Simian T-lymphotropic virus 2

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Deltaretrovirus; Primate T-lymphotropic virus 2

Average proteome isoelectric point is 7.94

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|O09242|O09242_9DELA Pol protein (Fragment) OS=Simian T-lymphotropic virus 2 OX=33748 GN=pol PE=4 SV=1
MM1 pKa = 6.92GQTYY5 pKa = 10.25GLSPSPIPKK14 pKa = 10.02APRR17 pKa = 11.84GLSTHH22 pKa = 5.79HH23 pKa = 6.88WLNFLQASYY32 pKa = 10.71RR33 pKa = 11.84LQPGPSDD40 pKa = 4.38FDD42 pKa = 3.75FQQLRR47 pKa = 11.84RR48 pKa = 11.84FLKK51 pKa = 10.7LALKK55 pKa = 9.26TPIWLNPIDD64 pKa = 4.21YY65 pKa = 10.62SLLASLIPKK74 pKa = 8.85GYY76 pKa = 9.32PGRR79 pKa = 11.84TSEE82 pKa = 4.86IINVLIRR89 pKa = 11.84NQASPTPPPAPSLPEE104 pKa = 3.92PANPPPLQQPSAPPEE119 pKa = 3.9PHH121 pKa = 6.45TPPPYY126 pKa = 9.46IEE128 pKa = 5.11PPATHH133 pKa = 7.28CLPILHH139 pKa = 6.61PHH141 pKa = 6.84GAPSAHH147 pKa = 6.92RR148 pKa = 11.84PWQMKK153 pKa = 9.77DD154 pKa = 2.99LQAIKK159 pKa = 10.78QEE161 pKa = 4.53VNTSAPGSPQFMQTVRR177 pKa = 11.84LAIQQFDD184 pKa = 3.85PTAKK188 pKa = 10.47DD189 pKa = 3.57LQDD192 pKa = 3.86LLQYY196 pKa = 10.43LCSSLVVSLHH206 pKa = 5.5HH207 pKa = 5.89QQLHH211 pKa = 4.61TLITEE216 pKa = 4.28AEE218 pKa = 4.24TRR220 pKa = 11.84GMTGYY225 pKa = 11.08NPMAGPLRR233 pKa = 11.84MQANNPAQEE242 pKa = 4.26GLRR245 pKa = 11.84RR246 pKa = 11.84EE247 pKa = 4.29YY248 pKa = 11.06QNLWLAAFSALPGNTRR264 pKa = 11.84DD265 pKa = 4.02PSWAAILQGLEE276 pKa = 3.97EE277 pKa = 5.02PYY279 pKa = 10.54CALLEE284 pKa = 4.22RR285 pKa = 11.84LNVALDD291 pKa = 3.32NGLPEE296 pKa = 4.52GTPKK300 pKa = 10.76EE301 pKa = 4.23PILRR305 pKa = 11.84SLAYY309 pKa = 10.74SNANKK314 pKa = 10.2DD315 pKa = 3.9CQKK318 pKa = 10.69LAGSGPYY325 pKa = 9.91

Molecular weight: 35.85 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|O09243|O09243_9DELA Env polyprotein OS=Simian T-lymphotropic virus 2 OX=33748 GN=env PE=4 SV=1
QQ1 pKa = 7.44GLISPSCPRR10 pKa = 11.84PLPPSQKK17 pKa = 10.23VSDD20 pKa = 3.98TTVLGAGGQTSSQFKK35 pKa = 10.44LLRR38 pKa = 11.84SPLCVYY44 pKa = 10.73LPFRR48 pKa = 11.84KK49 pKa = 10.07APVTLPSCLLDD60 pKa = 3.97TDD62 pKa = 4.34NKK64 pKa = 8.68WAIIGRR70 pKa = 11.84DD71 pKa = 3.26ILQQCQSVLYY81 pKa = 10.39LPEE84 pKa = 6.13DD85 pKa = 3.8NLCEE89 pKa = 4.16GTPRR93 pKa = 11.84PSGRR97 pKa = 11.84MNSPRR102 pKa = 11.84LLPVATPSVIGLEE115 pKa = 4.32HH116 pKa = 6.97FPPPPQIDD124 pKa = 3.41QFPFKK129 pKa = 10.45PEE131 pKa = 3.61RR132 pKa = 11.84LQALTDD138 pKa = 3.97LVSKK142 pKa = 10.65ALEE145 pKa = 3.79ASYY148 pKa = 10.52IEE150 pKa = 5.24PYY152 pKa = 10.2SGPGNNPVFPVKK164 pKa = 10.43KK165 pKa = 10.1PNGKK169 pKa = 8.28WRR171 pKa = 11.84FIHH174 pKa = 7.35DD175 pKa = 4.17LRR177 pKa = 11.84ATNAITTTLASPSPGPPDD195 pKa = 3.56LTSLSTALPYY205 pKa = 10.7VQTIDD210 pKa = 3.54LADD213 pKa = 3.89AFFQIPLPKK222 pKa = 10.09QFQPYY227 pKa = 9.21FAFTIPQPCNYY238 pKa = 10.01GPGARR243 pKa = 11.84YY244 pKa = 9.04AWTVLPQGFKK254 pKa = 10.78NSPTLFEE261 pKa = 4.06QQLAAILSPIRR272 pKa = 11.84KK273 pKa = 8.93AFPTSTIIQYY283 pKa = 9.66MDD285 pKa = 5.98DD286 pKa = 3.96ILLASPAQGEE296 pKa = 4.21LQQLSKK302 pKa = 8.45MTLQALVTHH311 pKa = 6.77GLPVSQAPRR320 pKa = 11.84EE321 pKa = 4.08QTPGQIRR328 pKa = 11.84FLGQVISPDD337 pKa = 3.45HH338 pKa = 5.92ITYY341 pKa = 7.62EE342 pKa = 4.26TTPTIPMKK350 pKa = 10.59SQWTLAEE357 pKa = 4.11LQTVLGEE364 pKa = 4.19IQWVSKK370 pKa = 8.15GTPILRR376 pKa = 11.84KK377 pKa = 9.41HH378 pKa = 5.63LQCLYY383 pKa = 10.28SALRR387 pKa = 11.84GYY389 pKa = 10.48QDD391 pKa = 3.32PRR393 pKa = 11.84AHH395 pKa = 7.42LLLQKK400 pKa = 10.18QQLHH404 pKa = 6.52ALHH407 pKa = 7.52AIQPLQHH414 pKa = 6.2NCRR417 pKa = 11.84SRR419 pKa = 11.84LNPALPILGLISLSSSGTTSVLFQARR445 pKa = 11.84QRR447 pKa = 11.84WPLVWLHH454 pKa = 6.04TPHH457 pKa = 7.45PPTSLGPWGHH467 pKa = 7.24LLACTILTLDD477 pKa = 4.04KK478 pKa = 11.3YY479 pKa = 11.05SLQHH483 pKa = 6.15YY484 pKa = 9.66GRR486 pKa = 11.84LCQSLEE492 pKa = 4.17DD493 pKa = 3.93NMSNTALHH501 pKa = 7.02DD502 pKa = 3.91FVKK505 pKa = 10.62NSPHH509 pKa = 6.08PRR511 pKa = 11.84VGILIHH517 pKa = 6.41HH518 pKa = 7.02MSRR521 pKa = 11.84FHH523 pKa = 6.88NLGSQPSGPWKK534 pKa = 10.69ALLHH538 pKa = 6.35LPALLQAARR547 pKa = 11.84LLRR550 pKa = 11.84PLFTLSPVVLTTHH563 pKa = 7.05PVSSPTGLPKK573 pKa = 10.21KK574 pKa = 10.01AAYY577 pKa = 9.5VLWDD581 pKa = 3.46QTILRR586 pKa = 11.84HH587 pKa = 6.97DD588 pKa = 5.07SITLPPHH595 pKa = 6.67GSNSAQRR602 pKa = 11.84GEE604 pKa = 4.18LLALLSGLRR613 pKa = 11.84AAKK616 pKa = 9.7SWPSLNIFLDD626 pKa = 3.54SKK628 pKa = 11.12YY629 pKa = 10.38LIKK632 pKa = 10.63YY633 pKa = 7.54LHH635 pKa = 6.54SLATGAFLGTSTHH648 pKa = 5.47QSLYY652 pKa = 10.36AHH654 pKa = 7.08LPALLHH660 pKa = 5.97NKK662 pKa = 9.34VIYY665 pKa = 9.47LHH667 pKa = 7.05HH668 pKa = 6.67IRR670 pKa = 11.84SHH672 pKa = 6.09TNLPDD677 pKa = 5.11PISTLNEE684 pKa = 4.05YY685 pKa = 9.62TDD687 pKa = 3.69SLIIIAPLIPLTPQDD702 pKa = 3.78LHH704 pKa = 7.61RR705 pKa = 11.84LTHH708 pKa = 6.11CNSRR712 pKa = 11.84GPCFFRR718 pKa = 11.84ATPQQSQVALEE729 pKa = 4.23SRR731 pKa = 11.84VTPATSLNSQHH742 pKa = 6.59HH743 pKa = 6.0MPQGHH748 pKa = 6.55IRR750 pKa = 11.84RR751 pKa = 11.84GLLPNHH757 pKa = 6.73IWQGDD762 pKa = 3.75VTHH765 pKa = 6.32YY766 pKa = 10.04KK767 pKa = 9.96YY768 pKa = 10.41KK769 pKa = 9.06RR770 pKa = 11.84HH771 pKa = 6.41RR772 pKa = 11.84YY773 pKa = 8.24CLHH776 pKa = 5.38VWVDD780 pKa = 3.51TFSNAVSITCKK791 pKa = 9.99TKK793 pKa = 8.25EE794 pKa = 4.21TSSEE798 pKa = 4.24TVSALLHH805 pKa = 6.81AITILGKK812 pKa = 9.44PLSINTDD819 pKa = 2.97NGSAFLSQEE828 pKa = 3.67FQAFCTSWHH837 pKa = 6.34IRR839 pKa = 11.84HH840 pKa = 5.76STHH843 pKa = 5.85VPYY846 pKa = 10.98NPTSSGLVEE855 pKa = 4.04RR856 pKa = 11.84TNGIVKK862 pKa = 10.48ALLNKK867 pKa = 10.2YY868 pKa = 10.52LLDD871 pKa = 4.37SPNLPLDD878 pKa = 3.59NAISKK883 pKa = 9.28SLWTLNQLNVMSPSGKK899 pKa = 8.01TRR901 pKa = 11.84WQLHH905 pKa = 5.66HH906 pKa = 7.01GPRR909 pKa = 11.84LPPSLQIPQPSKK921 pKa = 11.32APANWYY927 pKa = 9.69YY928 pKa = 11.52VLTPGLTNQRR938 pKa = 11.84WKK940 pKa = 11.29GPLHH944 pKa = 7.12LSRR947 pKa = 11.84KK948 pKa = 7.84LQEE951 pKa = 4.2RR952 pKa = 11.84LLSIDD957 pKa = 5.54GSPQWIPWRR966 pKa = 11.84LLKK969 pKa = 9.93KK970 pKa = 7.73TVCPRR975 pKa = 11.84PDD977 pKa = 3.48GSEE980 pKa = 4.06LAAHH984 pKa = 7.48AATDD988 pKa = 4.02HH989 pKa = 5.13QHH991 pKa = 6.46HH992 pKa = 6.57GG993 pKa = 3.58

Molecular weight: 110.52 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

1804

325

993

601.3

66.79

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.596 ± 0.601

2.051 ± 0.532

3.16 ± 0.045

2.55 ± 0.442

2.716 ± 0.141

5.155 ± 0.105

4.213 ± 0.517

5.266 ± 0.294

3.215 ± 0.659

14.024 ± 0.228

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

0.998 ± 0.216

3.88 ± 0.262

10.421 ± 0.975

6.375 ± 0.284

4.712 ± 0.024

9.091 ± 0.854

6.707 ± 0.485

3.769 ± 0.508

2.162 ± 0.268

2.938 ± 0.161
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski