Amino acid dipepetide frequency for Areca palm velarivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.461AlaAla: 2.461 ± 1.117
0.946AlaCys: 0.946 ± 0.378
3.407AlaAsp: 3.407 ± 0.868
3.218AlaGlu: 3.218 ± 0.927
2.082AlaPhe: 2.082 ± 0.557
1.704AlaGly: 1.704 ± 0.43
0.568AlaHis: 0.568 ± 0.355
4.164AlaIle: 4.164 ± 0.875
2.65AlaLys: 2.65 ± 0.8
4.543AlaLeu: 4.543 ± 1.464
1.136AlaMet: 1.136 ± 0.4
2.839AlaAsn: 2.839 ± 0.482
2.082AlaPro: 2.082 ± 0.769
1.704AlaGln: 1.704 ± 0.58
1.704AlaArg: 1.704 ± 0.536
2.839AlaSer: 2.839 ± 0.664
2.65AlaThr: 2.65 ± 0.82
3.407AlaVal: 3.407 ± 1.256
0.379AlaTrp: 0.379 ± 0.237
1.893AlaTyr: 1.893 ± 0.655
0.0AlaXaa: 0.0 ± 0.0
Cys
0.757CysAla: 0.757 ± 0.305
0.568CysCys: 0.568 ± 0.304
0.946CysAsp: 0.946 ± 0.374
0.757CysGlu: 0.757 ± 0.522
1.514CysPhe: 1.514 ± 0.506
0.946CysGly: 0.946 ± 0.423
0.568CysHis: 0.568 ± 0.269
0.946CysIle: 0.946 ± 0.373
1.514CysLys: 1.514 ± 0.528
2.082CysLeu: 2.082 ± 0.744
0.189CysMet: 0.189 ± 0.118
1.136CysAsn: 1.136 ± 0.408
0.568CysPro: 0.568 ± 0.355
0.568CysGln: 0.568 ± 0.343
0.946CysArg: 0.946 ± 0.298
0.946CysSer: 0.946 ± 0.232
0.757CysThr: 0.757 ± 0.309
1.704CysVal: 1.704 ± 0.73
0.379CysTrp: 0.379 ± 0.237
1.325CysTyr: 1.325 ± 0.674
0.0CysXaa: 0.0 ± 0.0
Asp
1.325AspAla: 1.325 ± 0.699
0.757AspCys: 0.757 ± 0.253
3.029AspAsp: 3.029 ± 0.623
3.407AspGlu: 3.407 ± 1.075
5.868AspPhe: 5.868 ± 1.042
1.325AspGly: 1.325 ± 0.661
1.893AspHis: 1.893 ± 0.582
5.489AspIle: 5.489 ± 0.788
4.354AspLys: 4.354 ± 0.789
7.95AspLeu: 7.95 ± 2.34
1.136AspMet: 1.136 ± 0.462
3.029AspAsn: 3.029 ± 0.747
1.514AspPro: 1.514 ± 0.668
0.946AspGln: 0.946 ± 0.425
3.029AspArg: 3.029 ± 0.512
4.354AspSer: 4.354 ± 0.783
3.786AspThr: 3.786 ± 0.568
2.461AspVal: 2.461 ± 0.701
1.136AspTrp: 1.136 ± 0.351
1.514AspTyr: 1.514 ± 0.775
0.0AspXaa: 0.0 ± 0.0
Glu
1.893GluAla: 1.893 ± 0.475
1.325GluCys: 1.325 ± 0.507
1.893GluAsp: 1.893 ± 0.384
3.218GluGlu: 3.218 ± 1.192
3.975GluPhe: 3.975 ± 0.543
2.082GluGly: 2.082 ± 0.822
1.514GluHis: 1.514 ± 0.645
5.111GluIle: 5.111 ± 0.625
1.325GluLys: 1.325 ± 0.866
5.868GluLeu: 5.868 ± 1.206
0.568GluMet: 0.568 ± 0.242
3.029GluAsn: 3.029 ± 0.587
1.136GluPro: 1.136 ± 0.389
2.839GluGln: 2.839 ± 0.721
1.893GluArg: 1.893 ± 0.38
2.839GluSer: 2.839 ± 0.385
1.893GluThr: 1.893 ± 0.542
4.164GluVal: 4.164 ± 0.682
0.757GluTrp: 0.757 ± 0.503
2.082GluTyr: 2.082 ± 0.509
0.0GluXaa: 0.0 ± 0.0
Phe
2.65PheAla: 2.65 ± 0.68
1.893PheCys: 1.893 ± 1.143
4.732PheAsp: 4.732 ± 1.038
4.164PheGlu: 4.164 ± 0.884
3.218PhePhe: 3.218 ± 0.726
3.596PheGly: 3.596 ± 0.638
0.757PheHis: 0.757 ± 0.676
4.543PheIle: 4.543 ± 0.894
5.3PheLys: 5.3 ± 0.993
4.732PheLeu: 4.732 ± 0.857
0.568PheMet: 0.568 ± 0.242
2.839PheAsn: 2.839 ± 0.657
1.136PhePro: 1.136 ± 0.339
2.271PheGln: 2.271 ± 0.54
2.082PheArg: 2.082 ± 0.795
5.111PheSer: 5.111 ± 0.866
3.596PheThr: 3.596 ± 0.764
4.354PheVal: 4.354 ± 0.894
0.568PheTrp: 0.568 ± 0.359
2.271PheTyr: 2.271 ± 0.277
0.0PheXaa: 0.0 ± 0.0
Gly
2.082GlyAla: 2.082 ± 0.549
1.325GlyCys: 1.325 ± 0.501
1.704GlyAsp: 1.704 ± 0.672
1.325GlyGlu: 1.325 ± 0.567
1.325GlyPhe: 1.325 ± 0.514
3.407GlyGly: 3.407 ± 1.164
0.757GlyHis: 0.757 ± 0.351
2.461GlyIle: 2.461 ± 0.821
3.786GlyLys: 3.786 ± 0.439
2.271GlyLeu: 2.271 ± 0.461
0.379GlyMet: 0.379 ± 0.201
2.65GlyAsn: 2.65 ± 0.478
0.757GlyPro: 0.757 ± 0.336
1.514GlyGln: 1.514 ± 0.41
2.65GlyArg: 2.65 ± 0.527
2.65GlySer: 2.65 ± 0.81
2.65GlyThr: 2.65 ± 0.885
2.082GlyVal: 2.082 ± 0.405
0.0GlyTrp: 0.0 ± 0.0
0.946GlyTyr: 0.946 ± 0.353
0.0GlyXaa: 0.0 ± 0.0
His
0.757HisAla: 0.757 ± 0.303
0.379HisCys: 0.379 ± 0.237
0.757HisAsp: 0.757 ± 0.344
0.568HisGlu: 0.568 ± 0.343
1.704HisPhe: 1.704 ± 0.595
0.568HisGly: 0.568 ± 0.249
0.757HisHis: 0.757 ± 0.327
1.514HisIle: 1.514 ± 0.437
1.893HisLys: 1.893 ± 0.605
1.893HisLeu: 1.893 ± 0.543
0.379HisMet: 0.379 ± 0.201
1.514HisAsn: 1.514 ± 0.389
1.893HisPro: 1.893 ± 0.658
0.379HisGln: 0.379 ± 0.237
0.757HisArg: 0.757 ± 0.563
2.082HisSer: 2.082 ± 0.443
1.136HisThr: 1.136 ± 0.265
0.946HisVal: 0.946 ± 0.266
0.0HisTrp: 0.0 ± 0.0
1.136HisTyr: 1.136 ± 0.388
0.0HisXaa: 0.0 ± 0.0
Ile
3.596IleAla: 3.596 ± 0.877
2.082IleCys: 2.082 ± 0.8
5.679IleAsp: 5.679 ± 0.781
2.65IleGlu: 2.65 ± 1.015
4.354IlePhe: 4.354 ± 0.959
0.757IleGly: 0.757 ± 0.249
1.514IleHis: 1.514 ± 0.654
4.921IleIle: 4.921 ± 0.781
5.3IleLys: 5.3 ± 0.827
8.139IleLeu: 8.139 ± 1.612
0.946IleMet: 0.946 ± 0.317
7.004IleAsn: 7.004 ± 1.083
3.786IlePro: 3.786 ± 0.781
2.839IleGln: 2.839 ± 0.927
3.407IleArg: 3.407 ± 0.715
7.004IleSer: 7.004 ± 0.752
5.679IleThr: 5.679 ± 0.856
7.004IleVal: 7.004 ± 1.142
0.379IleTrp: 0.379 ± 0.282
3.786IleTyr: 3.786 ± 1.148
0.0IleXaa: 0.0 ± 0.0
Lys
3.596LysAla: 3.596 ± 0.782
1.325LysCys: 1.325 ± 0.441
4.354LysAsp: 4.354 ± 0.454
1.893LysGlu: 1.893 ± 0.551
3.975LysPhe: 3.975 ± 0.976
2.65LysGly: 2.65 ± 0.635
1.136LysHis: 1.136 ± 0.499
7.004LysIle: 7.004 ± 1.084
4.354LysLys: 4.354 ± 1.096
6.057LysLeu: 6.057 ± 1.191
1.136LysMet: 1.136 ± 0.317
3.975LysAsn: 3.975 ± 0.749
2.461LysPro: 2.461 ± 0.81
2.461LysGln: 2.461 ± 0.633
1.704LysArg: 1.704 ± 0.462
5.868LysSer: 5.868 ± 1.15
4.921LysThr: 4.921 ± 1.299
3.786LysVal: 3.786 ± 0.831
0.568LysTrp: 0.568 ± 0.355
4.164LysTyr: 4.164 ± 0.869
0.0LysXaa: 0.0 ± 0.0
Leu
5.679LeuAla: 5.679 ± 0.984
2.271LeuCys: 2.271 ± 0.875
6.057LeuAsp: 6.057 ± 2.079
5.111LeuGlu: 5.111 ± 1.45
6.246LeuPhe: 6.246 ± 1.046
3.596LeuGly: 3.596 ± 0.601
1.893LeuHis: 1.893 ± 0.66
8.707LeuIle: 8.707 ± 1.603
7.004LeuLys: 7.004 ± 1.355
8.329LeuLeu: 8.329 ± 1.534
2.271LeuMet: 2.271 ± 0.533
7.004LeuAsn: 7.004 ± 0.97
3.975LeuPro: 3.975 ± 1.06
4.543LeuGln: 4.543 ± 0.963
6.246LeuArg: 6.246 ± 0.97
9.275LeuSer: 9.275 ± 1.899
5.868LeuThr: 5.868 ± 1.041
5.3LeuVal: 5.3 ± 0.888
0.757LeuTrp: 0.757 ± 0.676
4.921LeuTyr: 4.921 ± 0.731
0.0LeuXaa: 0.0 ± 0.0
Met
0.757MetAla: 0.757 ± 0.391
0.189MetCys: 0.189 ± 0.118
1.514MetAsp: 1.514 ± 0.437
1.514MetGlu: 1.514 ± 0.547
0.568MetPhe: 0.568 ± 0.386
0.568MetGly: 0.568 ± 0.259
0.0MetHis: 0.0 ± 0.0
1.325MetIle: 1.325 ± 0.505
1.704MetLys: 1.704 ± 0.403
2.082MetLeu: 2.082 ± 0.388
0.0MetMet: 0.0 ± 0.0
0.379MetAsn: 0.379 ± 0.272
0.379MetPro: 0.379 ± 0.256
0.757MetGln: 0.757 ± 0.474
0.946MetArg: 0.946 ± 0.359
1.704MetSer: 1.704 ± 0.448
0.757MetThr: 0.757 ± 0.371
1.325MetVal: 1.325 ± 0.459
0.189MetTrp: 0.189 ± 0.207
0.189MetTyr: 0.189 ± 0.221
0.0MetXaa: 0.0 ± 0.0
Asn
3.029AsnAla: 3.029 ± 0.937
0.757AsnCys: 0.757 ± 0.378
3.218AsnAsp: 3.218 ± 0.648
3.596AsnGlu: 3.596 ± 0.697
3.596AsnPhe: 3.596 ± 0.986
1.893AsnGly: 1.893 ± 0.489
0.757AsnHis: 0.757 ± 0.474
4.732AsnIle: 4.732 ± 0.998
4.921AsnLys: 4.921 ± 0.944
9.086AsnLeu: 9.086 ± 1.253
0.757AsnMet: 0.757 ± 0.387
5.489AsnAsn: 5.489 ± 1.078
3.029AsnPro: 3.029 ± 0.706
1.704AsnGln: 1.704 ± 0.715
2.65AsnArg: 2.65 ± 0.732
3.596AsnSer: 3.596 ± 0.596
4.164AsnThr: 4.164 ± 1.1
4.921AsnVal: 4.921 ± 0.633
0.189AsnTrp: 0.189 ± 0.118
3.786AsnTyr: 3.786 ± 1.003
0.0AsnXaa: 0.0 ± 0.0
Pro
2.271ProAla: 2.271 ± 0.584
0.189ProCys: 0.189 ± 0.192
2.082ProAsp: 2.082 ± 0.758
2.65ProGlu: 2.65 ± 0.703
2.082ProPhe: 2.082 ± 0.646
0.946ProGly: 0.946 ± 0.437
0.568ProHis: 0.568 ± 0.24
2.65ProIle: 2.65 ± 0.928
1.704ProLys: 1.704 ± 0.367
3.407ProLeu: 3.407 ± 0.632
0.757ProMet: 0.757 ± 0.645
3.786ProAsn: 3.786 ± 1.213
1.514ProPro: 1.514 ± 0.729
0.757ProGln: 0.757 ± 0.444
1.136ProArg: 1.136 ± 0.502
3.029ProSer: 3.029 ± 0.742
3.786ProThr: 3.786 ± 0.8
2.461ProVal: 2.461 ± 0.725
0.379ProTrp: 0.379 ± 0.256
1.704ProTyr: 1.704 ± 0.542
0.0ProXaa: 0.0 ± 0.0
Gln
1.893GlnAla: 1.893 ± 0.42
0.757GlnCys: 0.757 ± 0.344
3.218GlnAsp: 3.218 ± 1.078
1.325GlnGlu: 1.325 ± 0.585
2.271GlnPhe: 2.271 ± 0.715
0.946GlnGly: 0.946 ± 0.313
0.757GlnHis: 0.757 ± 0.345
2.461GlnIle: 2.461 ± 0.559
2.082GlnLys: 2.082 ± 0.699
5.868GlnLeu: 5.868 ± 0.969
0.946GlnMet: 0.946 ± 0.455
1.514GlnAsn: 1.514 ± 0.322
2.082GlnPro: 2.082 ± 0.567
0.946GlnGln: 0.946 ± 0.41
1.514GlnArg: 1.514 ± 0.444
3.218GlnSer: 3.218 ± 0.704
1.704GlnThr: 1.704 ± 0.591
1.704GlnVal: 1.704 ± 0.589
0.379GlnTrp: 0.379 ± 0.278
0.946GlnTyr: 0.946 ± 0.317
0.0GlnXaa: 0.0 ± 0.0
Arg
1.325ArgAla: 1.325 ± 0.47
0.379ArgCys: 0.379 ± 0.237
3.218ArgAsp: 3.218 ± 0.867
2.461ArgGlu: 2.461 ± 0.678
2.839ArgPhe: 2.839 ± 0.874
0.946ArgGly: 0.946 ± 0.437
1.704ArgHis: 1.704 ± 0.724
3.218ArgIle: 3.218 ± 0.892
3.029ArgLys: 3.029 ± 0.707
3.975ArgLeu: 3.975 ± 0.727
0.946ArgMet: 0.946 ± 0.318
3.029ArgAsn: 3.029 ± 0.777
1.514ArgPro: 1.514 ± 0.701
2.082ArgGln: 2.082 ± 0.587
2.271ArgArg: 2.271 ± 0.514
3.029ArgSer: 3.029 ± 0.608
4.354ArgThr: 4.354 ± 0.867
2.461ArgVal: 2.461 ± 0.511
0.946ArgTrp: 0.946 ± 0.342
1.704ArgTyr: 1.704 ± 0.767
0.0ArgXaa: 0.0 ± 0.0
Ser
2.839SerAla: 2.839 ± 0.652
0.946SerCys: 0.946 ± 0.232
2.082SerAsp: 2.082 ± 0.587
4.354SerGlu: 4.354 ± 0.914
4.732SerPhe: 4.732 ± 0.965
3.975SerGly: 3.975 ± 0.676
1.514SerHis: 1.514 ± 0.54
8.139SerIle: 8.139 ± 2.13
5.679SerLys: 5.679 ± 1.343
10.6SerLeu: 10.6 ± 1.686
0.568SerMet: 0.568 ± 0.24
5.679SerAsn: 5.679 ± 1.158
2.65SerPro: 2.65 ± 0.857
3.407SerGln: 3.407 ± 0.552
3.029SerArg: 3.029 ± 0.839
5.868SerSer: 5.868 ± 1.31
3.786SerThr: 3.786 ± 0.659
3.407SerVal: 3.407 ± 0.795
0.568SerTrp: 0.568 ± 0.24
3.218SerTyr: 3.218 ± 0.667
0.0SerXaa: 0.0 ± 0.0
Thr
3.407ThrAla: 3.407 ± 0.734
0.946ThrCys: 0.946 ± 0.332
3.029ThrAsp: 3.029 ± 0.856
2.082ThrGlu: 2.082 ± 0.583
4.543ThrPhe: 4.543 ± 0.878
1.893ThrGly: 1.893 ± 0.66
1.893ThrHis: 1.893 ± 0.401
6.057ThrIle: 6.057 ± 0.952
3.975ThrLys: 3.975 ± 1.007
6.057ThrLeu: 6.057 ± 0.832
0.946ThrMet: 0.946 ± 0.303
3.407ThrAsn: 3.407 ± 0.791
3.596ThrPro: 3.596 ± 0.918
3.029ThrGln: 3.029 ± 1.144
2.271ThrArg: 2.271 ± 0.43
4.164ThrSer: 4.164 ± 0.894
4.921ThrThr: 4.921 ± 0.875
2.839ThrVal: 2.839 ± 0.711
0.379ThrTrp: 0.379 ± 0.405
3.029ThrTyr: 3.029 ± 0.56
0.0ThrXaa: 0.0 ± 0.0
Val
3.407ValAla: 3.407 ± 0.814
0.946ValCys: 0.946 ± 0.23
5.3ValAsp: 5.3 ± 1.087
3.218ValGlu: 3.218 ± 0.743
2.461ValPhe: 2.461 ± 0.518
3.218ValGly: 3.218 ± 0.812
0.757ValHis: 0.757 ± 0.295
3.975ValIle: 3.975 ± 0.876
4.354ValLys: 4.354 ± 0.835
5.679ValLeu: 5.679 ± 0.738
1.136ValMet: 1.136 ± 0.41
4.354ValAsn: 4.354 ± 1.028
2.271ValPro: 2.271 ± 0.595
2.65ValGln: 2.65 ± 0.728
4.543ValArg: 4.543 ± 1.149
4.164ValSer: 4.164 ± 0.928
2.839ValThr: 2.839 ± 0.833
3.218ValVal: 3.218 ± 1.016
0.189ValTrp: 0.189 ± 0.192
2.65ValTyr: 2.65 ± 0.531
0.0ValXaa: 0.0 ± 0.0
Trp
0.189TrpAla: 0.189 ± 0.207
0.0TrpCys: 0.0 ± 0.0
0.379TrpAsp: 0.379 ± 0.209
0.379TrpGlu: 0.379 ± 0.237
0.757TrpPhe: 0.757 ± 0.344
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.379TrpIle: 0.379 ± 0.489
0.568TrpLys: 0.568 ± 0.435
1.325TrpLeu: 1.325 ± 0.475
0.568TrpMet: 0.568 ± 0.259
0.189TrpAsn: 0.189 ± 0.23
0.379TrpPro: 0.379 ± 0.334
0.189TrpGln: 0.189 ± 0.118
0.379TrpArg: 0.379 ± 0.295
0.189TrpSer: 0.189 ± 0.118
0.757TrpThr: 0.757 ± 0.416
1.136TrpVal: 1.136 ± 0.301
0.0TrpTrp: 0.0 ± 0.0
0.379TrpTyr: 0.379 ± 0.237
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.461TyrAla: 2.461 ± 0.51
1.136TyrCys: 1.136 ± 0.484
1.704TyrAsp: 1.704 ± 0.632
1.514TyrGlu: 1.514 ± 0.784
2.271TyrPhe: 2.271 ± 0.745
1.704TyrGly: 1.704 ± 0.544
1.704TyrHis: 1.704 ± 0.892
3.029TyrIle: 3.029 ± 0.829
1.893TyrLys: 1.893 ± 0.537
5.3TyrLeu: 5.3 ± 0.804
1.325TyrMet: 1.325 ± 0.623
3.029TyrAsn: 3.029 ± 0.609
1.136TyrPro: 1.136 ± 0.469
0.946TyrGln: 0.946 ± 0.394
2.271TyrArg: 2.271 ± 0.405
5.111TyrSer: 5.111 ± 0.618
2.461TyrThr: 2.461 ± 0.592
2.65TyrVal: 2.65 ± 0.465
0.0TyrTrp: 0.0 ± 0.0
2.271TyrTyr: 2.271 ± 1.095
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (5284 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski