Amino acid dipepetide frequency for Palma virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.391AlaAla: 5.391 ± 3.547
1.887AlaCys: 1.887 ± 0.564
2.695AlaAsp: 2.695 ± 0.342
2.426AlaGlu: 2.426 ± 0.582
2.426AlaPhe: 2.426 ± 1.306
2.156AlaGly: 2.156 ± 0.74
0.0AlaHis: 0.0 ± 0.0
3.504AlaIle: 3.504 ± 0.85
4.043AlaLys: 4.043 ± 1.361
7.008AlaLeu: 7.008 ± 2.628
1.078AlaMet: 1.078 ± 1.468
2.156AlaAsn: 2.156 ± 0.962
2.156AlaPro: 2.156 ± 0.498
2.156AlaGln: 2.156 ± 0.387
3.774AlaArg: 3.774 ± 0.798
5.391AlaSer: 5.391 ± 0.251
3.235AlaThr: 3.235 ± 1.044
3.504AlaVal: 3.504 ± 0.811
1.078AlaTrp: 1.078 ± 0.4
1.617AlaTyr: 1.617 ± 0.964
0.0AlaXaa: 0.0 ± 0.0
Cys
2.156CysAla: 2.156 ± 0.904
0.809CysCys: 0.809 ± 0.453
1.348CysAsp: 1.348 ± 0.765
1.348CysGlu: 1.348 ± 0.391
1.078CysPhe: 1.078 ± 0.37
1.887CysGly: 1.887 ± 1.084
0.27CysHis: 0.27 ± 0.164
2.156CysIle: 2.156 ± 1.007
2.426CysLys: 2.426 ± 0.743
3.235CysLeu: 3.235 ± 0.953
1.617CysMet: 1.617 ± 0.664
0.0CysAsn: 0.0 ± 0.0
0.539CysPro: 0.539 ± 0.547
0.539CysGln: 0.539 ± 0.185
1.617CysArg: 1.617 ± 0.555
3.774CysSer: 3.774 ± 2.168
1.887CysThr: 1.887 ± 1.199
1.348CysVal: 1.348 ± 0.592
0.0CysTrp: 0.0 ± 0.0
0.809CysTyr: 0.809 ± 0.742
0.0CysXaa: 0.0 ± 0.0
Asp
2.426AspAla: 2.426 ± 0.794
1.617AspCys: 1.617 ± 0.555
4.582AspAsp: 4.582 ± 0.991
6.739AspGlu: 6.739 ± 0.599
2.695AspPhe: 2.695 ± 0.782
4.313AspGly: 4.313 ± 0.758
0.809AspHis: 0.809 ± 0.236
4.043AspIle: 4.043 ± 1.681
1.887AspLys: 1.887 ± 0.839
4.313AspLeu: 4.313 ± 1.187
1.617AspMet: 1.617 ± 0.835
2.156AspAsn: 2.156 ± 0.498
2.156AspPro: 2.156 ± 0.717
1.078AspGln: 1.078 ± 0.361
2.695AspArg: 2.695 ± 0.356
4.043AspSer: 4.043 ± 1.399
3.504AspThr: 3.504 ± 1.227
3.235AspVal: 3.235 ± 0.685
0.539AspTrp: 0.539 ± 0.547
1.617AspTyr: 1.617 ± 0.664
0.0AspXaa: 0.0 ± 0.0
Glu
4.043GluAla: 4.043 ± 1.331
1.348GluCys: 1.348 ± 0.391
5.391GluAsp: 5.391 ± 1.65
6.199GluGlu: 6.199 ± 1.845
2.426GluPhe: 2.426 ± 0.331
4.852GluGly: 4.852 ± 1.154
0.809GluHis: 0.809 ± 0.236
2.426GluIle: 2.426 ± 0.858
3.774GluLys: 3.774 ± 1.175
7.817GluLeu: 7.817 ± 0.364
1.887GluMet: 1.887 ± 0.583
2.695GluAsn: 2.695 ± 1.012
1.078GluPro: 1.078 ± 0.361
2.695GluGln: 2.695 ± 0.709
4.043GluArg: 4.043 ± 1.129
6.469GluSer: 6.469 ± 1.551
3.504GluThr: 3.504 ± 1.879
7.008GluVal: 7.008 ± 0.899
0.27GluTrp: 0.27 ± 0.164
1.348GluTyr: 1.348 ± 0.627
0.0GluXaa: 0.0 ± 0.0
Phe
4.313PheAla: 4.313 ± 1.196
2.156PheCys: 2.156 ± 1.059
1.887PheAsp: 1.887 ± 1.856
1.617PheGlu: 1.617 ± 0.48
2.156PhePhe: 2.156 ± 0.619
2.156PheGly: 2.156 ± 0.717
0.809PheHis: 0.809 ± 0.417
2.426PheIle: 2.426 ± 0.953
3.774PheLys: 3.774 ± 1.375
4.852PheLeu: 4.852 ± 1.688
1.078PheMet: 1.078 ± 0.668
2.156PheAsn: 2.156 ± 0.498
1.887PhePro: 1.887 ± 1.145
1.078PheGln: 1.078 ± 0.556
2.965PheArg: 2.965 ± 0.8
2.965PheSer: 2.965 ± 0.947
2.965PheThr: 2.965 ± 0.422
1.078PheVal: 1.078 ± 0.361
0.0PheTrp: 0.0 ± 0.0
1.617PheTyr: 1.617 ± 1.059
0.0PheXaa: 0.0 ± 0.0
Gly
3.235GlyAla: 3.235 ± 1.328
3.235GlyCys: 3.235 ± 0.94
3.504GlyAsp: 3.504 ± 0.85
4.852GlyGlu: 4.852 ± 0.458
4.043GlyPhe: 4.043 ± 0.854
3.504GlyGly: 3.504 ± 0.717
2.426GlyHis: 2.426 ± 0.439
5.121GlyIle: 5.121 ± 0.601
3.235GlyLys: 3.235 ± 1.611
4.852GlyLeu: 4.852 ± 0.845
1.348GlyMet: 1.348 ± 0.385
2.965GlyAsn: 2.965 ± 0.747
2.695GlyPro: 2.695 ± 0.284
2.156GlyGln: 2.156 ± 0.717
3.504GlyArg: 3.504 ± 0.85
5.93GlySer: 5.93 ± 2.096
2.965GlyThr: 2.965 ± 0.819
3.504GlyVal: 3.504 ± 1.268
1.348GlyTrp: 1.348 ± 0.689
0.539GlyTyr: 0.539 ± 0.547
0.0GlyXaa: 0.0 ± 0.0
His
1.887HisAla: 1.887 ± 0.415
0.27HisCys: 0.27 ± 0.257
0.809HisAsp: 0.809 ± 0.491
1.887HisGlu: 1.887 ± 0.509
0.27HisPhe: 0.27 ± 0.164
1.348HisGly: 1.348 ± 0.391
0.0HisHis: 0.0 ± 0.0
0.539HisIle: 0.539 ± 0.185
1.078HisLys: 1.078 ± 0.668
1.887HisLeu: 1.887 ± 0.822
0.539HisMet: 0.539 ± 0.547
0.27HisAsn: 0.27 ± 0.164
0.809HisPro: 0.809 ± 0.772
1.348HisGln: 1.348 ± 0.509
1.348HisArg: 1.348 ± 0.818
0.539HisSer: 0.539 ± 0.515
0.539HisThr: 0.539 ± 0.547
1.348HisVal: 1.348 ± 0.509
0.539HisTrp: 0.539 ± 0.185
2.156HisTyr: 2.156 ± 0.695
0.0HisXaa: 0.0 ± 0.0
Ile
2.156IleAla: 2.156 ± 0.345
1.617IleCys: 1.617 ± 0.643
3.774IleAsp: 3.774 ± 0.831
5.121IleGlu: 5.121 ± 1.242
2.156IlePhe: 2.156 ± 0.587
2.965IleGly: 2.965 ± 0.43
0.539IleHis: 0.539 ± 0.515
3.774IleIle: 3.774 ± 0.592
5.121IleLys: 5.121 ± 1.649
7.817IleLeu: 7.817 ± 1.101
1.078IleMet: 1.078 ± 0.668
2.695IleAsn: 2.695 ± 0.892
1.887IlePro: 1.887 ± 0.587
3.235IleGln: 3.235 ± 0.777
3.774IleArg: 3.774 ± 2.141
7.278IleSer: 7.278 ± 1.163
4.043IleThr: 4.043 ± 0.599
2.965IleVal: 2.965 ± 1.834
0.27IleTrp: 0.27 ± 0.164
0.809IleTyr: 0.809 ± 0.491
0.0IleXaa: 0.0 ± 0.0
Lys
4.582LysAla: 4.582 ± 2.861
0.809LysCys: 0.809 ± 0.772
3.504LysAsp: 3.504 ± 1.601
6.469LysGlu: 6.469 ± 0.822
1.348LysPhe: 1.348 ± 0.509
4.582LysGly: 4.582 ± 1.135
1.078LysHis: 1.078 ± 0.361
3.235LysIle: 3.235 ± 0.78
5.121LysLys: 5.121 ± 1.218
4.852LysLeu: 4.852 ± 1.662
2.695LysMet: 2.695 ± 1.245
2.965LysAsn: 2.965 ± 1.158
1.887LysPro: 1.887 ± 1.084
1.887LysGln: 1.887 ± 0.587
3.504LysArg: 3.504 ± 1.227
5.121LysSer: 5.121 ± 0.732
3.774LysThr: 3.774 ± 1.175
5.121LysVal: 5.121 ± 1.552
1.348LysTrp: 1.348 ± 0.923
1.348LysTyr: 1.348 ± 0.648
0.0LysXaa: 0.0 ± 0.0
Leu
6.469LeuAla: 6.469 ± 0.943
1.617LeuCys: 1.617 ± 0.771
5.66LeuAsp: 5.66 ± 1.165
7.547LeuGlu: 7.547 ± 2.525
4.043LeuPhe: 4.043 ± 1.338
6.739LeuGly: 6.739 ± 0.957
1.617LeuHis: 1.617 ± 0.424
7.278LeuIle: 7.278 ± 0.371
7.278LeuLys: 7.278 ± 1.719
7.817LeuLeu: 7.817 ± 2.516
2.156LeuMet: 2.156 ± 0.626
3.504LeuAsn: 3.504 ± 0.134
3.504LeuPro: 3.504 ± 1.661
4.043LeuGln: 4.043 ± 1.064
4.852LeuArg: 4.852 ± 1.18
10.512LeuSer: 10.512 ± 1.407
5.93LeuThr: 5.93 ± 2.19
6.199LeuVal: 6.199 ± 1.437
1.617LeuTrp: 1.617 ± 0.48
1.617LeuTyr: 1.617 ± 0.362
0.0LeuXaa: 0.0 ± 0.0
Met
1.887MetAla: 1.887 ± 1.34
0.809MetCys: 0.809 ± 0.491
0.809MetAsp: 0.809 ± 0.527
2.695MetGlu: 2.695 ± 0.819
0.27MetPhe: 0.27 ± 0.257
1.887MetGly: 1.887 ± 1.086
0.809MetHis: 0.809 ± 0.236
1.887MetIle: 1.887 ± 0.822
1.887MetLys: 1.887 ± 0.505
3.504MetLeu: 3.504 ± 0.878
1.078MetMet: 1.078 ± 0.361
0.539MetAsn: 0.539 ± 0.468
0.539MetPro: 0.539 ± 0.185
0.27MetGln: 0.27 ± 0.164
0.809MetArg: 0.809 ± 0.236
2.426MetSer: 2.426 ± 0.982
2.156MetThr: 2.156 ± 0.695
1.887MetVal: 1.887 ± 0.505
0.0MetTrp: 0.0 ± 0.0
0.27MetTyr: 0.27 ± 0.164
0.0MetXaa: 0.0 ± 0.0
Asn
1.348AsnAla: 1.348 ± 0.759
1.348AsnCys: 1.348 ± 1.287
1.617AsnAsp: 1.617 ± 0.664
1.348AsnGlu: 1.348 ± 0.648
2.156AsnPhe: 2.156 ± 0.982
1.078AsnGly: 1.078 ± 0.735
0.0AsnHis: 0.0 ± 0.0
2.426AsnIle: 2.426 ± 0.894
1.348AsnLys: 1.348 ± 0.936
4.043AsnLeu: 4.043 ± 1.307
1.078AsnMet: 1.078 ± 0.389
1.078AsnAsn: 1.078 ± 0.37
3.504AsnPro: 3.504 ± 0.811
1.887AsnGln: 1.887 ± 0.822
1.078AsnArg: 1.078 ± 1.114
2.965AsnSer: 2.965 ± 0.781
0.809AsnThr: 0.809 ± 0.512
2.695AsnVal: 2.695 ± 0.486
1.617AsnTrp: 1.617 ± 0.555
1.078AsnTyr: 1.078 ± 0.654
0.0AsnXaa: 0.0 ± 0.0
Pro
1.348ProAla: 1.348 ± 0.469
0.539ProCys: 0.539 ± 0.515
3.235ProAsp: 3.235 ± 0.959
2.156ProGlu: 2.156 ± 0.52
1.887ProPhe: 1.887 ± 0.314
2.695ProGly: 2.695 ± 0.486
0.539ProHis: 0.539 ± 0.327
2.426ProIle: 2.426 ± 1.946
2.426ProLys: 2.426 ± 0.58
3.235ProLeu: 3.235 ± 0.564
1.078ProMet: 1.078 ± 1.143
0.809ProAsn: 0.809 ± 0.236
1.887ProPro: 1.887 ± 0.923
2.156ProGln: 2.156 ± 0.851
2.156ProArg: 2.156 ± 0.962
1.887ProSer: 1.887 ± 0.771
2.156ProThr: 2.156 ± 2.019
2.965ProVal: 2.965 ± 0.71
0.809ProTrp: 0.809 ± 0.491
0.809ProTyr: 0.809 ± 0.417
0.0ProXaa: 0.0 ± 0.0
Gln
1.617GlnAla: 1.617 ± 0.702
1.617GlnCys: 1.617 ± 1.179
2.156GlnAsp: 2.156 ± 0.982
2.965GlnGlu: 2.965 ± 0.8
1.887GlnPhe: 1.887 ± 0.508
3.504GlnGly: 3.504 ± 1.322
1.078GlnHis: 1.078 ± 0.37
2.695GlnIle: 2.695 ± 0.628
2.156GlnLys: 2.156 ± 0.982
2.156GlnLeu: 2.156 ± 1.094
1.617GlnMet: 1.617 ± 0.981
2.156GlnAsn: 2.156 ± 0.478
0.809GlnPro: 0.809 ± 0.742
0.539GlnGln: 0.539 ± 0.515
1.617GlnArg: 1.617 ± 0.362
1.078GlnSer: 1.078 ± 0.654
2.156GlnThr: 2.156 ± 0.924
2.156GlnVal: 2.156 ± 0.91
0.0GlnTrp: 0.0 ± 0.0
0.539GlnTyr: 0.539 ± 0.185
0.0GlnXaa: 0.0 ± 0.0
Arg
3.774ArgAla: 3.774 ± 0.826
1.348ArgCys: 1.348 ± 0.392
2.156ArgAsp: 2.156 ± 1.018
3.235ArgGlu: 3.235 ± 0.564
2.426ArgPhe: 2.426 ± 0.867
4.313ArgGly: 4.313 ± 0.566
1.617ArgHis: 1.617 ± 0.472
5.121ArgIle: 5.121 ± 1.014
4.852ArgLys: 4.852 ± 1.851
5.66ArgLeu: 5.66 ± 0.819
2.156ArgMet: 2.156 ± 1.428
1.078ArgAsn: 1.078 ± 0.654
2.156ArgPro: 2.156 ± 0.851
1.617ArgGln: 1.617 ± 0.664
3.774ArgArg: 3.774 ± 1.644
5.66ArgSer: 5.66 ± 0.941
2.965ArgThr: 2.965 ± 0.947
4.043ArgVal: 4.043 ± 1.297
1.348ArgTrp: 1.348 ± 0.765
0.539ArgTyr: 0.539 ± 0.185
0.0ArgXaa: 0.0 ± 0.0
Ser
4.313SerAla: 4.313 ± 1.724
4.043SerCys: 4.043 ± 1.01
5.66SerAsp: 5.66 ± 1.643
3.774SerGlu: 3.774 ± 0.94
2.965SerPhe: 2.965 ± 1.752
8.356SerGly: 8.356 ± 1.137
2.426SerHis: 2.426 ± 0.334
5.391SerIle: 5.391 ± 0.972
4.313SerLys: 4.313 ± 1.51
9.434SerLeu: 9.434 ± 0.936
1.348SerMet: 1.348 ± 0.592
3.235SerAsn: 3.235 ± 0.625
2.695SerPro: 2.695 ± 0.356
3.504SerGln: 3.504 ± 0.657
6.739SerArg: 6.739 ± 0.599
6.469SerSer: 6.469 ± 0.9
4.313SerThr: 4.313 ± 2.001
4.582SerVal: 4.582 ± 0.628
1.348SerTrp: 1.348 ± 1.062
1.348SerTyr: 1.348 ± 1.24
0.0SerXaa: 0.0 ± 0.0
Thr
2.156ThrAla: 2.156 ± 0.695
1.348ThrCys: 1.348 ± 0.923
3.235ThrAsp: 3.235 ± 0.657
5.121ThrGlu: 5.121 ± 1.242
2.695ThrPhe: 2.695 ± 0.954
2.426ThrGly: 2.426 ± 0.707
1.348ThrHis: 1.348 ± 0.469
2.426ThrIle: 2.426 ± 0.334
3.235ThrLys: 3.235 ± 0.953
5.66ThrLeu: 5.66 ± 1.272
1.348ThrMet: 1.348 ± 0.627
2.156ThrAsn: 2.156 ± 0.619
2.426ThrPro: 2.426 ± 1.952
1.887ThrGln: 1.887 ± 0.751
4.043ThrArg: 4.043 ± 1.664
5.66ThrSer: 5.66 ± 1.658
2.695ThrThr: 2.695 ± 0.782
2.695ThrVal: 2.695 ± 0.939
0.539ThrTrp: 0.539 ± 0.468
1.078ThrTyr: 1.078 ± 0.426
0.0ThrXaa: 0.0 ± 0.0
Val
2.426ValAla: 2.426 ± 1.434
1.887ValCys: 1.887 ± 0.564
3.504ValAsp: 3.504 ± 1.61
2.965ValGlu: 2.965 ± 0.851
3.774ValPhe: 3.774 ± 0.827
4.852ValGly: 4.852 ± 1.025
1.617ValHis: 1.617 ± 0.621
3.235ValIle: 3.235 ± 0.78
4.852ValLys: 4.852 ± 0.309
7.817ValLeu: 7.817 ± 1.848
0.809ValMet: 0.809 ± 0.236
1.617ValAsn: 1.617 ± 0.362
2.426ValPro: 2.426 ± 0.761
0.809ValGln: 0.809 ± 0.742
4.043ValArg: 4.043 ± 0.891
5.391ValSer: 5.391 ± 1.272
2.965ValThr: 2.965 ± 0.439
3.774ValVal: 3.774 ± 0.798
1.078ValTrp: 1.078 ± 0.361
2.156ValTyr: 2.156 ± 0.345
0.0ValXaa: 0.0 ± 0.0
Trp
1.078TrpAla: 1.078 ± 0.361
0.27TrpCys: 0.27 ± 0.164
0.27TrpAsp: 0.27 ± 0.257
0.809TrpGlu: 0.809 ± 0.453
1.348TrpPhe: 1.348 ± 0.466
0.539TrpGly: 0.539 ± 0.327
0.27TrpHis: 0.27 ± 0.164
1.348TrpIle: 1.348 ± 0.392
1.078TrpLys: 1.078 ± 0.735
1.348TrpLeu: 1.348 ± 0.592
0.0TrpMet: 0.0 ± 0.0
0.27TrpAsn: 0.27 ± 0.164
0.539TrpPro: 0.539 ± 1.225
0.809TrpGln: 0.809 ± 0.482
1.617TrpArg: 1.617 ± 0.362
0.809TrpSer: 0.809 ± 0.417
0.539TrpThr: 0.539 ± 0.468
0.809TrpVal: 0.809 ± 0.491
0.0TrpTrp: 0.0 ± 0.0
0.27TrpTyr: 0.27 ± 0.164
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.078TyrAla: 1.078 ± 0.361
0.27TyrCys: 0.27 ± 0.257
0.27TyrAsp: 0.27 ± 0.257
0.809TyrGlu: 0.809 ± 0.236
1.887TyrPhe: 1.887 ± 1.16
0.809TyrGly: 0.809 ± 0.742
1.348TyrHis: 1.348 ± 0.818
1.617TyrIle: 1.617 ± 0.424
1.348TyrLys: 1.348 ± 0.818
2.695TyrLeu: 2.695 ± 1.176
0.539TyrMet: 0.539 ± 0.185
0.27TyrAsn: 0.27 ± 0.164
1.617TyrPro: 1.617 ± 1.286
0.809TyrGln: 0.809 ± 0.453
1.887TyrArg: 1.887 ± 0.415
1.887TyrSer: 1.887 ± 0.851
1.078TyrThr: 1.078 ± 0.547
1.078TyrVal: 1.078 ± 0.37
0.27TyrTrp: 0.27 ± 0.613
0.27TyrTyr: 0.27 ± 0.164
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3711 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski