Amino acid dipepetide frequency for Colinus virginianus (Northern bobwhite) (Tetrao virginianus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.747AlaAla: 7.747 ± 0.062	1.374AlaCys: 1.374 ± 0.015	3.246AlaAsp: 3.246 ± 0.023	5.37AlaGlu: 5.37 ± 0.033	2.661AlaPhe: 2.661 ± 0.021	4.741AlaGly: 4.741 ± 0.032	1.428AlaHis: 1.428 ± 0.014	2.919AlaIle: 2.919 ± 0.023	3.649AlaLys: 3.649 ± 0.029	7.103AlaLeu: 7.103 ± 0.047	1.573AlaMet: 1.573 ± 0.014	2.179AlaAsn: 2.179 ± 0.018	3.506AlaPro: 3.506 ± 0.032	2.953AlaGln: 2.953 ± 0.024	3.461AlaArg: 3.461 ± 0.027	5.435AlaSer: 5.435 ± 0.027	3.405AlaThr: 3.405 ± 0.027	5.476AlaVal: 5.476 ± 0.03	0.768AlaTrp: 0.768 ± 0.01	1.632AlaTyr: 1.632 ± 0.013	0.003AlaXaa: 0.003 ± 0.001
Cys	1.309CysAla: 1.309 ± 0.017	0.669CysCys: 0.669 ± 0.011	1.056CysAsp: 1.056 ± 0.016	1.325CysGlu: 1.325 ± 0.017	0.912CysPhe: 0.912 ± 0.011	1.506CysGly: 1.506 ± 0.016	0.63CysHis: 0.63 ± 0.011	1.05CysIle: 1.05 ± 0.015	1.239CysLys: 1.239 ± 0.016	2.145CysLeu: 2.145 ± 0.02	0.461CysMet: 0.461 ± 0.008	0.852CysAsn: 0.852 ± 0.013	1.296CysPro: 1.296 ± 0.018	1.051CysGln: 1.051 ± 0.014	1.311CysArg: 1.311 ± 0.014	2.087CysSer: 2.087 ± 0.019	1.178CysThr: 1.178 ± 0.013	1.428CysVal: 1.428 ± 0.017	0.306CysTrp: 0.306 ± 0.007	0.645CysTyr: 0.645 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.189AspAla: 3.189 ± 0.021	1.1AspCys: 1.1 ± 0.014	2.795AspAsp: 2.795 ± 0.029	3.73AspGlu: 3.73 ± 0.03	2.197AspPhe: 2.197 ± 0.021	3.491AspGly: 3.491 ± 0.029	1.081AspHis: 1.081 ± 0.011	2.797AspIle: 2.797 ± 0.021	2.663AspLys: 2.663 ± 0.023	4.871AspLeu: 4.871 ± 0.031	1.17AspMet: 1.17 ± 0.013	1.834AspAsn: 1.834 ± 0.02	2.742AspPro: 2.742 ± 0.026	1.711AspGln: 1.711 ± 0.016	2.409AspArg: 2.409 ± 0.019	4.202AspSer: 4.202 ± 0.031	2.528AspThr: 2.528 ± 0.023	3.402AspVal: 3.402 ± 0.029	0.603AspTrp: 0.603 ± 0.01	1.555AspTyr: 1.555 ± 0.016	0.001AspXaa: 0.001 ± 0.0
Glu	5.072GluAla: 5.072 ± 0.034	1.301GluCys: 1.301 ± 0.023	4.547GluAsp: 4.547 ± 0.03	8.425GluGlu: 8.425 ± 0.068	2.114GluPhe: 2.114 ± 0.017	4.109GluGly: 4.109 ± 0.027	1.612GluHis: 1.612 ± 0.015	3.344GluIle: 3.344 ± 0.022	5.577GluLys: 5.577 ± 0.044	6.692GluLeu: 6.692 ± 0.043	1.857GluMet: 1.857 ± 0.016	3.28GluAsn: 3.28 ± 0.025	2.934GluPro: 2.934 ± 0.026	3.378GluGln: 3.378 ± 0.028	4.183GluArg: 4.183 ± 0.037	4.537GluSer: 4.537 ± 0.034	3.465GluThr: 3.465 ± 0.03	4.41GluVal: 4.41 ± 0.029	0.737GluTrp: 0.737 ± 0.009	1.754GluTyr: 1.754 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.152PheAla: 2.152 ± 0.02	0.983PheCys: 0.983 ± 0.01	1.765PheAsp: 1.765 ± 0.016	2.077PheGlu: 2.077 ± 0.018	1.689PhePhe: 1.689 ± 0.017	2.25PheGly: 2.25 ± 0.021	1.049PheHis: 1.049 ± 0.012	1.928PheIle: 1.928 ± 0.018	1.818PheLys: 1.818 ± 0.018	4.04PheLeu: 4.04 ± 0.031	0.789PheMet: 0.789 ± 0.011	1.399PheAsn: 1.399 ± 0.012	1.954PhePro: 1.954 ± 0.018	1.773PheGln: 1.773 ± 0.016	1.916PheArg: 1.916 ± 0.02	3.383PheSer: 3.383 ± 0.022	2.075PheThr: 2.075 ± 0.017	2.366PheVal: 2.366 ± 0.019	0.49PheTrp: 0.49 ± 0.009	1.247PheTyr: 1.247 ± 0.015	0.001PheXaa: 0.001 ± 0.0
Gly	4.235GlyAla: 4.235 ± 0.033	1.324GlyCys: 1.324 ± 0.015	3.158GlyAsp: 3.158 ± 0.028	4.06GlyGlu: 4.06 ± 0.037	2.404GlyPhe: 2.404 ± 0.025	4.745GlyGly: 4.745 ± 0.04	1.57GlyHis: 1.57 ± 0.017	2.884GlyIle: 2.884 ± 0.023	3.811GlyLys: 3.811 ± 0.025	5.35GlyLeu: 5.35 ± 0.038	1.402GlyMet: 1.402 ± 0.016	2.471GlyAsn: 2.471 ± 0.018	3.153GlyPro: 3.153 ± 0.051	2.584GlyGln: 2.584 ± 0.022	3.59GlyArg: 3.59 ± 0.026	5.527GlySer: 5.527 ± 0.032	3.644GlyThr: 3.644 ± 0.027	3.603GlyVal: 3.603 ± 0.026	0.769GlyTrp: 0.769 ± 0.012	1.837GlyTyr: 1.837 ± 0.02	0.002GlyXaa: 0.002 ± 0.001
His	1.42HisAla: 1.42 ± 0.014	0.703HisCys: 0.703 ± 0.01	0.939HisAsp: 0.939 ± 0.013	1.369HisGlu: 1.369 ± 0.014	1.064HisPhe: 1.064 ± 0.011	1.561HisGly: 1.561 ± 0.016	0.828HisHis: 0.828 ± 0.012	1.234HisIle: 1.234 ± 0.014	1.276HisLys: 1.276 ± 0.013	2.69HisLeu: 2.69 ± 0.023	0.572HisMet: 0.572 ± 0.009	0.918HisAsn: 0.918 ± 0.013	1.507HisPro: 1.507 ± 0.017	1.107HisGln: 1.107 ± 0.012	1.497HisArg: 1.497 ± 0.014	2.19HisSer: 2.19 ± 0.02	1.249HisThr: 1.249 ± 0.014	1.549HisVal: 1.549 ± 0.015	0.335HisTrp: 0.335 ± 0.007	0.839HisTyr: 0.839 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	2.875IleAla: 2.875 ± 0.022	1.131IleCys: 1.131 ± 0.016	2.21IleAsp: 2.21 ± 0.021	2.743IleGlu: 2.743 ± 0.023	1.956IlePhe: 1.956 ± 0.018	2.316IleGly: 2.316 ± 0.022	1.248IleHis: 1.248 ± 0.013	2.452IleIle: 2.452 ± 0.022	2.716IleLys: 2.716 ± 0.021	4.568IleLeu: 4.568 ± 0.032	1.011IleMet: 1.011 ± 0.013	1.951IleAsn: 1.951 ± 0.018	2.644IlePro: 2.644 ± 0.022	2.263IleGln: 2.263 ± 0.019	2.439IleArg: 2.439 ± 0.018	3.901IleSer: 3.901 ± 0.023	2.693IleThr: 2.693 ± 0.026	2.788IleVal: 2.788 ± 0.024	0.538IleTrp: 0.538 ± 0.01	1.453IleTyr: 1.453 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.12LysAla: 4.12 ± 0.03	1.132LysCys: 1.132 ± 0.013	3.292LysAsp: 3.292 ± 0.027	5.396LysGlu: 5.396 ± 0.041	1.745LysPhe: 1.745 ± 0.017	3.322LysGly: 3.322 ± 0.037	1.469LysHis: 1.469 ± 0.015	2.874LysIle: 2.874 ± 0.021	4.966LysLys: 4.966 ± 0.045	5.381LysLeu: 5.381 ± 0.033	1.568LysMet: 1.568 ± 0.016	2.49LysAsn: 2.49 ± 0.021	2.896LysPro: 2.896 ± 0.021	2.814LysGln: 2.814 ± 0.024	3.445LysArg: 3.445 ± 0.022	4.018LysSer: 4.018 ± 0.029	3.087LysThr: 3.087 ± 0.023	3.601LysVal: 3.601 ± 0.026	0.626LysTrp: 0.626 ± 0.011	1.742LysTyr: 1.742 ± 0.02	0.001LysXaa: 0.001 ± 0.0
Leu	6.541LeuAla: 6.541 ± 0.036	2.294LeuCys: 2.294 ± 0.021	4.704LeuAsp: 4.704 ± 0.029	7.015LeuGlu: 7.015 ± 0.047	3.455LeuPhe: 3.455 ± 0.03	5.402LeuGly: 5.402 ± 0.034	2.682LeuHis: 2.682 ± 0.02	3.927LeuIle: 3.927 ± 0.024	5.986LeuLys: 5.986 ± 0.038	10.63LeuLeu: 10.63 ± 0.071	2.046LeuMet: 2.046 ± 0.019	3.616LeuAsn: 3.616 ± 0.022	5.57LeuPro: 5.57 ± 0.036	5.722LeuGln: 5.722 ± 0.041	5.749LeuArg: 5.749 ± 0.037	7.951LeuSer: 7.951 ± 0.039	4.827LeuThr: 4.827 ± 0.027	5.421LeuVal: 5.421 ± 0.036	1.085LeuTrp: 1.085 ± 0.012	2.663LeuTyr: 2.663 ± 0.021	0.002LeuXaa: 0.002 ± 0.0
Met	1.926MetAla: 1.926 ± 0.018	0.434MetCys: 0.434 ± 0.008	1.272MetAsp: 1.272 ± 0.013	1.961MetGlu: 1.961 ± 0.018	0.79MetPhe: 0.79 ± 0.011	1.303MetGly: 1.303 ± 0.013	0.498MetHis: 0.498 ± 0.008	0.887MetIle: 0.887 ± 0.012	1.548MetLys: 1.548 ± 0.014	2.073MetLeu: 2.073 ± 0.018	0.601MetMet: 0.601 ± 0.009	0.93MetAsn: 0.93 ± 0.012	1.088MetPro: 1.088 ± 0.015	1.019MetGln: 1.019 ± 0.013	1.127MetArg: 1.127 ± 0.011	1.618MetSer: 1.618 ± 0.016	1.094MetThr: 1.094 ± 0.013	1.423MetVal: 1.423 ± 0.013	0.246MetTrp: 0.246 ± 0.006	0.622MetTyr: 0.622 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.35AsnAla: 2.35 ± 0.02	0.92AsnCys: 0.92 ± 0.013	1.62AsnAsp: 1.62 ± 0.017	2.419AsnGlu: 2.419 ± 0.02	1.489AsnPhe: 1.489 ± 0.016	2.606AsnGly: 2.606 ± 0.024	0.915AsnHis: 0.915 ± 0.011	2.257AsnIle: 2.257 ± 0.017	2.318AsnLys: 2.318 ± 0.019	3.747AsnLeu: 3.747 ± 0.024	0.962AsnMet: 0.962 ± 0.013	1.64AsnAsn: 1.64 ± 0.017	2.115AsnPro: 2.115 ± 0.018	1.564AsnGln: 1.564 ± 0.016	1.889AsnArg: 1.889 ± 0.017	3.227AsnSer: 3.227 ± 0.024	2.071AsnThr: 2.071 ± 0.02	2.449AsnVal: 2.449 ± 0.02	0.456AsnTrp: 0.456 ± 0.008	1.183AsnTyr: 1.183 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.398ProAla: 4.398 ± 0.037	1.141ProCys: 1.141 ± 0.017	2.642ProAsp: 2.642 ± 0.023	4.066ProGlu: 4.066 ± 0.029	1.855ProPhe: 1.855 ± 0.018	4.236ProGly: 4.236 ± 0.064	1.31ProHis: 1.31 ± 0.014	1.883ProIle: 1.883 ± 0.021	2.705ProLys: 2.705 ± 0.034	4.731ProLeu: 4.731 ± 0.031	0.973ProMet: 0.973 ± 0.013	1.778ProAsn: 1.778 ± 0.019	4.873ProPro: 4.873 ± 0.056	2.434ProGln: 2.434 ± 0.024	2.837ProArg: 2.837 ± 0.025	5.018ProSer: 5.018 ± 0.039	2.717ProThr: 2.717 ± 0.022	3.731ProVal: 3.731 ± 0.028	0.587ProTrp: 0.587 ± 0.011	1.405ProTyr: 1.405 ± 0.015	0.003ProXaa: 0.003 ± 0.001
Gln	3.147GlnAla: 3.147 ± 0.026	0.957GlnCys: 0.957 ± 0.013	2.203GlnAsp: 2.203 ± 0.021	3.773GlnGlu: 3.773 ± 0.031	1.38GlnPhe: 1.38 ± 0.012	2.541GlnGly: 2.541 ± 0.023	1.35GlnHis: 1.35 ± 0.016	2.036GlnIle: 2.036 ± 0.017	3.025GlnLys: 3.025 ± 0.025	4.707GlnLeu: 4.707 ± 0.036	1.104GlnMet: 1.104 ± 0.014	1.895GlnAsn: 1.895 ± 0.019	2.472GlnPro: 2.472 ± 0.023	3.106GlnGln: 3.106 ± 0.036	2.777GlnArg: 2.777 ± 0.022	3.174GlnSer: 3.174 ± 0.024	2.212GlnThr: 2.212 ± 0.023	2.718GlnVal: 2.718 ± 0.023	0.521GlnTrp: 0.521 ± 0.009	1.227GlnTyr: 1.227 ± 0.013	0.001GlnXaa: 0.001 ± 0.0
Arg	3.821ArgAla: 3.821 ± 0.026	1.26ArgCys: 1.26 ± 0.016	2.801ArgAsp: 2.801 ± 0.023	3.929ArgGlu: 3.929 ± 0.03	1.929ArgPhe: 1.929 ± 0.016	3.358ArgGly: 3.358 ± 0.026	1.455ArgHis: 1.455 ± 0.016	2.488ArgIle: 2.488 ± 0.018	3.685ArgLys: 3.685 ± 0.026	5.122ArgLeu: 5.122 ± 0.031	1.262ArgMet: 1.262 ± 0.015	2.152ArgAsn: 2.152 ± 0.017	2.622ArgPro: 2.622 ± 0.019	2.542ArgGln: 2.542 ± 0.02	4.24ArgArg: 4.24 ± 0.035	4.218ArgSer: 4.218 ± 0.038	2.693ArgThr: 2.693 ± 0.022	3.195ArgVal: 3.195 ± 0.024	0.677ArgTrp: 0.677 ± 0.009	1.616ArgTyr: 1.616 ± 0.015	0.002ArgXaa: 0.002 ± 0.0
Ser	5.614SerAla: 5.614 ± 0.029	1.914SerCys: 1.914 ± 0.016	4.025SerAsp: 4.025 ± 0.03	5.26SerGlu: 5.26 ± 0.037	3.076SerPhe: 3.076 ± 0.022	5.241SerGly: 5.241 ± 0.031	1.99SerHis: 1.99 ± 0.019	3.459SerIle: 3.459 ± 0.026	4.258SerLys: 4.258 ± 0.028	7.793SerLeu: 7.793 ± 0.04	1.642SerMet: 1.642 ± 0.014	2.83SerAsn: 2.83 ± 0.021	5.353SerPro: 5.353 ± 0.045	3.578SerGln: 3.578 ± 0.03	4.26SerArg: 4.26 ± 0.031	9.318SerSer: 9.318 ± 0.07	4.555SerThr: 4.555 ± 0.03	5.245SerVal: 5.245 ± 0.031	0.969SerTrp: 0.969 ± 0.013	2.179SerTyr: 2.179 ± 0.019	0.002SerXaa: 0.002 ± 0.001
Thr	4.1ThrAla: 4.1 ± 0.03	1.268ThrCys: 1.268 ± 0.019	2.659ThrAsp: 2.659 ± 0.022	3.729ThrGlu: 3.729 ± 0.026	2.085ThrPhe: 2.085 ± 0.017	3.375ThrGly: 3.375 ± 0.027	1.123ThrHis: 1.123 ± 0.011	2.378ThrIle: 2.378 ± 0.023	2.713ThrLys: 2.713 ± 0.023	5.003ThrLeu: 5.003 ± 0.028	1.102ThrMet: 1.102 ± 0.013	1.827ThrAsn: 1.827 ± 0.018	3.088ThrPro: 3.088 ± 0.032	2.071ThrGln: 2.071 ± 0.02	2.344ThrArg: 2.344 ± 0.018	4.442ThrSer: 4.442 ± 0.033	2.872ThrThr: 2.872 ± 0.029	4.112ThrVal: 4.112 ± 0.031	0.662ThrTrp: 0.662 ± 0.012	1.475ThrTyr: 1.475 ± 0.016	0.001ThrXaa: 0.001 ± 0.0
Val	4.358ValAla: 4.358 ± 0.028	1.563ValCys: 1.563 ± 0.017	3.043ValAsp: 3.043 ± 0.026	4.14ValGlu: 4.14 ± 0.029	2.583ValPhe: 2.583 ± 0.019	3.522ValGly: 3.522 ± 0.027	1.548ValHis: 1.548 ± 0.014	3.04ValIle: 3.04 ± 0.021	3.66ValLys: 3.66 ± 0.03	6.668ValLeu: 6.668 ± 0.037	1.406ValMet: 1.406 ± 0.014	2.433ValAsn: 2.433 ± 0.019	3.75ValPro: 3.75 ± 0.025	2.884ValGln: 2.884 ± 0.023	3.222ValArg: 3.222 ± 0.021	5.101ValSer: 5.101 ± 0.031	3.896ValThr: 3.896 ± 0.036	4.342ValVal: 4.342 ± 0.036	0.731ValTrp: 0.731 ± 0.011	1.771ValTyr: 1.771 ± 0.016	0.002ValXaa: 0.002 ± 0.0
Trp	0.707TrpAla: 0.707 ± 0.01	0.249TrpCys: 0.249 ± 0.007	0.673TrpAsp: 0.673 ± 0.011	0.781TrpGlu: 0.781 ± 0.011	0.445TrpPhe: 0.445 ± 0.008	0.691TrpGly: 0.691 ± 0.011	0.298TrpHis: 0.298 ± 0.006	0.569TrpIle: 0.569 ± 0.009	0.822TrpLys: 0.822 ± 0.011	1.215TrpLeu: 1.215 ± 0.014	0.319TrpMet: 0.319 ± 0.006	0.521TrpAsn: 0.521 ± 0.009	0.441TrpPro: 0.441 ± 0.007	0.535TrpGln: 0.535 ± 0.008	0.691TrpArg: 0.691 ± 0.012	0.863TrpSer: 0.863 ± 0.012	0.617TrpThr: 0.617 ± 0.011	0.681TrpVal: 0.681 ± 0.01	0.19TrpTrp: 0.19 ± 0.006	0.361TrpTyr: 0.361 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.547TyrAla: 1.547 ± 0.015	0.734TyrCys: 0.734 ± 0.012	1.422TyrAsp: 1.422 ± 0.015	1.763TyrGlu: 1.763 ± 0.017	1.315TyrPhe: 1.315 ± 0.014	1.804TyrGly: 1.804 ± 0.021	0.764TyrHis: 0.764 ± 0.012	1.489TyrIle: 1.489 ± 0.018	1.548TyrLys: 1.548 ± 0.023	2.759TyrLeu: 2.759 ± 0.019	0.641TyrMet: 0.641 ± 0.009	1.199TyrAsn: 1.199 ± 0.014	1.313TyrPro: 1.313 ± 0.016	1.236TyrGln: 1.236 ± 0.012	1.681TyrArg: 1.681 ± 0.017	2.349TyrSer: 2.349 ± 0.021	1.553TyrThr: 1.553 ± 0.017	1.721TyrVal: 1.721 ± 0.017	0.371TyrTrp: 0.371 ± 0.009	1.043TyrTyr: 1.043 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.003XaaGly: 0.003 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.003XaaPro: 0.003 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.001	0.002XaaSer: 0.002 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.264XaaXaa: 0.264 ± 0.034

Statistics based on 17122 proteins (8269645 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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