Human polyomavirus 6

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Sepolyvirales; Polyomaviridae; Deltapolyomavirus

Average proteome isoelectric point is 5.87

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|D6QWF4|D6QWF4_9POLY VP3 OS=Human polyomavirus 6 OX=746830 GN=HPyV6_gp2 PE=4 SV=1
MM1 pKa = 7.81GILFSLPEE9 pKa = 4.83IIAAAAVGGGEE20 pKa = 4.1ALEE23 pKa = 4.18IAGGLGALVSGEE35 pKa = 3.94GLATLEE41 pKa = 4.35ALQSAAALSSEE52 pKa = 4.05ATAALAVSNEE62 pKa = 3.62AAIVLSTVPEE72 pKa = 4.43LSQTLFGAQLLLSSVAGVGGVIYY95 pKa = 10.68SNYY98 pKa = 10.13NPGEE102 pKa = 4.13LYY104 pKa = 10.31KK105 pKa = 10.93APEE108 pKa = 4.7GPGGLGPRR116 pKa = 11.84VGNTTMALQLWLPQVWSWGGAGRR139 pKa = 11.84GLPDD143 pKa = 3.21WLINMLRR150 pKa = 11.84EE151 pKa = 4.35VPSPTEE157 pKa = 3.55ILSDD161 pKa = 3.35IVRR164 pKa = 11.84GIWTSYY170 pKa = 8.46YY171 pKa = 9.54RR172 pKa = 11.84AGRR175 pKa = 11.84EE176 pKa = 3.87IIQRR180 pKa = 11.84TASRR184 pKa = 11.84EE185 pKa = 3.91LGALLSRR192 pKa = 11.84VRR194 pKa = 11.84EE195 pKa = 4.24TVIHH199 pKa = 5.23GAEE202 pKa = 4.13RR203 pKa = 11.84ALEE206 pKa = 4.13AAPDD210 pKa = 4.01PVQGLVNLVNYY221 pKa = 8.98AVNYY225 pKa = 7.66NRR227 pKa = 11.84QWEE230 pKa = 4.4TRR232 pKa = 11.84ALLEE236 pKa = 4.26GRR238 pKa = 11.84PLFEE242 pKa = 4.91GNGVVNYY249 pKa = 10.64DD250 pKa = 3.69MQNLPVNGNNDD261 pKa = 3.3QRR263 pKa = 11.84GGFHH267 pKa = 7.9DD268 pKa = 3.85EE269 pKa = 4.17GLWVSFSAEE278 pKa = 3.81QGNTGQYY285 pKa = 10.18CIPQWLLFVLEE296 pKa = 4.64EE297 pKa = 3.97LDD299 pKa = 4.93KK300 pKa = 11.04EE301 pKa = 4.35IKK303 pKa = 10.18EE304 pKa = 4.3DD305 pKa = 3.66ALSQKK310 pKa = 10.54RR311 pKa = 11.84KK312 pKa = 4.54WTNSKK317 pKa = 10.65ASQSNKK323 pKa = 8.57KK324 pKa = 9.45RR325 pKa = 11.84RR326 pKa = 11.84SGGYY330 pKa = 9.79GNSATFF336 pKa = 3.47

Molecular weight: 35.97 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|D6QWG7|D6QWG7_9POLY Small T antigen OS=Human polyomavirus 6 OX=746830 GN=HPyV6_gp5 PE=4 SV=1
MM1 pKa = 7.86DD2 pKa = 5.45RR3 pKa = 11.84LLARR7 pKa = 11.84EE8 pKa = 4.09EE9 pKa = 3.96VRR11 pKa = 11.84EE12 pKa = 3.89LMDD15 pKa = 6.04LIGLSMACWGNLPLMQQKK33 pKa = 9.33IRR35 pKa = 11.84LACKK39 pKa = 9.98KK40 pKa = 8.36YY41 pKa = 10.54HH42 pKa = 6.79PDD44 pKa = 3.75KK45 pKa = 11.52GGDD48 pKa = 3.58PEE50 pKa = 4.68KK51 pKa = 10.14MQRR54 pKa = 11.84LNVLKK59 pKa = 10.4EE60 pKa = 3.93KK61 pKa = 11.09LNATLRR67 pKa = 11.84DD68 pKa = 3.79QMSSSPTWCFSSEE81 pKa = 4.05VSDD84 pKa = 3.72DD85 pKa = 2.91WGIPLTVGEE94 pKa = 4.14FLGPEE99 pKa = 3.88FHH101 pKa = 7.38KK102 pKa = 11.02KK103 pKa = 9.91KK104 pKa = 10.46VWDD107 pKa = 4.08FRR109 pKa = 11.84LCVQQGISSCKK120 pKa = 9.89CLHH123 pKa = 6.4CLLKK127 pKa = 10.53KK128 pKa = 8.08EE129 pKa = 4.42HH130 pKa = 6.6KK131 pKa = 9.97KK132 pKa = 10.13QVEE135 pKa = 4.12INLGKK140 pKa = 7.92PTIWGKK146 pKa = 8.79CWCYY150 pKa = 10.94KK151 pKa = 10.28CYY153 pKa = 10.39CLWFGLPVEE162 pKa = 5.11ADD164 pKa = 2.99SFMWWTHH171 pKa = 6.45IIYY174 pKa = 10.07QSPLDD179 pKa = 3.47WLGITEE185 pKa = 4.93KK186 pKa = 10.95LIWWW190 pKa = 4.08

Molecular weight: 22.36 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

1797

190

669

359.4

40.03

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.346 ± 0.964

2.671 ± 0.982

4.452 ± 0.835

6.678 ± 0.323

3.395 ± 0.436

8.013 ± 1.33

1.447 ± 0.376

4.452 ± 0.197

5.398 ± 1.237

10.239 ± 0.962

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.449 ± 0.398

4.953 ± 0.509

5.287 ± 0.818

5.064 ± 0.296

4.619 ± 0.682

6.511 ± 0.253

5.064 ± 0.571

6.4 ± 0.68

2.56 ± 0.727

3.005 ± 0.148
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski