Tolypocladium cylindrosporum virus 1

Taxonomy: Viruses; Riboviria; Orthornavirae; Duplornaviricota; Chrymotiviricetes; Ghabrivirales; Totiviridae; Victorivirus

Average proteome isoelectric point is 6.96

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|E7BBP7|E7BBP7_9VIRU RNA-directed RNA polymerase OS=Tolypocladium cylindrosporum virus 1 OX=939923 GN=RdRp PE=3 SV=1
MM1 pKa = 7.86DD2 pKa = 5.02FIIRR6 pKa = 11.84NSFLSGVIASPRR18 pKa = 11.84GGSLDD23 pKa = 3.1NDD25 pKa = 3.12NRR27 pKa = 11.84FRR29 pKa = 11.84RR30 pKa = 11.84YY31 pKa = 7.37RR32 pKa = 11.84TSVRR36 pKa = 11.84TTATIGGNDD45 pKa = 3.86DD46 pKa = 3.68SRR48 pKa = 11.84TTSIFYY54 pKa = 10.38EE55 pKa = 4.05VGRR58 pKa = 11.84AVNTKK63 pKa = 9.25GRR65 pKa = 11.84ALNRR69 pKa = 11.84PSDD72 pKa = 3.56GALCIEE78 pKa = 4.64AAYY81 pKa = 7.13PTNTVLAEE89 pKa = 4.09DD90 pKa = 5.26FIGLAKK96 pKa = 10.54KK97 pKa = 8.47YY98 pKa = 8.69TNFSASFEE106 pKa = 4.23YY107 pKa = 10.81SSLAGVAEE115 pKa = 4.06RR116 pKa = 11.84LARR119 pKa = 11.84ALAASSVFTDD129 pKa = 3.16VDD131 pKa = 4.2SNDD134 pKa = 2.92IRR136 pKa = 11.84GGAGLVVNAVGTYY149 pKa = 9.9DD150 pKa = 4.05GPISSLTNTVYY161 pKa = 10.38IPRR164 pKa = 11.84LVNSSITGEE173 pKa = 4.26VFSVLANAVSGEE185 pKa = 4.15GSSVATDD192 pKa = 4.25IIEE195 pKa = 4.41LDD197 pKa = 3.31AGTRR201 pKa = 11.84QPLIPEE207 pKa = 4.07VDD209 pKa = 3.63PAGLAAACVDD219 pKa = 3.5ALRR222 pKa = 11.84IVGSNMIASDD232 pKa = 3.62QGPLFSLAVTRR243 pKa = 11.84GIHH246 pKa = 5.82RR247 pKa = 11.84VLSVVGHH254 pKa = 5.45TDD256 pKa = 2.62EE257 pKa = 5.93GGITRR262 pKa = 11.84DD263 pKa = 3.64LLRR266 pKa = 11.84CSSFAPPFGGIHH278 pKa = 6.0YY279 pKa = 10.37ALEE282 pKa = 4.83PYY284 pKa = 10.56AGLPALQFTAFPAYY298 pKa = 9.82AAYY301 pKa = 10.32VDD303 pKa = 5.23SIALTTAAVVAHH315 pKa = 7.19ADD317 pKa = 3.45PGVMYY322 pKa = 10.42GGSWFPTFYY331 pKa = 11.02NGTADD336 pKa = 2.9SDD338 pKa = 4.01GTVRR342 pKa = 11.84PGQNQAGTAAMANRR356 pKa = 11.84NRR358 pKa = 11.84AQLLGSAPAFFSEE371 pKa = 4.6YY372 pKa = 10.01IRR374 pKa = 11.84GLATIFGASGDD385 pKa = 3.63SSLACRR391 pKa = 11.84FMGAASYY398 pKa = 10.82ALPQDD403 pKa = 3.91PRR405 pKa = 11.84HH406 pKa = 5.75LRR408 pKa = 11.84YY409 pKa = 8.93ATVSPWFWIEE419 pKa = 3.69PTGLLPHH426 pKa = 7.31DD427 pKa = 4.03FLGSKK432 pKa = 10.63AEE434 pKa = 4.11ANGAGSFAWKK444 pKa = 8.74DD445 pKa = 3.4TTRR448 pKa = 11.84TRR450 pKa = 11.84VAWDD454 pKa = 3.53EE455 pKa = 4.01LTQHH459 pKa = 6.61GEE461 pKa = 3.64ADD463 pKa = 3.95TTFSAYY469 pKa = 8.54VARR472 pKa = 11.84FRR474 pKa = 11.84SPRR477 pKa = 11.84QQWFFAHH484 pKa = 6.75WMNHH488 pKa = 4.98PLNGLGAIRR497 pKa = 11.84VRR499 pKa = 11.84QLDD502 pKa = 3.58PNGIVQPGQCVAHH515 pKa = 7.03PDD517 pKa = 3.13VRR519 pKa = 11.84DD520 pKa = 3.42RR521 pKa = 11.84VEE523 pKa = 4.61ADD525 pKa = 4.14LPFTDD530 pKa = 4.54YY531 pKa = 11.29LWTRR535 pKa = 11.84GQSPPPAPGEE545 pKa = 3.87LLNLSGSVGFLVRR558 pKa = 11.84HH559 pKa = 5.7LTYY562 pKa = 11.09DD563 pKa = 3.76DD564 pKa = 5.25DD565 pKa = 4.58GVPHH569 pKa = 6.99EE570 pKa = 4.37EE571 pKa = 4.0HH572 pKa = 6.37VPTRR576 pKa = 11.84RR577 pKa = 11.84EE578 pKa = 3.94FLDD581 pKa = 3.35TTVTIEE587 pKa = 3.5VGRR590 pKa = 11.84PVGIATGASNAGDD603 pKa = 3.29NHH605 pKa = 5.37VRR607 pKa = 11.84RR608 pKa = 11.84ARR610 pKa = 11.84TKK612 pKa = 10.34AANEE616 pKa = 3.42LAAARR621 pKa = 11.84RR622 pKa = 11.84RR623 pKa = 11.84AAVFGRR629 pKa = 11.84ADD631 pKa = 3.47VAEE634 pKa = 4.15MPILTSAPALAPPPSAGLEE653 pKa = 3.97RR654 pKa = 11.84GSDD657 pKa = 3.54PGGSGSQRR665 pKa = 11.84RR666 pKa = 11.84AVPAGLPGNDD676 pKa = 2.51TWARR680 pKa = 11.84EE681 pKa = 4.11PTGAPRR687 pKa = 11.84NPVPHH692 pKa = 6.4HH693 pKa = 5.9QPLRR697 pKa = 11.84APQLARR703 pKa = 11.84QAGGLGGGAAPIPPPPPGVPAPPALPPADD732 pKa = 5.29DD733 pKa = 5.48DD734 pKa = 4.3NAPPAPVATAPPVADD749 pKa = 3.92PQAMVGDD756 pKa = 4.23QII758 pKa = 4.63

Molecular weight:
79.87 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|E7BBP7|E7BBP7_9VIRU RNA-directed RNA polymerase OS=Tolypocladium cylindrosporum virus 1 OX=939923 GN=RdRp PE=3 SV=1
MM1 pKa = 7.13VFVSGRR7 pKa = 11.84VGEE10 pKa = 4.65FGALGSYY17 pKa = 10.26LHH19 pKa = 7.35DD20 pKa = 5.03LLPEE24 pKa = 4.86LGDD27 pKa = 3.62VTEE30 pKa = 5.08SYY32 pKa = 11.86ADD34 pKa = 3.84LEE36 pKa = 4.35LTEE39 pKa = 4.14QLIKK43 pKa = 10.5FATHH47 pKa = 5.6SVSLRR52 pKa = 11.84GVHH55 pKa = 6.25PLGPVAVSLLCVAYY69 pKa = 9.08PVQCDD74 pKa = 3.76FRR76 pKa = 11.84LSDD79 pKa = 3.54LTAVLRR85 pKa = 11.84HH86 pKa = 5.78SFSFLPQRR94 pKa = 11.84APLLEE99 pKa = 3.99LTGLIEE105 pKa = 4.77RR106 pKa = 11.84RR107 pKa = 11.84VTLRR111 pKa = 11.84KK112 pKa = 9.91APATIGALHH121 pKa = 6.17TKK123 pKa = 8.48VARR126 pKa = 11.84LCNSDD131 pKa = 3.11SAARR135 pKa = 11.84SQLWPPKK142 pKa = 8.94RR143 pKa = 11.84HH144 pKa = 5.7AAAGTKK150 pKa = 10.25VNIRR154 pKa = 11.84LAPLAVALSRR164 pKa = 11.84SYY166 pKa = 11.34GPAWLGRR173 pKa = 11.84ALTPLVGCAEE183 pKa = 4.38DD184 pKa = 4.45AVCCALLLATALEE197 pKa = 4.21PHH199 pKa = 6.84FGHH202 pKa = 7.42LGLEE206 pKa = 4.79VAQSMILEE214 pKa = 4.35PNNAKK219 pKa = 10.3GLSNALKK226 pKa = 10.41ALGWNSTLPGSMLVEE241 pKa = 4.83GGALQGRR248 pKa = 11.84GVSPVDD254 pKa = 3.32MDD256 pKa = 4.52AEE258 pKa = 4.38IASRR262 pKa = 11.84TTPDD266 pKa = 3.62LVTDD270 pKa = 3.93MVISSAAEE278 pKa = 3.71MAPHH282 pKa = 6.39IRR284 pKa = 11.84AILALEE290 pKa = 4.45LPSNSGLGDD299 pKa = 3.8LDD301 pKa = 4.28EE302 pKa = 4.9FWSARR307 pKa = 11.84WLWCVNGAQNRR318 pKa = 11.84ASDD321 pKa = 3.61RR322 pKa = 11.84SLNLPSPVRR331 pKa = 11.84GAKK334 pKa = 9.93RR335 pKa = 11.84YY336 pKa = 9.53RR337 pKa = 11.84RR338 pKa = 11.84MAAEE342 pKa = 4.27EE343 pKa = 4.26VSSNPIYY350 pKa = 10.97DD351 pKa = 3.31WDD353 pKa = 3.64GTTNVSASTKK363 pKa = 10.34LEE365 pKa = 4.31PGKK368 pKa = 10.73SRR370 pKa = 11.84AIFACDD376 pKa = 3.03TSSYY380 pKa = 10.84FAFSWILDD388 pKa = 3.42RR389 pKa = 11.84AQRR392 pKa = 11.84DD393 pKa = 3.59WRR395 pKa = 11.84GHH397 pKa = 5.46RR398 pKa = 11.84VLLNPGEE405 pKa = 4.34GGLYY409 pKa = 10.07GVARR413 pKa = 11.84RR414 pKa = 11.84VKK416 pKa = 9.26GAQGRR421 pKa = 11.84GGVNVMLDD429 pKa = 3.4YY430 pKa = 11.58DD431 pKa = 4.74DD432 pKa = 5.89FNSHH436 pKa = 6.63HH437 pKa = 6.74SLGVQQEE444 pKa = 4.29LTRR447 pKa = 11.84QLCQLYY453 pKa = 9.8NAPSWYY459 pKa = 9.58TSVLVDD465 pKa = 3.8SFDD468 pKa = 3.58RR469 pKa = 11.84MYY471 pKa = 9.63ITHH474 pKa = 6.89RR475 pKa = 11.84GSRR478 pKa = 11.84KK479 pKa = 9.8RR480 pKa = 11.84ILGTLMSGHH489 pKa = 7.14RR490 pKa = 11.84GTSFINSVLNAAYY503 pKa = 9.38IRR505 pKa = 11.84AAVGGAFFDD514 pKa = 3.99RR515 pKa = 11.84LVSLHH520 pKa = 6.86AGDD523 pKa = 4.51DD524 pKa = 3.41AYY526 pKa = 10.81MRR528 pKa = 11.84CSTLAEE534 pKa = 4.16AAHH537 pKa = 5.82VLTRR541 pKa = 11.84CARR544 pKa = 11.84FGCRR548 pKa = 11.84MNPTKK553 pKa = 10.53QSIGFRR559 pKa = 11.84HH560 pKa = 6.48AEE562 pKa = 3.93FLRR565 pKa = 11.84LGIGDD570 pKa = 4.47KK571 pKa = 11.0YY572 pKa = 11.29AVGYY576 pKa = 9.11LCRR579 pKa = 11.84SISTLVAGSWVAPDD593 pKa = 4.15PLSPEE598 pKa = 4.88DD599 pKa = 4.28GLTSAITTVRR609 pKa = 11.84SCINRR614 pKa = 11.84GCPSSLSRR622 pKa = 11.84IIARR626 pKa = 11.84TYY628 pKa = 11.11SSIHH632 pKa = 6.34GYY634 pKa = 7.9PLRR637 pKa = 11.84VLDD640 pKa = 4.69ALLSGAACLEE650 pKa = 4.13SGAVYY655 pKa = 8.76NTDD658 pKa = 3.01YY659 pKa = 10.89TLRR662 pKa = 11.84QYY664 pKa = 10.98RR665 pKa = 11.84VVRR668 pKa = 11.84PLPDD672 pKa = 4.84DD673 pKa = 4.61LPLPPQHH680 pKa = 6.92RR681 pKa = 11.84EE682 pKa = 3.68YY683 pKa = 10.67ATRR686 pKa = 11.84EE687 pKa = 3.69YY688 pKa = 10.59LANHH692 pKa = 6.09VSPIEE697 pKa = 3.87ARR699 pKa = 11.84AAQLASADD707 pKa = 3.86LVRR710 pKa = 11.84IMVRR714 pKa = 11.84SSYY717 pKa = 10.95SKK719 pKa = 10.28GVTRR723 pKa = 11.84HH724 pKa = 5.92PSSPTSRR731 pKa = 11.84RR732 pKa = 11.84RR733 pKa = 11.84PQLVSLPTVKK743 pKa = 10.03ATGFTTAAEE752 pKa = 4.07LAKK755 pKa = 10.26RR756 pKa = 11.84QPPVGKK762 pKa = 9.69LANFPLLRR770 pKa = 11.84LIEE773 pKa = 4.24ARR775 pKa = 11.84LTDD778 pKa = 3.86DD779 pKa = 4.67QISEE783 pKa = 4.35LLSFNGTPPGGLPPRR798 pKa = 11.84IAAFGVEE805 pKa = 4.12GHH807 pKa = 6.53CCNVIGYY814 pKa = 9.1LPYY817 pKa = 10.71SDD819 pKa = 3.98ACSYY823 pKa = 11.09SKK825 pKa = 10.13RR826 pKa = 11.84TTCDD830 pKa = 3.09NIIAGYY836 pKa = 9.3SVYY839 pKa = 11.07SS840 pKa = 3.59

Molecular weight:
91.21 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

1598

758

840

799.0

85.54

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

12.203 ± 1.088

1.564 ± 0.597

5.319 ± 0.494

3.63 ± 0.132

3.379 ± 0.469

8.824 ± 0.706

2.378 ± 0.176

3.88 ± 0.051

1.564 ± 0.51

9.825 ± 1.607

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.314 ± 0.171

3.442 ± 0.253

7.259 ± 1.042

2.503 ± 0.089

7.822 ± 0.286

8.073 ± 0.8

5.882 ± 0.384

6.884 ± 0.072

1.252 ± 0.042

3.004 ± 0.328

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski