Amino acid dipepetide frequency for Anthracocystis flocculosa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.338AlaAla: 19.338 ± 0.149	1.119AlaCys: 1.119 ± 0.021	6.114AlaAsp: 6.114 ± 0.047	6.05AlaGlu: 6.05 ± 0.053	3.145AlaPhe: 3.145 ± 0.031	9.297AlaGly: 9.297 ± 0.062	2.345AlaHis: 2.345 ± 0.025	3.714AlaIle: 3.714 ± 0.034	4.796AlaLys: 4.796 ± 0.043	8.844AlaLeu: 8.844 ± 0.059	2.126AlaMet: 2.126 ± 0.023	2.972AlaAsn: 2.972 ± 0.032	7.542AlaPro: 7.542 ± 0.069	4.412AlaGln: 4.412 ± 0.037	7.527AlaArg: 7.527 ± 0.051	12.619AlaSer: 12.619 ± 0.08	7.18AlaThr: 7.18 ± 0.05	6.049AlaVal: 6.049 ± 0.047	1.24AlaTrp: 1.24 ± 0.02	2.071AlaTyr: 2.071 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.884CysAla: 0.884 ± 0.015	0.222CysCys: 0.222 ± 0.009	0.562CysAsp: 0.562 ± 0.013	0.449CysGlu: 0.449 ± 0.012	0.408CysPhe: 0.408 ± 0.009	0.794CysGly: 0.794 ± 0.017	0.298CysHis: 0.298 ± 0.009	0.482CysIle: 0.482 ± 0.012	0.4CysLys: 0.4 ± 0.01	1.121CysLeu: 1.121 ± 0.021	0.179CysMet: 0.179 ± 0.007	0.293CysAsn: 0.293 ± 0.009	0.612CysPro: 0.612 ± 0.013	0.393CysGln: 0.393 ± 0.009	0.754CysArg: 0.754 ± 0.013	0.811CysSer: 0.811 ± 0.014	0.583CysThr: 0.583 ± 0.017	0.631CysVal: 0.631 ± 0.014	0.17CysTrp: 0.17 ± 0.007	0.262CysTyr: 0.262 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	7.169AspAla: 7.169 ± 0.046	0.511AspCys: 0.511 ± 0.012	6.73AspAsp: 6.73 ± 0.103	5.16AspGlu: 5.16 ± 0.051	1.804AspPhe: 1.804 ± 0.025	5.533AspGly: 5.533 ± 0.046	1.287AspHis: 1.287 ± 0.019	1.91AspIle: 1.91 ± 0.022	2.045AspLys: 2.045 ± 0.026	4.947AspLeu: 4.947 ± 0.036	0.957AspMet: 0.957 ± 0.016	1.356AspAsn: 1.356 ± 0.02	3.606AspPro: 3.606 ± 0.027	1.944AspGln: 1.944 ± 0.023	3.794AspArg: 3.794 ± 0.036	3.904AspSer: 3.904 ± 0.036	2.461AspThr: 2.461 ± 0.027	3.755AspVal: 3.755 ± 0.03	0.755AspTrp: 0.755 ± 0.015	1.202AspTyr: 1.202 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	6.947GluAla: 6.947 ± 0.052	0.457GluCys: 0.457 ± 0.012	3.757GluAsp: 3.757 ± 0.039	4.398GluGlu: 4.398 ± 0.059	1.265GluPhe: 1.265 ± 0.016	4.147GluGly: 4.147 ± 0.036	1.257GluHis: 1.257 ± 0.019	1.965GluIle: 1.965 ± 0.023	2.319GluLys: 2.319 ± 0.03	4.728GluLeu: 4.728 ± 0.043	1.202GluMet: 1.202 ± 0.018	1.113GluAsn: 1.113 ± 0.018	2.667GluPro: 2.667 ± 0.029	2.403GluGln: 2.403 ± 0.026	4.618GluArg: 4.618 ± 0.046	3.531GluSer: 3.531 ± 0.035	2.643GluThr: 2.643 ± 0.025	3.227GluVal: 3.227 ± 0.031	0.708GluTrp: 0.708 ± 0.014	1.063GluTyr: 1.063 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.102PheAla: 3.102 ± 0.03	0.415PheCys: 0.415 ± 0.009	2.133PheAsp: 2.133 ± 0.026	1.737PheGlu: 1.737 ± 0.022	1.186PhePhe: 1.186 ± 0.021	2.709PheGly: 2.709 ± 0.033	0.707PheHis: 0.707 ± 0.013	1.045PheIle: 1.045 ± 0.019	1.054PheLys: 1.054 ± 0.019	2.651PheLeu: 2.651 ± 0.031	0.484PheMet: 0.484 ± 0.011	0.923PheAsn: 0.923 ± 0.015	1.467PhePro: 1.467 ± 0.019	1.01PheGln: 1.01 ± 0.019	1.775PheArg: 1.775 ± 0.021	2.381PheSer: 2.381 ± 0.023	1.451PheThr: 1.451 ± 0.02	2.03PheVal: 2.03 ± 0.028	0.443PheTrp: 0.443 ± 0.011	0.79PheTyr: 0.79 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	8.527GlyAla: 8.527 ± 0.073	0.797GlyCys: 0.797 ± 0.015	4.576GlyAsp: 4.576 ± 0.043	3.836GlyGlu: 3.836 ± 0.033	2.408GlyPhe: 2.408 ± 0.031	10.025GlyGly: 10.025 ± 0.114	1.952GlyHis: 1.952 ± 0.026	2.771GlyIle: 2.771 ± 0.024	3.356GlyLys: 3.356 ± 0.033	6.133GlyLeu: 6.133 ± 0.047	1.48GlyMet: 1.48 ± 0.023	2.086GlyAsn: 2.086 ± 0.024	4.538GlyPro: 4.538 ± 0.041	3.247GlyGln: 3.247 ± 0.034	5.596GlyArg: 5.596 ± 0.05	7.982GlySer: 7.982 ± 0.063	4.15GlyThr: 4.15 ± 0.036	4.1GlyVal: 4.1 ± 0.035	1.093GlyTrp: 1.093 ± 0.019	1.75GlyTyr: 1.75 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.55HisAla: 2.55 ± 0.031	0.269HisCys: 0.269 ± 0.008	1.484HisAsp: 1.484 ± 0.021	1.143HisGlu: 1.143 ± 0.018	0.817HisPhe: 0.817 ± 0.015	1.996HisGly: 1.996 ± 0.025	1.186HisHis: 1.186 ± 0.029	0.846HisIle: 0.846 ± 0.013	0.675HisLys: 0.675 ± 0.013	2.376HisLeu: 2.376 ± 0.028	0.338HisMet: 0.338 ± 0.009	0.583HisAsn: 0.583 ± 0.012	1.868HisPro: 1.868 ± 0.026	1.147HisGln: 1.147 ± 0.024	1.933HisArg: 1.933 ± 0.025	1.822HisSer: 1.822 ± 0.025	1.091HisThr: 1.091 ± 0.016	1.319HisVal: 1.319 ± 0.018	0.251HisTrp: 0.251 ± 0.008	0.539HisTyr: 0.539 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.544IleAla: 3.544 ± 0.034	0.485IleCys: 0.485 ± 0.012	2.549IleAsp: 2.549 ± 0.026	2.221IleGlu: 2.221 ± 0.027	1.221IlePhe: 1.221 ± 0.022	2.452IleGly: 2.452 ± 0.024	0.817IleHis: 0.817 ± 0.014	1.266IleIle: 1.266 ± 0.023	1.56IleLys: 1.56 ± 0.022	3.108IleLeu: 3.108 ± 0.04	0.575IleMet: 0.575 ± 0.013	1.097IleAsn: 1.097 ± 0.016	1.981IlePro: 1.981 ± 0.021	1.275IleGln: 1.275 ± 0.017	2.375IleArg: 2.375 ± 0.026	2.67IleSer: 2.67 ± 0.026	1.71IleThr: 1.71 ± 0.024	2.343IleVal: 2.343 ± 0.026	0.444IleTrp: 0.444 ± 0.011	0.839IleTyr: 0.839 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.718LysAla: 4.718 ± 0.047	0.331LysCys: 0.331 ± 0.01	2.163LysAsp: 2.163 ± 0.026	2.335LysGlu: 2.335 ± 0.028	0.886LysPhe: 0.886 ± 0.016	2.786LysGly: 2.786 ± 0.031	0.874LysHis: 0.874 ± 0.014	1.377LysIle: 1.377 ± 0.018	2.581LysLys: 2.581 ± 0.043	3.357LysLeu: 3.357 ± 0.034	0.81LysMet: 0.81 ± 0.014	0.979LysAsn: 0.979 ± 0.016	2.331LysPro: 2.331 ± 0.033	1.726LysGln: 1.726 ± 0.023	3.504LysArg: 3.504 ± 0.034	2.614LysSer: 2.614 ± 0.026	2.154LysThr: 2.154 ± 0.027	2.487LysVal: 2.487 ± 0.026	0.435LysTrp: 0.435 ± 0.009	0.743LysTyr: 0.743 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	9.583LeuAla: 9.583 ± 0.058	1.113LeuCys: 1.113 ± 0.019	5.617LeuAsp: 5.617 ± 0.042	4.915LeuGlu: 4.915 ± 0.038	2.778LeuPhe: 2.778 ± 0.032	6.13LeuGly: 6.13 ± 0.045	2.076LeuHis: 2.076 ± 0.023	2.831LeuIle: 2.831 ± 0.035	3.106LeuLys: 3.106 ± 0.034	8.055LeuLeu: 8.055 ± 0.066	1.395LeuMet: 1.395 ± 0.017	2.247LeuAsn: 2.247 ± 0.025	5.944LeuPro: 5.944 ± 0.043	3.451LeuGln: 3.451 ± 0.03	6.192LeuArg: 6.192 ± 0.038	7.439LeuSer: 7.439 ± 0.044	4.063LeuThr: 4.063 ± 0.036	5.496LeuVal: 5.496 ± 0.051	0.932LeuTrp: 0.932 ± 0.016	1.833LeuTyr: 1.833 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.231MetAla: 2.231 ± 0.024	0.166MetCys: 0.166 ± 0.006	1.019MetAsp: 1.019 ± 0.016	0.838MetGlu: 0.838 ± 0.015	0.457MetPhe: 0.457 ± 0.011	1.295MetGly: 1.295 ± 0.021	0.401MetHis: 0.401 ± 0.008	0.594MetIle: 0.594 ± 0.013	0.608MetLys: 0.608 ± 0.013	1.68MetLeu: 1.68 ± 0.02	0.436MetMet: 0.436 ± 0.011	0.424MetAsn: 0.424 ± 0.01	1.367MetPro: 1.367 ± 0.018	0.772MetGln: 0.772 ± 0.015	1.215MetArg: 1.215 ± 0.016	1.67MetSer: 1.67 ± 0.021	1.045MetThr: 1.045 ± 0.017	1.074MetVal: 1.074 ± 0.016	0.197MetTrp: 0.197 ± 0.007	0.321MetTyr: 0.321 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.902AsnAla: 2.902 ± 0.028	0.245AsnCys: 0.245 ± 0.008	1.557AsnAsp: 1.557 ± 0.018	1.32AsnGlu: 1.32 ± 0.021	0.842AsnPhe: 0.842 ± 0.013	2.608AsnGly: 2.608 ± 0.032	0.594AsnHis: 0.594 ± 0.011	0.984AsnIle: 0.984 ± 0.018	1.017AsnLys: 1.017 ± 0.016	2.426AsnLeu: 2.426 ± 0.029	0.48AsnMet: 0.48 ± 0.01	0.858AsnAsn: 0.858 ± 0.019	1.713AsnPro: 1.713 ± 0.021	0.888AsnGln: 0.888 ± 0.014	1.641AsnArg: 1.641 ± 0.018	1.862AsnSer: 1.862 ± 0.022	1.312AsnThr: 1.312 ± 0.019	1.745AsnVal: 1.745 ± 0.024	0.316AsnTrp: 0.316 ± 0.009	0.597AsnTyr: 0.597 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	8.49ProAla: 8.49 ± 0.072	0.547ProCys: 0.547 ± 0.013	3.23ProAsp: 3.23 ± 0.027	2.937ProGlu: 2.937 ± 0.026	1.888ProPhe: 1.888 ± 0.025	4.679ProGly: 4.679 ± 0.049	1.61ProHis: 1.61 ± 0.025	2.014ProIle: 2.014 ± 0.024	2.154ProLys: 2.154 ± 0.028	5.283ProLeu: 5.283 ± 0.039	1.025ProMet: 1.025 ± 0.017	1.658ProAsn: 1.658 ± 0.02	6.993ProPro: 6.993 ± 0.102	2.529ProGln: 2.529 ± 0.036	4.403ProArg: 4.403 ± 0.045	8.517ProSer: 8.517 ± 0.075	4.317ProThr: 4.317 ± 0.036	3.35ProVal: 3.35 ± 0.03	0.644ProTrp: 0.644 ± 0.011	1.271ProTyr: 1.271 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	4.704GlnAla: 4.704 ± 0.04	0.314GlnCys: 0.314 ± 0.009	2.07GlnAsp: 2.07 ± 0.022	1.966GlnGlu: 1.966 ± 0.024	0.876GlnPhe: 0.876 ± 0.015	2.858GlnGly: 2.858 ± 0.03	1.447GlnHis: 1.447 ± 0.025	1.337GlnIle: 1.337 ± 0.021	1.417GlnLys: 1.417 ± 0.02	3.542GlnLeu: 3.542 ± 0.032	0.805GlnMet: 0.805 ± 0.014	0.951GlnAsn: 0.951 ± 0.013	3.253GlnPro: 3.253 ± 0.04	4.384GlnGln: 4.384 ± 0.114	3.486GlnArg: 3.486 ± 0.036	2.943GlnSer: 2.943 ± 0.032	1.969GlnThr: 1.969 ± 0.019	2.057GlnVal: 2.057 ± 0.021	0.42GlnTrp: 0.42 ± 0.01	0.738GlnTyr: 0.738 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	6.94ArgAla: 6.94 ± 0.053	0.837ArgCys: 0.837 ± 0.015	3.927ArgAsp: 3.927 ± 0.04	3.739ArgGlu: 3.739 ± 0.041	2.145ArgPhe: 2.145 ± 0.023	5.02ArgGly: 5.02 ± 0.038	1.929ArgHis: 1.929 ± 0.026	2.773ArgIle: 2.773 ± 0.027	3.231ArgLys: 3.231 ± 0.034	6.347ArgLeu: 6.347 ± 0.043	1.303ArgMet: 1.303 ± 0.016	1.975ArgAsn: 1.975 ± 0.02	5.076ArgPro: 5.076 ± 0.047	3.303ArgGln: 3.303 ± 0.03	7.113ArgArg: 7.113 ± 0.069	6.787ArgSer: 6.787 ± 0.054	3.809ArgThr: 3.809 ± 0.034	3.222ArgVal: 3.222 ± 0.027	0.928ArgTrp: 0.928 ± 0.015	1.54ArgTyr: 1.54 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	10.766SerAla: 10.766 ± 0.076	0.788SerCys: 0.788 ± 0.017	4.726SerAsp: 4.726 ± 0.041	3.688SerGlu: 3.688 ± 0.032	2.689SerPhe: 2.689 ± 0.028	7.23SerGly: 7.23 ± 0.059	2.122SerHis: 2.122 ± 0.026	3.217SerIle: 3.217 ± 0.029	3.255SerLys: 3.255 ± 0.031	7.611SerLeu: 7.611 ± 0.048	1.642SerMet: 1.642 ± 0.021	2.474SerAsn: 2.474 ± 0.027	6.714SerPro: 6.714 ± 0.065	3.427SerGln: 3.427 ± 0.037	6.385SerArg: 6.385 ± 0.054	13.874SerSer: 13.874 ± 0.14	6.47SerThr: 6.47 ± 0.046	4.43SerVal: 4.43 ± 0.032	0.919SerTrp: 0.919 ± 0.014	1.721SerTyr: 1.721 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	6.947ThrAla: 6.947 ± 0.045	0.571ThrCys: 0.571 ± 0.013	2.655ThrAsp: 2.655 ± 0.026	2.365ThrGlu: 2.365 ± 0.023	1.741ThrPhe: 1.741 ± 0.021	4.107ThrGly: 4.107 ± 0.031	1.131ThrHis: 1.131 ± 0.017	2.103ThrIle: 2.103 ± 0.026	1.978ThrLys: 1.978 ± 0.023	4.783ThrLeu: 4.783 ± 0.031	0.988ThrMet: 0.988 ± 0.015	1.368ThrAsn: 1.368 ± 0.018	4.447ThrPro: 4.447 ± 0.046	1.72ThrGln: 1.72 ± 0.021	3.312ThrArg: 3.312 ± 0.028	5.866ThrSer: 5.866 ± 0.043	4.234ThrThr: 4.234 ± 0.046	3.143ThrVal: 3.143 ± 0.028	0.633ThrTrp: 0.633 ± 0.012	1.142ThrTyr: 1.142 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	6.203ValAla: 6.203 ± 0.047	0.676ValCys: 0.676 ± 0.016	3.858ValAsp: 3.858 ± 0.03	3.671ValGlu: 3.671 ± 0.029	1.817ValPhe: 1.817 ± 0.024	4.238ValGly: 4.238 ± 0.034	1.318ValHis: 1.318 ± 0.017	1.938ValIle: 1.938 ± 0.027	2.354ValLys: 2.354 ± 0.028	5.037ValLeu: 5.037 ± 0.048	0.958ValMet: 0.958 ± 0.018	1.47ValAsn: 1.47 ± 0.021	3.614ValPro: 3.614 ± 0.029	2.212ValGln: 2.212 ± 0.023	3.895ValArg: 3.895 ± 0.034	4.328ValSer: 4.328 ± 0.038	2.707ValThr: 2.707 ± 0.029	4.142ValVal: 4.142 ± 0.036	0.737ValTrp: 0.737 ± 0.014	1.279ValTyr: 1.279 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	0.98TrpAla: 0.98 ± 0.015	0.17TrpCys: 0.17 ± 0.006	0.704TrpAsp: 0.704 ± 0.013	0.561TrpGlu: 0.561 ± 0.013	0.357TrpPhe: 0.357 ± 0.009	0.703TrpGly: 0.703 ± 0.013	0.312TrpHis: 0.312 ± 0.009	0.558TrpIle: 0.558 ± 0.01	0.571TrpLys: 0.571 ± 0.012	1.153TrpLeu: 1.153 ± 0.018	0.263TrpMet: 0.263 ± 0.008	0.429TrpAsn: 0.429 ± 0.01	0.637TrpPro: 0.637 ± 0.013	0.552TrpGln: 0.552 ± 0.011	0.901TrpArg: 0.901 ± 0.015	1.034TrpSer: 1.034 ± 0.017	0.775TrpThr: 0.775 ± 0.013	0.574TrpVal: 0.574 ± 0.012	0.226TrpTrp: 0.226 ± 0.007	0.296TrpTyr: 0.296 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.971TyrAla: 1.971 ± 0.024	0.274TyrCys: 0.274 ± 0.008	1.399TyrAsp: 1.399 ± 0.018	1.082TyrGlu: 1.082 ± 0.016	0.766TyrPhe: 0.766 ± 0.014	1.797TyrGly: 1.797 ± 0.029	0.569TyrHis: 0.569 ± 0.013	0.807TyrIle: 0.807 ± 0.014	0.715TyrLys: 0.715 ± 0.014	2.014TyrLeu: 2.014 ± 0.023	0.366TyrMet: 0.366 ± 0.009	0.652TyrAsn: 0.652 ± 0.014	1.171TyrPro: 1.171 ± 0.018	0.742TyrGln: 0.742 ± 0.012	1.524TyrArg: 1.524 ± 0.023	1.494TyrSer: 1.494 ± 0.02	1.11TyrThr: 1.11 ± 0.02	1.279TyrVal: 1.279 ± 0.019	0.265TyrTrp: 0.265 ± 0.008	0.575TyrTyr: 0.575 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7767 proteins (4554219 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---