Amino acid dipepetide frequency for Shuangao alphatetra-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.667AlaAla: 6.667 ± 0.514
0.0AlaCys: 0.0 ± 0.0
3.75AlaAsp: 3.75 ± 1.895
3.75AlaGlu: 3.75 ± 1.107
2.5AlaPhe: 2.5 ± 2.111
2.917AlaGly: 2.917 ± 1.559
0.417AlaHis: 0.417 ± 0.242
4.167AlaIle: 4.167 ± 1.84
3.333AlaLys: 3.333 ± 0.95
8.75AlaLeu: 8.75 ± 2.574
1.25AlaMet: 1.25 ± 0.701
3.75AlaAsn: 3.75 ± 0.898
4.583AlaPro: 4.583 ± 3.263
2.5AlaGln: 2.5 ± 0.947
2.083AlaArg: 2.083 ± 0.545
4.167AlaSer: 4.167 ± 1.564
5.0AlaThr: 5.0 ± 2.192
4.167AlaVal: 4.167 ± 3.119
1.25AlaTrp: 1.25 ± 1.078
2.917AlaTyr: 2.917 ± 2.584
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.833CysAsp: 0.833 ± 0.484
0.417CysGlu: 0.417 ± 0.242
0.417CysPhe: 0.417 ± 0.242
0.417CysGly: 0.417 ± 0.242
1.25CysHis: 1.25 ± 0.793
0.833CysIle: 0.833 ± 0.484
0.0CysLys: 0.0 ± 0.0
0.833CysLeu: 0.833 ± 1.141
0.0CysMet: 0.0 ± 0.0
0.833CysAsn: 0.833 ± 0.839
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.667CysSer: 1.667 ± 1.081
1.667CysThr: 1.667 ± 0.572
0.833CysVal: 0.833 ± 0.484
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.583AspAla: 4.583 ± 3.018
0.833AspCys: 0.833 ± 0.484
5.833AspAsp: 5.833 ± 2.044
6.25AspGlu: 6.25 ± 1.007
2.083AspPhe: 2.083 ± 1.211
3.333AspGly: 3.333 ± 2.253
0.833AspHis: 0.833 ± 0.484
7.083AspIle: 7.083 ± 4.473
5.833AspLys: 5.833 ± 1.475
4.583AspLeu: 4.583 ± 2.097
0.833AspMet: 0.833 ± 0.489
2.083AspAsn: 2.083 ± 0.911
2.083AspPro: 2.083 ± 0.739
4.167AspGln: 4.167 ± 0.945
2.5AspArg: 2.5 ± 0.94
6.667AspSer: 6.667 ± 1.77
0.833AspThr: 0.833 ± 0.484
3.333AspVal: 3.333 ± 1.395
0.0AspTrp: 0.0 ± 0.0
2.083AspTyr: 2.083 ± 0.92
0.0AspXaa: 0.0 ± 0.0
Glu
1.667GluAla: 1.667 ± 0.968
0.417GluCys: 0.417 ± 0.242
1.25GluAsp: 1.25 ± 0.726
2.083GluGlu: 2.083 ± 0.739
0.417GluPhe: 0.417 ± 0.242
2.083GluGly: 2.083 ± 1.131
0.417GluHis: 0.417 ± 0.242
4.583GluIle: 4.583 ± 1.674
2.917GluLys: 2.917 ± 1.022
3.333GluLeu: 3.333 ± 0.977
1.667GluMet: 1.667 ± 0.968
4.167GluAsn: 4.167 ± 2.075
3.75GluPro: 3.75 ± 2.159
3.75GluGln: 3.75 ± 1.299
2.5GluArg: 2.5 ± 0.94
2.5GluSer: 2.5 ± 0.875
2.5GluThr: 2.5 ± 1.126
1.25GluVal: 1.25 ± 1.078
1.25GluTrp: 1.25 ± 1.606
2.5GluTyr: 2.5 ± 1.453
0.0GluXaa: 0.0 ± 0.0
Phe
3.333PheAla: 3.333 ± 1.952
0.417PheCys: 0.417 ± 0.242
2.917PheAsp: 2.917 ± 1.225
0.417PheGlu: 0.417 ± 0.242
1.25PhePhe: 1.25 ± 0.474
3.333PheGly: 3.333 ± 0.583
1.25PheHis: 1.25 ± 0.726
3.75PheIle: 3.75 ± 0.898
4.583PheLys: 4.583 ± 0.981
2.5PheLeu: 2.5 ± 2.131
1.667PheMet: 1.667 ± 0.572
2.083PheAsn: 2.083 ± 1.395
1.667PhePro: 1.667 ± 2.376
0.833PheGln: 0.833 ± 0.484
2.083PheArg: 2.083 ± 0.92
0.417PheSer: 0.417 ± 0.946
2.917PheThr: 2.917 ± 3.944
1.25PheVal: 1.25 ± 1.772
0.417PheTrp: 0.417 ± 0.242
1.25PheTyr: 1.25 ± 1.828
0.0PheXaa: 0.0 ± 0.0
Gly
5.417GlyAla: 5.417 ± 1.938
0.833GlyCys: 0.833 ± 0.489
5.417GlyAsp: 5.417 ± 2.554
2.5GlyGlu: 2.5 ± 2.131
2.917GlyPhe: 2.917 ± 1.501
5.0GlyGly: 5.0 ± 3.03
0.833GlyHis: 0.833 ± 1.141
4.583GlyIle: 4.583 ± 1.864
2.917GlyLys: 2.917 ± 0.594
2.917GlyLeu: 2.917 ± 0.998
2.5GlyMet: 2.5 ± 1.453
2.917GlyAsn: 2.917 ± 1.334
1.667GlyPro: 1.667 ± 1.57
3.75GlyGln: 3.75 ± 1.299
2.5GlyArg: 2.5 ± 0.947
3.333GlySer: 3.333 ± 1.335
2.083GlyThr: 2.083 ± 1.003
2.5GlyVal: 2.5 ± 1.467
0.0GlyTrp: 0.0 ± 0.0
2.083GlyTyr: 2.083 ± 0.932
0.0GlyXaa: 0.0 ± 0.0
His
1.25HisAla: 1.25 ± 2.374
0.833HisCys: 0.833 ± 0.484
1.25HisAsp: 1.25 ± 0.726
0.833HisGlu: 0.833 ± 0.484
0.833HisPhe: 0.833 ± 0.484
1.25HisGly: 1.25 ± 0.726
0.833HisHis: 0.833 ± 0.484
0.417HisIle: 0.417 ± 0.609
1.25HisLys: 1.25 ± 0.726
0.833HisLeu: 0.833 ± 0.839
0.417HisMet: 0.417 ± 0.242
1.25HisAsn: 1.25 ± 0.793
0.833HisPro: 0.833 ± 0.484
1.667HisGln: 1.667 ± 0.819
0.417HisArg: 0.417 ± 0.242
2.083HisSer: 2.083 ± 0.911
2.083HisThr: 2.083 ± 1.211
1.25HisVal: 1.25 ± 0.793
0.0HisTrp: 0.0 ± 0.0
3.333HisTyr: 3.333 ± 1.937
0.0HisXaa: 0.0 ± 0.0
Ile
6.667IleAla: 6.667 ± 1.102
0.417IleCys: 0.417 ± 0.946
5.0IleAsp: 5.0 ± 1.103
4.583IleGlu: 4.583 ± 1.674
1.667IlePhe: 1.667 ± 0.667
5.417IleGly: 5.417 ± 1.03
0.833IleHis: 0.833 ± 0.839
6.667IleIle: 6.667 ± 1.93
5.833IleLys: 5.833 ± 2.313
6.25IleLeu: 6.25 ± 3.632
0.833IleMet: 0.833 ± 0.421
8.333IleAsn: 8.333 ± 2.311
2.917IlePro: 2.917 ± 1.559
1.25IleGln: 1.25 ± 0.843
3.75IleArg: 3.75 ± 2.799
2.917IleSer: 2.917 ± 1.333
7.083IleThr: 7.083 ± 2.266
5.417IleVal: 5.417 ± 1.255
0.833IleTrp: 0.833 ± 0.489
4.583IleTyr: 4.583 ± 1.489
0.0IleXaa: 0.0 ± 0.0
Lys
2.5LysAla: 2.5 ± 0.947
1.25LysCys: 1.25 ± 0.726
2.5LysAsp: 2.5 ± 0.516
4.167LysGlu: 4.167 ± 1.84
1.25LysPhe: 1.25 ± 0.793
1.25LysGly: 1.25 ± 0.726
2.5LysHis: 2.5 ± 1.453
6.25LysIle: 6.25 ± 1.744
2.083LysLys: 2.083 ± 0.739
5.0LysLeu: 5.0 ± 1.979
0.833LysMet: 0.833 ± 0.484
3.333LysAsn: 3.333 ± 1.937
3.333LysPro: 3.333 ± 0.745
2.917LysGln: 2.917 ± 1.36
2.917LysArg: 2.917 ± 0.896
3.75LysSer: 3.75 ± 1.299
5.0LysThr: 5.0 ± 2.317
2.917LysVal: 2.917 ± 0.667
0.833LysTrp: 0.833 ± 1.219
3.75LysTyr: 3.75 ± 0.898
0.0LysXaa: 0.0 ± 0.0
Leu
4.583LeuAla: 4.583 ± 0.981
0.417LeuCys: 0.417 ± 0.242
6.25LeuAsp: 6.25 ± 1.326
4.583LeuGlu: 4.583 ± 1.033
2.917LeuPhe: 2.917 ± 0.896
4.583LeuGly: 4.583 ± 1.04
2.083LeuHis: 2.083 ± 1.211
4.583LeuIle: 4.583 ± 2.407
6.667LeuLys: 6.667 ± 3.041
3.75LeuLeu: 3.75 ± 0.936
0.833LeuMet: 0.833 ± 0.484
3.333LeuAsn: 3.333 ± 1.382
2.083LeuPro: 2.083 ± 1.287
3.333LeuGln: 3.333 ± 3.236
6.25LeuArg: 6.25 ± 2.537
4.583LeuSer: 4.583 ± 0.854
8.75LeuThr: 8.75 ± 1.6
2.917LeuVal: 2.917 ± 0.896
0.417LeuTrp: 0.417 ± 0.242
4.167LeuTyr: 4.167 ± 0.909
0.0LeuXaa: 0.0 ± 0.0
Met
2.5MetAla: 2.5 ± 1.126
0.0MetCys: 0.0 ± 0.0
2.917MetAsp: 2.917 ± 1.695
1.25MetGlu: 1.25 ± 0.726
1.25MetPhe: 1.25 ± 0.474
1.667MetGly: 1.667 ± 0.572
0.833MetHis: 0.833 ± 0.839
1.667MetIle: 1.667 ± 0.968
0.833MetLys: 0.833 ± 0.484
1.25MetLeu: 1.25 ± 0.726
0.0MetMet: 0.0 ± 0.0
1.25MetAsn: 1.25 ± 1.078
0.417MetPro: 0.417 ± 0.946
1.25MetGln: 1.25 ± 1.085
1.25MetArg: 1.25 ± 0.474
0.0MetSer: 0.0 ± 0.0
1.25MetThr: 1.25 ± 0.474
1.25MetVal: 1.25 ± 0.726
1.25MetTrp: 1.25 ± 0.726
0.833MetTyr: 0.833 ± 0.484
0.0MetXaa: 0.0 ± 0.0
Asn
4.583AsnAla: 4.583 ± 1.78
0.833AsnCys: 0.833 ± 0.484
5.833AsnAsp: 5.833 ± 1.331
3.333AsnGlu: 3.333 ± 1.143
4.167AsnPhe: 4.167 ± 3.083
3.75AsnGly: 3.75 ± 1.591
1.667AsnHis: 1.667 ± 0.968
7.917AsnIle: 7.917 ± 1.364
1.667AsnLys: 1.667 ± 0.978
8.333AsnLeu: 8.333 ± 2.541
1.25AsnMet: 1.25 ± 1.129
5.417AsnAsn: 5.417 ± 2.761
1.25AsnPro: 1.25 ± 1.772
2.917AsnGln: 2.917 ± 1.333
1.667AsnArg: 1.667 ± 2.376
4.583AsnSer: 4.583 ± 3.018
3.75AsnThr: 3.75 ± 2.159
5.0AsnVal: 5.0 ± 0.942
0.417AsnTrp: 0.417 ± 0.242
4.583AsnTyr: 4.583 ± 0.912
0.0AsnXaa: 0.0 ± 0.0
Pro
2.917ProAla: 2.917 ± 2.648
0.417ProCys: 0.417 ± 0.242
3.333ProAsp: 3.333 ± 1.084
1.667ProGlu: 1.667 ± 0.968
1.25ProPhe: 1.25 ± 1.606
3.75ProGly: 3.75 ± 1.591
0.417ProHis: 0.417 ± 0.242
3.75ProIle: 3.75 ± 1.919
2.5ProLys: 2.5 ± 1.453
3.75ProLeu: 3.75 ± 0.877
0.833ProMet: 0.833 ± 0.484
3.75ProAsn: 3.75 ± 1.421
0.833ProPro: 0.833 ± 0.489
2.5ProGln: 2.5 ± 2.131
0.417ProArg: 0.417 ± 0.946
2.917ProSer: 2.917 ± 2.565
3.75ProThr: 3.75 ± 2.208
2.5ProVal: 2.5 ± 1.204
0.0ProTrp: 0.0 ± 0.0
2.083ProTyr: 2.083 ± 2.24
0.0ProXaa: 0.0 ± 0.0
Gln
4.167GlnAla: 4.167 ± 1.864
0.0GlnCys: 0.0 ± 0.0
1.667GlnAsp: 1.667 ± 0.978
0.833GlnGlu: 0.833 ± 0.484
2.917GlnPhe: 2.917 ± 3.709
1.667GlnGly: 1.667 ± 0.667
1.25GlnHis: 1.25 ± 0.726
5.0GlnIle: 5.0 ± 1.75
1.25GlnLys: 1.25 ± 0.793
3.75GlnLeu: 3.75 ± 1.716
0.417GlnMet: 0.417 ± 0.242
5.417GlnAsn: 5.417 ± 1.938
3.75GlnPro: 3.75 ± 2.496
1.25GlnGln: 1.25 ± 1.085
1.667GlnArg: 1.667 ± 0.968
2.917GlnSer: 2.917 ± 1.695
2.917GlnThr: 2.917 ± 0.998
2.917GlnVal: 2.917 ± 1.022
0.0GlnTrp: 0.0 ± 0.0
0.833GlnTyr: 0.833 ± 0.839
0.0GlnXaa: 0.0 ± 0.0
Arg
2.5ArgAla: 2.5 ± 1.453
1.25ArgCys: 1.25 ± 1.085
2.083ArgAsp: 2.083 ± 1.884
1.25ArgGlu: 1.25 ± 1.085
2.083ArgPhe: 2.083 ± 0.545
3.333ArgGly: 3.333 ± 1.143
1.25ArgHis: 1.25 ± 0.474
5.0ArgIle: 5.0 ± 1.103
2.083ArgLys: 2.083 ± 1.211
1.667ArgLeu: 1.667 ± 0.572
1.25ArgMet: 1.25 ± 0.726
4.583ArgAsn: 4.583 ± 1.652
2.083ArgPro: 2.083 ± 0.545
0.833ArgGln: 0.833 ± 0.484
2.083ArgArg: 2.083 ± 0.932
1.667ArgSer: 1.667 ± 0.572
2.917ArgThr: 2.917 ± 0.896
3.333ArgVal: 3.333 ± 1.143
0.0ArgTrp: 0.0 ± 0.0
4.167ArgTyr: 4.167 ± 2.075
0.0ArgXaa: 0.0 ± 0.0
Ser
2.917SerAla: 2.917 ± 0.667
0.0SerCys: 0.0 ± 0.0
3.333SerAsp: 3.333 ± 1.084
2.5SerGlu: 2.5 ± 0.94
2.083SerPhe: 2.083 ± 3.241
5.417SerGly: 5.417 ± 2.113
0.0SerHis: 0.0 ± 0.0
2.917SerIle: 2.917 ± 1.157
2.917SerLys: 2.917 ± 1.594
4.583SerLeu: 4.583 ± 1.69
2.917SerMet: 2.917 ± 0.998
5.417SerAsn: 5.417 ± 2.772
2.917SerPro: 2.917 ± 0.667
3.333SerGln: 3.333 ± 0.583
2.5SerArg: 2.5 ± 1.467
5.0SerSer: 5.0 ± 2.196
3.75SerThr: 3.75 ± 2.208
3.333SerVal: 3.333 ± 1.143
0.833SerTrp: 0.833 ± 0.484
4.167SerTyr: 4.167 ± 0.695
0.0SerXaa: 0.0 ± 0.0
Thr
4.583ThrAla: 4.583 ± 1.652
0.417ThrCys: 0.417 ± 0.946
3.333ThrAsp: 3.333 ± 1.395
1.25ThrGlu: 1.25 ± 1.167
2.917ThrPhe: 2.917 ± 2.18
2.083ThrGly: 2.083 ± 0.739
2.083ThrHis: 2.083 ± 1.395
5.0ThrIle: 5.0 ± 2.002
6.25ThrLys: 6.25 ± 1.327
6.667ThrLeu: 6.667 ± 1.577
2.917ThrMet: 2.917 ± 1.695
5.0ThrAsn: 5.0 ± 1.632
4.167ThrPro: 4.167 ± 3.45
2.917ThrGln: 2.917 ± 1.411
4.583ThrArg: 4.583 ± 0.854
3.75ThrSer: 3.75 ± 1.194
4.583ThrThr: 4.583 ± 2.424
3.75ThrVal: 3.75 ± 1.74
0.417ThrTrp: 0.417 ± 0.242
4.583ThrTyr: 4.583 ± 0.854
0.0ThrXaa: 0.0 ± 0.0
Val
3.75ValAla: 3.75 ± 1.74
0.833ValCys: 0.833 ± 0.484
2.917ValAsp: 2.917 ± 1.96
2.083ValGlu: 2.083 ± 0.92
2.083ValPhe: 2.083 ± 0.739
2.083ValGly: 2.083 ± 0.932
2.083ValHis: 2.083 ± 0.911
3.333ValIle: 3.333 ± 1.382
3.333ValLys: 3.333 ± 1.382
5.0ValLeu: 5.0 ± 2.049
1.667ValMet: 1.667 ± 0.667
5.0ValAsn: 5.0 ± 2.341
2.5ValPro: 2.5 ± 0.947
2.917ValGln: 2.917 ± 0.667
1.25ValArg: 1.25 ± 0.843
1.667ValSer: 1.667 ± 0.978
4.583ValThr: 4.583 ± 1.674
2.083ValVal: 2.083 ± 0.932
0.417ValTrp: 0.417 ± 0.242
2.917ValTyr: 2.917 ± 1.411
0.0ValXaa: 0.0 ± 0.0
Trp
0.833TrpAla: 0.833 ± 0.484
0.0TrpCys: 0.0 ± 0.0
0.417TrpAsp: 0.417 ± 0.609
0.833TrpGlu: 0.833 ± 0.489
0.417TrpPhe: 0.417 ± 0.242
0.0TrpGly: 0.0 ± 0.0
0.833TrpHis: 0.833 ± 0.484
0.833TrpIle: 0.833 ± 1.046
0.417TrpLys: 0.417 ± 1.243
1.25TrpLeu: 1.25 ± 0.726
0.0TrpMet: 0.0 ± 0.0
0.417TrpAsn: 0.417 ± 0.609
0.417TrpPro: 0.417 ± 0.242
0.0TrpGln: 0.0 ± 0.0
0.417TrpArg: 0.417 ± 0.242
0.417TrpSer: 0.417 ± 0.609
0.417TrpThr: 0.417 ± 0.609
1.25TrpVal: 1.25 ± 0.474
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.5TyrAla: 2.5 ± 2.111
0.833TyrCys: 0.833 ± 1.141
5.0TyrAsp: 5.0 ± 1.115
0.417TyrGlu: 0.417 ± 0.609
2.917TyrPhe: 2.917 ± 1.225
3.333TyrGly: 3.333 ± 1.168
1.25TyrHis: 1.25 ± 0.726
2.917TyrIle: 2.917 ± 0.667
1.667TyrLys: 1.667 ± 0.968
2.083TyrLeu: 2.083 ± 0.545
0.417TyrMet: 0.417 ± 0.878
4.583TyrAsn: 4.583 ± 0.854
2.083TyrPro: 2.083 ± 0.545
2.5TyrGln: 2.5 ± 0.94
4.583TyrArg: 4.583 ± 0.854
5.833TyrSer: 5.833 ± 2.952
5.417TyrThr: 5.417 ± 0.542
1.25TyrVal: 1.25 ± 0.726
0.833TyrTrp: 0.833 ± 1.219
3.333TyrTyr: 3.333 ± 1.638
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2401 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski