Amino acid dipepetide frequency for Mesorhizobium carbonis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.026AlaAla: 18.026 ± 0.168	1.083AlaCys: 1.083 ± 0.026	7.248AlaAsp: 7.248 ± 0.072	7.789AlaGlu: 7.789 ± 0.091	4.866AlaPhe: 4.866 ± 0.054	11.569AlaGly: 11.569 ± 0.115	2.126AlaHis: 2.126 ± 0.043	6.946AlaIle: 6.946 ± 0.081	3.374AlaLys: 3.374 ± 0.057	13.359AlaLeu: 13.359 ± 0.153	3.831AlaMet: 3.831 ± 0.056	2.748AlaAsn: 2.748 ± 0.047	5.508AlaPro: 5.508 ± 0.074	3.506AlaGln: 3.506 ± 0.057	9.493AlaArg: 9.493 ± 0.091	6.736AlaSer: 6.736 ± 0.086	6.234AlaThr: 6.234 ± 0.075	9.039AlaVal: 9.039 ± 0.077	1.621AlaTrp: 1.621 ± 0.035	2.593AlaTyr: 2.593 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.951CysAla: 0.951 ± 0.026	0.119CysCys: 0.119 ± 0.008	0.512CysAsp: 0.512 ± 0.02	0.434CysGlu: 0.434 ± 0.017	0.324CysPhe: 0.324 ± 0.014	0.884CysGly: 0.884 ± 0.025	0.248CysHis: 0.248 ± 0.014	0.361CysIle: 0.361 ± 0.015	0.145CysLys: 0.145 ± 0.01	0.721CysLeu: 0.721 ± 0.022	0.163CysMet: 0.163 ± 0.01	0.178CysAsn: 0.178 ± 0.011	0.424CysPro: 0.424 ± 0.02	0.193CysGln: 0.193 ± 0.012	0.658CysArg: 0.658 ± 0.023	0.437CysSer: 0.437 ± 0.015	0.378CysThr: 0.378 ± 0.017	0.605CysVal: 0.605 ± 0.02	0.106CysTrp: 0.106 ± 0.009	0.159CysTyr: 0.159 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.171AspAla: 7.171 ± 0.08	0.491AspCys: 0.491 ± 0.019	3.39AspAsp: 3.39 ± 0.059	3.796AspGlu: 3.796 ± 0.055	2.275AspPhe: 2.275 ± 0.044	5.685AspGly: 5.685 ± 0.088	1.328AspHis: 1.328 ± 0.027	3.047AspIle: 3.047 ± 0.045	1.503AspLys: 1.503 ± 0.032	5.885AspLeu: 5.885 ± 0.065	1.522AspMet: 1.522 ± 0.035	1.199AspAsn: 1.199 ± 0.032	3.53AspPro: 3.53 ± 0.05	1.608AspGln: 1.608 ± 0.055	4.949AspArg: 4.949 ± 0.063	2.01AspSer: 2.01 ± 0.036	2.545AspThr: 2.545 ± 0.041	4.442AspVal: 4.442 ± 0.057	0.99AspTrp: 0.99 ± 0.027	1.438AspTyr: 1.438 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	8.012GluAla: 8.012 ± 0.085	0.334GluCys: 0.334 ± 0.014	2.82GluAsp: 2.82 ± 0.043	3.151GluGlu: 3.151 ± 0.052	1.703GluPhe: 1.703 ± 0.037	4.498GluGly: 4.498 ± 0.061	1.178GluHis: 1.178 ± 0.026	3.55GluIle: 3.55 ± 0.058	2.152GluLys: 2.152 ± 0.042	5.088GluLeu: 5.088 ± 0.062	1.55GluMet: 1.55 ± 0.031	1.599GluAsn: 1.599 ± 0.034	2.925GluPro: 2.925 ± 0.053	1.905GluGln: 1.905 ± 0.038	5.297GluArg: 5.297 ± 0.073	2.216GluSer: 2.216 ± 0.04	3.796GluThr: 3.796 ± 0.053	3.772GluVal: 3.772 ± 0.052	0.689GluTrp: 0.689 ± 0.025	0.908GluTyr: 0.908 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.785PheAla: 4.785 ± 0.064	0.38PheCys: 0.38 ± 0.019	2.764PheAsp: 2.764 ± 0.042	2.277PheGlu: 2.277 ± 0.04	1.539PhePhe: 1.539 ± 0.039	3.913PheGly: 3.913 ± 0.053	0.796PheHis: 0.796 ± 0.025	1.65PheIle: 1.65 ± 0.036	0.895PheLys: 0.895 ± 0.025	3.615PheLeu: 3.615 ± 0.062	0.868PheMet: 0.868 ± 0.024	0.991PheAsn: 0.991 ± 0.023	1.684PhePro: 1.684 ± 0.031	1.022PheGln: 1.022 ± 0.026	2.495PheArg: 2.495 ± 0.045	2.292PheSer: 2.292 ± 0.046	1.845PheThr: 1.845 ± 0.031	3.183PheVal: 3.183 ± 0.052	0.575PheTrp: 0.575 ± 0.019	0.871PheTyr: 0.871 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.745GlyAla: 9.745 ± 0.131	0.806GlyCys: 0.806 ± 0.021	4.664GlyAsp: 4.664 ± 0.071	5.054GlyGlu: 5.054 ± 0.062	3.952GlyPhe: 3.952 ± 0.053	7.941GlyGly: 7.941 ± 0.197	1.984GlyHis: 1.984 ± 0.037	4.915GlyIle: 4.915 ± 0.069	3.008GlyLys: 3.008 ± 0.051	9.071GlyLeu: 9.071 ± 0.089	2.597GlyMet: 2.597 ± 0.044	2.111GlyAsn: 2.111 ± 0.048	3.53GlyPro: 3.53 ± 0.046	2.693GlyGln: 2.693 ± 0.047	6.897GlyArg: 6.897 ± 0.07	4.852GlySer: 4.852 ± 0.088	4.683GlyThr: 4.683 ± 0.08	6.361GlyVal: 6.361 ± 0.067	1.395GlyTrp: 1.395 ± 0.036	2.299GlyTyr: 2.299 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	2.443HisAla: 2.443 ± 0.038	0.216HisCys: 0.216 ± 0.012	1.296HisAsp: 1.296 ± 0.028	1.065HisGlu: 1.065 ± 0.029	0.869HisPhe: 0.869 ± 0.026	2.104HisGly: 2.104 ± 0.04	0.598HisHis: 0.598 ± 0.023	0.831HisIle: 0.831 ± 0.025	0.416HisLys: 0.416 ± 0.016	1.992HisLeu: 1.992 ± 0.044	0.478HisMet: 0.478 ± 0.019	0.391HisAsn: 0.391 ± 0.017	1.349HisPro: 1.349 ± 0.033	0.526HisGln: 0.526 ± 0.02	1.535HisArg: 1.535 ± 0.032	0.929HisSer: 0.929 ± 0.023	0.796HisThr: 0.796 ± 0.023	1.693HisVal: 1.693 ± 0.034	0.307HisTrp: 0.307 ± 0.013	0.532HisTyr: 0.532 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.644IleAla: 7.644 ± 0.074	0.477IleCys: 0.477 ± 0.017	3.817IleAsp: 3.817 ± 0.045	3.632IleGlu: 3.632 ± 0.055	1.71IlePhe: 1.71 ± 0.041	5.293IleGly: 5.293 ± 0.092	0.987IleHis: 0.987 ± 0.023	2.27IleIle: 2.27 ± 0.041	1.13IleLys: 1.13 ± 0.03	4.596IleLeu: 4.596 ± 0.06	0.997IleMet: 0.997 ± 0.029	1.253IleAsn: 1.253 ± 0.032	2.291IlePro: 2.291 ± 0.045	1.102IleGln: 1.102 ± 0.032	3.47IleArg: 3.47 ± 0.05	2.705IleSer: 2.705 ± 0.052	2.467IleThr: 2.467 ± 0.047	4.731IleVal: 4.731 ± 0.063	0.611IleTrp: 0.611 ± 0.02	1.07IleTyr: 1.07 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.099LysAla: 4.099 ± 0.057	0.132LysCys: 0.132 ± 0.012	1.566LysAsp: 1.566 ± 0.036	1.336LysGlu: 1.336 ± 0.034	0.723LysPhe: 0.723 ± 0.021	2.431LysGly: 2.431 ± 0.042	0.533LysHis: 0.533 ± 0.019	1.435LysIle: 1.435 ± 0.031	1.052LysLys: 1.052 ± 0.033	2.819LysLeu: 2.819 ± 0.052	0.664LysMet: 0.664 ± 0.022	0.715LysAsn: 0.715 ± 0.025	1.917LysPro: 1.917 ± 0.036	0.856LysGln: 0.856 ± 0.028	2.192LysArg: 2.192 ± 0.042	1.609LysSer: 1.609 ± 0.037	1.672LysThr: 1.672 ± 0.035	2.23LysVal: 2.23 ± 0.041	0.325LysTrp: 0.325 ± 0.015	0.522LysTyr: 0.522 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	13.721LeuAla: 13.721 ± 0.137	0.835LeuCys: 0.835 ± 0.023	6.257LeuAsp: 6.257 ± 0.065	5.073LeuGlu: 5.073 ± 0.062	3.799LeuPhe: 3.799 ± 0.058	8.155LeuGly: 8.155 ± 0.078	1.838LeuHis: 1.838 ± 0.035	4.66LeuIle: 4.66 ± 0.065	3.258LeuLys: 3.258 ± 0.052	9.091LeuLeu: 9.091 ± 0.117	2.317LeuMet: 2.317 ± 0.046	2.244LeuAsn: 2.244 ± 0.033	5.377LeuPro: 5.377 ± 0.07	2.385LeuGln: 2.385 ± 0.038	6.758LeuArg: 6.758 ± 0.074	6.56LeuSer: 6.56 ± 0.109	5.242LeuThr: 5.242 ± 0.072	7.982LeuVal: 7.982 ± 0.089	1.121LeuTrp: 1.121 ± 0.03	1.936LeuTyr: 1.936 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.373MetAla: 3.373 ± 0.05	0.144MetCys: 0.144 ± 0.009	1.174MetAsp: 1.174 ± 0.026	1.206MetGlu: 1.206 ± 0.023	0.739MetPhe: 0.739 ± 0.024	1.925MetGly: 1.925 ± 0.04	0.463MetHis: 0.463 ± 0.017	1.461MetIle: 1.461 ± 0.036	0.987MetLys: 0.987 ± 0.026	2.556MetLeu: 2.556 ± 0.045	0.726MetMet: 0.726 ± 0.025	0.864MetAsn: 0.864 ± 0.024	1.578MetPro: 1.578 ± 0.03	0.83MetGln: 0.83 ± 0.023	1.97MetArg: 1.97 ± 0.035	1.676MetSer: 1.676 ± 0.031	1.92MetThr: 1.92 ± 0.037	1.835MetVal: 1.835 ± 0.038	0.218MetTrp: 0.218 ± 0.013	0.294MetTyr: 0.294 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.094AsnAla: 3.094 ± 0.05	0.217AsnCys: 0.217 ± 0.011	1.324AsnAsp: 1.324 ± 0.034	1.193AsnGlu: 1.193 ± 0.031	0.854AsnPhe: 0.854 ± 0.025	2.242AsnGly: 2.242 ± 0.051	0.486AsnHis: 0.486 ± 0.017	1.214AsnIle: 1.214 ± 0.033	0.548AsnLys: 0.548 ± 0.02	2.368AsnLeu: 2.368 ± 0.04	0.598AsnMet: 0.598 ± 0.022	0.567AsnAsn: 0.567 ± 0.019	1.739AsnPro: 1.739 ± 0.034	0.691AsnGln: 0.691 ± 0.022	1.809AsnArg: 1.809 ± 0.036	1.087AsnSer: 1.087 ± 0.033	1.124AsnThr: 1.124 ± 0.031	1.865AsnVal: 1.865 ± 0.035	0.389AsnTrp: 0.389 ± 0.015	0.615AsnTyr: 0.615 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.342ProAla: 6.342 ± 0.092	0.328ProCys: 0.328 ± 0.016	3.858ProAsp: 3.858 ± 0.054	3.487ProGlu: 3.487 ± 0.05	2.075ProPhe: 2.075 ± 0.034	4.715ProGly: 4.715 ± 0.055	1.065ProHis: 1.065 ± 0.027	2.331ProIle: 2.331 ± 0.04	1.446ProLys: 1.446 ± 0.035	4.646ProLeu: 4.646 ± 0.065	1.225ProMet: 1.225 ± 0.03	1.21ProAsn: 1.21 ± 0.028	2.412ProPro: 2.412 ± 0.052	1.508ProGln: 1.508 ± 0.032	3.185ProArg: 3.185 ± 0.047	2.775ProSer: 2.775 ± 0.046	2.412ProThr: 2.412 ± 0.039	4.372ProVal: 4.372 ± 0.059	0.693ProTrp: 0.693 ± 0.02	1.134ProTyr: 1.134 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	3.847GlnAla: 3.847 ± 0.058	0.17GlnCys: 0.17 ± 0.011	1.361GlnAsp: 1.361 ± 0.025	1.319GlnGlu: 1.319 ± 0.029	0.971GlnPhe: 0.971 ± 0.025	2.202GlnGly: 2.202 ± 0.036	0.534GlnHis: 0.534 ± 0.018	1.662GlnIle: 1.662 ± 0.075	0.936GlnLys: 0.936 ± 0.026	2.401GlnLeu: 2.401 ± 0.042	0.806GlnMet: 0.806 ± 0.021	0.765GlnAsn: 0.765 ± 0.022	1.647GlnPro: 1.647 ± 0.038	0.95GlnGln: 0.95 ± 0.03	2.234GlnArg: 2.234 ± 0.038	1.597GlnSer: 1.597 ± 0.038	1.57GlnThr: 1.57 ± 0.031	2.165GlnVal: 2.165 ± 0.07	0.352GlnTrp: 0.352 ± 0.015	0.529GlnTyr: 0.529 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	8.329ArgAla: 8.329 ± 0.096	0.498ArgCys: 0.498 ± 0.018	4.516ArgAsp: 4.516 ± 0.061	4.306ArgGlu: 4.306 ± 0.058	3.209ArgPhe: 3.209 ± 0.052	5.077ArgGly: 5.077 ± 0.065	1.907ArgHis: 1.907 ± 0.031	4.345ArgIle: 4.345 ± 0.056	2.27ArgLys: 2.27 ± 0.048	8.297ArgLeu: 8.297 ± 0.095	2.145ArgMet: 2.145 ± 0.039	1.867ArgAsn: 1.867 ± 0.04	3.828ArgPro: 3.828 ± 0.058	2.548ArgGln: 2.548 ± 0.046	6.387ArgArg: 6.387 ± 0.085	3.992ArgSer: 3.992 ± 0.056	3.724ArgThr: 3.724 ± 0.047	4.857ArgVal: 4.857 ± 0.057	1.074ArgTrp: 1.074 ± 0.027	1.71ArgTyr: 1.71 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	6.313SerAla: 6.313 ± 0.102	0.393SerCys: 0.393 ± 0.017	2.933SerAsp: 2.933 ± 0.042	2.75SerGlu: 2.75 ± 0.041	2.324SerPhe: 2.324 ± 0.04	5.611SerGly: 5.611 ± 0.074	1.065SerHis: 1.065 ± 0.028	2.948SerIle: 2.948 ± 0.049	1.376SerLys: 1.376 ± 0.029	5.285SerLeu: 5.285 ± 0.066	1.42SerMet: 1.42 ± 0.033	1.266SerAsn: 1.266 ± 0.03	2.808SerPro: 2.808 ± 0.042	1.428SerGln: 1.428 ± 0.034	3.847SerArg: 3.847 ± 0.06	2.919SerSer: 2.919 ± 0.048	2.863SerThr: 2.863 ± 0.068	4.098SerVal: 4.098 ± 0.06	0.723SerTrp: 0.723 ± 0.021	1.213SerTyr: 1.213 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	6.247ThrAla: 6.247 ± 0.087	0.4ThrCys: 0.4 ± 0.016	2.853ThrAsp: 2.853 ± 0.054	2.581ThrGlu: 2.581 ± 0.038	1.993ThrPhe: 1.993 ± 0.039	5.425ThrGly: 5.425 ± 0.071	0.988ThrHis: 0.988 ± 0.026	3.181ThrIle: 3.181 ± 0.05	1.322ThrLys: 1.322 ± 0.032	5.553ThrLeu: 5.553 ± 0.063	1.289ThrMet: 1.289 ± 0.03	1.214ThrAsn: 1.214 ± 0.037	3.073ThrPro: 3.073 ± 0.042	1.272ThrGln: 1.272 ± 0.035	3.398ThrArg: 3.398 ± 0.05	2.696ThrSer: 2.696 ± 0.047	2.854ThrThr: 2.854 ± 0.074	4.406ThrVal: 4.406 ± 0.063	0.652ThrTrp: 0.652 ± 0.018	1.101ThrTyr: 1.101 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	9.899ValAla: 9.899 ± 0.086	0.62ValCys: 0.62 ± 0.021	4.412ValAsp: 4.412 ± 0.061	4.918ValGlu: 4.918 ± 0.06	3.03ValPhe: 3.03 ± 0.051	5.911ValGly: 5.911 ± 0.087	1.481ValHis: 1.481 ± 0.035	3.956ValIle: 3.956 ± 0.057	2.031ValLys: 2.031 ± 0.043	7.484ValLeu: 7.484 ± 0.079	1.902ValMet: 1.902 ± 0.037	1.913ValAsn: 1.913 ± 0.041	3.821ValPro: 3.821 ± 0.057	1.876ValGln: 1.876 ± 0.031	5.274ValArg: 5.274 ± 0.067	4.547ValSer: 4.547 ± 0.071	4.528ValThr: 4.528 ± 0.061	6.353ValVal: 6.353 ± 0.074	0.953ValTrp: 0.953 ± 0.027	1.569ValTyr: 1.569 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.232TrpAla: 1.232 ± 0.029	0.131TrpCys: 0.131 ± 0.008	0.656TrpAsp: 0.656 ± 0.021	0.601TrpGlu: 0.601 ± 0.02	0.589TrpPhe: 0.589 ± 0.02	0.922TrpGly: 0.922 ± 0.026	0.31TrpHis: 0.31 ± 0.014	0.681TrpIle: 0.681 ± 0.022	0.456TrpLys: 0.456 ± 0.018	1.619TrpLeu: 1.619 ± 0.036	0.375TrpMet: 0.375 ± 0.016	0.446TrpAsn: 0.446 ± 0.018	0.711TrpPro: 0.711 ± 0.023	0.487TrpGln: 0.487 ± 0.016	1.212TrpArg: 1.212 ± 0.029	0.854TrpSer: 0.854 ± 0.025	0.803TrpThr: 0.803 ± 0.026	0.767TrpVal: 0.767 ± 0.019	0.219TrpTrp: 0.219 ± 0.013	0.291TrpTyr: 0.291 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.423TyrAla: 2.423 ± 0.047	0.227TyrCys: 0.227 ± 0.013	1.381TyrAsp: 1.381 ± 0.031	1.176TyrGlu: 1.176 ± 0.026	0.893TyrPhe: 0.893 ± 0.025	2.054TyrGly: 2.054 ± 0.04	0.451TyrHis: 0.451 ± 0.019	0.809TyrIle: 0.809 ± 0.022	0.523TyrLys: 0.523 ± 0.019	2.163TyrLeu: 2.163 ± 0.037	0.465TyrMet: 0.465 ± 0.019	0.481TyrAsn: 0.481 ± 0.02	1.07TyrPro: 1.07 ± 0.029	0.63TyrGln: 0.63 ± 0.022	1.827TyrArg: 1.827 ± 0.041	1.094TyrSer: 1.094 ± 0.029	1.041TyrThr: 1.041 ± 0.027	1.722TyrVal: 1.722 ± 0.036	0.351TyrTrp: 0.351 ± 0.014	0.528TyrTyr: 0.528 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4987 proteins (1586296 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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