Amino acid dipepetide frequency for Posavirus sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.562AlaAla: 4.562 ± 0.0
1.629AlaCys: 1.629 ± 0.0
3.258AlaAsp: 3.258 ± 0.0
3.91AlaGlu: 3.91 ± 0.0
1.303AlaPhe: 1.303 ± 0.0
5.865AlaGly: 5.865 ± 0.0
0.978AlaHis: 0.978 ± 0.0
5.213AlaIle: 5.213 ± 0.0
2.281AlaLys: 2.281 ± 0.0
7.168AlaLeu: 7.168 ± 0.0
1.303AlaMet: 1.303 ± 0.0
2.933AlaAsn: 2.933 ± 0.0
2.607AlaPro: 2.607 ± 0.0
2.281AlaGln: 2.281 ± 0.0
2.933AlaArg: 2.933 ± 0.0
5.213AlaSer: 5.213 ± 0.0
4.562AlaThr: 4.562 ± 0.0
5.865AlaVal: 5.865 ± 0.0
0.978AlaTrp: 0.978 ± 0.0
3.91AlaTyr: 3.91 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.978CysAla: 0.978 ± 0.0
0.326CysCys: 0.326 ± 0.0
0.326CysAsp: 0.326 ± 0.0
0.652CysGlu: 0.652 ± 0.0
2.281CysPhe: 2.281 ± 0.0
1.629CysGly: 1.629 ± 0.0
0.652CysHis: 0.652 ± 0.0
1.303CysIle: 1.303 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.978CysLeu: 0.978 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.629CysAsn: 1.629 ± 0.0
0.652CysPro: 0.652 ± 0.0
0.652CysGln: 0.652 ± 0.0
0.326CysArg: 0.326 ± 0.0
2.933CysSer: 2.933 ± 0.0
1.955CysThr: 1.955 ± 0.0
1.303CysVal: 1.303 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.629CysTyr: 1.629 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.91AspAla: 3.91 ± 0.0
1.629AspCys: 1.629 ± 0.0
3.584AspAsp: 3.584 ± 0.0
1.955AspGlu: 1.955 ± 0.0
3.258AspPhe: 3.258 ± 0.0
4.236AspGly: 4.236 ± 0.0
1.629AspHis: 1.629 ± 0.0
3.584AspIle: 3.584 ± 0.0
1.955AspLys: 1.955 ± 0.0
4.562AspLeu: 4.562 ± 0.0
0.0AspMet: 0.0 ± 0.0
2.607AspAsn: 2.607 ± 0.0
6.191AspPro: 6.191 ± 0.0
0.652AspGln: 0.652 ± 0.0
1.955AspArg: 1.955 ± 0.0
5.213AspSer: 5.213 ± 0.0
2.933AspThr: 2.933 ± 0.0
4.888AspVal: 4.888 ± 0.0
0.652AspTrp: 0.652 ± 0.0
1.955AspTyr: 1.955 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.584GluAla: 3.584 ± 0.0
0.326GluCys: 0.326 ± 0.0
1.303GluAsp: 1.303 ± 0.0
1.955GluGlu: 1.955 ± 0.0
1.303GluPhe: 1.303 ± 0.0
1.303GluGly: 1.303 ± 0.0
0.978GluHis: 0.978 ± 0.0
3.584GluIle: 3.584 ± 0.0
2.281GluLys: 2.281 ± 0.0
6.517GluLeu: 6.517 ± 0.0
0.326GluMet: 0.326 ± 0.0
2.281GluAsn: 2.281 ± 0.0
2.281GluPro: 2.281 ± 0.0
0.652GluGln: 0.652 ± 0.0
0.978GluArg: 0.978 ± 0.0
4.888GluSer: 4.888 ± 0.0
2.281GluThr: 2.281 ± 0.0
3.91GluVal: 3.91 ± 0.0
0.0GluTrp: 0.0 ± 0.0
1.955GluTyr: 1.955 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.562PheAla: 4.562 ± 0.0
1.629PheCys: 1.629 ± 0.0
4.236PheAsp: 4.236 ± 0.0
3.258PheGlu: 3.258 ± 0.0
2.933PhePhe: 2.933 ± 0.0
2.281PheGly: 2.281 ± 0.0
0.652PheHis: 0.652 ± 0.0
3.584PheIle: 3.584 ± 0.0
2.281PheLys: 2.281 ± 0.0
2.607PheLeu: 2.607 ± 0.0
2.281PheMet: 2.281 ± 0.0
4.236PheAsn: 4.236 ± 0.0
2.281PhePro: 2.281 ± 0.0
1.955PheGln: 1.955 ± 0.0
0.652PheArg: 0.652 ± 0.0
4.236PheSer: 4.236 ± 0.0
2.933PheThr: 2.933 ± 0.0
3.258PheVal: 3.258 ± 0.0
0.326PheTrp: 0.326 ± 0.0
2.607PheTyr: 2.607 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.562GlyAla: 4.562 ± 0.0
0.978GlyCys: 0.978 ± 0.0
5.213GlyAsp: 5.213 ± 0.0
2.281GlyGlu: 2.281 ± 0.0
4.236GlyPhe: 4.236 ± 0.0
2.281GlyGly: 2.281 ± 0.0
0.0GlyHis: 0.0 ± 0.0
2.607GlyIle: 2.607 ± 0.0
2.933GlyLys: 2.933 ± 0.0
3.91GlyLeu: 3.91 ± 0.0
0.652GlyMet: 0.652 ± 0.0
1.629GlyAsn: 1.629 ± 0.0
2.933GlyPro: 2.933 ± 0.0
1.955GlyGln: 1.955 ± 0.0
1.629GlyArg: 1.629 ± 0.0
5.539GlySer: 5.539 ± 0.0
2.933GlyThr: 2.933 ± 0.0
4.236GlyVal: 4.236 ± 0.0
0.978GlyTrp: 0.978 ± 0.0
2.933GlyTyr: 2.933 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.652HisAla: 0.652 ± 0.0
0.652HisCys: 0.652 ± 0.0
1.303HisAsp: 1.303 ± 0.0
0.326HisGlu: 0.326 ± 0.0
0.978HisPhe: 0.978 ± 0.0
0.326HisGly: 0.326 ± 0.0
0.326HisHis: 0.326 ± 0.0
0.326HisIle: 0.326 ± 0.0
0.978HisLys: 0.978 ± 0.0
1.629HisLeu: 1.629 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.652HisAsn: 0.652 ± 0.0
2.281HisPro: 2.281 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.978HisArg: 0.978 ± 0.0
2.933HisSer: 2.933 ± 0.0
0.326HisThr: 0.326 ± 0.0
2.607HisVal: 2.607 ± 0.0
0.326HisTrp: 0.326 ± 0.0
1.303HisTyr: 1.303 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.91IleAla: 3.91 ± 0.0
1.303IleCys: 1.303 ± 0.0
4.562IleAsp: 4.562 ± 0.0
1.629IleGlu: 1.629 ± 0.0
2.607IlePhe: 2.607 ± 0.0
3.584IleGly: 3.584 ± 0.0
0.978IleHis: 0.978 ± 0.0
3.91IleIle: 3.91 ± 0.0
2.281IleLys: 2.281 ± 0.0
5.213IleLeu: 5.213 ± 0.0
0.652IleMet: 0.652 ± 0.0
4.236IleAsn: 4.236 ± 0.0
4.236IlePro: 4.236 ± 0.0
1.303IleGln: 1.303 ± 0.0
2.281IleArg: 2.281 ± 0.0
4.888IleSer: 4.888 ± 0.0
4.562IleThr: 4.562 ± 0.0
3.584IleVal: 3.584 ± 0.0
0.652IleTrp: 0.652 ± 0.0
2.607IleTyr: 2.607 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.258LysAla: 3.258 ± 0.0
0.652LysCys: 0.652 ± 0.0
1.303LysAsp: 1.303 ± 0.0
0.652LysGlu: 0.652 ± 0.0
1.955LysPhe: 1.955 ± 0.0
3.91LysGly: 3.91 ± 0.0
0.652LysHis: 0.652 ± 0.0
1.629LysIle: 1.629 ± 0.0
1.629LysLys: 1.629 ± 0.0
4.888LysLeu: 4.888 ± 0.0
0.978LysMet: 0.978 ± 0.0
2.933LysAsn: 2.933 ± 0.0
1.629LysPro: 1.629 ± 0.0
0.978LysGln: 0.978 ± 0.0
1.303LysArg: 1.303 ± 0.0
5.213LysSer: 5.213 ± 0.0
4.562LysThr: 4.562 ± 0.0
4.888LysVal: 4.888 ± 0.0
0.326LysTrp: 0.326 ± 0.0
3.584LysTyr: 3.584 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.888LeuAla: 4.888 ± 0.0
0.978LeuCys: 0.978 ± 0.0
4.562LeuAsp: 4.562 ± 0.0
3.91LeuGlu: 3.91 ± 0.0
7.168LeuPhe: 7.168 ± 0.0
4.562LeuGly: 4.562 ± 0.0
1.629LeuHis: 1.629 ± 0.0
3.91LeuIle: 3.91 ± 0.0
4.888LeuLys: 4.888 ± 0.0
5.865LeuLeu: 5.865 ± 0.0
1.629LeuMet: 1.629 ± 0.0
2.933LeuAsn: 2.933 ± 0.0
4.236LeuPro: 4.236 ± 0.0
1.629LeuGln: 1.629 ± 0.0
2.933LeuArg: 2.933 ± 0.0
11.73LeuSer: 11.73 ± 0.0
5.213LeuThr: 5.213 ± 0.0
7.168LeuVal: 7.168 ± 0.0
0.978LeuTrp: 0.978 ± 0.0
4.562LeuTyr: 4.562 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.303MetAla: 1.303 ± 0.0
0.326MetCys: 0.326 ± 0.0
0.326MetAsp: 0.326 ± 0.0
1.303MetGlu: 1.303 ± 0.0
0.326MetPhe: 0.326 ± 0.0
0.652MetGly: 0.652 ± 0.0
0.978MetHis: 0.978 ± 0.0
1.629MetIle: 1.629 ± 0.0
1.955MetLys: 1.955 ± 0.0
1.629MetLeu: 1.629 ± 0.0
0.326MetMet: 0.326 ± 0.0
2.281MetAsn: 2.281 ± 0.0
1.303MetPro: 1.303 ± 0.0
0.652MetGln: 0.652 ± 0.0
0.652MetArg: 0.652 ± 0.0
1.955MetSer: 1.955 ± 0.0
1.303MetThr: 1.303 ± 0.0
0.326MetVal: 0.326 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.652MetTyr: 0.652 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.562AsnAla: 4.562 ± 0.0
1.629AsnCys: 1.629 ± 0.0
1.955AsnAsp: 1.955 ± 0.0
2.607AsnGlu: 2.607 ± 0.0
1.955AsnPhe: 1.955 ± 0.0
3.584AsnGly: 3.584 ± 0.0
0.652AsnHis: 0.652 ± 0.0
3.91AsnIle: 3.91 ± 0.0
2.607AsnLys: 2.607 ± 0.0
5.213AsnLeu: 5.213 ± 0.0
1.303AsnMet: 1.303 ± 0.0
3.584AsnAsn: 3.584 ± 0.0
4.236AsnPro: 4.236 ± 0.0
1.955AsnGln: 1.955 ± 0.0
0.652AsnArg: 0.652 ± 0.0
7.494AsnSer: 7.494 ± 0.0
3.584AsnThr: 3.584 ± 0.0
3.258AsnVal: 3.258 ± 0.0
0.652AsnTrp: 0.652 ± 0.0
2.281AsnTyr: 2.281 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.584ProAla: 3.584 ± 0.0
0.326ProCys: 0.326 ± 0.0
4.562ProAsp: 4.562 ± 0.0
3.258ProGlu: 3.258 ± 0.0
4.236ProPhe: 4.236 ± 0.0
1.629ProGly: 1.629 ± 0.0
0.652ProHis: 0.652 ± 0.0
3.584ProIle: 3.584 ± 0.0
2.281ProLys: 2.281 ± 0.0
4.562ProLeu: 4.562 ± 0.0
1.955ProMet: 1.955 ± 0.0
3.584ProAsn: 3.584 ± 0.0
2.933ProPro: 2.933 ± 0.0
1.955ProGln: 1.955 ± 0.0
1.629ProArg: 1.629 ± 0.0
3.584ProSer: 3.584 ± 0.0
5.539ProThr: 5.539 ± 0.0
2.607ProVal: 2.607 ± 0.0
0.326ProTrp: 0.326 ± 0.0
1.955ProTyr: 1.955 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.652GlnAla: 0.652 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.303GlnAsp: 1.303 ± 0.0
0.652GlnGlu: 0.652 ± 0.0
0.978GlnPhe: 0.978 ± 0.0
3.258GlnGly: 3.258 ± 0.0
0.326GlnHis: 0.326 ± 0.0
2.607GlnIle: 2.607 ± 0.0
1.955GlnLys: 1.955 ± 0.0
1.629GlnLeu: 1.629 ± 0.0
0.652GlnMet: 0.652 ± 0.0
0.978GlnAsn: 0.978 ± 0.0
0.326GlnPro: 0.326 ± 0.0
0.326GlnGln: 0.326 ± 0.0
0.0GlnArg: 0.0 ± 0.0
3.258GlnSer: 3.258 ± 0.0
1.955GlnThr: 1.955 ± 0.0
4.236GlnVal: 4.236 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
2.607GlnTyr: 2.607 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.629ArgAla: 1.629 ± 0.0
0.978ArgCys: 0.978 ± 0.0
1.303ArgAsp: 1.303 ± 0.0
1.629ArgGlu: 1.629 ± 0.0
2.607ArgPhe: 2.607 ± 0.0
1.629ArgGly: 1.629 ± 0.0
0.978ArgHis: 0.978 ± 0.0
0.652ArgIle: 0.652 ± 0.0
2.607ArgLys: 2.607 ± 0.0
1.303ArgLeu: 1.303 ± 0.0
1.629ArgMet: 1.629 ± 0.0
1.629ArgAsn: 1.629 ± 0.0
1.303ArgPro: 1.303 ± 0.0
0.326ArgGln: 0.326 ± 0.0
2.281ArgArg: 2.281 ± 0.0
2.281ArgSer: 2.281 ± 0.0
2.281ArgThr: 2.281 ± 0.0
3.584ArgVal: 3.584 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
0.652ArgTyr: 0.652 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.539SerAla: 5.539 ± 0.0
2.281SerCys: 2.281 ± 0.0
6.191SerAsp: 6.191 ± 0.0
3.91SerGlu: 3.91 ± 0.0
3.584SerPhe: 3.584 ± 0.0
5.539SerGly: 5.539 ± 0.0
2.281SerHis: 2.281 ± 0.0
6.191SerIle: 6.191 ± 0.0
5.865SerLys: 5.865 ± 0.0
11.404SerLeu: 11.404 ± 0.0
2.933SerMet: 2.933 ± 0.0
6.191SerAsn: 6.191 ± 0.0
2.281SerPro: 2.281 ± 0.0
3.258SerGln: 3.258 ± 0.0
3.258SerArg: 3.258 ± 0.0
8.798SerSer: 8.798 ± 0.0
6.517SerThr: 6.517 ± 0.0
5.213SerVal: 5.213 ± 0.0
0.326SerTrp: 0.326 ± 0.0
6.517SerTyr: 6.517 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.517ThrAla: 6.517 ± 0.0
1.629ThrCys: 1.629 ± 0.0
3.258ThrAsp: 3.258 ± 0.0
1.629ThrGlu: 1.629 ± 0.0
3.91ThrPhe: 3.91 ± 0.0
2.933ThrGly: 2.933 ± 0.0
0.652ThrHis: 0.652 ± 0.0
2.933ThrIle: 2.933 ± 0.0
2.607ThrLys: 2.607 ± 0.0
6.843ThrLeu: 6.843 ± 0.0
0.652ThrMet: 0.652 ± 0.0
4.236ThrAsn: 4.236 ± 0.0
3.258ThrPro: 3.258 ± 0.0
1.629ThrGln: 1.629 ± 0.0
2.607ThrArg: 2.607 ± 0.0
4.888ThrSer: 4.888 ± 0.0
5.865ThrThr: 5.865 ± 0.0
6.843ThrVal: 6.843 ± 0.0
0.652ThrTrp: 0.652 ± 0.0
1.955ThrTyr: 1.955 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.539ValAla: 5.539 ± 0.0
0.978ValCys: 0.978 ± 0.0
5.865ValAsp: 5.865 ± 0.0
3.584ValGlu: 3.584 ± 0.0
3.258ValPhe: 3.258 ± 0.0
2.281ValGly: 2.281 ± 0.0
1.629ValHis: 1.629 ± 0.0
5.539ValIle: 5.539 ± 0.0
3.91ValLys: 3.91 ± 0.0
5.865ValLeu: 5.865 ± 0.0
0.652ValMet: 0.652 ± 0.0
5.539ValAsn: 5.539 ± 0.0
6.517ValPro: 6.517 ± 0.0
2.607ValGln: 2.607 ± 0.0
1.955ValArg: 1.955 ± 0.0
8.146ValSer: 8.146 ± 0.0
3.91ValThr: 3.91 ± 0.0
7.168ValVal: 7.168 ± 0.0
0.978ValTrp: 0.978 ± 0.0
3.258ValTyr: 3.258 ± 0.0
0.326ValXaa: 0.326 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.652TrpAsp: 0.652 ± 0.0
0.652TrpGlu: 0.652 ± 0.0
0.652TrpPhe: 0.652 ± 0.0
0.652TrpGly: 0.652 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.652TrpIle: 0.652 ± 0.0
0.652TrpLys: 0.652 ± 0.0
0.978TrpLeu: 0.978 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.978TrpAsn: 0.978 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.326TrpGln: 0.326 ± 0.0
0.978TrpArg: 0.978 ± 0.0
0.652TrpSer: 0.652 ± 0.0
0.978TrpThr: 0.978 ± 0.0
0.978TrpVal: 0.978 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.562TyrAla: 4.562 ± 0.0
1.955TyrCys: 1.955 ± 0.0
2.281TyrAsp: 2.281 ± 0.0
2.933TyrGlu: 2.933 ± 0.0
2.933TyrPhe: 2.933 ± 0.0
2.281TyrGly: 2.281 ± 0.0
2.281TyrHis: 2.281 ± 0.0
1.629TyrIle: 1.629 ± 0.0
0.978TyrLys: 0.978 ± 0.0
2.607TyrLeu: 2.607 ± 0.0
1.629TyrMet: 1.629 ± 0.0
2.607TyrAsn: 2.607 ± 0.0
3.258TyrPro: 3.258 ± 0.0
2.607TyrGln: 2.607 ± 0.0
1.303TyrArg: 1.303 ± 0.0
4.236TyrSer: 4.236 ± 0.0
1.303TyrThr: 1.303 ± 0.0
3.91TyrVal: 3.91 ± 0.0
1.629TyrTrp: 1.629 ± 0.0
2.281TyrTyr: 2.281 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.326XaaPhe: 0.326 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3070 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski