Amino acid dipepetide frequency for Garlic virus D

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.162AlaAla: 4.162 ± 1.415
1.892AlaCys: 1.892 ± 0.714
1.892AlaAsp: 1.892 ± 0.728
3.405AlaGlu: 3.405 ± 0.807
3.027AlaPhe: 3.027 ± 1.001
4.162AlaGly: 4.162 ± 1.485
3.784AlaHis: 3.784 ± 1.091
1.513AlaIle: 1.513 ± 0.775
6.81AlaLys: 6.81 ± 2.345
8.324AlaLeu: 8.324 ± 2.388
1.892AlaMet: 1.892 ± 1.095
4.54AlaAsn: 4.54 ± 1.157
3.405AlaPro: 3.405 ± 2.588
2.649AlaGln: 2.649 ± 0.661
3.784AlaArg: 3.784 ± 1.762
2.649AlaSer: 2.649 ± 1.745
5.675AlaThr: 5.675 ± 1.32
4.162AlaVal: 4.162 ± 1.434
0.757AlaTrp: 0.757 ± 0.518
3.784AlaTyr: 3.784 ± 1.59
0.0AlaXaa: 0.0 ± 0.0
Cys
0.757CysAla: 0.757 ± 0.559
0.757CysCys: 0.757 ± 1.259
2.27CysAsp: 2.27 ± 0.819
1.135CysGlu: 1.135 ± 0.657
1.135CysPhe: 1.135 ± 0.57
2.27CysGly: 2.27 ± 1.197
0.378CysHis: 0.378 ± 0.219
0.0CysIle: 0.0 ± 0.0
1.135CysLys: 1.135 ± 1.171
1.892CysLeu: 1.892 ± 0.639
0.378CysMet: 0.378 ± 0.411
0.757CysAsn: 0.757 ± 0.438
1.135CysPro: 1.135 ± 0.884
0.378CysGln: 0.378 ± 0.219
1.135CysArg: 1.135 ± 0.864
1.513CysSer: 1.513 ± 0.891
0.757CysThr: 0.757 ± 1.062
0.757CysVal: 0.757 ± 1.11
0.0CysTrp: 0.0 ± 0.0
1.513CysTyr: 1.513 ± 1.037
0.0CysXaa: 0.0 ± 0.0
Asp
3.784AspAla: 3.784 ± 1.003
2.27AspCys: 2.27 ± 1.107
5.297AspAsp: 5.297 ± 1.666
5.297AspGlu: 5.297 ± 1.558
2.649AspPhe: 2.649 ± 1.362
3.027AspGly: 3.027 ± 0.87
2.27AspHis: 2.27 ± 0.988
3.405AspIle: 3.405 ± 0.761
4.54AspLys: 4.54 ± 2.247
6.054AspLeu: 6.054 ± 1.256
1.892AspMet: 1.892 ± 0.49
2.27AspAsn: 2.27 ± 0.879
3.027AspPro: 3.027 ± 0.868
2.649AspGln: 2.649 ± 1.189
1.892AspArg: 1.892 ± 0.853
2.649AspSer: 2.649 ± 1.189
3.784AspThr: 3.784 ± 1.111
3.784AspVal: 3.784 ± 0.593
0.757AspTrp: 0.757 ± 0.438
3.784AspTyr: 3.784 ± 1.291
0.0AspXaa: 0.0 ± 0.0
Glu
3.784GluAla: 3.784 ± 1.819
0.757GluCys: 0.757 ± 0.438
3.027GluAsp: 3.027 ± 1.396
3.405GluGlu: 3.405 ± 1.971
2.649GluPhe: 2.649 ± 1.502
2.649GluGly: 2.649 ± 1.154
1.892GluHis: 1.892 ± 0.795
1.892GluIle: 1.892 ± 0.714
3.784GluLys: 3.784 ± 2.19
6.054GluLeu: 6.054 ± 1.873
1.135GluMet: 1.135 ± 0.864
2.649GluAsn: 2.649 ± 1.154
4.919GluPro: 4.919 ± 1.212
2.649GluGln: 2.649 ± 1.516
3.784GluArg: 3.784 ± 1.232
3.027GluSer: 3.027 ± 0.906
4.54GluThr: 4.54 ± 1.285
1.892GluVal: 1.892 ± 1.268
0.378GluTrp: 0.378 ± 0.468
1.892GluTyr: 1.892 ± 0.753
0.0GluXaa: 0.0 ± 0.0
Phe
2.649PheAla: 2.649 ± 0.864
1.135PheCys: 1.135 ± 1.112
3.027PheAsp: 3.027 ± 0.788
3.405PheGlu: 3.405 ± 0.513
1.513PhePhe: 1.513 ± 1.009
1.513PheGly: 1.513 ± 0.491
0.757PheHis: 0.757 ± 0.422
2.27PheIle: 2.27 ± 0.724
2.649PheLys: 2.649 ± 1.088
2.27PheLeu: 2.27 ± 0.991
1.513PheMet: 1.513 ± 0.654
1.892PheAsn: 1.892 ± 1.029
1.513PhePro: 1.513 ± 0.876
3.027PheGln: 3.027 ± 1.967
1.135PheArg: 1.135 ± 0.657
3.027PheSer: 3.027 ± 1.589
0.757PheThr: 0.757 ± 0.438
3.027PheVal: 3.027 ± 1.774
0.0PheTrp: 0.0 ± 0.0
1.892PheTyr: 1.892 ± 0.714
0.0PheXaa: 0.0 ± 0.0
Gly
3.405GlyAla: 3.405 ± 0.816
0.757GlyCys: 0.757 ± 0.438
5.297GlyAsp: 5.297 ± 1.877
1.513GlyGlu: 1.513 ± 0.876
1.892GlyPhe: 1.892 ± 1.965
4.162GlyGly: 4.162 ± 2.809
1.513GlyHis: 1.513 ± 0.929
2.649GlyIle: 2.649 ± 0.864
3.405GlyLys: 3.405 ± 0.539
3.027GlyLeu: 3.027 ± 1.241
1.513GlyMet: 1.513 ± 1.037
1.135GlyAsn: 1.135 ± 0.907
3.405GlyPro: 3.405 ± 0.816
3.027GlyGln: 3.027 ± 1.269
3.027GlyArg: 3.027 ± 0.746
2.27GlySer: 2.27 ± 1.47
2.649GlyThr: 2.649 ± 0.742
1.513GlyVal: 1.513 ± 0.929
1.135GlyTrp: 1.135 ± 0.657
2.27GlyTyr: 2.27 ± 0.755
0.0GlyXaa: 0.0 ± 0.0
His
3.027HisAla: 3.027 ± 1.241
0.378HisCys: 0.378 ± 0.219
0.378HisAsp: 0.378 ± 0.63
2.649HisGlu: 2.649 ± 0.871
2.649HisPhe: 2.649 ± 0.796
3.405HisGly: 3.405 ± 1.764
0.378HisHis: 0.378 ± 0.219
2.27HisIle: 2.27 ± 1.727
0.378HisLys: 0.378 ± 0.468
3.405HisLeu: 3.405 ± 1.923
0.757HisMet: 0.757 ± 0.658
2.27HisAsn: 2.27 ± 1.058
1.135HisPro: 1.135 ± 1.147
2.27HisGln: 2.27 ± 0.967
1.892HisArg: 1.892 ± 0.767
2.649HisSer: 2.649 ± 0.801
0.757HisThr: 0.757 ± 0.438
1.892HisVal: 1.892 ± 0.824
0.0HisTrp: 0.0 ± 0.0
0.757HisTyr: 0.757 ± 1.143
0.0HisXaa: 0.0 ± 0.0
Ile
2.649IleAla: 2.649 ± 1.11
0.378IleCys: 0.378 ± 0.219
1.892IleAsp: 1.892 ± 0.795
2.649IleGlu: 2.649 ± 0.858
2.27IlePhe: 2.27 ± 0.968
1.513IleGly: 1.513 ± 0.655
2.27IleHis: 2.27 ± 1.322
1.135IleIle: 1.135 ± 0.483
3.027IleLys: 3.027 ± 1.241
3.784IleLeu: 3.784 ± 2.941
0.757IleMet: 0.757 ± 0.438
1.135IleAsn: 1.135 ± 0.483
2.649IlePro: 2.649 ± 0.698
1.892IleGln: 1.892 ± 0.795
3.027IleArg: 3.027 ± 0.637
2.27IleSer: 2.27 ± 1.314
5.675IleThr: 5.675 ± 1.954
4.54IleVal: 4.54 ± 1.01
0.0IleTrp: 0.0 ± 0.0
2.27IleTyr: 2.27 ± 1.526
0.0IleXaa: 0.0 ± 0.0
Lys
5.675LysAla: 5.675 ± 1.466
0.378LysCys: 0.378 ± 0.63
3.405LysAsp: 3.405 ± 1.163
1.513LysGlu: 1.513 ± 0.658
1.892LysPhe: 1.892 ± 0.714
1.513LysGly: 1.513 ± 0.491
1.135LysHis: 1.135 ± 0.657
4.162LysIle: 4.162 ± 1.78
2.649LysLys: 2.649 ± 1.088
6.054LysLeu: 6.054 ± 1.981
0.378LysMet: 0.378 ± 0.611
0.757LysAsn: 0.757 ± 0.438
4.919LysPro: 4.919 ± 1.472
1.513LysGln: 1.513 ± 0.813
4.54LysArg: 4.54 ± 1.45
3.027LysSer: 3.027 ± 1.885
2.649LysThr: 2.649 ± 1.064
4.162LysVal: 4.162 ± 1.293
0.378LysTrp: 0.378 ± 0.219
1.135LysTyr: 1.135 ± 0.657
0.0LysXaa: 0.0 ± 0.0
Leu
8.324LeuAla: 8.324 ± 3.076
2.27LeuCys: 2.27 ± 1.292
6.432LeuAsp: 6.432 ± 2.503
5.297LeuGlu: 5.297 ± 1.627
5.675LeuPhe: 5.675 ± 1.603
4.54LeuGly: 4.54 ± 2.35
4.162LeuHis: 4.162 ± 2.268
5.675LeuIle: 5.675 ± 1.087
3.784LeuLys: 3.784 ± 1.061
10.594LeuLeu: 10.594 ± 2.052
1.513LeuMet: 1.513 ± 0.713
2.649LeuAsn: 2.649 ± 1.153
7.189LeuPro: 7.189 ± 1.427
3.784LeuGln: 3.784 ± 1.404
5.297LeuArg: 5.297 ± 1.43
7.567LeuSer: 7.567 ± 1.747
7.567LeuThr: 7.567 ± 1.877
5.297LeuVal: 5.297 ± 1.833
0.757LeuTrp: 0.757 ± 0.438
2.649LeuTyr: 2.649 ± 1.211
0.0LeuXaa: 0.0 ± 0.0
Met
0.757MetAla: 0.757 ± 0.438
0.378MetCys: 0.378 ± 0.219
0.757MetAsp: 0.757 ± 0.422
1.135MetGlu: 1.135 ± 0.657
0.0MetPhe: 0.0 ± 0.0
0.378MetGly: 0.378 ± 0.219
0.757MetHis: 0.757 ± 0.559
0.378MetIle: 0.378 ± 0.611
0.378MetLys: 0.378 ± 0.769
1.135MetLeu: 1.135 ± 1.061
0.0MetMet: 0.0 ± 0.0
1.513MetAsn: 1.513 ± 1.037
1.513MetPro: 1.513 ± 1.037
1.135MetGln: 1.135 ± 0.657
1.135MetArg: 1.135 ± 0.581
1.513MetSer: 1.513 ± 0.813
1.513MetThr: 1.513 ± 0.876
1.135MetVal: 1.135 ± 1.061
0.0MetTrp: 0.0 ± 0.0
0.378MetTyr: 0.378 ± 0.219
0.0MetXaa: 0.0 ± 0.0
Asn
6.054AsnAla: 6.054 ± 1.531
1.135AsnCys: 1.135 ± 0.657
2.649AsnAsp: 2.649 ± 0.661
2.27AsnGlu: 2.27 ± 1.02
2.27AsnPhe: 2.27 ± 0.755
1.135AsnGly: 1.135 ± 0.51
1.135AsnHis: 1.135 ± 1.249
2.649AsnIle: 2.649 ± 0.698
1.513AsnLys: 1.513 ± 0.923
4.54AsnLeu: 4.54 ± 1.215
0.378AsnMet: 0.378 ± 0.611
1.513AsnAsn: 1.513 ± 0.876
3.027AsnPro: 3.027 ± 0.906
1.513AsnGln: 1.513 ± 1.027
2.649AsnArg: 2.649 ± 1.513
2.649AsnSer: 2.649 ± 1.38
3.027AsnThr: 3.027 ± 0.767
3.405AsnVal: 3.405 ± 0.539
0.0AsnTrp: 0.0 ± 0.0
1.135AsnTyr: 1.135 ± 0.657
0.0AsnXaa: 0.0 ± 0.0
Pro
4.54ProAla: 4.54 ± 1.674
0.757ProCys: 0.757 ± 0.729
4.162ProAsp: 4.162 ± 1.636
4.162ProGlu: 4.162 ± 1.847
1.892ProPhe: 1.892 ± 1.445
3.405ProGly: 3.405 ± 2.23
3.784ProHis: 3.784 ± 2.257
3.405ProIle: 3.405 ± 1.227
2.649ProLys: 2.649 ± 1.362
6.054ProLeu: 6.054 ± 0.6
0.757ProMet: 0.757 ± 0.729
3.405ProAsn: 3.405 ± 1.535
7.189ProPro: 7.189 ± 3.611
3.027ProGln: 3.027 ± 0.868
1.892ProArg: 1.892 ± 0.77
4.162ProSer: 4.162 ± 0.821
4.162ProThr: 4.162 ± 0.869
4.162ProVal: 4.162 ± 1.464
0.378ProTrp: 0.378 ± 0.219
1.513ProTyr: 1.513 ± 0.655
0.0ProXaa: 0.0 ± 0.0
Gln
2.649GlnAla: 2.649 ± 0.759
0.757GlnCys: 0.757 ± 0.438
3.405GlnAsp: 3.405 ± 1.307
1.513GlnGlu: 1.513 ± 0.876
0.757GlnPhe: 0.757 ± 0.518
3.405GlnGly: 3.405 ± 2.419
1.513GlnHis: 1.513 ± 1.214
3.027GlnIle: 3.027 ± 1.379
1.892GlnLys: 1.892 ± 0.714
6.81GlnLeu: 6.81 ± 1.459
0.0GlnMet: 0.0 ± 0.0
1.892GlnAsn: 1.892 ± 0.639
3.405GlnPro: 3.405 ± 1.002
3.405GlnGln: 3.405 ± 1.53
2.27GlnArg: 2.27 ± 0.967
3.784GlnSer: 3.784 ± 0.689
3.784GlnThr: 3.784 ± 1.082
2.27GlnVal: 2.27 ± 0.895
0.378GlnTrp: 0.378 ± 0.219
1.135GlnTyr: 1.135 ± 0.657
0.0GlnXaa: 0.0 ± 0.0
Arg
6.054ArgAla: 6.054 ± 1.989
1.892ArgCys: 1.892 ± 2.286
4.162ArgAsp: 4.162 ± 1.183
5.297ArgGlu: 5.297 ± 1.723
2.27ArgPhe: 2.27 ± 0.917
1.135ArgGly: 1.135 ± 0.51
0.757ArgHis: 0.757 ± 0.438
1.892ArgIle: 1.892 ± 0.853
2.27ArgLys: 2.27 ± 0.9
6.81ArgLeu: 6.81 ± 2.004
0.378ArgMet: 0.378 ± 0.7
1.135ArgAsn: 1.135 ± 0.657
4.54ArgPro: 4.54 ± 1.156
3.405ArgGln: 3.405 ± 1.06
5.675ArgArg: 5.675 ± 2.159
3.405ArgSer: 3.405 ± 0.874
3.027ArgThr: 3.027 ± 1.351
2.649ArgVal: 2.649 ± 1.927
0.378ArgTrp: 0.378 ± 0.219
1.513ArgTyr: 1.513 ± 1.128
0.0ArgXaa: 0.0 ± 0.0
Ser
3.405SerAla: 3.405 ± 1.516
0.757SerCys: 0.757 ± 0.988
6.81SerAsp: 6.81 ± 1.186
3.405SerGlu: 3.405 ± 0.59
1.135SerPhe: 1.135 ± 1.505
3.405SerGly: 3.405 ± 0.788
1.135SerHis: 1.135 ± 1.42
1.892SerIle: 1.892 ± 0.714
1.892SerLys: 1.892 ± 1.599
6.81SerLeu: 6.81 ± 1.571
0.378SerMet: 0.378 ± 0.611
4.162SerAsn: 4.162 ± 1.354
4.162SerPro: 4.162 ± 1.208
3.405SerGln: 3.405 ± 1.203
4.54SerArg: 4.54 ± 3.322
5.297SerSer: 5.297 ± 2.245
6.054SerThr: 6.054 ± 1.836
1.892SerVal: 1.892 ± 0.753
1.135SerTrp: 1.135 ± 0.581
1.892SerTyr: 1.892 ± 0.639
0.0SerXaa: 0.0 ± 0.0
Thr
3.784ThrAla: 3.784 ± 1.762
0.757ThrCys: 0.757 ± 0.518
3.405ThrAsp: 3.405 ± 1.912
3.027ThrGlu: 3.027 ± 1.235
2.649ThrPhe: 2.649 ± 0.759
4.162ThrGly: 4.162 ± 0.618
3.405ThrHis: 3.405 ± 0.803
3.405ThrIle: 3.405 ± 0.936
3.027ThrLys: 3.027 ± 0.868
8.702ThrLeu: 8.702 ± 2.715
0.757ThrMet: 0.757 ± 0.422
5.675ThrAsn: 5.675 ± 1.796
3.027ThrPro: 3.027 ± 0.599
3.405ThrGln: 3.405 ± 1.491
5.297ThrArg: 5.297 ± 1.613
5.297ThrSer: 5.297 ± 0.933
7.567ThrThr: 7.567 ± 2.54
4.162ThrVal: 4.162 ± 0.6
0.0ThrTrp: 0.0 ± 0.0
1.135ThrTyr: 1.135 ± 0.657
0.0ThrXaa: 0.0 ± 0.0
Val
2.27ValAla: 2.27 ± 0.769
1.135ValCys: 1.135 ± 1.42
3.405ValAsp: 3.405 ± 1.244
4.162ValGlu: 4.162 ± 1.337
1.892ValPhe: 1.892 ± 0.898
1.892ValGly: 1.892 ± 0.826
0.757ValHis: 0.757 ± 0.438
2.649ValIle: 2.649 ± 0.573
3.784ValLys: 3.784 ± 1.507
5.297ValLeu: 5.297 ± 0.634
1.135ValMet: 1.135 ± 0.657
4.54ValAsn: 4.54 ± 1.064
3.784ValPro: 3.784 ± 2.263
2.27ValGln: 2.27 ± 1.245
3.027ValArg: 3.027 ± 1.115
4.162ValSer: 4.162 ± 1.602
6.054ValThr: 6.054 ± 1.974
1.513ValVal: 1.513 ± 0.655
0.378ValTrp: 0.378 ± 0.219
1.892ValTyr: 1.892 ± 1.502
0.0ValXaa: 0.0 ± 0.0
Trp
0.378TrpAla: 0.378 ± 0.219
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.378TrpPhe: 0.378 ± 0.219
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.757TrpLys: 0.757 ± 0.438
0.757TrpLeu: 0.757 ± 0.422
0.0TrpMet: 0.0 ± 0.0
0.378TrpAsn: 0.378 ± 0.219
0.378TrpPro: 0.378 ± 0.219
0.378TrpGln: 0.378 ± 0.468
0.378TrpArg: 0.378 ± 0.219
1.135TrpSer: 1.135 ± 0.51
0.757TrpThr: 0.757 ± 0.518
1.135TrpVal: 1.135 ± 0.657
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.162TyrAla: 4.162 ± 1.117
1.513TyrCys: 1.513 ± 0.775
3.405TyrAsp: 3.405 ± 0.874
1.513TyrGlu: 1.513 ± 0.655
0.378TyrPhe: 0.378 ± 0.219
1.892TyrGly: 1.892 ± 0.54
1.513TyrHis: 1.513 ± 0.787
1.513TyrIle: 1.513 ± 1.252
1.513TyrLys: 1.513 ± 0.826
3.027TyrLeu: 3.027 ± 1.396
0.0TyrMet: 0.0 ± 0.0
0.378TyrAsn: 0.378 ± 0.63
1.135TyrPro: 1.135 ± 0.657
2.27TyrGln: 2.27 ± 0.558
2.27TyrArg: 2.27 ± 0.641
1.513TyrSer: 1.513 ± 1.08
1.892TyrThr: 1.892 ± 0.884
2.649TyrVal: 2.649 ± 0.725
0.0TyrTrp: 0.0 ± 0.0
1.135TyrTyr: 1.135 ± 0.717
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2644 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski