Amino acid dipepetide frequency for Coniochaeta pulveracea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.725AlaAla: 9.725 ± 0.067	1.06AlaCys: 1.06 ± 0.017	4.471AlaAsp: 4.471 ± 0.035	5.448AlaGlu: 5.448 ± 0.053	2.96AlaPhe: 2.96 ± 0.027	6.379AlaGly: 6.379 ± 0.045	1.789AlaHis: 1.789 ± 0.018	4.017AlaIle: 4.017 ± 0.033	4.353AlaLys: 4.353 ± 0.037	7.731AlaLeu: 7.731 ± 0.049	2.133AlaMet: 2.133 ± 0.022	2.923AlaAsn: 2.923 ± 0.024	5.153AlaPro: 5.153 ± 0.051	3.595AlaGln: 3.595 ± 0.033	5.119AlaArg: 5.119 ± 0.032	7.318AlaSer: 7.318 ± 0.054	5.7AlaThr: 5.7 ± 0.039	5.854AlaVal: 5.854 ± 0.039	1.157AlaTrp: 1.157 ± 0.017	2.208AlaTyr: 2.208 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.923CysAla: 0.923 ± 0.016	0.241CysCys: 0.241 ± 0.008	0.629CysAsp: 0.629 ± 0.013	0.536CysGlu: 0.536 ± 0.011	0.517CysPhe: 0.517 ± 0.01	0.945CysGly: 0.945 ± 0.017	0.319CysHis: 0.319 ± 0.008	0.621CysIle: 0.621 ± 0.012	0.495CysLys: 0.495 ± 0.01	1.172CysLeu: 1.172 ± 0.016	0.263CysMet: 0.263 ± 0.007	0.401CysAsn: 0.401 ± 0.01	0.678CysPro: 0.678 ± 0.016	0.436CysGln: 0.436 ± 0.009	0.726CysArg: 0.726 ± 0.012	0.868CysSer: 0.868 ± 0.013	0.672CysThr: 0.672 ± 0.013	0.762CysVal: 0.762 ± 0.012	0.196CysTrp: 0.196 ± 0.007	0.35CysTyr: 0.35 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.822AspAla: 4.822 ± 0.034	0.607AspCys: 0.607 ± 0.012	4.511AspAsp: 4.511 ± 0.05	4.704AspGlu: 4.704 ± 0.043	2.133AspPhe: 2.133 ± 0.021	4.33AspGly: 4.33 ± 0.033	1.299AspHis: 1.299 ± 0.017	2.83AspIle: 2.83 ± 0.027	2.52AspLys: 2.52 ± 0.028	4.939AspLeu: 4.939 ± 0.036	1.376AspMet: 1.376 ± 0.017	1.893AspAsn: 1.893 ± 0.024	3.299AspPro: 3.299 ± 0.027	1.907AspGln: 1.907 ± 0.02	3.082AspArg: 3.082 ± 0.036	3.842AspSer: 3.842 ± 0.033	3.003AspThr: 3.003 ± 0.025	3.888AspVal: 3.888 ± 0.029	0.879AspTrp: 0.879 ± 0.014	1.613AspTyr: 1.613 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.672GluAla: 5.672 ± 0.049	0.574GluCys: 0.574 ± 0.012	4.468GluAsp: 4.468 ± 0.042	5.99GluGlu: 5.99 ± 0.061	1.786GluPhe: 1.786 ± 0.019	3.946GluGly: 3.946 ± 0.033	1.409GluHis: 1.409 ± 0.016	2.749GluIle: 2.749 ± 0.028	3.719GluLys: 3.719 ± 0.038	5.173GluLeu: 5.173 ± 0.039	1.475GluMet: 1.475 ± 0.017	2.015GluAsn: 2.015 ± 0.023	2.879GluPro: 2.879 ± 0.043	2.544GluGln: 2.544 ± 0.025	3.999GluArg: 3.999 ± 0.036	3.804GluSer: 3.804 ± 0.033	3.541GluThr: 3.541 ± 0.034	3.89GluVal: 3.89 ± 0.03	0.816GluTrp: 0.816 ± 0.013	1.601GluTyr: 1.601 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.957PheAla: 2.957 ± 0.026	0.522PheCys: 0.522 ± 0.01	2.157PheAsp: 2.157 ± 0.02	1.945PheGlu: 1.945 ± 0.021	1.499PhePhe: 1.499 ± 0.025	2.812PheGly: 2.812 ± 0.03	0.852PheHis: 0.852 ± 0.015	1.6PheIle: 1.6 ± 0.021	1.43PheLys: 1.43 ± 0.017	3.254PheLeu: 3.254 ± 0.033	0.741PheMet: 0.741 ± 0.012	1.347PheAsn: 1.347 ± 0.02	1.864PhePro: 1.864 ± 0.023	1.25PheGln: 1.25 ± 0.015	1.901PheArg: 1.901 ± 0.023	2.726PheSer: 2.726 ± 0.028	2.063PheThr: 2.063 ± 0.023	2.307PheVal: 2.307 ± 0.025	0.614PheTrp: 0.614 ± 0.012	1.053PheTyr: 1.053 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	5.634GlyAla: 5.634 ± 0.041	0.869GlyCys: 0.869 ± 0.013	3.817GlyAsp: 3.817 ± 0.029	3.843GlyGlu: 3.843 ± 0.03	2.713GlyPhe: 2.713 ± 0.028	6.473GlyGly: 6.473 ± 0.066	1.852GlyHis: 1.852 ± 0.023	3.32GlyIle: 3.32 ± 0.035	3.649GlyLys: 3.649 ± 0.038	6.177GlyLeu: 6.177 ± 0.038	1.682GlyMet: 1.682 ± 0.022	2.562GlyAsn: 2.562 ± 0.029	3.596GlyPro: 3.596 ± 0.035	2.807GlyGln: 2.807 ± 0.024	4.457GlyArg: 4.457 ± 0.031	5.894GlySer: 5.894 ± 0.046	4.311GlyThr: 4.311 ± 0.035	4.624GlyVal: 4.624 ± 0.032	1.214GlyTrp: 1.214 ± 0.018	2.204GlyTyr: 2.204 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.889HisAla: 1.889 ± 0.021	0.312HisCys: 0.312 ± 0.009	1.406HisAsp: 1.406 ± 0.017	1.336HisGlu: 1.336 ± 0.019	0.864HisPhe: 0.864 ± 0.013	1.873HisGly: 1.873 ± 0.022	0.931HisHis: 0.931 ± 0.015	1.144HisIle: 1.144 ± 0.018	0.961HisLys: 0.961 ± 0.014	2.186HisLeu: 2.186 ± 0.025	0.523HisMet: 0.523 ± 0.011	0.888HisAsn: 0.888 ± 0.014	1.691HisPro: 1.691 ± 0.021	1.057HisGln: 1.057 ± 0.017	1.533HisArg: 1.533 ± 0.021	1.744HisSer: 1.744 ± 0.021	1.313HisThr: 1.313 ± 0.017	1.511HisVal: 1.511 ± 0.019	0.314HisTrp: 0.314 ± 0.008	0.689HisTyr: 0.689 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.907IleAla: 3.907 ± 0.032	0.673IleCys: 0.673 ± 0.013	2.541IleAsp: 2.541 ± 0.029	2.534IleGlu: 2.534 ± 0.026	1.744IlePhe: 1.744 ± 0.023	2.969IleGly: 2.969 ± 0.031	1.116IleHis: 1.116 ± 0.015	2.186IleIle: 2.186 ± 0.024	2.06IleLys: 2.06 ± 0.025	4.115IleLeu: 4.115 ± 0.037	0.997IleMet: 0.997 ± 0.016	1.663IleAsn: 1.663 ± 0.021	2.935IlePro: 2.935 ± 0.025	1.734IleGln: 1.734 ± 0.019	2.675IleArg: 2.675 ± 0.025	3.425IleSer: 3.425 ± 0.028	2.754IleThr: 2.754 ± 0.026	3.002IleVal: 3.002 ± 0.029	0.693IleTrp: 0.693 ± 0.013	1.283IleTyr: 1.283 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.502LysAla: 4.502 ± 0.045	0.474LysCys: 0.474 ± 0.011	2.823LysAsp: 2.823 ± 0.029	3.509LysGlu: 3.509 ± 0.041	1.357LysPhe: 1.357 ± 0.018	3.121LysGly: 3.121 ± 0.028	1.146LysHis: 1.146 ± 0.016	2.056LysIle: 2.056 ± 0.02	3.479LysLys: 3.479 ± 0.046	3.995LysLeu: 3.995 ± 0.035	1.027LysMet: 1.027 ± 0.014	1.629LysAsn: 1.629 ± 0.021	2.861LysPro: 2.861 ± 0.037	1.87LysGln: 1.87 ± 0.023	3.444LysArg: 3.444 ± 0.03	3.251LysSer: 3.251 ± 0.03	2.929LysThr: 2.929 ± 0.028	2.941LysVal: 2.941 ± 0.032	0.659LysTrp: 0.659 ± 0.014	1.314LysTyr: 1.314 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.029LeuAla: 8.029 ± 0.05	1.126LeuCys: 1.126 ± 0.017	5.167LeuAsp: 5.167 ± 0.04	5.428LeuGlu: 5.428 ± 0.046	3.071LeuPhe: 3.071 ± 0.033	6.021LeuGly: 6.021 ± 0.041	2.137LeuHis: 2.137 ± 0.023	3.591LeuIle: 3.591 ± 0.036	4.078LeuLys: 4.078 ± 0.039	7.977LeuLeu: 7.977 ± 0.064	1.758LeuMet: 1.758 ± 0.018	2.963LeuAsn: 2.963 ± 0.025	5.601LeuPro: 5.601 ± 0.041	3.648LeuGln: 3.648 ± 0.03	5.539LeuArg: 5.539 ± 0.041	6.894LeuSer: 6.894 ± 0.045	4.953LeuThr: 4.953 ± 0.034	5.548LeuVal: 5.548 ± 0.043	1.129LeuTrp: 1.129 ± 0.015	2.253LeuTyr: 2.253 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.351MetAla: 2.351 ± 0.022	0.243MetCys: 0.243 ± 0.007	1.304MetAsp: 1.304 ± 0.018	1.308MetGlu: 1.308 ± 0.018	0.746MetPhe: 0.746 ± 0.013	1.542MetGly: 1.542 ± 0.021	0.475MetHis: 0.475 ± 0.01	0.927MetIle: 0.927 ± 0.016	0.986MetLys: 0.986 ± 0.015	1.878MetLeu: 1.878 ± 0.023	0.587MetMet: 0.587 ± 0.011	0.762MetAsn: 0.762 ± 0.014	1.27MetPro: 1.27 ± 0.017	0.83MetGln: 0.83 ± 0.017	1.262MetArg: 1.262 ± 0.015	1.886MetSer: 1.886 ± 0.021	1.386MetThr: 1.386 ± 0.017	1.41MetVal: 1.41 ± 0.018	0.267MetTrp: 0.267 ± 0.007	0.538MetTyr: 0.538 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.934AsnAla: 2.934 ± 0.026	0.441AsnCys: 0.441 ± 0.01	1.833AsnAsp: 1.833 ± 0.019	1.864AsnGlu: 1.864 ± 0.019	1.242AsnPhe: 1.242 ± 0.017	2.974AsnGly: 2.974 ± 0.032	0.889AsnHis: 0.889 ± 0.012	1.814AsnIle: 1.814 ± 0.02	1.583AsnLys: 1.583 ± 0.02	3.096AsnLeu: 3.096 ± 0.026	0.85AsnMet: 0.85 ± 0.016	1.441AsnAsn: 1.441 ± 0.021	2.438AsnPro: 2.438 ± 0.026	1.309AsnGln: 1.309 ± 0.018	1.919AsnArg: 1.919 ± 0.02	2.512AsnSer: 2.512 ± 0.024	2.171AsnThr: 2.171 ± 0.023	2.211AsnVal: 2.211 ± 0.019	0.537AsnTrp: 0.537 ± 0.01	0.989AsnTyr: 0.989 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.915ProAla: 5.915 ± 0.066	0.517ProCys: 0.517 ± 0.011	3.312ProAsp: 3.312 ± 0.025	3.804ProGlu: 3.804 ± 0.034	1.973ProPhe: 1.973 ± 0.022	4.408ProGly: 4.408 ± 0.043	1.345ProHis: 1.345 ± 0.018	2.372ProIle: 2.372 ± 0.021	2.685ProLys: 2.685 ± 0.03	4.793ProLeu: 4.793 ± 0.039	1.091ProMet: 1.091 ± 0.016	2.164ProAsn: 2.164 ± 0.024	5.562ProPro: 5.562 ± 0.081	2.523ProGln: 2.523 ± 0.035	3.455ProArg: 3.455 ± 0.031	6.079ProSer: 6.079 ± 0.056	4.383ProThr: 4.383 ± 0.045	4.041ProVal: 4.041 ± 0.039	0.745ProTrp: 0.745 ± 0.013	1.549ProTyr: 1.549 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.778GlnAla: 3.778 ± 0.029	0.417GlnCys: 0.417 ± 0.009	2.088GlnAsp: 2.088 ± 0.022	2.447GlnGlu: 2.447 ± 0.026	1.214GlnPhe: 1.214 ± 0.016	2.517GlnGly: 2.517 ± 0.027	1.16GlnHis: 1.16 ± 0.019	1.724GlnIle: 1.724 ± 0.018	1.867GlnLys: 1.867 ± 0.021	3.415GlnLeu: 3.415 ± 0.029	0.873GlnMet: 0.873 ± 0.014	1.387GlnAsn: 1.387 ± 0.017	2.86GlnPro: 2.86 ± 0.036	2.825GlnGln: 2.825 ± 0.061	2.591GlnArg: 2.591 ± 0.028	2.926GlnSer: 2.926 ± 0.027	2.417GlnThr: 2.417 ± 0.022	2.286GlnVal: 2.286 ± 0.024	0.544GlnTrp: 0.544 ± 0.011	1.159GlnTyr: 1.159 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.819ArgAla: 4.819 ± 0.038	0.675ArgCys: 0.675 ± 0.012	3.468ArgAsp: 3.468 ± 0.034	3.868ArgGlu: 3.868 ± 0.034	2.04ArgPhe: 2.04 ± 0.022	3.863ArgGly: 3.863 ± 0.033	1.622ArgHis: 1.622 ± 0.019	2.7ArgIle: 2.7 ± 0.022	3.45ArgLys: 3.45 ± 0.03	5.454ArgLeu: 5.454 ± 0.039	1.343ArgMet: 1.343 ± 0.017	2.195ArgAsn: 2.195 ± 0.022	3.757ArgPro: 3.757 ± 0.035	2.71ArgGln: 2.71 ± 0.026	5.3ArgArg: 5.3 ± 0.045	4.648ArgSer: 4.648 ± 0.043	3.483ArgThr: 3.483 ± 0.028	3.406ArgVal: 3.406 ± 0.028	0.917ArgTrp: 0.917 ± 0.014	1.634ArgTyr: 1.634 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.611SerAla: 6.611 ± 0.049	0.816SerCys: 0.816 ± 0.013	3.997SerAsp: 3.997 ± 0.037	3.807SerGlu: 3.807 ± 0.03	2.799SerPhe: 2.799 ± 0.027	5.614SerGly: 5.614 ± 0.049	1.944SerHis: 1.944 ± 0.02	3.537SerIle: 3.537 ± 0.032	3.454SerLys: 3.454 ± 0.033	6.829SerLeu: 6.829 ± 0.045	1.654SerMet: 1.654 ± 0.018	2.767SerAsn: 2.767 ± 0.024	5.541SerPro: 5.541 ± 0.056	3.175SerGln: 3.175 ± 0.03	4.925SerArg: 4.925 ± 0.042	8.557SerSer: 8.557 ± 0.085	5.762SerThr: 5.762 ± 0.054	4.675SerVal: 4.675 ± 0.035	1.062SerTrp: 1.062 ± 0.015	2.056SerTyr: 2.056 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.672ThrAla: 5.672 ± 0.038	0.769ThrCys: 0.769 ± 0.014	3.005ThrAsp: 3.005 ± 0.029	3.229ThrGlu: 3.229 ± 0.031	2.168ThrPhe: 2.168 ± 0.02	4.593ThrGly: 4.593 ± 0.038	1.309ThrHis: 1.309 ± 0.017	2.994ThrIle: 2.994 ± 0.028	2.695ThrLys: 2.695 ± 0.024	5.193ThrLeu: 5.193 ± 0.037	1.239ThrMet: 1.239 ± 0.016	2.114ThrAsn: 2.114 ± 0.023	4.694ThrPro: 4.694 ± 0.047	2.143ThrGln: 2.143 ± 0.023	3.271ThrArg: 3.271 ± 0.027	5.608ThrSer: 5.608 ± 0.052	4.893ThrThr: 4.893 ± 0.058	4.161ThrVal: 4.161 ± 0.037	0.842ThrTrp: 0.842 ± 0.013	1.663ThrTyr: 1.663 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.667ValAla: 5.667 ± 0.035	0.816ValCys: 0.816 ± 0.015	3.91ValAsp: 3.91 ± 0.032	4.11ValGlu: 4.11 ± 0.037	2.358ValPhe: 2.358 ± 0.026	4.238ValGly: 4.238 ± 0.037	1.442ValHis: 1.442 ± 0.016	2.872ValIle: 2.872 ± 0.026	3.084ValLys: 3.084 ± 0.031	5.657ValLeu: 5.657 ± 0.043	1.358ValMet: 1.358 ± 0.018	2.213ValAsn: 2.213 ± 0.023	3.904ValPro: 3.904 ± 0.038	2.474ValGln: 2.474 ± 0.025	3.647ValArg: 3.647 ± 0.029	4.674ValSer: 4.674 ± 0.036	3.98ValThr: 3.98 ± 0.034	4.698ValVal: 4.698 ± 0.037	0.888ValTrp: 0.888 ± 0.015	1.745ValTyr: 1.745 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.126TrpAla: 1.126 ± 0.015	0.195TrpCys: 0.195 ± 0.006	0.892TrpAsp: 0.892 ± 0.013	0.829TrpGlu: 0.829 ± 0.013	0.557TrpPhe: 0.557 ± 0.011	0.924TrpGly: 0.924 ± 0.016	0.347TrpHis: 0.347 ± 0.009	0.681TrpIle: 0.681 ± 0.013	0.758TrpLys: 0.758 ± 0.012	1.318TrpLeu: 1.318 ± 0.018	0.369TrpMet: 0.369 ± 0.008	0.597TrpAsn: 0.597 ± 0.012	0.607TrpPro: 0.607 ± 0.012	0.558TrpGln: 0.558 ± 0.011	0.925TrpArg: 0.925 ± 0.015	1.004TrpSer: 1.004 ± 0.014	0.937TrpThr: 0.937 ± 0.015	0.858TrpVal: 0.858 ± 0.013	0.274TrpTrp: 0.274 ± 0.008	0.418TrpTyr: 0.418 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.158TyrAla: 2.158 ± 0.021	0.404TyrCys: 0.404 ± 0.01	1.677TyrAsp: 1.677 ± 0.021	1.508TyrGlu: 1.508 ± 0.022	1.148TyrPhe: 1.148 ± 0.016	2.156TyrGly: 2.156 ± 0.023	0.783TyrHis: 0.783 ± 0.014	1.272TyrIle: 1.272 ± 0.018	1.082TyrLys: 1.082 ± 0.015	2.558TyrLeu: 2.558 ± 0.023	0.62TyrMet: 0.62 ± 0.011	1.123TyrAsn: 1.123 ± 0.014	1.523TyrPro: 1.523 ± 0.022	1.104TyrGln: 1.104 ± 0.016	1.585TyrArg: 1.585 ± 0.019	1.923TyrSer: 1.923 ± 0.022	1.606TyrThr: 1.606 ± 0.021	1.662TyrVal: 1.662 ± 0.018	0.427TyrTrp: 0.427 ± 0.01	0.929TyrTyr: 0.929 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10012 proteins (4982711 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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