Amino acid dipepetide frequency for Chilli leaf curl India virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.394AlaAla: 7.394 ± 1.879
0.924AlaCys: 0.924 ± 0.756
0.924AlaAsp: 0.924 ± 0.756
2.773AlaGlu: 2.773 ± 1.433
0.924AlaPhe: 0.924 ± 0.983
1.848AlaGly: 1.848 ± 0.762
1.848AlaHis: 1.848 ± 1.029
4.621AlaIle: 4.621 ± 2.22
2.773AlaLys: 2.773 ± 1.339
6.47AlaLeu: 6.47 ± 2.212
0.0AlaMet: 0.0 ± 0.0
1.848AlaAsn: 1.848 ± 0.762
2.773AlaPro: 2.773 ± 1.625
2.773AlaGln: 2.773 ± 1.294
5.545AlaArg: 5.545 ± 2.035
5.545AlaSer: 5.545 ± 2.729
4.621AlaThr: 4.621 ± 2.009
1.848AlaVal: 1.848 ± 1.438
1.848AlaTrp: 1.848 ± 0.762
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.848CysCys: 1.848 ± 2.111
0.0CysAsp: 0.0 ± 0.0
1.848CysGlu: 1.848 ± 1.181
0.924CysPhe: 0.924 ± 0.983
1.848CysGly: 1.848 ± 0.944
0.924CysHis: 0.924 ± 0.934
0.924CysIle: 0.924 ± 1.264
0.924CysLys: 0.924 ± 0.756
0.0CysLeu: 0.0 ± 0.0
1.848CysMet: 1.848 ± 1.064
0.924CysAsn: 0.924 ± 0.664
3.697CysPro: 3.697 ± 2.058
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.773CysSer: 2.773 ± 2.003
0.924CysThr: 0.924 ± 0.756
1.848CysVal: 1.848 ± 1.512
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.848AspAla: 1.848 ± 1.329
0.924AspCys: 0.924 ± 0.934
2.773AspAsp: 2.773 ± 1.508
2.773AspGlu: 2.773 ± 0.903
1.848AspPhe: 1.848 ± 0.762
2.773AspGly: 2.773 ± 1.993
0.924AspHis: 0.924 ± 0.983
3.697AspIle: 3.697 ± 1.699
1.848AspLys: 1.848 ± 0.762
5.545AspLeu: 5.545 ± 2.736
0.0AspMet: 0.0 ± 0.0
2.773AspAsn: 2.773 ± 1.331
1.848AspPro: 1.848 ± 1.029
0.924AspGln: 0.924 ± 0.664
2.773AspArg: 2.773 ± 1.365
4.621AspSer: 4.621 ± 1.335
0.924AspThr: 0.924 ± 1.056
5.545AspVal: 5.545 ± 1.646
2.773AspTrp: 2.773 ± 1.339
0.924AspTyr: 0.924 ± 0.664
0.0AspXaa: 0.0 ± 0.0
Glu
4.621GluAla: 4.621 ± 1.607
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
5.545GluGlu: 5.545 ± 1.84
2.773GluPhe: 2.773 ± 1.373
3.697GluGly: 3.697 ± 1.861
0.924GluHis: 0.924 ± 0.983
0.0GluIle: 0.0 ± 0.0
3.697GluLys: 3.697 ± 2.657
1.848GluLeu: 1.848 ± 1.029
0.0GluMet: 0.0 ± 0.0
5.545GluAsn: 5.545 ± 1.932
4.621GluPro: 4.621 ± 1.939
5.545GluGln: 5.545 ± 1.319
0.0GluArg: 0.0 ± 0.0
1.848GluSer: 1.848 ± 1.108
1.848GluThr: 1.848 ± 1.722
3.697GluVal: 3.697 ± 1.058
1.848GluTrp: 1.848 ± 0.944
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.924PheCys: 0.924 ± 0.756
3.697PheAsp: 3.697 ± 1.525
0.924PheGlu: 0.924 ± 0.756
0.924PhePhe: 0.924 ± 0.756
0.924PheGly: 0.924 ± 0.756
2.773PheHis: 2.773 ± 1.101
4.621PheIle: 4.621 ± 1.7
3.697PheLys: 3.697 ± 2.067
7.394PheLeu: 7.394 ± 2.277
0.924PheMet: 0.924 ± 0.664
2.773PheAsn: 2.773 ± 1.955
0.924PhePro: 0.924 ± 1.056
4.621PheGln: 4.621 ± 2.499
3.697PheArg: 3.697 ± 1.6
0.0PheSer: 0.0 ± 0.0
1.848PheThr: 1.848 ± 0.944
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.924PheTyr: 0.924 ± 0.756
0.0PheXaa: 0.0 ± 0.0
Gly
1.848GlyAla: 1.848 ± 1.329
1.848GlyCys: 1.848 ± 1.108
2.773GlyAsp: 2.773 ± 1.339
1.848GlyGlu: 1.848 ± 1.181
1.848GlyPhe: 1.848 ± 1.3
3.697GlyGly: 3.697 ± 1.134
0.924GlyHis: 0.924 ± 0.664
2.773GlyIle: 2.773 ± 0.95
7.394GlyLys: 7.394 ± 2.53
2.773GlyLeu: 2.773 ± 1.625
0.924GlyMet: 0.924 ± 1.056
0.0GlyAsn: 0.0 ± 0.0
4.621GlyPro: 4.621 ± 2.43
2.773GlyGln: 2.773 ± 1.214
1.848GlyArg: 1.848 ± 1.034
2.773GlySer: 2.773 ± 1.339
2.773GlyThr: 2.773 ± 1.101
3.697GlyVal: 3.697 ± 2.401
0.0GlyTrp: 0.0 ± 0.0
0.924GlyTyr: 0.924 ± 1.056
0.0GlyXaa: 0.0 ± 0.0
His
3.697HisAla: 3.697 ± 1.379
1.848HisCys: 1.848 ± 1.3
0.924HisAsp: 0.924 ± 0.756
0.924HisGlu: 0.924 ± 1.056
2.773HisPhe: 2.773 ± 1.373
0.924HisGly: 0.924 ± 1.056
3.697HisHis: 3.697 ± 2.626
2.773HisIle: 2.773 ± 0.903
2.773HisLys: 2.773 ± 1.59
0.924HisLeu: 0.924 ± 0.664
0.0HisMet: 0.0 ± 0.0
5.545HisAsn: 5.545 ± 2.276
1.848HisPro: 1.848 ± 1.329
2.773HisGln: 2.773 ± 1.572
3.697HisArg: 3.697 ± 2.216
0.924HisSer: 0.924 ± 0.934
1.848HisThr: 1.848 ± 1.512
1.848HisVal: 1.848 ± 1.966
0.0HisTrp: 0.0 ± 0.0
1.848HisTyr: 1.848 ± 0.944
0.0HisXaa: 0.0 ± 0.0
Ile
0.924IleAla: 0.924 ± 0.983
0.924IleCys: 0.924 ± 1.056
2.773IleAsp: 2.773 ± 1.339
2.773IleGlu: 2.773 ± 1.993
3.697IlePhe: 3.697 ± 2.657
1.848IleGly: 1.848 ± 1.512
3.697IleHis: 3.697 ± 1.497
3.697IleIle: 3.697 ± 1.37
4.621IleLys: 4.621 ± 1.777
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.0
0.924IleAsn: 0.924 ± 0.983
2.773IlePro: 2.773 ± 1.339
1.848IleGln: 1.848 ± 0.762
6.47IleArg: 6.47 ± 1.624
5.545IleSer: 5.545 ± 3.792
4.621IleThr: 4.621 ± 2.778
1.848IleVal: 1.848 ± 0.762
1.848IleTrp: 1.848 ± 1.109
1.848IleTyr: 1.848 ± 0.762
0.0IleXaa: 0.0 ± 0.0
Lys
3.697LysAla: 3.697 ± 1.103
1.848LysCys: 1.848 ± 1.034
2.773LysAsp: 2.773 ± 1.433
3.697LysGlu: 3.697 ± 1.802
1.848LysPhe: 1.848 ± 1.109
3.697LysGly: 3.697 ± 1.272
1.848LysHis: 1.848 ± 1.329
3.697LysIle: 3.697 ± 1.37
0.924LysLys: 0.924 ± 0.756
1.848LysLeu: 1.848 ± 1.329
0.924LysMet: 0.924 ± 0.756
4.621LysAsn: 4.621 ± 1.915
3.697LysPro: 3.697 ± 1.379
0.0LysGln: 0.0 ± 0.0
3.697LysArg: 3.697 ± 2.216
7.394LysSer: 7.394 ± 1.957
3.697LysThr: 3.697 ± 1.206
4.621LysVal: 4.621 ± 2.439
0.924LysTrp: 0.924 ± 0.756
4.621LysTyr: 4.621 ± 1.02
0.0LysXaa: 0.0 ± 0.0
Leu
1.848LeuAla: 1.848 ± 1.029
2.773LeuCys: 2.773 ± 1.572
4.621LeuAsp: 4.621 ± 1.848
3.697LeuGlu: 3.697 ± 1.686
0.924LeuPhe: 0.924 ± 0.664
5.545LeuGly: 5.545 ± 1.779
1.848LeuHis: 1.848 ± 1.034
3.697LeuIle: 3.697 ± 2.358
4.621LeuLys: 4.621 ± 1.624
1.848LeuLeu: 1.848 ± 1.262
3.697LeuMet: 3.697 ± 1.638
2.773LeuAsn: 2.773 ± 0.903
1.848LeuPro: 1.848 ± 0.944
0.924LeuGln: 0.924 ± 1.264
6.47LeuArg: 6.47 ± 2.282
1.848LeuSer: 1.848 ± 1.329
3.697LeuThr: 3.697 ± 1.335
3.697LeuVal: 3.697 ± 2.363
0.924LeuTrp: 0.924 ± 0.983
3.697LeuTyr: 3.697 ± 1.776
0.0LeuXaa: 0.0 ± 0.0
Met
0.924MetAla: 0.924 ± 0.756
0.924MetCys: 0.924 ± 0.756
2.773MetAsp: 2.773 ± 1.376
0.0MetGlu: 0.0 ± 0.0
2.773MetPhe: 2.773 ± 1.651
3.697MetGly: 3.697 ± 1.686
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
3.697MetLeu: 3.697 ± 1.377
1.848MetMet: 1.848 ± 1.567
1.848MetAsn: 1.848 ± 1.109
1.848MetPro: 1.848 ± 1.262
0.924MetGln: 0.924 ± 0.934
0.0MetArg: 0.0 ± 0.0
2.773MetSer: 2.773 ± 2.476
0.924MetThr: 0.924 ± 0.983
0.0MetVal: 0.0 ± 0.0
1.848MetTrp: 1.848 ± 1.029
0.924MetTyr: 0.924 ± 0.756
0.0MetXaa: 0.0 ± 0.0
Asn
2.773AsnAla: 2.773 ± 1.214
0.924AsnCys: 0.924 ± 0.934
1.848AsnAsp: 1.848 ± 1.329
1.848AsnGlu: 1.848 ± 1.181
1.848AsnPhe: 1.848 ± 0.762
0.924AsnGly: 0.924 ± 0.983
3.697AsnHis: 3.697 ± 1.777
1.848AsnIle: 1.848 ± 0.762
0.924AsnLys: 0.924 ± 0.983
5.545AsnLeu: 5.545 ± 2.848
1.848AsnMet: 1.848 ± 1.436
1.848AsnAsn: 1.848 ± 1.109
4.621AsnPro: 4.621 ± 1.107
1.848AsnGln: 1.848 ± 0.762
5.545AsnArg: 5.545 ± 2.397
5.545AsnSer: 5.545 ± 3.454
2.773AsnThr: 2.773 ± 1.373
5.545AsnVal: 5.545 ± 2.113
0.0AsnTrp: 0.0 ± 0.0
2.773AsnTyr: 2.773 ± 0.953
0.0AsnXaa: 0.0 ± 0.0
Pro
3.697ProAla: 3.697 ± 1.478
1.848ProCys: 1.848 ± 1.181
3.697ProAsp: 3.697 ± 1.85
2.773ProGlu: 2.773 ± 1.101
1.848ProPhe: 1.848 ± 1.034
0.924ProGly: 0.924 ± 0.664
2.773ProHis: 2.773 ± 1.373
5.545ProIle: 5.545 ± 1.319
6.47ProLys: 6.47 ± 2.79
3.697ProLeu: 3.697 ± 1.47
1.848ProMet: 1.848 ± 2.294
6.47ProAsn: 6.47 ± 2.56
3.697ProPro: 3.697 ± 1.47
2.773ProGln: 2.773 ± 1.905
4.621ProArg: 4.621 ± 1.834
6.47ProSer: 6.47 ± 2.763
2.773ProThr: 2.773 ± 1.433
5.545ProVal: 5.545 ± 1.806
0.0ProTrp: 0.0 ± 0.0
0.924ProTyr: 0.924 ± 0.756
0.0ProXaa: 0.0 ± 0.0
Gln
3.697GlnAla: 3.697 ± 1.512
0.0GlnCys: 0.0 ± 0.0
3.697GlnAsp: 3.697 ± 0.92
1.848GlnGlu: 1.848 ± 0.762
5.545GlnPhe: 5.545 ± 3.21
2.773GlnGly: 2.773 ± 1.373
1.848GlnHis: 1.848 ± 1.108
0.924GlnIle: 0.924 ± 0.664
0.924GlnLys: 0.924 ± 1.056
0.924GlnLeu: 0.924 ± 1.264
1.848GlnMet: 1.848 ± 0.944
0.0GlnAsn: 0.0 ± 0.0
5.545GlnPro: 5.545 ± 3.273
3.697GlnGln: 3.697 ± 1.335
2.773GlnArg: 2.773 ± 1.508
4.621GlnSer: 4.621 ± 1.107
1.848GlnThr: 1.848 ± 1.262
6.47GlnVal: 6.47 ± 1.905
0.0GlnTrp: 0.0 ± 0.0
1.848GlnTyr: 1.848 ± 0.762
0.0GlnXaa: 0.0 ± 0.0
Arg
7.394ArgAla: 7.394 ± 2.441
1.848ArgCys: 1.848 ± 2.111
3.697ArgAsp: 3.697 ± 1.379
2.773ArgGlu: 2.773 ± 1.508
1.848ArgPhe: 1.848 ± 1.109
3.697ArgGly: 3.697 ± 1.372
3.697ArgHis: 3.697 ± 0.92
2.773ArgIle: 2.773 ± 0.95
3.697ArgLys: 3.697 ± 1.721
2.773ArgLeu: 2.773 ± 2.109
0.0ArgMet: 0.0 ± 0.0
1.848ArgAsn: 1.848 ± 1.029
7.394ArgPro: 7.394 ± 1.457
1.848ArgGln: 1.848 ± 1.722
5.545ArgArg: 5.545 ± 2.855
4.621ArgSer: 4.621 ± 1.758
2.773ArgThr: 2.773 ± 1.305
7.394ArgVal: 7.394 ± 2.819
0.0ArgTrp: 0.0 ± 0.0
1.848ArgTyr: 1.848 ± 1.181
0.0ArgXaa: 0.0 ± 0.0
Ser
2.773SerAla: 2.773 ± 1.993
1.848SerCys: 1.848 ± 1.329
3.697SerAsp: 3.697 ± 1.134
3.697SerGlu: 3.697 ± 2.358
3.697SerPhe: 3.697 ± 1.335
0.924SerGly: 0.924 ± 0.664
0.924SerHis: 0.924 ± 0.934
2.773SerIle: 2.773 ± 1.905
5.545SerLys: 5.545 ± 2.855
3.697SerLeu: 3.697 ± 1.652
3.697SerMet: 3.697 ± 4.031
4.621SerAsn: 4.621 ± 1.483
8.318SerPro: 8.318 ± 3.468
3.697SerGln: 3.697 ± 1.403
7.394SerArg: 7.394 ± 2.297
9.242SerSer: 9.242 ± 3.984
4.621SerThr: 4.621 ± 2.387
4.621SerVal: 4.621 ± 2.305
0.924SerTrp: 0.924 ± 0.664
3.697SerTyr: 3.697 ± 1.403
0.0SerXaa: 0.0 ± 0.0
Thr
3.697ThrAla: 3.697 ± 1.011
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
2.773ThrGlu: 2.773 ± 1.955
0.924ThrPhe: 0.924 ± 0.664
3.697ThrGly: 3.697 ± 1.058
4.621ThrHis: 4.621 ± 1.909
0.924ThrIle: 0.924 ± 0.664
2.773ThrLys: 2.773 ± 1.365
3.697ThrLeu: 3.697 ± 1.377
0.924ThrMet: 0.924 ± 0.664
2.773ThrAsn: 2.773 ± 1.214
3.697ThrPro: 3.697 ± 1.377
4.621ThrGln: 4.621 ± 1.545
0.924ThrArg: 0.924 ± 0.756
4.621ThrSer: 4.621 ± 2.577
0.0ThrThr: 0.0 ± 0.0
4.621ThrVal: 4.621 ± 1.913
0.924ThrTrp: 0.924 ± 0.983
1.848ThrTyr: 1.848 ± 1.029
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
4.621ValAsp: 4.621 ± 1.074
3.697ValGlu: 3.697 ± 2.123
2.773ValPhe: 2.773 ± 1.331
1.848ValGly: 1.848 ± 1.108
2.773ValHis: 2.773 ± 1.325
5.545ValIle: 5.545 ± 2.072
5.545ValLys: 5.545 ± 1.889
3.697ValLeu: 3.697 ± 2.218
2.773ValMet: 2.773 ± 1.365
3.697ValAsn: 3.697 ± 2.731
4.621ValPro: 4.621 ± 1.074
7.394ValGln: 7.394 ± 2.561
3.697ValArg: 3.697 ± 2.278
4.621ValSer: 4.621 ± 1.483
3.697ValThr: 3.697 ± 2.071
2.773ValVal: 2.773 ± 1.955
0.0ValTrp: 0.0 ± 0.0
7.394ValTyr: 7.394 ± 2.819
0.0ValXaa: 0.0 ± 0.0
Trp
3.697TrpAla: 3.697 ± 1.802
0.0TrpCys: 0.0 ± 0.0
0.924TrpAsp: 0.924 ± 1.056
0.924TrpGlu: 0.924 ± 0.983
0.0TrpPhe: 0.0 ± 0.0
0.924TrpGly: 0.924 ± 0.664
0.924TrpHis: 0.924 ± 0.756
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.848TrpMet: 1.848 ± 1.109
0.924TrpAsn: 0.924 ± 0.983
0.0TrpPro: 0.0 ± 0.0
0.924TrpGln: 0.924 ± 0.664
0.924TrpArg: 0.924 ± 0.934
0.924TrpSer: 0.924 ± 0.934
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.924TrpTyr: 0.924 ± 0.664
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.773TyrAla: 2.773 ± 2.268
0.0TyrCys: 0.0 ± 0.0
1.848TyrAsp: 1.848 ± 1.181
0.924TyrGlu: 0.924 ± 0.756
1.848TyrPhe: 1.848 ± 1.109
1.848TyrGly: 1.848 ± 0.944
0.924TyrHis: 0.924 ± 0.664
1.848TyrIle: 1.848 ± 1.329
0.924TyrLys: 0.924 ± 0.664
4.621TyrLeu: 4.621 ± 1.334
1.848TyrMet: 1.848 ± 1.06
2.773TyrAsn: 2.773 ± 0.953
0.924TyrPro: 0.924 ± 0.664
0.924TyrGln: 0.924 ± 0.756
1.848TyrArg: 1.848 ± 1.512
3.697TyrSer: 3.697 ± 1.47
1.848TyrThr: 1.848 ± 1.313
5.545TyrVal: 5.545 ± 1.229
0.0TyrTrp: 0.0 ± 0.0
0.924TyrTyr: 0.924 ± 0.934
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1083 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski