Amino acid dipepetide frequency for Diuris virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.296AlaAla: 2.296 ± 0.117
1.914AlaCys: 1.914 ± 0.277
0.0AlaAsp: 0.0 ± 0.0
3.444AlaGlu: 3.444 ± 0.365
2.679AlaPhe: 2.679 ± 1.036
2.679AlaGly: 2.679 ± 0.044
1.148AlaHis: 1.148 ± 0.599
3.062AlaIle: 3.062 ± 1.956
3.827AlaLys: 3.827 ± 1.606
5.358AlaLeu: 5.358 ± 1.169
1.531AlaMet: 1.531 ± 0.643
3.827AlaAsn: 3.827 ± 1.606
0.765AlaPro: 0.765 ± 0.321
1.148AlaGln: 1.148 ± 0.482
2.679AlaArg: 2.679 ± 1.036
3.062AlaSer: 3.062 ± 0.876
0.765AlaThr: 0.765 ± 0.321
2.679AlaVal: 2.679 ± 1.036
0.0AlaTrp: 0.0 ± 0.0
1.148AlaTyr: 1.148 ± 0.482
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.531CysCys: 1.531 ± 0.643
0.383CysAsp: 0.383 ± 0.161
1.148CysGlu: 1.148 ± 0.599
2.296CysPhe: 2.296 ± 0.117
0.765CysGly: 0.765 ± 0.321
0.383CysHis: 0.383 ± 0.161
1.914CysIle: 1.914 ± 0.277
1.914CysLys: 1.914 ± 0.277
2.679CysLeu: 2.679 ± 0.044
0.383CysMet: 0.383 ± 0.334
0.765CysAsn: 0.765 ± 0.321
0.0CysPro: 0.0 ± 0.0
0.765CysGln: 0.765 ± 0.321
1.148CysArg: 1.148 ± 0.599
2.296CysSer: 2.296 ± 0.964
1.148CysThr: 1.148 ± 0.599
1.148CysVal: 1.148 ± 0.599
0.383CysTrp: 0.383 ± 0.161
0.765CysTyr: 0.765 ± 0.759
0.0CysXaa: 0.0 ± 0.0
Asp
2.679AspAla: 2.679 ± 1.036
3.062AspCys: 3.062 ± 0.205
3.062AspAsp: 3.062 ± 0.205
7.654AspGlu: 7.654 ± 1.109
3.444AspPhe: 3.444 ± 1.446
3.444AspGly: 3.444 ± 0.715
1.148AspHis: 1.148 ± 0.482
2.679AspIle: 2.679 ± 3.197
3.062AspLys: 3.062 ± 0.205
2.679AspLeu: 2.679 ± 1.125
0.383AspMet: 0.383 ± 0.161
4.21AspAsn: 4.21 ± 1.474
1.531AspPro: 1.531 ± 1.518
1.531AspGln: 1.531 ± 0.643
1.531AspArg: 1.531 ± 1.518
3.062AspSer: 3.062 ± 1.285
1.148AspThr: 1.148 ± 0.482
3.062AspVal: 3.062 ± 1.285
1.531AspTrp: 1.531 ± 0.643
2.296AspTyr: 2.296 ± 0.117
0.0AspXaa: 0.0 ± 0.0
Glu
3.827GluAla: 3.827 ± 1.635
1.914GluCys: 1.914 ± 0.277
4.592GluAsp: 4.592 ± 0.233
7.271GluGlu: 7.271 ± 4.511
2.679GluPhe: 2.679 ± 0.044
2.296GluGly: 2.296 ± 0.117
0.383GluHis: 0.383 ± 0.92
7.654GluIle: 7.654 ± 1.052
8.037GluLys: 8.037 ± 0.132
4.975GluLeu: 4.975 ± 1.008
3.444GluMet: 3.444 ± 0.715
3.827GluAsn: 3.827 ± 0.526
1.531GluPro: 1.531 ± 0.643
2.679GluGln: 2.679 ± 1.125
6.506GluArg: 6.506 ± 3.752
7.654GluSer: 7.654 ± 1.109
2.679GluThr: 2.679 ± 0.044
4.975GluVal: 4.975 ± 2.234
0.765GluTrp: 0.765 ± 0.321
4.592GluTyr: 4.592 ± 1.928
0.0GluXaa: 0.0 ± 0.0
Phe
3.062PheAla: 3.062 ± 0.205
0.383PheCys: 0.383 ± 0.161
5.358PheAsp: 5.358 ± 2.073
4.592PheGlu: 4.592 ± 0.233
3.444PhePhe: 3.444 ± 0.365
2.296PheGly: 2.296 ± 0.117
0.383PheHis: 0.383 ± 0.161
2.679PheIle: 2.679 ± 2.117
4.21PheLys: 4.21 ± 1.767
5.358PheLeu: 5.358 ± 2.249
1.914PheMet: 1.914 ± 0.803
2.679PheAsn: 2.679 ± 0.044
1.148PhePro: 1.148 ± 0.482
1.914PheGln: 1.914 ± 0.277
3.444PheArg: 3.444 ± 1.796
4.592PheSer: 4.592 ± 1.928
1.148PheThr: 1.148 ± 0.482
0.765PheVal: 0.765 ± 0.759
1.148PheTrp: 1.148 ± 0.482
1.914PheTyr: 1.914 ± 0.803
0.0PheXaa: 0.0 ± 0.0
Gly
1.148GlyAla: 1.148 ± 1.679
1.531GlyCys: 1.531 ± 0.438
1.914GlyAsp: 1.914 ± 0.803
5.358GlyGlu: 5.358 ± 0.992
3.062GlyPhe: 3.062 ± 0.876
3.444GlyGly: 3.444 ± 6.118
1.148GlyHis: 1.148 ± 0.482
1.914GlyIle: 1.914 ± 1.358
3.444GlyLys: 3.444 ± 0.365
5.358GlyLeu: 5.358 ± 2.249
0.383GlyMet: 0.383 ± 0.161
2.296GlyAsn: 2.296 ± 0.964
2.296GlyPro: 2.296 ± 1.197
1.148GlyGln: 1.148 ± 0.482
4.592GlyArg: 4.592 ± 4.555
4.975GlySer: 4.975 ± 4.395
1.914GlyThr: 1.914 ± 0.803
4.975GlyVal: 4.975 ± 1.153
1.531GlyTrp: 1.531 ± 0.643
1.914GlyTyr: 1.914 ± 0.277
0.0GlyXaa: 0.0 ± 0.0
His
0.383HisAla: 0.383 ± 0.161
0.765HisCys: 0.765 ± 0.759
1.531HisAsp: 1.531 ± 0.438
0.0HisGlu: 0.0 ± 0.0
1.914HisPhe: 1.914 ± 0.277
1.148HisGly: 1.148 ± 1.679
0.383HisHis: 0.383 ± 0.161
0.765HisIle: 0.765 ± 0.321
1.148HisLys: 1.148 ± 0.599
3.062HisLeu: 3.062 ± 1.285
0.383HisMet: 0.383 ± 0.161
0.383HisAsn: 0.383 ± 0.161
1.148HisPro: 1.148 ± 0.599
0.765HisGln: 0.765 ± 0.321
1.148HisArg: 1.148 ± 0.599
1.531HisSer: 1.531 ± 0.643
0.383HisThr: 0.383 ± 0.161
1.531HisVal: 1.531 ± 0.643
0.383HisTrp: 0.383 ± 0.161
1.148HisTyr: 1.148 ± 0.482
0.0HisXaa: 0.0 ± 0.0
Ile
3.827IleAla: 3.827 ± 1.606
1.531IleCys: 1.531 ± 0.643
3.827IleAsp: 3.827 ± 2.716
4.21IleGlu: 4.21 ± 0.394
3.444IlePhe: 3.444 ± 0.365
3.827IleGly: 3.827 ± 1.635
3.062IleHis: 3.062 ± 0.876
7.271IleIle: 7.271 ± 3.431
8.037IleLys: 8.037 ± 0.948
3.827IleLeu: 3.827 ± 1.606
2.296IleMet: 2.296 ± 0.117
3.827IleAsn: 3.827 ± 0.526
1.531IlePro: 1.531 ± 1.518
2.296IleGln: 2.296 ± 0.117
2.679IleArg: 2.679 ± 0.044
6.123IleSer: 6.123 ± 2.832
3.062IleThr: 3.062 ± 0.205
2.296IleVal: 2.296 ± 0.964
0.383IleTrp: 0.383 ± 0.161
4.21IleTyr: 4.21 ± 0.394
0.0IleXaa: 0.0 ± 0.0
Lys
3.444LysAla: 3.444 ± 0.715
0.765LysCys: 0.765 ± 0.321
3.827LysAsp: 3.827 ± 1.606
5.741LysGlu: 5.741 ± 2.41
2.679LysPhe: 2.679 ± 1.036
5.741LysGly: 5.741 ± 0.832
1.914LysHis: 1.914 ± 0.803
5.741LysIle: 5.741 ± 2.41
9.185LysLys: 9.185 ± 1.695
6.506LysLeu: 6.506 ± 1.591
2.296LysMet: 2.296 ± 0.964
4.592LysAsn: 4.592 ± 0.847
1.914LysPro: 1.914 ± 0.277
1.531LysGln: 1.531 ± 0.643
4.975LysArg: 4.975 ± 1.153
4.21LysSer: 4.21 ± 0.687
5.358LysThr: 5.358 ± 1.169
4.975LysVal: 4.975 ± 1.153
0.0LysTrp: 0.0 ± 0.0
3.444LysTyr: 3.444 ± 0.365
0.0LysXaa: 0.0 ± 0.0
Leu
4.21LeuAla: 4.21 ± 1.767
1.148LeuCys: 1.148 ± 0.599
6.123LeuAsp: 6.123 ± 0.671
3.827LeuGlu: 3.827 ± 1.606
1.531LeuPhe: 1.531 ± 0.643
6.506LeuGly: 6.506 ± 0.57
0.765LeuHis: 0.765 ± 0.321
5.741LeuIle: 5.741 ± 1.329
7.654LeuLys: 7.654 ± 3.213
11.864LeuLeu: 11.864 ± 2.819
3.062LeuMet: 3.062 ± 1.285
6.889LeuAsn: 6.889 ± 2.892
3.062LeuPro: 3.062 ± 1.285
1.914LeuGln: 1.914 ± 0.277
5.358LeuArg: 5.358 ± 1.169
9.568LeuSer: 9.568 ± 2.936
5.358LeuThr: 5.358 ± 2.249
5.358LeuVal: 5.358 ± 0.088
0.383LeuTrp: 0.383 ± 0.92
1.914LeuTyr: 1.914 ± 0.803
0.0LeuXaa: 0.0 ± 0.0
Met
1.148MetAla: 1.148 ± 0.482
0.765MetCys: 0.765 ± 0.759
1.148MetAsp: 1.148 ± 0.482
1.914MetGlu: 1.914 ± 0.803
0.383MetPhe: 0.383 ± 0.161
1.531MetGly: 1.531 ± 0.438
0.383MetHis: 0.383 ± 0.161
1.531MetIle: 1.531 ± 0.643
1.914MetLys: 1.914 ± 0.803
3.062MetLeu: 3.062 ± 1.285
1.531MetMet: 1.531 ± 0.643
1.914MetAsn: 1.914 ± 0.803
0.765MetPro: 0.765 ± 0.759
1.148MetGln: 1.148 ± 0.599
2.679MetArg: 2.679 ± 1.125
2.679MetSer: 2.679 ± 1.036
0.765MetThr: 0.765 ± 0.321
0.765MetVal: 0.765 ± 0.321
0.383MetTrp: 0.383 ± 0.161
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.296AsnAla: 2.296 ± 0.117
0.765AsnCys: 0.765 ± 0.759
2.296AsnAsp: 2.296 ± 0.964
4.21AsnGlu: 4.21 ± 0.687
3.444AsnPhe: 3.444 ± 0.365
2.679AsnGly: 2.679 ± 1.036
0.765AsnHis: 0.765 ± 0.321
4.975AsnIle: 4.975 ± 0.073
4.975AsnLys: 4.975 ± 0.073
4.592AsnLeu: 4.592 ± 0.847
1.914AsnMet: 1.914 ± 0.803
2.296AsnAsn: 2.296 ± 0.964
1.148AsnPro: 1.148 ± 0.482
1.531AsnGln: 1.531 ± 0.643
3.444AsnArg: 3.444 ± 1.446
1.914AsnSer: 1.914 ± 0.803
1.914AsnThr: 1.914 ± 0.803
3.062AsnVal: 3.062 ± 1.956
0.765AsnTrp: 0.765 ± 0.321
2.679AsnTyr: 2.679 ± 0.044
0.0AsnXaa: 0.0 ± 0.0
Pro
3.062ProAla: 3.062 ± 0.205
0.0ProCys: 0.0 ± 0.0
3.062ProAsp: 3.062 ± 1.285
1.531ProGlu: 1.531 ± 0.438
2.296ProPhe: 2.296 ± 0.117
2.679ProGly: 2.679 ± 1.036
0.0ProHis: 0.0 ± 0.0
1.531ProIle: 1.531 ± 0.438
1.914ProLys: 1.914 ± 0.277
0.765ProLeu: 0.765 ± 0.321
0.383ProMet: 0.383 ± 0.161
1.148ProAsn: 1.148 ± 1.679
0.765ProPro: 0.765 ± 0.321
0.383ProGln: 0.383 ± 0.161
1.148ProArg: 1.148 ± 0.599
2.296ProSer: 2.296 ± 1.197
2.296ProThr: 2.296 ± 0.964
2.679ProVal: 2.679 ± 1.125
0.765ProTrp: 0.765 ± 0.759
1.148ProTyr: 1.148 ± 0.482
0.0ProXaa: 0.0 ± 0.0
Gln
1.148GlnAla: 1.148 ± 0.482
0.383GlnCys: 0.383 ± 0.161
0.383GlnAsp: 0.383 ± 0.161
2.296GlnGlu: 2.296 ± 0.117
1.531GlnPhe: 1.531 ± 0.643
1.914GlnGly: 1.914 ± 0.277
0.383GlnHis: 0.383 ± 0.161
0.765GlnIle: 0.765 ± 0.321
2.296GlnLys: 2.296 ± 0.117
2.679GlnLeu: 2.679 ± 1.125
1.148GlnMet: 1.148 ± 0.482
1.148GlnAsn: 1.148 ± 0.482
1.531GlnPro: 1.531 ± 0.643
0.383GlnGln: 0.383 ± 0.161
1.914GlnArg: 1.914 ± 0.277
3.444GlnSer: 3.444 ± 0.365
0.765GlnThr: 0.765 ± 0.321
1.914GlnVal: 1.914 ± 0.277
0.0GlnTrp: 0.0 ± 0.0
0.383GlnTyr: 0.383 ± 0.161
0.0GlnXaa: 0.0 ± 0.0
Arg
1.914ArgAla: 1.914 ± 1.358
1.914ArgCys: 1.914 ± 0.277
2.296ArgAsp: 2.296 ± 2.278
6.889ArgGlu: 6.889 ± 3.591
5.741ArgPhe: 5.741 ± 2.41
3.062ArgGly: 3.062 ± 3.037
1.531ArgHis: 1.531 ± 0.643
1.531ArgIle: 1.531 ± 1.518
3.444ArgLys: 3.444 ± 1.796
7.654ArgLeu: 7.654 ± 3.213
1.531ArgMet: 1.531 ± 1.518
1.914ArgAsn: 1.914 ± 1.358
0.765ArgPro: 0.765 ± 0.321
1.148ArgGln: 1.148 ± 0.482
4.592ArgArg: 4.592 ± 0.233
7.654ArgSer: 7.654 ± 4.351
3.062ArgThr: 3.062 ± 0.205
3.827ArgVal: 3.827 ± 1.635
0.0ArgTrp: 0.0 ± 0.0
2.296ArgTyr: 2.296 ± 0.964
0.0ArgXaa: 0.0 ± 0.0
Ser
2.679SerAla: 2.679 ± 0.044
2.296SerCys: 2.296 ± 0.117
4.592SerAsp: 4.592 ± 0.233
7.654SerGlu: 7.654 ± 3.27
3.827SerPhe: 3.827 ± 0.555
4.21SerGly: 4.21 ± 0.394
3.062SerHis: 3.062 ± 0.205
9.568SerIle: 9.568 ± 3.547
4.975SerLys: 4.975 ± 0.073
7.654SerLeu: 7.654 ± 1.052
1.148SerMet: 1.148 ± 0.429
3.444SerAsn: 3.444 ± 0.715
3.827SerPro: 3.827 ± 1.606
2.679SerGln: 2.679 ± 1.125
4.975SerArg: 4.975 ± 0.073
8.419SerSer: 8.419 ± 0.788
1.914SerThr: 1.914 ± 0.277
3.444SerVal: 3.444 ± 1.796
1.148SerTrp: 1.148 ± 0.482
6.123SerTyr: 6.123 ± 1.49
0.0SerXaa: 0.0 ± 0.0
Thr
1.531ThrAla: 1.531 ± 0.643
0.0ThrCys: 0.0 ± 0.0
0.765ThrAsp: 0.765 ± 0.321
4.592ThrGlu: 4.592 ± 1.314
3.444ThrPhe: 3.444 ± 1.446
3.062ThrGly: 3.062 ± 0.205
0.383ThrHis: 0.383 ± 0.161
3.444ThrIle: 3.444 ± 0.365
2.679ThrLys: 2.679 ± 0.044
3.827ThrLeu: 3.827 ± 1.606
1.531ThrMet: 1.531 ± 0.643
0.383ThrAsn: 0.383 ± 0.161
1.914ThrPro: 1.914 ± 0.803
1.531ThrGln: 1.531 ± 0.643
1.914ThrArg: 1.914 ± 0.803
2.296ThrSer: 2.296 ± 0.964
0.765ThrThr: 0.765 ± 0.321
1.914ThrVal: 1.914 ± 0.803
0.383ThrTrp: 0.383 ± 0.161
0.765ThrTyr: 0.765 ± 0.321
0.0ThrXaa: 0.0 ± 0.0
Val
3.062ValAla: 3.062 ± 0.205
0.765ValCys: 0.765 ± 0.321
5.358ValAsp: 5.358 ± 0.992
4.975ValGlu: 4.975 ± 1.008
3.062ValPhe: 3.062 ± 1.956
1.148ValGly: 1.148 ± 0.599
1.531ValHis: 1.531 ± 1.518
3.062ValIle: 3.062 ± 0.205
3.444ValLys: 3.444 ± 0.365
4.21ValLeu: 4.21 ± 1.474
0.765ValMet: 0.765 ± 0.321
3.062ValAsn: 3.062 ± 0.876
2.679ValPro: 2.679 ± 2.117
0.765ValGln: 0.765 ± 0.759
4.21ValArg: 4.21 ± 0.394
7.271ValSer: 7.271 ± 1.972
2.296ValThr: 2.296 ± 0.964
3.062ValVal: 3.062 ± 0.205
0.0ValTrp: 0.0 ± 0.0
1.148ValTyr: 1.148 ± 0.599
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.383TrpAsp: 0.383 ± 0.161
1.148TrpGlu: 1.148 ± 0.482
0.765TrpPhe: 0.765 ± 0.321
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.148TrpIle: 1.148 ± 0.482
0.765TrpLys: 0.765 ± 0.321
1.914TrpLeu: 1.914 ± 0.803
0.0TrpMet: 0.0 ± 0.0
0.383TrpAsn: 0.383 ± 0.161
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.914TrpArg: 1.914 ± 1.358
0.383TrpSer: 0.383 ± 0.161
0.0TrpThr: 0.0 ± 0.0
1.531TrpVal: 1.531 ± 0.643
0.383TrpTrp: 0.383 ± 0.161
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.296TyrAla: 2.296 ± 0.964
0.765TyrCys: 0.765 ± 0.321
2.296TyrAsp: 2.296 ± 0.964
3.827TyrGlu: 3.827 ± 0.526
0.765TyrPhe: 0.765 ± 0.321
1.914TyrGly: 1.914 ± 0.803
1.148TyrHis: 1.148 ± 0.599
4.592TyrIle: 4.592 ± 1.928
1.914TyrLys: 1.914 ± 0.803
4.21TyrLeu: 4.21 ± 1.767
0.0TyrMet: 0.0 ± 0.0
2.679TyrAsn: 2.679 ± 1.125
1.531TyrPro: 1.531 ± 0.438
1.148TyrGln: 1.148 ± 0.599
1.914TyrArg: 1.914 ± 1.358
4.21TyrSer: 4.21 ± 1.474
0.383TyrThr: 0.383 ± 0.161
1.914TyrVal: 1.914 ± 0.803
0.383TyrTrp: 0.383 ± 0.161
3.062TyrTyr: 3.062 ± 0.205
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2614 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski