Amino acid dipepetide frequency for Luteipulveratus halotolerans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.067AlaAla: 19.067 ± 0.181	1.003AlaCys: 1.003 ± 0.034	8.739AlaAsp: 8.739 ± 0.091	7.214AlaGlu: 7.214 ± 0.103	3.359AlaPhe: 3.359 ± 0.058	11.797AlaGly: 11.797 ± 0.119	2.78AlaHis: 2.78 ± 0.055	4.251AlaIle: 4.251 ± 0.056	2.768AlaLys: 2.768 ± 0.064	13.417AlaLeu: 13.417 ± 0.154	2.975AlaMet: 2.975 ± 0.051	1.782AlaAsn: 1.782 ± 0.041	6.053AlaPro: 6.053 ± 0.077	4.244AlaGln: 4.244 ± 0.062	9.392AlaArg: 9.392 ± 0.105	6.877AlaSer: 6.877 ± 0.079	7.572AlaThr: 7.572 ± 0.087	11.662AlaVal: 11.662 ± 0.14	1.908AlaTrp: 1.908 ± 0.045	3.004AlaTyr: 3.004 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.9CysAla: 0.9 ± 0.028	0.092CysCys: 0.092 ± 0.008	0.496CysAsp: 0.496 ± 0.02	0.359CysGlu: 0.359 ± 0.016	0.235CysPhe: 0.235 ± 0.014	0.846CysGly: 0.846 ± 0.028	0.183CysHis: 0.183 ± 0.013	0.221CysIle: 0.221 ± 0.013	0.125CysLys: 0.125 ± 0.01	0.636CysLeu: 0.636 ± 0.023	0.117CysMet: 0.117 ± 0.01	0.132CysAsn: 0.132 ± 0.012	0.453CysPro: 0.453 ± 0.024	0.195CysGln: 0.195 ± 0.012	0.482CysArg: 0.482 ± 0.022	0.444CysSer: 0.444 ± 0.02	0.466CysThr: 0.466 ± 0.021	0.613CysVal: 0.613 ± 0.026	0.107CysTrp: 0.107 ± 0.009	0.159CysTyr: 0.159 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.485AspAla: 8.485 ± 0.086	0.36AspCys: 0.36 ± 0.022	5.108AspAsp: 5.108 ± 0.079	4.734AspGlu: 4.734 ± 0.073	1.48AspPhe: 1.48 ± 0.038	6.493AspGly: 6.493 ± 0.084	1.588AspHis: 1.588 ± 0.043	2.13AspIle: 2.13 ± 0.049	1.43AspLys: 1.43 ± 0.042	7.205AspLeu: 7.205 ± 0.101	0.954AspMet: 0.954 ± 0.026	1.122AspAsn: 1.122 ± 0.032	4.242AspPro: 4.242 ± 0.066	2.134AspGln: 2.134 ± 0.047	5.035AspArg: 5.035 ± 0.073	2.64AspSer: 2.64 ± 0.058	2.966AspThr: 2.966 ± 0.049	6.328AspVal: 6.328 ± 0.087	0.962AspTrp: 0.962 ± 0.029	1.202AspTyr: 1.202 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.59GluAla: 6.59 ± 0.084	0.353GluCys: 0.353 ± 0.018	2.664GluAsp: 2.664 ± 0.056	2.449GluGlu: 2.449 ± 0.06	1.301GluPhe: 1.301 ± 0.035	4.091GluGly: 4.091 ± 0.071	1.868GluHis: 1.868 ± 0.046	2.258GluIle: 2.258 ± 0.049	1.225GluLys: 1.225 ± 0.04	5.973GluLeu: 5.973 ± 0.071	1.034GluMet: 1.034 ± 0.032	0.716GluAsn: 0.716 ± 0.024	3.15GluPro: 3.15 ± 0.053	2.771GluGln: 2.771 ± 0.056	5.315GluArg: 5.315 ± 0.083	2.857GluSer: 2.857 ± 0.05	2.817GluThr: 2.817 ± 0.049	5.048GluVal: 5.048 ± 0.063	0.781GluTrp: 0.781 ± 0.029	0.876GluTyr: 0.876 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	3.443PheAla: 3.443 ± 0.066	0.235PheCys: 0.235 ± 0.014	1.953PheAsp: 1.953 ± 0.043	1.444PheGlu: 1.444 ± 0.035	0.87PhePhe: 0.87 ± 0.032	2.986PheGly: 2.986 ± 0.052	0.557PheHis: 0.557 ± 0.022	0.8PheIle: 0.8 ± 0.025	0.521PheLys: 0.521 ± 0.025	2.216PheLeu: 2.216 ± 0.046	0.404PheMet: 0.404 ± 0.019	0.585PheAsn: 0.585 ± 0.023	1.173PhePro: 1.173 ± 0.038	0.575PheGln: 0.575 ± 0.023	1.527PheArg: 1.527 ± 0.034	1.362PheSer: 1.362 ± 0.032	1.798PheThr: 1.798 ± 0.044	2.655PheVal: 2.655 ± 0.044	0.418PheTrp: 0.418 ± 0.022	0.606PheTyr: 0.606 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	10.335GlyAla: 10.335 ± 0.11	0.752GlyCys: 0.752 ± 0.029	5.388GlyAsp: 5.388 ± 0.08	4.856GlyGlu: 4.856 ± 0.065	2.799GlyPhe: 2.799 ± 0.054	7.919GlyGly: 7.919 ± 0.128	2.141GlyHis: 2.141 ± 0.048	3.377GlyIle: 3.377 ± 0.057	2.307GlyLys: 2.307 ± 0.055	9.163GlyLeu: 9.163 ± 0.097	1.99GlyMet: 1.99 ± 0.045	1.597GlyAsn: 1.597 ± 0.043	4.151GlyPro: 4.151 ± 0.056	2.874GlyGln: 2.874 ± 0.059	7.094GlyArg: 7.094 ± 0.075	5.674GlySer: 5.674 ± 0.079	5.444GlyThr: 5.444 ± 0.068	8.05GlyVal: 8.05 ± 0.093	1.787GlyTrp: 1.787 ± 0.041	2.099GlyTyr: 2.099 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.606HisAla: 2.606 ± 0.054	0.172HisCys: 0.172 ± 0.012	1.792HisAsp: 1.792 ± 0.039	1.494HisGlu: 1.494 ± 0.036	0.546HisPhe: 0.546 ± 0.023	2.33HisGly: 2.33 ± 0.057	0.702HisHis: 0.702 ± 0.027	0.632HisIle: 0.632 ± 0.025	0.378HisLys: 0.378 ± 0.018	2.504HisLeu: 2.504 ± 0.05	0.32HisMet: 0.32 ± 0.017	0.399HisAsn: 0.399 ± 0.022	1.519HisPro: 1.519 ± 0.043	0.696HisGln: 0.696 ± 0.024	1.951HisArg: 1.951 ± 0.046	0.989HisSer: 0.989 ± 0.028	1.154HisThr: 1.154 ± 0.033	2.086HisVal: 2.086 ± 0.043	0.341HisTrp: 0.341 ± 0.019	0.445HisTyr: 0.445 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.316IleAla: 5.316 ± 0.08	0.307IleCys: 0.307 ± 0.016	2.892IleAsp: 2.892 ± 0.05	2.252IleGlu: 2.252 ± 0.058	0.85IlePhe: 0.85 ± 0.03	3.989IleGly: 3.989 ± 0.064	0.621IleHis: 0.621 ± 0.02	1.126IleIle: 1.126 ± 0.039	0.839IleLys: 0.839 ± 0.033	2.284IleLeu: 2.284 ± 0.041	0.513IleMet: 0.513 ± 0.021	0.816IleAsn: 0.816 ± 0.03	1.74IlePro: 1.74 ± 0.042	0.808IleGln: 0.808 ± 0.028	2.258IleArg: 2.258 ± 0.05	2.005IleSer: 2.005 ± 0.038	2.485IleThr: 2.485 ± 0.049	3.002IleVal: 3.002 ± 0.055	0.411IleTrp: 0.411 ± 0.02	0.624IleTyr: 0.624 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.047LysAla: 3.047 ± 0.066	0.101LysCys: 0.101 ± 0.01	1.494LysAsp: 1.494 ± 0.041	1.02LysGlu: 1.02 ± 0.033	0.472LysPhe: 0.472 ± 0.022	1.901LysGly: 1.901 ± 0.048	0.508LysHis: 0.508 ± 0.023	0.889LysIle: 0.889 ± 0.037	0.89LysLys: 0.89 ± 0.041	1.457LysLeu: 1.457 ± 0.039	0.408LysMet: 0.408 ± 0.019	0.523LysAsn: 0.523 ± 0.024	1.373LysPro: 1.373 ± 0.045	0.76LysGln: 0.76 ± 0.029	1.41LysArg: 1.41 ± 0.034	1.173LysSer: 1.173 ± 0.039	1.339LysThr: 1.339 ± 0.039	2.18LysVal: 2.18 ± 0.047	0.253LysTrp: 0.253 ± 0.014	0.458LysTyr: 0.458 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.045LeuAla: 14.045 ± 0.164	0.67LeuCys: 0.67 ± 0.026	7.127LeuAsp: 7.127 ± 0.083	4.598LeuGlu: 4.598 ± 0.072	2.224LeuPhe: 2.224 ± 0.048	8.963LeuGly: 8.963 ± 0.116	2.08LeuHis: 2.08 ± 0.046	3.475LeuIle: 3.475 ± 0.067	1.992LeuLys: 1.992 ± 0.049	10.131LeuLeu: 10.131 ± 0.152	1.846LeuMet: 1.846 ± 0.042	1.608LeuAsn: 1.608 ± 0.044	5.56LeuPro: 5.56 ± 0.069	2.666LeuGln: 2.666 ± 0.051	7.972LeuArg: 7.972 ± 0.097	5.526LeuSer: 5.526 ± 0.073	6.554LeuThr: 6.554 ± 0.085	9.755LeuVal: 9.755 ± 0.119	1.196LeuTrp: 1.196 ± 0.034	1.478LeuTyr: 1.478 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	2.372MetAla: 2.372 ± 0.04	0.151MetCys: 0.151 ± 0.013	0.852MetAsp: 0.852 ± 0.025	0.7MetGlu: 0.7 ± 0.026	0.535MetPhe: 0.535 ± 0.024	1.389MetGly: 1.389 ± 0.035	0.423MetHis: 0.423 ± 0.019	0.742MetIle: 0.742 ± 0.027	0.481MetLys: 0.481 ± 0.021	2.007MetLeu: 2.007 ± 0.049	0.315MetMet: 0.315 ± 0.016	0.43MetAsn: 0.43 ± 0.02	1.205MetPro: 1.205 ± 0.029	0.596MetGln: 0.596 ± 0.026	1.566MetArg: 1.566 ± 0.033	1.664MetSer: 1.664 ± 0.042	1.849MetThr: 1.849 ± 0.039	1.578MetVal: 1.578 ± 0.03	0.231MetTrp: 0.231 ± 0.014	0.308MetTyr: 0.308 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.195AsnAla: 2.195 ± 0.047	0.112AsnCys: 0.112 ± 0.01	1.095AsnAsp: 1.095 ± 0.029	0.807AsnGlu: 0.807 ± 0.03	0.41AsnPhe: 0.41 ± 0.019	1.725AsnGly: 1.725 ± 0.044	0.415AsnHis: 0.415 ± 0.018	0.621AsnIle: 0.621 ± 0.023	0.421AsnLys: 0.421 ± 0.019	1.675AsnLeu: 1.675 ± 0.039	0.262AsnMet: 0.262 ± 0.017	0.407AsnAsn: 0.407 ± 0.018	1.377AsnPro: 1.377 ± 0.033	0.523AsnGln: 0.523 ± 0.023	1.122AsnArg: 1.122 ± 0.036	0.735AsnSer: 0.735 ± 0.027	0.929AsnThr: 0.929 ± 0.028	1.502AsnVal: 1.502 ± 0.04	0.218AsnTrp: 0.218 ± 0.014	0.351AsnTyr: 0.351 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	7.145ProAla: 7.145 ± 0.098	0.287ProCys: 0.287 ± 0.014	4.239ProAsp: 4.239 ± 0.065	3.559ProGlu: 3.559 ± 0.062	1.478ProPhe: 1.478 ± 0.037	5.28ProGly: 5.28 ± 0.072	1.249ProHis: 1.249 ± 0.027	1.515ProIle: 1.515 ± 0.036	1.167ProLys: 1.167 ± 0.039	4.631ProLeu: 4.631 ± 0.06	1.064ProMet: 1.064 ± 0.031	0.781ProAsn: 0.781 ± 0.027	2.598ProPro: 2.598 ± 0.05	1.854ProGln: 1.854 ± 0.043	3.526ProArg: 3.526 ± 0.059	3.396ProSer: 3.396 ± 0.058	3.67ProThr: 3.67 ± 0.07	5.156ProVal: 5.156 ± 0.073	0.935ProTrp: 0.935 ± 0.029	1.161ProTyr: 1.161 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.954GlnAla: 3.954 ± 0.065	0.172GlnCys: 0.172 ± 0.012	1.615GlnAsp: 1.615 ± 0.046	1.543GlnGlu: 1.543 ± 0.041	0.696GlnPhe: 0.696 ± 0.024	2.442GlnGly: 2.442 ± 0.055	0.908GlnHis: 0.908 ± 0.03	1.357GlnIle: 1.357 ± 0.035	0.582GlnLys: 0.582 ± 0.023	3.285GlnLeu: 3.285 ± 0.051	0.677GlnMet: 0.677 ± 0.025	0.451GlnAsn: 0.451 ± 0.019	1.917GlnPro: 1.917 ± 0.049	1.592GlnGln: 1.592 ± 0.042	2.772GlnArg: 2.772 ± 0.047	1.427GlnSer: 1.427 ± 0.036	1.637GlnThr: 1.637 ± 0.036	3.309GlnVal: 3.309 ± 0.057	0.552GlnTrp: 0.552 ± 0.021	0.552GlnTyr: 0.552 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	9.18ArgAla: 9.18 ± 0.106	0.542ArgCys: 0.542 ± 0.025	4.8ArgAsp: 4.8 ± 0.071	4.55ArgGlu: 4.55 ± 0.07	2.079ArgPhe: 2.079 ± 0.039	5.437ArgGly: 5.437 ± 0.082	1.8ArgHis: 1.8 ± 0.039	2.991ArgIle: 2.991 ± 0.056	1.516ArgLys: 1.516 ± 0.038	8.216ArgLeu: 8.216 ± 0.093	1.758ArgMet: 1.758 ± 0.039	1.218ArgAsn: 1.218 ± 0.032	4.392ArgPro: 4.392 ± 0.068	2.274ArgGln: 2.274 ± 0.048	7.51ArgArg: 7.51 ± 0.11	4.464ArgSer: 4.464 ± 0.066	5.232ArgThr: 5.232 ± 0.063	6.248ArgVal: 6.248 ± 0.083	1.472ArgTrp: 1.472 ± 0.035	1.567ArgTyr: 1.567 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.092SerAla: 7.092 ± 0.082	0.399SerCys: 0.399 ± 0.019	3.278SerAsp: 3.278 ± 0.056	2.534SerGlu: 2.534 ± 0.044	1.525SerPhe: 1.525 ± 0.039	5.699SerGly: 5.699 ± 0.088	1.126SerHis: 1.126 ± 0.029	1.873SerIle: 1.873 ± 0.045	1.198SerLys: 1.198 ± 0.038	5.081SerLeu: 5.081 ± 0.07	1.4SerMet: 1.4 ± 0.038	0.949SerAsn: 0.949 ± 0.03	3.02SerPro: 3.02 ± 0.052	1.543SerGln: 1.543 ± 0.038	3.989SerArg: 3.989 ± 0.052	3.689SerSer: 3.689 ± 0.081	4.039SerThr: 4.039 ± 0.068	4.733SerVal: 4.733 ± 0.073	1.019SerTrp: 1.019 ± 0.03	1.471SerTyr: 1.471 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	7.796ThrAla: 7.796 ± 0.089	0.482ThrCys: 0.482 ± 0.021	3.945ThrAsp: 3.945 ± 0.065	2.807ThrGlu: 2.807 ± 0.05	1.912ThrPhe: 1.912 ± 0.039	5.912ThrGly: 5.912 ± 0.079	1.288ThrHis: 1.288 ± 0.036	2.295ThrIle: 2.295 ± 0.042	1.311ThrLys: 1.311 ± 0.039	5.816ThrLeu: 5.816 ± 0.081	1.151ThrMet: 1.151 ± 0.031	1.057ThrAsn: 1.057 ± 0.03	4.116ThrPro: 4.116 ± 0.059	1.631ThrGln: 1.631 ± 0.041	4.193ThrArg: 4.193 ± 0.062	3.877ThrSer: 3.877 ± 0.075	4.544ThrThr: 4.544 ± 0.071	5.981ThrVal: 5.981 ± 0.068	1.079ThrTrp: 1.079 ± 0.033	1.473ThrTyr: 1.473 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	11.787ValAla: 11.787 ± 0.126	0.736ValCys: 0.736 ± 0.022	6.215ValAsp: 6.215 ± 0.082	5.452ValGlu: 5.452 ± 0.077	2.198ValPhe: 2.198 ± 0.049	7.6ValGly: 7.6 ± 0.091	2.071ValHis: 2.071 ± 0.043	3.586ValIle: 3.586 ± 0.064	1.777ValLys: 1.777 ± 0.042	10.007ValLeu: 10.007 ± 0.139	1.662ValMet: 1.662 ± 0.04	1.588ValAsn: 1.588 ± 0.035	4.894ValPro: 4.894 ± 0.067	2.57ValGln: 2.57 ± 0.05	7.383ValArg: 7.383 ± 0.084	4.794ValSer: 4.794 ± 0.071	6.11ValThr: 6.11 ± 0.069	10.26ValVal: 10.26 ± 0.125	1.22ValTrp: 1.22 ± 0.035	1.395ValTyr: 1.395 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.669TrpAla: 1.669 ± 0.044	0.174TrpCys: 0.174 ± 0.012	0.933TrpAsp: 0.933 ± 0.027	0.646TrpGlu: 0.646 ± 0.024	0.558TrpPhe: 0.558 ± 0.023	1.084TrpGly: 1.084 ± 0.031	0.398TrpHis: 0.398 ± 0.018	0.523TrpIle: 0.523 ± 0.024	0.339TrpLys: 0.339 ± 0.018	1.75TrpLeu: 1.75 ± 0.046	0.322TrpMet: 0.322 ± 0.017	0.334TrpAsn: 0.334 ± 0.017	0.828TrpPro: 0.828 ± 0.03	0.614TrpGln: 0.614 ± 0.023	1.3TrpArg: 1.3 ± 0.032	1.124TrpSer: 1.124 ± 0.038	1.0TrpThr: 1.0 ± 0.031	1.304TrpVal: 1.304 ± 0.036	0.428TrpTrp: 0.428 ± 0.018	0.29TrpTyr: 0.29 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.841TyrAla: 2.841 ± 0.047	0.16TyrCys: 0.16 ± 0.012	1.973TyrAsp: 1.973 ± 0.046	1.12TyrGlu: 1.12 ± 0.031	0.601TyrPhe: 0.601 ± 0.025	1.913TyrGly: 1.913 ± 0.041	0.35TyrHis: 0.35 ± 0.017	0.478TyrIle: 0.478 ± 0.02	0.389TyrLys: 0.389 ± 0.022	2.014TyrLeu: 2.014 ± 0.044	0.22TyrMet: 0.22 ± 0.012	0.408TyrAsn: 0.408 ± 0.019	0.929TyrPro: 0.929 ± 0.031	0.52TyrGln: 0.52 ± 0.025	1.45TyrArg: 1.45 ± 0.037	0.939TyrSer: 0.939 ± 0.03	1.061TyrThr: 1.061 ± 0.037	1.855TyrVal: 1.855 ± 0.041	0.299TyrTrp: 0.299 ± 0.016	0.458TyrTyr: 0.458 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3827 proteins (1160312 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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