa: 0.0 ± 0.0
Met
3.35MetAla: 3.35 ± 0.732
0.0MetCys: 0.0 ± 0.0
1.675MetAsp: 1.675 ± 0.43
0.419MetGlu: 0.419 ± 0.501
0.0MetPhe: 0.0 ± 0.0
1.675MetGly: 1.675 ± 0.647
0.0MetHis: 0.0 ± 0.0
0.838MetIle: 0.838 ± 0.283
3.769MetLys: 3.769 ± 0.974
2.094MetLeu: 2.094 ± 0.559
0.0MetMet: 0.0 ± 0.0
2.513MetAsn: 2.513 ± 0.273
1.675MetPro: 1.675 ± 0.647
0.419MetGln: 0.419 ± 0.501
0.838MetArg: 0.838 ± 0.62
2.513MetSer: 2.513 ± 0.848
0.838MetThr: 0.838 ± 0.283
2.931MetVal: 2.931 ± 0.788
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.35AsnAla: 3.35 ± 1.006
1.675AsnCys: 1.675 ± 0.565
1.256AsnAsp: 1.256 ± 0.704
1.675AsnGlu: 1.675 ± 0.763
0.419AsnPhe: 0.419 ± 0.659
5.025AsnGly: 5.025 ± 0.689
2.931AsnHis: 2.931 ± 0.788
0.419AsnIle: 0.419 ± 0.659
1.256AsnLys: 1.256 ± 0.377
5.025AsnLeu: 5.025 ± 1.067
1.256AsnMet: 1.256 ± 0.484
0.838AsnAsn: 0.838 ± 0.283
0.838AsnPro: 0.838 ± 1.003
0.0AsnGln: 0.0 ± 0.0
2.513AsnArg: 2.513 ± 0.942
5.025AsnSer: 5.025 ± 0.641
3.35AsnThr: 3.35 ± 1.682
1.256AsnVal: 1.256 ± 0.377
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.931ProAla: 2.931 ± 1.204
0.838ProCys: 0.838 ± 0.283
5.025ProAsp: 5.025 ± 0.775
2.094ProGlu: 2.094 ± 0.559
3.769ProPhe: 3.769 ± 0.902
2.513ProGly: 2.513 ± 0.273
0.0ProHis: 0.0 ± 0.0
0.419ProIle: 0.419 ± 0.501
1.675ProLys: 1.675 ± 0.565
4.188ProLeu: 4.188 ± 1.136
0.0ProMet: 0.0 ± 0.0
0.838ProAsn: 0.838 ± 0.62
2.094ProPro: 2.094 ± 0.585
1.256ProGln: 1.256 ± 0.377
3.35ProArg: 3.35 ± 0.769
5.444ProSer: 5.444 ± 1.15
0.838ProThr: 0.838 ± 1.003
7.119ProVal: 7.119 ± 1.127
0.0ProTrp: 0.0 ± 0.0
0.419ProTyr: 0.419 ± 0.501
0.0ProXaa: 0.0 ± 0.0
Gln
0.419GlnAla: 0.419 ± 0.501
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.931GlnGlu: 2.931 ± 0.742
1.675GlnPhe: 1.675 ± 0.565
0.0GlnGly: 0.0 ± 0.0
4.188GlnHis: 4.188 ± 0.497
0.838GlnIle: 0.838 ± 0.283
0.838GlnLys: 0.838 ± 0.929
3.35GlnLeu: 3.35 ± 0.352
2.513GlnMet: 2.513 ± 0.714
1.675GlnAsn: 1.675 ± 0.565
0.838GlnPro: 0.838 ± 0.283
1.675GlnGln: 1.675 ± 0.43
2.931GlnArg: 2.931 ± 0.788
1.256GlnSer: 1.256 ± 1.504
0.419GlnThr: 0.419 ± 0.501
0.419GlnVal: 0.419 ± 0.501
1.675GlnTrp: 1.675 ± 0.647
1.675GlnTyr: 1.675 ± 0.647
0.0GlnXaa: 0.0 ± 0.0
Arg
4.606ArgAla: 4.606 ± 1.477
1.256ArgCys: 1.256 ± 0.484
3.35ArgAsp: 3.35 ± 0.352
5.444ArgGlu: 5.444 ± 1.672
7.956ArgPhe: 7.956 ± 1.029
2.931ArgGly: 2.931 ± 1.249
2.094ArgHis: 2.094 ± 0.559
3.35ArgIle: 3.35 ± 0.764
5.444ArgLys: 5.444 ± 1.491
5.863ArgLeu: 5.863 ± 0.857
0.838ArgMet: 0.838 ± 0.283
0.419ArgAsn: 0.419 ± 0.501
1.675ArgPro: 1.675 ± 0.647
1.675ArgGln: 1.675 ± 0.43
6.281ArgArg: 6.281 ± 0.881
5.025ArgSer: 5.025 ± 0.662
2.513ArgThr: 2.513 ± 0.85
8.794ArgVal: 8.794 ± 1.185
0.0ArgTrp: 0.0 ± 0.0
3.35ArgTyr: 3.35 ± 0.983
0.0ArgXaa: 0.0 ± 0.0
Ser
4.188SerAla: 4.188 ± 0.663
2.094SerCys: 2.094 ± 0.44
2.513SerAsp: 2.513 ± 2.679
2.931SerGlu: 2.931 ± 0.636
5.025SerPhe: 5.025 ± 1.098
5.444SerGly: 5.444 ± 1.946
2.094SerHis: 2.094 ± 0.559
0.838SerIle: 0.838 ± 0.62
3.769SerLys: 3.769 ± 1.313
6.281SerLeu: 6.281 ± 0.542
2.094SerMet: 2.094 ± 0.585
2.931SerAsn: 2.931 ± 0.589
5.444SerPro: 5.444 ± 0.398
3.35SerGln: 3.35 ± 0.493
4.606SerArg: 4.606 ± 0.723
7.119SerSer: 7.119 ± 3.869
6.7SerThr: 6.7 ± 2.474
10.469SerVal: 10.469 ± 2.563
4.188SerTrp: 4.188 ± 0.857
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.025ThrAla: 5.025 ± 1.856
0.838ThrCys: 0.838 ± 0.62
0.419ThrAsp: 0.419 ± 0.501
0.0ThrGlu: 0.0 ± 0.0
2.094ThrPhe: 2.094 ± 0.585
4.606ThrGly: 4.606 ± 1.179
2.931ThrHis: 2.931 ± 0.589
2.513ThrIle: 2.513 ± 0.273
2.094ThrLys: 2.094 ± 0.559
6.281ThrLeu: 6.281 ± 1.428
0.419ThrMet: 0.419 ± 0.501
0.0ThrAsn: 0.0 ± 0.0
4.606ThrPro: 4.606 ± 0.953
0.838ThrGln: 0.838 ± 1.003
3.35ThrArg: 3.35 ± 1.052
4.188ThrSer: 4.188 ± 2.48
4.188ThrThr: 4.188 ± 2.665
3.769ThrVal: 3.769 ± 1.344
0.0ThrTrp: 0.0 ± 0.0
1.675ThrTyr: 1.675 ± 0.841
0.0ThrXaa: 0.0 ± 0.0
Val
5.863ValAla: 5.863 ± 2.462
2.931ValCys: 2.931 ± 0.766
2.513ValAsp: 2.513 ± 0.755
6.7ValGlu: 6.7 ± 1.708
2.094ValPhe: 2.094 ± 0.559
9.213ValGly: 9.213 ± 1.609
3.35ValHis: 3.35 ± 1.006
5.444ValIle: 5.444 ± 1.499
1.256ValLys: 1.256 ± 0.377
2.094ValLeu: 2.094 ± 0.585
3.769ValMet: 3.769 ± 0.902
4.606ValAsn: 4.606 ± 1.15
2.513ValPro: 2.513 ± 1.6
2.094ValGln: 2.094 ± 0.559
11.307ValArg: 11.307 ± 1.833
7.956ValSer: 7.956 ± 2.267
2.513ValThr: 2.513 ± 1.961
13.819ValVal: 13.819 ± 3.29
0.419ValTrp: 0.419 ± 0.501
3.35ValTyr: 3.35 ± 0.769
0.0ValXaa: 0.0 ± 0.0
Trp
0.419TrpAla: 0.419 ± 0.501
0.0TrpCys: 0.0 ± 0.0
0.838TrpAsp: 0.838 ± 0.283
0.838TrpGlu: 0.838 ± 0.62
0.0TrpPhe: 0.0 ± 0.0
2.094TrpGly: 2.094 ± 0.559
0.0TrpHis: 0.0 ± 0.0
1.675TrpIle: 1.675 ± 0.43
0.0TrpLys: 0.0 ± 0.0
2.094TrpLeu: 2.094 ± 0.585
0.838TrpMet: 0.838 ± 0.283
2.094TrpAsn: 2.094 ± 0.559
0.0TrpPro: 0.0 ± 0.0
2.094TrpGln: 2.094 ± 0.559
0.838TrpArg: 0.838 ± 0.283
0.419TrpSer: 0.419 ± 0.501
0.0TrpThr: 0.0 ± 0.0
1.256TrpVal: 1.256 ± 0.858
1.256TrpTrp: 1.256 ± 0.484
0.419TrpTyr: 0.419 ± 0.501
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.838TyrAla: 0.838 ± 1.003
0.0TyrCys: 0.0 ± 0.0
0.838TyrAsp: 0.838 ± 0.283
1.675TyrGlu: 1.675 ± 0.565
0.0TyrPhe: 0.0 ± 0.0
2.094TyrGly: 2.094 ± 1.332
0.838TyrHis: 0.838 ± 0.283
0.838TyrIle: 0.838 ± 0.62
1.256TyrLys: 1.256 ± 0.377
5.444TyrLeu: 5.444 ± 0.854
0.0TyrMet: 0.0 ± 0.0
1.256TyrAsn: 1.256 ± 0.377
0.838TyrPro: 0.838 ± 0.62
0.838TyrGln: 0.838 ± 0.283
5.025TyrArg: 5.025 ± 0.838
1.675TyrSer: 1.675 ± 0.647
1.256TyrThr: 1.256 ± 0.704
2.513TyrVal: 2.513 ± 0.755
0.0TyrTrp: 0.0 ± 0.0
0.838TyrTyr: 0.838 ± 0.283
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.838XaaGly: 0.838 ± 0.283
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.419XaaSer: 0.419 ± 0.294
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2389 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski