Amino acid dipepetide frequency for Teladorsagia circumcincta (Brown stomach worm) (Ostertagia circumcincta)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.01AlaAla: 7.01 ± 0.049	1.287AlaCys: 1.287 ± 0.017	3.921AlaAsp: 3.921 ± 0.029	4.982AlaGlu: 4.982 ± 0.04	2.744AlaPhe: 2.744 ± 0.023	4.402AlaGly: 4.402 ± 0.034	1.674AlaHis: 1.674 ± 0.02	4.053AlaIle: 4.053 ± 0.032	4.336AlaLys: 4.336 ± 0.038	6.604AlaLeu: 6.604 ± 0.037	2.023AlaMet: 2.023 ± 0.019	2.804AlaAsn: 2.804 ± 0.025	3.957AlaPro: 3.957 ± 0.045	2.847AlaGln: 2.847 ± 0.026	4.157AlaArg: 4.157 ± 0.029	5.233AlaSer: 5.233 ± 0.034	4.142AlaThr: 4.142 ± 0.032	5.396AlaVal: 5.396 ± 0.034	0.697AlaTrp: 0.697 ± 0.012	1.979AlaTyr: 1.979 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.416CysAla: 1.416 ± 0.019	0.542CysCys: 0.542 ± 0.012	1.221CysAsp: 1.221 ± 0.02	1.281CysGlu: 1.281 ± 0.017	0.785CysPhe: 0.785 ± 0.012	1.464CysGly: 1.464 ± 0.018	0.513CysHis: 0.513 ± 0.01	1.058CysIle: 1.058 ± 0.013	1.054CysLys: 1.054 ± 0.016	1.657CysLeu: 1.657 ± 0.018	0.488CysMet: 0.488 ± 0.011	0.83CysAsn: 0.83 ± 0.014	1.248CysPro: 1.248 ± 0.02	0.781CysGln: 0.781 ± 0.014	1.223CysArg: 1.223 ± 0.016	1.673CysSer: 1.673 ± 0.021	1.14CysThr: 1.14 ± 0.017	1.349CysVal: 1.349 ± 0.015	0.242CysTrp: 0.242 ± 0.007	0.595CysTyr: 0.595 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.937AspAla: 3.937 ± 0.03	1.138AspCys: 1.138 ± 0.018	4.082AspAsp: 4.082 ± 0.032	4.703AspGlu: 4.703 ± 0.036	2.351AspPhe: 2.351 ± 0.02	3.948AspGly: 3.948 ± 0.036	1.296AspHis: 1.296 ± 0.015	3.005AspIle: 3.005 ± 0.023	2.821AspLys: 2.821 ± 0.023	4.641AspLeu: 4.641 ± 0.033	1.41AspMet: 1.41 ± 0.017	1.972AspAsn: 1.972 ± 0.019	2.636AspPro: 2.636 ± 0.025	1.964AspGln: 1.964 ± 0.02	3.187AspArg: 3.187 ± 0.03	3.822AspSer: 3.822 ± 0.03	2.571AspThr: 2.571 ± 0.021	4.101AspVal: 4.101 ± 0.027	0.721AspTrp: 0.721 ± 0.012	1.863AspTyr: 1.863 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	4.957GluAla: 4.957 ± 0.036	1.242GluCys: 1.242 ± 0.017	3.968GluAsp: 3.968 ± 0.03	6.29GluGlu: 6.29 ± 0.057	2.334GluPhe: 2.334 ± 0.024	3.409GluGly: 3.409 ± 0.027	1.587GluHis: 1.587 ± 0.02	3.512GluIle: 3.512 ± 0.029	5.248GluLys: 5.248 ± 0.044	5.794GluLeu: 5.794 ± 0.042	2.047GluMet: 2.047 ± 0.022	3.009GluAsn: 3.009 ± 0.027	2.686GluPro: 2.686 ± 0.029	2.926GluGln: 2.926 ± 0.025	4.464GluArg: 4.464 ± 0.039	4.196GluSer: 4.196 ± 0.035	3.373GluThr: 3.373 ± 0.029	4.119GluVal: 4.119 ± 0.031	0.852GluTrp: 0.852 ± 0.012	1.97GluTyr: 1.97 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.965PheAla: 2.965 ± 0.027	0.947PheCys: 0.947 ± 0.015	2.471PheAsp: 2.471 ± 0.022	2.391PheGlu: 2.391 ± 0.023	1.726PhePhe: 1.726 ± 0.019	2.737PheGly: 2.737 ± 0.025	1.009PheHis: 1.009 ± 0.013	2.144PheIle: 2.144 ± 0.023	1.883PheLys: 1.883 ± 0.022	3.434PheLeu: 3.434 ± 0.025	0.97PheMet: 0.97 ± 0.015	1.612PheAsn: 1.612 ± 0.016	1.771PhePro: 1.771 ± 0.022	1.306PheGln: 1.306 ± 0.015	2.171PheArg: 2.171 ± 0.021	2.85PheSer: 2.85 ± 0.024	2.251PheThr: 2.251 ± 0.02	2.872PheVal: 2.872 ± 0.024	0.483PheTrp: 0.483 ± 0.009	1.374PheTyr: 1.374 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.328GlyAla: 4.328 ± 0.036	1.439GlyCys: 1.439 ± 0.018	3.353GlyAsp: 3.353 ± 0.027	3.813GlyGlu: 3.813 ± 0.034	2.572GlyPhe: 2.572 ± 0.022	4.866GlyGly: 4.866 ± 0.06	1.483GlyHis: 1.483 ± 0.019	3.092GlyIle: 3.092 ± 0.027	3.548GlyLys: 3.548 ± 0.031	4.625GlyLeu: 4.625 ± 0.041	1.69GlyMet: 1.69 ± 0.023	2.48GlyAsn: 2.48 ± 0.022	3.077GlyPro: 3.077 ± 0.057	2.382GlyGln: 2.382 ± 0.028	3.736GlyArg: 3.736 ± 0.033	4.51GlySer: 4.51 ± 0.038	3.399GlyThr: 3.399 ± 0.029	4.148GlyVal: 4.148 ± 0.031	0.76GlyTrp: 0.76 ± 0.013	2.195GlyTyr: 2.195 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	1.561HisAla: 1.561 ± 0.016	0.57HisCys: 0.57 ± 0.012	1.249HisAsp: 1.249 ± 0.016	1.476HisGlu: 1.476 ± 0.017	1.006HisPhe: 1.006 ± 0.013	1.568HisGly: 1.568 ± 0.022	0.796HisHis: 0.796 ± 0.013	1.206HisIle: 1.206 ± 0.016	1.153HisLys: 1.153 ± 0.016	2.146HisLeu: 2.146 ± 0.018	0.645HisMet: 0.645 ± 0.011	0.989HisAsn: 0.989 ± 0.013	1.332HisPro: 1.332 ± 0.017	0.908HisGln: 0.908 ± 0.013	1.594HisArg: 1.594 ± 0.018	1.744HisSer: 1.744 ± 0.018	1.155HisThr: 1.155 ± 0.014	1.597HisVal: 1.597 ± 0.019	0.316HisTrp: 0.316 ± 0.008	0.917HisTyr: 0.917 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.133IleAla: 4.133 ± 0.028	1.185IleCys: 1.185 ± 0.015	3.227IleAsp: 3.227 ± 0.028	3.5IleGlu: 3.5 ± 0.03	2.093IlePhe: 2.093 ± 0.018	3.274IleGly: 3.274 ± 0.028	1.269IleHis: 1.269 ± 0.016	2.693IleIle: 2.693 ± 0.023	2.631IleLys: 2.631 ± 0.024	4.382IleLeu: 4.382 ± 0.031	1.282IleMet: 1.282 ± 0.017	2.059IleAsn: 2.059 ± 0.02	2.726IlePro: 2.726 ± 0.024	1.835IleGln: 1.835 ± 0.018	3.335IleArg: 3.335 ± 0.027	3.782IleSer: 3.782 ± 0.028	3.006IleThr: 3.006 ± 0.024	3.659IleVal: 3.659 ± 0.028	0.567IleTrp: 0.567 ± 0.01	1.637IleTyr: 1.637 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.208LysAla: 4.208 ± 0.036	1.174LysCys: 1.174 ± 0.018	3.189LysAsp: 3.189 ± 0.027	4.657LysGlu: 4.657 ± 0.044	1.995LysPhe: 1.995 ± 0.021	3.088LysGly: 3.088 ± 0.032	1.316LysHis: 1.316 ± 0.019	3.095LysIle: 3.095 ± 0.026	4.894LysLys: 4.894 ± 0.048	4.898LysLeu: 4.898 ± 0.039	1.821LysMet: 1.821 ± 0.021	2.46LysAsn: 2.46 ± 0.021	2.719LysPro: 2.719 ± 0.031	2.266LysGln: 2.266 ± 0.022	3.915LysArg: 3.915 ± 0.028	3.774LysSer: 3.774 ± 0.032	3.194LysThr: 3.194 ± 0.026	3.638LysVal: 3.638 ± 0.029	0.75LysTrp: 0.75 ± 0.011	1.827LysTyr: 1.827 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	6.501LeuAla: 6.501 ± 0.043	1.824LeuCys: 1.824 ± 0.018	4.693LeuAsp: 4.693 ± 0.033	5.611LeuGlu: 5.611 ± 0.045	3.547LeuPhe: 3.547 ± 0.026	4.573LeuGly: 4.573 ± 0.029	2.195LeuHis: 2.195 ± 0.018	4.421LeuIle: 4.421 ± 0.032	5.09LeuLys: 5.09 ± 0.035	8.205LeuLeu: 8.205 ± 0.049	2.307LeuMet: 2.307 ± 0.021	3.55LeuAsn: 3.55 ± 0.029	4.593LeuPro: 4.593 ± 0.039	3.492LeuGln: 3.492 ± 0.031	5.65LeuArg: 5.65 ± 0.032	6.474LeuSer: 6.474 ± 0.036	4.677LeuThr: 4.677 ± 0.03	5.368LeuVal: 5.368 ± 0.034	0.994LeuTrp: 0.994 ± 0.015	2.456LeuTyr: 2.456 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.11MetAla: 2.11 ± 0.02	0.494MetCys: 0.494 ± 0.009	1.505MetAsp: 1.505 ± 0.017	1.93MetGlu: 1.93 ± 0.02	1.1MetPhe: 1.1 ± 0.016	1.539MetGly: 1.539 ± 0.019	0.617MetHis: 0.617 ± 0.011	1.363MetIle: 1.363 ± 0.017	1.763MetLys: 1.763 ± 0.021	2.418MetLeu: 2.418 ± 0.02	0.874MetMet: 0.874 ± 0.014	1.172MetAsn: 1.172 ± 0.015	1.366MetPro: 1.366 ± 0.019	1.034MetGln: 1.034 ± 0.015	1.642MetArg: 1.642 ± 0.022	1.967MetSer: 1.967 ± 0.017	1.567MetThr: 1.567 ± 0.016	1.726MetVal: 1.726 ± 0.019	0.298MetTrp: 0.298 ± 0.008	0.78MetTyr: 0.78 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.936AsnAla: 2.936 ± 0.026	0.858AsnCys: 0.858 ± 0.014	2.25AsnAsp: 2.25 ± 0.022	2.768AsnGlu: 2.768 ± 0.025	1.648AsnPhe: 1.648 ± 0.02	3.081AsnGly: 3.081 ± 0.025	0.889AsnHis: 0.889 ± 0.012	2.207AsnIle: 2.207 ± 0.021	2.086AsnLys: 2.086 ± 0.022	3.261AsnLeu: 3.261 ± 0.026	1.118AsnMet: 1.118 ± 0.015	1.686AsnAsn: 1.686 ± 0.02	2.135AsnPro: 2.135 ± 0.021	1.403AsnGln: 1.403 ± 0.016	2.334AsnArg: 2.334 ± 0.019	2.703AsnSer: 2.703 ± 0.024	2.097AsnThr: 2.097 ± 0.018	2.85AsnVal: 2.85 ± 0.023	0.467AsnTrp: 0.467 ± 0.009	1.432AsnTyr: 1.432 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	3.737ProAla: 3.737 ± 0.04	0.868ProCys: 0.868 ± 0.015	2.673ProAsp: 2.673 ± 0.022	3.261ProGlu: 3.261 ± 0.029	1.907ProPhe: 1.907 ± 0.019	3.996ProGly: 3.996 ± 0.105	1.135ProHis: 1.135 ± 0.016	2.495ProIle: 2.495 ± 0.023	2.824ProLys: 2.824 ± 0.028	4.036ProLeu: 4.036 ± 0.034	1.231ProMet: 1.231 ± 0.017	1.982ProAsn: 1.982 ± 0.021	4.754ProPro: 4.754 ± 0.073	2.088ProGln: 2.088 ± 0.03	2.756ProArg: 2.756 ± 0.025	4.517ProSer: 4.517 ± 0.04	3.135ProThr: 3.135 ± 0.033	3.405ProVal: 3.405 ± 0.031	0.503ProTrp: 0.503 ± 0.01	1.533ProTyr: 1.533 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	2.685GlnAla: 2.685 ± 0.026	0.859GlnCys: 0.859 ± 0.017	1.557GlnAsp: 1.557 ± 0.018	2.364GlnGlu: 2.364 ± 0.022	1.591GlnPhe: 1.591 ± 0.015	1.863GlnGly: 1.863 ± 0.025	0.946GlnHis: 0.946 ± 0.014	2.059GlnIle: 2.059 ± 0.02	2.44GlnLys: 2.44 ± 0.024	4.015GlnLeu: 4.015 ± 0.031	1.305GlnMet: 1.305 ± 0.017	1.557GlnAsn: 1.557 ± 0.02	2.16GlnPro: 2.16 ± 0.03	2.217GlnGln: 2.217 ± 0.036	2.529GlnArg: 2.529 ± 0.022	2.529GlnSer: 2.529 ± 0.025	1.955GlnThr: 1.955 ± 0.021	2.3GlnVal: 2.3 ± 0.019	0.512GlnTrp: 0.512 ± 0.01	1.244GlnTyr: 1.244 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.039ArgAla: 4.039 ± 0.028	1.207ArgCys: 1.207 ± 0.017	3.181ArgAsp: 3.181 ± 0.028	4.006ArgGlu: 4.006 ± 0.032	2.461ArgPhe: 2.461 ± 0.022	3.219ArgGly: 3.219 ± 0.033	1.561ArgHis: 1.561 ± 0.017	3.255ArgIle: 3.255 ± 0.027	4.072ArgLys: 4.072 ± 0.033	5.577ArgLeu: 5.577 ± 0.032	1.741ArgMet: 1.741 ± 0.016	2.586ArgAsn: 2.586 ± 0.021	2.964ArgPro: 2.964 ± 0.025	2.579ArgGln: 2.579 ± 0.022	5.011ArgArg: 5.011 ± 0.043	4.372ArgSer: 4.372 ± 0.035	3.218ArgThr: 3.218 ± 0.031	3.69ArgVal: 3.69 ± 0.029	0.732ArgTrp: 0.732 ± 0.012	1.832ArgTyr: 1.832 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	5.333SerAla: 5.333 ± 0.037	1.434SerCys: 1.434 ± 0.018	4.087SerAsp: 4.087 ± 0.033	4.471SerGlu: 4.471 ± 0.034	2.844SerPhe: 2.844 ± 0.023	4.565SerGly: 4.565 ± 0.034	1.69SerHis: 1.69 ± 0.018	3.651SerIle: 3.651 ± 0.027	3.949SerLys: 3.949 ± 0.033	6.185SerLeu: 6.185 ± 0.036	1.875SerMet: 1.875 ± 0.019	2.717SerAsn: 2.717 ± 0.021	3.931SerPro: 3.931 ± 0.039	2.649SerGln: 2.649 ± 0.026	4.33SerArg: 4.33 ± 0.033	7.186SerSer: 7.186 ± 0.068	4.732SerThr: 4.732 ± 0.04	4.756SerVal: 4.756 ± 0.035	0.778SerTrp: 0.778 ± 0.012	2.044SerTyr: 2.044 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	4.418ThrAla: 4.418 ± 0.03	1.148ThrCys: 1.148 ± 0.019	2.873ThrAsp: 2.873 ± 0.022	3.328ThrGlu: 3.328 ± 0.029	2.109ThrPhe: 2.109 ± 0.019	3.322ThrGly: 3.322 ± 0.03	1.23ThrHis: 1.23 ± 0.015	3.123ThrIle: 3.123 ± 0.028	2.979ThrLys: 2.979 ± 0.024	4.786ThrLeu: 4.786 ± 0.033	1.46ThrMet: 1.46 ± 0.019	2.126ThrAsn: 2.126 ± 0.021	3.336ThrPro: 3.336 ± 0.032	1.898ThrGln: 1.898 ± 0.018	2.833ThrArg: 2.833 ± 0.024	4.394ThrSer: 4.394 ± 0.041	4.129ThrThr: 4.129 ± 0.061	4.208ThrVal: 4.208 ± 0.03	0.607ThrTrp: 0.607 ± 0.012	1.599ThrTyr: 1.599 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.075ValAla: 5.075 ± 0.034	1.364ValCys: 1.364 ± 0.017	4.148ValAsp: 4.148 ± 0.027	4.563ValGlu: 4.563 ± 0.03	2.814ValPhe: 2.814 ± 0.024	3.66ValGly: 3.66 ± 0.028	1.649ValHis: 1.649 ± 0.016	3.64ValIle: 3.64 ± 0.029	3.756ValLys: 3.756 ± 0.03	5.909ValLeu: 5.909 ± 0.035	1.748ValMet: 1.748 ± 0.019	2.697ValAsn: 2.697 ± 0.025	3.514ValPro: 3.514 ± 0.031	2.478ValGln: 2.478 ± 0.025	3.772ValArg: 3.772 ± 0.028	4.538ValSer: 4.538 ± 0.031	3.781ValThr: 3.781 ± 0.033	5.194ValVal: 5.194 ± 0.037	0.721ValTrp: 0.721 ± 0.013	1.981ValTyr: 1.981 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.769TrpAla: 0.769 ± 0.012	0.22TrpCys: 0.22 ± 0.007	0.61TrpAsp: 0.61 ± 0.01	0.66TrpGlu: 0.66 ± 0.01	0.472TrpPhe: 0.472 ± 0.01	0.601TrpGly: 0.601 ± 0.013	0.287TrpHis: 0.287 ± 0.009	0.733TrpIle: 0.733 ± 0.013	0.758TrpLys: 0.758 ± 0.012	1.03TrpLeu: 1.03 ± 0.016	0.412TrpMet: 0.412 ± 0.009	0.532TrpAsn: 0.532 ± 0.011	0.496TrpPro: 0.496 ± 0.01	0.509TrpGln: 0.509 ± 0.011	0.72TrpArg: 0.72 ± 0.013	0.849TrpSer: 0.849 ± 0.014	0.759TrpThr: 0.759 ± 0.012	0.641TrpVal: 0.641 ± 0.01	0.18TrpTrp: 0.18 ± 0.006	0.377TrpTyr: 0.377 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.127TyrAla: 2.127 ± 0.02	0.763TyrCys: 0.763 ± 0.013	1.911TyrAsp: 1.911 ± 0.021	1.928TyrGlu: 1.928 ± 0.019	1.268TyrPhe: 1.268 ± 0.016	2.32TyrGly: 2.32 ± 0.029	0.787TyrHis: 0.787 ± 0.013	1.469TyrIle: 1.469 ± 0.017	1.594TyrLys: 1.594 ± 0.019	2.622TyrLeu: 2.622 ± 0.024	0.819TyrMet: 0.819 ± 0.013	1.386TyrAsn: 1.386 ± 0.017	1.436TyrPro: 1.436 ± 0.018	1.122TyrGln: 1.122 ± 0.015	1.944TyrArg: 1.944 ± 0.019	2.093TyrSer: 2.093 ± 0.024	1.627TyrThr: 1.627 ± 0.019	1.984TyrVal: 1.984 ± 0.019	0.436TyrTrp: 0.436 ± 0.009	1.21TyrTyr: 1.21 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 25373 proteins (5444164 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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