Amino acid dipepetide frequency for Acinetobacter bouvetii DSM 14964 = CIP 107468

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.937AlaAla: 9.937 ± 0.168	1.011AlaCys: 1.011 ± 0.034	5.169AlaAsp: 5.169 ± 0.086	6.507AlaGlu: 6.507 ± 0.118	3.693AlaPhe: 3.693 ± 0.069	6.939AlaGly: 6.939 ± 0.11	1.982AlaHis: 1.982 ± 0.051	5.842AlaIle: 5.842 ± 0.096	5.282AlaLys: 5.282 ± 0.089	10.63AlaLeu: 10.63 ± 0.113	2.736AlaMet: 2.736 ± 0.056	3.528AlaAsn: 3.528 ± 0.073	3.522AlaPro: 3.522 ± 0.081	5.236AlaGln: 5.236 ± 0.088	3.538AlaArg: 3.538 ± 0.063	5.591AlaSer: 5.591 ± 0.099	3.952AlaThr: 3.952 ± 0.077	7.108AlaVal: 7.108 ± 0.106	1.207AlaTrp: 1.207 ± 0.04	2.815AlaTyr: 2.815 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.847CysAla: 0.847 ± 0.032	0.161CysCys: 0.161 ± 0.014	0.489CysAsp: 0.489 ± 0.024	0.514CysGlu: 0.514 ± 0.025	0.48CysPhe: 0.48 ± 0.026	0.806CysGly: 0.806 ± 0.029	0.243CysHis: 0.243 ± 0.017	0.692CysIle: 0.692 ± 0.029	0.377CysLys: 0.377 ± 0.021	1.077CysLeu: 1.077 ± 0.037	0.256CysMet: 0.256 ± 0.015	0.312CysAsn: 0.312 ± 0.017	0.402CysPro: 0.402 ± 0.021	0.431CysGln: 0.431 ± 0.018	0.44CysArg: 0.44 ± 0.022	0.692CysSer: 0.692 ± 0.031	0.454CysThr: 0.454 ± 0.023	0.633CysVal: 0.633 ± 0.025	0.099CysTrp: 0.099 ± 0.012	0.283CysTyr: 0.283 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.277AspAla: 5.277 ± 0.093	0.487AspCys: 0.487 ± 0.025	2.667AspAsp: 2.667 ± 0.061	3.282AspGlu: 3.282 ± 0.073	2.41AspPhe: 2.41 ± 0.054	3.339AspGly: 3.339 ± 0.087	1.247AspHis: 1.247 ± 0.037	3.353AspIle: 3.353 ± 0.057	2.342AspLys: 2.342 ± 0.051	5.507AspLeu: 5.507 ± 0.073	1.227AspMet: 1.227 ± 0.038	1.805AspAsn: 1.805 ± 0.05	2.054AspPro: 2.054 ± 0.049	2.709AspGln: 2.709 ± 0.061	2.258AspArg: 2.258 ± 0.061	2.762AspSer: 2.762 ± 0.061	2.249AspThr: 2.249 ± 0.052	3.588AspVal: 3.588 ± 0.07	0.756AspTrp: 0.756 ± 0.024	1.931AspTyr: 1.931 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	5.181GluAla: 5.181 ± 0.092	0.399GluCys: 0.399 ± 0.02	2.648GluAsp: 2.648 ± 0.062	3.039GluGlu: 3.039 ± 0.081	2.246GluPhe: 2.246 ± 0.054	3.13GluGly: 3.13 ± 0.072	1.609GluHis: 1.609 ± 0.045	4.144GluIle: 4.144 ± 0.071	3.873GluLys: 3.873 ± 0.081	6.067GluLeu: 6.067 ± 0.091	1.571GluMet: 1.571 ± 0.04	2.873GluAsn: 2.873 ± 0.059	1.746GluPro: 1.746 ± 0.046	4.153GluGln: 4.153 ± 0.063	2.95GluArg: 2.95 ± 0.061	2.962GluSer: 2.962 ± 0.065	2.865GluThr: 2.865 ± 0.06	3.448GluVal: 3.448 ± 0.059	0.725GluTrp: 0.725 ± 0.028	1.752GluTyr: 1.752 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	4.03PheAla: 4.03 ± 0.068	0.521PheCys: 0.521 ± 0.025	2.66PheAsp: 2.66 ± 0.055	2.574PheGlu: 2.574 ± 0.059	1.956PhePhe: 1.956 ± 0.051	3.171PheGly: 3.171 ± 0.071	0.853PheHis: 0.853 ± 0.028	3.105PheIle: 3.105 ± 0.072	2.498PheLys: 2.498 ± 0.056	3.79PheLeu: 3.79 ± 0.086	1.13PheMet: 1.13 ± 0.036	2.092PheAsn: 2.092 ± 0.047	1.475PhePro: 1.475 ± 0.046	1.671PheGln: 1.671 ± 0.05	1.393PheArg: 1.393 ± 0.04	3.334PheSer: 3.334 ± 0.062	2.095PheThr: 2.095 ± 0.051	2.482PheVal: 2.482 ± 0.052	0.614PheTrp: 0.614 ± 0.032	1.486PheTyr: 1.486 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	5.769GlyAla: 5.769 ± 0.112	0.849GlyCys: 0.849 ± 0.032	3.015GlyAsp: 3.015 ± 0.062	3.532GlyGlu: 3.532 ± 0.071	3.283GlyPhe: 3.283 ± 0.068	4.783GlyGly: 4.783 ± 0.104	1.612GlyHis: 1.612 ± 0.043	4.777GlyIle: 4.777 ± 0.079	3.78GlyLys: 3.78 ± 0.069	7.441GlyLeu: 7.441 ± 0.105	1.979GlyMet: 1.979 ± 0.049	2.574GlyAsn: 2.574 ± 0.085	1.547GlyPro: 1.547 ± 0.05	3.21GlyGln: 3.21 ± 0.066	2.828GlyArg: 2.828 ± 0.066	4.095GlySer: 4.095 ± 0.091	3.507GlyThr: 3.507 ± 0.086	4.709GlyVal: 4.709 ± 0.075	0.964GlyTrp: 0.964 ± 0.038	2.471GlyTyr: 2.471 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.277HisAla: 2.277 ± 0.046	0.268HisCys: 0.268 ± 0.017	1.15HisAsp: 1.15 ± 0.034	1.222HisGlu: 1.222 ± 0.038	1.199HisPhe: 1.199 ± 0.031	1.613HisGly: 1.613 ± 0.044	0.73HisHis: 0.73 ± 0.036	1.566HisIle: 1.566 ± 0.043	0.934HisLys: 0.934 ± 0.033	2.499HisLeu: 2.499 ± 0.067	0.569HisMet: 0.569 ± 0.022	0.766HisAsn: 0.766 ± 0.029	1.351HisPro: 1.351 ± 0.042	1.331HisGln: 1.331 ± 0.035	1.009HisArg: 1.009 ± 0.034	1.368HisSer: 1.368 ± 0.042	1.052HisThr: 1.052 ± 0.038	1.424HisVal: 1.424 ± 0.037	0.362HisTrp: 0.362 ± 0.022	0.964HisTyr: 0.964 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.857IleAla: 6.857 ± 0.088	0.755IleCys: 0.755 ± 0.031	3.95IleAsp: 3.95 ± 0.07	4.354IleGlu: 4.354 ± 0.067	2.708IlePhe: 2.708 ± 0.063	4.916IleGly: 4.916 ± 0.095	1.454IleHis: 1.454 ± 0.035	3.872IleIle: 3.872 ± 0.08	3.149IleLys: 3.149 ± 0.058	6.231IleLeu: 6.231 ± 0.093	1.438IleMet: 1.438 ± 0.043	2.758IleAsn: 2.758 ± 0.063	2.806IlePro: 2.806 ± 0.061	3.666IleGln: 3.666 ± 0.063	2.932IleArg: 2.932 ± 0.053	4.511IleSer: 4.511 ± 0.069	3.111IleThr: 3.111 ± 0.061	4.039IleVal: 4.039 ± 0.071	0.728IleTrp: 0.728 ± 0.028	2.064IleTyr: 2.064 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	5.444LysAla: 5.444 ± 0.089	0.31LysCys: 0.31 ± 0.017	2.948LysAsp: 2.948 ± 0.061	2.935LysGlu: 2.935 ± 0.071	1.93LysPhe: 1.93 ± 0.043	3.126LysGly: 3.126 ± 0.06	1.215LysHis: 1.215 ± 0.035	3.945LysIle: 3.945 ± 0.076	3.402LysLys: 3.402 ± 0.063	5.158LysLeu: 5.158 ± 0.086	1.585LysMet: 1.585 ± 0.041	2.769LysAsn: 2.769 ± 0.07	2.335LysPro: 2.335 ± 0.055	3.102LysGln: 3.102 ± 0.058	2.425LysArg: 2.425 ± 0.057	3.109LysSer: 3.109 ± 0.069	3.128LysThr: 3.128 ± 0.067	3.563LysVal: 3.563 ± 0.067	0.61LysTrp: 0.61 ± 0.026	1.625LysTyr: 1.625 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	9.875LeuAla: 9.875 ± 0.118	1.099LeuCys: 1.099 ± 0.038	5.553LeuAsp: 5.553 ± 0.082	5.738LeuGlu: 5.738 ± 0.1	4.286LeuPhe: 4.286 ± 0.086	7.167LeuGly: 7.167 ± 0.099	2.247LeuHis: 2.247 ± 0.056	6.819LeuIle: 6.819 ± 0.093	6.608LeuLys: 6.608 ± 0.1	9.987LeuLeu: 9.987 ± 0.151	2.893LeuMet: 2.893 ± 0.061	5.446LeuAsn: 5.446 ± 0.071	4.706LeuPro: 4.706 ± 0.084	4.851LeuGln: 4.851 ± 0.089	4.192LeuArg: 4.192 ± 0.072	7.479LeuSer: 7.479 ± 0.108	5.526LeuThr: 5.526 ± 0.077	5.841LeuVal: 5.841 ± 0.084	1.258LeuTrp: 1.258 ± 0.042	2.789LeuTyr: 2.789 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.429MetAla: 2.429 ± 0.055	0.222MetCys: 0.222 ± 0.017	1.15MetAsp: 1.15 ± 0.033	1.014MetGlu: 1.014 ± 0.035	0.906MetPhe: 0.906 ± 0.036	1.776MetGly: 1.776 ± 0.042	0.686MetHis: 0.686 ± 0.028	1.697MetIle: 1.697 ± 0.037	1.526MetLys: 1.526 ± 0.038	2.84MetLeu: 2.84 ± 0.053	0.833MetMet: 0.833 ± 0.03	1.453MetAsn: 1.453 ± 0.042	1.373MetPro: 1.373 ± 0.041	1.613MetGln: 1.613 ± 0.049	1.199MetArg: 1.199 ± 0.045	1.819MetSer: 1.819 ± 0.044	1.553MetThr: 1.553 ± 0.045	1.54MetVal: 1.54 ± 0.045	0.228MetTrp: 0.228 ± 0.017	0.581MetTyr: 0.581 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	4.09AsnAla: 4.09 ± 0.082	0.371AsnCys: 0.371 ± 0.021	2.111AsnAsp: 2.111 ± 0.046	2.227AsnGlu: 2.227 ± 0.051	1.907AsnPhe: 1.907 ± 0.048	2.969AsnGly: 2.969 ± 0.084	0.963AsnHis: 0.963 ± 0.035	3.159AsnIle: 3.159 ± 0.068	2.106AsnLys: 2.106 ± 0.052	4.381AsnLeu: 4.381 ± 0.064	1.019AsnMet: 1.019 ± 0.03	1.746AsnAsn: 1.746 ± 0.059	2.226AsnPro: 2.226 ± 0.048	2.319AsnGln: 2.319 ± 0.056	1.707AsnArg: 1.707 ± 0.045	2.691AsnSer: 2.691 ± 0.061	2.439AsnThr: 2.439 ± 0.053	2.736AsnVal: 2.736 ± 0.065	0.562AsnTrp: 0.562 ± 0.027	1.482AsnTyr: 1.482 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	4.099ProAla: 4.099 ± 0.075	0.283ProCys: 0.283 ± 0.018	2.144ProAsp: 2.144 ± 0.056	3.398ProGlu: 3.398 ± 0.064	1.747ProPhe: 1.747 ± 0.045	1.802ProGly: 1.802 ± 0.046	0.989ProHis: 0.989 ± 0.032	2.47ProIle: 2.47 ± 0.061	2.305ProLys: 2.305 ± 0.059	4.042ProLeu: 4.042 ± 0.072	1.065ProMet: 1.065 ± 0.035	1.952ProAsn: 1.952 ± 0.041	1.113ProPro: 1.113 ± 0.043	1.979ProGln: 1.979 ± 0.049	1.445ProArg: 1.445 ± 0.046	2.371ProSer: 2.371 ± 0.048	1.758ProThr: 1.758 ± 0.04	3.156ProVal: 3.156 ± 0.069	0.472ProTrp: 0.472 ± 0.026	1.375ProTyr: 1.375 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	5.384GlnAla: 5.384 ± 0.103	0.409GlnCys: 0.409 ± 0.024	2.404GlnAsp: 2.404 ± 0.046	2.481GlnGlu: 2.481 ± 0.056	2.197GlnPhe: 2.197 ± 0.047	3.215GlnGly: 3.215 ± 0.056	1.722GlnHis: 1.722 ± 0.044	3.312GlnIle: 3.312 ± 0.064	2.987GlnLys: 2.987 ± 0.058	5.856GlnLeu: 5.856 ± 0.108	1.297GlnMet: 1.297 ± 0.037	2.413GlnAsn: 2.413 ± 0.058	2.297GlnPro: 2.297 ± 0.052	4.019GlnGln: 4.019 ± 0.104	2.51GlnArg: 2.51 ± 0.056	3.132GlnSer: 3.132 ± 0.057	2.492GlnThr: 2.492 ± 0.057	3.225GlnVal: 3.225 ± 0.064	0.714GlnTrp: 0.714 ± 0.029	1.756GlnTyr: 1.756 ± 0.052	0.0GlnXaa: 0.0 ± 0.0
Arg	3.421ArgAla: 3.421 ± 0.063	0.346ArgCys: 0.346 ± 0.018	2.145ArgAsp: 2.145 ± 0.051	2.615ArgGlu: 2.615 ± 0.059	2.045ArgPhe: 2.045 ± 0.047	2.33ArgGly: 2.33 ± 0.048	1.072ArgHis: 1.072 ± 0.031	3.049ArgIle: 3.049 ± 0.063	2.285ArgLys: 2.285 ± 0.049	4.569ArgLeu: 4.569 ± 0.077	1.221ArgMet: 1.221 ± 0.037	1.742ArgAsn: 1.742 ± 0.039	1.745ArgPro: 1.745 ± 0.05	2.351ArgGln: 2.351 ± 0.05	2.005ArgArg: 2.005 ± 0.053	2.402ArgSer: 2.402 ± 0.054	2.04ArgThr: 2.04 ± 0.049	2.736ArgVal: 2.736 ± 0.056	0.523ArgTrp: 0.523 ± 0.021	1.68ArgTyr: 1.68 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.045SerAla: 6.045 ± 0.079	0.587SerCys: 0.587 ± 0.029	2.943SerAsp: 2.943 ± 0.074	3.303SerGlu: 3.303 ± 0.06	2.931SerPhe: 2.931 ± 0.06	4.536SerGly: 4.536 ± 0.083	1.44SerHis: 1.44 ± 0.037	4.368SerIle: 4.368 ± 0.082	3.259SerLys: 3.259 ± 0.063	6.481SerLeu: 6.481 ± 0.088	1.687SerMet: 1.687 ± 0.039	2.671SerAsn: 2.671 ± 0.065	2.311SerPro: 2.311 ± 0.055	2.895SerGln: 2.895 ± 0.063	2.572SerArg: 2.572 ± 0.055	4.3SerSer: 4.3 ± 0.082	3.182SerThr: 3.182 ± 0.072	3.928SerVal: 3.928 ± 0.069	0.742SerTrp: 0.742 ± 0.031	2.067SerTyr: 2.067 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	5.648ThrAla: 5.648 ± 0.102	0.401ThrCys: 0.401 ± 0.02	2.504ThrAsp: 2.504 ± 0.057	2.826ThrGlu: 2.826 ± 0.06	1.905ThrPhe: 1.905 ± 0.047	4.106ThrGly: 4.106 ± 0.089	1.179ThrHis: 1.179 ± 0.029	2.903ThrIle: 2.903 ± 0.059	2.088ThrLys: 2.088 ± 0.055	5.482ThrLeu: 5.482 ± 0.081	0.977ThrMet: 0.977 ± 0.033	1.626ThrAsn: 1.626 ± 0.058	2.493ThrPro: 2.493 ± 0.053	2.459ThrGln: 2.459 ± 0.046	1.988ThrArg: 1.988 ± 0.046	2.678ThrSer: 2.678 ± 0.06	2.411ThrThr: 2.411 ± 0.06	3.825ThrVal: 3.825 ± 0.089	0.606ThrTrp: 0.606 ± 0.025	1.387ThrTyr: 1.387 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	5.6ValAla: 5.6 ± 0.089	0.704ValCys: 0.704 ± 0.026	3.435ValAsp: 3.435 ± 0.076	3.809ValGlu: 3.809 ± 0.082	2.851ValPhe: 2.851 ± 0.063	4.112ValGly: 4.112 ± 0.073	1.41ValHis: 1.41 ± 0.039	4.483ValIle: 4.483 ± 0.069	3.657ValLys: 3.657 ± 0.069	7.201ValLeu: 7.201 ± 0.093	1.863ValMet: 1.863 ± 0.045	2.896ValAsn: 2.896 ± 0.054	2.681ValPro: 2.681 ± 0.051	3.119ValGln: 3.119 ± 0.062	2.737ValArg: 2.737 ± 0.06	4.125ValSer: 4.125 ± 0.072	3.521ValThr: 3.521 ± 0.09	4.247ValVal: 4.247 ± 0.083	0.773ValTrp: 0.773 ± 0.03	1.838ValTyr: 1.838 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.961TrpAla: 0.961 ± 0.031	0.148TrpCys: 0.148 ± 0.012	0.526TrpAsp: 0.526 ± 0.023	0.477TrpGlu: 0.477 ± 0.023	0.605TrpPhe: 0.605 ± 0.026	0.739TrpGly: 0.739 ± 0.03	0.356TrpHis: 0.356 ± 0.022	0.881TrpIle: 0.881 ± 0.03	0.664TrpLys: 0.664 ± 0.026	1.674TrpLeu: 1.674 ± 0.053	0.442TrpMet: 0.442 ± 0.021	0.594TrpAsn: 0.594 ± 0.024	0.4TrpPro: 0.4 ± 0.022	0.781TrpGln: 0.781 ± 0.029	0.593TrpArg: 0.593 ± 0.024	0.76TrpSer: 0.76 ± 0.031	0.601TrpThr: 0.601 ± 0.029	0.867TrpVal: 0.867 ± 0.031	0.14TrpTrp: 0.14 ± 0.012	0.362TrpTyr: 0.362 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.057TyrAla: 3.057 ± 0.061	0.358TyrCys: 0.358 ± 0.022	1.638TyrAsp: 1.638 ± 0.042	1.533TyrGlu: 1.533 ± 0.047	1.645TyrPhe: 1.645 ± 0.041	2.149TyrGly: 2.149 ± 0.053	0.65TyrHis: 0.65 ± 0.029	1.862TyrIle: 1.862 ± 0.048	1.542TyrLys: 1.542 ± 0.046	3.45TyrLeu: 3.45 ± 0.069	0.648TyrMet: 0.648 ± 0.026	1.195TyrAsn: 1.195 ± 0.046	1.383TyrPro: 1.383 ± 0.038	1.924TyrGln: 1.924 ± 0.05	1.6TyrArg: 1.6 ± 0.044	2.068TyrSer: 2.068 ± 0.045	1.554TyrThr: 1.554 ± 0.045	1.969TyrVal: 1.969 ± 0.049	0.485TyrTrp: 0.485 ± 0.025	0.984TyrTyr: 0.984 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3110 proteins (955441 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---