Amino acid dipepetide frequency for Cribrihabitans marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.458AlaAla: 17.458 ± 0.175	1.131AlaCys: 1.131 ± 0.033	7.246AlaAsp: 7.246 ± 0.086	8.832AlaGlu: 8.832 ± 0.105	4.194AlaPhe: 4.194 ± 0.06	11.34AlaGly: 11.34 ± 0.106	2.434AlaHis: 2.434 ± 0.048	5.635AlaIle: 5.635 ± 0.071	3.03AlaLys: 3.03 ± 0.062	14.31AlaLeu: 14.31 ± 0.155	3.749AlaMet: 3.749 ± 0.057	2.454AlaAsn: 2.454 ± 0.046	6.108AlaPro: 6.108 ± 0.084	4.578AlaGln: 4.578 ± 0.069	10.248AlaArg: 10.248 ± 0.126	5.164AlaSer: 5.164 ± 0.068	5.637AlaThr: 5.637 ± 0.07	8.502AlaVal: 8.502 ± 0.1	1.481AlaTrp: 1.481 ± 0.04	2.536AlaTyr: 2.536 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	1.185CysAla: 1.185 ± 0.039	0.098CysCys: 0.098 ± 0.01	0.646CysAsp: 0.646 ± 0.021	0.464CysGlu: 0.464 ± 0.02	0.3CysPhe: 0.3 ± 0.016	0.986CysGly: 0.986 ± 0.033	0.292CysHis: 0.292 ± 0.017	0.398CysIle: 0.398 ± 0.017	0.2CysLys: 0.2 ± 0.012	0.873CysLeu: 0.873 ± 0.025	0.153CysMet: 0.153 ± 0.011	0.228CysAsn: 0.228 ± 0.014	0.527CysPro: 0.527 ± 0.026	0.222CysGln: 0.222 ± 0.012	0.643CysArg: 0.643 ± 0.024	0.441CysSer: 0.441 ± 0.017	0.442CysThr: 0.442 ± 0.021	0.61CysVal: 0.61 ± 0.023	0.126CysTrp: 0.126 ± 0.009	0.207CysTyr: 0.207 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.766AspAla: 7.766 ± 0.082	0.593AspCys: 0.593 ± 0.02	3.466AspAsp: 3.466 ± 0.072	3.672AspGlu: 3.672 ± 0.059	2.311AspPhe: 2.311 ± 0.039	5.942AspGly: 5.942 ± 0.092	1.419AspHis: 1.419 ± 0.038	2.996AspIle: 2.996 ± 0.051	1.722AspLys: 1.722 ± 0.043	6.872AspLeu: 6.872 ± 0.097	1.626AspMet: 1.626 ± 0.035	1.201AspAsn: 1.201 ± 0.029	4.235AspPro: 4.235 ± 0.067	1.807AspGln: 1.807 ± 0.038	5.206AspArg: 5.206 ± 0.075	2.346AspSer: 2.346 ± 0.047	3.039AspThr: 3.039 ± 0.054	4.149AspVal: 4.149 ± 0.059	1.306AspTrp: 1.306 ± 0.035	1.532AspTyr: 1.532 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	8.424GluAla: 8.424 ± 0.108	0.362GluCys: 0.362 ± 0.018	3.542GluAsp: 3.542 ± 0.054	3.508GluGlu: 3.508 ± 0.069	1.928GluPhe: 1.928 ± 0.04	4.633GluGly: 4.633 ± 0.059	1.15GluHis: 1.15 ± 0.03	3.789GluIle: 3.789 ± 0.054	1.891GluLys: 1.891 ± 0.048	5.308GluLeu: 5.308 ± 0.072	1.873GluMet: 1.873 ± 0.036	1.586GluAsn: 1.586 ± 0.038	2.721GluPro: 2.721 ± 0.053	2.039GluGln: 2.039 ± 0.044	4.596GluArg: 4.596 ± 0.066	2.223GluSer: 2.223 ± 0.047	3.947GluThr: 3.947 ± 0.06	4.335GluVal: 4.335 ± 0.07	0.74GluTrp: 0.74 ± 0.026	1.054GluTyr: 1.054 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.446PheAla: 4.446 ± 0.064	0.441PheCys: 0.441 ± 0.021	2.972PheAsp: 2.972 ± 0.049	2.222PheGlu: 2.222 ± 0.038	1.382PhePhe: 1.382 ± 0.042	3.603PheGly: 3.603 ± 0.054	0.765PheHis: 0.765 ± 0.027	1.479PheIle: 1.479 ± 0.032	0.835PheLys: 0.835 ± 0.027	3.47PheLeu: 3.47 ± 0.064	0.815PheMet: 0.815 ± 0.029	0.954PheAsn: 0.954 ± 0.027	1.495PhePro: 1.495 ± 0.036	1.075PheGln: 1.075 ± 0.027	2.377PheArg: 2.377 ± 0.043	2.034PheSer: 2.034 ± 0.045	1.951PheThr: 1.951 ± 0.037	2.656PheVal: 2.656 ± 0.053	0.587PheTrp: 0.587 ± 0.022	0.915PheTyr: 0.915 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	10.199GlyAla: 10.199 ± 0.099	0.902GlyCys: 0.902 ± 0.031	5.195GlyAsp: 5.195 ± 0.073	4.725GlyGlu: 4.725 ± 0.072	3.831GlyPhe: 3.831 ± 0.059	7.658GlyGly: 7.658 ± 0.12	2.028GlyHis: 2.028 ± 0.04	4.422GlyIle: 4.422 ± 0.064	2.858GlyLys: 2.858 ± 0.054	9.621GlyLeu: 9.621 ± 0.11	2.605GlyMet: 2.605 ± 0.052	2.087GlyAsn: 2.087 ± 0.048	4.027GlyPro: 4.027 ± 0.061	3.242GlyGln: 3.242 ± 0.056	6.339GlyArg: 6.339 ± 0.076	4.171GlySer: 4.171 ± 0.067	4.584GlyThr: 4.584 ± 0.065	6.214GlyVal: 6.214 ± 0.07	1.597GlyTrp: 1.597 ± 0.034	2.317GlyTyr: 2.317 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.356HisAla: 2.356 ± 0.045	0.253HisCys: 0.253 ± 0.014	1.355HisAsp: 1.355 ± 0.031	1.064HisGlu: 1.064 ± 0.031	0.816HisPhe: 0.816 ± 0.028	2.011HisGly: 2.011 ± 0.046	0.571HisHis: 0.571 ± 0.022	0.863HisIle: 0.863 ± 0.028	0.529HisLys: 0.529 ± 0.02	2.255HisLeu: 2.255 ± 0.048	0.551HisMet: 0.551 ± 0.021	0.426HisAsn: 0.426 ± 0.018	1.381HisPro: 1.381 ± 0.033	0.575HisGln: 0.575 ± 0.023	1.496HisArg: 1.496 ± 0.036	0.949HisSer: 0.949 ± 0.028	0.811HisThr: 0.811 ± 0.028	1.657HisVal: 1.657 ± 0.038	0.357HisTrp: 0.357 ± 0.017	0.521HisTyr: 0.521 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.724IleAla: 6.724 ± 0.084	0.624IleCys: 0.624 ± 0.023	3.427IleAsp: 3.427 ± 0.055	3.427IleGlu: 3.427 ± 0.054	1.546IlePhe: 1.546 ± 0.039	4.675IleGly: 4.675 ± 0.068	0.941IleHis: 0.941 ± 0.026	1.865IleIle: 1.865 ± 0.045	1.202IleLys: 1.202 ± 0.035	4.792IleLeu: 4.792 ± 0.08	0.965IleMet: 0.965 ± 0.033	1.187IleAsn: 1.187 ± 0.034	2.305IlePro: 2.305 ± 0.05	1.108IleGln: 1.108 ± 0.031	3.416IleArg: 3.416 ± 0.058	2.712IleSer: 2.712 ± 0.05	2.526IleThr: 2.526 ± 0.047	3.649IleVal: 3.649 ± 0.062	0.733IleTrp: 0.733 ± 0.027	1.067IleTyr: 1.067 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.525LysAla: 3.525 ± 0.063	0.18LysCys: 0.18 ± 0.012	1.573LysAsp: 1.573 ± 0.041	1.384LysGlu: 1.384 ± 0.04	0.82LysPhe: 0.82 ± 0.025	2.355LysGly: 2.355 ± 0.046	0.521LysHis: 0.521 ± 0.022	1.342LysIle: 1.342 ± 0.034	1.029LysLys: 1.029 ± 0.039	2.639LysLeu: 2.639 ± 0.047	0.777LysMet: 0.777 ± 0.023	0.663LysAsn: 0.663 ± 0.026	1.654LysPro: 1.654 ± 0.042	0.84LysGln: 0.84 ± 0.027	2.064LysArg: 2.064 ± 0.047	1.655LysSer: 1.655 ± 0.041	1.724LysThr: 1.724 ± 0.043	2.09LysVal: 2.09 ± 0.045	0.359LysTrp: 0.359 ± 0.019	0.592LysTyr: 0.592 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	13.623LeuAla: 13.623 ± 0.136	0.958LeuCys: 0.958 ± 0.031	6.663LeuAsp: 6.663 ± 0.073	5.397LeuGlu: 5.397 ± 0.065	3.546LeuPhe: 3.546 ± 0.061	8.737LeuGly: 8.737 ± 0.1	1.934LeuHis: 1.934 ± 0.034	4.94LeuIle: 4.94 ± 0.08	2.931LeuLys: 2.931 ± 0.058	9.04LeuLeu: 9.04 ± 0.12	2.576LeuMet: 2.576 ± 0.047	2.587LeuAsn: 2.587 ± 0.043	5.657LeuPro: 5.657 ± 0.074	2.734LeuGln: 2.734 ± 0.047	7.743LeuArg: 7.743 ± 0.094	6.335LeuSer: 6.335 ± 0.076	5.832LeuThr: 5.832 ± 0.068	7.109LeuVal: 7.109 ± 0.081	1.314LeuTrp: 1.314 ± 0.038	1.949LeuTyr: 1.949 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.418MetAla: 3.418 ± 0.054	0.192MetCys: 0.192 ± 0.013	1.446MetAsp: 1.446 ± 0.036	1.318MetGlu: 1.318 ± 0.035	0.797MetPhe: 0.797 ± 0.029	2.182MetGly: 2.182 ± 0.049	0.456MetHis: 0.456 ± 0.019	1.435MetIle: 1.435 ± 0.036	0.978MetLys: 0.978 ± 0.03	2.568MetLeu: 2.568 ± 0.05	0.745MetMet: 0.745 ± 0.029	0.819MetAsn: 0.819 ± 0.025	1.541MetPro: 1.541 ± 0.036	0.978MetGln: 0.978 ± 0.027	2.054MetArg: 2.054 ± 0.041	1.697MetSer: 1.697 ± 0.034	2.037MetThr: 2.037 ± 0.045	1.845MetVal: 1.845 ± 0.041	0.238MetTrp: 0.238 ± 0.015	0.333MetTyr: 0.333 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.836AsnAla: 2.836 ± 0.052	0.242AsnCys: 0.242 ± 0.014	1.316AsnAsp: 1.316 ± 0.036	1.135AsnGlu: 1.135 ± 0.034	0.857AsnPhe: 0.857 ± 0.029	2.199AsnGly: 2.199 ± 0.045	0.456AsnHis: 0.456 ± 0.019	1.208AsnIle: 1.208 ± 0.032	0.595AsnLys: 0.595 ± 0.025	2.39AsnLeu: 2.39 ± 0.045	0.658AsnMet: 0.658 ± 0.023	0.604AsnAsn: 0.604 ± 0.026	1.791AsnPro: 1.791 ± 0.04	0.654AsnGln: 0.654 ± 0.026	1.8AsnArg: 1.8 ± 0.036	1.073AsnSer: 1.073 ± 0.03	1.208AsnThr: 1.208 ± 0.03	1.653AsnVal: 1.653 ± 0.041	0.414AsnTrp: 0.414 ± 0.017	0.608AsnTyr: 0.608 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.14ProAla: 6.14 ± 0.076	0.372ProCys: 0.372 ± 0.019	4.531ProAsp: 4.531 ± 0.069	4.485ProGlu: 4.485 ± 0.074	1.957ProPhe: 1.957 ± 0.037	5.108ProGly: 5.108 ± 0.057	1.128ProHis: 1.128 ± 0.032	2.114ProIle: 2.114 ± 0.038	1.369ProLys: 1.369 ± 0.034	4.703ProLeu: 4.703 ± 0.066	1.341ProMet: 1.341 ± 0.03	1.208ProAsn: 1.208 ± 0.031	2.57ProPro: 2.57 ± 0.059	1.694ProGln: 1.694 ± 0.041	3.191ProArg: 3.191 ± 0.061	2.381ProSer: 2.381 ± 0.038	2.282ProThr: 2.282 ± 0.041	4.442ProVal: 4.442 ± 0.069	0.709ProTrp: 0.709 ± 0.026	1.139ProTyr: 1.139 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.291GlnAla: 4.291 ± 0.056	0.212GlnCys: 0.212 ± 0.012	1.777GlnAsp: 1.777 ± 0.037	1.599GlnGlu: 1.599 ± 0.039	1.093GlnPhe: 1.093 ± 0.026	2.703GlnGly: 2.703 ± 0.048	0.544GlnHis: 0.544 ± 0.022	1.847GlnIle: 1.847 ± 0.043	0.98GlnLys: 0.98 ± 0.029	2.805GlnLeu: 2.805 ± 0.052	1.054GlnMet: 1.054 ± 0.03	0.77GlnAsn: 0.77 ± 0.022	1.683GlnPro: 1.683 ± 0.037	1.022GlnGln: 1.022 ± 0.036	2.215GlnArg: 2.215 ± 0.045	1.633GlnSer: 1.633 ± 0.039	1.705GlnThr: 1.705 ± 0.035	2.476GlnVal: 2.476 ± 0.045	0.389GlnTrp: 0.389 ± 0.019	0.552GlnTyr: 0.552 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	9.198ArgAla: 9.198 ± 0.106	0.556ArgCys: 0.556 ± 0.02	4.971ArgAsp: 4.971 ± 0.064	4.042ArgGlu: 4.042 ± 0.07	2.839ArgPhe: 2.839 ± 0.052	5.193ArgGly: 5.193 ± 0.074	1.778ArgHis: 1.778 ± 0.042	4.331ArgIle: 4.331 ± 0.062	2.312ArgLys: 2.312 ± 0.05	8.104ArgLeu: 8.104 ± 0.098	2.149ArgMet: 2.149 ± 0.043	1.869ArgAsn: 1.869 ± 0.034	3.799ArgPro: 3.799 ± 0.066	2.472ArgGln: 2.472 ± 0.047	5.911ArgArg: 5.911 ± 0.082	3.4ArgSer: 3.4 ± 0.052	3.147ArgThr: 3.147 ± 0.045	5.125ArgVal: 5.125 ± 0.055	1.037ArgTrp: 1.037 ± 0.028	1.591ArgTyr: 1.591 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.712SerAla: 5.712 ± 0.088	0.418SerCys: 0.418 ± 0.019	3.406SerAsp: 3.406 ± 0.055	2.793SerGlu: 2.793 ± 0.054	2.119SerPhe: 2.119 ± 0.041	5.379SerGly: 5.379 ± 0.075	1.082SerHis: 1.082 ± 0.027	2.114SerIle: 2.114 ± 0.04	1.259SerLys: 1.259 ± 0.037	4.658SerLeu: 4.658 ± 0.061	1.273SerMet: 1.273 ± 0.033	1.198SerAsn: 1.198 ± 0.03	2.484SerPro: 2.484 ± 0.047	1.51SerGln: 1.51 ± 0.036	3.308SerArg: 3.308 ± 0.054	2.249SerSer: 2.249 ± 0.047	2.286SerThr: 2.286 ± 0.044	3.711SerVal: 3.711 ± 0.056	0.709SerTrp: 0.709 ± 0.025	1.233SerTyr: 1.233 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	6.024ThrAla: 6.024 ± 0.072	0.481ThrCys: 0.481 ± 0.022	3.159ThrAsp: 3.159 ± 0.049	3.093ThrGlu: 3.093 ± 0.051	1.829ThrPhe: 1.829 ± 0.036	5.555ThrGly: 5.555 ± 0.072	1.073ThrHis: 1.073 ± 0.029	2.498ThrIle: 2.498 ± 0.051	1.162ThrLys: 1.162 ± 0.029	5.63ThrLeu: 5.63 ± 0.063	1.205ThrMet: 1.205 ± 0.031	1.083ThrAsn: 1.083 ± 0.029	3.322ThrPro: 3.322 ± 0.054	1.405ThrGln: 1.405 ± 0.036	3.792ThrArg: 3.792 ± 0.055	2.356ThrSer: 2.356 ± 0.042	2.472ThrThr: 2.472 ± 0.053	4.002ThrVal: 4.002 ± 0.057	0.669ThrTrp: 0.669 ± 0.025	1.178ThrTyr: 1.178 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	8.751ValAla: 8.751 ± 0.086	0.633ValCys: 0.633 ± 0.021	4.098ValAsp: 4.098 ± 0.057	4.598ValGlu: 4.598 ± 0.056	2.857ValPhe: 2.857 ± 0.053	5.37ValGly: 5.37 ± 0.077	1.357ValHis: 1.357 ± 0.035	4.081ValIle: 4.081 ± 0.063	1.934ValLys: 1.934 ± 0.043	7.585ValLeu: 7.585 ± 0.088	2.092ValMet: 2.092 ± 0.041	1.821ValAsn: 1.821 ± 0.047	3.755ValPro: 3.755 ± 0.053	2.133ValGln: 2.133 ± 0.041	4.615ValArg: 4.615 ± 0.065	4.103ValSer: 4.103 ± 0.056	4.483ValThr: 4.483 ± 0.059	5.52ValVal: 5.52 ± 0.077	0.964ValTrp: 0.964 ± 0.029	1.471ValTyr: 1.471 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.472TrpAla: 1.472 ± 0.042	0.155TrpCys: 0.155 ± 0.01	0.808TrpAsp: 0.808 ± 0.028	0.639TrpGlu: 0.639 ± 0.022	0.592TrpPhe: 0.592 ± 0.022	0.992TrpGly: 0.992 ± 0.032	0.351TrpHis: 0.351 ± 0.019	0.719TrpIle: 0.719 ± 0.023	0.431TrpLys: 0.431 ± 0.02	1.702TrpLeu: 1.702 ± 0.035	0.403TrpMet: 0.403 ± 0.019	0.43TrpAsn: 0.43 ± 0.018	0.772TrpPro: 0.772 ± 0.027	0.615TrpGln: 0.615 ± 0.022	1.154TrpArg: 1.154 ± 0.031	0.842TrpSer: 0.842 ± 0.027	0.825TrpThr: 0.825 ± 0.03	0.918TrpVal: 0.918 ± 0.03	0.233TrpTrp: 0.233 ± 0.014	0.277TrpTyr: 0.277 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.515TyrAla: 2.515 ± 0.048	0.239TyrCys: 0.239 ± 0.012	1.607TyrAsp: 1.607 ± 0.037	1.251TyrGlu: 1.251 ± 0.032	0.86TyrPhe: 0.86 ± 0.027	2.001TyrGly: 2.001 ± 0.044	0.52TyrHis: 0.52 ± 0.022	0.819TyrIle: 0.819 ± 0.027	0.539TyrLys: 0.539 ± 0.019	2.282TyrLeu: 2.282 ± 0.046	0.465TyrMet: 0.465 ± 0.018	0.521TyrAsn: 0.521 ± 0.02	1.038TyrPro: 1.038 ± 0.03	0.648TyrGln: 0.648 ± 0.02	1.655TyrArg: 1.655 ± 0.037	1.139TyrSer: 1.139 ± 0.036	1.048TyrThr: 1.048 ± 0.031	1.556TyrVal: 1.556 ± 0.034	0.369TyrTrp: 0.369 ± 0.017	0.537TyrTyr: 0.537 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4013 proteins (1261868 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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