Amino acid dipepetide frequency for Beihai weivirus-like virus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.794AlaAla: 17.794 ± 7.554
2.135AlaCys: 2.135 ± 0.633
7.117AlaAsp: 7.117 ± 2.135
4.27AlaGlu: 4.27 ± 0.503
2.847AlaPhe: 2.847 ± 1.239
8.541AlaGly: 8.541 ± 2.068
2.135AlaHis: 2.135 ± 1.686
5.694AlaIle: 5.694 ± 2.383
0.712AlaLys: 0.712 ± 0.711
7.117AlaLeu: 7.117 ± 2.713
0.712AlaMet: 0.712 ± 0.398
1.423AlaAsn: 1.423 ± 0.796
6.406AlaPro: 6.406 ± 1.899
2.135AlaGln: 2.135 ± 0.74
7.829AlaArg: 7.829 ± 0.369
7.117AlaSer: 7.117 ± 3.739
8.541AlaThr: 8.541 ± 2.106
7.829AlaVal: 7.829 ± 2.347
3.559AlaTrp: 3.559 ± 1.175
2.135AlaTyr: 2.135 ± 1.686
0.0AlaXaa: 0.0 ± 0.0
Cys
3.559CysAla: 3.559 ± 1.423
1.423CysCys: 1.423 ± 0.796
0.712CysAsp: 0.712 ± 0.398
0.712CysGlu: 0.712 ± 0.965
0.0CysPhe: 0.0 ± 0.0
2.135CysGly: 2.135 ± 0.633
2.847CysHis: 2.847 ± 0.891
0.0CysIle: 0.0 ± 0.0
1.423CysLys: 1.423 ± 0.796
1.423CysLeu: 1.423 ± 0.796
2.135CysMet: 2.135 ± 1.686
1.423CysAsn: 1.423 ± 1.131
0.0CysPro: 0.0 ± 0.0
0.712CysGln: 0.712 ± 0.398
1.423CysArg: 1.423 ± 0.754
1.423CysSer: 1.423 ± 1.93
0.712CysThr: 0.712 ± 0.398
0.712CysVal: 0.712 ± 0.398
0.712CysTrp: 0.712 ± 0.398
0.712CysTyr: 0.712 ± 0.398
0.0CysXaa: 0.0 ± 0.0
Asp
6.406AspAla: 6.406 ± 0.908
1.423AspCys: 1.423 ± 0.796
4.982AspAsp: 4.982 ± 1.573
2.847AspGlu: 2.847 ± 0.365
2.135AspPhe: 2.135 ± 1.2
6.406AspGly: 6.406 ± 0.421
0.0AspHis: 0.0 ± 0.0
4.27AspIle: 4.27 ± 1.543
3.559AspLys: 3.559 ± 1.989
6.406AspLeu: 6.406 ± 2.626
0.712AspMet: 0.712 ± 0.398
0.712AspAsn: 0.712 ± 0.398
3.559AspPro: 3.559 ± 0.187
3.559AspGln: 3.559 ± 1.423
2.847AspArg: 2.847 ± 0.891
2.135AspSer: 2.135 ± 1.194
3.559AspThr: 3.559 ± 1.423
2.847AspVal: 2.847 ± 0.907
0.712AspTrp: 0.712 ± 0.965
1.423AspTyr: 1.423 ± 0.796
0.0AspXaa: 0.0 ± 0.0
Glu
4.27GluAla: 4.27 ± 1.512
0.712GluCys: 0.712 ± 0.398
4.27GluAsp: 4.27 ± 0.535
4.982GluGlu: 4.982 ± 2.16
2.135GluPhe: 2.135 ± 0.633
6.406GluGly: 6.406 ± 0.886
0.712GluHis: 0.712 ± 0.398
0.712GluIle: 0.712 ± 0.398
2.135GluLys: 2.135 ± 1.194
2.847GluLeu: 2.847 ± 1.592
1.423GluMet: 1.423 ± 0.796
1.423GluAsn: 1.423 ± 0.796
3.559GluPro: 3.559 ± 1.989
2.135GluGln: 2.135 ± 0.723
5.694GluArg: 5.694 ± 1.782
1.423GluSer: 1.423 ± 0.754
2.847GluThr: 2.847 ± 0.907
4.27GluVal: 4.27 ± 2.705
1.423GluTrp: 1.423 ± 1.131
1.423GluTyr: 1.423 ± 0.543
0.0GluXaa: 0.0 ± 0.0
Phe
3.559PheAla: 3.559 ± 1.25
0.0PheCys: 0.0 ± 0.0
3.559PheAsp: 3.559 ± 1.869
1.423PheGlu: 1.423 ± 0.796
0.0PhePhe: 0.0 ± 0.0
4.982PheGly: 4.982 ± 2.343
2.847PheHis: 2.847 ± 1.239
0.712PheIle: 0.712 ± 0.398
2.847PheLys: 2.847 ± 0.365
2.847PheLeu: 2.847 ± 0.907
0.712PheMet: 0.712 ± 0.965
0.712PheAsn: 0.712 ± 0.711
0.712PhePro: 0.712 ± 0.398
2.135PheGln: 2.135 ± 0.74
2.847PheArg: 2.847 ± 0.907
1.423PheSer: 1.423 ± 0.754
3.559PheThr: 3.559 ± 1.88
2.847PheVal: 2.847 ± 1.509
1.423PheTrp: 1.423 ± 0.754
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
8.541GlyAla: 8.541 ± 2.908
0.712GlyCys: 0.712 ± 0.398
4.27GlyAsp: 4.27 ± 1.512
2.135GlyGlu: 2.135 ± 0.74
3.559GlyPhe: 3.559 ± 1.315
7.829GlyGly: 7.829 ± 3.591
3.559GlyHis: 3.559 ± 1.869
4.982GlyIle: 4.982 ± 0.368
4.982GlyLys: 4.982 ± 1.998
9.964GlyLeu: 9.964 ± 1.032
1.423GlyMet: 1.423 ± 0.591
1.423GlyAsn: 1.423 ± 0.754
4.27GlyPro: 4.27 ± 1.266
3.559GlyGln: 3.559 ± 1.25
8.541GlyArg: 8.541 ± 4.526
3.559GlySer: 3.559 ± 1.315
2.847GlyThr: 2.847 ± 1.085
7.117GlyVal: 7.117 ± 1.735
2.847GlyTrp: 2.847 ± 1.085
1.423GlyTyr: 1.423 ± 0.796
0.0GlyXaa: 0.0 ± 0.0
His
3.559HisAla: 3.559 ± 1.315
0.712HisCys: 0.712 ± 0.398
0.712HisAsp: 0.712 ± 0.398
2.135HisGlu: 2.135 ± 1.979
1.423HisPhe: 1.423 ± 0.796
2.135HisGly: 2.135 ± 0.74
2.847HisHis: 2.847 ± 1.509
0.0HisIle: 0.0 ± 0.0
0.712HisLys: 0.712 ± 0.965
2.847HisLeu: 2.847 ± 0.365
0.0HisMet: 0.0 ± 0.0
0.712HisAsn: 0.712 ± 0.965
2.847HisPro: 2.847 ± 2.237
0.0HisGln: 0.0 ± 0.0
2.135HisArg: 2.135 ± 0.723
1.423HisSer: 1.423 ± 0.796
4.27HisThr: 4.27 ± 0.535
2.847HisVal: 2.847 ± 0.891
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.847IleAla: 2.847 ± 0.365
0.712IleCys: 0.712 ± 0.398
3.559IleAsp: 3.559 ± 1.175
4.27IleGlu: 4.27 ± 0.503
0.712IlePhe: 0.712 ± 0.711
4.982IleGly: 4.982 ± 1.513
1.423IleHis: 1.423 ± 0.796
2.135IleIle: 2.135 ± 0.633
2.847IleLys: 2.847 ± 1.592
1.423IleLeu: 1.423 ± 0.796
0.712IleMet: 0.712 ± 0.398
2.847IleAsn: 2.847 ± 1.085
2.135IlePro: 2.135 ± 0.633
2.135IleGln: 2.135 ± 1.194
3.559IleArg: 3.559 ± 1.25
3.559IleSer: 3.559 ± 1.722
0.0IleThr: 0.0 ± 0.0
2.135IleVal: 2.135 ± 1.2
0.0IleTrp: 0.0 ± 0.0
1.423IleTyr: 1.423 ± 0.796
0.0IleXaa: 0.0 ± 0.0
Lys
6.406LysAla: 6.406 ± 2.159
0.712LysCys: 0.712 ± 0.398
2.135LysAsp: 2.135 ± 1.194
2.135LysGlu: 2.135 ± 1.194
2.135LysPhe: 2.135 ± 0.633
4.982LysGly: 4.982 ± 0.888
0.712LysHis: 0.712 ± 0.398
0.712LysIle: 0.712 ± 0.398
3.559LysLys: 3.559 ± 1.722
6.406LysLeu: 6.406 ± 1.676
0.712LysMet: 0.712 ± 0.398
0.712LysAsn: 0.712 ± 0.398
0.712LysPro: 0.712 ± 0.711
0.0LysGln: 0.0 ± 0.0
3.559LysArg: 3.559 ± 0.187
2.135LysSer: 2.135 ± 0.633
0.712LysThr: 0.712 ± 0.398
0.712LysVal: 0.712 ± 0.398
0.712LysTrp: 0.712 ± 0.398
0.712LysTyr: 0.712 ± 0.398
0.0LysXaa: 0.0 ± 0.0
Leu
7.829LeuAla: 7.829 ± 1.385
3.559LeuCys: 3.559 ± 1.423
2.135LeuAsp: 2.135 ± 0.633
5.694LeuGlu: 5.694 ± 1.281
3.559LeuPhe: 3.559 ± 0.187
5.694LeuGly: 5.694 ± 1.815
2.135LeuHis: 2.135 ± 0.633
3.559LeuIle: 3.559 ± 1.989
1.423LeuLys: 1.423 ± 0.543
2.847LeuLeu: 2.847 ± 0.907
1.423LeuMet: 1.423 ± 1.036
3.559LeuAsn: 3.559 ± 1.25
4.27LeuPro: 4.27 ± 0.535
3.559LeuGln: 3.559 ± 0.187
5.694LeuArg: 5.694 ± 2.383
4.27LeuSer: 4.27 ± 0.503
5.694LeuThr: 5.694 ± 1.815
2.847LeuVal: 2.847 ± 0.907
0.0LeuTrp: 0.0 ± 0.0
3.559LeuTyr: 3.559 ± 1.989
0.0LeuXaa: 0.0 ± 0.0
Met
3.559MetAla: 3.559 ± 1.25
0.0MetCys: 0.0 ± 0.0
0.712MetAsp: 0.712 ± 0.398
1.423MetGlu: 1.423 ± 0.543
0.0MetPhe: 0.0 ± 0.0
0.712MetGly: 0.712 ± 0.965
0.712MetHis: 0.712 ± 0.711
2.135MetIle: 2.135 ± 0.633
0.0MetLys: 0.0 ± 0.0
1.423MetLeu: 1.423 ± 0.796
0.712MetMet: 0.712 ± 0.711
1.423MetAsn: 1.423 ± 1.421
1.423MetPro: 1.423 ± 0.543
0.712MetGln: 0.712 ± 0.398
2.135MetArg: 2.135 ± 1.2
2.847MetSer: 2.847 ± 0.907
0.0MetThr: 0.0 ± 0.0
2.847MetVal: 2.847 ± 0.365
0.712MetTrp: 0.712 ± 0.965
1.423MetTyr: 1.423 ± 1.93
0.0MetXaa: 0.0 ± 0.0
Asn
3.559AsnAla: 3.559 ± 0.868
0.0AsnCys: 0.0 ± 0.0
2.847AsnAsp: 2.847 ± 0.891
2.135AsnGlu: 2.135 ± 0.633
1.423AsnPhe: 1.423 ± 0.754
1.423AsnGly: 1.423 ± 1.421
0.0AsnHis: 0.0 ± 0.0
0.712AsnIle: 0.712 ± 0.398
0.712AsnLys: 0.712 ± 0.711
2.135AsnLeu: 2.135 ± 1.194
2.135AsnMet: 2.135 ± 0.633
0.0AsnAsn: 0.0 ± 0.0
0.712AsnPro: 0.712 ± 0.398
0.0AsnGln: 0.0 ± 0.0
1.423AsnArg: 1.423 ± 0.796
2.135AsnSer: 2.135 ± 1.2
2.135AsnThr: 2.135 ± 0.723
0.712AsnVal: 0.712 ± 0.398
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.694ProAla: 5.694 ± 3.471
0.712ProCys: 0.712 ± 0.965
3.559ProAsp: 3.559 ± 1.25
4.982ProGlu: 4.982 ± 1.872
1.423ProPhe: 1.423 ± 1.131
3.559ProGly: 3.559 ± 1.869
0.712ProHis: 0.712 ± 0.398
3.559ProIle: 3.559 ± 1.722
3.559ProLys: 3.559 ± 1.989
2.135ProLeu: 2.135 ± 1.2
2.135ProMet: 2.135 ± 0.633
0.0ProAsn: 0.0 ± 0.0
3.559ProPro: 3.559 ± 1.989
2.135ProGln: 2.135 ± 1.194
3.559ProArg: 3.559 ± 1.722
2.135ProSer: 2.135 ± 0.633
0.712ProThr: 0.712 ± 0.398
4.982ProVal: 4.982 ± 1.628
0.0ProTrp: 0.0 ± 0.0
1.423ProTyr: 1.423 ± 1.131
0.0ProXaa: 0.0 ± 0.0
Gln
2.135GlnAla: 2.135 ± 0.74
0.0GlnCys: 0.0 ± 0.0
0.712GlnAsp: 0.712 ± 0.398
1.423GlnGlu: 1.423 ± 0.796
2.135GlnPhe: 2.135 ± 0.723
2.847GlnGly: 2.847 ± 0.365
1.423GlnHis: 1.423 ± 0.754
0.712GlnIle: 0.712 ± 0.398
2.135GlnLys: 2.135 ± 0.633
4.982GlnLeu: 4.982 ± 1.513
0.712GlnMet: 0.712 ± 0.741
0.0GlnAsn: 0.0 ± 0.0
0.712GlnPro: 0.712 ± 0.398
2.847GlnGln: 2.847 ± 1.085
4.27GlnArg: 4.27 ± 1.447
3.559GlnSer: 3.559 ± 3.603
1.423GlnThr: 1.423 ± 0.543
4.27GlnVal: 4.27 ± 1.266
0.0GlnTrp: 0.0 ± 0.0
2.135GlnTyr: 2.135 ± 1.686
0.0GlnXaa: 0.0 ± 0.0
Arg
5.694ArgAla: 5.694 ± 3.183
3.559ArgCys: 3.559 ± 3.603
4.27ArgAsp: 4.27 ± 0.503
2.135ArgGlu: 2.135 ± 0.723
4.27ArgPhe: 4.27 ± 0.503
4.982ArgGly: 4.982 ± 1.998
3.559ArgHis: 3.559 ± 1.423
2.847ArgIle: 2.847 ± 0.891
2.847ArgLys: 2.847 ± 1.085
6.406ArgLeu: 6.406 ± 2.148
2.135ArgMet: 2.135 ± 1.2
2.135ArgAsn: 2.135 ± 1.194
4.982ArgPro: 4.982 ± 0.368
0.712ArgGln: 0.712 ± 0.398
7.117ArgArg: 7.117 ± 2.629
7.117ArgSer: 7.117 ± 2.545
2.135ArgThr: 2.135 ± 1.624
8.541ArgVal: 8.541 ± 1.828
2.847ArgTrp: 2.847 ± 1.509
0.712ArgTyr: 0.712 ± 0.398
0.0ArgXaa: 0.0 ± 0.0
Ser
7.829SerAla: 7.829 ± 2.708
2.847SerCys: 2.847 ± 1.509
5.694SerAsp: 5.694 ± 0.906
1.423SerGlu: 1.423 ± 0.796
2.847SerPhe: 2.847 ± 0.365
5.694SerGly: 5.694 ± 2.128
1.423SerHis: 1.423 ± 1.131
3.559SerIle: 3.559 ± 1.25
2.135SerLys: 2.135 ± 0.633
4.27SerLeu: 4.27 ± 1.48
1.423SerMet: 1.423 ± 1.421
2.135SerAsn: 2.135 ± 0.633
2.847SerPro: 2.847 ± 2.262
3.559SerGln: 3.559 ± 1.315
2.847SerArg: 2.847 ± 1.509
1.423SerSer: 1.423 ± 1.93
2.135SerThr: 2.135 ± 1.624
3.559SerVal: 3.559 ± 2.427
1.423SerTrp: 1.423 ± 0.796
0.712SerTyr: 0.712 ± 0.711
0.0SerXaa: 0.0 ± 0.0
Thr
2.847ThrAla: 2.847 ± 1.592
3.559ThrCys: 3.559 ± 1.25
2.135ThrAsp: 2.135 ± 0.723
2.135ThrGlu: 2.135 ± 0.633
3.559ThrPhe: 3.559 ± 1.315
2.847ThrGly: 2.847 ± 1.239
1.423ThrHis: 1.423 ± 1.131
3.559ThrIle: 3.559 ± 1.25
1.423ThrLys: 1.423 ± 0.796
2.847ThrLeu: 2.847 ± 0.907
0.712ThrMet: 0.712 ± 0.711
0.712ThrAsn: 0.712 ± 0.398
2.135ThrPro: 2.135 ± 1.2
4.27ThrGln: 4.27 ± 1.053
6.406ThrArg: 6.406 ± 3.021
2.847ThrSer: 2.847 ± 1.239
7.117ThrThr: 7.117 ± 1.536
0.712ThrVal: 0.712 ± 0.711
0.712ThrTrp: 0.712 ± 0.711
1.423ThrTyr: 1.423 ± 0.796
0.0ThrXaa: 0.0 ± 0.0
Val
7.117ValAla: 7.117 ± 2.22
0.712ValCys: 0.712 ± 0.398
4.27ValAsp: 4.27 ± 0.535
4.982ValGlu: 4.982 ± 2.785
2.847ValPhe: 2.847 ± 1.632
7.829ValGly: 7.829 ± 1.457
1.423ValHis: 1.423 ± 0.754
2.847ValIle: 2.847 ± 1.085
2.847ValLys: 2.847 ± 0.365
2.135ValLeu: 2.135 ± 0.74
2.847ValMet: 2.847 ± 0.907
1.423ValAsn: 1.423 ± 0.754
4.982ValPro: 4.982 ± 1.914
2.135ValGln: 2.135 ± 1.979
3.559ValArg: 3.559 ± 1.25
4.27ValSer: 4.27 ± 0.503
3.559ValThr: 3.559 ± 1.11
2.847ValVal: 2.847 ± 1.085
2.135ValTrp: 2.135 ± 1.624
0.712ValTyr: 0.712 ± 0.398
0.0ValXaa: 0.0 ± 0.0
Trp
2.135TrpAla: 2.135 ± 0.723
0.712TrpCys: 0.712 ± 0.965
1.423TrpAsp: 1.423 ± 0.754
0.712TrpGlu: 0.712 ± 0.711
0.712TrpPhe: 0.712 ± 0.965
1.423TrpGly: 1.423 ± 1.131
0.712TrpHis: 0.712 ± 0.398
0.0TrpIle: 0.0 ± 0.0
0.712TrpLys: 0.712 ± 0.398
1.423TrpLeu: 1.423 ± 0.796
0.712TrpMet: 0.712 ± 0.398
0.712TrpAsn: 0.712 ± 0.711
0.0TrpPro: 0.0 ± 0.0
0.712TrpGln: 0.712 ± 0.398
2.135TrpArg: 2.135 ± 0.633
1.423TrpSer: 1.423 ± 1.93
0.712TrpThr: 0.712 ± 0.398
2.135TrpVal: 2.135 ± 0.723
0.0TrpTrp: 0.0 ± 0.0
1.423TrpTyr: 1.423 ± 1.421
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.712TyrAla: 0.712 ± 0.398
0.0TyrCys: 0.0 ± 0.0
1.423TyrAsp: 1.423 ± 0.754
2.847TyrGlu: 2.847 ± 0.891
1.423TyrPhe: 1.423 ± 0.543
2.135TyrGly: 2.135 ± 0.723
0.712TyrHis: 0.712 ± 0.711
0.712TyrIle: 0.712 ± 0.398
0.0TyrLys: 0.0 ± 0.0
2.135TyrLeu: 2.135 ± 1.194
0.712TyrMet: 0.712 ± 0.965
0.712TyrAsn: 0.712 ± 0.398
0.712TyrPro: 0.712 ± 0.398
1.423TyrGln: 1.423 ± 1.131
1.423TyrArg: 1.423 ± 0.796
3.559TyrSer: 3.559 ± 1.315
0.712TyrThr: 0.712 ± 0.711
0.712TyrVal: 0.712 ± 0.398
0.712TyrTrp: 0.712 ± 0.398
0.712TyrTyr: 0.712 ± 0.398
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1406 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski