Amino acid dipepetide frequency for Aconitum latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.369AlaAla: 5.369 ± 1.6
0.358AlaCys: 0.358 ± 0.188
3.579AlaAsp: 3.579 ± 0.662
5.369AlaGlu: 5.369 ± 2.85
3.579AlaPhe: 3.579 ± 1.007
4.295AlaGly: 4.295 ± 1.145
1.79AlaHis: 1.79 ± 1.021
4.653AlaIle: 4.653 ± 1.383
5.369AlaLys: 5.369 ± 1.367
10.379AlaLeu: 10.379 ± 4.828
1.432AlaMet: 1.432 ± 1.996
2.505AlaAsn: 2.505 ± 0.914
2.505AlaPro: 2.505 ± 1.086
3.221AlaGln: 3.221 ± 1.245
4.653AlaArg: 4.653 ± 1.54
5.011AlaSer: 5.011 ± 1.012
2.505AlaThr: 2.505 ± 1.207
5.369AlaVal: 5.369 ± 1.234
0.0AlaTrp: 0.0 ± 0.0
1.79AlaTyr: 1.79 ± 0.639
0.0AlaXaa: 0.0 ± 0.0
Cys
1.79CysAla: 1.79 ± 0.939
1.074CysCys: 1.074 ± 0.563
1.79CysAsp: 1.79 ± 0.723
2.147CysGlu: 2.147 ± 1.127
2.505CysPhe: 2.505 ± 1.416
2.505CysGly: 2.505 ± 1.835
0.716CysHis: 0.716 ± 1.452
1.074CysIle: 1.074 ± 0.563
2.505CysLys: 2.505 ± 1.473
2.147CysLeu: 2.147 ± 0.796
0.0CysMet: 0.0 ± 0.0
0.716CysAsn: 0.716 ± 1.176
2.147CysPro: 2.147 ± 1.139
0.0CysGln: 0.0 ± 0.0
2.147CysArg: 2.147 ± 0.613
1.074CysSer: 1.074 ± 1.104
2.505CysThr: 2.505 ± 1.315
2.505CysVal: 2.505 ± 1.406
0.0CysTrp: 0.0 ± 0.0
0.358CysTyr: 0.358 ± 0.188
0.0CysXaa: 0.0 ± 0.0
Asp
2.505AspAla: 2.505 ± 1.549
2.505AspCys: 2.505 ± 0.812
5.369AspAsp: 5.369 ± 2.105
5.369AspGlu: 5.369 ± 1.909
1.074AspPhe: 1.074 ± 0.681
3.221AspGly: 3.221 ± 1.319
0.716AspHis: 0.716 ± 0.534
2.505AspIle: 2.505 ± 1.406
1.79AspLys: 1.79 ± 0.635
2.505AspLeu: 2.505 ± 0.647
1.432AspMet: 1.432 ± 1.029
0.716AspAsn: 0.716 ± 0.376
2.147AspPro: 2.147 ± 1.173
1.432AspGln: 1.432 ± 0.751
4.295AspArg: 4.295 ± 1.51
4.295AspSer: 4.295 ± 1.529
1.432AspThr: 1.432 ± 0.751
3.579AspVal: 3.579 ± 1.279
1.074AspTrp: 1.074 ± 0.504
2.863AspTyr: 2.863 ± 1.083
0.0AspXaa: 0.0 ± 0.0
Glu
5.369GluAla: 5.369 ± 2.105
1.074GluCys: 1.074 ± 1.077
2.505GluAsp: 2.505 ± 0.914
5.011GluGlu: 5.011 ± 1.625
3.579GluPhe: 3.579 ± 1.204
6.442GluGly: 6.442 ± 1.353
1.79GluHis: 1.79 ± 1.038
2.505GluIle: 2.505 ± 0.914
3.221GluLys: 3.221 ± 1.166
7.158GluLeu: 7.158 ± 2.214
1.074GluMet: 1.074 ± 0.563
2.147GluAsn: 2.147 ± 0.764
2.863GluPro: 2.863 ± 1.151
0.358GluGln: 0.358 ± 0.188
4.295GluArg: 4.295 ± 1.478
4.653GluSer: 4.653 ± 1.93
2.147GluThr: 2.147 ± 1.601
6.084GluVal: 6.084 ± 1.119
1.074GluTrp: 1.074 ± 0.504
1.074GluTyr: 1.074 ± 0.57
0.0GluXaa: 0.0 ± 0.0
Phe
4.653PheAla: 4.653 ± 1.554
0.716PheCys: 0.716 ± 0.376
3.937PheAsp: 3.937 ± 1.049
4.295PheGlu: 4.295 ± 1.171
1.432PhePhe: 1.432 ± 0.751
3.937PheGly: 3.937 ± 1.117
0.716PheHis: 0.716 ± 0.376
3.579PheIle: 3.579 ± 1.241
1.79PheLys: 1.79 ± 0.939
5.727PheLeu: 5.727 ± 1.287
1.074PheMet: 1.074 ± 0.563
2.505PheAsn: 2.505 ± 1.601
0.358PhePro: 0.358 ± 0.188
3.579PheGln: 3.579 ± 1.89
3.221PheArg: 3.221 ± 1.22
1.432PheSer: 1.432 ± 0.751
3.221PheThr: 3.221 ± 1.22
2.505PheVal: 2.505 ± 0.812
0.358PheTrp: 0.358 ± 0.188
0.716PheTyr: 0.716 ± 0.376
0.0PheXaa: 0.0 ± 0.0
Gly
2.863GlyAla: 2.863 ± 1.027
2.147GlyCys: 2.147 ± 0.796
5.727GlyAsp: 5.727 ± 1.052
3.579GlyGlu: 3.579 ± 0.959
2.863GlyPhe: 2.863 ± 1.428
2.863GlyGly: 2.863 ± 2.33
1.074GlyHis: 1.074 ± 1.104
4.653GlyIle: 4.653 ± 1.675
4.653GlyLys: 4.653 ± 1.621
9.306GlyLeu: 9.306 ± 3.409
1.432GlyMet: 1.432 ± 0.751
2.147GlyAsn: 2.147 ± 1.008
2.147GlyPro: 2.147 ± 0.639
0.716GlyGln: 0.716 ± 0.376
5.011GlyArg: 5.011 ± 1.226
1.432GlySer: 1.432 ± 0.751
3.937GlyThr: 3.937 ± 1.566
5.011GlyVal: 5.011 ± 0.757
1.074GlyTrp: 1.074 ± 0.563
1.074GlyTyr: 1.074 ± 0.563
0.0GlyXaa: 0.0 ± 0.0
His
1.074HisAla: 1.074 ± 1.104
1.074HisCys: 1.074 ± 1.337
0.358HisAsp: 0.358 ± 0.188
2.505HisGlu: 2.505 ± 1.315
0.358HisPhe: 0.358 ± 0.188
0.716HisGly: 0.716 ± 1.176
0.358HisHis: 0.358 ± 0.188
2.147HisIle: 2.147 ± 0.796
2.863HisLys: 2.863 ± 1.076
3.221HisLeu: 3.221 ± 1.69
0.358HisMet: 0.358 ± 0.188
2.147HisAsn: 2.147 ± 2.407
1.074HisPro: 1.074 ± 0.57
0.358HisGln: 0.358 ± 0.188
1.79HisArg: 1.79 ± 0.912
2.863HisSer: 2.863 ± 1.271
0.0HisThr: 0.0 ± 0.0
1.074HisVal: 1.074 ± 1.642
0.0HisTrp: 0.0 ± 0.0
1.074HisTyr: 1.074 ± 0.563
0.0HisXaa: 0.0 ± 0.0
Ile
5.369IleAla: 5.369 ± 1.98
2.863IleCys: 2.863 ± 0.797
1.432IleAsp: 1.432 ± 0.773
3.579IleGlu: 3.579 ± 0.992
2.863IlePhe: 2.863 ± 1.076
1.074IleGly: 1.074 ± 0.563
0.716IleHis: 0.716 ± 0.623
2.505IleIle: 2.505 ± 1.282
4.295IleLys: 4.295 ± 0.847
3.221IleLeu: 3.221 ± 1.193
2.505IleMet: 2.505 ± 1.029
3.221IleAsn: 3.221 ± 2.451
2.147IlePro: 2.147 ± 0.811
1.432IleGln: 1.432 ± 1.264
3.579IleArg: 3.579 ± 0.955
3.221IleSer: 3.221 ± 0.915
2.505IleThr: 2.505 ± 1.282
2.505IleVal: 2.505 ± 1.315
1.074IleTrp: 1.074 ± 0.563
2.505IleTyr: 2.505 ± 0.881
0.0IleXaa: 0.0 ± 0.0
Lys
4.295LysAla: 4.295 ± 1.313
1.074LysCys: 1.074 ± 0.681
3.937LysAsp: 3.937 ± 1.41
1.074LysGlu: 1.074 ± 0.563
2.505LysPhe: 2.505 ± 1.315
2.505LysGly: 2.505 ± 1.005
1.074LysHis: 1.074 ± 0.57
1.432LysIle: 1.432 ± 1.068
2.863LysLys: 2.863 ± 1.027
8.232LysLeu: 8.232 ± 1.719
1.074LysMet: 1.074 ± 0.479
1.79LysAsn: 1.79 ± 0.635
2.505LysPro: 2.505 ± 0.978
1.432LysGln: 1.432 ± 1.061
5.369LysArg: 5.369 ± 1.434
3.937LysSer: 3.937 ± 1.039
3.937LysThr: 3.937 ± 1.081
3.221LysVal: 3.221 ± 1.245
1.074LysTrp: 1.074 ± 1.12
1.79LysTyr: 1.79 ± 0.639
0.0LysXaa: 0.0 ± 0.0
Leu
6.084LeuAla: 6.084 ± 0.523
3.221LeuCys: 3.221 ± 1.345
4.653LeuAsp: 4.653 ± 1.455
7.516LeuGlu: 7.516 ± 2.659
2.863LeuPhe: 2.863 ± 1.503
6.442LeuGly: 6.442 ± 1.655
3.579LeuHis: 3.579 ± 1.694
3.937LeuIle: 3.937 ± 1.009
5.727LeuLys: 5.727 ± 1.922
8.232LeuLeu: 8.232 ± 5.767
1.074LeuMet: 1.074 ± 0.654
5.011LeuAsn: 5.011 ± 1.431
6.084LeuPro: 6.084 ± 2.013
3.221LeuGln: 3.221 ± 0.808
7.516LeuArg: 7.516 ± 1.638
9.664LeuSer: 9.664 ± 3.706
5.727LeuThr: 5.727 ± 1.567
7.874LeuVal: 7.874 ± 4.383
0.716LeuTrp: 0.716 ± 0.376
3.937LeuTyr: 3.937 ± 1.678
0.0LeuXaa: 0.0 ± 0.0
Met
2.505MetAla: 2.505 ± 1.029
0.716MetCys: 0.716 ± 0.376
1.074MetAsp: 1.074 ± 0.57
1.432MetGlu: 1.432 ± 0.751
0.358MetPhe: 0.358 ± 0.188
1.432MetGly: 1.432 ± 0.769
0.358MetHis: 0.358 ± 0.188
0.716MetIle: 0.716 ± 0.376
1.074MetLys: 1.074 ± 0.897
1.79MetLeu: 1.79 ± 0.635
0.716MetMet: 0.716 ± 0.534
0.358MetAsn: 0.358 ± 0.914
1.074MetPro: 1.074 ± 0.563
0.716MetGln: 0.716 ± 0.376
2.147MetArg: 2.147 ± 0.764
1.074MetSer: 1.074 ± 0.504
0.358MetThr: 0.358 ± 0.622
1.432MetVal: 1.432 ± 1.061
0.0MetTrp: 0.0 ± 0.0
0.716MetTyr: 0.716 ± 0.534
0.0MetXaa: 0.0 ± 0.0
Asn
2.863AsnAla: 2.863 ± 1.13
2.147AsnCys: 2.147 ± 0.811
2.147AsnAsp: 2.147 ± 0.897
2.147AsnGlu: 2.147 ± 1.563
1.432AsnPhe: 1.432 ± 0.751
3.579AsnGly: 3.579 ± 1.007
1.074AsnHis: 1.074 ± 0.563
1.074AsnIle: 1.074 ± 0.57
1.79AsnLys: 1.79 ± 1.696
6.442AsnLeu: 6.442 ± 2.567
1.432AsnMet: 1.432 ± 0.755
1.79AsnAsn: 1.79 ± 1.958
1.79AsnPro: 1.79 ± 1.021
0.716AsnGln: 0.716 ± 0.534
3.937AsnArg: 3.937 ± 2.66
3.221AsnSer: 3.221 ± 2.103
1.79AsnThr: 1.79 ± 0.684
0.716AsnVal: 0.716 ± 0.376
0.358AsnTrp: 0.358 ± 0.188
3.221AsnTyr: 3.221 ± 2.005
0.0AsnXaa: 0.0 ± 0.0
Pro
2.863ProAla: 2.863 ± 0.707
1.432ProCys: 1.432 ± 1.061
2.863ProAsp: 2.863 ± 0.707
2.147ProGlu: 2.147 ± 0.764
1.79ProPhe: 1.79 ± 0.639
3.579ProGly: 3.579 ± 0.662
1.79ProHis: 1.79 ± 2.274
2.505ProIle: 2.505 ± 1.13
1.79ProLys: 1.79 ± 0.939
3.579ProLeu: 3.579 ± 1.092
0.716ProMet: 0.716 ± 0.376
1.79ProAsn: 1.79 ± 2.302
2.505ProPro: 2.505 ± 2.644
1.074ProGln: 1.074 ± 0.563
2.863ProArg: 2.863 ± 1.651
1.79ProSer: 1.79 ± 1.911
2.863ProThr: 2.863 ± 1.55
1.432ProVal: 1.432 ± 0.769
0.716ProTrp: 0.716 ± 1.176
1.79ProTyr: 1.79 ± 0.635
0.0ProXaa: 0.0 ± 0.0
Gln
3.579GlnAla: 3.579 ± 1.527
0.358GlnCys: 0.358 ± 0.723
1.074GlnAsp: 1.074 ± 0.563
1.074GlnGlu: 1.074 ± 0.57
1.79GlnPhe: 1.79 ± 0.939
1.79GlnGly: 1.79 ± 0.86
0.358GlnHis: 0.358 ± 0.188
1.79GlnIle: 1.79 ± 0.684
0.716GlnLys: 0.716 ± 0.376
2.863GlnLeu: 2.863 ± 1.076
0.358GlnMet: 0.358 ± 0.188
0.716GlnAsn: 0.716 ± 0.376
1.79GlnPro: 1.79 ± 1.038
1.074GlnGln: 1.074 ± 0.563
0.716GlnArg: 0.716 ± 0.623
4.653GlnSer: 4.653 ± 1.403
2.505GlnThr: 2.505 ± 0.647
1.79GlnVal: 1.79 ± 1.05
0.0GlnTrp: 0.0 ± 0.0
0.716GlnTyr: 0.716 ± 0.534
0.0GlnXaa: 0.0 ± 0.0
Arg
7.516ArgAla: 7.516 ± 1.942
2.863ArgCys: 2.863 ± 3.865
2.505ArgAsp: 2.505 ± 1.086
5.727ArgGlu: 5.727 ± 1.331
3.937ArgPhe: 3.937 ± 0.983
5.011ArgGly: 5.011 ± 1.133
1.79ArgHis: 1.79 ± 0.639
3.221ArgIle: 3.221 ± 1.134
3.221ArgLys: 3.221 ± 0.764
5.369ArgLeu: 5.369 ± 1.343
1.432ArgMet: 1.432 ± 0.751
3.221ArgAsn: 3.221 ± 1.166
3.221ArgPro: 3.221 ± 3.24
0.716ArgGln: 0.716 ± 0.534
5.011ArgArg: 5.011 ± 1.482
2.147ArgSer: 2.147 ± 0.746
3.221ArgThr: 3.221 ± 1.193
4.295ArgVal: 4.295 ± 1.401
1.432ArgTrp: 1.432 ± 0.576
2.863ArgTyr: 2.863 ± 1.503
0.0ArgXaa: 0.0 ± 0.0
Ser
3.937SerAla: 3.937 ± 0.692
2.505SerCys: 2.505 ± 1.315
2.863SerAsp: 2.863 ± 0.707
3.579SerGlu: 3.579 ± 0.992
5.011SerPhe: 5.011 ± 1.399
5.011SerGly: 5.011 ± 1.185
3.579SerHis: 3.579 ± 1.213
2.863SerIle: 2.863 ± 2.413
4.295SerLys: 4.295 ± 1.567
5.011SerLeu: 5.011 ± 0.792
0.358SerMet: 0.358 ± 0.188
2.863SerAsn: 2.863 ± 1.027
1.432SerPro: 1.432 ± 0.751
2.147SerGln: 2.147 ± 1.127
2.863SerArg: 2.863 ± 0.854
4.295SerSer: 4.295 ± 0.847
4.653SerThr: 4.653 ± 1.861
4.295SerVal: 4.295 ± 1.52
0.358SerTrp: 0.358 ± 0.188
3.221SerTyr: 3.221 ± 1.22
0.0SerXaa: 0.0 ± 0.0
Thr
3.579ThrAla: 3.579 ± 1.896
0.358ThrCys: 0.358 ± 0.188
1.432ThrAsp: 1.432 ± 0.576
2.863ThrGlu: 2.863 ± 1.519
8.232ThrPhe: 8.232 ± 2.047
4.653ThrGly: 4.653 ± 1.14
1.432ThrHis: 1.432 ± 0.542
3.937ThrIle: 3.937 ± 1.596
2.863ThrLys: 2.863 ± 2.484
4.653ThrLeu: 4.653 ± 0.68
1.432ThrMet: 1.432 ± 0.751
3.579ThrAsn: 3.579 ± 2.288
1.432ThrPro: 1.432 ± 1.143
1.074ThrGln: 1.074 ± 0.563
3.221ThrArg: 3.221 ± 0.808
2.505ThrSer: 2.505 ± 1.406
2.863ThrThr: 2.863 ± 1.076
1.432ThrVal: 1.432 ± 0.751
0.716ThrTrp: 0.716 ± 0.534
1.432ThrTyr: 1.432 ± 1.004
0.0ThrXaa: 0.0 ± 0.0
Val
5.011ValAla: 5.011 ± 0.985
1.79ValCys: 1.79 ± 0.635
2.147ValAsp: 2.147 ± 0.811
2.505ValGlu: 2.505 ± 1.381
1.074ValPhe: 1.074 ± 0.563
3.221ValGly: 3.221 ± 1.278
1.79ValHis: 1.79 ± 0.639
5.011ValIle: 5.011 ± 0.938
2.147ValLys: 2.147 ± 1.127
9.306ValLeu: 9.306 ± 5.4
0.716ValMet: 0.716 ± 0.534
3.221ValAsn: 3.221 ± 0.928
1.432ValPro: 1.432 ± 0.773
3.937ValGln: 3.937 ± 1.817
3.579ValArg: 3.579 ± 1.878
3.579ValSer: 3.579 ± 0.626
4.653ValThr: 4.653 ± 1.784
5.011ValVal: 5.011 ± 2.502
0.716ValTrp: 0.716 ± 1.782
1.79ValTyr: 1.79 ± 0.639
0.0ValXaa: 0.0 ± 0.0
Trp
0.716TrpAla: 0.716 ± 1.407
0.716TrpCys: 0.716 ± 0.376
0.358TrpAsp: 0.358 ± 0.188
0.358TrpGlu: 0.358 ± 0.723
0.716TrpPhe: 0.716 ± 0.376
0.358TrpGly: 0.358 ± 0.188
0.358TrpHis: 0.358 ± 0.188
0.358TrpIle: 0.358 ± 0.723
0.0TrpLys: 0.0 ± 0.0
1.074TrpLeu: 1.074 ± 1.104
0.0TrpMet: 0.0 ± 0.0
0.716TrpAsn: 0.716 ± 0.534
1.074TrpPro: 1.074 ± 0.897
0.358TrpGln: 0.358 ± 0.188
1.432TrpArg: 1.432 ± 0.677
1.074TrpSer: 1.074 ± 0.563
0.0TrpThr: 0.0 ± 0.0
0.716TrpVal: 0.716 ± 0.376
0.358TrpTrp: 0.358 ± 0.829
0.716TrpTyr: 0.716 ± 0.376
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.79TyrAla: 1.79 ± 1.518
0.716TyrCys: 0.716 ± 0.534
1.432TyrAsp: 1.432 ± 0.542
2.147TyrGlu: 2.147 ± 0.746
1.79TyrPhe: 1.79 ± 1.478
1.074TyrGly: 1.074 ± 0.57
0.358TyrHis: 0.358 ± 0.188
2.147TyrIle: 2.147 ± 1.127
2.147TyrLys: 2.147 ± 2.209
2.863TyrLeu: 2.863 ± 1.076
1.074TyrMet: 1.074 ± 0.504
2.505TyrAsn: 2.505 ± 0.914
2.147TyrPro: 2.147 ± 1.127
2.147TyrGln: 2.147 ± 1.127
1.074TyrArg: 1.074 ± 0.563
3.221TyrSer: 3.221 ± 1.69
2.863TyrThr: 2.863 ± 1.968
1.79TyrVal: 1.79 ± 0.635
0.358TyrTrp: 0.358 ± 0.188
1.074TyrTyr: 1.074 ± 1.104
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2795 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski