Amino acid dipepetide frequency for Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
20.662AlaAla: 20.662 ± 0.212
1.383AlaCys: 1.383 ± 0.039
6.516AlaAsp: 6.516 ± 0.096
6.716AlaGlu: 6.716 ± 0.092
4.077AlaPhe: 4.077 ± 0.06
12.815AlaGly: 12.815 ± 0.144
2.725AlaHis: 2.725 ± 0.053
4.682AlaIle: 4.682 ± 0.074
3.22AlaLys: 3.22 ± 0.067
15.335AlaLeu: 15.335 ± 0.172
3.447AlaMet: 3.447 ± 0.051
2.631AlaAsn: 2.631 ± 0.094
7.048AlaPro: 7.048 ± 0.105
6.428AlaGln: 6.428 ± 0.083
10.844AlaArg: 10.844 ± 0.137
6.606AlaSer: 6.606 ± 0.073
6.01AlaThr: 6.01 ± 0.087
9.977AlaVal: 9.977 ± 0.141
2.208AlaTrp: 2.208 ± 0.05
2.434AlaTyr: 2.434 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
1.184CysAla: 1.184 ± 0.033
0.114CysCys: 0.114 ± 0.009
0.492CysAsp: 0.492 ± 0.021
0.518CysGlu: 0.518 ± 0.021
0.259CysPhe: 0.259 ± 0.015
1.0CysGly: 1.0 ± 0.029
0.278CysHis: 0.278 ± 0.017
0.376CysIle: 0.376 ± 0.017
0.209CysLys: 0.209 ± 0.012
0.768CysLeu: 0.768 ± 0.026
0.19CysMet: 0.19 ± 0.013
0.206CysAsn: 0.206 ± 0.012
0.482CysPro: 0.482 ± 0.021
0.26CysGln: 0.26 ± 0.015
0.684CysArg: 0.684 ± 0.025
0.491CysSer: 0.491 ± 0.021
0.443CysThr: 0.443 ± 0.021
0.711CysVal: 0.711 ± 0.028
0.124CysTrp: 0.124 ± 0.009
0.186CysTyr: 0.186 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
6.822AspAla: 6.822 ± 0.082
0.403AspCys: 0.403 ± 0.02
2.379AspAsp: 2.379 ± 0.06
3.026AspGlu: 3.026 ± 0.054
1.925AspPhe: 1.925 ± 0.041
4.639AspGly: 4.639 ± 0.105
1.036AspHis: 1.036 ± 0.028
2.167AspIle: 2.167 ± 0.041
1.544AspLys: 1.544 ± 0.039
5.126AspLeu: 5.126 ± 0.073
1.112AspMet: 1.112 ± 0.03
1.123AspAsn: 1.123 ± 0.035
2.981AspPro: 2.981 ± 0.057
1.533AspGln: 1.533 ± 0.041
3.527AspArg: 3.527 ± 0.053
2.042AspSer: 2.042 ± 0.052
2.447AspThr: 2.447 ± 0.115
3.727AspVal: 3.727 ± 0.065
0.912AspTrp: 0.912 ± 0.028
1.234AspTyr: 1.234 ± 0.038
0.0AspXaa: 0.0 ± 0.0
Glu
7.165GluAla: 7.165 ± 0.091
0.375GluCys: 0.375 ± 0.017
2.261GluAsp: 2.261 ± 0.055
2.628GluGlu: 2.628 ± 0.051
1.829GluPhe: 1.829 ± 0.044
3.999GluGly: 3.999 ± 0.068
1.3GluHis: 1.3 ± 0.035
2.415GluIle: 2.415 ± 0.049
1.656GluLys: 1.656 ± 0.043
6.217GluLeu: 6.217 ± 0.087
1.255GluMet: 1.255 ± 0.035
1.144GluAsn: 1.144 ± 0.04
2.909GluPro: 2.909 ± 0.052
2.635GluGln: 2.635 ± 0.054
5.047GluArg: 5.047 ± 0.075
2.232GluSer: 2.232 ± 0.04
2.261GluThr: 2.261 ± 0.053
4.363GluVal: 4.363 ± 0.073
0.732GluTrp: 0.732 ± 0.022
1.015GluTyr: 1.015 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
4.189PheAla: 4.189 ± 0.063
0.374PheCys: 0.374 ± 0.017
2.352PheAsp: 2.352 ± 0.043
2.035PheGlu: 2.035 ± 0.036
1.319PhePhe: 1.319 ± 0.036
3.379PheGly: 3.379 ± 0.055
0.734PheHis: 0.734 ± 0.027
1.318PheIle: 1.318 ± 0.036
0.961PheLys: 0.961 ± 0.032
3.006PheLeu: 3.006 ± 0.059
0.744PheMet: 0.744 ± 0.027
0.995PheAsn: 0.995 ± 0.029
1.511PhePro: 1.511 ± 0.034
1.092PheGln: 1.092 ± 0.033
2.032PheArg: 2.032 ± 0.048
1.944PheSer: 1.944 ± 0.04
1.827PheThr: 1.827 ± 0.057
2.651PheVal: 2.651 ± 0.053
0.505PheTrp: 0.505 ± 0.021
0.793PheTyr: 0.793 ± 0.024
0.0PheXaa: 0.0 ± 0.0
Gly
10.246GlyAla: 10.246 ± 0.131
0.939GlyCys: 0.939 ± 0.028
3.917GlyAsp: 3.917 ± 0.073
4.881GlyGlu: 4.881 ± 0.078
3.373GlyPhe: 3.373 ± 0.057
8.179GlyGly: 8.179 ± 0.156
2.029GlyHis: 2.029 ± 0.044
3.824GlyIle: 3.824 ± 0.062
2.93GlyLys: 2.93 ± 0.058
9.63GlyLeu: 9.63 ± 0.113
2.271GlyMet: 2.271 ± 0.048
2.101GlyAsn: 2.101 ± 0.09
3.679GlyPro: 3.679 ± 0.069
3.677GlyGln: 3.677 ± 0.069
7.01GlyArg: 7.01 ± 0.091
4.749GlySer: 4.749 ± 0.08
4.693GlyThr: 4.693 ± 0.104
6.638GlyVal: 6.638 ± 0.082
1.612GlyTrp: 1.612 ± 0.043
2.251GlyTyr: 2.251 ± 0.043
0.0GlyXaa: 0.0 ± 0.0
His
2.818HisAla: 2.818 ± 0.054
0.266HisCys: 0.266 ± 0.014
1.115HisAsp: 1.115 ± 0.034
1.212HisGlu: 1.212 ± 0.031
0.848HisPhe: 0.848 ± 0.027
2.28HisGly: 2.28 ± 0.05
0.643HisHis: 0.643 ± 0.024
0.814HisIle: 0.814 ± 0.026
0.555HisLys: 0.555 ± 0.023
2.314HisLeu: 2.314 ± 0.056
0.465HisMet: 0.465 ± 0.02
0.457HisAsn: 0.457 ± 0.02
1.553HisPro: 1.553 ± 0.035
0.778HisGln: 0.778 ± 0.024
1.692HisArg: 1.692 ± 0.039
0.928HisSer: 0.928 ± 0.031
1.003HisThr: 1.003 ± 0.034
1.535HisVal: 1.535 ± 0.039
0.435HisTrp: 0.435 ± 0.021
0.571HisTyr: 0.571 ± 0.026
0.0HisXaa: 0.0 ± 0.0
Ile
5.761IleAla: 5.761 ± 0.069
0.361IleCys: 0.361 ± 0.018
2.507IleAsp: 2.507 ± 0.051
2.699IleGlu: 2.699 ± 0.051
1.081IlePhe: 1.081 ± 0.036
3.682IleGly: 3.682 ± 0.063
0.805IleHis: 0.805 ± 0.025
1.199IleIle: 1.199 ± 0.042
1.15IleLys: 1.15 ± 0.036
2.992IleLeu: 2.992 ± 0.056
0.629IleMet: 0.629 ± 0.027
1.216IleAsn: 1.216 ± 0.038
1.845IlePro: 1.845 ± 0.041
1.146IleGln: 1.146 ± 0.031
2.581IleArg: 2.581 ± 0.048
1.89IleSer: 1.89 ± 0.044
2.08IleThr: 2.08 ± 0.056
3.151IleVal: 3.151 ± 0.055
0.374IleTrp: 0.374 ± 0.019
0.787IleTyr: 0.787 ± 0.024
0.0IleXaa: 0.0 ± 0.0
Lys
3.702LysAla: 3.702 ± 0.071
0.138LysCys: 0.138 ± 0.012
1.472LysAsp: 1.472 ± 0.042
1.354LysGlu: 1.354 ± 0.045
0.807LysPhe: 0.807 ± 0.028
2.182LysGly: 2.182 ± 0.049
0.551LysHis: 0.551 ± 0.022
1.172LysIle: 1.172 ± 0.037
1.169LysLys: 1.169 ± 0.049
3.145LysLeu: 3.145 ± 0.063
0.655LysMet: 0.655 ± 0.025
0.773LysAsn: 0.773 ± 0.026
1.919LysPro: 1.919 ± 0.053
1.037LysGln: 1.037 ± 0.037
1.877LysArg: 1.877 ± 0.047
1.427LysSer: 1.427 ± 0.039
1.563LysThr: 1.563 ± 0.037
2.254LysVal: 2.254 ± 0.046
0.309LysTrp: 0.309 ± 0.014
0.583LysTyr: 0.583 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
16.776LeuAla: 16.776 ± 0.163
0.967LeuCys: 0.967 ± 0.03
5.552LeuAsp: 5.552 ± 0.062
5.511LeuGlu: 5.511 ± 0.072
3.281LeuPhe: 3.281 ± 0.064
9.205LeuGly: 9.205 ± 0.121
2.467LeuHis: 2.467 ± 0.057
3.56LeuIle: 3.56 ± 0.063
3.239LeuLys: 3.239 ± 0.059
11.834LeuLeu: 11.834 ± 0.156
2.454LeuMet: 2.454 ± 0.057
2.37LeuAsn: 2.37 ± 0.05
6.506LeuPro: 6.506 ± 0.091
4.624LeuGln: 4.624 ± 0.071
8.645LeuArg: 8.645 ± 0.118
5.338LeuSer: 5.338 ± 0.069
4.915LeuThr: 4.915 ± 0.089
8.356LeuVal: 8.356 ± 0.086
1.449LeuTrp: 1.449 ± 0.042
1.965LeuTyr: 1.965 ± 0.042
0.0LeuXaa: 0.0 ± 0.0
Met
3.119MetAla: 3.119 ± 0.06
0.156MetCys: 0.156 ± 0.013
1.204MetAsp: 1.204 ± 0.03
1.114MetGlu: 1.114 ± 0.031
0.675MetPhe: 0.675 ± 0.029
1.831MetGly: 1.831 ± 0.043
0.483MetHis: 0.483 ± 0.017
0.797MetIle: 0.797 ± 0.025
0.959MetLys: 0.959 ± 0.028
2.482MetLeu: 2.482 ± 0.054
0.515MetMet: 0.515 ± 0.023
0.829MetAsn: 0.829 ± 0.026
1.44MetPro: 1.44 ± 0.034
0.964MetGln: 0.964 ± 0.029
1.821MetArg: 1.821 ± 0.037
1.374MetSer: 1.374 ± 0.034
1.376MetThr: 1.376 ± 0.036
1.659MetVal: 1.659 ± 0.041
0.186MetTrp: 0.186 ± 0.013
0.368MetTyr: 0.368 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
2.992AsnAla: 2.992 ± 0.073
0.225AsnCys: 0.225 ± 0.014
1.211AsnAsp: 1.211 ± 0.076
1.072AsnGlu: 1.072 ± 0.032
0.843AsnPhe: 0.843 ± 0.027
2.089AsnGly: 2.089 ± 0.104
0.466AsnHis: 0.466 ± 0.02
1.045AsnIle: 1.045 ± 0.03
0.708AsnLys: 0.708 ± 0.025
2.423AsnLeu: 2.423 ± 0.057
0.503AsnMet: 0.503 ± 0.02
0.687AsnAsn: 0.687 ± 0.028
1.74AsnPro: 1.74 ± 0.034
0.821AsnGln: 0.821 ± 0.026
1.634AsnArg: 1.634 ± 0.038
0.995AsnSer: 0.995 ± 0.032
1.215AsnThr: 1.215 ± 0.054
1.806AsnVal: 1.806 ± 0.063
0.346AsnTrp: 0.346 ± 0.015
0.606AsnTyr: 0.606 ± 0.029
0.0AsnXaa: 0.0 ± 0.0
Pro
8.623ProAla: 8.623 ± 0.117
0.388ProCys: 0.388 ± 0.017
3.013ProAsp: 3.013 ± 0.061
3.317ProGlu: 3.317 ± 0.065
1.817ProPhe: 1.817 ± 0.04
5.617ProGly: 5.617 ± 0.081
1.2ProHis: 1.2 ± 0.033
1.664ProIle: 1.664 ± 0.038
1.197ProLys: 1.197 ± 0.035
5.565ProLeu: 5.565 ± 0.082
1.289ProMet: 1.289 ± 0.034
1.154ProAsn: 1.154 ± 0.032
3.295ProPro: 3.295 ± 0.067
2.711ProGln: 2.711 ± 0.053
3.803ProArg: 3.803 ± 0.074
2.664ProSer: 2.664 ± 0.046
2.402ProThr: 2.402 ± 0.039
4.64ProVal: 4.64 ± 0.066
0.86ProTrp: 0.86 ± 0.026
1.144ProTyr: 1.144 ± 0.029
0.0ProXaa: 0.0 ± 0.0
Gln
6.81GlnAla: 6.81 ± 0.08
0.283GlnCys: 0.283 ± 0.015
1.783GlnAsp: 1.783 ± 0.043
1.943GlnGlu: 1.943 ± 0.041
1.105GlnPhe: 1.105 ± 0.032
3.56GlnGly: 3.56 ± 0.055
0.894GlnHis: 0.894 ± 0.025
1.364GlnIle: 1.364 ± 0.04
0.999GlnLys: 0.999 ± 0.032
4.524GlnLeu: 4.524 ± 0.067
0.9GlnMet: 0.9 ± 0.028
0.687GlnAsn: 0.687 ± 0.023
2.811GlnPro: 2.811 ± 0.052
1.986GlnGln: 1.986 ± 0.055
3.623GlnArg: 3.623 ± 0.06
1.652GlnSer: 1.652 ± 0.034
1.563GlnThr: 1.563 ± 0.037
3.516GlnVal: 3.516 ± 0.059
0.643GlnTrp: 0.643 ± 0.024
0.663GlnTyr: 0.663 ± 0.023
0.0GlnXaa: 0.0 ± 0.0
Arg
8.8ArgAla: 8.8 ± 0.095
0.649ArgCys: 0.649 ± 0.024
3.656ArgAsp: 3.656 ± 0.06
4.971ArgGlu: 4.971 ± 0.075
3.001ArgPhe: 3.001 ± 0.049
5.533ArgGly: 5.533 ± 0.083
2.105ArgHis: 2.105 ± 0.043
3.512ArgIle: 3.512 ± 0.061
2.121ArgLys: 2.121 ± 0.04
9.161ArgLeu: 9.161 ± 0.131
2.11ArgMet: 2.11 ± 0.041
1.77ArgAsn: 1.77 ± 0.043
4.146ArgPro: 4.146 ± 0.076
3.529ArgGln: 3.529 ± 0.063
6.496ArgArg: 6.496 ± 0.103
3.707ArgSer: 3.707 ± 0.05
3.415ArgThr: 3.415 ± 0.049
5.418ArgVal: 5.418 ± 0.078
1.406ArgTrp: 1.406 ± 0.039
1.807ArgTyr: 1.807 ± 0.041
0.0ArgXaa: 0.0 ± 0.0
Ser
5.977SerAla: 5.977 ± 0.076
0.463SerCys: 0.463 ± 0.022
2.197SerAsp: 2.197 ± 0.055
2.173SerGlu: 2.173 ± 0.047
1.9SerPhe: 1.9 ± 0.051
4.993SerGly: 4.993 ± 0.08
1.102SerHis: 1.102 ± 0.031
1.926SerIle: 1.926 ± 0.041
1.24SerLys: 1.24 ± 0.036
5.333SerLeu: 5.333 ± 0.065
1.244SerMet: 1.244 ± 0.033
1.159SerAsn: 1.159 ± 0.039
2.829SerPro: 2.829 ± 0.054
1.721SerGln: 1.721 ± 0.037
3.669SerArg: 3.669 ± 0.053
2.702SerSer: 2.702 ± 0.052
2.558SerThr: 2.558 ± 0.056
3.673SerVal: 3.673 ± 0.092
0.723SerTrp: 0.723 ± 0.024
1.235SerTyr: 1.235 ± 0.039
0.0SerXaa: 0.0 ± 0.0
Thr
6.074ThrAla: 6.074 ± 0.122
0.373ThrCys: 0.373 ± 0.017
2.262ThrAsp: 2.262 ± 0.048
2.164ThrGlu: 2.164 ± 0.043
1.513ThrPhe: 1.513 ± 0.04
4.777ThrGly: 4.777 ± 0.104
1.062ThrHis: 1.062 ± 0.032
1.749ThrIle: 1.749 ± 0.055
0.954ThrLys: 0.954 ± 0.036
5.956ThrLeu: 5.956 ± 0.106
0.958ThrMet: 0.958 ± 0.031
1.068ThrAsn: 1.068 ± 0.047
3.414ThrPro: 3.414 ± 0.072
1.789ThrGln: 1.789 ± 0.041
3.332ThrArg: 3.332 ± 0.049
2.39ThrSer: 2.39 ± 0.055
2.454ThrThr: 2.454 ± 0.077
4.233ThrVal: 4.233 ± 0.15
0.643ThrTrp: 0.643 ± 0.026
1.025ThrTyr: 1.025 ± 0.04
0.0ThrXaa: 0.0 ± 0.0
Val
10.029ValAla: 10.029 ± 0.117
0.683ValCys: 0.683 ± 0.025
4.011ValAsp: 4.011 ± 0.065
4.345ValGlu: 4.345 ± 0.065
2.722ValPhe: 2.722 ± 0.055
5.782ValGly: 5.782 ± 0.074
1.636ValHis: 1.636 ± 0.041
3.085ValIle: 3.085 ± 0.051
2.221ValLys: 2.221 ± 0.054
8.721ValLeu: 8.721 ± 0.094
1.818ValMet: 1.818 ± 0.043
2.061ValAsn: 2.061 ± 0.098
4.436ValPro: 4.436 ± 0.061
2.986ValGln: 2.986 ± 0.054
5.913ValArg: 5.913 ± 0.071
3.818ValSer: 3.818 ± 0.11
4.053ValThr: 4.053 ± 0.117
6.622ValVal: 6.622 ± 0.082
1.006ValTrp: 1.006 ± 0.029
1.544ValTyr: 1.544 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
1.541TrpAla: 1.541 ± 0.041
0.189TrpCys: 0.189 ± 0.013
0.671TrpAsp: 0.671 ± 0.024
0.599TrpGlu: 0.599 ± 0.023
0.574TrpPhe: 0.574 ± 0.023
1.083TrpGly: 1.083 ± 0.031
0.33TrpHis: 0.33 ± 0.016
0.57TrpIle: 0.57 ± 0.022
0.48TrpLys: 0.48 ± 0.022
2.139TrpLeu: 2.139 ± 0.05
0.421TrpMet: 0.421 ± 0.019
0.404TrpAsn: 0.404 ± 0.017
0.74TrpPro: 0.74 ± 0.028
0.808TrpGln: 0.808 ± 0.025
1.42TrpArg: 1.42 ± 0.036
0.778TrpSer: 0.778 ± 0.031
0.718TrpThr: 0.718 ± 0.023
1.064TrpVal: 1.064 ± 0.031
0.326TrpTrp: 0.326 ± 0.017
0.287TrpTyr: 0.287 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.473TyrAla: 2.473 ± 0.053
0.25TyrCys: 0.25 ± 0.014
1.136TyrAsp: 1.136 ± 0.034
1.161TyrGlu: 1.161 ± 0.03
0.811TyrPhe: 0.811 ± 0.028
2.004TyrGly: 2.004 ± 0.047
0.435TyrHis: 0.435 ± 0.018
0.696TyrIle: 0.696 ± 0.024
0.58TyrLys: 0.58 ± 0.026
2.343TyrLeu: 2.343 ± 0.045
0.371TyrMet: 0.371 ± 0.016
0.591TyrAsn: 0.591 ± 0.033
1.078TyrPro: 1.078 ± 0.035
0.783TyrGln: 0.783 ± 0.025
1.663TyrArg: 1.663 ± 0.036
1.088TyrSer: 1.088 ± 0.032
1.194TyrThr: 1.194 ± 0.054
1.499TyrVal: 1.499 ± 0.036
0.343TyrTrp: 0.343 ± 0.016
0.511TyrTyr: 0.511 ± 0.023
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3880 proteins (1249633 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski