Human papillomavirus 167

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 21

Average proteome isoelectric point is 6.27

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|U6BRB0|U6BRB0_9PAPI Replication protein E1 OS=Human papillomavirus 167 OX=1420545 GN=E1 PE=3 SV=1
MM1 pKa = 7.68RR2 pKa = 11.84GDD4 pKa = 3.9RR5 pKa = 11.84PTLGDD10 pKa = 4.05IILEE14 pKa = 3.97EE15 pKa = 5.18LIMPINLLCDD25 pKa = 3.51EE26 pKa = 4.89ASEE29 pKa = 4.58SLSSDD34 pKa = 3.48CEE36 pKa = 4.4GEE38 pKa = 4.17EE39 pKa = 4.27EE40 pKa = 4.03QLEE43 pKa = 4.61PYY45 pKa = 10.18RR46 pKa = 11.84IEE48 pKa = 4.22CTCFNCGIRR57 pKa = 11.84IRR59 pKa = 11.84FCVVCSRR66 pKa = 11.84GGIGAFEE73 pKa = 3.89QLLTEE78 pKa = 5.1EE79 pKa = 4.85INLICATCARR89 pKa = 11.84NLQHH93 pKa = 6.96GRR95 pKa = 11.84SQQ97 pKa = 3.11

Molecular weight: 10.84 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|U6BME7|U6BME7_9PAPI Major capsid protein L1 OS=Human papillomavirus 167 OX=1420545 GN=L1 PE=3 SV=1
MM1 pKa = 8.14DD2 pKa = 4.45ARR4 pKa = 11.84FPVNLFDD11 pKa = 3.53YY12 pKa = 10.38CSYY15 pKa = 11.34FEE17 pKa = 5.03IPFFNLKK24 pKa = 9.88LKK26 pKa = 10.93CIFCNFYY33 pKa = 9.91LTLTDD38 pKa = 5.57LADD41 pKa = 5.2FYY43 pKa = 11.62QKK45 pKa = 10.78DD46 pKa = 3.52LCLVWKK52 pKa = 9.68NKK54 pKa = 10.02CCFACCAKK62 pKa = 10.34CLRR65 pKa = 11.84LSAAYY70 pKa = 9.26EE71 pKa = 3.97YY72 pKa = 9.81NTYY75 pKa = 9.95FVCCVSGTTLEE86 pKa = 4.09FLQKK90 pKa = 10.55KK91 pKa = 9.04SLNEE95 pKa = 3.62IIIRR99 pKa = 11.84CSLCLRR105 pKa = 11.84KK106 pKa = 9.46LDD108 pKa = 3.82YY109 pKa = 10.98AEE111 pKa = 5.31KK112 pKa = 9.78IQHH115 pKa = 5.71SFNEE119 pKa = 4.32RR120 pKa = 11.84FCLVRR125 pKa = 11.84GHH127 pKa = 6.35WRR129 pKa = 11.84GCCRR133 pKa = 11.84FCSKK137 pKa = 10.84KK138 pKa = 10.19EE139 pKa = 3.77

Molecular weight: 16.56 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2259

97

604

376.5

42.97

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.401 ± 0.333

2.479 ± 1.122

6.596 ± 0.463

6.375 ± 0.697

5.356 ± 0.568

5.002 ± 0.564

2.125 ± 0.201

5.578 ± 0.569

5.533 ± 0.833

8.632 ± 0.626

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.417 ± 0.327

5.71 ± 0.688

5.533 ± 1.047

4.117 ± 0.596

5.755 ± 0.763

7.127 ± 0.738

6.242 ± 0.638

5.843 ± 0.635

1.195 ± 0.311

3.984 ± 0.309
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski