Amino acid dipepetide frequency for Komagataeibacter hansenii ATCC 23769

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.987AlaAla: 14.987 ± 0.175	1.608AlaCys: 1.608 ± 0.044	6.279AlaAsp: 6.279 ± 0.089	5.511AlaGlu: 5.511 ± 0.097	3.804AlaPhe: 3.804 ± 0.066	10.654AlaGly: 10.654 ± 0.119	3.238AlaHis: 3.238 ± 0.067	5.802AlaIle: 5.802 ± 0.087	2.295AlaLys: 2.295 ± 0.054	12.63AlaLeu: 12.63 ± 0.145	3.859AlaMet: 3.859 ± 0.065	2.604AlaAsn: 2.604 ± 0.055	6.311AlaPro: 6.311 ± 0.107	4.82AlaGln: 4.82 ± 0.086	9.997AlaArg: 9.997 ± 0.129	6.05AlaSer: 6.05 ± 0.086	6.901AlaThr: 6.901 ± 0.1	7.886AlaVal: 7.886 ± 0.114	1.717AlaTrp: 1.717 ± 0.048	2.29AlaTyr: 2.29 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.492CysAla: 1.492 ± 0.041	0.153CysCys: 0.153 ± 0.013	0.678CysAsp: 0.678 ± 0.025	0.439CysGlu: 0.439 ± 0.019	0.369CysPhe: 0.369 ± 0.02	1.212CysGly: 1.212 ± 0.035	0.353CysHis: 0.353 ± 0.022	0.558CysIle: 0.558 ± 0.022	0.174CysLys: 0.174 ± 0.014	1.119CysLeu: 1.119 ± 0.039	0.309CysMet: 0.309 ± 0.016	0.261CysAsn: 0.261 ± 0.017	0.625CysPro: 0.625 ± 0.021	0.256CysGln: 0.256 ± 0.014	0.777CysArg: 0.777 ± 0.029	0.56CysSer: 0.56 ± 0.021	0.58CysThr: 0.58 ± 0.025	0.832CysVal: 0.832 ± 0.033	0.141CysTrp: 0.141 ± 0.012	0.227CysTyr: 0.227 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	7.233AspAla: 7.233 ± 0.098	0.463AspCys: 0.463 ± 0.02	3.141AspAsp: 3.141 ± 0.059	2.795AspGlu: 2.795 ± 0.065	1.837AspPhe: 1.837 ± 0.043	5.337AspGly: 5.337 ± 0.096	1.469AspHis: 1.469 ± 0.041	3.609AspIle: 3.609 ± 0.06	1.093AspLys: 1.093 ± 0.04	5.815AspLeu: 5.815 ± 0.086	2.013AspMet: 2.013 ± 0.046	1.359AspAsn: 1.359 ± 0.035	3.529AspPro: 3.529 ± 0.067	1.514AspGln: 1.514 ± 0.041	4.115AspArg: 4.115 ± 0.072	2.292AspSer: 2.292 ± 0.046	3.15AspThr: 3.15 ± 0.053	4.301AspVal: 4.301 ± 0.07	0.854AspTrp: 0.854 ± 0.031	1.37AspTyr: 1.37 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	5.543GluAla: 5.543 ± 0.093	0.464GluCys: 0.464 ± 0.025	2.494GluAsp: 2.494 ± 0.055	2.543GluGlu: 2.543 ± 0.057	1.407GluPhe: 1.407 ± 0.041	3.693GluGly: 3.693 ± 0.055	1.355GluHis: 1.355 ± 0.038	2.906GluIle: 2.906 ± 0.061	1.769GluLys: 1.769 ± 0.051	4.292GluLeu: 4.292 ± 0.076	1.343GluMet: 1.343 ± 0.039	1.554GluAsn: 1.554 ± 0.037	1.826GluPro: 1.826 ± 0.052	2.012GluGln: 2.012 ± 0.054	4.137GluArg: 4.137 ± 0.073	2.031GluSer: 2.031 ± 0.051	2.993GluThr: 2.993 ± 0.06	3.121GluVal: 3.121 ± 0.06	0.654GluTrp: 0.654 ± 0.027	1.002GluTyr: 1.002 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.837PheAla: 3.837 ± 0.06	0.498PheCys: 0.498 ± 0.022	2.161PheAsp: 2.161 ± 0.053	1.559PheGlu: 1.559 ± 0.04	1.265PhePhe: 1.265 ± 0.036	3.329PheGly: 3.329 ± 0.069	0.914PheHis: 0.914 ± 0.031	1.654PheIle: 1.654 ± 0.045	0.586PheLys: 0.586 ± 0.024	3.207PheLeu: 3.207 ± 0.065	1.03PheMet: 1.03 ± 0.03	1.01PheAsn: 1.01 ± 0.035	1.675PhePro: 1.675 ± 0.04	0.895PheGln: 0.895 ± 0.03	2.29PheArg: 2.29 ± 0.052	2.255PheSer: 2.255 ± 0.053	1.909PheThr: 1.909 ± 0.047	2.608PheVal: 2.608 ± 0.058	0.496PheTrp: 0.496 ± 0.022	0.884PheTyr: 0.884 ± 0.034	0.001PheXaa: 0.001 ± 0.001
Gly	9.279GlyAla: 9.279 ± 0.119	1.061GlyCys: 1.061 ± 0.033	4.27GlyAsp: 4.27 ± 0.065	3.859GlyGlu: 3.859 ± 0.061	3.183GlyPhe: 3.183 ± 0.058	7.939GlyGly: 7.939 ± 0.16	2.65GlyHis: 2.65 ± 0.057	4.813GlyIle: 4.813 ± 0.076	2.515GlyLys: 2.515 ± 0.061	8.574GlyLeu: 8.574 ± 0.109	3.075GlyMet: 3.075 ± 0.065	2.33GlyAsn: 2.33 ± 0.057	3.532GlyPro: 3.532 ± 0.06	3.331GlyGln: 3.331 ± 0.063	6.605GlyArg: 6.605 ± 0.088	4.363GlySer: 4.363 ± 0.078	5.206GlyThr: 5.206 ± 0.101	6.335GlyVal: 6.335 ± 0.084	1.484GlyTrp: 1.484 ± 0.039	2.343GlyTyr: 2.343 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	3.479HisAla: 3.479 ± 0.067	0.263HisCys: 0.263 ± 0.019	2.092HisAsp: 2.092 ± 0.05	1.393HisGlu: 1.393 ± 0.038	0.956HisPhe: 0.956 ± 0.032	2.633HisGly: 2.633 ± 0.058	0.899HisHis: 0.899 ± 0.034	1.248HisIle: 1.248 ± 0.037	0.531HisLys: 0.531 ± 0.023	2.509HisLeu: 2.509 ± 0.054	0.752HisMet: 0.752 ± 0.027	0.71HisAsn: 0.71 ± 0.027	1.823HisPro: 1.823 ± 0.046	0.71HisGln: 0.71 ± 0.024	1.741HisArg: 1.741 ± 0.045	1.159HisSer: 1.159 ± 0.038	1.236HisThr: 1.236 ± 0.033	2.163HisVal: 2.163 ± 0.051	0.393HisTrp: 0.393 ± 0.02	0.698HisTyr: 0.698 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.754IleAla: 6.754 ± 0.085	0.629IleCys: 0.629 ± 0.024	3.159IleAsp: 3.159 ± 0.059	2.779IleGlu: 2.779 ± 0.061	1.644IlePhe: 1.644 ± 0.043	4.762IleGly: 4.762 ± 0.073	1.263IleHis: 1.263 ± 0.033	2.327IleIle: 2.327 ± 0.052	1.009IleLys: 1.009 ± 0.035	4.492IleLeu: 4.492 ± 0.076	1.415IleMet: 1.415 ± 0.042	1.389IleAsn: 1.389 ± 0.043	2.733IlePro: 2.733 ± 0.054	1.297IleGln: 1.297 ± 0.035	3.585IleArg: 3.585 ± 0.061	3.125IleSer: 3.125 ± 0.06	3.054IleThr: 3.054 ± 0.049	4.006IleVal: 4.006 ± 0.063	0.587IleTrp: 0.587 ± 0.023	1.052IleTyr: 1.052 ± 0.036	0.002IleXaa: 0.002 ± 0.001
Lys	2.743LysAla: 2.743 ± 0.06	0.163LysCys: 0.163 ± 0.013	1.262LysAsp: 1.262 ± 0.041	1.119LysGlu: 1.119 ± 0.043	0.691LysPhe: 0.691 ± 0.028	2.036LysGly: 2.036 ± 0.049	0.483LysHis: 0.483 ± 0.025	1.355LysIle: 1.355 ± 0.04	0.951LysLys: 0.951 ± 0.035	2.158LysLeu: 2.158 ± 0.051	0.668LysMet: 0.668 ± 0.025	0.733LysAsn: 0.733 ± 0.031	1.307LysPro: 1.307 ± 0.038	0.843LysGln: 0.843 ± 0.029	1.463LysArg: 1.463 ± 0.039	1.342LysSer: 1.342 ± 0.04	1.433LysThr: 1.433 ± 0.042	1.82LysVal: 1.82 ± 0.043	0.328LysTrp: 0.328 ± 0.018	0.558LysTyr: 0.558 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	11.625LeuAla: 11.625 ± 0.105	1.299LeuCys: 1.299 ± 0.038	5.72LeuAsp: 5.72 ± 0.082	4.41LeuGlu: 4.41 ± 0.081	3.51LeuPhe: 3.51 ± 0.074	7.782LeuGly: 7.782 ± 0.107	2.802LeuHis: 2.802 ± 0.058	4.113LeuIle: 4.113 ± 0.074	2.462LeuLys: 2.462 ± 0.063	9.769LeuLeu: 9.769 ± 0.143	2.618LeuMet: 2.618 ± 0.052	2.513LeuAsn: 2.513 ± 0.055	6.363LeuPro: 6.363 ± 0.095	2.896LeuGln: 2.896 ± 0.052	7.883LeuArg: 7.883 ± 0.099	7.173LeuSer: 7.173 ± 0.085	5.291LeuThr: 5.291 ± 0.065	6.945LeuVal: 6.945 ± 0.1	1.254LeuTrp: 1.254 ± 0.036	2.074LeuTyr: 2.074 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	3.76MetAla: 3.76 ± 0.071	0.255MetCys: 0.255 ± 0.016	1.51MetAsp: 1.51 ± 0.043	1.43MetGlu: 1.43 ± 0.035	0.852MetPhe: 0.852 ± 0.031	2.46MetGly: 2.46 ± 0.051	0.708MetHis: 0.708 ± 0.029	1.461MetIle: 1.461 ± 0.037	0.934MetLys: 0.934 ± 0.023	2.969MetLeu: 2.969 ± 0.061	0.886MetMet: 0.886 ± 0.031	0.894MetAsn: 0.894 ± 0.027	2.018MetPro: 2.018 ± 0.039	1.146MetGln: 1.146 ± 0.039	2.13MetArg: 2.13 ± 0.045	1.77MetSer: 1.77 ± 0.042	2.422MetThr: 2.422 ± 0.049	2.13MetVal: 2.13 ± 0.043	0.246MetTrp: 0.246 ± 0.016	0.34MetTyr: 0.34 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.164AsnAla: 3.164 ± 0.063	0.262AsnCys: 0.262 ± 0.015	1.505AsnAsp: 1.505 ± 0.045	1.16AsnGlu: 1.16 ± 0.039	0.912AsnPhe: 0.912 ± 0.028	2.397AsnGly: 2.397 ± 0.063	0.635AsnHis: 0.635 ± 0.025	1.62AsnIle: 1.62 ± 0.042	0.562AsnLys: 0.562 ± 0.023	2.435AsnLeu: 2.435 ± 0.045	0.757AsnMet: 0.757 ± 0.031	0.773AsnAsn: 0.773 ± 0.034	1.727AsnPro: 1.727 ± 0.046	0.742AsnGln: 0.742 ± 0.025	1.769AsnArg: 1.769 ± 0.044	1.242AsnSer: 1.242 ± 0.04	1.474AsnThr: 1.474 ± 0.038	1.897AsnVal: 1.897 ± 0.05	0.402AsnTrp: 0.402 ± 0.022	0.698AsnTyr: 0.698 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	7.034ProAla: 7.034 ± 0.112	0.554ProCys: 0.554 ± 0.026	4.552ProAsp: 4.552 ± 0.076	3.088ProGlu: 3.088 ± 0.06	1.88ProPhe: 1.88 ± 0.04	4.878ProGly: 4.878 ± 0.066	1.605ProHis: 1.605 ± 0.041	2.077ProIle: 2.077 ± 0.046	1.043ProLys: 1.043 ± 0.037	4.938ProLeu: 4.938 ± 0.075	1.524ProMet: 1.524 ± 0.039	1.21ProAsn: 1.21 ± 0.035	3.619ProPro: 3.619 ± 0.103	1.999ProGln: 1.999 ± 0.042	3.327ProArg: 3.327 ± 0.059	3.096ProSer: 3.096 ± 0.055	3.056ProThr: 3.056 ± 0.058	4.995ProVal: 4.995 ± 0.092	0.864ProTrp: 0.864 ± 0.033	1.29ProTyr: 1.29 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	4.96GlnAla: 4.96 ± 0.08	0.303GlnCys: 0.303 ± 0.018	1.814GlnAsp: 1.814 ± 0.04	1.543GlnGlu: 1.543 ± 0.044	1.062GlnPhe: 1.062 ± 0.033	2.674GlnGly: 2.674 ± 0.054	0.856GlnHis: 0.856 ± 0.032	1.891GlnIle: 1.891 ± 0.047	1.069GlnLys: 1.069 ± 0.036	2.497GlnLeu: 2.497 ± 0.045	1.059GlnMet: 1.059 ± 0.034	0.868GlnAsn: 0.868 ± 0.029	1.888GlnPro: 1.888 ± 0.047	1.551GlnGln: 1.551 ± 0.059	2.291GlnArg: 2.291 ± 0.053	1.736GlnSer: 1.736 ± 0.045	1.867GlnThr: 1.867 ± 0.044	2.87GlnVal: 2.87 ± 0.055	0.54GlnTrp: 0.54 ± 0.023	0.756GlnTyr: 0.756 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	8.573ArgAla: 8.573 ± 0.11	0.661ArgCys: 0.661 ± 0.025	4.482ArgAsp: 4.482 ± 0.073	3.676ArgGlu: 3.676 ± 0.081	2.742ArgPhe: 2.742 ± 0.056	5.112ArgGly: 5.112 ± 0.077	2.457ArgHis: 2.457 ± 0.052	4.306ArgIle: 4.306 ± 0.066	1.901ArgLys: 1.901 ± 0.051	8.157ArgLeu: 8.157 ± 0.106	2.428ArgMet: 2.428 ± 0.055	2.13ArgAsn: 2.13 ± 0.044	3.955ArgPro: 3.955 ± 0.072	2.949ArgGln: 2.949 ± 0.057	6.272ArgArg: 6.272 ± 0.108	3.181ArgSer: 3.181 ± 0.052	4.09ArgThr: 4.09 ± 0.059	5.014ArgVal: 5.014 ± 0.075	1.048ArgTrp: 1.048 ± 0.03	1.829ArgTyr: 1.829 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.0SerAla: 6.0 ± 0.084	0.629SerCys: 0.629 ± 0.028	2.94SerAsp: 2.94 ± 0.056	2.262SerGlu: 2.262 ± 0.051	2.164SerPhe: 2.164 ± 0.046	5.444SerGly: 5.444 ± 0.085	1.397SerHis: 1.397 ± 0.04	2.681SerIle: 2.681 ± 0.055	1.06SerLys: 1.06 ± 0.039	5.41SerLeu: 5.41 ± 0.073	1.573SerMet: 1.573 ± 0.035	1.347SerAsn: 1.347 ± 0.044	3.258SerPro: 3.258 ± 0.061	1.598SerGln: 1.598 ± 0.044	3.846SerArg: 3.846 ± 0.065	3.098SerSer: 3.098 ± 0.067	2.807SerThr: 2.807 ± 0.063	4.164SerVal: 4.164 ± 0.071	0.861SerTrp: 0.861 ± 0.031	1.41SerTyr: 1.41 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	6.318ThrAla: 6.318 ± 0.088	0.626ThrCys: 0.626 ± 0.025	3.195ThrAsp: 3.195 ± 0.059	2.257ThrGlu: 2.257 ± 0.047	1.984ThrPhe: 1.984 ± 0.047	5.445ThrGly: 5.445 ± 0.083	1.511ThrHis: 1.511 ± 0.037	2.951ThrIle: 2.951 ± 0.057	1.162ThrLys: 1.162 ± 0.034	6.286ThrLeu: 6.286 ± 0.079	1.458ThrMet: 1.458 ± 0.038	1.32ThrAsn: 1.32 ± 0.05	4.185ThrPro: 4.185 ± 0.072	2.065ThrGln: 2.065 ± 0.051	3.959ThrArg: 3.959 ± 0.065	3.028ThrSer: 3.028 ± 0.061	3.473ThrThr: 3.473 ± 0.07	4.202ThrVal: 4.202 ± 0.074	0.807ThrTrp: 0.807 ± 0.032	1.385ThrTyr: 1.385 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	8.863ValAla: 8.863 ± 0.109	0.788ValCys: 0.788 ± 0.031	3.775ValAsp: 3.775 ± 0.066	3.706ValGlu: 3.706 ± 0.074	2.459ValPhe: 2.459 ± 0.059	5.69ValGly: 5.69 ± 0.083	1.716ValHis: 1.716 ± 0.047	4.015ValIle: 4.015 ± 0.071	1.463ValLys: 1.463 ± 0.04	7.416ValLeu: 7.416 ± 0.095	2.584ValMet: 2.584 ± 0.051	1.851ValAsn: 1.851 ± 0.049	4.274ValPro: 4.274 ± 0.071	2.101ValGln: 2.101 ± 0.046	5.526ValArg: 5.526 ± 0.072	4.472ValSer: 4.472 ± 0.078	4.775ValThr: 4.775 ± 0.08	5.808ValVal: 5.808 ± 0.093	0.945ValTrp: 0.945 ± 0.033	1.353ValTyr: 1.353 ± 0.039	0.001ValXaa: 0.001 ± 0.001
Trp	1.162TrpAla: 1.162 ± 0.033	0.174TrpCys: 0.174 ± 0.014	0.743TrpAsp: 0.743 ± 0.03	0.548TrpGlu: 0.548 ± 0.023	0.483TrpPhe: 0.483 ± 0.023	1.106TrpGly: 1.106 ± 0.038	0.469TrpHis: 0.469 ± 0.02	0.68TrpIle: 0.68 ± 0.025	0.417TrpLys: 0.417 ± 0.021	1.656TrpLeu: 1.656 ± 0.042	0.446TrpMet: 0.446 ± 0.022	0.502TrpAsn: 0.502 ± 0.024	0.771TrpPro: 0.771 ± 0.028	0.582TrpGln: 0.582 ± 0.023	1.41TrpArg: 1.41 ± 0.04	0.822TrpSer: 0.822 ± 0.029	0.769TrpThr: 0.769 ± 0.027	0.862TrpVal: 0.862 ± 0.03	0.231TrpTrp: 0.231 ± 0.015	0.331TrpTyr: 0.331 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.438TyrAla: 2.438 ± 0.052	0.264TyrCys: 0.264 ± 0.015	1.52TyrAsp: 1.52 ± 0.043	1.06TyrGlu: 1.06 ± 0.031	0.858TyrPhe: 0.858 ± 0.032	2.165TyrGly: 2.165 ± 0.052	0.606TyrHis: 0.606 ± 0.026	0.996TyrIle: 0.996 ± 0.038	0.458TyrLys: 0.458 ± 0.025	2.171TyrLeu: 2.171 ± 0.046	0.523TyrMet: 0.523 ± 0.026	0.774TyrAsn: 0.774 ± 0.036	1.213TyrPro: 1.213 ± 0.034	0.788TyrGln: 0.788 ± 0.032	1.837TyrArg: 1.837 ± 0.048	1.155TyrSer: 1.155 ± 0.038	1.133TyrThr: 1.133 ± 0.04	1.621TyrVal: 1.621 ± 0.04	0.311TyrTrp: 0.311 ± 0.015	0.636TyrTyr: 0.636 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.001	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.012XaaXaa: 0.012 ± 0.009

Statistics based on 3303 proteins (1001832 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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