Amino acid dipepetide frequency for Falsochrobactrum ovis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.665AlaAla: 12.665 ± 0.163	0.888AlaCys: 0.888 ± 0.031	6.014AlaAsp: 6.014 ± 0.139	7.009AlaGlu: 7.009 ± 0.105	4.201AlaPhe: 4.201 ± 0.069	8.539AlaGly: 8.539 ± 0.106	2.005AlaHis: 2.005 ± 0.046	7.139AlaIle: 7.139 ± 0.089	4.505AlaLys: 4.505 ± 0.08	11.459AlaLeu: 11.459 ± 0.125	3.036AlaMet: 3.036 ± 0.06	3.347AlaAsn: 3.347 ± 0.065	4.295AlaPro: 4.295 ± 0.094	4.02AlaGln: 4.02 ± 0.066	6.629AlaArg: 6.629 ± 0.081	6.328AlaSer: 6.328 ± 0.089	5.129AlaThr: 5.129 ± 0.081	7.374AlaVal: 7.374 ± 0.1	1.169AlaTrp: 1.169 ± 0.038	2.521AlaTyr: 2.521 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.86CysAla: 0.86 ± 0.032	0.108CysCys: 0.108 ± 0.012	0.498CysAsp: 0.498 ± 0.023	0.435CysGlu: 0.435 ± 0.023	0.368CysPhe: 0.368 ± 0.02	0.783CysGly: 0.783 ± 0.029	0.227CysHis: 0.227 ± 0.018	0.448CysIle: 0.448 ± 0.023	0.247CysLys: 0.247 ± 0.017	0.733CysLeu: 0.733 ± 0.029	0.176CysMet: 0.176 ± 0.014	0.256CysAsn: 0.256 ± 0.019	0.402CysPro: 0.402 ± 0.021	0.238CysGln: 0.238 ± 0.017	0.5CysArg: 0.5 ± 0.025	0.471CysSer: 0.471 ± 0.024	0.384CysThr: 0.384 ± 0.02	0.558CysVal: 0.558 ± 0.029	0.114CysTrp: 0.114 ± 0.012	0.189CysTyr: 0.189 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.077AspAla: 6.077 ± 0.128	0.49AspCys: 0.49 ± 0.024	3.064AspAsp: 3.064 ± 0.065	3.911AspGlu: 3.911 ± 0.076	2.233AspPhe: 2.233 ± 0.047	4.569AspGly: 4.569 ± 0.087	1.257AspHis: 1.257 ± 0.038	3.7AspIle: 3.7 ± 0.058	2.173AspLys: 2.173 ± 0.052	5.425AspLeu: 5.425 ± 0.09	1.433AspMet: 1.433 ± 0.041	1.785AspAsn: 1.785 ± 0.045	3.03AspPro: 3.03 ± 0.058	1.949AspGln: 1.949 ± 0.039	3.749AspArg: 3.749 ± 0.066	2.319AspSer: 2.319 ± 0.051	2.41AspThr: 2.41 ± 0.057	3.758AspVal: 3.758 ± 0.068	0.869AspTrp: 0.869 ± 0.032	1.659AspTyr: 1.659 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	7.057GluAla: 7.057 ± 0.098	0.378GluCys: 0.378 ± 0.022	2.968GluAsp: 2.968 ± 0.058	3.89GluGlu: 3.89 ± 0.084	2.071GluPhe: 2.071 ± 0.046	4.239GluGly: 4.239 ± 0.079	1.235GluHis: 1.235 ± 0.037	4.339GluIle: 4.339 ± 0.062	3.444GluLys: 3.444 ± 0.069	5.86GluLeu: 5.86 ± 0.078	1.688GluMet: 1.688 ± 0.045	2.512GluAsn: 2.512 ± 0.052	2.694GluPro: 2.694 ± 0.061	2.48GluGln: 2.48 ± 0.048	4.616GluArg: 4.616 ± 0.089	2.536GluSer: 2.536 ± 0.053	3.641GluThr: 3.641 ± 0.068	3.833GluVal: 3.833 ± 0.068	0.745GluTrp: 0.745 ± 0.028	1.293GluTyr: 1.293 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	4.213PheAla: 4.213 ± 0.069	0.4PheCys: 0.4 ± 0.019	2.798PheAsp: 2.798 ± 0.056	2.352PheGlu: 2.352 ± 0.052	1.656PhePhe: 1.656 ± 0.054	3.646PheGly: 3.646 ± 0.073	0.793PheHis: 0.793 ± 0.029	2.35PheIle: 2.35 ± 0.053	1.303PheLys: 1.303 ± 0.04	3.628PheLeu: 3.628 ± 0.073	0.95PheMet: 0.95 ± 0.033	1.47PheAsn: 1.47 ± 0.039	1.609PhePro: 1.609 ± 0.037	1.135PheGln: 1.135 ± 0.036	2.242PheArg: 2.242 ± 0.052	2.785PheSer: 2.785 ± 0.058	2.063PheThr: 2.063 ± 0.041	2.752PheVal: 2.752 ± 0.05	0.555PheTrp: 0.555 ± 0.026	1.063PheTyr: 1.063 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	7.582GlyAla: 7.582 ± 0.121	0.726GlyCys: 0.726 ± 0.031	3.985GlyAsp: 3.985 ± 0.082	4.713GlyGlu: 4.713 ± 0.075	3.611GlyPhe: 3.611 ± 0.075	6.495GlyGly: 6.495 ± 0.136	1.666GlyHis: 1.666 ± 0.041	5.288GlyIle: 5.288 ± 0.084	4.011GlyLys: 4.011 ± 0.076	8.132GlyLeu: 8.132 ± 0.109	2.153GlyMet: 2.153 ± 0.048	2.593GlyAsn: 2.593 ± 0.073	2.805GlyPro: 2.805 ± 0.059	2.685GlyGln: 2.685 ± 0.062	4.963GlyArg: 4.963 ± 0.068	4.701GlySer: 4.701 ± 0.085	4.272GlyThr: 4.272 ± 0.08	5.697GlyVal: 5.697 ± 0.08	1.204GlyTrp: 1.204 ± 0.039	2.249GlyTyr: 2.249 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.934HisAla: 1.934 ± 0.047	0.217HisCys: 0.217 ± 0.016	1.186HisAsp: 1.186 ± 0.039	1.108HisGlu: 1.108 ± 0.034	0.871HisPhe: 0.871 ± 0.028	1.768HisGly: 1.768 ± 0.046	0.527HisHis: 0.527 ± 0.029	1.266HisIle: 1.266 ± 0.036	0.702HisLys: 0.702 ± 0.026	1.969HisLeu: 1.969 ± 0.05	0.549HisMet: 0.549 ± 0.022	0.681HisAsn: 0.681 ± 0.03	1.172HisPro: 1.172 ± 0.037	0.669HisGln: 0.669 ± 0.029	1.303HisArg: 1.303 ± 0.036	1.13HisSer: 1.13 ± 0.034	0.792HisThr: 0.792 ± 0.029	1.324HisVal: 1.324 ± 0.038	0.316HisTrp: 0.316 ± 0.017	0.628HisTyr: 0.628 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	7.983IleAla: 7.983 ± 0.096	0.633IleCys: 0.633 ± 0.029	4.177IleAsp: 4.177 ± 0.068	4.458IleGlu: 4.458 ± 0.076	2.46IlePhe: 2.46 ± 0.059	5.592IleGly: 5.592 ± 0.094	1.094IleHis: 1.094 ± 0.031	3.951IleIle: 3.951 ± 0.078	2.315IleLys: 2.315 ± 0.05	5.661IleLeu: 5.661 ± 0.098	1.419IleMet: 1.419 ± 0.037	2.23IleAsn: 2.23 ± 0.053	2.746IlePro: 2.746 ± 0.062	1.517IleGln: 1.517 ± 0.039	3.704IleArg: 3.704 ± 0.069	4.255IleSer: 4.255 ± 0.077	3.229IleThr: 3.229 ± 0.069	4.63IleVal: 4.63 ± 0.064	0.712IleTrp: 0.712 ± 0.033	1.59IleTyr: 1.59 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	4.638LysAla: 4.638 ± 0.079	0.203LysCys: 0.203 ± 0.014	2.141LysAsp: 2.141 ± 0.052	2.301LysGlu: 2.301 ± 0.054	1.245LysPhe: 1.245 ± 0.042	2.961LysGly: 2.961 ± 0.06	0.819LysHis: 0.819 ± 0.031	2.643LysIle: 2.643 ± 0.056	1.991LysLys: 1.991 ± 0.053	4.386LysLeu: 4.386 ± 0.076	1.0LysMet: 1.0 ± 0.032	1.577LysAsn: 1.577 ± 0.04	2.452LysPro: 2.452 ± 0.058	1.47LysGln: 1.47 ± 0.04	2.939LysArg: 2.939 ± 0.059	2.611LysSer: 2.611 ± 0.052	2.472LysThr: 2.472 ± 0.048	2.713LysVal: 2.713 ± 0.062	0.443LysTrp: 0.443 ± 0.022	0.905LysTyr: 0.905 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	11.285LeuAla: 11.285 ± 0.12	0.857LeuCys: 0.857 ± 0.03	5.678LeuAsp: 5.678 ± 0.084	5.748LeuGlu: 5.748 ± 0.079	3.823LeuPhe: 3.823 ± 0.07	7.591LeuGly: 7.591 ± 0.104	1.822LeuHis: 1.822 ± 0.043	6.29LeuIle: 6.29 ± 0.095	4.336LeuLys: 4.336 ± 0.074	9.139LeuLeu: 9.139 ± 0.138	2.468LeuMet: 2.468 ± 0.053	3.232LeuAsn: 3.232 ± 0.069	5.012LeuPro: 5.012 ± 0.086	2.981LeuGln: 2.981 ± 0.053	5.996LeuArg: 5.996 ± 0.093	6.929LeuSer: 6.929 ± 0.085	5.375LeuThr: 5.375 ± 0.078	6.548LeuVal: 6.548 ± 0.088	0.989LeuTrp: 0.989 ± 0.036	2.285LeuTyr: 2.285 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.794MetAla: 2.794 ± 0.053	0.15MetCys: 0.15 ± 0.012	1.131MetAsp: 1.131 ± 0.035	1.274MetGlu: 1.274 ± 0.032	0.764MetPhe: 0.764 ± 0.032	1.831MetGly: 1.831 ± 0.045	0.469MetHis: 0.469 ± 0.022	1.631MetIle: 1.631 ± 0.039	1.184MetLys: 1.184 ± 0.039	2.57MetLeu: 2.57 ± 0.057	0.691MetMet: 0.691 ± 0.028	1.031MetAsn: 1.031 ± 0.037	1.417MetPro: 1.417 ± 0.038	1.03MetGln: 1.03 ± 0.036	1.886MetArg: 1.886 ± 0.043	1.777MetSer: 1.777 ± 0.044	1.685MetThr: 1.685 ± 0.04	1.688MetVal: 1.688 ± 0.043	0.238MetTrp: 0.238 ± 0.018	0.29MetTyr: 0.29 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.642AsnAla: 3.642 ± 0.075	0.284AsnCys: 0.284 ± 0.02	1.776AsnAsp: 1.776 ± 0.046	1.886AsnGlu: 1.886 ± 0.043	1.342AsnPhe: 1.342 ± 0.037	2.962AsnGly: 2.962 ± 0.065	0.707AsnHis: 0.707 ± 0.031	2.307AsnIle: 2.307 ± 0.049	1.208AsnLys: 1.208 ± 0.04	3.196AsnLeu: 3.196 ± 0.071	0.908AsnMet: 0.908 ± 0.027	1.235AsnAsn: 1.235 ± 0.04	2.221AsnPro: 2.221 ± 0.049	1.144AsnGln: 1.144 ± 0.036	2.133AsnArg: 2.133 ± 0.047	1.963AsnSer: 1.963 ± 0.048	1.596AsnThr: 1.596 ± 0.042	2.301AsnVal: 2.301 ± 0.056	0.556AsnTrp: 0.556 ± 0.025	0.961AsnTyr: 0.961 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	4.798ProAla: 4.798 ± 0.085	0.269ProCys: 0.269 ± 0.017	3.259ProAsp: 3.259 ± 0.056	3.49ProGlu: 3.49 ± 0.056	1.951ProPhe: 1.951 ± 0.041	3.418ProGly: 3.418 ± 0.059	1.14ProHis: 1.14 ± 0.035	2.727ProIle: 2.727 ± 0.056	1.798ProLys: 1.798 ± 0.046	4.363ProLeu: 4.363 ± 0.07	1.068ProMet: 1.068 ± 0.035	1.666ProAsn: 1.666 ± 0.043	1.807ProPro: 1.807 ± 0.057	1.841ProGln: 1.841 ± 0.056	2.423ProArg: 2.423 ± 0.051	2.731ProSer: 2.731 ± 0.055	2.345ProThr: 2.345 ± 0.051	3.812ProVal: 3.812 ± 0.068	0.605ProTrp: 0.605 ± 0.026	1.266ProTyr: 1.266 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.869GlnAla: 3.869 ± 0.07	0.215GlnCys: 0.215 ± 0.015	1.533GlnAsp: 1.533 ± 0.043	1.928GlnGlu: 1.928 ± 0.048	1.247GlnPhe: 1.247 ± 0.035	2.362GlnGly: 2.362 ± 0.053	0.673GlnHis: 0.673 ± 0.029	2.322GlnIle: 2.322 ± 0.044	1.632GlnLys: 1.632 ± 0.043	3.379GlnLeu: 3.379 ± 0.059	1.005GlnMet: 1.005 ± 0.039	1.333GlnAsn: 1.333 ± 0.037	1.656GlnPro: 1.656 ± 0.049	1.408GlnGln: 1.408 ± 0.053	2.483GlnArg: 2.483 ± 0.055	2.23GlnSer: 2.23 ± 0.049	1.835GlnThr: 1.835 ± 0.047	2.114GlnVal: 2.114 ± 0.049	0.412GlnTrp: 0.412 ± 0.019	0.79GlnTyr: 0.79 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	6.107ArgAla: 6.107 ± 0.09	0.411ArgCys: 0.411 ± 0.024	3.519ArgAsp: 3.519 ± 0.061	4.114ArgGlu: 4.114 ± 0.076	2.868ArgPhe: 2.868 ± 0.062	4.191ArgGly: 4.191 ± 0.068	1.383ArgHis: 1.383 ± 0.04	4.279ArgIle: 4.279 ± 0.075	2.762ArgLys: 2.762 ± 0.057	6.633ArgLeu: 6.633 ± 0.094	1.731ArgMet: 1.731 ± 0.039	2.238ArgAsn: 2.238 ± 0.053	2.838ArgPro: 2.838 ± 0.058	2.558ArgGln: 2.558 ± 0.058	4.504ArgArg: 4.504 ± 0.083	3.605ArgSer: 3.605 ± 0.065	2.919ArgThr: 2.919 ± 0.053	4.126ArgVal: 4.126 ± 0.08	0.827ArgTrp: 0.827 ± 0.031	1.691ArgTyr: 1.691 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.339SerAla: 6.339 ± 0.081	0.438SerCys: 0.438 ± 0.022	3.352SerAsp: 3.352 ± 0.067	3.451SerGlu: 3.451 ± 0.071	2.744SerPhe: 2.744 ± 0.06	5.808SerGly: 5.808 ± 0.097	1.171SerHis: 1.171 ± 0.038	3.629SerIle: 3.629 ± 0.068	2.24SerLys: 2.24 ± 0.045	5.816SerLeu: 5.816 ± 0.094	1.445SerMet: 1.445 ± 0.04	1.909SerAsn: 1.909 ± 0.048	2.66SerPro: 2.66 ± 0.059	2.076SerGln: 2.076 ± 0.05	3.603SerArg: 3.603 ± 0.068	3.66SerSer: 3.66 ± 0.07	2.955SerThr: 2.955 ± 0.069	4.272SerVal: 4.272 ± 0.07	0.805SerTrp: 0.805 ± 0.028	1.487SerTyr: 1.487 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	5.401ThrAla: 5.401 ± 0.08	0.384ThrCys: 0.384 ± 0.021	2.796ThrAsp: 2.796 ± 0.059	2.78ThrGlu: 2.78 ± 0.054	1.921ThrPhe: 1.921 ± 0.042	4.693ThrGly: 4.693 ± 0.075	1.028ThrHis: 1.028 ± 0.031	3.613ThrIle: 3.613 ± 0.057	1.885ThrLys: 1.885 ± 0.046	5.339ThrLeu: 5.339 ± 0.083	1.203ThrMet: 1.203 ± 0.034	1.657ThrAsn: 1.657 ± 0.043	2.985ThrPro: 2.985 ± 0.052	1.602ThrGln: 1.602 ± 0.039	2.856ThrArg: 2.856 ± 0.054	3.046ThrSer: 3.046 ± 0.064	2.754ThrThr: 2.754 ± 0.064	4.009ThrVal: 4.009 ± 0.075	0.524ThrTrp: 0.524 ± 0.022	1.301ThrTyr: 1.301 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	7.553ValAla: 7.553 ± 0.092	0.55ValCys: 0.55 ± 0.024	3.838ValAsp: 3.838 ± 0.065	4.682ValGlu: 4.682 ± 0.08	2.761ValPhe: 2.761 ± 0.049	5.103ValGly: 5.103 ± 0.082	1.283ValHis: 1.283 ± 0.042	4.453ValIle: 4.453 ± 0.083	2.728ValLys: 2.728 ± 0.055	6.743ValLeu: 6.743 ± 0.101	1.725ValMet: 1.725 ± 0.05	2.254ValAsn: 2.254 ± 0.055	3.224ValPro: 3.224 ± 0.059	2.099ValGln: 2.099 ± 0.048	4.096ValArg: 4.096 ± 0.062	4.514ValSer: 4.514 ± 0.072	4.065ValThr: 4.065 ± 0.073	5.167ValVal: 5.167 ± 0.094	0.78ValTrp: 0.78 ± 0.029	1.507ValTyr: 1.507 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.055TrpAla: 1.055 ± 0.037	0.128TrpCys: 0.128 ± 0.012	0.619TrpAsp: 0.619 ± 0.027	0.556TrpGlu: 0.556 ± 0.024	0.522TrpPhe: 0.522 ± 0.023	0.826TrpGly: 0.826 ± 0.03	0.311TrpHis: 0.311 ± 0.019	0.657TrpIle: 0.657 ± 0.026	0.552TrpLys: 0.552 ± 0.026	1.567TrpLeu: 1.567 ± 0.046	0.344TrpMet: 0.344 ± 0.021	0.494TrpAsn: 0.494 ± 0.022	0.628TrpPro: 0.628 ± 0.026	0.592TrpGln: 0.592 ± 0.027	0.96TrpArg: 0.96 ± 0.031	0.759TrpSer: 0.759 ± 0.031	0.633TrpThr: 0.633 ± 0.026	0.781TrpVal: 0.781 ± 0.03	0.224TrpTrp: 0.224 ± 0.017	0.277TrpTyr: 0.277 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.418TyrAla: 2.418 ± 0.05	0.264TyrCys: 0.264 ± 0.016	1.529TyrAsp: 1.529 ± 0.048	1.433TyrGlu: 1.433 ± 0.04	1.104TyrPhe: 1.104 ± 0.034	2.154TyrGly: 2.154 ± 0.049	0.5TyrHis: 0.5 ± 0.023	1.326TyrIle: 1.326 ± 0.037	0.892TyrLys: 0.892 ± 0.032	2.389TyrLeu: 2.389 ± 0.053	0.54TyrMet: 0.54 ± 0.021	0.828TyrAsn: 0.828 ± 0.03	1.123TyrPro: 1.123 ± 0.034	0.932TyrGln: 0.932 ± 0.03	1.72TyrArg: 1.72 ± 0.041	1.509TyrSer: 1.509 ± 0.044	1.223TyrThr: 1.223 ± 0.043	1.67TyrVal: 1.67 ± 0.047	0.399TyrTrp: 0.399 ± 0.023	0.729TyrTyr: 0.729 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3123 proteins (950354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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