Amino acid dipepetide frequency for Euphorbia mosaic Peru virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.917AlaAla: 5.917 ± 2.03
0.986AlaCys: 0.986 ± 0.836
1.972AlaAsp: 1.972 ± 1.029
0.986AlaGlu: 0.986 ± 0.976
0.986AlaPhe: 0.986 ± 0.976
4.931AlaGly: 4.931 ± 1.624
0.0AlaHis: 0.0 ± 0.0
2.959AlaIle: 2.959 ± 0.894
4.931AlaLys: 4.931 ± 1.385
3.945AlaLeu: 3.945 ± 0.854
0.986AlaMet: 0.986 ± 0.62
1.972AlaAsn: 1.972 ± 1.24
2.959AlaPro: 2.959 ± 1.015
1.972AlaGln: 1.972 ± 1.029
3.945AlaArg: 3.945 ± 2.48
5.917AlaSer: 5.917 ± 1.077
3.945AlaThr: 3.945 ± 1.329
2.959AlaVal: 2.959 ± 1.262
1.972AlaTrp: 1.972 ± 0.693
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.986CysAla: 0.986 ± 1.025
0.0CysCys: 0.0 ± 0.0
0.986CysAsp: 0.986 ± 0.62
1.972CysGlu: 1.972 ± 0.693
0.986CysPhe: 0.986 ± 0.965
0.986CysGly: 0.986 ± 1.025
0.986CysHis: 0.986 ± 0.965
0.986CysIle: 0.986 ± 0.836
1.972CysLys: 1.972 ± 0.693
1.972CysLeu: 1.972 ± 1.003
0.0CysMet: 0.0 ± 0.0
0.986CysAsn: 0.986 ± 0.62
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.972CysSer: 1.972 ± 1.249
0.986CysThr: 0.986 ± 0.836
1.972CysVal: 1.972 ± 1.181
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.972AspAla: 1.972 ± 0.693
0.986AspCys: 0.986 ± 1.025
4.931AspAsp: 4.931 ± 2.326
1.972AspGlu: 1.972 ± 0.693
3.945AspPhe: 3.945 ± 1.071
1.972AspGly: 1.972 ± 1.003
0.986AspHis: 0.986 ± 1.025
3.945AspIle: 3.945 ± 2.059
0.986AspLys: 0.986 ± 0.836
5.917AspLeu: 5.917 ± 1.707
0.986AspMet: 0.986 ± 0.62
0.986AspAsn: 0.986 ± 0.836
1.972AspPro: 1.972 ± 0.942
0.986AspGln: 0.986 ± 0.976
3.945AspArg: 3.945 ± 1.329
5.917AspSer: 5.917 ± 1.493
1.972AspThr: 1.972 ± 1.24
5.917AspVal: 5.917 ± 2.079
0.986AspTrp: 0.986 ± 0.62
3.945AspTyr: 3.945 ± 1.839
0.0AspXaa: 0.0 ± 0.0
Glu
2.959GluAla: 2.959 ± 1.015
0.0GluCys: 0.0 ± 0.0
0.986GluAsp: 0.986 ± 0.976
1.972GluGlu: 1.972 ± 1.24
1.972GluPhe: 1.972 ± 1.45
4.931GluGly: 4.931 ± 1.385
0.0GluHis: 0.0 ± 0.0
0.986GluIle: 0.986 ± 0.976
0.0GluLys: 0.0 ± 0.0
2.959GluLeu: 2.959 ± 1.355
0.0GluMet: 0.0 ± 0.0
5.917GluAsn: 5.917 ± 2.376
0.986GluPro: 0.986 ± 0.836
2.959GluGln: 2.959 ± 1.405
1.972GluArg: 1.972 ± 1.003
3.945GluSer: 3.945 ± 1.314
0.0GluThr: 0.0 ± 0.0
0.986GluVal: 0.986 ± 0.976
0.986GluTrp: 0.986 ± 0.62
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.986PheAla: 0.986 ± 0.976
0.986PheCys: 0.986 ± 0.836
1.972PheAsp: 1.972 ± 0.693
0.0PheGlu: 0.0 ± 0.0
0.986PhePhe: 0.986 ± 0.62
2.959PheGly: 2.959 ± 0.952
0.986PheHis: 0.986 ± 0.62
3.945PheIle: 3.945 ± 1.885
2.959PheLys: 2.959 ± 2.314
5.917PheLeu: 5.917 ± 2.225
0.0PheMet: 0.0 ± 0.0
5.917PheAsn: 5.917 ± 1.55
1.972PhePro: 1.972 ± 1.029
4.931PheGln: 4.931 ± 0.878
2.959PheArg: 2.959 ± 1.289
0.986PheSer: 0.986 ± 0.965
0.986PheThr: 0.986 ± 0.62
0.0PheVal: 0.0 ± 0.0
2.959PheTrp: 2.959 ± 1.771
3.945PheTyr: 3.945 ± 1.864
0.0PheXaa: 0.0 ± 0.0
Gly
1.972GlyAla: 1.972 ± 1.24
1.972GlyCys: 1.972 ± 1.181
2.959GlyAsp: 2.959 ± 1.86
3.945GlyGlu: 3.945 ± 1.41
2.959GlyPhe: 2.959 ± 1.355
5.917GlyGly: 5.917 ± 1.789
1.972GlyHis: 1.972 ± 1.24
1.972GlyIle: 1.972 ± 0.693
6.903GlyLys: 6.903 ± 2.721
2.959GlyLeu: 2.959 ± 2.152
0.986GlyMet: 0.986 ± 0.976
1.972GlyAsn: 1.972 ± 1.198
3.945GlyPro: 3.945 ± 1.392
2.959GlyGln: 2.959 ± 1.405
1.972GlyArg: 1.972 ± 1.029
3.945GlySer: 3.945 ± 1.314
3.945GlyThr: 3.945 ± 1.804
2.959GlyVal: 2.959 ± 1.609
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.986HisAla: 0.986 ± 0.836
1.972HisCys: 1.972 ± 1.029
0.986HisAsp: 0.986 ± 0.836
0.986HisGlu: 0.986 ± 0.976
0.0HisPhe: 0.0 ± 0.0
0.986HisGly: 0.986 ± 0.965
0.986HisHis: 0.986 ± 1.025
1.972HisIle: 1.972 ± 1.45
1.972HisLys: 1.972 ± 1.181
2.959HisLeu: 2.959 ± 1.262
0.0HisMet: 0.0 ± 0.0
2.959HisAsn: 2.959 ± 1.86
2.959HisPro: 2.959 ± 1.355
2.959HisGln: 2.959 ± 0.894
1.972HisArg: 1.972 ± 1.181
1.972HisSer: 1.972 ± 1.24
1.972HisThr: 1.972 ± 1.672
3.945HisVal: 3.945 ± 1.864
0.986HisTrp: 0.986 ± 0.62
0.986HisTyr: 0.986 ± 0.62
0.0HisXaa: 0.0 ± 0.0
Ile
1.972IleAla: 1.972 ± 1.029
0.986IleCys: 0.986 ± 0.836
5.917IleAsp: 5.917 ± 3.015
0.0IleGlu: 0.0 ± 0.0
3.945IlePhe: 3.945 ± 1.839
1.972IleGly: 1.972 ± 0.693
0.0IleHis: 0.0 ± 0.0
3.945IleIle: 3.945 ± 1.371
6.903IleLys: 6.903 ± 0.791
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
1.972IlePro: 1.972 ± 1.029
2.959IleGln: 2.959 ± 1.219
6.903IleArg: 6.903 ± 2.466
3.945IleSer: 3.945 ± 1.788
6.903IleThr: 6.903 ± 1.709
4.931IleVal: 4.931 ± 1.468
1.972IleTrp: 1.972 ± 1.139
4.931IleTyr: 4.931 ± 3.039
0.0IleXaa: 0.0 ± 0.0
Lys
3.945LysAla: 3.945 ± 1.023
0.986LysCys: 0.986 ± 0.965
4.931LysAsp: 4.931 ± 3.1
2.959LysGlu: 2.959 ± 1.86
2.959LysPhe: 2.959 ± 0.793
1.972LysGly: 1.972 ± 0.693
1.972LysHis: 1.972 ± 1.029
4.931LysIle: 4.931 ± 1.352
0.986LysLys: 0.986 ± 1.025
3.945LysLeu: 3.945 ± 1.485
1.972LysMet: 1.972 ± 0.973
4.931LysAsn: 4.931 ± 1.624
3.945LysPro: 3.945 ± 1.533
0.0LysGln: 0.0 ± 0.0
3.945LysArg: 3.945 ± 2.505
3.945LysSer: 3.945 ± 0.987
2.959LysThr: 2.959 ± 1.869
5.917LysVal: 5.917 ± 3.852
0.0LysTrp: 0.0 ± 0.0
1.972LysTyr: 1.972 ± 0.693
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.972LeuCys: 1.972 ± 1.003
4.931LeuAsp: 4.931 ± 0.818
0.986LeuGlu: 0.986 ± 0.976
3.945LeuPhe: 3.945 ± 1.901
4.931LeuGly: 4.931 ± 1.969
3.945LeuHis: 3.945 ± 2.059
1.972LeuIle: 1.972 ± 1.24
3.945LeuLys: 3.945 ± 1.386
2.959LeuLeu: 2.959 ± 1.405
1.972LeuMet: 1.972 ± 1.139
5.917LeuAsn: 5.917 ± 3.413
4.931LeuPro: 4.931 ± 1.722
2.959LeuGln: 2.959 ± 1.984
6.903LeuArg: 6.903 ± 1.527
6.903LeuSer: 6.903 ± 2.52
3.945LeuThr: 3.945 ± 1.861
2.959LeuVal: 2.959 ± 0.793
0.0LeuTrp: 0.0 ± 0.0
2.959LeuTyr: 2.959 ± 0.793
0.0LeuXaa: 0.0 ± 0.0
Met
1.972MetAla: 1.972 ± 1.672
0.0MetCys: 0.0 ± 0.0
2.959MetAsp: 2.959 ± 1.743
0.0MetGlu: 0.0 ± 0.0
1.972MetPhe: 1.972 ± 1.672
1.972MetGly: 1.972 ± 1.003
0.986MetHis: 0.986 ± 0.836
0.986MetIle: 0.986 ± 0.976
0.0MetLys: 0.0 ± 0.0
1.972MetLeu: 1.972 ± 1.249
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.972MetPro: 1.972 ± 0.693
2.959MetGln: 2.959 ± 1.36
0.986MetArg: 0.986 ± 0.965
1.972MetSer: 1.972 ± 1.931
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.986MetTrp: 0.986 ± 0.62
1.972MetTyr: 1.972 ± 1.139
0.0MetXaa: 0.0 ± 0.0
Asn
5.917AsnAla: 5.917 ± 2.701
1.972AsnCys: 1.972 ± 1.029
1.972AsnAsp: 1.972 ± 0.693
1.972AsnGlu: 1.972 ± 1.672
1.972AsnPhe: 1.972 ± 1.952
0.986AsnGly: 0.986 ± 0.836
5.917AsnHis: 5.917 ± 3.486
3.945AsnIle: 3.945 ± 1.533
1.972AsnLys: 1.972 ± 1.24
2.959AsnLeu: 2.959 ± 2.249
1.972AsnMet: 1.972 ± 1.353
2.959AsnAsn: 2.959 ± 0.952
4.931AsnPro: 4.931 ± 0.906
0.0AsnGln: 0.0 ± 0.0
0.986AsnArg: 0.986 ± 0.836
5.917AsnSer: 5.917 ± 0.664
0.986AsnThr: 0.986 ± 0.965
4.931AsnVal: 4.931 ± 2.107
0.0AsnTrp: 0.0 ± 0.0
4.931AsnTyr: 4.931 ± 1.528
0.0AsnXaa: 0.0 ± 0.0
Pro
0.986ProAla: 0.986 ± 0.965
0.986ProCys: 0.986 ± 0.836
3.945ProAsp: 3.945 ± 2.915
1.972ProGlu: 1.972 ± 1.029
0.986ProPhe: 0.986 ± 0.62
0.986ProGly: 0.986 ± 0.62
3.945ProHis: 3.945 ± 1.839
4.931ProIle: 4.931 ± 2.877
2.959ProLys: 2.959 ± 2.508
4.931ProLeu: 4.931 ± 1.757
2.959ProMet: 2.959 ± 1.826
3.945ProAsn: 3.945 ± 1.41
1.972ProPro: 1.972 ± 1.029
1.972ProGln: 1.972 ± 1.029
6.903ProArg: 6.903 ± 1.929
8.876ProSer: 8.876 ± 3.052
1.972ProThr: 1.972 ± 1.003
2.959ProVal: 2.959 ± 0.894
2.959ProTrp: 2.959 ± 1.015
0.986ProTyr: 0.986 ± 0.836
0.0ProXaa: 0.0 ± 0.0
Gln
2.959GlnAla: 2.959 ± 0.793
0.986GlnCys: 0.986 ± 0.62
3.945GlnAsp: 3.945 ± 2.059
4.931GlnGlu: 4.931 ± 0.818
0.0GlnPhe: 0.0 ± 0.0
0.986GlnGly: 0.986 ± 1.025
1.972GlnHis: 1.972 ± 1.029
0.986GlnIle: 0.986 ± 0.62
1.972GlnLys: 1.972 ± 1.003
5.917GlnLeu: 5.917 ± 1.626
0.986GlnMet: 0.986 ± 0.965
0.0GlnAsn: 0.0 ± 0.0
0.986GlnPro: 0.986 ± 1.025
0.986GlnGln: 0.986 ± 0.965
1.972GlnArg: 1.972 ± 0.693
3.945GlnSer: 3.945 ± 0.987
0.0GlnThr: 0.0 ± 0.0
3.945GlnVal: 3.945 ± 2.277
0.0GlnTrp: 0.0 ± 0.0
1.972GlnTyr: 1.972 ± 0.693
0.0GlnXaa: 0.0 ± 0.0
Arg
6.903ArgAla: 6.903 ± 2.865
0.0ArgCys: 0.0 ± 0.0
4.931ArgAsp: 4.931 ± 2.052
1.972ArgGlu: 1.972 ± 1.24
8.876ArgPhe: 8.876 ± 2.533
4.931ArgGly: 4.931 ± 2.001
1.972ArgHis: 1.972 ± 1.139
4.931ArgIle: 4.931 ± 1.889
2.959ArgLys: 2.959 ± 0.793
4.931ArgLeu: 4.931 ± 1.768
0.986ArgMet: 0.986 ± 0.965
1.972ArgAsn: 1.972 ± 0.693
3.945ArgPro: 3.945 ± 1.386
0.0ArgGln: 0.0 ± 0.0
6.903ArgArg: 6.903 ± 2.706
2.959ArgSer: 2.959 ± 0.793
3.945ArgThr: 3.945 ± 1.071
4.931ArgVal: 4.931 ± 0.906
0.0ArgTrp: 0.0 ± 0.0
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
0.986SerAla: 0.986 ± 0.62
0.986SerCys: 0.986 ± 0.965
2.959SerAsp: 2.959 ± 1.015
0.986SerGlu: 0.986 ± 0.965
3.945SerPhe: 3.945 ± 2.059
5.917SerGly: 5.917 ± 2.225
0.986SerHis: 0.986 ± 0.836
7.89SerIle: 7.89 ± 1.81
4.931SerLys: 4.931 ± 0.818
3.945SerLeu: 3.945 ± 1.823
1.972SerMet: 1.972 ± 1.833
5.917SerAsn: 5.917 ± 2.03
10.848SerPro: 10.848 ± 5.318
3.945SerGln: 3.945 ± 1.41
5.917SerArg: 5.917 ± 1.667
6.903SerSer: 6.903 ± 3.928
9.862SerThr: 9.862 ± 3.331
4.931SerVal: 4.931 ± 1.861
0.986SerTrp: 0.986 ± 0.62
4.931SerTyr: 4.931 ± 1.265
0.0SerXaa: 0.0 ± 0.0
Thr
4.931ThrAla: 4.931 ± 2.107
0.986ThrCys: 0.986 ± 0.965
0.986ThrAsp: 0.986 ± 0.976
1.972ThrGlu: 1.972 ± 1.181
0.986ThrPhe: 0.986 ± 0.62
2.959ThrGly: 2.959 ± 0.793
2.959ThrHis: 2.959 ± 1.405
0.0ThrIle: 0.0 ± 0.0
3.945ThrLys: 3.945 ± 1.861
1.972ThrLeu: 1.972 ± 1.672
1.972ThrMet: 1.972 ± 1.003
2.959ThrAsn: 2.959 ± 1.405
6.903ThrPro: 6.903 ± 4.648
0.986ThrGln: 0.986 ± 1.025
1.972ThrArg: 1.972 ± 0.693
8.876ThrSer: 8.876 ± 3.714
1.972ThrThr: 1.972 ± 1.364
2.959ThrVal: 2.959 ± 1.417
0.0ThrTrp: 0.0 ± 0.0
1.972ThrTyr: 1.972 ± 1.24
0.0ThrXaa: 0.0 ± 0.0
Val
1.972ValAla: 1.972 ± 1.24
0.0ValCys: 0.0 ± 0.0
0.986ValAsp: 0.986 ± 0.62
1.972ValGlu: 1.972 ± 0.942
1.972ValPhe: 1.972 ± 1.139
2.959ValGly: 2.959 ± 1.743
0.986ValHis: 0.986 ± 1.025
4.931ValIle: 4.931 ± 1.404
4.931ValLys: 4.931 ± 2.052
3.945ValLeu: 3.945 ± 1.967
1.972ValMet: 1.972 ± 1.672
5.917ValAsn: 5.917 ± 2.077
3.945ValPro: 3.945 ± 1.015
3.945ValGln: 3.945 ± 0.987
4.931ValArg: 4.931 ± 2.577
7.89ValSer: 7.89 ± 1.501
1.972ValThr: 1.972 ± 1.672
2.959ValVal: 2.959 ± 0.793
0.986ValTrp: 0.986 ± 0.976
4.931ValTyr: 4.931 ± 2.052
0.0ValXaa: 0.0 ± 0.0
Trp
2.959TrpAla: 2.959 ± 1.86
0.0TrpCys: 0.0 ± 0.0
0.986TrpAsp: 0.986 ± 1.025
0.986TrpGlu: 0.986 ± 0.976
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.986TrpIle: 0.986 ± 0.62
1.972TrpLys: 1.972 ± 0.693
0.986TrpLeu: 0.986 ± 0.836
0.986TrpMet: 0.986 ± 0.836
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.986TrpGln: 0.986 ± 0.62
0.986TrpArg: 0.986 ± 0.836
0.986TrpSer: 0.986 ± 0.62
1.972TrpThr: 1.972 ± 0.942
0.986TrpVal: 0.986 ± 0.836
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.959TyrAla: 2.959 ± 2.508
0.986TyrCys: 0.986 ± 0.62
0.986TyrAsp: 0.986 ± 0.836
1.972TyrGlu: 1.972 ± 1.672
2.959TyrPhe: 2.959 ± 0.793
2.959TyrGly: 2.959 ± 0.894
2.959TyrHis: 2.959 ± 1.262
2.959TyrIle: 2.959 ± 1.262
1.972TyrLys: 1.972 ± 1.24
3.945TyrLeu: 3.945 ± 1.41
1.972TyrMet: 1.972 ± 1.063
2.959TyrAsn: 2.959 ± 0.793
0.986TyrPro: 0.986 ± 0.62
0.986TyrGln: 0.986 ± 0.62
1.972TyrArg: 1.972 ± 1.672
1.972TyrSer: 1.972 ± 0.693
1.972TyrThr: 1.972 ± 0.942
2.959TyrVal: 2.959 ± 1.949
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1015 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski