Amino acid dipepetide frequency for Hubei picorna-like virus 45

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.438AlaAla: 4.438 ± 0.0
0.888AlaCys: 0.888 ± 0.0
2.367AlaAsp: 2.367 ± 0.0
4.438AlaGlu: 4.438 ± 0.0
4.142AlaPhe: 4.142 ± 0.0
4.438AlaGly: 4.438 ± 0.0
1.479AlaHis: 1.479 ± 0.0
4.734AlaIle: 4.734 ± 0.0
3.846AlaLys: 3.846 ± 0.0
6.213AlaLeu: 6.213 ± 0.0
2.071AlaMet: 2.071 ± 0.0
2.663AlaAsn: 2.663 ± 0.0
3.254AlaPro: 3.254 ± 0.0
3.254AlaGln: 3.254 ± 0.0
4.734AlaArg: 4.734 ± 0.0
3.254AlaSer: 3.254 ± 0.0
3.254AlaThr: 3.254 ± 0.0
4.142AlaVal: 4.142 ± 0.0
0.592AlaTrp: 0.592 ± 0.0
2.367AlaTyr: 2.367 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.183CysAla: 1.183 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.888CysAsp: 0.888 ± 0.0
1.183CysGlu: 1.183 ± 0.0
1.479CysPhe: 1.479 ± 0.0
1.183CysGly: 1.183 ± 0.0
0.296CysHis: 0.296 ± 0.0
1.183CysIle: 1.183 ± 0.0
1.479CysLys: 1.479 ± 0.0
2.663CysLeu: 2.663 ± 0.0
0.296CysMet: 0.296 ± 0.0
0.296CysAsn: 0.296 ± 0.0
1.479CysPro: 1.479 ± 0.0
0.888CysGln: 0.888 ± 0.0
1.479CysArg: 1.479 ± 0.0
0.888CysSer: 0.888 ± 0.0
0.888CysThr: 0.888 ± 0.0
2.367CysVal: 2.367 ± 0.0
0.888CysTrp: 0.888 ± 0.0
0.888CysTyr: 0.888 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.071AspAla: 2.071 ± 0.0
1.775AspCys: 1.775 ± 0.0
3.55AspAsp: 3.55 ± 0.0
6.805AspGlu: 6.805 ± 0.0
3.846AspPhe: 3.846 ± 0.0
3.55AspGly: 3.55 ± 0.0
0.296AspHis: 0.296 ± 0.0
3.254AspIle: 3.254 ± 0.0
4.142AspLys: 4.142 ± 0.0
5.621AspLeu: 5.621 ± 0.0
1.183AspMet: 1.183 ± 0.0
2.367AspAsn: 2.367 ± 0.0
3.254AspPro: 3.254 ± 0.0
1.479AspGln: 1.479 ± 0.0
3.254AspArg: 3.254 ± 0.0
4.142AspSer: 4.142 ± 0.0
2.959AspThr: 2.959 ± 0.0
2.959AspVal: 2.959 ± 0.0
2.367AspTrp: 2.367 ± 0.0
1.479AspTyr: 1.479 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.438GluAla: 4.438 ± 0.0
2.071GluCys: 2.071 ± 0.0
4.142GluAsp: 4.142 ± 0.0
7.988GluGlu: 7.988 ± 0.0
3.846GluPhe: 3.846 ± 0.0
4.734GluGly: 4.734 ± 0.0
1.183GluHis: 1.183 ± 0.0
4.734GluIle: 4.734 ± 0.0
2.959GluLys: 2.959 ± 0.0
4.438GluLeu: 4.438 ± 0.0
2.663GluMet: 2.663 ± 0.0
2.367GluAsn: 2.367 ± 0.0
3.846GluPro: 3.846 ± 0.0
3.254GluGln: 3.254 ± 0.0
2.959GluArg: 2.959 ± 0.0
5.325GluSer: 5.325 ± 0.0
1.479GluThr: 1.479 ± 0.0
4.142GluVal: 4.142 ± 0.0
0.592GluTrp: 0.592 ± 0.0
2.367GluTyr: 2.367 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.959PheAla: 2.959 ± 0.0
1.183PheCys: 1.183 ± 0.0
4.438PheAsp: 4.438 ± 0.0
2.663PheGlu: 2.663 ± 0.0
2.959PhePhe: 2.959 ± 0.0
2.959PheGly: 2.959 ± 0.0
1.479PheHis: 1.479 ± 0.0
1.479PheIle: 1.479 ± 0.0
2.959PheLys: 2.959 ± 0.0
3.846PheLeu: 3.846 ± 0.0
1.479PheMet: 1.479 ± 0.0
2.959PheAsn: 2.959 ± 0.0
1.183PhePro: 1.183 ± 0.0
2.071PheGln: 2.071 ± 0.0
3.846PheArg: 3.846 ± 0.0
3.254PheSer: 3.254 ± 0.0
4.142PheThr: 4.142 ± 0.0
3.846PheVal: 3.846 ± 0.0
0.888PheTrp: 0.888 ± 0.0
2.071PheTyr: 2.071 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.509GlyAla: 6.509 ± 0.0
0.888GlyCys: 0.888 ± 0.0
2.663GlyAsp: 2.663 ± 0.0
2.959GlyGlu: 2.959 ± 0.0
3.55GlyPhe: 3.55 ± 0.0
2.663GlyGly: 2.663 ± 0.0
0.592GlyHis: 0.592 ± 0.0
4.142GlyIle: 4.142 ± 0.0
4.438GlyLys: 4.438 ± 0.0
3.846GlyLeu: 3.846 ± 0.0
0.888GlyMet: 0.888 ± 0.0
2.959GlyAsn: 2.959 ± 0.0
1.775GlyPro: 1.775 ± 0.0
1.479GlyGln: 1.479 ± 0.0
2.367GlyArg: 2.367 ± 0.0
3.254GlySer: 3.254 ± 0.0
2.959GlyThr: 2.959 ± 0.0
3.846GlyVal: 3.846 ± 0.0
0.592GlyTrp: 0.592 ± 0.0
2.071GlyTyr: 2.071 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.592HisCys: 0.592 ± 0.0
1.183HisAsp: 1.183 ± 0.0
0.888HisGlu: 0.888 ± 0.0
1.479HisPhe: 1.479 ± 0.0
0.888HisGly: 0.888 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.888HisIle: 0.888 ± 0.0
0.296HisLys: 0.296 ± 0.0
2.663HisLeu: 2.663 ± 0.0
0.296HisMet: 0.296 ± 0.0
1.183HisAsn: 1.183 ± 0.0
1.183HisPro: 1.183 ± 0.0
1.479HisGln: 1.479 ± 0.0
1.775HisArg: 1.775 ± 0.0
1.183HisSer: 1.183 ± 0.0
0.592HisThr: 0.592 ± 0.0
0.888HisVal: 0.888 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.296HisTyr: 0.296 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.734IleAla: 4.734 ± 0.0
1.479IleCys: 1.479 ± 0.0
3.846IleAsp: 3.846 ± 0.0
5.03IleGlu: 5.03 ± 0.0
3.55IlePhe: 3.55 ± 0.0
2.071IleGly: 2.071 ± 0.0
0.888IleHis: 0.888 ± 0.0
2.367IleIle: 2.367 ± 0.0
3.254IleLys: 3.254 ± 0.0
4.438IleLeu: 4.438 ± 0.0
1.183IleMet: 1.183 ± 0.0
1.775IleAsn: 1.775 ± 0.0
3.846IlePro: 3.846 ± 0.0
2.959IleGln: 2.959 ± 0.0
1.183IleArg: 1.183 ± 0.0
3.846IleSer: 3.846 ± 0.0
2.959IleThr: 2.959 ± 0.0
3.846IleVal: 3.846 ± 0.0
0.296IleTrp: 0.296 ± 0.0
3.254IleTyr: 3.254 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.142LysAla: 4.142 ± 0.0
1.775LysCys: 1.775 ± 0.0
2.959LysAsp: 2.959 ± 0.0
2.367LysGlu: 2.367 ± 0.0
2.367LysPhe: 2.367 ± 0.0
2.071LysGly: 2.071 ± 0.0
0.888LysHis: 0.888 ± 0.0
2.959LysIle: 2.959 ± 0.0
2.663LysLys: 2.663 ± 0.0
4.734LysLeu: 4.734 ± 0.0
1.775LysMet: 1.775 ± 0.0
3.55LysAsn: 3.55 ± 0.0
3.846LysPro: 3.846 ± 0.0
0.888LysGln: 0.888 ± 0.0
3.254LysArg: 3.254 ± 0.0
3.254LysSer: 3.254 ± 0.0
2.959LysThr: 2.959 ± 0.0
3.846LysVal: 3.846 ± 0.0
0.888LysTrp: 0.888 ± 0.0
2.663LysTyr: 2.663 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.621LeuAla: 5.621 ± 0.0
1.775LeuCys: 1.775 ± 0.0
6.805LeuAsp: 6.805 ± 0.0
5.621LeuGlu: 5.621 ± 0.0
4.734LeuPhe: 4.734 ± 0.0
3.55LeuGly: 3.55 ± 0.0
2.663LeuHis: 2.663 ± 0.0
5.03LeuIle: 5.03 ± 0.0
5.917LeuLys: 5.917 ± 0.0
5.917LeuLeu: 5.917 ± 0.0
1.775LeuMet: 1.775 ± 0.0
5.621LeuAsn: 5.621 ± 0.0
6.213LeuPro: 6.213 ± 0.0
3.254LeuGln: 3.254 ± 0.0
5.03LeuArg: 5.03 ± 0.0
5.621LeuSer: 5.621 ± 0.0
6.213LeuThr: 6.213 ± 0.0
3.254LeuVal: 3.254 ± 0.0
1.479LeuTrp: 1.479 ± 0.0
2.959LeuTyr: 2.959 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.775MetAla: 1.775 ± 0.0
2.071MetCys: 2.071 ± 0.0
2.367MetAsp: 2.367 ± 0.0
1.479MetGlu: 1.479 ± 0.0
1.183MetPhe: 1.183 ± 0.0
1.775MetGly: 1.775 ± 0.0
0.888MetHis: 0.888 ± 0.0
0.592MetIle: 0.592 ± 0.0
1.479MetLys: 1.479 ± 0.0
1.775MetLeu: 1.775 ± 0.0
0.592MetMet: 0.592 ± 0.0
2.071MetAsn: 2.071 ± 0.0
0.888MetPro: 0.888 ± 0.0
1.183MetGln: 1.183 ± 0.0
1.183MetArg: 1.183 ± 0.0
2.071MetSer: 2.071 ± 0.0
2.663MetThr: 2.663 ± 0.0
1.775MetVal: 1.775 ± 0.0
0.296MetTrp: 0.296 ± 0.0
0.296MetTyr: 0.296 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.438AsnAla: 4.438 ± 0.0
1.183AsnCys: 1.183 ± 0.0
2.663AsnAsp: 2.663 ± 0.0
2.367AsnGlu: 2.367 ± 0.0
3.846AsnPhe: 3.846 ± 0.0
1.479AsnGly: 1.479 ± 0.0
0.296AsnHis: 0.296 ± 0.0
1.479AsnIle: 1.479 ± 0.0
2.959AsnLys: 2.959 ± 0.0
7.988AsnLeu: 7.988 ± 0.0
2.071AsnMet: 2.071 ± 0.0
2.071AsnAsn: 2.071 ± 0.0
3.254AsnPro: 3.254 ± 0.0
1.479AsnGln: 1.479 ± 0.0
3.55AsnArg: 3.55 ± 0.0
1.183AsnSer: 1.183 ± 0.0
2.071AsnThr: 2.071 ± 0.0
2.367AsnVal: 2.367 ± 0.0
0.888AsnTrp: 0.888 ± 0.0
0.888AsnTyr: 0.888 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.846ProAla: 3.846 ± 0.0
0.0ProCys: 0.0 ± 0.0
1.775ProAsp: 1.775 ± 0.0
3.846ProGlu: 3.846 ± 0.0
2.959ProPhe: 2.959 ± 0.0
2.663ProGly: 2.663 ± 0.0
0.592ProHis: 0.592 ± 0.0
4.142ProIle: 4.142 ± 0.0
3.846ProLys: 3.846 ± 0.0
4.734ProLeu: 4.734 ± 0.0
2.663ProMet: 2.663 ± 0.0
2.367ProAsn: 2.367 ± 0.0
4.142ProPro: 4.142 ± 0.0
1.183ProGln: 1.183 ± 0.0
3.254ProArg: 3.254 ± 0.0
2.367ProSer: 2.367 ± 0.0
4.142ProThr: 4.142 ± 0.0
4.438ProVal: 4.438 ± 0.0
2.071ProTrp: 2.071 ± 0.0
2.367ProTyr: 2.367 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.663GlnAla: 2.663 ± 0.0
0.888GlnCys: 0.888 ± 0.0
1.183GlnAsp: 1.183 ± 0.0
2.663GlnGlu: 2.663 ± 0.0
1.183GlnPhe: 1.183 ± 0.0
4.734GlnGly: 4.734 ± 0.0
0.296GlnHis: 0.296 ± 0.0
1.775GlnIle: 1.775 ± 0.0
1.775GlnLys: 1.775 ± 0.0
2.959GlnLeu: 2.959 ± 0.0
2.071GlnMet: 2.071 ± 0.0
3.254GlnAsn: 3.254 ± 0.0
1.775GlnPro: 1.775 ± 0.0
0.296GlnGln: 0.296 ± 0.0
0.888GlnArg: 0.888 ± 0.0
1.479GlnSer: 1.479 ± 0.0
1.479GlnThr: 1.479 ± 0.0
1.775GlnVal: 1.775 ± 0.0
0.888GlnTrp: 0.888 ± 0.0
1.479GlnTyr: 1.479 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.254ArgAla: 3.254 ± 0.0
1.479ArgCys: 1.479 ± 0.0
2.367ArgAsp: 2.367 ± 0.0
4.438ArgGlu: 4.438 ± 0.0
1.775ArgPhe: 1.775 ± 0.0
2.367ArgGly: 2.367 ± 0.0
0.592ArgHis: 0.592 ± 0.0
5.621ArgIle: 5.621 ± 0.0
4.142ArgLys: 4.142 ± 0.0
6.213ArgLeu: 6.213 ± 0.0
1.775ArgMet: 1.775 ± 0.0
1.479ArgAsn: 1.479 ± 0.0
4.142ArgPro: 4.142 ± 0.0
1.183ArgGln: 1.183 ± 0.0
3.254ArgArg: 3.254 ± 0.0
3.55ArgSer: 3.55 ± 0.0
1.479ArgThr: 1.479 ± 0.0
3.846ArgVal: 3.846 ± 0.0
1.183ArgTrp: 1.183 ± 0.0
2.071ArgTyr: 2.071 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
1.479SerAla: 1.479 ± 0.0
0.888SerCys: 0.888 ± 0.0
4.142SerAsp: 4.142 ± 0.0
4.438SerGlu: 4.438 ± 0.0
1.775SerPhe: 1.775 ± 0.0
3.254SerGly: 3.254 ± 0.0
2.663SerHis: 2.663 ± 0.0
2.959SerIle: 2.959 ± 0.0
1.479SerLys: 1.479 ± 0.0
5.917SerLeu: 5.917 ± 0.0
1.775SerMet: 1.775 ± 0.0
1.775SerAsn: 1.775 ± 0.0
3.846SerPro: 3.846 ± 0.0
3.254SerGln: 3.254 ± 0.0
3.254SerArg: 3.254 ± 0.0
3.254SerSer: 3.254 ± 0.0
5.03SerThr: 5.03 ± 0.0
6.213SerVal: 6.213 ± 0.0
0.296SerTrp: 0.296 ± 0.0
2.663SerTyr: 2.663 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.846ThrAla: 3.846 ± 0.0
0.888ThrCys: 0.888 ± 0.0
3.254ThrAsp: 3.254 ± 0.0
2.663ThrGlu: 2.663 ± 0.0
2.367ThrPhe: 2.367 ± 0.0
3.55ThrGly: 3.55 ± 0.0
1.183ThrHis: 1.183 ± 0.0
2.959ThrIle: 2.959 ± 0.0
2.663ThrLys: 2.663 ± 0.0
6.213ThrLeu: 6.213 ± 0.0
0.888ThrMet: 0.888 ± 0.0
4.142ThrAsn: 4.142 ± 0.0
3.254ThrPro: 3.254 ± 0.0
1.775ThrGln: 1.775 ± 0.0
2.367ThrArg: 2.367 ± 0.0
3.254ThrSer: 3.254 ± 0.0
4.142ThrThr: 4.142 ± 0.0
4.438ThrVal: 4.438 ± 0.0
0.888ThrTrp: 0.888 ± 0.0
1.775ThrTyr: 1.775 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.142ValAla: 4.142 ± 0.0
1.775ValCys: 1.775 ± 0.0
6.213ValAsp: 6.213 ± 0.0
3.55ValGlu: 3.55 ± 0.0
3.254ValPhe: 3.254 ± 0.0
5.325ValGly: 5.325 ± 0.0
0.592ValHis: 0.592 ± 0.0
3.254ValIle: 3.254 ± 0.0
2.071ValLys: 2.071 ± 0.0
5.03ValLeu: 5.03 ± 0.0
2.071ValMet: 2.071 ± 0.0
2.663ValAsn: 2.663 ± 0.0
3.55ValPro: 3.55 ± 0.0
2.367ValGln: 2.367 ± 0.0
3.55ValArg: 3.55 ± 0.0
5.621ValSer: 5.621 ± 0.0
3.254ValThr: 3.254 ± 0.0
1.775ValVal: 1.775 ± 0.0
0.0ValTrp: 0.0 ± 0.0
2.071ValTyr: 2.071 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.367TrpAla: 2.367 ± 0.0
0.296TrpCys: 0.296 ± 0.0
0.592TrpAsp: 0.592 ± 0.0
0.888TrpGlu: 0.888 ± 0.0
0.296TrpPhe: 0.296 ± 0.0
0.296TrpGly: 0.296 ± 0.0
0.296TrpHis: 0.296 ± 0.0
1.479TrpIle: 1.479 ± 0.0
0.296TrpLys: 0.296 ± 0.0
0.592TrpLeu: 0.592 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.888TrpAsn: 0.888 ± 0.0
0.592TrpPro: 0.592 ± 0.0
0.592TrpGln: 0.592 ± 0.0
2.071TrpArg: 2.071 ± 0.0
1.775TrpSer: 1.775 ± 0.0
0.888TrpThr: 0.888 ± 0.0
0.592TrpVal: 0.592 ± 0.0
0.296TrpTrp: 0.296 ± 0.0
0.888TrpTyr: 0.888 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.663TyrAla: 2.663 ± 0.0
0.0TyrCys: 0.0 ± 0.0
3.254TyrAsp: 3.254 ± 0.0
3.254TyrGlu: 3.254 ± 0.0
2.071TyrPhe: 2.071 ± 0.0
0.888TyrGly: 0.888 ± 0.0
0.592TyrHis: 0.592 ± 0.0
1.775TyrIle: 1.775 ± 0.0
1.183TyrLys: 1.183 ± 0.0
3.254TyrLeu: 3.254 ± 0.0
0.592TyrMet: 0.592 ± 0.0
2.071TyrAsn: 2.071 ± 0.0
2.071TyrPro: 2.071 ± 0.0
1.183TyrGln: 1.183 ± 0.0
2.959TyrArg: 2.959 ± 0.0
1.775TyrSer: 1.775 ± 0.0
2.959TyrThr: 2.959 ± 0.0
1.775TyrVal: 1.775 ± 0.0
0.592TyrTrp: 0.592 ± 0.0
1.183TyrTyr: 1.183 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3381 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski