Amino acid dipepetide frequency for Changjiang crawfish virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.724AlaAla: 9.724 ± 0.851
1.216AlaCys: 1.216 ± 0.694
3.647AlaAsp: 3.647 ± 1.37
4.052AlaGlu: 4.052 ± 0.532
3.241AlaPhe: 3.241 ± 0.284
8.509AlaGly: 8.509 ± 2.256
2.026AlaHis: 2.026 ± 1.156
4.052AlaIle: 4.052 ± 1.244
2.431AlaLys: 2.431 ± 1.388
5.267AlaLeu: 5.267 ± 1.261
3.241AlaMet: 3.241 ± 0.428
2.431AlaAsn: 2.431 ± 1.457
3.647AlaPro: 3.647 ± 0.052
1.621AlaGln: 1.621 ± 0.214
3.241AlaArg: 3.241 ± 0.284
6.483AlaSer: 6.483 ± 1.99
8.104AlaThr: 8.104 ± 2.487
8.509AlaVal: 8.509 ± 1.3
1.216AlaTrp: 1.216 ± 0.017
2.026AlaTyr: 2.026 ± 0.445
0.0AlaXaa: 0.0 ± 0.0
Cys
2.026CysAla: 2.026 ± 0.445
0.405CysCys: 0.405 ± 0.231
0.405CysAsp: 0.405 ± 0.231
0.81CysGlu: 0.81 ± 0.463
1.216CysPhe: 1.216 ± 0.729
0.405CysGly: 0.405 ± 0.231
0.405CysHis: 0.405 ± 0.231
0.81CysIle: 0.81 ± 0.463
0.405CysLys: 0.405 ± 0.231
0.81CysLeu: 0.81 ± 0.463
0.81CysMet: 0.81 ± 0.463
0.81CysAsn: 0.81 ± 0.249
1.216CysPro: 1.216 ± 0.694
0.405CysGln: 0.405 ± 0.231
0.405CysArg: 0.405 ± 0.48
0.0CysSer: 0.0 ± 0.0
0.81CysThr: 0.81 ± 0.463
0.405CysVal: 0.405 ± 0.231
0.0CysTrp: 0.0 ± 0.0
0.405CysTyr: 0.405 ± 0.231
0.0CysXaa: 0.0 ± 0.0
Asp
4.457AspAla: 4.457 ± 0.301
1.216AspCys: 1.216 ± 0.694
2.431AspAsp: 2.431 ± 0.676
4.862AspGlu: 4.862 ± 0.07
3.241AspPhe: 3.241 ± 0.995
3.241AspGly: 3.241 ± 0.428
1.216AspHis: 1.216 ± 0.017
2.431AspIle: 2.431 ± 0.035
2.836AspLys: 2.836 ± 0.196
5.673AspLeu: 5.673 ± 1.104
2.026AspMet: 2.026 ± 0.266
2.026AspAsn: 2.026 ± 0.445
0.405AspPro: 0.405 ± 0.231
1.216AspGln: 1.216 ± 0.017
0.81AspArg: 0.81 ± 0.96
3.241AspSer: 3.241 ± 0.284
1.216AspThr: 1.216 ± 0.017
6.078AspVal: 6.078 ± 1.335
0.81AspTrp: 0.81 ± 0.463
0.81AspTyr: 0.81 ± 0.249
0.0AspXaa: 0.0 ± 0.0
Glu
4.862GluAla: 4.862 ± 2.064
0.405GluCys: 0.405 ± 0.231
4.457GluAsp: 4.457 ± 1.122
2.026GluGlu: 2.026 ± 0.445
1.216GluPhe: 1.216 ± 0.017
4.862GluGly: 4.862 ± 2.775
1.216GluHis: 1.216 ± 0.017
3.241GluIle: 3.241 ± 0.428
2.836GluLys: 2.836 ± 1.619
4.862GluLeu: 4.862 ± 0.642
1.621GluMet: 1.621 ± 0.214
2.026GluAsn: 2.026 ± 1.156
2.026GluPro: 2.026 ± 0.266
2.836GluGln: 2.836 ± 0.196
2.431GluArg: 2.431 ± 1.388
4.052GluSer: 4.052 ± 0.532
1.621GluThr: 1.621 ± 0.497
2.431GluVal: 2.431 ± 0.676
0.405GluTrp: 0.405 ± 0.231
2.836GluTyr: 2.836 ± 0.196
0.0GluXaa: 0.0 ± 0.0
Phe
3.241PheAla: 3.241 ± 0.428
0.405PheCys: 0.405 ± 0.231
2.836PheAsp: 2.836 ± 0.196
2.431PheGlu: 2.431 ± 0.035
0.405PhePhe: 0.405 ± 0.48
4.052PheGly: 4.052 ± 2.313
1.216PheHis: 1.216 ± 0.017
2.836PheIle: 2.836 ± 0.196
2.431PheLys: 2.431 ± 0.035
2.026PheLeu: 2.026 ± 0.445
1.216PheMet: 1.216 ± 0.338
1.216PheAsn: 1.216 ± 0.694
1.621PhePro: 1.621 ± 0.214
2.026PheGln: 2.026 ± 0.977
3.241PheArg: 3.241 ± 2.417
3.241PheSer: 3.241 ± 1.706
1.216PheThr: 1.216 ± 0.017
4.457PheVal: 4.457 ± 0.301
0.0PheTrp: 0.0 ± 0.0
0.81PheTyr: 0.81 ± 0.463
0.0PheXaa: 0.0 ± 0.0
Gly
4.052GlyAla: 4.052 ± 0.532
0.405GlyCys: 0.405 ± 0.231
4.862GlyAsp: 4.862 ± 0.07
4.862GlyGlu: 4.862 ± 1.353
4.052GlyPhe: 4.052 ± 1.955
5.267GlyGly: 5.267 ± 0.162
1.621GlyHis: 1.621 ± 0.497
3.647GlyIle: 3.647 ± 0.659
5.673GlyLys: 5.673 ± 3.238
7.293GlyLeu: 7.293 ± 1.527
2.431GlyMet: 2.431 ± 1.388
3.647GlyAsn: 3.647 ± 0.764
2.431GlyPro: 2.431 ± 0.676
1.216GlyGln: 1.216 ± 0.017
3.241GlyArg: 3.241 ± 0.284
8.104GlySer: 8.104 ± 0.358
7.699GlyThr: 7.699 ± 5.564
7.293GlyVal: 7.293 ± 1.318
0.81GlyTrp: 0.81 ± 0.463
2.431GlyTyr: 2.431 ± 0.035
0.0GlyXaa: 0.0 ± 0.0
His
1.621HisAla: 1.621 ± 0.925
0.405HisCys: 0.405 ± 0.231
0.405HisAsp: 0.405 ± 0.231
2.026HisGlu: 2.026 ± 0.445
0.81HisPhe: 0.81 ± 0.463
1.621HisGly: 1.621 ± 0.214
0.0HisHis: 0.0 ± 0.0
1.216HisIle: 1.216 ± 0.017
1.216HisLys: 1.216 ± 0.694
1.216HisLeu: 1.216 ± 0.017
0.0HisMet: 0.0 ± 0.0
0.81HisAsn: 0.81 ± 0.463
0.81HisPro: 0.81 ± 0.463
0.405HisGln: 0.405 ± 0.48
1.621HisArg: 1.621 ± 0.214
0.81HisSer: 0.81 ± 0.463
2.026HisThr: 2.026 ± 0.266
3.241HisVal: 3.241 ± 0.284
0.405HisTrp: 0.405 ± 0.231
1.216HisTyr: 1.216 ± 0.694
0.0HisXaa: 0.0 ± 0.0
Ile
4.862IleAla: 4.862 ± 0.07
0.81IleCys: 0.81 ± 0.463
4.052IleAsp: 4.052 ± 0.179
1.621IleGlu: 1.621 ± 0.214
2.026IlePhe: 2.026 ± 0.977
6.078IleGly: 6.078 ± 0.624
1.216IleHis: 1.216 ± 0.694
1.621IleIle: 1.621 ± 0.925
2.431IleLys: 2.431 ± 1.388
4.052IleLeu: 4.052 ± 0.89
0.81IleMet: 0.81 ± 0.463
2.026IleAsn: 2.026 ± 0.266
3.647IlePro: 3.647 ± 2.186
0.405IleGln: 0.405 ± 0.231
2.836IleArg: 2.836 ± 0.196
4.862IleSer: 4.862 ± 0.781
2.836IleThr: 2.836 ± 1.226
3.647IleVal: 3.647 ± 0.052
0.405IleTrp: 0.405 ± 0.231
1.216IleTyr: 1.216 ± 0.729
0.0IleXaa: 0.0 ± 0.0
Lys
3.647LysAla: 3.647 ± 1.37
1.621LysCys: 1.621 ± 0.214
3.241LysAsp: 3.241 ± 1.85
2.431LysGlu: 2.431 ± 1.388
2.836LysPhe: 2.836 ± 1.619
4.052LysGly: 4.052 ± 0.179
0.81LysHis: 0.81 ± 0.249
2.026LysIle: 2.026 ± 1.156
1.621LysLys: 1.621 ± 0.214
5.267LysLeu: 5.267 ± 1.584
2.431LysMet: 2.431 ± 0.035
1.621LysAsn: 1.621 ± 0.214
2.836LysPro: 2.836 ± 0.515
2.431LysGln: 2.431 ± 0.676
2.431LysArg: 2.431 ± 0.676
3.647LysSer: 3.647 ± 0.659
3.241LysThr: 3.241 ± 1.139
3.241LysVal: 3.241 ± 0.428
1.216LysTrp: 1.216 ± 0.694
1.621LysTyr: 1.621 ± 0.214
0.0LysXaa: 0.0 ± 0.0
Leu
6.888LeuAla: 6.888 ± 1.047
2.026LeuCys: 2.026 ± 0.266
4.862LeuAsp: 4.862 ± 0.642
6.483LeuGlu: 6.483 ± 2.278
2.026LeuPhe: 2.026 ± 1.156
6.078LeuGly: 6.078 ± 0.087
1.621LeuHis: 1.621 ± 0.925
2.431LeuIle: 2.431 ± 1.388
4.457LeuLys: 4.457 ± 0.41
4.457LeuLeu: 4.457 ± 2.544
1.216LeuMet: 1.216 ± 0.017
2.431LeuAsn: 2.431 ± 0.676
2.431LeuPro: 2.431 ± 1.457
3.647LeuGln: 3.647 ± 0.659
5.267LeuArg: 5.267 ± 0.55
8.509LeuSer: 8.509 ± 1.545
6.078LeuThr: 6.078 ± 0.087
6.078LeuVal: 6.078 ± 0.798
1.621LeuTrp: 1.621 ± 0.214
2.026LeuTyr: 2.026 ± 0.266
0.0LeuXaa: 0.0 ± 0.0
Met
3.647MetAla: 3.647 ± 0.659
0.81MetCys: 0.81 ± 0.463
1.216MetAsp: 1.216 ± 0.017
0.81MetGlu: 0.81 ± 0.249
0.81MetPhe: 0.81 ± 0.249
2.026MetGly: 2.026 ± 0.266
0.81MetHis: 0.81 ± 0.249
1.621MetIle: 1.621 ± 0.214
1.621MetLys: 1.621 ± 0.925
3.241MetLeu: 3.241 ± 1.139
0.405MetMet: 0.405 ± 0.231
0.81MetAsn: 0.81 ± 0.463
1.621MetPro: 1.621 ± 0.214
1.216MetGln: 1.216 ± 0.729
2.026MetArg: 2.026 ± 1.156
1.621MetSer: 1.621 ± 0.214
0.81MetThr: 0.81 ± 0.463
2.836MetVal: 2.836 ± 0.515
0.81MetTrp: 0.81 ± 0.463
2.026MetTyr: 2.026 ± 0.266
0.0MetXaa: 0.0 ± 0.0
Asn
2.431AsnAla: 2.431 ± 0.035
0.405AsnCys: 0.405 ± 0.231
1.621AsnAsp: 1.621 ± 0.214
0.81AsnGlu: 0.81 ± 0.249
2.026AsnPhe: 2.026 ± 0.445
1.621AsnGly: 1.621 ± 0.497
0.81AsnHis: 0.81 ± 0.463
2.026AsnIle: 2.026 ± 0.445
1.216AsnLys: 1.216 ± 0.694
4.052AsnLeu: 4.052 ± 0.179
2.431AsnMet: 2.431 ± 0.676
2.836AsnAsn: 2.836 ± 0.515
3.647AsnPro: 3.647 ± 0.052
1.621AsnGln: 1.621 ± 1.209
2.836AsnArg: 2.836 ± 0.515
2.026AsnSer: 2.026 ± 0.266
2.836AsnThr: 2.836 ± 1.226
1.216AsnVal: 1.216 ± 0.017
1.621AsnTrp: 1.621 ± 0.497
0.81AsnTyr: 0.81 ± 0.249
0.0AsnXaa: 0.0 ± 0.0
Pro
2.431ProAla: 2.431 ± 0.035
0.405ProCys: 0.405 ± 0.231
2.026ProAsp: 2.026 ± 0.977
2.431ProGlu: 2.431 ± 1.388
2.431ProPhe: 2.431 ± 1.457
2.026ProGly: 2.026 ± 0.445
1.216ProHis: 1.216 ± 0.017
2.431ProIle: 2.431 ± 0.746
2.026ProLys: 2.026 ± 1.156
6.078ProLeu: 6.078 ± 0.624
2.431ProMet: 2.431 ± 0.676
2.026ProAsn: 2.026 ± 0.266
1.216ProPro: 1.216 ± 0.017
0.405ProGln: 0.405 ± 0.231
0.81ProArg: 0.81 ± 0.249
4.052ProSer: 4.052 ± 3.377
2.836ProThr: 2.836 ± 1.937
2.836ProVal: 2.836 ± 0.515
1.621ProTrp: 1.621 ± 0.214
2.836ProTyr: 2.836 ± 0.515
0.0ProXaa: 0.0 ± 0.0
Gln
1.216GlnAla: 1.216 ± 0.729
0.405GlnCys: 0.405 ± 0.231
0.81GlnAsp: 0.81 ± 0.463
1.216GlnGlu: 1.216 ± 0.017
1.621GlnPhe: 1.621 ± 0.214
4.052GlnGly: 4.052 ± 0.532
0.0GlnHis: 0.0 ± 0.0
1.216GlnIle: 1.216 ± 0.017
0.81GlnLys: 0.81 ± 0.463
2.026GlnLeu: 2.026 ± 0.266
0.405GlnMet: 0.405 ± 0.48
1.621GlnAsn: 1.621 ± 0.497
0.405GlnPro: 0.405 ± 0.231
0.81GlnGln: 0.81 ± 0.463
1.621GlnArg: 1.621 ± 0.925
3.647GlnSer: 3.647 ± 0.052
1.621GlnThr: 1.621 ± 1.92
2.431GlnVal: 2.431 ± 1.388
1.216GlnTrp: 1.216 ± 0.694
1.216GlnTyr: 1.216 ± 1.44
0.0GlnXaa: 0.0 ± 0.0
Arg
4.862ArgAla: 4.862 ± 0.07
0.405ArgCys: 0.405 ± 0.48
1.216ArgAsp: 1.216 ± 0.017
2.836ArgGlu: 2.836 ± 1.619
2.026ArgPhe: 2.026 ± 1.156
3.647ArgGly: 3.647 ± 0.052
1.216ArgHis: 1.216 ± 0.017
2.431ArgIle: 2.431 ± 0.676
4.052ArgLys: 4.052 ± 0.179
3.647ArgLeu: 3.647 ± 0.764
2.026ArgMet: 2.026 ± 0.266
1.621ArgAsn: 1.621 ± 0.497
2.836ArgPro: 2.836 ± 0.515
0.405ArgGln: 0.405 ± 0.48
3.241ArgArg: 3.241 ± 0.428
4.052ArgSer: 4.052 ± 0.89
2.026ArgThr: 2.026 ± 0.445
5.267ArgVal: 5.267 ± 0.55
0.405ArgTrp: 0.405 ± 0.231
3.241ArgTyr: 3.241 ± 0.995
0.0ArgXaa: 0.0 ± 0.0
Ser
5.673SerAla: 5.673 ± 1.03
0.81SerCys: 0.81 ± 0.249
2.836SerAsp: 2.836 ± 1.937
6.078SerGlu: 6.078 ± 1.335
2.836SerPhe: 2.836 ± 0.908
6.078SerGly: 6.078 ± 1.335
1.216SerHis: 1.216 ± 0.017
3.241SerIle: 3.241 ± 0.995
4.457SerLys: 4.457 ± 0.301
5.673SerLeu: 5.673 ± 1.104
2.431SerMet: 2.431 ± 0.035
3.241SerAsn: 3.241 ± 0.995
4.457SerPro: 4.457 ± 2.435
2.431SerGln: 2.431 ± 0.746
4.457SerArg: 4.457 ± 0.301
4.052SerSer: 4.052 ± 2.666
7.293SerThr: 7.293 ± 4.372
3.647SerVal: 3.647 ± 0.052
1.621SerTrp: 1.621 ± 1.209
1.621SerTyr: 1.621 ± 0.497
0.0SerXaa: 0.0 ± 0.0
Thr
8.104ThrAla: 8.104 ± 5.332
0.405ThrCys: 0.405 ± 0.231
3.241ThrAsp: 3.241 ± 0.995
1.621ThrGlu: 1.621 ± 0.925
2.836ThrPhe: 2.836 ± 0.515
4.862ThrGly: 4.862 ± 3.626
1.621ThrHis: 1.621 ± 0.925
5.673ThrIle: 5.673 ± 1.741
4.052ThrLys: 4.052 ± 1.244
6.888ThrLeu: 6.888 ± 2.47
2.026ThrMet: 2.026 ± 0.266
2.026ThrAsn: 2.026 ± 0.266
2.836ThrPro: 2.836 ± 0.515
1.621ThrGln: 1.621 ± 0.214
4.457ThrArg: 4.457 ± 1.122
4.862ThrSer: 4.862 ± 1.492
6.483ThrThr: 6.483 ± 0.567
4.457ThrVal: 4.457 ± 1.012
0.81ThrTrp: 0.81 ± 0.249
1.621ThrTyr: 1.621 ± 0.497
0.0ThrXaa: 0.0 ± 0.0
Val
5.267ValAla: 5.267 ± 0.55
0.405ValCys: 0.405 ± 0.231
3.647ValAsp: 3.647 ± 0.764
3.241ValGlu: 3.241 ± 0.428
3.241ValPhe: 3.241 ± 0.428
8.104ValGly: 8.104 ± 1.065
2.836ValHis: 2.836 ± 1.619
4.052ValIle: 4.052 ± 1.244
5.673ValLys: 5.673 ± 1.104
4.457ValLeu: 4.457 ± 0.41
1.621ValMet: 1.621 ± 0.214
2.836ValAsn: 2.836 ± 0.196
6.078ValPro: 6.078 ± 0.087
2.431ValGln: 2.431 ± 0.676
3.647ValArg: 3.647 ± 0.659
4.862ValSer: 4.862 ± 0.781
5.673ValThr: 5.673 ± 0.318
5.267ValVal: 5.267 ± 0.55
3.241ValTrp: 3.241 ± 0.284
2.836ValTyr: 2.836 ± 0.908
0.0ValXaa: 0.0 ± 0.0
Trp
1.621TrpAla: 1.621 ± 0.925
0.0TrpCys: 0.0 ± 0.0
2.026TrpAsp: 2.026 ± 0.266
0.81TrpGlu: 0.81 ± 0.463
1.621TrpPhe: 1.621 ± 0.214
0.405TrpGly: 0.405 ± 0.231
0.81TrpHis: 0.81 ± 0.249
0.81TrpIle: 0.81 ± 0.463
0.405TrpLys: 0.405 ± 0.231
2.026TrpLeu: 2.026 ± 0.266
0.405TrpMet: 0.405 ± 0.231
0.405TrpAsn: 0.405 ± 0.231
0.0TrpPro: 0.0 ± 0.0
1.216TrpGln: 1.216 ± 0.017
1.216TrpArg: 1.216 ± 0.017
1.216TrpSer: 1.216 ± 0.017
0.405TrpThr: 0.405 ± 0.231
2.026TrpVal: 2.026 ± 0.445
0.0TrpTrp: 0.0 ± 0.0
2.026TrpTyr: 2.026 ± 0.977
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.052TyrAla: 4.052 ± 1.955
0.0TyrCys: 0.0 ± 0.0
0.405TyrAsp: 0.405 ± 0.231
0.81TyrGlu: 0.81 ± 0.463
0.81TyrPhe: 0.81 ± 0.463
4.052TyrGly: 4.052 ± 1.955
0.0TyrHis: 0.0 ± 0.0
3.647TyrIle: 3.647 ± 0.764
1.621TyrLys: 1.621 ± 0.925
1.621TyrLeu: 1.621 ± 0.214
0.405TyrMet: 0.405 ± 0.231
2.431TyrAsn: 2.431 ± 0.746
0.405TyrPro: 0.405 ± 0.231
0.0TyrGln: 0.0 ± 0.0
1.621TyrArg: 1.621 ± 0.214
0.81TyrSer: 0.81 ± 0.249
5.673TyrThr: 5.673 ± 0.393
4.052TyrVal: 4.052 ± 1.244
1.216TyrTrp: 1.216 ± 0.017
0.405TyrTyr: 0.405 ± 0.231
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2469 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski