Amino acid dipepetide frequency for Ureaplasma parvum serovar 3 (strain ATCC 700970)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.582AlaAla: 2.582 ± 0.174
0.421AlaCys: 0.421 ± 0.043
2.099AlaAsp: 2.099 ± 0.099
1.927AlaGlu: 1.927 ± 0.113
2.498AlaPhe: 2.498 ± 0.14
2.366AlaGly: 2.366 ± 0.25
0.983AlaHis: 0.983 ± 0.064
5.374AlaIle: 5.374 ± 0.221
5.212AlaLys: 5.212 ± 0.153
4.878AlaLeu: 4.878 ± 0.197
0.953AlaMet: 0.953 ± 0.072
4.492AlaAsn: 4.492 ± 0.203
1.247AlaPro: 1.247 ± 0.077
1.743AlaGln: 1.743 ± 0.097
1.734AlaArg: 1.734 ± 0.095
2.968AlaSer: 2.968 ± 0.15
2.762AlaThr: 2.762 ± 0.121
2.23AlaVal: 2.23 ± 0.112
0.386AlaTrp: 0.386 ± 0.041
2.16AlaTyr: 2.16 ± 0.094
0.0AlaXaa: 0.0 ± 0.0
Cys
0.342CysAla: 0.342 ± 0.038
0.114CysCys: 0.114 ± 0.043
0.356CysAsp: 0.356 ± 0.046
0.479CysGlu: 0.479 ± 0.048
0.54CysPhe: 0.54 ± 0.049
0.378CysGly: 0.378 ± 0.042
0.171CysHis: 0.171 ± 0.028
0.65CysIle: 0.65 ± 0.061
0.457CysLys: 0.457 ± 0.049
0.733CysLeu: 0.733 ± 0.069
0.083CysMet: 0.083 ± 0.019
0.347CysAsn: 0.347 ± 0.049
0.193CysPro: 0.193 ± 0.03
0.224CysGln: 0.224 ± 0.028
0.14CysArg: 0.14 ± 0.029
0.413CysSer: 0.413 ± 0.04
0.281CysThr: 0.281 ± 0.04
0.408CysVal: 0.408 ± 0.041
0.057CysTrp: 0.057 ± 0.016
0.277CysTyr: 0.277 ± 0.041
0.0CysXaa: 0.0 ± 0.0
Asp
2.687AspAla: 2.687 ± 0.104
0.338AspCys: 0.338 ± 0.04
3.381AspAsp: 3.381 ± 0.14
4.592AspGlu: 4.592 ± 0.177
3.807AspPhe: 3.807 ± 0.145
2.454AspGly: 2.454 ± 0.118
1.181AspHis: 1.181 ± 0.061
4.562AspIle: 4.562 ± 0.169
4.715AspLys: 4.715 ± 0.136
6.726AspLeu: 6.726 ± 0.189
0.672AspMet: 0.672 ± 0.048
4.311AspAsn: 4.311 ± 0.242
1.787AspPro: 1.787 ± 0.111
2.674AspGln: 2.674 ± 0.168
1.326AspArg: 1.326 ± 0.082
2.713AspSer: 2.713 ± 0.105
1.945AspThr: 1.945 ± 0.127
3.275AspVal: 3.275 ± 0.141
0.439AspTrp: 0.439 ± 0.049
3.223AspTyr: 3.223 ± 0.124
0.0AspXaa: 0.0 ± 0.0
Glu
2.836GluAla: 2.836 ± 0.106
0.338GluCys: 0.338 ± 0.04
2.678GluAsp: 2.678 ± 0.11
3.126GluGlu: 3.126 ± 0.161
3.122GluPhe: 3.122 ± 0.129
1.826GluGly: 1.826 ± 0.092
1.067GluHis: 1.067 ± 0.064
6.696GluIle: 6.696 ± 0.237
5.032GluLys: 5.032 ± 0.196
6.634GluLeu: 6.634 ± 0.186
1.089GluMet: 1.089 ± 0.081
4.992GluAsn: 4.992 ± 0.166
1.37GluPro: 1.37 ± 0.091
3.095GluGln: 3.095 ± 0.273
1.905GluArg: 1.905 ± 0.106
2.7GluSer: 2.7 ± 0.12
2.463GluThr: 2.463 ± 0.116
3.126GluVal: 3.126 ± 0.12
0.597GluTrp: 0.597 ± 0.055
2.863GluTyr: 2.863 ± 0.108
0.0GluXaa: 0.0 ± 0.0
Phe
2.696PheAla: 2.696 ± 0.135
0.408PheCys: 0.408 ± 0.05
3.732PheAsp: 3.732 ± 0.147
3.381PheGlu: 3.381 ± 0.135
2.498PhePhe: 2.498 ± 0.151
2.428PheGly: 2.428 ± 0.144
0.527PheHis: 0.527 ± 0.046
5.291PheIle: 5.291 ± 0.239
5.299PheLys: 5.299 ± 0.165
5.001PheLeu: 5.001 ± 0.228
0.834PheMet: 0.834 ± 0.064
4.966PheAsn: 4.966 ± 0.203
0.922PhePro: 0.922 ± 0.072
1.084PheGln: 1.084 ± 0.071
1.014PheArg: 1.014 ± 0.06
3.859PheSer: 3.859 ± 0.142
2.16PheThr: 2.16 ± 0.108
2.849PheVal: 2.849 ± 0.137
0.378PheTrp: 0.378 ± 0.045
2.27PheTyr: 2.27 ± 0.112
0.0PheXaa: 0.0 ± 0.0
Gly
2.318GlyAla: 2.318 ± 0.126
0.272GlyCys: 0.272 ± 0.04
2.055GlyAsp: 2.055 ± 0.104
1.949GlyGlu: 1.949 ± 0.098
2.604GlyPhe: 2.604 ± 0.129
2.323GlyGly: 2.323 ± 0.143
0.817GlyHis: 0.817 ± 0.074
4.632GlyIle: 4.632 ± 0.19
3.35GlyLys: 3.35 ± 0.271
4.496GlyLeu: 4.496 ± 0.197
0.878GlyMet: 0.878 ± 0.065
2.266GlyAsn: 2.266 ± 0.103
0.918GlyPro: 0.918 ± 0.061
1.392GlyGln: 1.392 ± 0.072
1.234GlyArg: 1.234 ± 0.091
2.7GlySer: 2.7 ± 0.144
2.107GlyThr: 2.107 ± 0.125
2.775GlyVal: 2.775 ± 0.128
0.356GlyTrp: 0.356 ± 0.042
1.888GlyTyr: 1.888 ± 0.09
0.0GlyXaa: 0.0 ± 0.0
His
0.79HisAla: 0.79 ± 0.067
0.114HisCys: 0.114 ± 0.021
0.966HisAsp: 0.966 ± 0.063
1.291HisGlu: 1.291 ± 0.069
0.944HisPhe: 0.944 ± 0.073
0.795HisGly: 0.795 ± 0.06
0.501HisHis: 0.501 ± 0.063
1.379HisIle: 1.379 ± 0.081
1.576HisLys: 1.576 ± 0.065
1.927HisLeu: 1.927 ± 0.111
0.259HisMet: 0.259 ± 0.042
1.427HisAsn: 1.427 ± 0.08
0.602HisPro: 0.602 ± 0.047
0.782HisGln: 0.782 ± 0.06
0.47HisArg: 0.47 ± 0.049
0.869HisSer: 0.869 ± 0.079
0.777HisThr: 0.777 ± 0.06
0.918HisVal: 0.918 ± 0.056
0.162HisTrp: 0.162 ± 0.023
0.782HisTyr: 0.782 ± 0.055
0.0HisXaa: 0.0 ± 0.0
Ile
5.444IleAla: 5.444 ± 0.218
0.808IleCys: 0.808 ± 0.078
6.41IleAsp: 6.41 ± 0.182
5.321IleGlu: 5.321 ± 0.19
4.676IlePhe: 4.676 ± 0.222
4.562IleGly: 4.562 ± 0.158
1.427IleHis: 1.427 ± 0.066
10.502IleIle: 10.502 ± 0.334
11.086IleLys: 11.086 ± 0.248
8.992IleLeu: 8.992 ± 0.297
1.642IleMet: 1.642 ± 0.109
11.17IleAsn: 11.17 ± 0.333
2.713IlePro: 2.713 ± 0.14
2.691IleGln: 2.691 ± 0.128
2.634IleArg: 2.634 ± 0.144
7.183IleSer: 7.183 ± 0.187
5.053IleThr: 5.053 ± 0.147
5.774IleVal: 5.774 ± 0.203
0.685IleTrp: 0.685 ± 0.052
4.448IleTyr: 4.448 ± 0.145
0.0IleXaa: 0.0 ± 0.0
Lys
3.956LysAla: 3.956 ± 0.146
0.334LysCys: 0.334 ± 0.043
5.37LysAsp: 5.37 ± 0.154
6.485LysGlu: 6.485 ± 0.243
3.894LysPhe: 3.894 ± 0.142
2.898LysGly: 2.898 ± 0.136
1.822LysHis: 1.822 ± 0.084
11.025LysIle: 11.025 ± 0.279
10.291LysLys: 10.291 ± 0.25
8.785LysLeu: 8.785 ± 0.207
2.112LysMet: 2.112 ± 0.107
10.085LysAsn: 10.085 ± 0.292
2.942LysPro: 2.942 ± 0.177
4.707LysGln: 4.707 ± 0.153
2.986LysArg: 2.986 ± 0.121
5.027LysSer: 5.027 ± 0.174
6.397LysThr: 6.397 ± 0.216
4.961LysVal: 4.961 ± 0.188
0.79LysTrp: 0.79 ± 0.058
4.628LysTyr: 4.628 ± 0.15
0.0LysXaa: 0.0 ± 0.0
Leu
5.326LeuAla: 5.326 ± 0.174
0.663LeuCys: 0.663 ± 0.059
5.809LeuAsp: 5.809 ± 0.167
6.05LeuGlu: 6.05 ± 0.196
4.672LeuPhe: 4.672 ± 0.226
4.083LeuGly: 4.083 ± 0.195
1.414LeuHis: 1.414 ± 0.068
11.332LeuIle: 11.332 ± 0.362
11.029LeuLys: 11.029 ± 0.274
8.939LeuLeu: 8.939 ± 0.313
1.791LeuMet: 1.791 ± 0.09
9.225LeuAsn: 9.225 ± 0.311
2.498LeuPro: 2.498 ± 0.119
2.608LeuGln: 2.608 ± 0.122
2.547LeuArg: 2.547 ± 0.089
6.511LeuSer: 6.511 ± 0.166
5.435LeuThr: 5.435 ± 0.162
5.949LeuVal: 5.949 ± 0.159
0.76LeuTrp: 0.76 ± 0.069
3.394LeuTyr: 3.394 ± 0.127
0.0LeuXaa: 0.0 ± 0.0
Met
0.988MetAla: 0.988 ± 0.072
0.184MetCys: 0.184 ± 0.028
0.852MetAsp: 0.852 ± 0.065
0.584MetGlu: 0.584 ± 0.05
0.861MetPhe: 0.861 ± 0.069
0.799MetGly: 0.799 ± 0.053
0.307MetHis: 0.307 ± 0.041
1.927MetIle: 1.927 ± 0.099
1.563MetLys: 1.563 ± 0.095
1.484MetLeu: 1.484 ± 0.107
0.303MetMet: 0.303 ± 0.037
1.37MetAsn: 1.37 ± 0.092
0.562MetPro: 0.562 ± 0.046
0.795MetGln: 0.795 ± 0.063
0.751MetArg: 0.751 ± 0.061
1.106MetSer: 1.106 ± 0.072
0.72MetThr: 0.72 ± 0.056
0.948MetVal: 0.948 ± 0.073
0.119MetTrp: 0.119 ± 0.023
0.641MetTyr: 0.641 ± 0.064
0.0MetXaa: 0.0 ± 0.0
Asn
3.855AsnAla: 3.855 ± 0.142
0.417AsnCys: 0.417 ± 0.047
6.384AsnAsp: 6.384 ± 0.372
6.063AsnGlu: 6.063 ± 0.206
4.781AsnPhe: 4.781 ± 0.142
3.034AsnGly: 3.034 ± 0.12
1.919AsnHis: 1.919 ± 0.091
7.547AsnIle: 7.547 ± 0.251
10.006AsnLys: 10.006 ± 0.339
9.159AsnLeu: 9.159 ± 0.316
1.234AsnMet: 1.234 ± 0.082
9.615AsnAsn: 9.615 ± 0.649
2.542AsnPro: 2.542 ± 0.092
4.711AsnGln: 4.711 ± 0.226
1.949AsnArg: 1.949 ± 0.112
4.584AsnSer: 4.584 ± 0.183
3.829AsnThr: 3.829 ± 0.227
4.088AsnVal: 4.088 ± 0.224
0.922AsnTrp: 0.922 ± 0.065
4.052AsnTyr: 4.052 ± 0.131
0.0AsnXaa: 0.0 ± 0.0
Pro
1.146ProAla: 1.146 ± 0.191
0.136ProCys: 0.136 ± 0.031
1.045ProAsp: 1.045 ± 0.075
1.357ProGlu: 1.357 ± 0.08
1.344ProPhe: 1.344 ± 0.096
1.133ProGly: 1.133 ± 0.082
0.571ProHis: 0.571 ± 0.059
2.968ProIle: 2.968 ± 0.117
2.56ProLys: 2.56 ± 0.121
2.7ProLeu: 2.7 ± 0.114
0.338ProMet: 0.338 ± 0.038
2.59ProAsn: 2.59 ± 0.172
0.549ProPro: 0.549 ± 0.077
1.251ProGln: 1.251 ± 0.089
0.566ProArg: 0.566 ± 0.048
1.796ProSer: 1.796 ± 0.112
1.686ProThr: 1.686 ± 0.108
1.322ProVal: 1.322 ± 0.087
0.202ProTrp: 0.202 ± 0.029
1.291ProTyr: 1.291 ± 0.064
0.0ProXaa: 0.0 ± 0.0
Gln
1.936GlnAla: 1.936 ± 0.099
0.136GlnCys: 0.136 ± 0.028
1.853GlnAsp: 1.853 ± 0.105
2.226GlnGlu: 2.226 ± 0.081
1.528GlnPhe: 1.528 ± 0.083
1.128GlnGly: 1.128 ± 0.079
0.461GlnHis: 0.461 ± 0.053
4.276GlnIle: 4.276 ± 0.166
4.672GlnLys: 4.672 ± 0.145
3.754GlnLeu: 3.754 ± 0.157
0.689GlnMet: 0.689 ± 0.059
3.508GlnAsn: 3.508 ± 0.154
1.128GlnPro: 1.128 ± 0.206
1.945GlnGln: 1.945 ± 0.11
1.225GlnArg: 1.225 ± 0.071
1.809GlnSer: 1.809 ± 0.084
2.424GlnThr: 2.424 ± 0.131
1.818GlnVal: 1.818 ± 0.093
0.369GlnTrp: 0.369 ± 0.041
1.466GlnTyr: 1.466 ± 0.088
0.0GlnXaa: 0.0 ± 0.0
Arg
1.502ArgAla: 1.502 ± 0.088
0.206ArgCys: 0.206 ± 0.032
1.352ArgAsp: 1.352 ± 0.087
1.682ArgGlu: 1.682 ± 0.096
1.427ArgPhe: 1.427 ± 0.086
1.12ArgGly: 1.12 ± 0.093
0.421ArgHis: 0.421 ± 0.048
2.876ArgIle: 2.876 ± 0.108
2.45ArgLys: 2.45 ± 0.102
2.819ArgLeu: 2.819 ± 0.087
0.641ArgMet: 0.641 ± 0.06
1.976ArgAsn: 1.976 ± 0.105
0.839ArgPro: 0.839 ± 0.064
1.032ArgGln: 1.032 ± 0.077
1.102ArgArg: 1.102 ± 0.082
1.739ArgSer: 1.739 ± 0.116
1.418ArgThr: 1.418 ± 0.079
1.545ArgVal: 1.545 ± 0.105
0.285ArgTrp: 0.285 ± 0.038
1.251ArgTyr: 1.251 ± 0.075
0.0ArgXaa: 0.0 ± 0.0
Ser
2.687SerAla: 2.687 ± 0.106
0.501SerCys: 0.501 ± 0.046
3.043SerAsp: 3.043 ± 0.127
2.705SerGlu: 2.705 ± 0.104
3.802SerPhe: 3.802 ± 0.156
2.845SerGly: 2.845 ± 0.108
0.953SerHis: 0.953 ± 0.066
6.441SerIle: 6.441 ± 0.193
5.269SerLys: 5.269 ± 0.174
6.625SerLeu: 6.625 ± 0.182
1.023SerMet: 1.023 ± 0.074
4.821SerAsn: 4.821 ± 0.288
1.466SerPro: 1.466 ± 0.087
2.116SerGln: 2.116 ± 0.071
1.624SerArg: 1.624 ± 0.092
4.153SerSer: 4.153 ± 0.15
3.218SerThr: 3.218 ± 0.148
3.363SerVal: 3.363 ± 0.125
0.615SerTrp: 0.615 ± 0.048
2.621SerTyr: 2.621 ± 0.123
0.0SerXaa: 0.0 ± 0.0
Thr
2.037ThrAla: 2.037 ± 0.085
0.237ThrCys: 0.237 ± 0.034
1.985ThrAsp: 1.985 ± 0.106
1.725ThrGlu: 1.725 ± 0.097
2.577ThrPhe: 2.577 ± 0.105
2.116ThrGly: 2.116 ± 0.114
0.94ThrHis: 0.94 ± 0.063
5.734ThrIle: 5.734 ± 0.194
5.795ThrLys: 5.795 ± 0.204
5.001ThrLeu: 5.001 ± 0.144
0.641ThrMet: 0.641 ± 0.055
5.049ThrAsn: 5.049 ± 0.287
1.927ThrPro: 1.927 ± 0.099
1.756ThrGln: 1.756 ± 0.113
1.458ThrArg: 1.458 ± 0.1
3.429ThrSer: 3.429 ± 0.131
3.095ThrThr: 3.095 ± 0.14
2.011ThrVal: 2.011 ± 0.106
0.452ThrTrp: 0.452 ± 0.047
2.217ThrTyr: 2.217 ± 0.114
0.0ThrXaa: 0.0 ± 0.0
Val
3.148ValAla: 3.148 ± 0.154
0.58ValCys: 0.58 ± 0.057
3.903ValAsp: 3.903 ± 0.129
2.836ValGlu: 2.836 ± 0.122
2.845ValPhe: 2.845 ± 0.098
2.876ValGly: 2.876 ± 0.145
0.856ValHis: 0.856 ± 0.058
5.506ValIle: 5.506 ± 0.157
4.434ValLys: 4.434 ± 0.183
5.286ValLeu: 5.286 ± 0.157
0.869ValMet: 0.869 ± 0.069
4.672ValAsn: 4.672 ± 0.235
1.229ValPro: 1.229 ± 0.082
1.449ValGln: 1.449 ± 0.083
1.383ValArg: 1.383 ± 0.088
3.372ValSer: 3.372 ± 0.144
1.936ValThr: 1.936 ± 0.106
3.433ValVal: 3.433 ± 0.152
0.562ValTrp: 0.562 ± 0.069
2.428ValTyr: 2.428 ± 0.121
0.0ValXaa: 0.0 ± 0.0
Trp
0.496TrpAla: 0.496 ± 0.057
0.079TrpCys: 0.079 ± 0.015
0.404TrpAsp: 0.404 ± 0.044
0.395TrpGlu: 0.395 ± 0.044
0.602TrpPhe: 0.602 ± 0.059
0.281TrpGly: 0.281 ± 0.033
0.105TrpHis: 0.105 ± 0.022
0.944TrpIle: 0.944 ± 0.075
0.812TrpLys: 0.812 ± 0.058
0.988TrpLeu: 0.988 ± 0.073
0.202TrpMet: 0.202 ± 0.022
0.681TrpAsn: 0.681 ± 0.062
0.193TrpPro: 0.193 ± 0.031
0.246TrpGln: 0.246 ± 0.035
0.246TrpArg: 0.246 ± 0.037
0.522TrpSer: 0.522 ± 0.054
0.465TrpThr: 0.465 ± 0.05
0.461TrpVal: 0.461 ± 0.045
0.127TrpTrp: 0.127 ± 0.026
0.474TrpTyr: 0.474 ± 0.046
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.244TyrAla: 2.244 ± 0.118
0.356TyrCys: 0.356 ± 0.032
3.135TyrAsp: 3.135 ± 0.13
3.381TyrGlu: 3.381 ± 0.118
2.577TyrPhe: 2.577 ± 0.117
1.884TyrGly: 1.884 ± 0.091
0.887TyrHis: 0.887 ± 0.063
3.565TyrIle: 3.565 ± 0.147
3.886TyrLys: 3.886 ± 0.122
5.106TyrLeu: 5.106 ± 0.162
0.606TyrMet: 0.606 ± 0.051
3.13TyrAsn: 3.13 ± 0.124
0.922TyrPro: 0.922 ± 0.06
2.05TyrGln: 2.05 ± 0.098
1.387TyrArg: 1.387 ± 0.08
2.437TyrSer: 2.437 ± 0.092
2.011TyrThr: 2.011 ± 0.1
2.349TyrVal: 2.349 ± 0.105
0.461TyrTrp: 0.461 ± 0.052
2.059TyrTyr: 2.059 ± 0.106
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 611 proteins (227764 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski