Amino acid dipepetide frequency for Gilliamella apicola SCGC AB-598-B02

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.809AlaAla: 4.809 ± 0.122
0.834AlaCys: 0.834 ± 0.044
3.52AlaAsp: 3.52 ± 0.087
3.853AlaGlu: 3.853 ± 0.108
3.025AlaPhe: 3.025 ± 0.094
4.441AlaGly: 4.441 ± 0.113
1.233AlaHis: 1.233 ± 0.051
6.508AlaIle: 6.508 ± 0.139
4.912AlaLys: 4.912 ± 0.103
7.484AlaLeu: 7.484 ± 0.15
1.893AlaMet: 1.893 ± 0.06
3.756AlaAsn: 3.756 ± 0.095
2.063AlaPro: 2.063 ± 0.071
2.968AlaGln: 2.968 ± 0.101
2.6AlaArg: 2.6 ± 0.075
4.09AlaSer: 4.09 ± 0.095
3.746AlaThr: 3.746 ± 0.099
4.34AlaVal: 4.34 ± 0.11
0.715AlaTrp: 0.715 ± 0.042
2.281AlaTyr: 2.281 ± 0.071
0.0AlaXaa: 0.0 ± 0.0
Cys
0.792CysAla: 0.792 ± 0.04
0.214CysCys: 0.214 ± 0.024
0.608CysAsp: 0.608 ± 0.039
0.548CysGlu: 0.548 ± 0.039
0.659CysPhe: 0.659 ± 0.033
0.847CysGly: 0.847 ± 0.043
0.343CysHis: 0.343 ± 0.029
0.897CysIle: 0.897 ± 0.041
0.544CysLys: 0.544 ± 0.036
1.186CysLeu: 1.186 ± 0.055
0.2CysMet: 0.2 ± 0.018
0.513CysAsn: 0.513 ± 0.035
0.493CysPro: 0.493 ± 0.032
0.612CysGln: 0.612 ± 0.036
0.434CysArg: 0.434 ± 0.027
0.719CysSer: 0.719 ± 0.045
0.475CysThr: 0.475 ± 0.032
0.61CysVal: 0.61 ± 0.041
0.158CysTrp: 0.158 ± 0.019
0.582CysTyr: 0.582 ± 0.036
0.0CysXaa: 0.0 ± 0.0
Asp
3.287AspAla: 3.287 ± 0.085
0.624AspCys: 0.624 ± 0.038
2.976AspAsp: 2.976 ± 0.09
3.738AspGlu: 3.738 ± 0.086
2.564AspPhe: 2.564 ± 0.081
3.035AspGly: 3.035 ± 0.094
0.956AspHis: 0.956 ± 0.046
4.977AspIle: 4.977 ± 0.094
4.178AspLys: 4.178 ± 0.096
5.162AspLeu: 5.162 ± 0.115
1.273AspMet: 1.273 ± 0.047
3.457AspAsn: 3.457 ± 0.085
1.875AspPro: 1.875 ± 0.06
1.75AspGln: 1.75 ± 0.069
2.067AspArg: 2.067 ± 0.064
3.13AspSer: 3.13 ± 0.077
2.352AspThr: 2.352 ± 0.063
3.231AspVal: 3.231 ± 0.085
0.715AspTrp: 0.715 ± 0.038
2.408AspTyr: 2.408 ± 0.069
0.0AspXaa: 0.0 ± 0.0
Glu
3.534GluAla: 3.534 ± 0.109
0.467GluCys: 0.467 ± 0.032
2.623GluAsp: 2.623 ± 0.075
3.051GluGlu: 3.051 ± 0.104
2.35GluPhe: 2.35 ± 0.072
2.641GluGly: 2.641 ± 0.078
1.362GluHis: 1.362 ± 0.062
4.74GluIle: 4.74 ± 0.09
4.538GluLys: 4.538 ± 0.115
6.411GluLeu: 6.411 ± 0.141
1.473GluMet: 1.473 ± 0.057
3.346GluAsn: 3.346 ± 0.09
1.78GluPro: 1.78 ± 0.053
3.653GluGln: 3.653 ± 0.124
2.477GluArg: 2.477 ± 0.071
3.219GluSer: 3.219 ± 0.085
2.588GluThr: 2.588 ± 0.075
3.382GluVal: 3.382 ± 0.087
0.669GluTrp: 0.669 ± 0.037
1.827GluTyr: 1.827 ± 0.067
0.0GluXaa: 0.0 ± 0.0
Phe
3.158PheAla: 3.158 ± 0.095
0.669PheCys: 0.669 ± 0.038
2.776PheAsp: 2.776 ± 0.072
2.279PheGlu: 2.279 ± 0.08
2.166PhePhe: 2.166 ± 0.08
2.863PheGly: 2.863 ± 0.077
0.796PheHis: 0.796 ± 0.041
4.233PheIle: 4.233 ± 0.111
2.673PheLys: 2.673 ± 0.084
3.898PheLeu: 3.898 ± 0.1
1.03PheMet: 1.03 ± 0.041
2.912PheAsn: 2.912 ± 0.087
1.471PhePro: 1.471 ± 0.047
1.289PheGln: 1.289 ± 0.055
1.35PheArg: 1.35 ± 0.059
3.326PheSer: 3.326 ± 0.083
2.485PheThr: 2.485 ± 0.079
2.714PheVal: 2.714 ± 0.085
0.544PheTrp: 0.544 ± 0.031
1.867PheTyr: 1.867 ± 0.06
0.0PheXaa: 0.0 ± 0.0
Gly
3.974GlyAla: 3.974 ± 0.11
0.867GlyCys: 0.867 ± 0.047
3.075GlyAsp: 3.075 ± 0.089
3.247GlyGlu: 3.247 ± 0.082
3.019GlyPhe: 3.019 ± 0.086
3.988GlyGly: 3.988 ± 0.118
1.356GlyHis: 1.356 ± 0.055
5.35GlyIle: 5.35 ± 0.126
4.029GlyLys: 4.029 ± 0.101
5.993GlyLeu: 5.993 ± 0.132
1.651GlyMet: 1.651 ± 0.062
2.897GlyAsn: 2.897 ± 0.098
1.311GlyPro: 1.311 ± 0.054
2.289GlyGln: 2.289 ± 0.068
2.364GlyArg: 2.364 ± 0.067
3.617GlySer: 3.617 ± 0.091
2.992GlyThr: 2.992 ± 0.088
4.166GlyVal: 4.166 ± 0.092
0.863GlyTrp: 0.863 ± 0.041
2.691GlyTyr: 2.691 ± 0.073
0.0GlyXaa: 0.0 ± 0.0
His
1.271HisAla: 1.271 ± 0.051
0.38HisCys: 0.38 ± 0.028
1.039HisAsp: 1.039 ± 0.046
1.0HisGlu: 1.0 ± 0.042
1.075HisPhe: 1.075 ± 0.046
1.279HisGly: 1.279 ± 0.061
0.655HisHis: 0.655 ± 0.038
1.6HisIle: 1.6 ± 0.055
1.131HisLys: 1.131 ± 0.046
2.204HisLeu: 2.204 ± 0.072
0.396HisMet: 0.396 ± 0.03
1.152HisAsn: 1.152 ± 0.048
0.948HisPro: 0.948 ± 0.046
1.014HisGln: 1.014 ± 0.052
0.849HisArg: 0.849 ± 0.046
1.317HisSer: 1.317 ± 0.046
0.966HisThr: 0.966 ± 0.046
1.107HisVal: 1.107 ± 0.052
0.281HisTrp: 0.281 ± 0.022
1.085HisTyr: 1.085 ± 0.052
0.0HisXaa: 0.0 ± 0.0
Ile
7.001IleAla: 7.001 ± 0.154
1.061IleCys: 1.061 ± 0.047
5.544IleAsp: 5.544 ± 0.105
5.651IleGlu: 5.651 ± 0.112
3.617IlePhe: 3.617 ± 0.1
5.534IleGly: 5.534 ± 0.125
1.521IleHis: 1.521 ± 0.053
7.33IleIle: 7.33 ± 0.162
5.797IleLys: 5.797 ± 0.114
7.646IleLeu: 7.646 ± 0.16
1.859IleMet: 1.859 ± 0.064
5.34IleAsn: 5.34 ± 0.13
3.324IlePro: 3.324 ± 0.088
2.613IleGln: 2.613 ± 0.079
2.998IleArg: 2.998 ± 0.073
5.823IleSer: 5.823 ± 0.11
5.122IleThr: 5.122 ± 0.11
5.067IleVal: 5.067 ± 0.11
0.818IleTrp: 0.818 ± 0.045
2.932IleTyr: 2.932 ± 0.079
0.0IleXaa: 0.0 ± 0.0
Lys
4.378LysAla: 4.378 ± 0.114
0.42LysCys: 0.42 ± 0.028
3.409LysAsp: 3.409 ± 0.093
3.829LysGlu: 3.829 ± 0.09
2.154LysPhe: 2.154 ± 0.075
3.528LysGly: 3.528 ± 0.094
1.338LysHis: 1.338 ± 0.054
5.7LysIle: 5.7 ± 0.112
5.011LysLys: 5.011 ± 0.117
6.736LysLeu: 6.736 ± 0.112
1.732LysMet: 1.732 ± 0.058
4.055LysAsn: 4.055 ± 0.098
2.445LysPro: 2.445 ± 0.079
4.324LysGln: 4.324 ± 0.111
2.843LysArg: 2.843 ± 0.08
3.908LysSer: 3.908 ± 0.087
3.898LysThr: 3.898 ± 0.102
4.102LysVal: 4.102 ± 0.1
0.659LysTrp: 0.659 ± 0.042
2.421LysTyr: 2.421 ± 0.077
0.0LysXaa: 0.0 ± 0.0
Leu
7.975LeuAla: 7.975 ± 0.147
1.182LeuCys: 1.182 ± 0.05
5.393LeuAsp: 5.393 ± 0.109
5.17LeuGlu: 5.17 ± 0.108
4.906LeuPhe: 4.906 ± 0.124
6.219LeuGly: 6.219 ± 0.139
1.794LeuHis: 1.794 ± 0.063
8.587LeuIle: 8.587 ± 0.156
6.516LeuLys: 6.516 ± 0.125
10.537LeuLeu: 10.537 ± 0.197
2.425LeuMet: 2.425 ± 0.08
6.005LeuAsn: 6.005 ± 0.119
4.544LeuPro: 4.544 ± 0.104
3.782LeuGln: 3.782 ± 0.092
3.738LeuArg: 3.738 ± 0.096
7.937LeuSer: 7.937 ± 0.137
6.253LeuThr: 6.253 ± 0.124
5.971LeuVal: 5.971 ± 0.129
1.109LeuTrp: 1.109 ± 0.05
3.079LeuTyr: 3.079 ± 0.091
0.0LeuXaa: 0.0 ± 0.0
Met
1.798MetAla: 1.798 ± 0.053
0.184MetCys: 0.184 ± 0.018
1.059MetAsp: 1.059 ± 0.052
1.004MetGlu: 1.004 ± 0.043
0.883MetPhe: 0.883 ± 0.047
1.499MetGly: 1.499 ± 0.067
0.473MetHis: 0.473 ± 0.026
2.01MetIle: 2.01 ± 0.063
1.606MetLys: 1.606 ± 0.05
2.594MetLeu: 2.594 ± 0.078
0.721MetMet: 0.721 ± 0.044
1.21MetAsn: 1.21 ± 0.051
1.186MetPro: 1.186 ± 0.041
1.164MetGln: 1.164 ± 0.051
0.942MetArg: 0.942 ± 0.048
1.671MetSer: 1.671 ± 0.056
1.451MetThr: 1.451 ± 0.052
1.661MetVal: 1.661 ± 0.062
0.218MetTrp: 0.218 ± 0.023
0.578MetTyr: 0.578 ± 0.042
0.0MetXaa: 0.0 ± 0.0
Asn
3.473AsnAla: 3.473 ± 0.084
0.594AsnCys: 0.594 ± 0.039
3.279AsnAsp: 3.279 ± 0.086
3.471AsnGlu: 3.471 ± 0.089
2.105AsnPhe: 2.105 ± 0.076
3.302AsnGly: 3.302 ± 0.126
1.426AsnHis: 1.426 ± 0.054
5.003AsnIle: 5.003 ± 0.118
4.197AsnLys: 4.197 ± 0.107
5.387AsnLeu: 5.387 ± 0.13
1.267AsnMet: 1.267 ± 0.051
4.09AsnAsn: 4.09 ± 0.147
2.313AsnPro: 2.313 ± 0.085
2.978AsnGln: 2.978 ± 0.082
2.255AsnArg: 2.255 ± 0.066
3.603AsnSer: 3.603 ± 0.083
2.627AsnThr: 2.627 ± 0.089
3.015AsnVal: 3.015 ± 0.096
0.748AsnTrp: 0.748 ± 0.043
2.471AsnTyr: 2.471 ± 0.08
0.0AsnXaa: 0.0 ± 0.0
Pro
2.485ProAla: 2.485 ± 0.083
0.386ProCys: 0.386 ± 0.028
2.099ProAsp: 2.099 ± 0.065
2.56ProGlu: 2.56 ± 0.076
1.82ProPhe: 1.82 ± 0.06
1.538ProGly: 1.538 ± 0.055
0.721ProHis: 0.721 ± 0.039
3.116ProIle: 3.116 ± 0.089
2.489ProLys: 2.489 ± 0.087
3.831ProLeu: 3.831 ± 0.084
0.861ProMet: 0.861 ± 0.043
2.344ProAsn: 2.344 ± 0.074
0.95ProPro: 0.95 ± 0.041
1.431ProGln: 1.431 ± 0.05
1.079ProArg: 1.079 ± 0.045
2.146ProSer: 2.146 ± 0.059
2.063ProThr: 2.063 ± 0.098
2.467ProVal: 2.467 ± 0.086
0.43ProTrp: 0.43 ± 0.03
1.469ProTyr: 1.469 ± 0.057
0.0ProXaa: 0.0 ± 0.0
Gln
3.378GlnAla: 3.378 ± 0.091
0.451GlnCys: 0.451 ± 0.033
2.004GlnAsp: 2.004 ± 0.076
2.443GlnGlu: 2.443 ± 0.079
1.893GlnPhe: 1.893 ± 0.063
2.313GlnGly: 2.313 ± 0.065
0.958GlnHis: 0.958 ± 0.043
3.728GlnIle: 3.728 ± 0.09
2.942GlnLys: 2.942 ± 0.089
5.419GlnLeu: 5.419 ± 0.118
0.942GlnMet: 0.942 ± 0.048
2.495GlnAsn: 2.495 ± 0.087
1.485GlnPro: 1.485 ± 0.061
2.897GlnGln: 2.897 ± 0.1
1.752GlnArg: 1.752 ± 0.065
2.655GlnSer: 2.655 ± 0.081
2.358GlnThr: 2.358 ± 0.082
2.507GlnVal: 2.507 ± 0.068
0.497GlnTrp: 0.497 ± 0.03
1.847GlnTyr: 1.847 ± 0.061
0.0GlnXaa: 0.0 ± 0.0
Arg
2.461ArgAla: 2.461 ± 0.077
0.416ArgCys: 0.416 ± 0.033
1.901ArgAsp: 1.901 ± 0.061
2.283ArgGlu: 2.283 ± 0.077
1.924ArgPhe: 1.924 ± 0.057
2.023ArgGly: 2.023 ± 0.069
0.901ArgHis: 0.901 ± 0.041
3.15ArgIle: 3.15 ± 0.078
2.58ArgLys: 2.58 ± 0.072
3.97ArgLeu: 3.97 ± 0.092
0.885ArgMet: 0.885 ± 0.038
1.956ArgAsn: 1.956 ± 0.065
1.334ArgPro: 1.334 ± 0.048
1.911ArgGln: 1.911 ± 0.069
1.782ArgArg: 1.782 ± 0.062
2.277ArgSer: 2.277 ± 0.077
1.794ArgThr: 1.794 ± 0.065
2.316ArgVal: 2.316 ± 0.07
0.467ArgTrp: 0.467 ± 0.034
1.859ArgTyr: 1.859 ± 0.075
0.0ArgXaa: 0.0 ± 0.0
Ser
4.269SerAla: 4.269 ± 0.107
0.673SerCys: 0.673 ± 0.04
3.5SerAsp: 3.5 ± 0.075
3.437SerGlu: 3.437 ± 0.092
3.055SerPhe: 3.055 ± 0.091
4.162SerGly: 4.162 ± 0.097
1.386SerHis: 1.386 ± 0.049
5.597SerIle: 5.597 ± 0.118
3.91SerLys: 3.91 ± 0.085
6.973SerLeu: 6.973 ± 0.118
1.483SerMet: 1.483 ± 0.062
3.374SerAsn: 3.374 ± 0.089
2.249SerPro: 2.249 ± 0.073
2.865SerGln: 2.865 ± 0.088
2.471SerArg: 2.471 ± 0.079
4.405SerSer: 4.405 ± 0.112
3.293SerThr: 3.293 ± 0.094
3.918SerVal: 3.918 ± 0.095
0.752SerTrp: 0.752 ± 0.041
2.546SerTyr: 2.546 ± 0.075
0.0SerXaa: 0.0 ± 0.0
Thr
3.453ThrAla: 3.453 ± 0.096
0.539ThrCys: 0.539 ± 0.034
2.944ThrAsp: 2.944 ± 0.076
3.019ThrGlu: 3.019 ± 0.075
2.257ThrPhe: 2.257 ± 0.058
3.489ThrGly: 3.489 ± 0.096
1.182ThrHis: 1.182 ± 0.057
4.72ThrIle: 4.72 ± 0.105
3.184ThrLys: 3.184 ± 0.086
5.928ThrLeu: 5.928 ± 0.09
1.162ThrMet: 1.162 ± 0.058
2.853ThrAsn: 2.853 ± 0.119
2.427ThrPro: 2.427 ± 0.072
2.368ThrGln: 2.368 ± 0.071
1.808ThrArg: 1.808 ± 0.062
3.316ThrSer: 3.316 ± 0.091
2.885ThrThr: 2.885 ± 0.096
3.471ThrVal: 3.471 ± 0.085
0.541ThrTrp: 0.541 ± 0.036
1.604ThrTyr: 1.604 ± 0.062
0.0ThrXaa: 0.0 ± 0.0
Val
4.479ValAla: 4.479 ± 0.103
0.731ValCys: 0.731 ± 0.037
3.457ValAsp: 3.457 ± 0.09
3.467ValGlu: 3.467 ± 0.088
2.546ValPhe: 2.546 ± 0.079
4.134ValGly: 4.134 ± 0.105
1.0ValHis: 1.0 ± 0.046
5.591ValIle: 5.591 ± 0.093
4.061ValLys: 4.061 ± 0.102
5.868ValLeu: 5.868 ± 0.121
1.641ValMet: 1.641 ± 0.053
3.471ValAsn: 3.471 ± 0.101
2.156ValPro: 2.156 ± 0.066
1.681ValGln: 1.681 ± 0.06
2.095ValArg: 2.095 ± 0.079
4.132ValSer: 4.132 ± 0.078
3.645ValThr: 3.645 ± 0.103
3.972ValVal: 3.972 ± 0.115
0.59ValTrp: 0.59 ± 0.036
1.915ValTyr: 1.915 ± 0.064
0.0ValXaa: 0.0 ± 0.0
Trp
0.651TrpAla: 0.651 ± 0.035
0.145TrpCys: 0.145 ± 0.018
0.515TrpAsp: 0.515 ± 0.034
0.428TrpGlu: 0.428 ± 0.029
0.604TrpPhe: 0.604 ± 0.04
0.683TrpGly: 0.683 ± 0.043
0.315TrpHis: 0.315 ± 0.024
0.919TrpIle: 0.919 ± 0.049
0.57TrpLys: 0.57 ± 0.031
1.572TrpLeu: 1.572 ± 0.064
0.315TrpMet: 0.315 ± 0.024
0.481TrpAsn: 0.481 ± 0.028
0.384TrpPro: 0.384 ± 0.029
0.974TrpGln: 0.974 ± 0.047
0.554TrpArg: 0.554 ± 0.042
0.659TrpSer: 0.659 ± 0.039
0.434TrpThr: 0.434 ± 0.028
0.681TrpVal: 0.681 ± 0.032
0.119TrpTrp: 0.119 ± 0.016
0.453TrpTyr: 0.453 ± 0.041
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.443TyrAla: 2.443 ± 0.081
0.596TyrCys: 0.596 ± 0.038
2.035TyrAsp: 2.035 ± 0.079
1.651TyrGlu: 1.651 ± 0.056
1.877TyrPhe: 1.877 ± 0.07
2.223TyrGly: 2.223 ± 0.065
1.032TyrHis: 1.032 ± 0.047
2.843TyrIle: 2.843 ± 0.087
2.018TyrLys: 2.018 ± 0.069
4.324TyrLeu: 4.324 ± 0.106
0.705TyrMet: 0.705 ± 0.035
1.895TyrAsn: 1.895 ± 0.07
1.548TyrPro: 1.548 ± 0.052
2.4TyrGln: 2.4 ± 0.069
1.732TyrArg: 1.732 ± 0.066
2.37TyrSer: 2.37 ± 0.077
1.723TyrThr: 1.723 ± 0.071
1.936TyrVal: 1.936 ± 0.067
0.564TyrTrp: 0.564 ± 0.049
1.586TyrTyr: 1.586 ± 0.066
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1967 proteins (494925 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski