Amino acid dipepetide frequency for Mint virus X

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.409AlaAla: 17.409 ± 19.487
3.072AlaCys: 3.072 ± 1.084
4.096AlaAsp: 4.096 ± 3.475
3.072AlaGlu: 3.072 ± 3.096
4.096AlaPhe: 4.096 ± 1.507
5.632AlaGly: 5.632 ± 2.237
4.608AlaHis: 4.608 ± 0.496
4.608AlaIle: 4.608 ± 1.114
5.12AlaLys: 5.12 ± 1.781
13.313AlaLeu: 13.313 ± 3.65
2.048AlaMet: 2.048 ± 1.1
3.072AlaAsn: 3.072 ± 1.111
8.705AlaPro: 8.705 ± 2.264
2.56AlaGln: 2.56 ± 1.552
5.12AlaArg: 5.12 ± 1.41
6.656AlaSer: 6.656 ± 3.881
6.144AlaThr: 6.144 ± 1.825
4.096AlaVal: 4.096 ± 3.575
0.0AlaTrp: 0.0 ± 0.0
4.608AlaTyr: 4.608 ± 2.476
0.0AlaXaa: 0.0 ± 0.0
Cys
2.048CysAla: 2.048 ± 1.088
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
3.072CysGlu: 3.072 ± 1.609
0.0CysPhe: 0.0 ± 0.0
1.024CysGly: 1.024 ± 0.55
0.0CysHis: 0.0 ± 0.0
1.024CysIle: 1.024 ± 0.55
0.0CysLys: 0.0 ± 0.0
3.072CysLeu: 3.072 ± 0.866
0.0CysMet: 0.0 ± 0.0
0.512CysAsn: 0.512 ± 0.275
0.512CysPro: 0.512 ± 1.049
1.536CysGln: 1.536 ± 0.695
2.56CysArg: 2.56 ± 1.675
1.536CysSer: 1.536 ± 0.695
0.512CysThr: 0.512 ± 0.937
0.512CysVal: 0.512 ± 0.937
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.144AspAla: 6.144 ± 1.447
0.512AspCys: 0.512 ± 0.937
4.096AspAsp: 4.096 ± 0.797
4.096AspGlu: 4.096 ± 1.663
4.608AspPhe: 4.608 ± 1.624
4.608AspGly: 4.608 ± 1.231
0.512AspHis: 0.512 ± 0.275
1.024AspIle: 1.024 ± 0.55
1.024AspLys: 1.024 ± 0.55
3.584AspLeu: 3.584 ± 1.42
1.024AspMet: 1.024 ± 0.763
2.048AspAsn: 2.048 ± 0.914
4.608AspPro: 4.608 ± 2.245
3.072AspGln: 3.072 ± 1.651
2.048AspArg: 2.048 ± 0.832
5.12AspSer: 5.12 ± 1.766
0.0AspThr: 0.0 ± 0.0
4.608AspVal: 4.608 ± 1.784
2.56AspTrp: 2.56 ± 0.942
0.512AspTyr: 0.512 ± 1.049
0.0AspXaa: 0.0 ± 0.0
Glu
5.632GluAla: 5.632 ± 2.208
1.024GluCys: 1.024 ± 0.745
2.048GluAsp: 2.048 ± 0.832
3.072GluGlu: 3.072 ± 1.111
1.024GluPhe: 1.024 ± 0.55
1.024GluGly: 1.024 ± 0.869
1.536GluHis: 1.536 ± 0.805
2.048GluIle: 2.048 ± 0.75
2.56GluLys: 2.56 ± 1.376
7.168GluLeu: 7.168 ± 1.088
1.024GluMet: 1.024 ± 0.55
1.024GluAsn: 1.024 ± 0.55
6.144GluPro: 6.144 ± 2.578
0.0GluGln: 0.0 ± 0.0
3.584GluArg: 3.584 ± 1.307
2.048GluSer: 2.048 ± 0.832
2.048GluThr: 2.048 ± 1.491
5.12GluVal: 5.12 ± 2.033
1.024GluTrp: 1.024 ± 0.55
0.512GluTyr: 0.512 ± 1.007
0.0GluXaa: 0.0 ± 0.0
Phe
6.144PheAla: 6.144 ± 1.497
1.536PheCys: 1.536 ± 0.695
4.096PheAsp: 4.096 ± 1.5
1.024PheGlu: 1.024 ± 0.745
2.56PhePhe: 2.56 ± 1.552
6.144PheGly: 6.144 ± 3.917
2.048PheHis: 2.048 ± 1.1
1.536PheIle: 1.536 ± 1.198
2.048PheLys: 2.048 ± 1.1
5.632PheLeu: 5.632 ± 2.314
0.512PheMet: 0.512 ± 0.504
0.512PheAsn: 0.512 ± 0.275
3.072PhePro: 3.072 ± 1.566
1.536PheGln: 1.536 ± 0.825
1.536PheArg: 1.536 ± 0.825
2.048PheSer: 2.048 ± 0.75
3.584PheThr: 3.584 ± 0.908
2.048PheVal: 2.048 ± 1.491
0.512PheTrp: 0.512 ± 0.275
1.536PheTyr: 1.536 ± 0.695
0.0PheXaa: 0.0 ± 0.0
Gly
7.68GlyAla: 7.68 ± 2.669
2.048GlyCys: 2.048 ± 1.651
4.608GlyAsp: 4.608 ± 1.849
1.024GlyGlu: 1.024 ± 0.745
2.048GlyPhe: 2.048 ± 0.75
3.584GlyGly: 3.584 ± 2.371
2.56GlyHis: 2.56 ± 3.295
2.048GlyIle: 2.048 ± 1.136
3.584GlyLys: 3.584 ± 2.184
4.096GlyLeu: 4.096 ± 3.049
0.512GlyMet: 0.512 ± 0.883
1.536GlyAsn: 1.536 ± 0.825
4.608GlyPro: 4.608 ± 1.351
1.536GlyGln: 1.536 ± 0.805
3.584GlyArg: 3.584 ± 0.794
2.048GlySer: 2.048 ± 1.856
4.096GlyThr: 4.096 ± 1.558
2.56GlyVal: 2.56 ± 1.415
2.048GlyTrp: 2.048 ± 1.028
0.512GlyTyr: 0.512 ± 0.275
0.0GlyXaa: 0.0 ± 0.0
His
4.096HisAla: 4.096 ± 1.397
0.0HisCys: 0.0 ± 0.0
2.048HisAsp: 2.048 ± 1.066
1.024HisGlu: 1.024 ± 0.55
3.584HisPhe: 3.584 ± 0.963
2.048HisGly: 2.048 ± 0.75
2.048HisHis: 2.048 ± 0.861
2.56HisIle: 2.56 ± 0.942
1.536HisLys: 1.536 ± 0.825
2.048HisLeu: 2.048 ± 1.136
0.0HisMet: 0.0 ± 0.0
2.048HisAsn: 2.048 ± 1.1
2.048HisPro: 2.048 ± 1.1
1.536HisGln: 1.536 ± 0.879
3.072HisArg: 3.072 ± 1.715
4.096HisSer: 4.096 ± 2.143
3.584HisThr: 3.584 ± 1.419
1.536HisVal: 1.536 ± 0.879
0.0HisTrp: 0.0 ± 0.0
1.024HisTyr: 1.024 ± 0.869
0.0HisXaa: 0.0 ± 0.0
Ile
5.12IleAla: 5.12 ± 2.033
1.024IleCys: 1.024 ± 1.309
0.0IleAsp: 0.0 ± 0.0
3.072IleGlu: 3.072 ± 1.084
2.048IlePhe: 2.048 ± 1.028
2.048IleGly: 2.048 ± 1.1
2.048IleHis: 2.048 ± 1.856
1.536IleIle: 1.536 ± 0.879
1.536IleLys: 1.536 ± 0.825
5.12IleLeu: 5.12 ± 0.53
2.048IleMet: 2.048 ± 1.1
1.536IleAsn: 1.536 ± 0.825
3.072IlePro: 3.072 ± 1.651
0.512IleGln: 0.512 ± 0.275
5.12IleArg: 5.12 ± 1.646
2.048IleSer: 2.048 ± 1.738
5.12IleThr: 5.12 ± 3.304
3.072IleVal: 3.072 ± 2.3
0.512IleTrp: 0.512 ± 1.049
1.024IleTyr: 1.024 ± 0.55
0.0IleXaa: 0.0 ± 0.0
Lys
3.072LysAla: 3.072 ± 0.928
0.512LysCys: 0.512 ± 0.275
1.536LysAsp: 1.536 ± 0.695
3.584LysGlu: 3.584 ± 0.661
2.048LysPhe: 2.048 ± 1.764
1.536LysGly: 1.536 ± 0.695
1.536LysHis: 1.536 ± 0.825
1.024LysIle: 1.024 ± 0.55
2.048LysLys: 2.048 ± 1.1
5.632LysLeu: 5.632 ± 3.026
0.0LysMet: 0.0 ± 0.0
0.512LysAsn: 0.512 ± 0.275
2.56LysPro: 2.56 ± 1.652
2.048LysGln: 2.048 ± 1.1
2.048LysArg: 2.048 ± 0.914
2.56LysSer: 2.56 ± 1.376
5.632LysThr: 5.632 ± 1.463
1.536LysVal: 1.536 ± 0.825
0.512LysTrp: 0.512 ± 0.883
1.024LysTyr: 1.024 ± 0.55
0.0LysXaa: 0.0 ± 0.0
Leu
8.705LeuAla: 8.705 ± 4.112
2.56LeuCys: 2.56 ± 1.024
6.656LeuAsp: 6.656 ± 1.975
5.12LeuGlu: 5.12 ± 1.267
5.12LeuPhe: 5.12 ± 2.134
5.12LeuGly: 5.12 ± 0.969
4.096LeuHis: 4.096 ± 2.201
4.608LeuIle: 4.608 ± 0.496
6.656LeuLys: 6.656 ± 1.487
11.265LeuLeu: 11.265 ± 3.268
0.512LeuMet: 0.512 ± 0.873
3.584LeuAsn: 3.584 ± 1.926
9.729LeuPro: 9.729 ± 4.358
4.096LeuGln: 4.096 ± 0.588
5.632LeuArg: 5.632 ± 0.912
5.632LeuSer: 5.632 ± 1.022
8.193LeuThr: 8.193 ± 1.487
2.56LeuVal: 2.56 ± 1.273
1.536LeuTrp: 1.536 ± 0.879
1.536LeuTyr: 1.536 ± 0.825
0.0LeuXaa: 0.0 ± 0.0
Met
1.536MetAla: 1.536 ± 0.825
0.0MetCys: 0.0 ± 0.0
1.024MetAsp: 1.024 ± 0.869
0.0MetGlu: 0.0 ± 0.0
1.024MetPhe: 1.024 ± 0.55
1.024MetGly: 1.024 ± 0.55
1.024MetHis: 1.024 ± 0.55
1.024MetIle: 1.024 ± 0.55
1.536MetLys: 1.536 ± 0.825
1.024MetLeu: 1.024 ± 0.55
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.512MetPro: 0.512 ± 1.049
1.536MetGln: 1.536 ± 0.825
2.56MetArg: 2.56 ± 1.376
0.512MetSer: 0.512 ± 0.937
0.512MetThr: 0.512 ± 0.883
1.024MetVal: 1.024 ± 0.745
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.024AsnAla: 1.024 ± 0.55
0.512AsnCys: 0.512 ± 0.275
1.024AsnAsp: 1.024 ± 0.55
1.024AsnGlu: 1.024 ± 0.55
1.024AsnPhe: 1.024 ± 0.55
1.536AsnGly: 1.536 ± 0.805
1.536AsnHis: 1.536 ± 1.217
2.56AsnIle: 2.56 ± 1.009
1.024AsnLys: 1.024 ± 0.869
1.024AsnLeu: 1.024 ± 0.55
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.56AsnPro: 2.56 ± 0.891
1.536AsnGln: 1.536 ± 0.825
1.536AsnArg: 1.536 ± 0.825
2.048AsnSer: 2.048 ± 0.75
2.56AsnThr: 2.56 ± 1.376
0.512AsnVal: 0.512 ± 0.275
0.0AsnTrp: 0.0 ± 0.0
2.048AsnTyr: 2.048 ± 0.75
0.0AsnXaa: 0.0 ± 0.0
Pro
7.168ProAla: 7.168 ± 2.924
1.536ProCys: 1.536 ± 0.805
4.096ProAsp: 4.096 ± 1.335
5.12ProGlu: 5.12 ± 2.033
4.608ProPhe: 4.608 ± 0.496
2.048ProGly: 2.048 ± 1.136
1.536ProHis: 1.536 ± 1.309
2.048ProIle: 2.048 ± 0.832
3.584ProLys: 3.584 ± 1.926
5.12ProLeu: 5.12 ± 3.917
3.072ProMet: 3.072 ± 0.84
0.0ProAsn: 0.0 ± 0.0
8.193ProPro: 8.193 ± 4.36
1.024ProGln: 1.024 ± 0.745
3.584ProArg: 3.584 ± 1.39
6.144ProSer: 6.144 ± 1.94
6.656ProThr: 6.656 ± 1.703
5.12ProVal: 5.12 ± 2.033
0.512ProTrp: 0.512 ± 0.275
1.024ProTyr: 1.024 ± 0.826
0.0ProXaa: 0.0 ± 0.0
Gln
2.56GlnAla: 2.56 ± 1.376
0.0GlnCys: 0.0 ± 0.0
1.536GlnAsp: 1.536 ± 0.825
0.512GlnGlu: 0.512 ± 0.275
1.536GlnPhe: 1.536 ± 0.695
3.072GlnGly: 3.072 ± 1.643
1.536GlnHis: 1.536 ± 0.805
2.048GlnIle: 2.048 ± 1.1
0.512GlnLys: 0.512 ± 0.275
5.632GlnLeu: 5.632 ± 1.486
0.512GlnMet: 0.512 ± 0.275
0.512GlnAsn: 0.512 ± 0.275
1.536GlnPro: 1.536 ± 0.825
2.56GlnGln: 2.56 ± 1.376
1.536GlnArg: 1.536 ± 0.805
3.584GlnSer: 3.584 ± 1.316
3.584GlnThr: 3.584 ± 1.926
0.0GlnVal: 0.0 ± 0.0
1.024GlnTrp: 1.024 ± 0.55
1.536GlnTyr: 1.536 ± 0.825
0.0GlnXaa: 0.0 ± 0.0
Arg
5.632ArgAla: 5.632 ± 1.433
0.512ArgCys: 0.512 ± 1.049
5.12ArgAsp: 5.12 ± 2.054
4.096ArgGlu: 4.096 ± 2.201
3.072ArgPhe: 3.072 ± 1.858
4.096ArgGly: 4.096 ± 2.093
2.56ArgHis: 2.56 ± 1.744
4.608ArgIle: 4.608 ± 1.523
1.024ArgLys: 1.024 ± 0.55
4.608ArgLeu: 4.608 ± 1.261
1.024ArgMet: 1.024 ± 0.55
2.048ArgAsn: 2.048 ± 0.861
4.096ArgPro: 4.096 ± 2.841
1.536ArgGln: 1.536 ± 0.825
2.56ArgArg: 2.56 ± 0.942
1.024ArgSer: 1.024 ± 0.928
3.072ArgThr: 3.072 ± 1.111
2.048ArgVal: 2.048 ± 0.75
1.024ArgTrp: 1.024 ± 0.55
3.072ArgTyr: 3.072 ± 1.111
0.0ArgXaa: 0.0 ± 0.0
Ser
7.168SerAla: 7.168 ± 1.037
0.512SerCys: 0.512 ± 0.275
5.12SerAsp: 5.12 ± 2.054
2.56SerGlu: 2.56 ± 1.376
2.56SerPhe: 2.56 ± 0.971
5.12SerGly: 5.12 ± 3.579
2.56SerHis: 2.56 ± 0.891
2.56SerIle: 2.56 ± 0.942
2.56SerLys: 2.56 ± 1.958
9.729SerLeu: 9.729 ± 1.687
0.0SerMet: 0.0 ± 0.0
2.048SerAsn: 2.048 ± 0.865
1.536SerPro: 1.536 ± 0.825
2.56SerGln: 2.56 ± 1.376
3.584SerArg: 3.584 ± 1.378
4.096SerSer: 4.096 ± 2.093
3.584SerThr: 3.584 ± 1.378
3.072SerVal: 3.072 ± 2.236
1.024SerTrp: 1.024 ± 1.309
2.048SerTyr: 2.048 ± 1.531
0.0SerXaa: 0.0 ± 0.0
Thr
6.144ThrAla: 6.144 ± 2.232
1.536ThrCys: 1.536 ± 0.805
2.56ThrAsp: 2.56 ± 1.415
2.048ThrGlu: 2.048 ± 0.75
6.656ThrPhe: 6.656 ± 1.799
2.56ThrGly: 2.56 ± 1.215
4.608ThrHis: 4.608 ± 1.048
4.608ThrIle: 4.608 ± 1.46
2.048ThrLys: 2.048 ± 0.914
6.656ThrLeu: 6.656 ± 1.137
0.0ThrMet: 0.0 ± 0.0
1.536ThrAsn: 1.536 ± 1.61
6.144ThrPro: 6.144 ± 2.222
1.024ThrGln: 1.024 ± 0.55
4.608ThrArg: 4.608 ± 2.5
5.632ThrSer: 5.632 ± 1.415
5.12ThrThr: 5.12 ± 2.033
6.144ThrVal: 6.144 ± 0.969
0.0ThrTrp: 0.0 ± 0.0
1.024ThrTyr: 1.024 ± 0.55
0.0ThrXaa: 0.0 ± 0.0
Val
5.12ValAla: 5.12 ± 2.77
0.512ValCys: 0.512 ± 1.049
3.584ValAsp: 3.584 ± 2.733
3.584ValGlu: 3.584 ± 1.307
1.536ValPhe: 1.536 ± 0.805
3.584ValGly: 3.584 ± 2.07
2.048ValHis: 2.048 ± 1.136
3.584ValIle: 3.584 ± 2.514
2.048ValLys: 2.048 ± 0.75
4.096ValLeu: 4.096 ± 1.07
2.048ValMet: 2.048 ± 1.1
0.0ValAsn: 0.0 ± 0.0
1.536ValPro: 1.536 ± 0.695
3.584ValGln: 3.584 ± 1.926
0.512ValArg: 0.512 ± 0.275
4.096ValSer: 4.096 ± 1.636
5.12ValThr: 5.12 ± 2.016
4.608ValVal: 4.608 ± 1.308
1.024ValTrp: 1.024 ± 0.745
1.024ValTyr: 1.024 ± 0.55
0.0ValXaa: 0.0 ± 0.0
Trp
2.56TrpAla: 2.56 ± 2.204
0.0TrpCys: 0.0 ± 0.0
0.512TrpAsp: 0.512 ± 0.275
1.024TrpGlu: 1.024 ± 0.745
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.512TrpLys: 0.512 ± 0.275
2.56TrpLeu: 2.56 ± 1.786
0.512TrpMet: 0.512 ± 0.275
2.56TrpAsn: 2.56 ± 0.702
0.512TrpPro: 0.512 ± 0.275
0.0TrpGln: 0.0 ± 0.0
0.512TrpArg: 0.512 ± 0.275
0.512TrpSer: 0.512 ± 0.275
0.512TrpThr: 0.512 ± 0.275
1.024TrpVal: 1.024 ± 0.55
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.072TyrAla: 3.072 ± 1.084
0.512TyrCys: 0.512 ± 0.937
2.048TyrAsp: 2.048 ± 1.1
1.536TyrGlu: 1.536 ± 0.825
1.024TyrPhe: 1.024 ± 0.55
0.512TyrGly: 0.512 ± 0.275
1.536TyrHis: 1.536 ± 0.825
2.56TyrIle: 2.56 ± 0.942
0.0TyrLys: 0.0 ± 0.0
1.536TyrLeu: 1.536 ± 0.825
0.512TyrMet: 0.512 ± 0.275
0.0TyrAsn: 0.0 ± 0.0
0.512TyrPro: 0.512 ± 1.007
1.536TyrGln: 1.536 ± 0.825
1.536TyrArg: 1.536 ± 1.075
2.56TyrSer: 2.56 ± 1.024
1.024TyrThr: 1.024 ± 0.869
2.048TyrVal: 2.048 ± 1.088
0.0TyrTrp: 0.0 ± 0.0
0.512TyrTyr: 0.512 ± 0.275
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1954 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski